BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Alfadolone | Alfadolone, a synthetic steroid hormone, is an effective anti-inflammatory agent that relieves pain and inflammation associated with diseases like arthritis. Further, it is increasingly employed for treating autoimmune disorders like lupus and multiple sclerosis. The mechanism of action of alfadolone involves hampering the production of bodily chemicals responsible for inflammation. Alternative Names: Pregnane-11,20-dione, 3,21-dihydroxy-, (3alpha,5alpha)-. Grades: 95%. CAS No. 14107-37-0. Molecular formula: C21H32O4. Mole weight: 348.5. |  |
| Alimemazine-[d6] | Alimemazine-[d6] is a deuterium labelled Alimemazine, which is an antihistamine. Alternative Names: β-Methyl-(N,N-Dimethyl-d6)-10H-phenothiazine-10-propanamine Tartrate; 10-(2-Methyl-3-(dimethyl-d6)aminopropyl)phenothiazine Tartrate; 10-[3-[(Dimethyl-d6)amino]-2-methylpropyl]phenothiazine Tartrate; (+/-)-Alimemazine-d6 Tartrate; Panectyl-d6; Repeltin-d6; Temaril-d6; Temaril 16-d6; Theralene-d6; Vallergan-d6; Vanectyl-d6; NSC 17475-d6. Grades: >98%. CAS No. 1346603-88-0. Molecular formula: C18H16D6N2S. Mole weight: 304.48. | |
| Aliskiren hemifumarate | Aliskiren is a direct renin inhibitor used for the treatment of essential hypertension. Alternative Names: (αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeno-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonaoyl-2-methyl-propyl)-amide hemifumarate. Grades: 99%. CAS No. 173334-58-2. Molecular formula: C30H53N3O6·1/2C4H4O4. Mole weight: 1219.6. | |
| Alismoxide | The anti-inflammatory effects. Uses: Alismoxide has anti-inflammatory effects. Alternative Names: (1S,3aR,4R,8aS)-1,2,3,3a,4,5,6,8a-Octahydro-1,4-dimethyl-7-(1-methylethyl)-1,4-azulenediol. Grades: >98%. CAS No. 87701-68-6. Molecular formula: C15H26O2. Mole weight: 238.37. | |
| Alisol A | Alisol A is a natural product, which is extracteed from the tubers of Alisma plantago-aquatica Linn. Alternative Names: (23S,24R)-11b,23,24,25-Tetrahydroxydammar-13(17)-en-3-one; (8α,9β,14β,23S,24R)-11β,23,24,25-Tetrahydroxy-5α-dammar-13(17)-en-3-one. Grades: >98%. CAS No. 19885-10-0. Molecular formula: C30H50O5. | |
| Alisol A 24-acetate | Alisol A 24-acetate, a major active triterpenes isolated from a famous traditional chinese medicine called Rhizoma Alismatis, has been determined for the quality control of this crude drug. Alternative Names: [(3R,4S,6R)-2,4-dihydroxy-6-[(5R,8S,9S,10S,11S,14R)-11-hydroxy-4,4,8,10,14-pentamethyl-3-oxo-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] acetate alisol A 24-acetate Alisol A (24-acetate) 18674-16-3 24-O-Acetylalis. Grades: >98%. CAS No. 18674-16-3. Molecular formula: C32H52O6. Mole weight: 532.75. | |
| Alisol B | Alisol B, derived from a traditional Chinese medicine called Alisma orientale Juzepczuk, has strong inhibitory effects on osteoclast formation in vitro which has the potential to treat bone disorders. Alternative Names: (5R,8S,9S,10S,11S,14R)-17-[(2R,4S)-4-[(2R)-3,3-dimethyloxiran-2-yl]-4-hydroxybutan-2-yl]-11-hydroxy-4,4,8,10,14-pentamethyl-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one alisol B CHEBI:81104 18649-93-9. Grades: >98%. CAS No. 18649-93-9. Molecular formula: C30H48O4. Mole weight: 472.70. | |
| Alisol B 23-acetate | Alisol B acetate is a triterpene from Rhizoma Alismatis (rhizomes of Alisma plantago-aquatica). It induces apoptosis in human prostate cancer cells. It produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regul. Alternative Names: (23S,24R)-24,25-Epoxy-11b,23-dihydroxy-8a,9b,14b-dammar-13(17)-en-3-one 23-acetate;Alisol B 23-acetate;(8α,9β,14β,23S,24R)-11β-Hydroxy-23-acetoxy-24,25-epoxy-5α-dammara-13(17)-ene-3-one;23-Acetylalismol B;23-O-Acetylalisol B;Alisol B monoacetate. Grades: >98%. CAS No. 26575-95-1. Molecular formula: C32H50O5. Mole weight: 514.74. | |
| Alisol C 23-acetate | Alisol C 23-acetate is derived from the tubers of a traditional Chinese medicine Alisma plantago-aquatica Linn. Alternative Names: [(1S,3R)-1-[(2R)-3,3-dimethyloxiran-2-yl]-3-[(5R,8S,9S,10S,11S,14R)-11-hydroxy-4,4,8,10,14-pentamethyl-3,16-dioxo-2,5,6,7,9,11,12,15-octahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl] acetate Alisol C monoacetate Alisol C (23-acetate) 26575-93-9 23-Acetyl. Grades: >98%. CAS No. 26575-93-9. Molecular formula: C32H48O6. Mole weight: 528.72. | |
| Alisol F | Alisol F is a natural product, which is extracted from the tubers of Alisma plantago-aquatica Linn. It suppresses iNOS induction. Alternative Names: (8alpha,9beta,11beta,14beta,16beta,23S,24R)-16,23-Epoxy-11,24,25-trihydroxydammar-13(17)-en-3-one. Grades: >98%. CAS No. 155521-45-2. Molecular formula: C30H48O5. Mole weight: 488.70. | |
| Alisol F 24-acetate | Alisol F 24-acetate represents a naturally sourced product that may possess a broad range of bioactivities. This product has gained particular interest as a reference standard in Qianghuo studies, a traditional Chinese medicinal herb, acknowledged to exhibit anti-rheumatic, anti-cold, and anti-headache properties. Alisol F 24-acetate reveals promising anti-tumor capacities and demonstrates potential as a therapeutic approach for inflammatory conditions. Alternative Names: Alisol F 24-acetate;443683-76-9;CHEMBL3121590;BDBM50528863;AKOS032946078;HY-107315;CS-0027975;(24R)-24-acetoxy-11beta, 25-dihydroxy-16beta,23beta-epoxyprotost-13(17)-en-3-one;[(1R)-2-hydroxy-1-[(1S,2R,4S,6S,8R,12S,13S,14S,19R)-12-hydroxy-1,2,8,14,18,18-hexamethyl-17-oxo-5-oxapentacyclo[11.8.0.02,10.04,9.014,19]henicos-9-en-6-yl]-2-methylpropyl] acetate. Grades: >98%. CAS No. 443683-76-9. Molecular formula: C32H50O6. Mole weight: 530.74. | |
| Alisol G | Alisol G, a triterpenoid isolated from the rhizome of Alisma orientale, has hCE2 inhibitory effects. Alternative Names: (5R,8S,9S,10S,11S,14R)-17-[(2R,4S,5S)-4,5-dihydroxy-6-methylhept-6-en-2-yl]-11-hydroxy-4,4,8,10,14-pentamethyl-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one Alisol G 155521-46-3 CHEMBL3121588. Grades: >98%. CAS No. 155521-46-3. Molecular formula: C30H48O4. Mole weight: 472.71. | |
| Alizapride hydrochloride | Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Alternative Names: 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Hydrochloride; Limican; Nausilen; Plitican; Vergentan; N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-methoxy-1H-benzotriazole-6-carboxamide hydrochloride (1:1). Grades: >98%. CAS No. 59338-87-3. Molecular formula: C16H22ClN5O2. Mole weight: 351.83. | |
| ALK5 Inhibitor II hydrochloride | ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Alternative Names: E 616452; RepSox; SJN 2511. Grades: ≥98%. CAS No. 446859-33-2. Molecular formula: C17H13N5·HCl. Mole weight: 323.8. | |
| Allantoxanamide | Allantoxanamide was reported to be a novel inhibitor of uricase in vivo. Alternative Names: 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxamide; 4,6-dioxo-1H-1,3,5-triazine-2-carboxamide; 4-Hydroxy-6-oxo-1,6-dihydro-1,3,5-triazine-2-carboxamide. Grades: 95%. CAS No. 69391-08-8. Molecular formula: C4H4N4O3. Mole weight: 156.1. | |
| Alloc-Val-Ala-PAB-OH | Alloc-Val-Ala-PAB-OH is a peptide linker with a terminal Alloc protecting group. The peptide chain can act as a cleavable linker in drug design, such as in antibody drug conjugates (ADC). Alternative Names: Allyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide. CAS No. 1343407-91-9. Molecular formula: C19H27N3O5. Mole weight: 377.43. | |
| Allosecurinin | Allosecurinin is an alkaloid isolated from M.indica and M.discoidea. Alternative Names: Phyllochrysine; Allosecurinine; Virosecurinine. Grades: 0.98. CAS No. 884-68-4. Molecular formula: C13H15NO2. Mole weight: 217.26. | |
| Almorexant | Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1) / orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively. Uses: For research used only. Alternative Names: ACT-078573. Grades: 0.99. CAS No. 871224-64-5. Molecular formula: C29H31F3N2O3. Mole weight: 512.573. | |
| Almotriptan Malate | Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Uses: Serotonin receptor agonists. Alternative Names: LAS 31416; LAS31416; LAS-31416. Grades: >98%. CAS No. 181183-52-8. Molecular formula: C17H25N3O2S.C4H6O5. Mole weight: 469.55. | |
| Alnusone | Alnusone is a natural compound isolated from the barks of Alnus japonica. Grades: 97.5%. CAS No. 52330-11-7. Molecular formula: C19H18O3. Mole weight: 294.35. | |
| Alofanib | Alofanib, also known as RPT835, is a potent and selective allosteric inhibitor of FGFR2 with potential anticancer activity. Alofanib blocks the extracellular part of the receptor and prevents its binding with the ligand. Alternative Names: RPT835; RPT-835; RPT 835; Alofanib. Grades: 95%. CAS No. 1612888-66-0. Molecular formula: C19H15N3O6S. Mole weight: 413.404. | |
| Alogliptin | Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibiting greater than 10000-fold selectivity over DPP-8 and DPP-9. Alogliptin is used for the prevention of type 2 diabetes. Uses: Hypoglycemic agents. Alternative Names: (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitril. Grades:>98%. CAS No. 850649-61-5. Molecular formula: C18H21N5O2. Mole weight: 339.39. | |
| Aloperine | Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties. Aloperine induces apoptosis and autophagy in HL-60 cells. Uses: Anti-inflammatory, antibacterial, antiviral, and antitumor. Alternative Names: (6R,6aR,13S,13aS)-1,3,4,6,6a,7,8,9,10,12,13,13a-Dodecahydro-2H-6,13-methanodipyrido[1,2-a:3',2'-e]azocine; (7-alpha,9-alpha)-9-De-2-piperidinyl-16,17-didehydro-ormosanine; Ormosanine, 16,17-didehydro-9-de-2-piperidinyl-, (7-alpha,9-alpha)-; Allopterin; 6,13-Methano-2H-dipyrido[1,2-a:3',2'-e]azocine,1,3,4,6,6a,7,8,9,10,12,13,13a-dodecahydro-,[6R-(6α,6aβ,13α,13aα)]-. Grades: >98%. CAS No. 56293-29-9. Molecular formula: C15H24N2. Mole weight: 232.36. | |
| α,α,α',5-Tetramethyl-1, 3- benzenediacetonitril e | α,α,α',5-Tetramethyl-1, 3- benzenediacetonitril e is an intermediate in the synthesis of α-Desmethyl Anastrozole. Alternative Names: alpha1,alpha3,alpha3,5-Tetramethyl-1,3-benzenediacetonitrile. CAS No. 120512-38-1. Molecular formula: C14H16N2. Mole weight: 212.29. | |
| alpha,alpha-Dimethylbenzylamine | alpha,alpha-Dimethylbenzylamine (CAS# 585-32-0) is a reactant in the preparation of anti-malarial drugs. Also used in the preparation of HCV inhibitors. Alternative Names: 2-phenyl-2-propanamine; 2-phenylpropan-2-amine. CAS No. 585-32-0. Molecular formula: C9H13N. Mole weight: 135.21. | |
| α-calacorene | α-calacorene. CAS No. 21391-99-1. | |
| α-Epoxydihydroartemisinic acid | α-Epoxydihydroartemisinic acid isolated from the herbs of Artemisia annua L. Alternative Names: (2R)-2-[(1aR,3aS,4R,7R,7aS,7bS)-1a,4-Dimethyldecahydronaphtho[1,2 -b]oxiren-7-yl]propanoic acid. Grades: 98%. CAS No. 380487-65-0. Molecular formula: C15H24O3. Mole weight: 252.4. | |
| α-Glucosidase | α-Glucosidase. CAS No. 9001-42-7. | |
| α-Hydroxy Flurbiprofen | An impurity of Flurbiprofen. Flurbiprofen is a potent nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid derivative class (like ibuprofen). It exhibits analgesic, anti-inflammatory, and antipyretic effects by inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. Alternative Names: Flurbiprofen Impurity C; (2RS)-2-(2-Fluoro[1,1'-biphenyl]-4-yl)-2-hydroxypropanoic acid; (2RS)-2-(2-Fluorobiphenyl-4-yl)-2-hydroxypropanoic Acid; 2-(2-Fluorobiphenyl-4-yl)-2-hydroxypropanoic acid; 2-(2-Fluoro-[1,1'-biphenyl]-4-yl)-2-hydroxypropanoic acid; 2-Fluoro-α-hydroxy-α-methyl[1,1'-biphenyl]-4-acetic acid; 2-(2-Fluoro-4-biphenyl)-2-hydroxypropionic acid; Flurbiprofen EP Impurity C. Grades: >95%. CAS No. 61466-95-3. Molecular formula: C15H13FO3. Mole weight: 260.27. | |
| α-Lumicolchicine | α-Lumicolchicine. Alternative Names: (+)-α-Lumicolchicin; alpha-Lumicolchicine; Acetamide, N,N'-[(7S,7bR,8aS,8bS,9aR,10S,16cS,16dR,16eR,16fS)-5,6,7,7b,8,8a,8b,9,9a,10,11,12,16c,16d,16e,16f-hexadecahydro-1,2,3,8a,8b,14,15,16-octamethoxy-8,9-dioxobisbenzo[3',4']cyclohepta[1',2':3,4]cyclobuta[1,2-c:1',2'-c']cyclobuta[1,2-a:4,3-a']dicyclopentene-7,10-diyl]bis-. CAS No. 7183-82-6. Molecular formula: C44H50N2O12. Mole weight: 798.89. | |
| α-Obscurine | α-Obscurine is an alkaloid isolated from Lycopodium japonicum. Alternative Names: (1R,9S,10R,16R)-14,16-dimethyl-6,14-diazatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadec-2(7)-en-5-one. Grades: 98.0%. CAS No. 596-55-4. Molecular formula: C17H26N2O. Mole weight: 274.408. | |
| α-Santalol | α-Santalol. CAS No. 115-71-9. | |
| α-Viniferin | α-Viniferin isolated from the herb of Carex humilis Leyss. It inhibits AChE activity is specific, reversible and noncompetitive,down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages. Uses: Anti-inflammatory activity; antifungal; inhibits protein kinase c; inhibits prostaglandin h2 synthase carex humilis. Alternative Names: (+)-α-viniferin. Grades: 0.97. CAS No. 62218-13-7. Molecular formula: C42H30O9. Mole weight: 678.7. | |
| (αZ)-2-Amino-α-[(1-carboxy-1-methylethoxy)imino]-4-thiazoleacetic Acid | (αZ)-2-Amino-α-[(1-carboxy-1-methylethoxy)imino]-4-thiazoleacetic Acid can be used in the synthesis of Aztreonam, a synthetic monocyclic β-lactam antibiotic. Alternative Names: Aztreonam impurity 15. Grades: 95%. CAS No. 102507-85-7. Molecular formula: C9H11N3O5S. Mole weight: 273.26. | |
| Alpinetin | Alpinetin isolated from the fruits of Alpinia katsumadai. It has strong anti-hepatoma and pancreatic cancer cells effects, by inhibiting proliferation. Uses: Antibacterial activity; anti-inflammatory activity. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (2S)-; (2S)-2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (S)-; Flavanone, 7-hydroxy-5-methoxy-; (-)-Alpinetin; (S)-7-Hydroxy-5-methoxy-2-phenylchroman-4-one; 5-Methoxy-7-hydroxyflavanone; 5-O-Methylpinocembrin. Grades: ≥95%. CAS No. 36052-37-6. Molecular formula: C16H14O4. Mole weight: 270.28. | |
| Alpinumisoflavone | Alpinumisoflavone isolated from the herbs of Genista pichisermolliana. It maybe due to their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, Alpinumisoflavone has atheroprotective effects. Uses: Atheroprotective effects. Alternative Names: 5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one. Grades: 0.985. CAS No. 34086-50-5. Molecular formula: C20H16O5. Mole weight: 336.3. | |
| Alsterpaullone | Alsterpaullone is a potent glycogen synthase kinase-3 inhibitor and a potential therapeutic agent for the treatment of Parkinson disease. Alsterpaullone is also known as 9-Nitropaullone and NSC 705701, which is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Alsterpaullone induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Alsterpaullone is a derivative of kenpaullone with slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1 / cyclin B, Cdk2 / cyclin A, Cdk2 / cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Alternative Names: 9-Nitropaullone; NSC 705701; 7,12-Dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one. Grades: ≥98%. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.3. | |
| Alstolenine | Alstolenine is an alkaloid compound found in the Alstonia venenata. Alternative Names: Deacetylakuammiline trimethylgallate. Grades: >95%. CAS No. 85769-33-1. Molecular formula: C31H34N2O7. Mole weight: 546.6. | |
| Alstonic acid A | Alstonic acid A can be found in the herbs of Alstonia scholaris. Alternative Names: (3alpha,4beta)-3-(1,1-Dimethyl-2-oxoethyl)-4,8,9,20-tetramethyl-19-norpregn-5(10)-ene-4-acetic acid. Grades: >98%. CAS No. 1159579-44-8. Molecular formula: C30H48O3. Mole weight: 456.7. | |
| Alstonic acid B | Alstonic acid B is a natural compound isolated from the herbs of Alstonia scholaris. Alternative Names: Alstonic acid B; 1159579-45-9; 2-[(1R,4S,5R,8R,9R,12S,16R,19S)-4,9,12,17,17,19-hexamethyl-18-oxo-8-propan-2-yl-19-pentacyclo[14.2.1.01,13.04,12.05,9]nonadec-13-enyl]acetic acid; ZINC96023603; AKOS032962124. Grades: 98.0%. CAS No. 1159579-45-9. Molecular formula: C30H46O3. Mole weight: 454.695. | |
| Altiratinib | Altiratinib, also known as DCC-270, DP-5164, is an oral, selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Importantly, DCC-2701's anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF. DCC-2701 may be superior to HGF antagonists that are in clinical trials and that pTyr(1349) levels might be a good indicator of c-MET activation and likely response to targeted therapy as a result of signals from the microenvironment. Alternative Names: DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164; Altiratinib. Grades: >98%. CAS No. 1345847-93-9. Molecular formula: C26H21F3N4O4. Mole weight: 510.46. | |
| ALX-1393 | ALX-1393 is a selective glycine transporter GlyT2 inhibitor that has an antinociceptive effect on thermal, mechanical and chemical stimulation in rat models of acute pain. Alternative Names: (2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophenyl)methoxy)propanoic acid; O-[2-benzyloxyphenyl-3-flurophenyl]methyl-L-serine; L-Serine, O-[(3-fluorophenyl)[2-(phenylmethoxy)phenyl]methyl]-. Grades: ≥95%. CAS No. 949164-09-4. Molecular formula: C23H22FNO4. Mole weight: 395.42. | |
| AM095 | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Alternative Names: AM095 (free acid); AM-095; AM 095. Grades: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49. | |
| AM095 sodium | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Alternative Names: AM-095 sodium; AM 095 sodium. Grades: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48. | |
| AM580 | AM580 is a selective RARα agonist. It was shown to induce differentiation of human induced pluripotent stem cells into intermediate mesoderm. Alternative Names: AM-580; 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid. Grades: >98%. CAS No. 102121-60-8. Molecular formula: C22H25NO3. Mole weight: 351.44. | |
| Ambrisentan | Ambrisentan, a highly selective antagonist of the endothelin-1 type A receptor with IC50 of 18 nM, is indicated for the treatment of pulmonary arterial hypertension (PAH). Uses: Antihypertensive agents. Alternative Names: BSF-208075; BSF208075; BSF 208075; LU-208075; LU208075; LU 208075; Letairis; Volibris. Grades: >98%. CAS No. 177036-94-1. Molecular formula: C22H22N2O4. Mole weight: 378.42. | |
| Ambroxol EP Impurity C | An impurity of Ambroxol, a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. Alternative Names: trans-4-((2-Amino-3,5-dibromobenzylidene)amino)cyclohexanol; trans-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol; Cyclohexanol, 4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]-, trans-. Grades: ≥95%. CAS No. 50910-53-7. Molecular formula: C13H16Br2N2O. Mole weight: 376.09. | |
| Ambroxol Monobromine | An impurity of Ambroxol, a medication used in the treatment of respiratory diseases associated with viscid or excessive mucus. Alternative Names: trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol. Grades: > 95%. CAS No. 101900-43-0. Molecular formula: C13H19BrN2O. Mole weight: 299.21. | |
| Amcinonide | Amcinonide is a corticosteroid (IC50 = 3.38 nM) used as an anti-inflammatory and antipruritic agent. Uses: Anti-inflammatory agent. Alternative Names: cl-34699; cyclocort; Amciderm; Amcinonid; Penticort. Grades: ≥98%. CAS No. 51022-69-6. Molecular formula: C28H35FO7. Mole weight: 502.58. | |
| Amentoflavone | Amentoflavone, a natural flavonoid isolated from the the seed of Ginkgo biloba L, exhibits anti-inflammatory activity, and inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells. Amentoflavone has the inhibition of LPS-induced NO formation, due to its inhibition of NF-kappaB by blocking degradation, which may be the mechanistic basis of the anti-inflammatory effects of amentoflavone. Uses: Cytochrome p-450 cyp2c9 inhibitors. Alternative Names: 4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 3''',8-Biflavone, 4',4''',5,5'',7,7''-hexahydroxy-; 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Ginkgetin, didemethyl-; Amenthoflavone; I3',II8-Biapigenin; NSC 295677; Tridemethylsciadopitysin. Grades: >98%. CAS No. 1617-53-4. Molecular formula: C30H18O10. Mole weight: 538.46. | |
| Ametantrone | Ametantrone (AM) is a topoisomerase II inhibitor leading to covalent cross-links in DNA of tumor cells. It is a synthetic 9,10-anthracenedione containing two (hydroxyethylamino)ethylamino residues at positions 1 and 4. Along with other anthraquinones and anthracyclines, it shares a polycyclic intercalating moiety and charged side chains that stabilize DNA binding. Alternative Names: CI881; CI 881; CI-881; NSC196473; NSC 287513; NSC-196473; NSC 287513; 1,4-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione. CAS No. 64862-96-0. Molecular formula: C22H28N4O4. Mole weight: 412.49. | |
| Amfenac-[d5] Sodium Salt | Amfenac-[d5] Sodium Salt is a labelled sodium compound of Amfenac. Amfenac is a COX inhibitor with IC50 of 0.25 and 0.15 μM for COX-1 and COX-2, respectively. Alternative Names: 2-Amino-3-(benzoyl-d5)benzeneacetic Acid Sodium Salt. Grades: 95% by HPLC; 98% atom D. Molecular formula: C15H7D5NNaO3. Mole weight: 282.28. | |
| AMG-3969 | AMG-3969 is a potent and selective disruptor of glucokinase-glucokinase regulatory protein interaction (GK-GKRP). AMG-3969 can modulate the blood glucose levels in rodent models of diabetes. Alternative Names: 2-[4-[(2S)-4-(6-aminopyridin-3-yl)sulfonyl-2-prop-1-ynylpiperazin-1-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol. Grades: 98% by HPLC. CAS No. 1361224-53-4. Molecular formula: C21H20F6N4O3S. Mole weight: 522.466. | |
| AMG 925 | AMG-925 is a potent, selective, and bioavailable FLT3 / cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor. AMG 925 inhibited AML xenograft tumor growth by 96% to 99% without significant body weight loss. The antitumor activity of AMG 925 correlated with the inhibition of STAT5 and RB phosphorylation, the pharmacodynamic markers for inhibition of FLT3 and CDK4, respectively. In addition, AMG 925 was also found to inhibit FLT3 mutants (e.g., D835Y) that are resistant to the current FLT3 inhibitors (e.g., AC220 and sorafenib). AMG 925, which combines inhibition of two kinases essential for proliferation and survival of FLT3-mutated AML cells, may improve and prolong clinical responses. Alternative Names: AMG925; AMG-925; AMG 925; FLX925; FLX-925; FLX 925. Grades: >98%. CAS No. 1401033-86-0. Molecular formula: C26H29N7O2. Mole weight: 471.55. | |
| AMI-1 | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Alternative Names: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. Grades: ≥98%. CAS No. 20324-87-2. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. | |
| Amifostine Thiol-[d6] Dihydrochloride | Amifostine Thiol Dihydrochloride-[d6] is the isotope labelled analog of Amifostine Thiol Dihydrochloride, which is a metabolite of amifostine. Amifostine thiol activates p53 through a JNK-dependent signaling pathway. Alternative Names: 2-[(3-Aminopropyl)amino]ethanethiol Hydrochloride-d6; WR 1065-d6; Amifostine Thiol-d6 Dihydrochloride. Molecular formula: C5H8D6N2S.2HCl. Mole weight: 213.2. | |
| Amifostine Trihydrate | Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin. Alternative Names: Amifostine hydrate. Grades: >98%. CAS No. 112901-68-5. Molecular formula: C5H15N2O3PS.3H2O. Mole weight: 268.27. | |
| Amikacin EP Impurity I | Amikacin EP Impurity I. CAS No. 40371-51-5. | |
| Aminolevulinic acid phosphate | Aminolevulinic acid phosphate. CAS No. 868074-65-1. | |
| Aminomalononitrile p-toluenesulfonate | Aminomalononitrile p-toluenesulfonate (CAS# 5098-14-6) is a reagent for diazonamide synthesis via heck endocyclization. It may also have implications for developing IκB Kinase-β inhibitors. Alternative Names: 2-aminopropanedinitrile;4-methylbenzenesulfonic acid. Grades: 95 %. CAS No. 5098-14-6. Molecular formula: C10H11N3O3S. Mole weight: 253.28. | |
| (Aminomethyl)phosphonic acid | Aminomethanephosphonic acid is a degradation product of the herbicide glyphosate. Alternative Names: aminomethylphosphonic acid. Grades: 98 %. CAS No. 1066-51-9. Molecular formula: CH6NO3P. Mole weight: 111.04. | |
| Amitraz Related Compound B-[d3] | Amitraz Related Compound B-[d3]. Alternative Names: N-(2,4-Dimethyl-phenyl)-N'-methyl-D3-formamidine; Amitraz Metabolite-D3 BTS 27271; Amitraz Related Compound B-d3; N-(2,4-Dimethylphenyl)-N'-methylmethanimidamide-d3; BTS 27271-d3; Monoamitraz-d3. CAS No. 1255517-75-9. Molecular formula: C10H11D3N2. Mole weight: 165.25. | |
| Amlexanox | Amlexanox is a specific inhibitor of IKKε and TBK1, which inhibits IKKε and TBK1 activity as determined by MBP phosphorylation. Uses: Anti-allergic agents. Alternative Names: AA-673; AA673; AA 673; CHX 3673; CHX-3673; CHX3673; Amoxanox, Brand name: Aphthasol. Grades: >98%. CAS No. 68302-57-8. Molecular formula: C16H14N2O4. Mole weight: 298.29. | |
| Amlodipine EP impurity B | Amlodipine EP impurity B is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Alternative Names: N-[2-[(Methylamino)carbonyl]benzoyl] Amlodipine; 3-Ethyl 5-methyl (4RS)-4-(2-chlorophenyl)-6-methyl-2-[[2-[[2-(methylcarbamoyl)benzoyl]amino]ethoxy]methyl]-1,4-dihydropyridine-3,5-dicarboxylate. Grades: >95%. CAS No. 721958-72-1. Molecular formula: C29H32ClN3O7. Mole weight: 570.03. | |
| Amlodipine EP Impurity D Oxalate | Amlodipine EP Impurity D Oxalate is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Alternative Names: 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester Oxalate; Dehydro Amlodipine Oxalate; Amlodipine USP Related Compound A; 3-Ethyl 5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate oxalate salt. Grades: >95%. CAS No. 1216406-90-4. Molecular formula: C20H23ClN2O5.C2H2O4. Mole weight: 496.89. | |
| Amlodipine EP impurity G | Amlodipine EP impurity G is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Alternative Names: Amlodipine USP Related Compound C; 4-(2-Chlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester; 4-(2-Chlorophenyl)-3,5-di(methoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine. Grades: >95%. CAS No. 43067-01-2. Molecular formula: C17H18ClNO4. Mole weight: 335.78. | |
| Amonafide | Amonafide is an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis. Uses: Antineoplastic agents. Alternative Names: Nafidimide; Quinamed; Xanafide. Grades: 0.98. CAS No. 69408-81-7. Molecular formula: C16H17N3O2. Mole weight: 283.33. | |
| Amorolfine hydrochloride | Amorolfine hydrochloride is an antifungal agent used for the treatment of fungal infections of the fingernails and toenails. Alternative Names: KWD 2019; KWD2019; KWD-2019. Grades: >98%. CAS No. 78613-38-4. Molecular formula: C21H36ClNO. Mole weight: 353.97. | |
| Amoxicillin Dimer Impurity | An impuroty of Amoxicillin, a β-lactam antibiotic in the aminopenicillin family used to treat bacterial infections caused by susceptible Gram-positive and Gram-negative microorganisms. Alternative Names: Amoxicillin Dimer (penicilloic acid form). CAS No. 210289-72-8. Molecular formula: C32H40N6O11S2. Mole weight: 748.82. | |
| Amoxicillin EP Impurity G | Amoxicillin EP Impurity G. CAS No. 188112-75-6. | |
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