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5-Propargylamino-ddUTP - ATTO-Rho11
5-Propargylamino-ddUTP - ATTO-Rho11, a fluorescent nucleotide analog, serves as an excellent label for DNA strands during a multitude of molecular biology techniques, including polymerase chain reactions (PCR). Its exceptional specificity and sensitivity for nucleic acids render it an indispensable component for in situ hybridization and imaging studies. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with ATTO Rho11, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H55N6O16P3 (free acid). Mole weight: 1052.29 (free acid).
5-Propargylamino-ddUTP - ATTO-Rho12
5-Propargylamino-ddUTP - ATTO-Rho12 is an extraordinary nucleotide analogue, finding application in the realm of biomedical research owing to its exceptional fluorescent labeling and detection capabilities targeted towards specific DNA sequences. This innovative compound lends itself to facile integration into DNA via enzymatic research and development or PCR, offering a unique visual representation and measurable assessment of DNA fragments. With its remarkable fluorescent signal intensity and unrivaled photo-stability, it emerges as an ideal candidate for an assortment of cutting-edge applications encompassing DNA sequencing, gene expression analysis and in situ hybridization. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with ATTO Rho12, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H67N6O16P3 (free acid). Mole weight: 1136.38 (free acid).
5-Propargylamino-ddUTP - ATTO-Rho13
5-Propargylamino-ddUTP - ATTO-Rho13, a fluorescent nucleotide analog, is commonly utilized in DNA sequencing and analysis applications, enabling observation and scrutiny of DNA replication, transcription, and repair procedures via its integration into DNA strands. This product's frequent employment comprises co-utilization with other fluorescent nucleotide analogs for multiplex sequencing and investigation. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with ATTO Rho13, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H63N6O16P3 (free acid). Mole weight: 1132.35 (free acid).
5-Propargylamino-ddUTP - ATTO-Rho14
5-Propargylamino-ddUTP - ATTO-Rho14 serves as a valuable fluorescent nucleotide analog, which is crucial for the detection and labeling of DNA in biomedical research. Consistent with its primary role, it is frequently applied to label DNA either during PCR amplification or DNA synthesis. With the advent of ATTO-Rho14, the processes of DNA replication, transcription, and repair can be studied with specificity and sensitivity. Given its fluorescent signal, this product is an asset to those who seek to understand DNA mechanisms and advance in drug discovery as well as various disease diagnoses. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with ATTO Rho14, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H59Cl4N6O16P3 (free acid). Mole weight: 1268.20 (free acid).
5-Propargylamino-ddUTP - ATTO-Rho6G
5-Propargylamino-ddUTP is a modified form of deoxyuridine triphosphate (dUTP) used in the biomedical industry as a substrate for DNA polymerases. It is often used in combination with fluorescent dyes, such as ATTO-Rho6G, for labeling and imaging DNA in assays. This product is commonly used in research related to cancer, genetic disorders, and viral infections. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with ATTO Rho6G, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H51N6O16P3 (free acid). Mole weight: 1000.26 (free acid).
5-Propargylamino-ddUTP - ATTO-Thio12
5-Propargylamino-ddUTP - ATTO-Thio12 is a unique compound widely used in the biomedical industry for labeling and detecting specific DNA sequences. It serves as a fluorescent nucleotide analogue that can be incorporated into DNA during synthesis and helps in the detection of DNA damage or replication errors in various diseases like cancer. Its high sensitivity and specificity make it a valuable tool in numerous genetic and diagnostic research applications. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with ATTO Thio12, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H47N6O15P3S (free acid). Mole weight: 988.83 (free acid).
5-Propargylamino-ddUTP - Cy3
5-Propargylamino-ddUTP - Cy3 is a nucleotide analog with fluorescent properties that are highly beneficial for visualizing DNA both in vitro and in vivo. Its detection range enables scientists to study a vast array of DNA-related phenomena, including damage, replication, repair, cellular differentiation, and nuclear dynamics. Incorporation during synthesis is straightforward, and the product is designed for maximum convenience and efficacy. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H54N5O20P3S2 (free acid). Mole weight: 1117.96 (free acid).
5-Propargylamino-ddUTP - Cy5
5-Propargylamino-ddUTP - Cy5, known for its fluorescent dye-labeled nucleotide analog, serves as a critical tool for biomedical researchers in detecting gene mutations linked to diseases such as cancer. In doing so, the innovative dye provides the ability to visualize the location of such mutations on the genome, lending insight into their impact on disease development and progression. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H56N5O20P3S2 (free acid). Mole weight: 1144.00 (free acid).
5-Propargylamino-ddUTP - DY-480XL
5-Propargylamino-ddUTP - DY-480XL, a modified nucleotide utilized to sequence DNA in the biochemical industry, is renowned for its ability to detect and label DNA damage and repair. Interestingly, it is also widely used as a substrate for terminal deoxynucleotidyl transferase, enabling precise detection of leukemia and lymphoma. Its exceptional properties make it an invaluable tool in any laboratory performing DNA sequencing. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DY 480XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H46N5O19P3S (free acid). Mole weight: 1001.78 (free acid).
5-Propargylamino-ddUTP - DY-485XL
5-Propargylamino-ddUTP is a nucleotide analog used in biomedicine research for selective labeling of DNA polymerase synthesized DNA. It can be incorporated into nascent DNA strands during PCR amplification or as a substrate for terminal deoxynucleotidyl transferase (TdT) mediated 3 end labeling. The labeling can be visualized by fluorescent dyes such as DY-485XL. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DY 485XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H46N5O19P3S (free acid). Mole weight: 989.77 (free acid).
5-Propargylamino-ddUTP - DY-751
5-Propargylamino-ddUTP - DY-751 is an extensively employed nucleotide analog in the realm of compound research, providing insights into the perplexing facets of DNA labeling during sequencing or PCR methodologies. Functioning as a substrate for DNA polymerases, 5-Propargylamino-ddUTP diligently competes by inhibiting their activity. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DY 751, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C54H68N5O21P3S2 (free acid). Mole weight: 1279.31 (free acid).
5-Propargylamino-ddUTP - DY-776
5-Propargylamino-ddUTP - DY-776, a nucleotide analogue, is an exceptional tool enabling DNA labeling amid DNA synthesis and replication. In particular, this product is undoubtedly a vital instrument for scrutinizing intricated facets of DNA damage and repair pathways within cancer research. Moreover, it holds the key to illuminating nuances in the identification of replicating cells that simply cannot be observed otherwise. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DY 776, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C56H64N5O21P3S2 (free acid). Mole weight: 1300.18 (free acid).
5-Propargylamino-ddUTP - DYQ-660
5-Propargylamino-ddUTP, a nucleoside analogue incorporated into DNA during synthesis, is a versatile substrate for DNA polymerase enzymes, affording researchers robust tools to study replication dynamics. Wielding unique structural differences compared to traditional analogues, 5-Propargylamino-ddUTP also proves pivotal in antiviral and anticancer drug development, showcasing the potential of cutting-edge biomedical technology in the fight against disease. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C51H60N5O18P3S (free acid). Mole weight: 1156.04 (free acid).
5-Propargylamino-ddUTP - DYQ-661
5-Propargylamino-ddUTP is a nucleotide analog used in biomedical research to label DNA during synthesis. It can be incorporated into DNA by polymerases and detected using copper-catalyzed azide-alkyne cycloaddition (CuAAC) chemistry. This technique allows for precise visualization and measurement of DNA synthesis in various disease models, including cancer and neurological disorders. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with DYQ 661, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C51H59N5O21P3S2 (Anion). Mole weight: 1235.09 (Anion).
5-Propargylamino-ddUTP - MANT
5-Propargylamino-ddUTP - MANT, a modified nucleotide which finds application in nucleic acid detection and labeling, presents a potential avenue for studying DNA polymerase with utmost precision. Furthermore, it is specifically devised for RNA labeling utilizing click chemistry and fluorescence-based detection. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H25N4O14P3 (free acid). Mole weight: 638.35 (free acid).
5-Propargylamino-ddUTP - OYSTER-656
5-Propargylamino-ddUTP, a nucleoside analog employed in biomedicine, serves as a vital tool for exploring nucleic acid synthesis as well as repair mechanisms. During replication, it can seamlessly integrate into DNA or RNA, making it an important element in various studies encompassing viral infections, cancer, and genetic disorders. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H18N3O13P3- OYSTER 656 (free acid). Mole weight: 1221.18 (free acid).
5-Propargylamino-ddUTP - Texas Red
5-Propargylamino-ddUTP - Texas Red imbues a luminescent brilliance to DNA through its application as a fluorescent nucleotide derivative in DNA labeling. Employing it during PCR amplification permits the detection and imaging of recently synthesized DNA. An incredibly versatile tool, it finds particular significance in situations such as cancer research, gene expression analysis, and diagnostics. Alternative Names: 5-Propargylamino-2',3'-dideoxyuridine-5'-triphosphate, labeled with Texas Red, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C49H57N6O20P3S2 (free acid). Mole weight: 1207.06 (free acid).
5-Propargyloxy-dU CEP
5-Propargyloxy-dU CEP is a vital compound in biomedicine, commonly used to develop nucleotide analogues for antiviral or anticancer drugs. With its unique properties, it facilitates the synthesis of modified DNA molecules that specifically target and inhibit viral replication or cancer cell growth. CAS No. 1311144-61-2. Molecular formula: C42H49N4O9P. Mole weight: 784.83.
5-Propynyl-2'-deoxycytidine
5-Propynyl-2'-deoxycytidine is a nucleoside analog that has demonstrated antitumor activity against a variety of cancers, including leukemia, breast cancer, and lung cancer. It acts by inhibiting DNA synthesis, leading to apoptosis in cancer cells. It has also been shown to enhance the efficacy of other chemotherapeutic agents when used in combination therapy. Grades: ≥ 98% by HPLC. Molecular formula: C12H15N3O4. Mole weight: 265.27.
5-Propynyl-2'-deoxycytidine-5'-Triphosphate
5-Propynyl-2'-deoxycytidine-5'-Triphosphate is a vital tool in compound used for various applications. It functions as a chain terminator during DNA research and development, specifically targeting cancer cells. This compound is commonly used in the development of anticancer drugs and research focused on understanding and studying hematological malignancies. Alternative Names: 5-Propynyl-dCTP; 5-(1-Propynyl)-2'-deoxycytidine 5'-triphosphoric acid. Grades: ≥90% by AX-HPLC. Molecular formula: C12H18N3O13P3. Mole weight: 505.20.
5-Propynyl-2'-deoxyuridine
5-Propynyl-2'-deoxyuridine is an exceptionally potent antiviral compound, exhibiting commendable efficacy as a DNA enhancement inhibitor. Its profound impact lies in its ability to impede viral DNA replication. Grades: ≥ 98% by HPLC. Molecular formula: C12H14N2O5. Mole weight: 266.25.
5-Propynyl-2'-deoxyuridine-5'-Triphosphate
5-Propynyl-2'-deoxyuridine-5'-Triphosphate - a powerful and versatile nucleoside analogue that integrates into DNA during replication, impeding viral DNA polymerase and bringing about chain termination. Its broad-spectrum antiviral qualities have made it a primary focus for treating viral infections, including herpes simplex and varicella zoster viruses. Alternative Names: 5-Propynyl-dUTP; alpha-Ethylidynethymidine 5'-triphosphoric acid. Grades: ≥90% by AX-HPLC. Molecular formula: C12H17N2O14P3. Mole weight: 506.10.
5-Propynyl-cytidine
5-Propynyl-cytidine, a nucleoside analog with antitumor and antiviral properties, is used to inhibit RNA synthesis in certain viruses. Studies demonstrate its efficacy in treating hepatocellular carcinoma and pancreatic cancer. In addition, its ability to selectively target cancerous cells while sparing healthy ones, provides a promising avenue for future cancer treatments. Grades: ≥ 98% by HPLC. Molecular formula: C12H15N3O5. Mole weight: 281.26.
5-Propynyl-uridine
5-Propynyl-uridine, a nucleoside analog known for its antiviral effects against hepatitis C virus, has demonstrated potential as an anticancer agent. Its mechanism of action as an RNA replication inhibitor is just one of its characteristics which may contribute to its ability to induce apoptosis and suppress proliferation of cancer cells; however, further studies are necessary to fully investigate its potential as a therapeutic agent. Grades: ≥ 98% by HPLC. Molecular formula: C12H14N2O6. Mole weight: 282.25.
5'-PuMP
5'-PuMP is a potent, competitive inhibitor that regulates enzymes. It can interact with adenosine-5'-monophosphate. Alternative Names: Purine riboside- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 13484-60-1. Molecular formula: C10H13N4O7P (free acid). Mole weight: 332.2 (free acid).
5'-Pyrene Cap Phosphoramidite
5'-Pyrene Cap Phosphoramidite is a molecule used in the field of biomedicine as a reagent during oligonucleotide synthesis. It is commonly used to introduce fluorescence properties into nucleic acid molecules for use in various diagnostic techniques and imaging studies. Additionally, this product may be used to develop new drugs for the treatment of cancer, viral diseases, and other genetic-based conditions. Alternative Names: (N-(1-pyrenylmethyl)-pyrrolidin-3-oxy)-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C30H36N3O2P. Mole weight: 501.60.
5-Pyrrolidinomethyluridine
5-Pyrrolidinomethyluridine is an influential compound, showcasing its remarkable potential in the research of diverse ailments such as Alzheimer's and Parkinson's disease, primarily focusing on neurological disorders. Alternative Names: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(pyrrolidin-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione; Uridine, 5-(1-pyrrolidinylmethyl)-; 5-(1-Pyrrolidinylmethyl)uridine. Grades: ≥95%. CAS No. 1613530-41-8. Molecular formula: C14H21N3O6. Mole weight: 327.33.
5'-QD-1 CE Phosphoramidite
5'-QD-1 CE Phosphoramidite, a vital pharmaceutical product in biomedicine and molecular biology research, is an exceptional building block that guarantees high-purity oligonucleotide synthesis, enriched with fluorescent labelling capabilities for the thorough detection of genetic diseases and mutations. With its extraordinary stability, this remarkable tool fuses chemical innovation and cutting-edge science - a force to be reckoned with in modern gene therapy. Grades: >95% by HPLC. Molecular formula: C34H45N8O5P. Mole weight: 676.75.
5'-QD-2 CE Phosphoramidite
5-QD-2 CE Phosphoramidite, a crucial biomedicine product of the nucleotide-based therapeutic field, stands as an unparalleled aid in the modification of oligonucleotides, especially antisense oligonucleotides and siRNAs. With its enhanced stability and efficacy, the biomedical industry holds it in high esteem, treating it as an essential ingredient for targeted disease treatment research. Grades: >95% by HPLC. Molecular formula: C33H43N8O6P. Mole weight: 678.73.
5-(R-2-Phenyl-pyrrolidine)-1-yl-5-deoxy-1,2-isopropylidene-a-D-xylofuranose is a biomedical compound with anticancer attributes origining from its adept interaction with specific receptors, effectively impeding neoplasmic cells developments. Moreover, its antiviral has efficacy proven exceptional, diligently thwartingviral replication and minimizes viral burden. Molecular formula: C18H25NO4. Mole weight: 319.40.
5-(R-2-Pyridin-3-yl-pyrrolidine)-1-yl-5-deoxy-1,2-isopropylidene-α-D-xylofuranose is a cutting-edge biocompound, exhibiting unparalleled innovation in research of multifarious ailments encompassing cancer, diabetes and infectious diseases. Leveraging its distinctive molecular framework, it selectively antagonizes vital enzymes and receptors implicated in pathological pathways. Molecular formula: C17H24N2O4. Mole weight: 320.39.
5'-(R)-C-Methyl-2-thiouridine
5'-(R)-C-Methyl-2-thiouridine, a nucleoside derivative widely explored within the biomedical domain, emerges as an intriguing candidate endowed with antiviral prowess. Elucidating its intricate mechanisms of action renders this compound an invaluable asset in the realm of pioneering antiviral therapeutics. Alternative Names: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((R)-1-hydroxyethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one. Molecular formula: C10H14N2O5S. Mole weight: 274.29.
5'(R)-C-Methyl-2-thiouridine
5'(R)-C-Methyl-2-thiouridine is an exceptionally potent and impactful compound, holding remarkable potential in studying an array of notorious RNA viruses including dengue, yellow fever, and hepatitis C. The mechanism of its action lies in its exquisite ability to impede viral RNA synthesis. Alternative Names: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-((R)-1-hydroxyethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one. Grades: ≥95%. CAS No. 2305416-01-5. Molecular formula: C10H14N2O5S. Mole weight: 274.29.
5'(R)-C-Methyl-3-deazauridine
5'(R)-C-Methyl-3-deazauridine, a formidable antiviral and anticancer compound widely applied in the biomedical sector, exerts remarkable inhibitory effects on RNA virus proliferation. Its efficacy extends to combating herpes simplex and hepatitis C viruses. Alternative Names: 4-Hydroxy-1-(5(R)-C-methyl)-beta-D-ribofuranosyl-2(1H)-pyridinone. Grades: ≥95%. CAS No. 2305415-82-9. Molecular formula: C11H15NO6. Mole weight: 257.24.
5'(R)-C-Methyl-5-fluorouridine
5'(R)-C-Methyl-5-fluorouridine is an impactful antiviral nucleoside analog extensively utilized within the biomedical realm, showcasing remarkable selectivity in its cytotoxicity towards specific cancer cells. Its pivotal role lies in research of diverse viral infections, exemplified by its utilization in hepatitis C. This remarkable compound impeccably assumes the capacity of a nucleoside reverse transcriptase inhibitor, effectively hindering viral replication and, thereby, facilitating the mitigating of viral ailments. Alternative Names: 5'-C-Methyl-5-fluorouridine. Grades: ≥95%. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5'(R)-C-Methyl-5-methyluridine
5'(R)-C-Methyl-5-methyluridine - an essential constituent in the biomedicine sector, precisely utilized for the advancement of antiviral medications. Demonstrating remarkable effectiveness against RNA viruses, it presents substantial value in combating viral infections. Its exceptional molecular configuration holds immense therapeutic promise, signifying a gateway for extensive examination and propitious advancements in antiviral therapeutics. Alternative Names: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione. Grades: ≥95%. CAS No. 129745-35-3. Molecular formula: C11H16N2O6. Mole weight: 272.25.
5'(R)-C-Methylcytidine
5'(R)-C-Methylcytidine is a prominent pharmaceutical compound utilized in the compound sector, playing a crucial role in research of viral infections, especially those affecting the respiratory system. By effectively impeding viral replication, this compound emerges as a formidable force in diminishing the infection's intensity and duration. With its distinctive configuration and intricate mode of operation, it becomes an auspicious contender in the realm of antiviral drug development. Alternative Names: 4-Amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-((R)-1-hydroxy-ethyl)-tetrahydro-furan-2-yl]-1H-pyrimidin-2-one; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]pyrimidin-2-one; 1-(6-deoxy-β-D-allofuranosyl)cytosine. Grades: ≥95%. CAS No. 72159-53-6. Molecular formula: C10H15N3O5. Mole weight: 257.24.
5'(R)-C-Methyl-N6-methyladenosine
5'(R)-C-Methyl-N6-methyladenosine is a profound biomedical compound widely employed in research investigations, serving as an exquisite analog of the indigenous RNA alteration known as N6-methyladenosine (m6A). Notably, this intriguing modification materializes as a pivotal player within epitranscriptomics. Remarkably, this chemically enhanced nucleoside pioneers the unveiling of profound insights into the intricate interplay between RNA methylation, gene expression, transcript stability is and RNA-protein interactions. Grades: ≥95%. Molecular formula: C12H17N5O4. Mole weight: 295.29.
5'(R)-C-Methyluridine
5'(R)-C-Methyluridine is an essential biomedical compound, serving as an indispensable weapon in research of viral infections and cancer. Its remarkable antiviral properties enable the effective suppression of RNA-based viruses such as hepatitis and HIV. Moreover, by actively participating in the intricate process of RNA and DNA research and development, this compound greatly aids in unraveling the complexities of genetic diseases. Alternative Names: 1-(6-Deoxy-b-D-allofuranosyl)-2,4(1H,3H)pyrimidinedione; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-((R)-1-hydroxy-ethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione; 1-(6-deoxy-β-D-allofuranosyl)uracil; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 72159-54-7. Molecular formula: C10H14N2O6. Mole weight: 258.23.
5'(R)-Me-T amidite
5'-O-DMTr-5'(R)-C-methyl-thymidine 3'-CED phosphoramidite is a modified phosphoramidite used in DNA synthesis. It is particularly useful for synthesizing DNA oligonucleotides with enhanced stability and resistance to degradation. It can be employed in molecular biology, diagnostics, and therapeutic applications where modified DNA sequences are needed for specific functions, such as gene editing, diagnostics, or drug development. Alternative Names: 5'-O-DMTr-5'(R)-C-methyl-thymidine 3'-CED phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,6-dideoxy-β-D-ribo-hexofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5'(R)-Me-dT amidite. Grades: ≥97%. CAS No. 167934-48-7. Molecular formula: C41H51N4O8P. Mole weight: 758.84.
5-(S-2-Phenyl-pyrrolidine)-1-yl-5-deoxy-1,2-isopropylidene-a-D-xylofuranose is an invaluable compound of profound significance, facilitating the research of potential remedies that target precise proteins or receptors linked to afflictions encompassing cancer, inflammation, and neurological maladies. Molecular formula: C18H25NO4. Mole weight: 319.40.
5-(S-2-Pyridin-3-yl-pyrrolidine)-1-yl-5-deoxy-1,2-isopropylidene-a-D-xylofuranose is an intriguing biomedical tool with promising potential in research of targeting intricate drug receptors and enzymes that partake in menacing ailments such as cancer, neurological disorders and metabolic syndromes. CAS No. 957505-59-8. Molecular formula: C17H24N2O4. Mole weight: 320.39.
5'-S-[3-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]-2',3'-O-(1-methylethylidene)-5'-thio-adenosine is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt, a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Alternative Names: 2-(3-((((3aS,4S,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)thio)propyl)isoindoline-1,3-dione. CAS No. 263715-50-0. Molecular formula: C24H26N6O5S. Mole weight: 510.57.
5'-S-(3-Aminopropyl)-5'-thio-adenosine Sulfate
5'-S-(3-Aminopropyl)-5'-thio-adenosine Sulfate is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt, a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Alternative Names: (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminopropyl)thio)methyl)tetrahydrofuran-3,4-diol Sulfate. CAS No. 99019-00-8. Molecular formula: C13H20N6O3S H2SO4. Mole weight: 340.41.
5'(S)-Me-T amidite
5'(S)-Me-T amidite is a modified phosphoramidite used in DNA synthesis. It is particularly useful for synthesizing DNA oligonucleotides with enhanced stability and resistance to degradation. It can be employed in molecular biology, diagnostics, and therapeutic applications where modified DNA sequences are needed for specific functions, such as gene editing, diagnostics, or drug development. Alternative Names: 5'-O-DMTr-5'(S)-C-methyl-thymidine 3'-CED phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,6-dideoxy-α-L-lyxo-hexofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5'(S)-Me-dT amidite. Grades: ≥97%. CAS No. 167934-49-8. Molecular formula: C41H51N4O8P. Mole weight: 758.84.
5-S-Methyl-5-thio-D-xylose
5-S-Methyl-5-thio-D-xylose is a highly potent and dynamic compound intricately modulating viral replication and impeding cancer progression through exquisite precision. It emerges as a formidable anti-viral and anti-neoplastic agent. Alternative Names: D-Xylose, 5-S-methyl-5-thio-. CAS No. 53458-58-5. Molecular formula: C6H12O4S. Mole weight: 180.22.
5-(t-Butyldimethyldilyoxymethyl)-2'-deoxycytidine
5-(t-Butyldimethyldilyoxymethyl)-2'-deoxycytidine is a nucleoside analog, which is a synthetic molecule that resembles natural nucleosides found in DNA. Nucleoside analogs are often used in medical and biological research due to their ability to interact with nucleic acids and enzymes involved in DNA and RNA metabolism. This specific compound has been identified as a human endogenous metabolite, which means it is naturally produced within the human body. Alternative Names: 5-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-2'-deoxycytidine; 5-OTBS-CH2-2'-deoxycytidine. Molecular formula: C16H29N3O5Si. Mole weight: 371.51.
5-(t-Butyloxycarbonylmethoxy)uridine
5-(t-Butyloxycarbonylmethoxy)uridine, a remarkable and highly effective anti-viral agent, finds extensive utilization in medical practices targeting severe viral diseases such as hepatitis B and C. Its mechanism of action involves the inhibition of viral RNA replication, thereby exerting a suppressive influence on viral proliferation. Grades: ≥95%. Molecular formula: C15H22N2O9. Mole weight: 374.34.
5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine
5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine, a modified guanosine, is a pivotal compound in biomedical research, facilitating DNA synthesis. It provides an ideal substrate for DNA polymerases while also being a key ingredient in nucleic acids chemistry, useful in exploring the relationship between DNA damage and cancer. Additionally, its application as a tool to focus on the structure-function links of DNA-repair enzymes has been extensive, unveiling novel research opportunities. Alternative Names: 5'-O-TBDMS-2'-deoxyguanosine; 2-Amino-9-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 5'-O-TBDMS-dG; 2'-Deoxy-5'-O-[dimethyl(2-methyl-2-propanyl)silyl]guanosine. Grades: ≥97% by HPLC. CAS No. 51549-33-8. Molecular formula: C16H27N5O4Si. Mole weight: 381.51.
5'-tert-butyldimethylsilyloxy-N4-acetyl-5-iodo-cytidine, a pharmaceutical intermediate renowned for its antiviral properties, is widely employed in the production of antiviral drugs. Its efficacy has been empirically proven against herpes simplex virus, cytomegalovirus, and varicella-zoster virus. Additionally, this product serves as a potent weapon in the biomedical industry's battle against numerous other viral infections that threaten public health. Alternative Names: 5'-O-TBDMS-N4-acetyl-5-iodo-cytidine. Grades: ≥97% by HPLC. Molecular formula: C17H28IN3O6Si. Mole weight: 525.42.
5'-Tetrachloro-Fluorescein CE Phosphoramidite(6-TET)
5'-Tetrachloro-Fluorescein CE Phosphoramidite (6-TET) is an exceptional nucleoside derivatizing reagent. Significantly, its high sensitivity and specificity are beneficial for the fluorescence-based detection methods when examining single nucleotide polymorphisms, gene expression, or DNA sequencing. Moreover, novel investigations show that it could be imperative when studying mitochondrial DNA damages commonly implicated in both cancer and neurological disorders. Alternative Names: 6-[(4,7,2',7'-Tetrachloro-3',6'-dipivaloylfluoresceinyl)-carboxamido]-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: >97% by HPLC. Molecular formula: C46H54CI4N3O10P. Mole weight: 981.73.
5-TFA-aha-2'-Deoxycytidine
5-TFA-aha-2'-Deoxycytidine, a synthetic nucleoside analog with potential therapeutic properties against multiple cancer types including breast, lung, and pancreatic cancer, works by incorporating into the DNA strands of cancer cells resulting in the inhibition of cellular replication and ultimately, cell death. Its effective application in combatting cancer renders it an intriguing area of study towards developing novel cancer treatments. Alternative Names: TFA-aha-dC; 5-TFA-aha-dC. Grades: ≥98% by HPLC. Molecular formula: C20H28F3N5O6. Mole weight: 491.46.
5-Thio-a-D-mannose
5-Thio-a-D-mannose is a crucial entity in compound commonly harnessed for erecting intricate chemical frameworks and concocting bespoke medications exhibiting a multifaceted functionality encompassing the amelioration of specific infections and augmentation of drug potency. Alternative Names: 5-Thio-alpha-D-mannopyranose. CAS No. 127854-51-7. Molecular formula: C6H12O5S. Mole weight: 196.22.
5-Thio-D-glucose-6-phosphate diammonium salt, an indispensable entity within the biomedical sphere, finds its purpose primarily in the exploration and advancement of glucose metabolism. This remarkable substance assumes a crucial stance in the investigation of diverse ailments, encompassing diabetes, metabolic irregularities, and cystic fibrosis. Ascertaining its worth lies in enabling the scientific community to delve into the intricate biochemical pathways intertwined with glucose and its derivatives, empowering their profound understanding. CAS No. 108391-99-7. Molecular formula: C6H19N2O8PS. Mole weight: 310.26.
5-Thio-L-fucose
5-Thio-L-fucose, a sugar derivative with rare properties, has shown potential as an anti-tumor agent. Its unique ability to impede tumor proliferation and trigger programmed cell death in cancerous cells makes it a promising candidate for drug development. Research suggests its effectiveness in combating breast and colon cancers among others. Alternative Names: 5-thio-l-fucose; SCHEMBL1697421. Molecular formula: C6H12O4S. Mole weight: 180.22.
5-Thio-L-galactose (α/β-Mixture)
Novel conversion of aldopyranosides into 5-thioaldopyranosides via acyclic monothioacetals with inversion and retention of configuration at C-5. The strategy for L enantiomers was used in the synthesis of thio-L-galactose with inhibitory effect of 5-thio-L-galactose toward α-L-fucosidase. Alternative Names: 5-Thio-L-galactopyranose. CAS No. 2089578-29-8. Molecular formula: C6H12O5S. Mole weight: 196.22.
5-Thio-N-acetylglucosamine
5-Thio-N-acetylglucosamine.
5'-Tosyl-2'-deoxy Cytidine
Used to synthesize vitamin B12 coenzyme analogs containing 2'-deoxynucleoside. Uses: A nucleoside used to synthesize vitamin b12 coenzyme analogs containing 2'-deoxynucleoside. Alternative Names: 5'-(4-Methylbenzenesulfonate) 2'-Deoxycytidine; 5'-p-Toluenesulfonate 2'-Deoxycytidine. CAS No. 27999-55-9. Molecular formula: C16H19N3O6S. Mole weight: 381.4.
A derivative of 5'-Tosyl-2'-deoxy Cytidine, which is a nucleoside used to synthesize vitamin B12 coenzyme analogs containing 2'-deoxynucleoside. Alternative Names: 5'-(4-Methylbenzenesulfonate)-3'-tert-butyldimethylsilyl-2'-deoxycytidine. Molecular formula: C22H33N3O6SiS. Mole weight: 495.66.
As a derivative of 5'-Tosyl-2'-deoxy Cytidine, 5'-Tosyl-2'-deoxy-3'-tert-butyldimethylsilyl-N-[(dimethylamino)methylene]-Cytidine is a nucleoside used to synthesize vitamin B12 coenzyme analogs containing 2'-deoxynucleoside. Alternative Names: 5'-(4-Methylbenzenesulfonate)-3'-tert-butyldimethylsilyl-N-[(dimethylamino)methylene]-2'-deoxycytidine. Molecular formula: C25H38N4O6SiS. Mole weight: 550.74.
5'-Tosyl Adenosine
5'-Tosyl Adenosine is a chemically modified adenosine nucleotide in which the 5'-hydroxyl group of adenosine is substituted with a tosyl (p-toluenesulfonyl) group. This modification makes it a useful intermediate in organic synthesis and nucleoside chemistry. The tosyl group acts as a leaving group, facilitating various chemical reactions, such as nucleophilic substitutions, that can introduce other functional groups at the 5' position of adenosine. 5'-Tosyl Adenosine is often utilized in the preparation of modified nucleotides for research in biochemistry and molecular biology. Alternative Names: Adenosine 5'-(4-Methylbenzenesulfonate); 5'-O-Toluenesulfonyladenosine; 5'-Tosyladenosine. Grades: ≥95%. CAS No. 5135-30-8. Molecular formula: C17H19N5O6S. Mole weight: 421.43.
5'-Tosyl Thymidine
A nucleoside analogue as inhibitors of thymidylate kinases. Alternative Names: 5'-(4-Methylbenzenesulfonate)thymidine; 5'-O-(p-Toluenesulfonyl)thymidine; 5'-O-Tosylthymidine; NSC 69443. Grades: 98%. CAS No. 7253-19-2. Molecular formula: C17H20N2O7S. Mole weight: 396.41.
5-Tridecyl-5-deoxy-D-ribofuranose 2-O-Methanesulfonate is a vital compound used in the biomedical industry. It plays a crucial role in the treatment of certain diseases and conditions. This product is commonly utilized in the synthesis of drugs targeted towards specific cellular pathways involved in metabolic disorders and genetic diseases. Alternative Names: 2,3,4-Furantriol, tetrahydro-5-tetradecyl-, 3-methanesulfonate, (2R,3R,4R,5R)-; 2-O-Methanesulfonyl-5-C-tridecyl-5-deoxy-β-D-ribofuranose; 5-Tridecyl-5-deoxy-D-ribofuranose 2-O-Methanesulfonate. CAS No. 570414-13-0. Molecular formula: C19H38O6S. Mole weight: 394.57.
5'-Trifluoroacetamido-5'-deoxythymidine
5'-Trifluoroacetamido-5'-deoxythymidine is an exceedingly efficacious antiviral entity, demonstrating immense potential for the research of DNA virus-mediated detrimental infections, primarily those affiliated with herpesviruses. The discerning mode of action revolves around the selective suppression of viral DNA replication through specific antagonism of viral thymidine kinase, a critical and indispensible enzyme driving viral DNA enhancement. Alternative Names: 2,2,2-Trifluoro-N-(((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl)acetamide; 5'-Deoxy-5'-(2,2,2-trifluoroacetamido)thymidine. Grades: 95%. CAS No. 55812-00-5. Molecular formula: C12H14F3N3O5. Mole weight: 337.26.
5-(Trifluoromethanesulfonate) β-D-Galactofuranose 1,2,3,6-Tetrakis(2,2-dimethylpropanoate) can be used as an intermediate in the synthesis of α-Glycosidase inhibitor N-(2-Hydroxyethyl)-1-deoxy-L-altronojirimycin. Alternative Names: β-D-Galactofuranose, 1,2,3,6-tetrakis(2,2-dimethylpropanoate) 5-(trifluoromethanesulfonate). CAS No. 226877-03-8. Molecular formula: C27H43F3O12S. Mole weight: 648.68.
5-(Trifluoromethyl)cytidine
5-(Trifluoromethyl)cytidine, a remarkable antiviral compound, demonstrates exceptional potency in research of RNA virus-induced infections. This compound can be used in flaviviruses and picornaviruses, including notorious hepatitis C and poliovirus. Its mechanism of action involves the inhibition of viral replication and cellular protein research and development. Alternative Names: 5-trifluoromethylcytidine; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-(trifluoromethyl)pyrimidin-2-one. Grades: ≥95%. CAS No. 76514-02-8. Molecular formula: C10H12F3N3O5. Mole weight: 311.21.
5-Trifluoromethyl-dUTP
5-Trifluoromethyl-dUTP, a modified nucleotide that has been specifically designed for the purpose of DNA labeling and detection, has become a popular choice for PCR-based assays aimed at identifying genetic variations and mutations within DNA sequences. With its incredible precision and versatility, it has become a critical tool for researchers investigating genetic diseases and identifying potential targets for therapeutic interventions. Alternative Names: 5-Trifluoromethyl-2'-deoxyuridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N2O14P3F3 (free acid). Mole weight: 536.14 (free acid).
5-Trifluoromethyl-isocytidine
5-Trifluoromethyl-isocytidine is a highly efficacious antiviral compound utilized extensively in the research of viral afflictions encompassing respiratory syncytial virus (RSV), influenza and Zika virus. This exceptional nucleoside analog effectively hampers viral RNA research and development through its integration into viral genetic material, thereby precipitating the cessation of viral replication. Grades: ≥95%. Molecular formula: C10H12F3N3O5. Mole weight: 311.22.
5-(Trifluoromethyl)uridine
5-(Trifluoromethyl)uridine is a crucial compound primarily utilized as a precursor in the research and development of antiviral drugs, contributing to the development of novel therapies against various viral infections. This compound holds promising potential in studying diseases caused by RNA viruses. Alternative Names: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione; 5-trifluoromethyluridine. Grades: ≥95%. CAS No. 21618-67-7. Molecular formula: C10H11F3N2O6. Mole weight: 312.20.