BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
A3-APO is an antimicrobial peptide produced by Synthetic construct. It has antibacterial activity. Alternative Names: (H-Chex-Arg-Pro-Asp-Lys-Pro-Arg-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Arg-Pro-Val-Arg)2-Dab-NH2 (where Chex is 1-amino-cyclohexane carboxylic acid and Dab is 2,4-diamino-butyric acid). Grades: 97%.
A3 Glycan, 2-AA labelled
A3 Glycan, 2-AA labelled, a critical and indispensable instrument in the biomedical sector, is utilized for exploring glycan expression in diverse illnesses, notably cancer and autoimmune disorders. It acts as the ideal substance for glycan analysis and characterization by advanced technologies like mass spectrometry and chromatography. Furthermore, A3 Glycan, 2-AA labelled is crucial for triggering glycomics-related biomarker discovery scientific investigations ensuing precision medication breakthroughs.
A3N19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with an EC50 of 3.28 nM against HIV-1 IIIB. Alternative Names: A3N19|CHEMBL4752774|HY-146031|CS-0497849. Grades: ≥98% (HPLC). CAS No. 2249755-49-3. Molecular formula: C31H31N9O2S. Mole weight: 593.7.
A3 N-Glycan
A3 N-Glycan is a vital biomolecule commonly found on the surface of many cells. It plays a crucial role in various biological processes, such as cell signaling, immune response, and disease progression. This particular N-glycan is extensively studied in the biomedical industry due to its involvement in numerous diseases, including cancer, autoimmune disorders, and infectious diseases. Alternative Names: Trisialylated, galactosylated, triantennary (A3); A3 glycan; A3G3S3 Glycan; (NeuNAc-Gal-GlcNAc)3Man3(GlcNAc)2; Tri-sialylated, galactosylated, tri-antennary N-linked glycan; Mannotriose-di-(N-acetyl-D-glucosamine), tris(sialyl-galactosyl-N-acetyl-D-glucosaminyl; D-Glucose, O-(N-acetyl-α-neuraminosyl)-[2→3(or 2→6)]-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→2)-O-[O. Grades: ≥85%. CAS No. 145164-24-5. Molecular formula: C109H178N8O80. Mole weight: 2880.59.
A3(or5)-[[4-[ethyl[2-(trimethylammonio)ethyl]amino]phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium dimethyl disulfate. CAS No. 97861-86-4. Molecular formula: C17H29N7.2CH3O4S.
A40926
A40926 is an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. It acts by inhibiting the synthesis of bacterial cell wall. It is also the precursor to dalbavanain. Alternative Names: Dalbavancin Impurity. Grades: 75%. CAS No. 102961-72-8. Molecular formula: C88H101Cl3N10O28. Mole weight: 1853.15.
A40926-B2
A40926-B2 is an impurity of A40926, an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. A40926 acts by inhibiting the synthesis of bacterial cell wall. Alternative Names: Antibiotic A-40926 B2. CAS No. 871088-55-0. Molecular formula: C84H90Cl2N8O29. Mole weight: 1746.5.
A40926-ISO B0
A40926-ISO B0 is an impurity of A40926, an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. A40926 acts by inhibiting the synthesis of bacterial cell wall.
A40926-MAG
A40926-MAG is an impurity of A40926, an antibiotic against Gram positive bacteria particularly for Neisseria gonorrhoeae. A40926 acts by inhibiting the synthesis of bacterial cell wall.
A 410099.1
A 410099.1 is a high affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Alternative Names: N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride. Grades: ≥98%. CAS No. 762274-58-8. Molecular formula: C27H40N4O3·HCl. Mole weight: 505.09.
A 410099.1 amide-PEG2-amine-Boc
A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand containing an IAP ligand and a PEG linker of 2 O(CH2)2 units with Boc protected terminal amine, can be used to bind to the target protein ligand. CAS No. 2415256-16-3. Molecular formula: C38H60N6O8. Mole weight: 728.92.
A 410099.1 amide-PEG3-amine-Boc
A 410099.1 amide-PEG3-amine-Boc is a functionalized IAP ligand containing an IAP ligand and a PEG linker of 3 O(CH2)2 units with Boc protected terminal amine, can be used to bind to the target protein ligand. CAS No. 2415256-19-6. Molecular formula: C40H64N6O9. Mole weight: 772.97.
A 410099.1, amine-Boc hydrochloride
A 410099.1, amine-Boc hydrochloride is an IAP ligand that can be used in the synthesis of PROTAC, whose Boc protected terminal amine support to bind a target protein ligand. CAS No. 2374122-37-7. Molecular formula: C32H50ClN5O5. Mole weight: 620.22.
A41030A
A41030A is a glycopeptide antibiotic produced by Streptomyces virginiae A41030. Activity against gram-positive bacteria. Alternative Names: Desulfo-A47394. CAS No. 89139-41-3. Molecular formula: C58H44Cl3N7O18. Mole weight: 1233.36.
A41030B
A41030B is a glycopeptide antibiotic produced by Streptomyces virginiae A41030. Activity against gram-positive bacteria. Alternative Names: Antibiotic L 17392; Teicoplanin aglycone; Antibiotic A 41030B. CAS No. 89139-42-4. Molecular formula: C58H45Cl2N7O18. Mole weight: 1198.92.
A41030C
A41030C is a glycopeptide antibiotic produced by Streptomyces virginiae A41030. Activity against gram-positive bacteria. Alternative Names: Antibiotic A 41030C; 7-Demethyl-64-O-demethyl-19-deoxy-11-O-galactosyl-22,31,35-trichlororistomycin A aglycone; Ristomycin A aglycone, 7-demethyl-64-O-demethyl-19-deoxy-11-O-galactosyl-22,31,35-trichloro-. CAS No. 89140-21-6. Molecular formula: C64H54Cl3N7O23. Mole weight: 1395.50.
A41030E
A41030E is a glycopeptide antibiotic produced by Streptomyces virginiae A41030. Activity against gram-positive bacteria. Alternative Names: Antibiotic A 41030 E. CAS No. 89139-43-5. Molecular formula: C58H46ClN7O18. Mole weight: 1164.47.
A41030F
A41030F is a glycopeptide antibiotic produced by Streptomyces virginiae A41030. Activity against gram-positive bacteria. Alternative Names: Antibiotic A 41030 F. CAS No. 89140-20-5. Molecular formula: C70H64Cl3N7O28. Mole weight: 1557.64.
A-412997
A-412997. CAS No. 630118-64-8.
A 412997 dihydrochloride
A 412997 dihydrochloride is a potent and selective agonist for the dopamine D4 receptor (Ki = 7.9 and 12.1 nM for human D4 and rat D4, receptors) with no activity for other dopamine receptors. Alternative Names: A-412997 dihydrochloride; A412997 dihydrochloride; A-412997 dihydrochloride; N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide. Grades: ≥98% by HPLC. CAS No. 1347744-96-0. Molecular formula: C19H23N3O.2HCl. Mole weight: 382.33.
A 419259
A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM. Alternative Names: A419259; A-419259; RK 20449; RK20449; RK-20449. Grades: >98%. CAS No. 364042-47-7. Molecular formula: C29H34N6O. Mole weight: 482.62.
A 419259 trihydrochloride
Potent Hck inhibitor (IC50 = 0.43 nM). Also inhibits other Src family kinases (SFKs). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Also inhibits acute myeloid leukemia (AML) stem cell proliferation in vitro and in vivo. Alternative Names: A419259 trihydrochloride; A-419259 trihydrochloride; RK 20449 trihydrochloride; RK20449 trihydrochloride; RK-20449 trihydrochloride. Grades: >98%. CAS No. 1435934-25-0. Molecular formula: C29H37Cl3N6O. Mole weight: 592.0.
A 425619
A 425619 is a potent and selective TRPV1 antagonist (IC50 = 3-9 nM) that inhibits TRPV1 activation by anandamide and N-arachidonoyl-dopamine. A 425619 exhibits an inhibitory effect against inflammatory, postoperative and osteoarthritic in vivo pain models. Uses: Analgesic. Alternative Names: A-425619; A 425619; A425619; N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea. Grades: ≥98% by HPLC. CAS No. 581809-67-8. Molecular formula: C18H14F3N3O. Mole weight: 345.32.
A-42867
A-42867 is a glycopeptide antibiotic produced by Nocardia sp. It has activity against Gram-positive bacteria, mycobacteria, Enterococcus faecalis and Clostridium difficile. Alternative Names: Antibiotic 42867; 22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-44-O-de(2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)-44-O-(O-(6-deoxy-alpha-D-mannopyranosyl)-D-glucosyl)vancomycin. CAS No. 122753-17-7. Molecular formula: C72H86ClN9O28. Mole weight: 1560.95.
A 437203
A 437203 is a selective dopamine (DA) D3 receptor antagonist suited to evaluate the physiological role(s) of D3 receptors. A 437203 shows an approximately 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. Alternative Names: 2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one; 2-(3-(4-(2-tert-butyl-6-trifluoromethylpyrimidin-4-yl)piperazin-1-yl)propylsulfanyl)-3H-pyrimidin-4-one fumarate; A 437203; A-437203; A437203; 1160247-85-7; 220519-07-3 (anhydrous); 220519-06-2 (anhydrous free base). Grades: >98%. CAS No. 220519-06-2. Molecular formula: C20H27F3N6OS. Mole weight: 456.53.
A-438079 HCl
A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9. Alternative Names: A-438079 HCl; A 438079 HCl; A438079 HCl. Grades: 98%. CAS No. 899431-18-6. Molecular formula: C13H10Cl3N5. Mole weight: 342.61.
A 438079 hydrochloride
A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores. Alternative Names: 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride; A438079 hydrochloride; A 438079 hydrochloride. Grades: >98 %. CAS No. 899507-36-9. Molecular formula: C13H10Cl3N5. Mole weight: 342.61.
A-443654
A-443654 is a potent small-molecule inhibitor of all three Akt serine / threonine kinases, induces Akt Ser-473 phosphorylation in all human cancer cell lines tested, including PTEN- and TSC2-deficient lines. It inhibits Akt-dependent signal transduction in cells and in vivo in a dose-responsive manner. Alternative Names: A443564; A-443564; A 443564. Grades: >98%. CAS No. 552325-16-3. Molecular formula: C24H23N5O. Mole weight: 397.47.
A47934
A47934 is a glycopeptide antibiotic produced by Streptomyces toyocaensis NRRL15009. Activity against gram-positive bacteria. Alternative Names: A-47934 Antibiotic; Antibiotic A 47934. CAS No. 90039-80-8. Molecular formula: C58H44Cl3N7O21S. Mole weight: 1313.43.
A 484954
A 484954 is a eukaryotic elongation factor-2 (eEF-2) kinase inhibitor (IC50 = 0.28 μM in enzymatic assay). A 484954 reduces eEF-2 phosphorylation with little effect on cancer cell growth. Alternative Names: A-484954; A 484954; A484954; 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide. Grades: ≥98% by HPLC. CAS No. 142557-61-7. Molecular formula: C13H15N5O3. Mole weight: 289.29.
A-485
A-485 is an inhibitor of the histone acetyltransferase p300/CBP (IC50 = 60 nM). Alternative Names: (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide. Grades: ≥98%. CAS No. 1889279-16-6. Molecular formula: C25H24F4N4O5. Mole weight: 536.48.
a-(4-Bromophenyl)-2-pyridineacetonitrile
a-(4-Bromophenyl)-2-pyridineacetonitrile, is an intermediate in the synthesis of Bromopheniramine Maleate, a derivative of Pheniramine (P297200), used to treat allergic conditions such as hay fever or urticaria. Alternative Names: alpha-(4-Bromophenyl)pyridine-2-acetonitrile; 2-(4-bromophenyl)-2-pyridin-2-ylacetonitrile; 2-Pyridineacetonitrile,a-(4-bromophenyl)-; alpha-(4-Bromophenyl)-2-pyridineacetonitrile; 2-(4-BROMOPHENYL)-2-(PYRIDIN-2-YL)ACETONITRILE. CAS No. 85750-24-9. Molecular formula: C13H9BrN2. Mole weight: 273.13.
A-(4-BROMOPHENYL)-4-METHOXYCINNAMIC ACID
A-(4-BROMOPHENYL)-4-METHOXYCINNAMIC ACID. Alternative Names: A-(4-BROMOPHENYL)-4-METHOXYCINNAMIC ACID. Grades: 95%. CAS No. 14335-72-9. Molecular formula: C16H13BrO3. Mole weight: 333.18.
A-(4-chloro-3-nitrophenyl)acetamide
A-(4-chloro-3-nitrophenyl)acetamide. CAS No. 5540-60-3. Molecular formula: C8H7ClN2O3. Mole weight: 214.6.
A-500359A
A-500359A is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has the activity of inhibiting translocase-1, IC50 is 0.017 μmol/L, and the IC50 of inhibiting peptidoglycan biosynthesis is 0.68 μmol/L. It also has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. CAS No. 254449-20-2. Molecular formula: C24H33N5O12. Mole weight: 583.54.
A-500359C
A-500359C is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. CAS No. 254449-21-3. Molecular formula: C23H31N5O12. Mole weight: 569.52.
A-500359D
A-500359D is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. CAS No. 254449-22-4. Molecular formula: C24H33N5O11. Mole weight: 567.54.
A-500359E
A-500359E is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Alternative Names: A-500359 E. Molecular formula: C18H23N3O12. Mole weight: 473.39.
A-500359F
A-500359F is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Molecular formula: C17H21N3O12. Mole weight: 459.36.
A-500359G
A-500359G is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Molecular formula: C22H29N5O12. Mole weight: 555.49.
A-500359H
A-500359H is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Molecular formula: C16H19N3O12. Mole weight: 445.33.
A-500359 M-1
A-500359 M-1 is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Alternative Names: N-[2-({2-[(6-{[(2S,3S,4R,5R)-5-(2,4-Dioxo(1,3-dihydropyrimidinyl))-4-hydroxy-3-methoxyoxolan-2-yl]carbamoylmethoxy}(4S,5S,6S)-4,5-dihydroxy-4H-5,6-dihydropyran-2-yl)carbonylamino]ethyl}disulfanyl)ethyl]acetamide. Molecular formula: C23H33N5O12S2. Mole weight: 635.66.
A-500359 M-2
A-500359 M-2 is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Alternative Names: N-((3R,6R)-3-Methyl-5-oxo(1,4-thiazaperhydroepin-6-yl))(6-{[(2S,3S,4R,5R)-5-(2,4-dioxo(1,3-dihydropyrimidinyl))-4-hydroxy-3-methoxyoxolan-2-yl]carbamoylmethoxy}(4S,5S,6S)-4,5-dihydroxy(4H-5,6-dihydropyran-2-yl))carboxamide. Molecular formula: C23H31N5O12S. Mole weight: 601.58.
A-51493A
A-51493A is an anthraquinone antibiotic produced by Streptomyces humifer. Activity against gram-positive bacteria. Alternative Names: 121245-06-5; A51493A; AC1L52A8; A51493A; A-51493A; PL024209. Grades: >98%. CAS No. 121245-06-5. Molecular formula: C30H31NO10. Mole weight: 565.57.
A-53930 A
A-53930 A is a Ca2+ channel blocker produced by Streptomyces vinaceusdrappus SANK 62394. It selectively blocks the activity of N-type Ca2+ channels, but does not inhibit L-type Ca2+ channels. It has weak activity against Gram-negative bacteria. Alternative Names: 4H-Imidazo(4,5-c)pyridin-4-one, 1,3a,5,6,7,7a-hexahydro-2-((2-((3-amino-6-(((3S)-3-amino-6-(((3S)-3-amino-6-(((3S)-3,6-diamino-1-oxohexyl)amino)-1-oxohexyl)amino)-1-oxohexyl)amino)-1-oxohexyl)amino)-6-O-(aminocarbonyl)-2-deoxy-beta-D-gulopyranosyl)amino)-7-hydroxy-, (3aS,7R,7aS)-. CAS No. 182410-79-3. Molecular formula: C37H70N14O11. Mole weight: 887.04.
A-53930 B
A-53930 B is a Ca2+ channel blocker produced by Streptomyces vinaceusdrappus SANK 62394. It selectively blocks the activity of N-type Ca2+ channels, but does not inhibit L-type Ca2+ channels. It has weak activity against Gram-negative bacteria. Alternative Names: 4H-Imidazo(4,5-c)pyridin-4-one, 1,3a,5,6,7,7a-hexahydro-2-((6-O-(aminocarbonyl)-2-deoxy-2-(((3S,10S,17S,24S,31S)-3,10,17,24,31,34-hexamino-1,8,15,22,29-pentaoxo-7,14,21,28-tetraazatetratriacont-1-yl)amino)-beta-D-gulopyranosyl)amino)-7-hydroxy-, (3aS,7R,7aS)-. CAS No. 182697-76-3. Molecular formula: C43H82N16O12. Mole weight: 1015.21.
A-54145A
A metabolite of Argatroban, a medication for the prevention and treatment of thrombosis. Alternative Names: Antibiotic A 54145A; A-54145 A. Grades: > 95%. CAS No. 153886-68-1. Molecular formula: C10H13NO3S. Mole weight: 227.28.
A-54145A1
A-54145A1 is an ester peptide antibiotic produced by Streptomyces fradiae. It has anti-Gram-positive bacteria activity with an MIC of 0.25-32 μg/mL. Alternative Names: Antibiotic A 54145A1; A-54145 A1. CAS No. 129804-73-5. Molecular formula: C72H109N17O27. Mole weight: 1644.73.
A-54145B
A-54145B is an ester peptide antibiotic produced by Streptomyces fradiae. It has anti-Gram-positive bacteria activity with an MIC of 0.25-32 μg/mL. Alternative Names: A-54145 B. CAS No. 129804-74-6. Molecular formula: C73H111N17O27. Mole weight: 1658.76.
A-54145B1
A-54145B1 is an ester peptide antibiotic produced by Streptomyces fradiae. It has anti-Gram-positive bacteria activity with an MIC of 0.25-32 μg/mL. Alternative Names: A-54145 B1. CAS No. 129804-75-7. Molecular formula: C73H111N17O27. Mole weight: 1658.76.
A-54145C
A-54145C is an ester peptide antibiotic produced by Streptomyces fradiae. It has anti-Gram-positive bacteria activity with an MIC of 0.25-32 μg/mL. Alternative Names: A-54145 C. CAS No. 129804-76-8. Molecular formula: C73H111N17O27. Mole weight: 1658.76.
A-54145D
A-54145D is an ester peptide antibiotic produced by Streptomyces fradiae. It has anti-Gram-positive bacteria activity with an MIC of 0.25-32 μg/mL. Alternative Names: A-54145 D. CAS No. 129804-77-9. Molecular formula: C73H111N17O27. Mole weight: 1658.76.
A-54145E
A-54145E is an ester peptide antibiotic produced by Streptomyces fradiae. It has anti-Gram-positive bacteria activity with an MIC of 0.25-32 μg/mL. Alternative Names: A-54145 E. CAS No. 129804-78-0. Molecular formula: C74H113N17O27. Mole weight: 1672.78.
A-54145F
A-54145F is an ester peptide antibiotic produced by Streptomyces fradiae. It has anti-Gram-positive bacteria activity with an MIC of 0.25-32 μg/mL. Alternative Names: A-54145 F. Molecular formula: C71H107N17O27. Mole weight: 1630.70.
A 54556A
A 54556A is an unusual depsipeptide antibiotic produced by the strain of streptomyces hawaiiensis. It can inhibit the growth of 786-O, 769-P and ACHN renal carcinoma cells in MTT assay. A 54556A may be a potential chemotherapeutic agent for treatment of renal carcinoma. It has potent activity against gram-positive and gram-negative bacteria, including MRSA. Alternative Names: Antibiotic A 54556A; A 54556 factor A; ADEP 1; Acyldepsipeptide 1; Acyldepsipeptide A; N-[[(2E,4E,6E)-1-Oxo-2,4,6-octatrienyl]-L-Phe-]cyclo[L-Ser*-L-Pro-N-methyl-L-Ala-L-Ala-4beta-methyl-L-Pro-]. Grades: >95% by HPLC. CAS No. 95398-45-1. Molecular formula: C38H50N6O8. Mole weight: 718.84.
A-54556B
A-54556B is a natural acyldepsipeptide (ADEP) antibiotic isolated from the fermentation broth of S. hawaiiensis. It has activity against Gram-positive bacteria and many strains of anaerobic bacteria. Alternative Names: A-54556 Factor B; Antibiotic A-54556B; N-[(2E,4E,6E)-1-Oxo-2,4,6-octatrien-1-yl]-L-phenylalanyl-L-seryl-L-prolyl-N-methyl-L-alanyl-L-alanyl-L-proline (6→2)-lactone. Grades: ≥98%. CAS No. 1629166-56-8. Molecular formula: C37H48N6O8. Mole weight: 704.81.
A549 Transfection Reagent
BOC Sciences offers reagents specifically formulated and optimized for the transfection of A549. Uses: Lung cancer research and drug discovery and gene expression studies.
A 582941
A 582941 is a selective α7 nAChR partial agonist which is effetive for both rat and human α7 receptors (Ki = 10.8 and 16.7 nM respectively). Alternative Names: A-582941; A 582941; A582941; Octahydro-2-methyl-5-(6-phenyl-3-pyridazinyl)-pyrrolo[3,4-c]pyrrole; (3aR,6aS)-2-methyl-5-(6-phenylpyridazin-3-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole. Grades: ≥98% by HPLC. CAS No. 848591-90-2. Molecular formula: C17H20N4. Mole weight: 280.37.
A 582941 HCl
A 582941 is a selective α7 nAChR partial agonist which is effetive for both rat and human α7 receptors (Ki = 10.8 and 16.7 nM respectively). Alternative Names: A-582941 HCl; A582941 HCl. Molecular formula: C17H21ClN4. Mole weight: 316.83.
A 58365 A
A58365 A is an enzyme inhibitor produced by Streptomyces chromofuscus A58365.1. It has the effect of inhibiting angiotensin transferase (ACE). Alternative Names: 6-Indolizinepropanoic acid, 3-carboxy-1,2,3,5-tetrahydro-8-hydroxy-5-oxo-, (-)-. Grades: >98%. CAS No. 87896-52-4. Molecular formula: C12H13NO6. Mole weight: 267.23.
A 58365 B
A58365 B is an enzyme inhibitor produced by Streptomyces chromofuscus A58365.1. It has the effect of inhibiting angiotensin transferase (ACE). Alternative Names: 2H-Quinolizine-7-propanoic acid, 4-carboxy-1,3,4,6-tetrahydro-9-hydroxy-6-oxo-. Grades: >98%. CAS No. 87896-53-5. Molecular formula: C13H15NO6. Mole weight: 281.26.
A[5']P5[5']A SODIUM SALT
A[5']P5[5']A SODIUM SALT is a paramount biomedical product, standing as a distinguished tool for selective autoimmune conditions and inflammatory dysfunctions. It exhibits its might as a formidable cGAS-STING pathway stimulator. Alternative Names: Adenosine 5'-(hexahydrogen pentaphosphate), 5'.5'-ester with adenosine, pentasodium salt; P1,P5-Di(adenosine-5') pentaphosphate pentasodium salt; Diadenosine pentaphosphate pentasodium salt. Grades: ≥95%. CAS No. 4097-4-5. Molecular formula: C20H24N10Na5O22P5. Mole weight: 1026.28.
A 61603 hydrobromide
A 61603 hydrobromide is a potent and selective α-adrenoceptor agonist with 35-fold selectivity for α1A over α1B or α1D sites. Activation of the α1A-adrenergic receptor by A 61603 induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro (EC50 = 6.9 nmol/L). Alternative Names: A61603 Hydrobromide; A 61603 Hydrobromide; A-61603 Hydrobromide; N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide hydrobromide. CAS No. 107756-30-9. Molecular formula: C14H19N3O3S.HBr. Mole weight: 390.29.
Inhibition of p110α alone by A66 treatment is sufficient to block insulin signalling to Akt/PKB in certain cell lines that harbor H1047R mutations in PIK3CA and have high levels of p110α and class-Ia PI3K activity. Alternative Names: A66; A-66; A 66. Grades: >98%. CAS No. 1166227-08-2. Molecular formula: C17H23N5O2S2. Mole weight: 393.53.
A-674563
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC. Alternative Names: A674563; A 674563; Benzeneethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, (αS)-; (αS)-α-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine; (S)-1-((5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine. Grades: >98%. CAS No. 552325-73-2. Molecular formula: C22H22N4O. Mole weight: 358.44.
A-674563 dihydrochloride
A-674563, an Akt1 inhibitor with a Ki of 11 nM, is moderately potent against PKA and >30-fold selective for Akt1 over PKC. Alternative Names: A-674563 2HCl; Benzeneethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, hydrochloride (1:2), (αS)-; (αS)-α-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine dihydrochloride; (S)-1-((5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine hydrochloride; A 674563 dihydrochloride; A674563 dihydrochloride. Grades: ≥95%. CAS No. 2759293-92-8. Molecular formula: C22H22N4O.2HCl. Mole weight: 431.36.