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BI-847325
BI-847325 is an orally bioavailable, and selective dual MEK / Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Alternative Names: BI-847325; BI 847325; BI847325. Grades: 98%. CAS No. 1207293-36-4. Molecular formula: C29H28N4O2. Mole weight: 464.56.
Biapenem
Biapenem is a carbapenem antibiotic with in vitro activity against anaerobes. Alternative Names: Omegacin; Biapenern; L-627; L 627; L627. Grades: 98%. CAS No. 120410-24-4. Molecular formula: C15H18N4O4S. Mole weight: 350.39282.
Biapigenin
It is isolated from the herbs of Hypericum perforatum L. Alternative Names: [3,8'-Bi-4H-1-benzopyran]-4,4'-dione, 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-; 5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)[3,8'-bi-4H-1-benzopyran]-4,4'-dione; 3,8''-Biapigenin; 8,3''-Biapigenin; I3,II8-Biapigenin. Grades: 98%. CAS No. 101140-06-1. Molecular formula: C30H18O10. Mole weight: 538.46.
Bifenox-[d3]
Bifenox-[d3] is a labelled compound of Bifenox which is a herbicide. Alternative Names: Bifenox-d3 (2,4-dichlorophenoxy-d3); 5-(2,4-Dichlorophenoxy)-2-nitrobenzoic Acid Methyl Ester-d3; 2,4-Dichlorophenyl 3-(Methoxycarbonyl)-4-nitrophenyl Ether-d3; Methyl 5-(2,4-Dichlorophenoxy)-2-nitrobenzoate. Grades: > 98%. Molecular formula: C14H6D3Cl2NO5. Mole weight: 345.15.
Bi-linderone
Bi-linderone is a natural miscellaneou found in the roots of Lindera aggregata( Sims) Kosterm, it shows significant activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 microg/mL. Grades: >95%. CAS No. 1227375-09-8. Molecular formula: C34H32O10. Mole weight: 600.6.
Bilobalide
Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba. Alternative Names: (-)-Bilobalide; Vitexicarpim; (3aS,5aR,8aS)-9R-(1,1-dimethylethyl)-10,10aS-dihydro-8R,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione. Grades: >98%. CAS No. 33570-04-6. Molecular formula: C15H18O8. Mole weight: 326.30.
BINAP, mono-oxide
BINAP, mono-oxide (CAS# 204862-91-9 ) is a useful research chemical. Grades: 95 %. CAS No. 204862-91-9. Molecular formula: C44H32OP2. Mole weight: 638.69.
Binodenoson
Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor agonist. It is used to diagnose coronary artery disease. Uses: Purinergic p1 receptor agonists. Alternative Names: MRE0470; MRE-0470; WRC-0470; SHA-174; 2-((Cyclohexylmethylene)hydrazino)adenosine; 2-(Cyclohexylmethylidene hydrazino) adenosine; 2-[2-(Cyclohexylmethylene)hydrazinyl]adenosine; 2-(Cyclohexylmethylidenehydrazino)adenosine; SHA 211; WRC 0470. Grades: 95%. CAS No. 144348-08-3. Molecular formula: C17H25N7O4. Mole weight: 391.42.
BIO 5192
BIO 5192 is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM) with selectivity for α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053,> 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). BIO 5192 causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Alternative Names: BIO-5192; AMD-15057; BIO 5192; AMD 15057; BIO5192; AMD15057; (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid. Grades: ≥98% by HPLC. CAS No. 327613-57-0. Molecular formula: C38H46Cl2N6O8S. Mole weight: 817.78.
Biochanin A
Biochanin A. CAS No. 491-80-5.
Biorobin
Biorobin is a natural flavonoid found in the herbs of Cassia occidentalis. Alternative Names: 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;Kaempferol 3-O-robinoside. Grades: >98%. CAS No. 17297-56-2. Molecular formula: C27H30O15. Mole weight: 594.53.
(+)-Biotin azidopropylamide
(+)-Biotin azidopropylamide, a scientific compound, is a highly effective labeling agent for proteins aimed at facilitating their affinity purification and detection. Its multifaceted role spans across understanding protein-protein interactions, molecular biology, and oncology whereby its application in the development of diagnostic assays for cancer has proven resourceful. Alternative Names: N-(3-Azidopropyl)biotinamide; biotin-azide. CAS No. 908007-17-0. Molecular formula: C13H22N6O2S. Mole weight: 326.42.
Biotin-PEG4-alkyne
Biotin-PEG4-alkyne is a click chemistry biotinylation tool. Alternative Names: Acetylene-PEG4-biotin conjugate; (3aS,4S,6aR)-Biotin-PEG4-Alkyne. CAS No. 1262681-31-1. Molecular formula: C21H35N3O6S. Mole weight: 457.59.
Biotin-PEG4-OH
Biotin-PEG4-OH is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG4-OH can be used in the synthesis of a series of PROTACs. Alternative Names: Biotin-PEG4-alcohol; N-(2-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide. Grades: 95%. CAS No. 1778736-18-7. Molecular formula: C18H33N3O6S. Mole weight: 419.54.
Biotin-PEG4-Picolyl azide
Biotin-PEG4-Picolyl azide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG4-Picolyl azide can be used in the synthesis of a series of PROTACs. Alternative Names: Biotin picolyl azide. Grades: ≥95%. CAS No. 2222687-71-8. Molecular formula: C27H42N8O7S. Mole weight: 622.74.
Biotinyl Tyramide
Biotinyl Tyramide is a biotin derivative used as a reagent for signal amplification in IHC and in situ hybridization (ISH). Alternative Names: Biotin-Phenol; (3aS,4S,6aR)-Hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide. Grades: 95% by HNMR. CAS No. 41994-02-9. Molecular formula: C18H25N3O3S. Mole weight: 363.47.
BIS(1-BUTYLPENTYL) DECANE-1,10-DIYL DIGLUTARATE
Abbreviated as Sec or U, in older publications also as Se-Cys, as a building block of selenoproteins, this 21st proteinogenic amino acid exists naturally in three domains of life, but not in every lineage. Uses: Used for the characterization of total sodium concentration in human blood plasma; also used for the preparation of nitrite-selective membrane electrode, used for the potentiometric determination of nad(p)h coenzymes. Alternative Names: 5-O-nonan-5-yl 1-O-[10-(5-nonan-5-yloxy-5-oxopentanoyl)oxydecyl] pentanedioate; ETH 469; AC1ND8J0; 30585_FLUKA; ETH-469; ZINC100650269; 5-O-nonan-5-yl 1-O-[10-(5-nonan-5-yloxy-5-oxopentanoyl)oxydecyl] pentanedioate. Grades: ≥ 95.0%. CAS No. 101342-76-1. Molecular formula: C38H70O8. Mole weight: 654.96.
bis[6-(5,6-dihydrochelerythrinyl)]amine
Bis[6-(5,6-dihydrochelerythrinyl)]amine is found in Zanthoxylum nitidum, which shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus. Alternative Names: 13,13'-Iminobis(1,2-dimethoxy-12-methyl-12,13-dihydro[1,3]benzodioxolo[5,6-c]phenanthridine); Bis(1,2-dimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-13-yl)amine. Grades: > 95%. CAS No. 165393-48-6. Molecular formula: C42H37N3O8. Mole weight: 711.76.
Bisabola-3,10-dien-2-one
Bisabola-3,10-dien-2-one is isolated from the leaves of Alpinia intermedia. Alternative Names: 1-Bisabolone; 6R,7R-Bisabolone; (6R)-3-methyl-6-[(2S)-6-methylhept-5-en-2-yl]cyclohex-2-en-1-one. Grades: 98.0%. CAS No. 61432-71-1. Molecular formula: C15H24O. Mole weight: 220.356.
Bis(L-Valine) Ester Ganciclovir Trifluoroacetic Acid Salt
Bis(L-Valine) Ester Ganciclovir Trifluoroacetic Acid Salt is an impurity of Ganciclovir. Ganciclovir is a nucleoside analog structurally related to Acyclovir. Ganciclovir is an antiviral. Alternative Names: L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-1,3-propanediyl Ester Trifluoroacetic Acid Salt; Ganciclovir Impurity F Trifluoroacetic Acid Salt. Grades: 95%. Molecular formula: C19H31N7O6.x(C2HF3O2). Mole weight: 453.49 + x(114.02).
Bismuth Subsalicylate
Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2. Uses: Antidiarrheals. Alternative Names: Bismuth oxysalicylate; Bismuth oxide salicylate; Wismutsubsalicylat; Bismuth(III) subsalicylate. Grades: Content(Bi) 56.0%~59.4%. Content(total salicylates) 36.5%~39.3%. CAS No. 14882-18-9. Molecular formula: C7H5BiO4. Mole weight: 362.09.
Bis(N-diazo)-tris(O-acetyl)-2-deoxystreptamine
Bis(N-diazo)-tris(O-acetyl)-2-deoxystreptamine (CAS# 90852-19-0 ) is a useful research chemical. Alternative Names: [(1S,3R,4S,6R)-2,3-diacetyloxy-4,6-diazidocyclohexyl] acetate. CAS No. 90852-19-0. Molecular formula: C12H16N6O6. Mole weight: 340.29.
bis-N-Succinimidyl diglycolic acid
Bis-N-Succinimidyl diglycolic acid, a widely utilized cross-linking reagent, plays a pivotal role in biomedicine. Its reaction with proteins' primary amines leads to covalent binding, which is instrumental in exploring protein-protein interactions. This reagent is also an indispensable component in the development of drug delivery and biomaterials to combat various diseases, including cancer. Alternative Names: Bis-N-succinimidyl diglycolic acid, 2,2-Oxydiacetic acid bis-N-succinimidyl ester; DIG(NHS)2. Grades: 95%. CAS No. 373614-12-1. Molecular formula: C12H12N2O9. Mole weight: 328.232.
Bis-PEG1-NHS ester
Bis-PEG1-NHS ester is a non-cleavable 1-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Alternative Names: Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-oxydipropionate; Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-oxydipropanoate; 2,5-Pyrrolidinedione, 1,1'-[oxybis[(1-oxo-3,1-propanediyl)oxy]]bis-; Di-NHS Ester-PEG1; 1,1'-{Oxybis[(1-oxo-3,1-propanediyl)oxy]}di(2,5-pyrrolidinedione). Grades: ≥98%. CAS No. 65869-64-9. Molecular formula: C14H16N2O9. Mole weight: 356.28.
Bisphenol A bis(2,3-dihydroxypropyl) ether
Applications: Bisphenol A Bis(2,3-dihydroxypropyl) ether is used as a standard for determining toxic monomers released from polymers of the inner coating of cans. Alternative Names: 2,2-Bis[4-(2,3-dihydroxypropoxy)phenyl]propane. Grades: ≥97.0% (HPLC). CAS No. 5581-32-8. Molecular formula: C21H28O6. Mole weight: 376.44.
Bis(triphenylphosphine)nickel(II)chloride
Bis(triphenylphosphine)nickel(II)chloride. CAS No. 14264-16-5.
Bitopertin
Bitopertin is a potent and noncompetitive glycine reuptake inhibitor (GlyT1). It is effective in reducing the negative symptoms when given in combination with second generation antipsychotics. It is currently in Phase III trials for the treatment of the negative symptoms of schizophrenia. Alternative Names: RG-1678; RG1678; RG 1678; R-1678; R1678; R 1678; RO4917838; RO-4917838; RO 4917838; Bitopertin. Grades: >98%. CAS No. 845614-11-1. Molecular formula: C21H20F7N3O4S. Mole weight: 543.46.
BL-918
BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1). It induces cytoprotective autophagy for Parkinson's disease treatment. It protected against MPTP-induced motor dysfunction and loss of dopaminergic neurons by targeting ULK1-modulated autophagy in mouse models of PD. Alternative Names: BL 918; BL918; (R)-2-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-N-(2,4-difluorophenyl)-2-phenylacetamide. Grades: ≥98%. CAS No. 2101517-69-3. Molecular formula: C23H15F8N3OS. Mole weight: 533.4.
Blinin
Blinin is a diterpene originally isolated from C. blini. Uses: Antimalarial. Alternative Names: 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(Acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone; 2(5H)-Furanone, 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-; 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(Acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone. Grades: >98%. CAS No. 125675-09-4. Molecular formula: C22H32O6. Mole weight: 392.49.
BLU-667
BLU-667 (Pralsetinib) is a highly effective and selective RET inhibitor. It has an IC50 of 0.3-0.4 nM for the fusion of WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET. Alternative Names: Pralsetinib. Grades: ≥98% by HPLC. CAS No. 2097132-94-8. Molecular formula: C27H32FN9O2. Mole weight: 533.6.
BLU9931
BLU9931 is a potent and irreversible small-molecule inhibitor of FGFR4, as a targeted therapy to treat patients with HCC whose tumors have an activated FGFR4 signaling pathway. BLU9931 is exquisitely selective for FGFR4 versus other FGFR family members and all other kinases. Alternative Names: BLU9931; BLU-9931; BLU 9931. Grades: 98%. CAS No. 1538604-68-0. Molecular formula: C26H22Cl2N4O3. Mole weight: 509.38.
Blumeatin
Blumeatin is found in tea and is extracted from the herbs of Blumea balsamifera. It can enhance adipocyte differentiation by increasing triglyceride levels in 3T3L1 cells. It also can increase the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes GLUT4 and aP2. It inhibits the increase of liver triglyceride and serum alanine aminotransferase, and increases serum beta-lipoprotein, liver glycogen and triglyceride content in CCl4-intoxicated rats, thus shorten the pentobarbital sleeping time in CCl4-intoxicated mice. It shows free radical scavenging activity, xanthine oxidase (XO) inhibitory activity and antioxidant properties. It can protect liver against injury induced by CCl4 and TAA. Alternative Names: 5,3',5'-Trihydroxy-7-methoxyflavanone; 2-(3,5-Dihydroxyphenyl)-5-hydroxy-7-methoxy-3,4-dihydro-2H-1-benzopyran-4-one. CAS No. 118024-26-3. Molecular formula: C16H14O6. Mole weight: 302.28.
BML-277
BML-277 is a selective APT-competitive inhibitor of the DNA damage response signaling enzyme CHK2 ( IC50 =15 nM). Uses: A selective apt-competitive inhibitor. Alternative Names: BML-277; BML 277; BML277; Chk2 Inhibitor II;2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide. Grades: ≥98%. CAS No. 516480-79-8. Molecular formula: C20H14ClN3O2. Mole weight: 363.80.
BML-284
BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Alternative Names: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. Grades: >98%. CAS No. 853220-52-7. Molecular formula: C19H18N4O3. Mole weight: 350.37.
BMS303141
BMS 303141 is a cell-permeable, 2-hydroxy-N-arylbenzenesulfonamide that inhibits ACL with an IC50 value of 0.13 μM. BMS 303141 has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia. Alternative Names: BMS303141; BMS-303141; BMS 303141. CAS No. 943962-47-8. Molecular formula: C19H15Cl2NO4S. Mole weight: 424.30.
BMS-663068
BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection. It is a prodrug for BMS-626529, which binds to the viral envelope glycoprotein gp120 and interferes with attachment of the virus to the cellular CD4 receptor. Alternative Names: Fostemsavir; BMS-663068; BMS 663068; BMS663068. Grades: >98%. CAS No. 864953-29-7. Molecular formula: C25H26N7O8P. Mole weight: 583.49.
BMS-779788
BMS-779788 is a LXR partial agonist with IC50 values of 68 nM and 14 nM for LXRα and LXRβ respectively. BMS-779788 induces LXR target genes in blood in vivo with EC50 value of 610 nM, and significantly increases plasma triglyceride and LDL cholesterol. Alternative Names: BMS-779788; BMS 779788; BMS779788; BMS-788; BMS 788; BMS788; XL-652; XL652; XL652; EXEL 04286652; EXEL04286652; EXEL-04286652;; 2-[2-[2-(2-chlorophenyl)propan-2-yl]-1-[4-(3-methylsulfonylphenyl)phenyl]imidazol-4-yl]propan-2-ol. CAS No. 918348-67-1. Molecular formula: C28H29ClN2O3S. Mole weight: 509.061.
BMS-791325 HCl
BMS-791325 HCl is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase. BMS-791325 inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 at 50% inhibitory concentrations (IC50 < 28 nM). In cell culture, BMS-791325 inhibited replication of HCV subgenomic replicons representing genotypes 1a and 1b at 50% effective concentrations (EC50s) of 3 nM and 6 nM, respectively, with similar (3 to 18 nM) values for genotypes 3a, 4a, and 5a. BMS-791325 was found to have distinguishing antiviral, safety, and pharmacokinetic properties that resulted in its selection for clinical evaluation. BMS-791325 is currently under Phase III trials. Alternative Names: Beclabuvir hydrochloride; BMS-791325 HCl; BMS 791325 HCl; BMS791325 HCl. Grades:> 98%. CAS No. 958002-36-3. Molecular formula: C36H46ClN5O5S. Mole weight: 696.304.
BMS-794833
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM. Alternative Names: BMS794833; BMS 794833. Grades: 0.98. CAS No. 1174046-72-0. Molecular formula: C23H15ClF2N4O3. Mole weight: 468.845.
BMS-911543
BMS-911543 is an orally available JAK inhibitor with selectivity for JAK2. It inhibts JAK2, thereby preventing the JAK / STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation. Alternative Names: BMS 911543. Grades: >98%. CAS No. 1271022-90-2. Molecular formula: C23H28N8O. Mole weight: 432.532.
BMS 986020
BMS 986020 is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. It inhibits bile acid and phospholipid transporters with IC50s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS 986020 is used for the treatment of idiopathic pulmonary fibrosis (IPF). Alternative Names: BMS-986020; BMS986020. Grades: ≥98%. CAS No. 1257213-50-5. Molecular formula: C29H26N2O5. Mole weight: 482.5.
BMS-986120
BMS-986120, an imidazoles derivative, has been found to be a PAR4 antagonist that could probably be effective against thrombus propagation and pathological vascular occlusion. It was just completed a Phase I trail in in Thrombosis. Alternative Names: BMS-986120; BMS 986120; BMS986120; 4-(4-(((6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)-5-methylthiazol-2-yl)morpholine. Grades: 98%. CAS No. 1478712-37-6. Molecular formula: C23H23N5O5S2. Mole weight: 513.59.
BMS-986195
BMS-986195 is a Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 0.1 nM. Alternative Names: Branebrutinib; BMS 986195; BMS986195. Grades: ≥98% by HPLC. CAS No. 1912445-55-6. Molecular formula: C20H23FN4O2. Mole weight: 370.42.
Boc-Val-Cit-PAB-PNP
Boc-Val-Cit-PAB-PNP. Alternative Names: EX-A4143. Grades: 95%. CAS No. 870487-10-8. Molecular formula: C30H40N6O10. Mole weight: 644.7.
BODIPY 493/503 carboxylic acid
BODIPY 493/503 carboxylic acid. Alternative Names: 10-(2-Carboxyethyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide. CAS No. 216961-95-4. Molecular formula: C16H19BF2N2O2. Mole weight: 320.15.
BODIPY 493/503 NHS Ester
BODIPY 493/503 NHS Ester is a green-fluorescent dye that is reactive with primary amines on peptides, proteins, modified nucleotides, biopolymers, and other amine-containing biomolecules. This compound is relatively insensitive to environment and pH changes. Alternative Names: 10-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide. CAS No. 216961-98-7. Molecular formula: C20H22BF2N3O4. Mole weight: 417.22.
BODIPY 576/589
BODIPY 576/589 is a red-fluorescent dye that is reactive with primary amines on peptides, proteins, modified nucleotides, biopolymers and other amine-containing biomolecules using a carbodiimide like EDAC or DIPC. This compound is relatively insensitive to environment and pH changes. Alternative Names: EverFluor 576/589, Acid. Molecular formula: C16H14BF2N3O2. Mole weight: 329.11.
BODIPY 576/589 SE
BODIPY 576/589 SE is a red-fluorescent dye that is reactive with primary amines on peptides, proteins, modified nucleotides, biopolymers and other amine-containing biomolecules. It is non-ionic, and relatively insensitive to environment and pH changes. Alternative Names: EverFluor 576/589 SE; BODIPY 576/589 NHS Ester. Molecular formula: C20H17BF2N4O4. Mole weight: 426.18.
BODIPY FL C5 is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers. It is suitable for live-cell membrane experiments. This carboxylic acid may react with amines using a carbodiimide like EDAC or DIPC and to form ester-linked conjugates or acid-halide products. It is relatively insensitive to environment and pH changes. Alternative Names: EverFluor FL C5; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Pentanoic Acid. Molecular formula: C16H19BF2N2O2. Mole weight: 320.14.
Boehmenan
Boehmenan is a natural lignan found in the herbs of Euphorbia hirta Linn, it inhibits PTP1B activity in a competitive manner and may also inhibit the Wnt signal by decreasing β-catenin levels. Alternative Names: 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid 3-[2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-[[[3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]oxy]methyl]-7-methoxybenzofuran-5-yl]propyl ester. Grades: >97%. CAS No. 57296-22-7. Molecular formula: C40H40O12. Mole weight: 712.8.
Boeravinone B
Boeravinone B isolated from the roots of Boerhaavia coccinea. Alternative Names: 10-Methyl-6,9,11-trihydroxy[1]benzopyrano[3,4-b][1]benzopyran-12(6H)-one. Grades: 0.98. CAS No. 114567-34-9. Molecular formula: C17H12O6. Mole weight: 312.3.
Bonducellpin D
Bonducellpin D is a natural diterpenoid compound found in several plants. . Alternative Names: (3bS,3b1R,5aR,6S,6aR,10S,10aS,10bS)-6a,10-dihydroxy-7,7,10a-trimethyl-4-oxo-3b,3b1,5a,6,6a,7,8,9,10,10a,10b,11-dodecahydro-4H-phenanthro[3,2-b:10,1-b'c']difuran-6-yl acetate;(+)-Bonducellpin D. Grades: >95%. CAS No. 197781-85-4. Molecular formula: C22H28O7. Mole weight: 404.45.
Borapetoside B
Borapetoside B is isolated from Tinospora. Uses: Hypoglycemic. Alternative Names: methyl (2S,4aS,6S,6aR,9R,10aS,10bS)-2-(furan-3-yl)-9-hydroxy-6a,10b-dimethyl-4-oxo-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-2H-benzo[f]isochromene-7-carboxylate. Grades: 95%. CAS No. 104901-05-5. Molecular formula: C27H36O12. Mole weight: 552.568.
Borapetoside E
Borapetoside E is isolated from Tinospora. Alternative Names: 1,4-Methano-2-benzoxepin-9-carboxylic acid, 5-[(2S)-2-(3-furanyl)-2-(β-D-glucopyranosyloxy)ethyl]-1,3,4,5,5a,6,7,9a-octahydro-5,9a-dimethyl-3-oxo-, methyl ester, (1S,4R,5S,5aS,9aR)-; Methyl (1S,2R,7S,8S,9R)-8-[(2S)-2-(3-furyl)-2-(β-D-glucopyranosyloxy)ethyl]-2,8-dimethyl-10-oxo-11-oxatricyclo[7.2.1.02,7]dodec-3-ene-3-carboxylate. Grades: 95%. CAS No. 151200-49-6. Molecular formula: C27H36O11. Mole weight: 536.57.
Borapetoside F
Borapetoside F is isolated from Tinospora. Alternative Names: 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 2-(3-furanyl)-6-(β-D-glucopyranosyloxy)-1,4,6,6a,9,10,10a,10b-octahydro-6a,10b-dimethyl-4-oxo-, methyl ester, rel-(2R,6R,6aS,10aR,10bR)-(+)-; 2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 2-(3-furanyl)-6-(β-D-glucopyranosyloxy)-1,4,6,6a,9,10,10a,10b-octahydro-6a,10b-dimethyl-4-oxo-, methyl ester, (2α,6β,6aβ,10aβ,10bα)-(+)-; rel-Methyl (2R,6R,6aS,10aR,10bR)-(+)-2-(3-furanyl)-6-(β-D-glucopyranosyloxy)-1,4,6,6a,9,10,10a,10b-octahydro-6a,10b-dimethyl-4-oxo-2H-naphtho[2,1-c]pyran-7-carboxylate. Grades: 95%. CAS No. 151200-50-9. Molecular formula: C27H34O11. Mole weight: 534.55.
Bortezomib Impurity (R,R-Isomer)
Bortezomib Impurity (R,R-Isomer) is a diastereomer of Bortezomib. Alternative Names: (1R,2R)-Bortezomib; B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid. Grades: 98% by HPLC. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.25.
Bortezomib USP Impurity G
Bortezomib USP Impurity G is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Alternative Names: (1S,2S)-Bortezomib; ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. Grades: 95%. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.243.
Bortezomib USP Related Compoud B
Bortezomib USP Related Compoud B is an impurity of the acclaimed drug Bortezomib, which is a drug tailored towards the affliction of multiple myeloma. Alternative Names: Bortezomib Amide Impurity; N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grades: 98% by HPLC. CAS No. 289472-80-6. Molecular formula: C14H14N4O2. Mole weight: 270.29.
Boswellic acid
α-Boswellic acid, a pentacyclic triterpene molecule, is isolated from the herbs of Boswellia carterii Birdw. Nutritional supplement in health care products. Uses: Ingredient of health care products. Alternative Names: (18β)-3α-Hydroxygermanica-12-ene-24-oic acid;(4R)-3α-Hydroxyolean-12-en-24-oic acid. Grades: 98%. CAS No. 471-66-9. Molecular formula: C30H48O3. Mole weight: 456.7.
BQU57
BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA. Alternative Names: BQU57; BQU 57; BQU-57. Grades: >98%. CAS No. 1637739-82-2. Molecular formula: C16H13F3N4O. Mole weight: 334.1.
BRD 4354
BRD 4354 is an HDAC5 and HDAC9 inhibitor (IC50 = 0.85 and 1.88 μM, respectively) displaying >20-fold selectivity for HDAC5/9 over HDAC1/2/3. It also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM). Alternative Names: BRD4354; BRD 4354; BRD-4354; 5-Chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-8-quinolinol. Grades: ≥98% by HPLC. CAS No. 315698-07-8. Molecular formula: C21H23ClN4O. Mole weight: 382.89.
BRD-6929
BRD-6929. CAS No. 849234-64-6.
Brequinar sodium
Brequinar sodium is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = ~20 nM), which causes the blockade of de novo pyrimidine nucleotide biosynthesis. Uses: Antineoplastic agents. Alternative Names: Dup785; Dup 785; Dup-785; Brequinar Sodium. 6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium; Dup 785. Grades: ≥99% by HPLC. CAS No. 96201-88-6. Molecular formula: C23H14F2NO2Na. Mole weight: 397.35.
Brevianamide F
Brevianamide F, belongs to a class of naturally occurring 2,5-diketopiperazines, is produced by the fungi A.fumigates and Aspergillus sp. Alternative Names: Cyclo-L-Trp-L-Pro; L-prolyl-L-tryptophan. Grades: ≥95%. CAS No. 38136-70-8. Molecular formula: C16H17N3O2. Mole weight: 283.33.
Brevilin A
Brevilin A, also called 6-O-Angeloylplenolina, is a natural sesquiterpenoid found in the herbs of Centipeda minima, it exhibits the antigiardial activity (IC50 = 16.1 μM) and is similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). Brevilin A inhibits janus kinase activity and exhibits both strong STAT3 signal inhibition and STAT3 signal dependent cell growth inhibition. Uses: Anti-giardial. Alternative Names: 6-O-Angeloylplenolin. Grades: >91%. CAS No. 16503-32-5. Molecular formula: C20H26O5. Mole weight: 346.4.
Brexpiprazole Impurity 10
Brexpiprazole Impurity 10 is an impurity of Brexpiprazole, a drug used to counter psychiatric afflictions such as schizophrenia and major depressive disorder. Alternative Names: m-Cinnamanisidide; N-(3-Methoxyphenyl)-3-phenylpropenamide. Grades: > 95%. CAS No. 15116-41-3. Molecular formula: C16H15NO2. Mole weight: 253.30.
Brimonidine EP Impurity A
Brimonidine EP Impurity A. CAS No. 91147-43-2.
Brimonidine EP Impurity F
Brimonidine EP Impurity F. CAS No. 151110-15-5.
Brinzolamide Related Compound B
Brinzolamide Related Compound B is Brinzolamide derivative. Alternative Names: (4R)-4-Amino-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide; AL 8520; N-Desethyl Brinzolamide. Grades: > 95%. CAS No. 404034-55-5. Molecular formula: C10H17N3O5S3. Mole weight: 355.46.