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A1F N-Glycan
A1F N-Glycan, the versatile biomolecule employed by the biomedical industry, is the key player in the in-depth scrutiny and diagnosis of diverse disorders - think cancer, Alzheimer's, and rheumatoid arthritis. Its multifaceted involvement in cell signaling pathways has made it a go-to diagnostic marker in countless clinical settings. Furthermore, the therapeutic potential of A1F N-Glycan has not gone unexploited; it forms the crux of several drug formulations aimed at combating these afflictions. Alternative Names: Monosialo (2,6), fucosylated biantennary (A1F); A1F glycan; FA2G2S1 Glycan; Mono-sialylated, galactosylated, core-fucosylated, bi-antennary N-linked glycan; Mannotriose-(fucosyl-di-[N-acetylglucosamine]), mono-sialyl-bis(galactosyl-N-acetylglucosaminyl); NeuNAc(Gal-GlcNAc)2Man3(GlcNAc)2Fuc; β-D-Glucopyranose, O-(N-acetyl-α-neuraminosyl)-[2→3(or 2→6)]-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-O-α-D-mannopyranosyl-[1→3(or 1→6)]-O-[O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-α-D-mannopyranosyl-[1→6(or 1→3)]]-O-β-D-mannopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-[6-deoxy-α-L-galactopyranosyl-(1→6)]-2-(acetylamino)-2-deoxy-. Grades: ≥90%. CAS No. 571188-30-2. Molecular formula: C79H131N5O58. Mol
A1 Glycan, 2-AA labelled
A1 Glycan, 2-AA labelled, an indispensable instrument for exploring the intricacies of glycans linked to multifarious illnesses, encompassing cancer, Alzheimer's, and autoimmune disorders, is an asset to biomedical research. An integral part of comprehending the biological underpinnings and workings of these ailments, this product is vital in developing efficacious therapies.
A1 Glycan, 2-AB labelled
A1 Glycan, 2-AB labelled.
A-(1-METHYLPROPYL)BENZENEACETONITRILE
A-(1-METHYLPROPYL)BENZENEACETONITRILE. CAS No. 5558-32-7.
A1 N-Glycan
A1 N-Glycan is a versatile and Indispensable compound orchestrating numerous vital biological phenomena encompassing the domains of cell adhesion, immune response modulation and the enigmatic journey of disease progression. Alternative Names: Monosialo (2,6), biantennary (A1); A1 glycan; A2G2S1 N-Glycan; NeuNAc(Gal-GlcNAc)2Man3(GlcNAc)2; Mono-sialylated, galactosylated, bi-antennary N-linked glycan. Grades: ≥90%. CAS No. 145211-79-6. Molecular formula: C73H121N5O54. Mole weight: 1932.74.
A-205804 is a potent, selective and orally bioavailable lead inhibitor of E-selectin and ICAM-1 expression, with IC50s of 20 and 25 nM for E-selectin and ICAM-1, respectively. It can be used in the study of chronic inflammatory diseases. Alternative Names: 4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide; 4-[(4-methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide; 4-(p-Tolylsulfanyl)thieno[2,3-c]pyridine-2-carboxamide. Grades: >98%. CAS No. 251992-66-2. Molecular formula: C15H12N2OS2. Mole weight: 300.40.
A20FMDV2
A20FMDV2. CAS No. 932699-03-1.
A21459 A
A21459 A is a cyclic peptide antibiotic produced by Actinoplanes sp. It has anti-clostridium (MIC 0.03-8 μg/mL) and mycoplasma (MIC 2 μg/mL) activity. Alternative Names: A21459A. Molecular formula: C41H46N10O8S. Mole weight: 838.93.
A21459 B
A21459 B is a cyclic peptide antibiotic produced by Actinoplanes sp. It has anti-clostridium (MIC 0.03-8 μg/mL) and mycoplasma (MIC 2 μg/mL) activity. Alternative Names: A21459B. Molecular formula: C40H44N10O8S. Mole weight: 824.90.
A23187 Ca-Mg
A23187 Ca-Mg, the calcium-magnesium salt of A23187, has been found to be a Ca2+ ionophore and shows pro-inflammatory and allergic activities. Uses: Used in cell activation experiments when calcium dose-response data are not required. Alternative Names: Calcimycin calcium magnesium salt; Antibiotic A23187 calcium magnesium salt; Ionophore A23187 calcium magnesium salt. Grades: ≥99%. Molecular formula: (C29H36N3O6)2Mg.(C29H36N3O6)2Ca. Mole weight: 2154.87.
A 245 (accelerator)
A 245 (accelerator). CAS No. 192334-50-2.
A-25822 A
A-25822 A is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. Alternative Names: A-25822A. CAS No. 50686-99-2. Molecular formula: C30H49NO. Mole weight: 439.71.
A-25822 B
A-25822 B is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. Alternative Names: 15-Azasterol; 15-Aza-24-methylene-8,14-cholestadiene-3beta-ol; Homoazasterol. CAS No. 50686-98-1. Molecular formula: C28H45NO. Mole weight: 411.66.
A-25822 L
A-25822 L is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. CAS No. 50687-02-1. Molecular formula: C28H43NO2. Mole weight: 425.64.
A-25822 M
A-25822 M is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. CAS No. 50886-40-3. Molecular formula: C30H47NO2. Mole weight: 453.70.
A-25822 N
A-25822 N is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. Alternative Names: Antibiotic A-25822N. CAS No. 50687-00-8. Molecular formula: C28H43NO. Mole weight: 409.65.
A-26771 B
A-26771 B is an antibiotic produced by Penicillum turbatum. Activity against gram-positive bacteria. Alternative Names: A 26771B. Grades: >98%. CAS No. 56448-20-5. Molecular formula: C20H30O7. Mole weight: 382.45.
A-26771 C
A-26771 C is an antibiotic produced by Penicillum turbatum. It has anti-gram-positive bacteria and several viral activities. Alternative Names: A26771C. CAS No. 52748-85-3. Molecular formula: C14H16N2O3S4. Mole weight: 388.55.
A-26771 E
A-26771 E is an antibiotic produced by Penicillum turbatum. Activity against gram-positive bacteria. Alternative Names: FR 106969; 2,5-Piperazinedione, 3,6-bis(methylthio)-1,4-dimethyl-3-(hydroxymethyl)-6-(phenylmethyl)-. CAS No. 50655-20-4. Molecular formula: C16H22N2O3S2. Mole weight: 354.49.
A2764 dihydrochloride
A2764 dihydrochloride is a highly selective inhibitor of TRESK (TWIK-related spinal cord K+ channel, K2P18.1). A2764 inhibits TRESK in native cells, leading to cell depolarization and increased excitability. Alternative Names: A2764 2HCl. CAS No. 861038-72-4. Molecular formula: C15H21Cl3N2O. Mole weight: 351.7.
A2793
A2793 is a dual inhibitor of TWIK-related spinal cord potassium channel (TRESK/K2P18/KCNK18) and TASK-1 (KCNK3) with IC50 of 6.8 μM for mouse TRESK. Alternative Names: Ethyl [(5-Chloroquinolin-8-yl)oxy]acetate. CAS No. 88349-90-0. Molecular formula: C13H12ClNO3. Mole weight: 265.69.
A 28695 B
A28695 is a polyether antibiotic produced by Streptomyces albus NRRL 3883. It has anti-bacterial, anti-fungal, anti-virus and insecticidal activities, and can prevent coccidia infections in poultry and rabbits. Alternative Names: Antibiotic A-28695 B. Grades: >98%. CAS No. 42617-35-6. Molecular formula: C48H82O17. Mole weight: 931.15.
A 286982
A 286982 is a potent inhibitor of the LFA-1 / ICAM-1 interaction (IC50 = 44 and 35 nM in LFA-1 / ICAM-1 binding and LFA-1-mediated cell adhesion assays, respectively). Alternative Names: A-286982; A 286982; A286982; (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one. Grades: ≥99% by HPLC. CAS No. 280749-17-9. Molecular formula: C24H27N3O4S. Mole weight: 453.55.
A2AR-agonist-1
A2AR-agonist-1 is a potent A2AR (Ki = 4.39) and ENT1(Ki = 3.47 ) agonist. Uses: A potent a2ar and ent1 agonist. Alternative Names: N-(2-(1H-indol-3-yl)ethyl)-Adenosine. Grades: ≥98%. CAS No. 41552-95-8. Molecular formula: C20H22N6O4. Mole weight: 410.43.
A2AR antagonist 1
A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively. Alternative Names: 1-[(2-fluorophenyl)methyl]-4-(furan-2-yl)pyrazolo[3,4-d]pyrimidin-6-amine. Grades: ≥95%. CAS No. 443103-97-7. Molecular formula: C16H12FN5O. Mole weight: 309.30.
A2B N-Glycan
A2B N-Glycan is a fundamental constituent employed in dissecting intricate glycosylation arrangements. It assumes a pivotal function in developing the formulation of therapeutics directed towards a myriad of ailments such as neoplasms, neurodegenerative maladies like Alzheimer's and immune system dysfunctions. Alternative Names: Sialo, bisected, biantennary N-linked glycan.
A2B receptor antagonist 1
A potent antagonist of A2B adenosine receptor. Alternative Names: 1H-Purine-2,6-dione, 3,9-dihydro-8-[1-(phenylmethyl)-1H-pyrazol-4-yl]-1,3-dipropyl-. CAS No. 531506-36-2. Molecular formula: C21H24N6O2. Mole weight: 392.45.
A2B receptor antagonist 2
A2B receptor antagonist 2 is a member of quinazolines. It is also an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively. Alternative Names: N-(4,6,7-trimethylquinazolin-2-yl)guanidine; 1-(4,6,7-trimethylquinazolin-2-yl)guanidine. Grades: 95%. CAS No. 784-90-7. Molecular formula: C12H15N5. Mole weight: 229.28.
a-[2-(Dimethylamino)ethyl]hydrocinnamic acid ethyl ester-[d6] is the labelled analogue of a-[2-(Dimethylamino)ethyl]hydrocinnamic acid ethyl ester, which is an antihistamine agent. Alternative Names: a-[2-(Dimethylamino)ethyl]hydrocinnamic acid ethyl ester-d6; α-[2-(Dimethylamino-d6)ethyl] Hydrocinnamic Acid Ethyl Ester; α-[2-(Dimethylamino-d6)ethyl]benzenepropanoic Acid Ethyl Ester; Benzenepropanoic acid, α-[2-(dimethyl-d6-amino)ethyl]-, ethyl ester. Grades: ≥98%. CAS No. 1346601-78-2. Molecular formula: C15H17D6NO2. Mole weight: 255.39.
a-(2-Ethoxyethynyl)-cyclopentanemethanol
a-(2-Ethoxyethynyl)-cyclopentanemethanol. CAS No. 1038404-02-2. Molecular formula: C10H16O2. Mole weight: 168.23.
A 2E Trifluoroacetic Acid Salt
A 2E Trifluoroacetic Acid Salt. Molecular formula: C42H58NO·C2HF3O2. Mole weight: 592.93.
A2FB N-Glycan
A2FB N-Glycan is an indispensable compound in the biomedical field, playing a significant role in elucidating and deciphering the intricate N-glycosylation profiles discernible in diverse pharmaceuticals and ailments. Alternative Names: sialyl, fucosylated, bisected biantennary N-linked glycan.
A2F Glycan, 2-AA labelled
A2F Glycan, 2-AA labelled, a highly specialized chemical utilized in the biomedical industry, possesses immense potential in decoding the intricate processes of glycosylation in the human body, playing a pivotal role in shedding light on several degenerative diseases, including Alzheimer's and Parkinson's. Its effectiveness lies in serving as an indispensable tool in drug development, with its ability to aid in targeting these illnesses. This scientific marvel has indeed revolutionized the study of glycosylation through its unparalleled contributions to medical research and development.
A2F Glycan, 2-AB labelled
A2F Glycan, 2-AB labelled.
A2F N-Glycan
A2F N-Glycan is a biomolecule widely found in human cells, involved in glycosylation process. It is commonly used in the biomedicine industry for studying age-related macular degeneration (AMD) as well as other diseases related to glycation, such as Alzheimer's and diabetes. A2F N-Glycan also plays a crucial role in developing therapeutic drugs targeted to these diseases. Alternative Names: Disialo, galactosylated, fucosylated, biantennary (A2F); Di-sialylated, galactosylated, core-fucosylated bi-antennary N-linked glycan; FA2G2S2 Glycan; Mannotriose-(fucosyl-di-[N-acetylglucosamine]), bis(sialyl-galactosyl-N-acetylglucosaminyl); (NeuNAc-Gal-GlcNAc)2Man2(Fuc)(GlcNAc)2; A2F glycan; O-(N-Acetyl-α-neuraminosyl)-[2→3(or 2→6)]-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-O-α-D-mannopyranosyl-(1→3)-O-[O-(N-acetyl-α-neuraminosyl)-[2→3(or 2→6)]-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-α-D-mannopyranosyl-(1→6)]-O-β-D-mannopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-[6-deoxy-α-L-galactopyranosyl-(1→6)]-2-(acetylamino)-2-deoxy-D-glucose. Grades: ≥90%. CAS No. 108341-22-6. Molecular formula: C90H148N6O66. Mole weight: 2370.14.
A2G1 Glycan, 2-AA labelled
A2G1 Glycan, 2-AA labelled is a crucial component in the biomedicine industry used to study glycosylation patterns, which plays a critical role in numerous diseases, including cancer, diabetes, and inflammation. As a fluorescently labelled glycan, it enables researchers to investigate the glycosylation process related to protein-protein and protein-ligand interactions, leading to better understanding and potential therapeutic interventions for these diseases.
A2G1 Glycan, 2-AB labelled
A2G1 Glycan, 2-AB labelled.
A2G1 N-Glycan
A2G1 N-Glycan is a vital component used for studying glycosylation and its impact on diseases such as cancer, autoimmune disorders and neurodegenerative diseases. This glycan plays a crucial role in understanding cellular processes, protein interactions and targeted compound delivery. It aids in the characterization and analysis of glycoproteins. Alternative Names: Asialo-, bi-antennary N-linked glycan.
A2 Glycan, 2-AA labelled
A2 Glycan, 2-AA labelled is a vital tool in biomedicine used for studying glycan structures and their involvement in various diseases. It is utilized to analyze glycan compositions and monitor alterations in glycosylation patterns. Alternative Names: A2 N-linked oligosaccharide; A2G2S2; G2S2.
A2 Glycan, 2-AB labelled
A2 Glycan, 2-AB labelled.
A2-Iso5-2DC18
A2-Iso5-2DC18 is a top-performing lipid for mRNA delivery in bone marrow-derived dendritic cells (BMDCs), BMDMs and HeLa cells. Alternative Names: ethyl 5,5-di((z)-heptadec-8-en-1-yl)-1-(3-(pyrrolidin-1-yl)propyl)-2,5-dihydro-1h-imidazole-2-carboxylate. Molecular formula: C47H87N3O2. Mole weight: 726.21.
a2-Macroglobulin (human proteinmoiety reduced) (9CI). Alternative Names: A2M; A-2-M, HUMAN; ALPHA2M; ALPHA2-MACROGLOBIN, HUMAN; ALPHA2-MACROGLOBULIN; ALPHA2-MACROGLOBULIN, HUMAN; ALPHA2-MACROGLOBULIN, HUMAN PLASMA; ALPHA-2 MACROGLOBULIN PLASMA. Grades: 95%. CAS No. 95568-41-5.
A2-MHC
A peptide used in the research on the treatment of melanoma.
A2 N-Glycan
A2 N-Glycan is an indispensable biocompatible and bioactive glycobiology compound, aiding in the meticulous analysand comprehensive characterization of glycoproteins. Alternative Names: Disialo (2,6), biantennary (A2); A2 glycan; A2G2S2 N-glycan; Di-sialylated, galactosylated, bi-antennary N-linked glycan Mannotriose-di-(N-acetyl-D-glucosamine), bis([N-acetyl-D-neuraminyl]-galactosyl-[N-acetyl-D-glucosaminyl]). Grades: 95%. CAS No. 71496-55-4. Molecular formula: C84H138N6O62. Mole weight: 2224.00.
A2-PE
A2-PE. Uses: A pigment that forms as a byproduct of the visual cycle in vertebrates, which accumulates in retinal pigment epithelial cells over time leading to decline in cellular function. Alternative Names: 2-[(1E,3E,5E,7E)-2,6-Dimethyl-8-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3,5,7-octatetraen-1-yl]-1-[4-hydroxy-4-oxido-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-4-[(1E,3E,5E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3,5-hexatrien-1-yl]pyridinium; DP-A2-PE. CAS No. 863180-05-6. Molecular formula: C77H125NO8P. Mole weight: 1223.79.
A2ti-1
A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. Alternative Names: Acetamide, 2-[[4-(2-ethylphenyl)-5-[(2-methylphenoxy)methyl]-4H-1,2,4-triazol-3-yl]thio]-; 2-({4-(2-Ethylphenyl)-5-[(2-methylphenoxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide. Grades: ≥98%. CAS No. 570390-00-0. Molecular formula: C20H22N4O2S. Mole weight: 382.48.
A2ti-2
A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with an IC50 of 230 μM. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It protects against human papillomavirus type 16 (HPV16) infection. Alternative Names: 2-{5-[(2-methylphenoxy)methyl]-4-phenyl-1,2,4-triazol-3-ylthio}acetamide; Acetamide, 2-[[5-[(2-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl]thio]-; 2-({5-[(2-Methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide. Grades: ≥98%. CAS No. 482646-13-9. Molecular formula: C18H18N4O2S. Mole weight: 354.43.
A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Alternative Names: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. Grades: ≥95%. CAS No. 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57.
A-317491 sodium salt hydrate
A-317491 sodium salt hydrate is a potent, selective antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. It reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux. Grades: 99%. Molecular formula: C33H29NNaO9. Mole weight: 606.57.
A-317567
Acid Sensing Ion Channels (ASICs) are a group of sodium-selective ion channels that are activated by low extracellular pH. A-317567 is a novel non-amiloride blocker. Alternative Names: A317567; 6-{2-[2-methyl-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]cyclopropyl}naphthalene-2-carboximidamide. CAS No. 371217-32-2. Molecular formula: C27H31N3. Mole weight: 397.56.
A 32390A
A 32390A is an antibiotic produced by Pyrenochaeta sp. (NRRL-5786). It has anti-gram-positive bacteria and fungi activity. It also inhibits the activity of dopamine tetra-hydroxylase, can reduce the level of norepinephrine in the heart and adrenal glands, and has a hypotensive effect on hypertensive rats. Alternative Names: 1,6-Di-O-2-isocyano-3-methylcrotonyl-D-mannitol; Antibiotic A 32390A; A32390A. Grades: >98%. CAS No. 61241-59-6. Molecular formula: C18H24N2O8. Mole weight: 396.39.
A-32724 A
A-32724 A is an antibiotic produced by Chaetomella raphigera A-32724. It has anti-Gram-positive bacteria, negative bacteria and fungi activity, and has the effect of lowering blood pressure and inhibiting Glucosyl tranferaese (Glucosyl tranferaese). CAS No. 85528-23-0. Molecular formula: C33H56Na2O11S2. Mole weight: 738.90.
A-32724 B
A-32724 B is an antibiotic produced by Chaetomella raphigera A-32724. It has anti-Gram-positive bacteria, negative bacteria and fungi activity, and has the effect of lowering blood pressure and inhibiting Glucosyl tranferaese (Glucosyl tranferaese). CAS No. 85537-32-2. Molecular formula: C33H56Na2O11S2. Mole weight: 738.90.
A 33
A 33 is a potent and selective PDE4B inhibitor (IC50 = 15 nM) that exhibits >100-fold selectivity for PDE4B over 4D. Alternative Names: 2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid. Grades: ≥98%. CAS No. 915082-52-9. Molecular formula: C19H18ClN3O2S. Mole weight: 387.88.
A 331440 dihydrochloride
A 331440 dihydrochloride is a histamine H3 receptor antagonist (Ki = 21.7 and 22.7 nM for rat and human H3 receptors, respectively). A 331440 reduces weight in a diet-induced obesity model. Alternative Names: A-331440 dihydrochloride; A 331440 dihydrochloride; A331440 dihydrochloride; 4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1049740-32-0. Molecular formula: C22H27N3O.2HCl. Mole weight: 422.39.
A-33853 is an antibiotic produced by Streptomyces sp. (NRRL 12068). It has anti-gram-positive bacteria, viruses, poultry coccidioides, trichomonas and mosquito larvae. Alternative Names: Antibiotic A 33853; 4-Benzoxazolecarboxylic acid, 2-(3-hydroxy-2-(((3-hydroxy-2-pyridinyl)carbonyl)amino)phenyl)-. Grades: >98%. CAS No. 80148-45-4. Molecular formula: C20H13N3O6. Mole weight: 391.33.
A 350619
A 350619 is an activator of soluble guanylyl cyclase (sGC) that stimulates basal sGC and synergistically activates sGC in the presence of NO. It is effective for the use of ED treatment. Alternative Names: A-350619; A350619; 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide. CAS No. 538368-27-3. Molecular formula: C21H25ClN2OS. Mole weight: 389.0.
A 350619 hydrochloride
A 350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC) that stimulates basal sGC and synergistically activates sGC in the presence of NO. It is effective for the use of ED treatment. Uses: The treatment of ed. Alternative Names: A-350619 hydrochloride; A350619 hydrochloride; A 350619 hydrochloride; 3-[2-[(4-Chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1217201-17-6. Molecular formula: C21H25ClN2OS.HCl. Mole weight: 425.41.
A 357300 hydrochloride
A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derived neuroblastoma s.c. xenograft growth rate with a treatment-to-control (T/C) ratio at day 24 of 0.19 (P < 0.001) without toxicity. Uses: Novel treatment of neuroblastoma. Alternative Names: A-357300; A 357300; A357300; N'-(3-amino-2-hydroxy-5-(isopropylthio)pentanoyl)-3-chlorobenzohydrazide hydrochloride. Grades: 99%. CAS No. 369358-07-6. Molecular formula: C15H22ClN3O3S.HCl. Mole weight: 396.33.
A-366
A-366 is a peptide-competitive inhibitor of the G9a/GLP histone lysine methyltransferase (IC50 = 3.3 nM) and is approximately 1000-fold selective over other methyltransferases. Alternative Names: A 366; A366. CAS No. 1527503-11-2. Molecular formula: C19H27N3O2. Mole weight: 329.44.
A-366833
A-366833 is a an agonist at neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Uses: Neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Alternative Names: A-366833; A 366833; A366833; 5-[(1R,5S)-3,6-diazabicyclo[3.2.0]heptan-6-yl]pyridine-3-carbonitrile. Grades: ≥98%. CAS No. 370882-41-0. Molecular formula: C11H12N4. Mole weight: 200.24.
A37
A37 is an aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC50 = 4.6 μM; Ki = 300 nM). It competitively binds to the aldehyde binding pocket of ALDH1A1, resulting in the disruption of spheroid formation and a decrease of cell viability in ovarian cancer cells in vitro. Alternative Names: Ethyl 2-[[3,4-dihydro-4-oxo-3-[3-(1-pyrrolidinyl)propyl][1]benzothieno[3,2-d]pyrimidin-2-yl]thio]acetate; CM037; CM-037; CM 037; A37; A-37; A 37. Grades: ≥97% by HPLC. CAS No. 896795-60-1. Molecular formula: C21H25N3O3S2. Mole weight: 431.57.
A-381393
A-381393 is a potent and selective dopamine D4 receptor agonist. Alternative Names: A 381393; CHEMBL127257. Grades: 98%. CAS No. 726174-00-1. Molecular formula: 20H24N4. Mole weight: 320.4.
A 39183A
It is an anthraquinone antibiotic produced by the strain of streptomyces sp. It has broad spectrum antimicrobial activity against both sensitive and resistant strains, including many anaerobic bacteria. It also has the activity against gram-positive and gram-negative bacteria. Alternative Names: Antibiotic A 39183A; (1S,1'S,2S,2'S)-1,1'-Diacetyl-2,2',5,5',10,10'-hexahydroxy-2,2'-dimethyl-2,2',3,3'-tetrahydro-9,9'-bianthracene-4,4'(1H,1'H)-dione. Grades: >95% by HPLC. CAS No. 79426-51-0. Molecular formula: C34H30O10. Mole weight: 598.60.
A-395
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions, and can effectively inhibit the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM. Alternative Names: 3-Pyrrolidinamine, 1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-[4-[4-(methylsulfonyl)-1-piperazinyl]phenyl]-, (3R,4S)-; (3R,4S)-1-(7-Fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-{4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-3-pyrrolidinamine. Grades: ≥95%. CAS No. 2089148-72-9. Molecular formula: C26H35FN4O2S. Mole weight: 486.65.