BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Bifendate Impurity G | Bifendate Impurity G is an impurity of Bifendate used in the therapy of liver diseases. Bifendate is a medication known for its hepatoprotective effects, specifically targeting and helping alleviate symptoms related to liver inflammation and damage caused by conditions such as hepatitis. Synonyms: CHEMBL2087835; 79279-08-6; (7,7'-Dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)dimethanol; (4R)-(7,7'-Dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)dimethanol; (4S)-(7,7'-Dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)dimethanol; 1395351-58-2. Grade: > 95%. CAS No. 79279-08-6. Molecular formula: C18H18O8. Mole weight: 362.34. |  |
| Bifenthrin | Bifenthrin is a broad-spectrum synthetic pyrethroid insecticide that prolongs opening of sodium channels resulting in membrane depolarization and conductance blockade. Uses: Third generation synthetic pyrethroid. insecticide, acaricide. Synonyms: Cyclopropanecarboxylic acid, 3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethyl-, (2-methyl[1,1'-biphenyl]-3-yl)methyl ester, (1R,3R)-rel-; Cyclopropanecarboxylic acid, 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-, (2-methyl[1,1'-biphenyl]-3-yl)methyl ester, [1α,3α(Z)]-(±)-; Cyclopropanecarboxylic acid, 3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]-2,2-dimethyl-, (2-methyl[1,1'-biphenyl]-3-yl)methyl ester, (1R,3R)-rel-; (±)-Bifenthrin; Akate Master; Bifenture; Biflex; Biphenate; Biphenthrin; Biphentrin; Discipline; Empower; Fanfare; rac-Bifenthrin; Seizer; Semafor; Talstar; TalstarOne; UP Star Gold insecticide. Grade: 98%. CAS No. 82657-04-3. Molecular formula: C23H22ClF3O2. Mole weight: 422.87. | |
| Bifeprunox | Bifeprunox is a potent dopamine D2-like and 5-HT1A receptor partial agonist with pKis of 7.19 and 8.83 for cortex 5-HT1A and striatum D2, and a pEC50 of 6.37 for hippocampus 5-HT1A, respectively. It is an antipsychotic for the research of schizophrenia. Synonyms: 7-(4-(Biphenyl-3-ylmethyl)piperazin-1-yl)benzoxazol-2(3H)-one; 2(3H)-Benzoxazolone, 7-(4-((1,1'-biphenyl)-3-ylmethyl)-1-piperazinyl)-; 7-[4-([1,1'-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone. Grade: 95%. CAS No. 350992-10-8. Molecular formula: C24H23N3O2. Mole weight: 385.46. | |
| Bifeprunox mesylate | Bifeprunox mesylate is a dopamine D2 and 5-HT1A partial agonist developed as an atypical antipsychotic for the treatment of schizophrenia and other psychotic indications. Uses: Atypical antipsychotic. Synonyms: 7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one mesylate. Grade: 98%. CAS No. 350992-13-1. Molecular formula: C24H23N3O2.CH4O3S. Mole weight: 481.56. | |
| Bifonazole | Bifonazole is an imidazole antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form. Synonyms: Bay H 4502; Bay H-4502; Bay-H-4502; BayH4502. Grade: >98%. CAS No. 60628-96-8. Molecular formula: C22H18N2. Mole weight: 310.39. | |
| Bifonazole Impurity A | Bifonazole Impurity A is a top-tier impurity of Bifonazole medicinal substances. Bifonazole is esteemed for its indispensability in the therapy against an array of cutaneous mycoses. Synonyms: alpha-phenyl[1,1'-biphenyl]-4-methanol; (1,1'-Biphenyl-4-yl)phenylmethanol; Phenyl(biphenyl-4-yl)methanol; (RS)-(Biphenyl-4-yl)phenylmethanol. Grade: > 95%. CAS No. 7598-80-3. Molecular formula: C19H16O. Mole weight: 260.34. | |
| Bifonazole Impurity B | Bifonazole Impurity B stands as an imperative impurity of Bifonazole, an antifungal medications. Synonyms: 1H-Imidazole, 4-([1,1'-biphenyl]-4-ylphenylmethyl)-; 5-[phenyl-(4-phenylphenyl)methyl]-1H-imidazole; 4-([1,1'-Biphenyl]-4-yl(phenyl)methyl)-1H-imidazole; DTXSID80586251; AKOS005266655; F81813; 5-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole; 5-[([1,1'-Biphenyl]-4-yl)(phenyl)methyl]-1H-imidazole; 5-([1,1'-BIPHENYL]-4-YL(PHENYL)METHYL)-1H-IMIDAZOLE. Grade: > 95%. CAS No. 91679-37-7. Molecular formula: C22H18N2. Mole weight: 310.40. | |
| Bifonazole Impurity D | Bifonazole Impurity D showcases its presence as an impurity prominently within Bifonazole. With remarkable antifungal properties, Bifonazole effectively tackles a diverse range of fungal infections, encompassing both the intricacies of dermatomycoses and the complexities of vulvovaginal candidiasis. Synonyms: 1,3-Bis[(biphenyl-4-yl)phenylmethyl]-1H-imidazolium Chloride. Grade: > 95%. CAS No. 66600-13-3. Molecular formula: C41H33N2Cl. Mole weight: 589.18. | |
| BigLEN (mouse) | BigLEN (mouse) is a proSAAS-derived neuropeptide that acts as a GPR171 agonist. It regulates food intake in mice, and suppresses the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins. CAS No. 501036-69-7. Molecular formula: C78H130N24O22. Mole weight: 1756.03. | |
| BigLEN (mouse) acetate | BigLEN (mouse) acetate is a proSAAS-derived neuropeptide that acts as a GPR171 agonist. It regulates food intake in mice, and suppresses the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins. Molecular formula: C80H134N24O24. Mole weight: 1816.07. | |
| BigLEN (rat) | BigLEN (rat) is a proSAAS-derived peptide that acts as a potent GPR171 agonist (EC50 = 1.6 nM). It regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells. CAS No. 369377-66-2. Molecular formula: C76H128N24O23. Mole weight: 1746. | |
| BIIE 0246 | BIIE 0246 is a potent, selective and non-peptide antagonist which binds to the neuropeptide Y Y2 receptor (IC50 = 15 nM) with > 650-fold selectivity over Y1, Y4 and Y5 receptors. Synonyms: (2S)-5-(diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamide; BIIE-0246; BIIE 0246; BIIE-0246; CHEMBL540989; GTPL1547; CTK8E9439; BIIE0246. Grade: >98 %. CAS No. 246146-55-4. Molecular formula: C49H57N11O6. Mole weight: 896.05. | |
| BIIE 0246 hydrochloride | BIIE 0246 hydrochloride is a potent, selective, and competitive nonpeptide antagonist for the neuropeptide Y Y2 receptor with an IC50 of 15 nM. Synonyms: (2S)-5-((diaminomethylene)amino)-N-(2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl)-2-(2-(1-(2-oxo-2-(4-(6-oxo-6,11-dihydro-5H-dibenzo[b,e]azepin-11-yl)piperazin-1-yl)ethyl)cyclopentyl)acetamido)pentanamide dihydrochloride; N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide dihydrochloride; Cyclopentaneacetamide, N-[(1S)-4-[(aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-, hydrochloride (1:2). Grade: ≥95%. CAS No. 246146-31-6. Molecular formula: C49H57N11O6.2HCl. Mole weight: 968.98. | |
| BIIL-260 hydrochloride | BIIL-260 hydrochloride is a potent, long-acting and orally active antagonist of leukotriene B(4) receptor LTB4, with anti-inflammatory activity. It interacts with LTB4 receptors in a saturable, reversible and competitive manner, and has a high affinity for LTB4 receptors on isolated human neutrophil cell membranes with a Ki of 1.7 nM. Synonyms: 4-(3-{4-[1-(4-Hydroxy-phenyl)-1-methyl-ethyl]-phenoxymethyl}-benzyloxy)-benzamidine hydrochloride; 4-{[3-({4-[2-(4-Hydroxyphenyl)-2-propanyl]phenoxy}methyl)benzyl]oxy}benzenecarboximidamide hydrochloride (1:1); Benzenecarboximidamide, 4-[[3-[[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]methyl]phenyl]methoxy]-, hydrochloride (1:1). Grade: ≥95%. CAS No. 192581-24-1. Molecular formula: C30H31ClN2O3. Mole weight: 503.03. | |
| Bikinin | Bikinin is an ATP-competitive Arabidopsis GSK3 inhibitor, and acts as a strong activator of brassinosteroid (BR) signaling. Synonyms: 4-((5-Bromopyridin-2-yl)amino)-4-oxobutanoic acid; N-(5-Bromo-pyridin-2-yl)-succinamic acid. Grade: >98%. CAS No. 188011-69-0. Molecular formula: C9H9BrN2O3. Mole weight: 273.08. | |
| Bilaid A | Bilaid A is a tetrapeptide agonist of the μ-opioid receptor originally isolated from Penicillium. It inhibits forskolin-induced cAMP accumulation in HEK293 cells expressing the human μ-opioid receptor by 21% when used at a concentration of 10 μM. Synonyms: L-Phenylalanyl-D-valyl-L-valyl-D-phenylalanine. Grade: ≥95%. CAS No. 2393865-97-7. Molecular formula: C28H38N4O5. Mole weight: 510.62. | |
| Bilaid A1 | Bilaid A1 is a tetrapeptide agonist of the μ-opioid receptor and a derivative of bilaid A. It inhibits forskolin-induced cAMP accumulation by 47% in HEK293 cells expressing the human μ-opioid receptor when used at a concentration of 10 μM. Synonyms: L-phenylalanyl-D-valyl-L-valyl-D-phenylalaninamide; H-FVVF-NH2; H-L-Phe-D-Val-L-Val-D-Phe-NH2. Grade: ≥95%. CAS No. 2393866-02-7. Molecular formula: C28H39N5O4. Mole weight: 509.64. | |
| Bilaid B | Bilaid B is a tetrapeptide originally isolated from Penicillium. Synonyms: L-Phenylalanyl-D-valyl-L-valyl-D-tyrosine; H-FVVY-OH; H-L-Phe-D-Val-L-Val-D-Tyr-OH. Grade: ≥95%. CAS No. 2393866-06-1. Molecular formula: C28H38N4O6. Mole weight: 526.62. | |
| Bilaid B1 | Bilaid B1 is a tetrapeptide and derivative of bilaid B which is originally isolated from Penicillium. Synonyms: L-phenylalanyl-D-valyl-L-valyl-D-tyrosinamide; H-FVVY-NH2; H-L-Phe-D-Val-L-Val-D-Tyr-NH2. Grade: >95% by HPLC. CAS No. 2393866-07-2. Molecular formula: C28H39N5O5. Mole weight: 525.64. | |
| Bilaid C | Bilaid C is a tetrapeptide μ-opioid receptor agonist originally isolated from Penicillium. It inhibits forskolin-induced cAMP accumulation by 77% in HEK293 cells expressing the human μ-opioid receptor when used at a concentration of 10 μM. Bilaid C also induces inward rectifying potassium channel (Kir) currents in rat locus coeruleus slices that endogenously express high levels of the μ-opioid receptor (EC50 = 4.2 μM). Synonyms: L-Tyrosyl-D-valyl-L-valyl-D-phenylalanine; H-L-Tyr-D-Val-L-Val-D-Phe; H-YVVF. Grade: >95% by HPLC. CAS No. 2393866-13-0. Molecular formula: C28H38N4O6. Mole weight: 526.62. | |
| Bilaid C1 | Bilaid C1 is a tetrapeptide and derivative of bilaid C. It binds to the μ-opioid receptor (Ki = 3.1 μM in HEK293 cell membranes expressing the human receptor). Synonyms: L-tyrosyl-D-valyl-L-valyl-D-phenylalaninamide; H-L-Tyr-D-Val-L-Val-D-Phe-NH2; H-YVVF-NH2. Grade: >95% by HPLC. CAS No. 2393866-15-2. Molecular formula: C28H39N5O5. Mole weight: 525.64. | |
| Bilastine | Bilastine is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria. Synonyms: 2-[4-[2-[4-[1-(2-ethoxyethyl)benzimidazol-2-yl]piperidin-1-yl]ethyl]phenyl]-2-methylpropanoic acid; Bilaxten. Grade: 99%. CAS No. 202189-78-4. Molecular formula: C28H37N3O3. Mole weight: 463.622. | |
| Bilastine Impurity 1 | Bilastine Impurity 1 is an impurity of Bilastine, an antihistamine medication used for treating various allergic conditions. Synonyms: tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate. Grade: > 95%. CAS No. 953071-73-3. Molecular formula: C17H23N3O2. Mole weight: 301.39. | |
| Bilastine Impurity 2 | Bilastine Impurity 2 is an impurity of Bilastine. Synonyms: N-Boc 1-(2-Ethyoxyethyl)-2-(4-piperidinyl)-1H-benzimidazole; tert-Butyl 4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate. Grade: > 95%. CAS No. 1181267-36-6. Molecular formula: C21H31N3O3. Mole weight: 373.50. | |
| BIM 187 | BIM 187 is a bombesin/GRP receptor agonist that reduces food intake following i.p. administration. Synonyms: BIM 187; BIM187; BIM-187. CAS No. 137734-88-4. Molecular formula: C53H76N14O10. Mole weight: 1069.27. | |
| BIM 23042 Acetate | BIM 23042 Acetate is a selective antagonist of neuromedin B. Molecular formula: C65H77N11O11S2. Mole weight: 1252.50. | |
| BIM-46050 | BIM-46050 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM46050; BIM 46050; (S)-2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoic acid. Grade: >98%. CAS No. 201487-52-7. Molecular formula: C14H12N6O. Mole weight: 480.75. | |
| BIM-46068 | BIM-46068 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM 46068; BIM46068; (S)-methyl 2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoate. Grade: >98%. CAS No. 201487-53-8. Molecular formula: C17H28ClNO2. Mole weight: 494.77. | |
| BIM-46187 tetrahydrochloride | BIM-46187 tetrahydrochloride is a heterotrimeric G-protein complex inhibitor. Synonyms: 1-Propanone, 3,3'-dithiobis[2-amino-1-[(8S)-8-(cyclohexylmethyl)-5,6-dihydro-2-phenylimidazo[1,2-a]pyrazin-7(8H)-yl]-, hydrochloride (1:4), (2R,2'R)-; (2R,2'R)-3,3'-disulfanediylbis(2-amino-1-((S)-8-(cyclohexylmethyl)-2-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)propan-1-one) tetrahydrochloride; PH-064 4HCl; BIM-46187 4HCl; BIM46187 tetrahydrochloride; BIM 46187 tetrahydrochloride. Grade: ≥95%. CAS No. 2489449-03-6. Molecular formula: C44H58N8O2S2.4HCl. Mole weight: 940.96. | |
| BIM5078 | Hepatocyte nuclear factor (HNF)4α is a key regulator of gene expression in cell types playing an important role in metabolic homeostasis, such as hepatocytes, enterocytes, as well as pancreatic β cells. BIM5078 is a potent hepatocyte nuclear factor 4a (HNF4a) antagonist that directly binds to ligand-binding pocket of HNF4α with an EC50 value of 11.9 nM and modulates the expression of known HNF4a target genes. The EC50 of BIM5078 was calculated to be 11.9 nM and further analyses of the data using the Hill equation showed that the Hill coefficient for BIM5078 was 0.9, consistent with a single binding complex between BIM5078 and HNF4α. Grade: ≥98%. CAS No. 337506-43-1. Molecular formula: C14H10ClN3O4S. Mole weight: 351.8. | |
| Bimatoprost | Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Uses: For research used only. Synonyms: AGN 192024; AGN192024; AGN-192024; Bimatoprost; Lumigan; Latisse; Bimatoprostum; Lumigan. Grade: >98%. CAS No. 155206-00-1. Molecular formula: C25H37NO4. Mole weight: 415.57. | |
| Bimatoprost 13,14-Epoxide | Bimatoprost 13,14-Epoxide is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: 17-Phenyl-18,19,20-trinor-PGF2α 13,14-Epoxide; Bimatoprost Impurity 2 (Mixture of Diastereomers). Molecular formula: C25H37NO5. Mole weight: 431.56. | |
| Bimatoprost Acid | Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid; 17-Phenyl-18,19,20-trinor-PGF2α; PhXA 70; (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-heptenoic Aci. Grade: > 95%. CAS No. 38344-08-0. Molecular formula: C23H32O5. Mole weight: 388.51. | |
| Bimatoprost Acid Methyl Ester | Bimatoprost Acid Methyl Ester is an impurity of the antiglaucoma agent Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 17-Phenyl-18,19,20-trinor-PGF2α Methyl Ester. Grade: > 95%. CAS No. 38315-47-8. Molecular formula: C24H34O5. Mole weight: 402.54. | |
| Bimatoprost Impurity 10 | Bimatoprost Impurity 10 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C25H43NO6. Mole weight: 453.61. | |
| Bimatoprost Impurity 11 | Bimatoprost Impurity 11 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C25H41NO6. Mole weight: 451.59. | |
| Bimatoprost Impurity 13 | Bimatoprost Impurity 13 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C35H51NO6. Mole weight: 581.78. | |
| Bimatoprost Impurity 14 | Bimatoprost Impurity 14 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C35H53NO6. Mole weight: 583.80. | |
| Bimatoprost Impurity 3 | Bimatoprost Impurity 3 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C23H33NO4. Mole weight: 387.51. | |
| Bimatoprost Impurity 9 | Bimatoprost Impurity 9 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C34H63NO6Si. Mole weight: 609.95. | |
| Bimoclomol | Bimoclomol is a heat shock protein (HSP) coinducer that exhibits cytoprotective effects. It can be used in the treatment of cardiovascular diseases. Synonyms: (3Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)pyridine-3-carboximidoyl chloride; bimoclomol; bimoclomol, maleate (1:1). CAS No. 130493-03-7. Molecular formula: C14H20ClN3O2. Mole weight: 297.78. | |
| Bimolane | Bimolane is a topoisomerase II inhibitor. It has been widely used as an anti-neoplastic agent and for the treatment of psoriasis in China. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. Uses: Psoriasis. Synonyms: Bimolane; 4,4'-Ethylenebis[1-(morpholinomethyl)-2,6-piperazinedione]; AT-1727; AT1727; AT 1727; CCRIS 7574; CCRIS7574; CCRIS-7574; NSC 351358. Grade: 98%. CAS No. 74550-97-3. Molecular formula: C20H32N6O6. Mole weight: 452.51. | |
| Bimosiamose disodium | Bimosiamose disodium. Grade: 95%. CAS No. 187269-60-9. Molecular formula: C46H52Na2O16. Mole weight: 906.8808. | |
| BIMU 8 | BIMU 8 is a potent and selective 5-HT4 receptor full agonist (KD = 77 nM and EC50 = 18 nM for wild type 5-HT4 receptors). Synonyms: BIMU 8; BIMU8; BIMU-8; 2,3-Dihydro-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1H-benzimidazole-1-carboxamide hydrochloride; N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide hydrochloride. Grade: ≥98% by HPLC. CAS No. 134296-40-5. Molecular formula: C19H26N4O2.HCl. Mole weight: 378.9. | |
| BINA | BINA is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2) with no effect on glutamate-induced activation of other mGlu receptor subtypes. BINA exhibits antipsychotic and anxiolytic properties in mice. Synonyms: 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylic acid; Biphenylindanone A; Biphenyl-indanone A. Grade: ≥98% by HPLC. CAS No. 866823-73-6. Molecular formula: C30H30O4. Mole weight: 454.56. | |
| Bindarit | Bindarit treatment inhibits the release of MCP-1 from IL-1 stimulated osteoblast cell line Saos-2. Synonyms: Bindarit; AF-2838; AF2838; AF 2838. Grade: >98%. CAS No. 130641-38-2. Molecular formula: C19H20N2O3. Mole weight: 324.37. | |
| Binfloxacin | Binfloxacin, a bio-active chemical compound, has antibiotic effect. Uses: Binfloxacin has antibiotic effect. Synonyms: 3-Quinolinecarboxylicacid, 7-(1,4-diazabicyclo[3.2.2]non-4-yl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-; 7-(1,4-Diazabicyclo[3.2.2]non-4-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; CP73049; CP-73049. Grade: 95%. CAS No. 108437-28-1. Molecular formula: C19H22FN3O3. Mole weight: 359.39. | |
| Binimetinib | Binimetinib is an oral, highly selective MEK inhibitor. Synonyms: MEK162; MEK-162; MEK 162; ARRY162; ARRY-162; ARRY 162; ARRY438162, Binimetinib; 5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide. Grade: >98%. CAS No. 606143-89-9. Molecular formula: C17H15BrF2N4O3. Mole weight: 441.233. | |
| Binodenoson | Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor agonist. It is used to diagnose coronary artery disease. Uses: Purinergic p1 receptor agonists. Synonyms: MRE0470; MRE-0470; WRC-0470; SHA-174; 2-((Cyclohexylmethylene)hydrazino)adenosine; 2-(Cyclohexylmethylidene hydrazino) adenosine; 2-[2-(Cyclohexylmethylene)hydrazinyl]adenosine; 2-(Cyclohexylmethylidenehydrazino)adenosine; SHA 211; WRC 0470. Grade: 95%. CAS No. 144348-08-3. Molecular formula: C17H25N7O4. Mole weight: 391.42. | |
| Binucleine 2 | Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. It is also an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. Synonyms: Binucleine 2; 220088-42-6; N'-[2-(3-chloro-4-fluorophenyl)-4-cyanopyrazol-3-yl]-N,N-dimethylmethanimidamide; N'-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide; HMS546I06; Probes1_000319; Probes2_000073; CHEMBL1598812; DTXSID90430554; Binucleine 2, >=97% (HPLC); CCG-41865; MFCD00177827; AKOS040755467; NCGC00165742-01; J-014418; SR-01000631912-1; N'-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethylformimidamide. Grade: ≥98%. CAS No. 220088-42-6. Molecular formula: C13H11ClFN5. Mole weight: 291.7. | |
| BIO | BIO is a potent and reversible inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β. BIO enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells. It also promotes differentiation of cardiomyocytes from human ES and iPS cells. Synonyms: GSK-3 Inhibitor IX; 6-bromoindirubin-3-oxime; 6-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol. Grade: >98%. CAS No. 667463-62-9. Molecular formula: C16H10BrN3O2. Mole weight: 356.17. | |
| BIO 5192 | BIO 5192 is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM) with selectivity for α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053,> 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). BIO 5192 causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Synonyms: BIO-5192; AMD-15057; BIO 5192; AMD 15057; BIO5192; AMD15057; (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid. Grade: ≥98% by HPLC. CAS No. 327613-57-0. Molecular formula: C38H46Cl2N6O8S. Mole weight: 817.78. | |
| BIO5192 hydrate | BIO5192 hydrate is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd <10 pM) with selectivity for α4β1 over a range of other integrins (IC50s of 1.8, 138, 1053,>500 and >10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). It causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Synonyms: (2S)-2-({1-[(3,5-Dichlorophenyl)sulfonyl]-L-prolyl}amino)-4-({N-methyl-N-[(4-{[(2-methylphenyl)carbamoyl]amino}phenyl)acetyl]-L-leucyl}amino)butanoic acid hemihydrate; Butanoic acid, 2-[[[(2S)-1-[(3,5-dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]-, (2S)-, hydrate (2:1). Grade: ≥98%. Molecular formula: C38H46Cl2N6O8S.(1/2H2O). Mole weight: 826.79. | |
| BIO-acetoxime | BIO-acetoxime is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. It shows >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B. It has anticonvulsant and anti-infection activity. Synonyms: BIA; GSK-3 Inhibitor X; (2'Z,3'E)-6-Bromoindirubin-3'-acetoxime; (3Z)-3-[(3E)-3-(Acetoxyimino)-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 3-[(3E)-3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-, (3Z)-; 6-Bromoindirubin acetoxime; 6-Bromoindirubin-3'-acetoxime. Grade: 98%. CAS No. 667463-85-6. Molecular formula: C18H12BrN3O3. Mole weight: 398.21. | |
| Bioallethrin | Bioallethrin, classified as a pyrethroid insecticide, demonstrates efficacy in the management of various insect species, notably mosquitoes, flies, and cockroaches. Furthermore, its application extends to combatting head lice infestations. Synonyms: Esbiothrin; Depallethrin; trans-Allethrin. Grade: 95%. CAS No. 260359-57-7. Molecular formula: C19H26O3. Mole weight: 302.41. | |
| Biochanin A b-D-glucuronide | Biochanin A b-D-glucuronide is an esteemed compound, acting as a glucuronide conjugate of Biochanin A, an innate isoflavone sourced from botanical entities. Embracing an antioxidative nature, Biochanin A b-D-glucuronide reigns supreme for its anti-mutagenic as well as estrogenic attributes. Synonyms: Biochanin a 7-glucuronide; Biochanin A-7-O-beta-D-glucuronide; Biochanin A beta-D-glucuronide; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid. CAS No. 38482-76-7. Molecular formula: C22H20O11. Mole weight: 460.39. | |
| BioE-1115 | BioE-1115 is a potent and selective dual inhibitor of PAS kinase (PASK) and casein kinase 2α (CK2α) with IC50 of 4 nM and 10 μM, respectively. CAS No. 1268863-35-9. Molecular formula: C19H18FN3O2. Mole weight: 339.36. | |
| bio-THZ1 | bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a potent and selective covalent CDK7 inhibitor with an IC50 of 3.2 nM. Synonyms: (2E)-N-{4-[(3-{[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino}phenyl)carbamoyl]phenyl}-5-methyl-10,24-dioxo-28-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-14,17,20-trioxa-5,9,11,23-tetraazaoctacos-2-en-1-amide; 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[(2E)-1-[[4-[[[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]amino]-5-methyl-1,10-dioxo-14,17,20-trioxa-5,9,11-triazadocos-2-en-22-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-. Grade: ≥98%. CAS No. 1604811-14-4. Molecular formula: C52H65ClN12O8S. Mole weight: 1053.67. | |
| Bioymifi | Bioymifi is a potent and selective death receptor 5 (DR5) activator. Bioymifi works by mimicking the ability of TRAIL to stimulate clustering of DR5, triggering apoptosis. Bioymifi caused apoptosis and cell death in a variety of human cancer cell lines. Synonyms: DR5 Activator. Grade: >98%. CAS No. 1420071-30-2. Molecular formula: C22H12BrN3O4S. Mole weight: 494.32. | |
| Biperiden | Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. It is used for the adjunctive treatment of all forms of Parkinson's disease. Biperiden has an atropine-like blocking effect on all peripheral structures which are parasympathetic-innervate. Uses: Antiparkinson agents. Synonyms: Akineton; Biperiden; KL 373; KL-373; KL373. Grade: >98%. CAS No. 514-65-8. Molecular formula: C21H29NO. Mole weight: 311.46. | |
| Biperiden Hydrochloride | Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson's Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. Synonyms: Akineton hydrochloride; NSC 170950; NSC 84989; NSC170950; NSC84989; NSC-170950; NSC-84989. Grade: >98%. CAS No. 1235-82-1. Molecular formula: C21H30ClNO. Mole weight: 347.92. | |
| Biphenyl-4-sulfonyl chloride | Biphenyl-4-sulfonyl chloride is a HDAC inhibitor with synthetic applications in palladium-catalyzed desulfitative C-arylation. Synonyms: 4-phenylbenzenesulfonyl chloride. Grade: ≥ 95 %. CAS No. 1623-93-4. Molecular formula: C12H9ClO2S. Mole weight: 252.72. | |
| Bipolamine G | An antibacterial polyketide alkaloid. CAS No. 1357824-71-5. Molecular formula: C21H28N2O4. Mole weight: 372.46. | |
| Biprofen | Biprofen is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic properties. It is commonly used to relieve mild to moderate pain (e.g., headaches, dental pain, or musculoskeletal discomfort), reduce inflammation (such as in arthritis or soft tissue injuries), and lower fever. Like other NSAIDs, Biprofen works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin production. Synonyms: Flurbiprofen Impurity A; (2RS)-2-([1,1'-Biphenyl]-4-yl)propanoic acid; α-Methyl-4-biphenylacetic acid; 2-(Biphenyl-4-yl)propanoic acid; p-Phenylhydroatropic acid; (2RS)-2-(Biphenyl-4-yl)propanoic acid; 2-(4-Phenylphenyl)propionic acid; 2-(p-Biphenyl)propionic acid; α-Methylbiphenyl-4-acetic acid; Flurbiprofen EP Impurity A; α-Methyl[1,1'-biphenyl]-4-acetic acid; (±)-2-(4-Biphenyl)propionic acid; 2-((1,1'-Biphenyl]-4-yl)propanoic acid; 2-(4-Biphenyl)propionic acid; 2-(4-Biphenylyl)propanoic acid; 2-(4-Biphenylyl)propionic acid; NSC 16300; USP Flurbiprofen Related Compound A; Flurbiprofen USP Related Compound A; Flurbiprofen Related Compound A. Grade: >95%. CAS No. 6341-72-6. Molecular formula: C15H14O2. Mole weight: 226.28. | |
| Biricodar | Biricodar, also known as VX-710 or INCEL, is a novel compound that binds directly to P-gp. VX-710 concentrations of 0.5 to 2.5 M are sufficient to fully restore sensitivity of P-gp expressing cells to the cytotoxic action of paclitaxel and other cytotoxic drugs associated with the MDR phenotype. Synonyms: 1,7-dipyridin-3-ylheptan-4-yl (2S)-1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate; biricodar; Incel; N-(2-oxo-2-(3,4,5-trimethoxyphenyl)acety)piperidine-2-carboxylic acid 1,7-bis(3-pyridyl)-4-heptyl ester; VX-710; VX 710; VX710; Biricodar; Incel. CAS No. 159997-94-1. Molecular formula: C34H41N3O7. Mole weight: 603.71. | |
| Biricodar Dicitrate | Biricodar Dicitrate is the dicitrate salt form of Biricodar. Biricodar, also known as VX-710 or INCEL, is a novel compound that binds directly to P-gp. VX-710 concentrations of 0.5 to 2.5 M are sufficient to fully restore sensitivity of P-gp expressing cells to the cytotoxic action of paclitaxel and other cytotoxic drugs associated with the MDR phenotype. Synonyms: VX 710-3; (S)-1,7-di(pyridin-3-yl)heptan-4-yl 1-(2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxylate dicitrate. CAS No. 174254-13-8. Molecular formula: C46H57N3O21. Mole weight: 987.96. | |
| Birinapant | Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity. As a SMAC mimetic and IAP antagonist, TL32711 binds to and inhibits the activity of IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2. Since IAPs shield cancer cells from the apoptosis process, this agent may restore and promote the induction of apoptosis through apoptotic signaling pathways in cancer cells. IAPs are overexpressed by many cancer cell types and suppress apoptosis by binding and inhibiting active caspases-3, -7 and -9 via their baculoviral lAP repeat (BIR) domains. Check for active clinical trials or closed clinical trials using this agent. Synonyms: TL-32711; TL32711; TL 32711. Birinapant. Grade: >99.50%. CAS No. 1260251-31-7. Molecular formula: C42H56F2N8O6. Mole weight: 806.957. | |
| BIRT 377 | BIRT 377 is a negative allosteric modulator of LFA-1 (lymphocyte function-associated antigen-1) (Kd = 26 nM), which is involved in some important immunological events. BIRT 377 reversibly inhibits LFA-1 mediated binding of SKW3 leukemia cells to ICAM-1, and inhibits superantigen (SEB)-induced IL-2 production from lymphocytes in vitro and attenuates the SEB-induced increase in IL-2 plasma levels in a mouse model in vivo. Synonyms: BIRT-377; BIRT 377; BIRT377; (5R)-5-[(4-Bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione; (R)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione. Grade: ≥98% by HPLC. CAS No. 213211-10-0. Molecular formula: C18H15BrCl2N2O2. Mole weight: 442.13. | |
| Bis-2',3''-[N-(HABA-CBz)] Bis-6,4'-N-CBz Kanamycin A | Bis-2',3''-[N-(HABA-CBz) Bis-6,4'-N-CBz Kanamycin A is an Amikacin impurity A. Molecular formula: C58H74N6O23. Mole weight: 1223.23. | |
| bis(2-cyanoethyl)4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate | bis(2-cyanoethyl)4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate is an impurity of clevidipine, a dihydropyridine calcium channel blocker used as an oral antihypertensive drug. Synonyms: Bis(2-cyanoethyl)4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate. CAS No. 175688-79-6. Molecular formula: C21H19Cl2N3O4. Mole weight: 448.30. | |
Our database is helping our users find suppliers everyday.
