BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
×
Product
Description
Suppliers Website
AA 29504
AA 29504 is a positive allosteric modulator of GABAA receptors with anxiolytic activity. It modulates both α4β3δ-containing extrasynaptic receptors and α1β3γ2S-containing receptors in Xenopus oocytes. AA 29504 is potentially used for the treatment of schizophrenia. Uses: Potential treatment of schizophrenia. Alternative Names: AA 29504; AA29504; AA-29504; N1-Ethoxycarbonyl-N4-[(2,4,6-trimethylpheny)lmethyl]-1,2,4-triaminobenzene; ethyl N-[2-amino-4-[(2,4,6-trimethylphenyl)methylamino]phenyl]carbamate. Grades: ≥98% by HPLC. CAS No. 945828-50-2. Molecular formula: C19H25N3O2. Mole weight: 327.42.
a,a,3,5-Tetramethyl-benzeneacetonitrile
a,a,3,5-Tetramethyl-benzeneacetonitrile (cas# 93748-07-3) is a compound useful in organic synthesis. Alternative Names: 2-(3,5-Dimethylphenyl)-2-methylpropionitrile. CAS No. 93748-07-3. Molecular formula: C12H15N. Mole weight: 173.25.
AA38-3
AA38-3 is a serine hydrolase (SH) inhibitor that can inhibit three SHs, ABHD6, ABHD11, and FAAH. Alternative Names: 4-Nitrophenyl piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-nitrophenyl ester; 4-Nitrophenyl 1-piperidinecarboxylate. Grades: ≥95%. CAS No. 65815-76-1. Molecular formula: C12H14N2O4. Mole weight: 250.25.
AA3-DLin
AA3-Dlin is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA. Alternative Names: Piperazine-bis(ethyl octadeca-9,12-dienoate); HY-148830; CS-0642689; Piperazine-1,4-diylbis(ethane-2,1-diyl) (9E,9'E,12E,12'E)-bis(octadeca-9,12-dienoate); 2832061-33-1. CAS No. 2832061-33-1. Molecular formula: C44H78N2O4. Mole weight: 699.1.
AA41612
AA41612 is a novel antagonist of melanopsin-mediated phototransduction. Alternative Names: AA 41612; AA-41612; 1-((2,5-Dichloro-4-methoxyphenyl)sulfonyl)piperidine. Grades: >98%. CAS No. 433690-62-1. Molecular formula: C12H15Cl2NO3S. Mole weight: 324.22.
AA-57
AA-57 is an acidic lipophilic antibiotic produced by Streptomyces sp. AA-57. It has anti-gram-positive bacteria, negative bacteria and mycobacterial activity. Alternative Names: AA-57; Pentaleno(1,6a-c)pyran-5-carboxylic acid, 1-(chloromethyl)-1,2,4,4a,6a,7-hexahydro-1-hydroxy-7,8-dimethyl-2-oxo-, (1S-(1alpha,4aalpha,6abeta,7alpha,9aR*))-; Pentaleno(1,3a-c)pyran-5-carboxylic acid, 1,2,4,4a,6a,7-hexadyro-1-(chloromethyl)-7,8-dimethyl-1-hydroxy-2-oxo-. Grades: >98%. CAS No. 68026-87-9. Molecular formula: C15H17ClO5. Mole weight: 312.74.
AA-861
AA-861. Alternative Names: 2-[12-HYDROXYDODECA-5,10-DIYNYL]-3,5,6-TRIMETHYL-P-BENZOQUINONE; AA-861; docebenone; 2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione; 2-(12-Hydroxydodecane-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone; Decebenone. CAS No. 80809-81-0. Molecular formula: C21H26O3. Mole weight: 326.43.
AA92593
AA92593 is a selective and competitive OPN4 (melanopsin) antagonist. It blocks melanopsin activity and stimulates α-melanocyte-stimulating hormone (α-MSH) expression and induces melanin distribution in the melanophores, which darkens the embryo. Alternative Names: 1-((4-Methoxy-3-methylphenyl)sulfonyl)piperidine. Grades: >98%. CAS No. 457961-34-1. Molecular formula: C13H19NO3S. Mole weight: 269.36.
AAA-10 formic
AAA-10 formic is an orally active gut bacterial bile salt hydrolases (BSH) inhibitor. Molecular formula: C26H43FO7S. Mole weight: 518.68.
AA-AMPSA
AA / AMPS is the copolymer of acrylic acid and 2-acrylanmido-2-methylpropanesulfonic acid (AMPS). Uses: Aa / amps can be used as scale inhibitor and dispersant in open circulating cooling water system, oilfield refill water system, metallurgy system and iron & steel plants to prevent sediment of ferric oxide. when built with organophosphorines and zinc salt, the suitable ph value is 7.0~9. 5. aa / amps can also be used as dyeing auxiliaries for textile. Alternative Names: AA-AMPS; Acrylic Acid-2-Acrylamido-2-Methylpropane Sulfonic Acid Copolymer; Sulfonated Polyacrylic Acid Copolymer. CAS No. 40623-75-4.
AABD-SH (4-Acetamido-7-mercapto-2,1,3-benzoxadiazole) [for HPLC Labeling] is usefuil for developing an ultrafine atmospheric pressure plasma jet. Alternative Names: AABD-SH; N-(4-sulfanyl-2,1,3-benzoxadiazol-7-yl)acetamide; N-(7-SULFANYL-2,1,3-BENZOXADIAZOL-4-YL)ACETAMIDE; 4-Acetamido-7-mercaptobenzofurazan. CAS No. 254973-02-9. Molecular formula: C8H7N3O2S. Mole weight: 209.22.
Aacephate-[Methoxy-d3,Thiomethoxy-d3]
Acephate-[d6] is a labelled Acephate, which is an organophosphate foliar insecticide. Alternative Names: Aacephate (methoxy-d3,thiomethoxy-d3). Grades: 98% by CP; 98% atom D. CAS No. 2109699-73-0. Molecular formula: C4H4D6NO3PS. Mole weight: 189.20.
AACOCF, an anlogue of arachidonic acid, is a slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Alternative Names: 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one; Arachidonyl trifluoromethyl ketone; Arachidonyltrifluoromethane. CAS No. 149301-79-1. Molecular formula: C21H31F3O. Mole weight: 356.47.
A(Ac)-TOM-CE Phosphoramidite
2'-O-TOM-A(Ac) Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It features a 2'-O-TOM (2'-O-tomc) modification attached to an adenosine (A) nucleotide, along with an acetyl (Ac) group. This modification enhances stability and protects against nuclease degradation. It is often employed in applications such as RNA interference, gene expression modulation, and therapeutic RNA-based treatments. The synthesis of RNA using monomers containing the 2'-O-Triisopropylsilyloxymethyl (TOM) group (TOM-Protecting-Group) has very high coupling efficiency along with fast, simple deprotection. Alternative Names: 5'-Dimethoxytrityl-N-acetyl-Adenosine, 2'-O-triisopropylsilyloxymethyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Acetyl-2'-O-[(triisopropylsilyloxy)methyl]-3'-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)adenosine; Adenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methyleth. Grades: ≥95%. CAS No. 253586-13-9. Molecular formula: C52H72N7O9PSi. Mole weight: 998.23.
a,a'-dicyano-2,5-dihydroxy-1,4-phenylenediacetate
a,a'-dicyano-2,5-dihydroxy-1,4-phenylenediacetate. Alternative Names: 57271-90-6;diethyl2,2'-(2,5-dihydroxy-1,4-phenylene)bis(cyanoacetate);diethyl2,2'-(2,5-dihydroxybenzene-1,4-diyl)bis(cyanoacetate);ethyl2-cyano-2-[4-(1-cyano-2-ethoxy-2-oxoethyl)-2,5-dihydroxyphenyl]acetate;NSC78843;AC1Q4QLZ. Grades: 95%. CAS No. 57271-90-6. Molecular formula: C16H16 N2 O6. Mole weight: 332.30804.
a,a-Difluoro-benzeneacetyl Chloride
a,a-Difluoro-benzeneacetyl Chloride. Alternative Names: 2,2-difluoro-2-phenylacetyl chloride; PhCF2COCl; 2,2-difluoro-2-phenylacetylchloride; Benzeneacetyl chloride, a,a-difluoro-. CAS No. 312-24-3. Molecular formula: C8H5OF2Cl. Mole weight: 190.57.
a,a-Difluorophenylacetic acid ethyl ester
a,a-Difluorophenylacetic acid ethyl ester. Alternative Names: ethyl difluoro(phenyl)acetate; ethyl alpha,alpha-difluorophenylacetate. CAS No. 2248-46-6. Molecular formula: C10H10F2O2. Mole weight: 200.183.
a,a-Diisopropylhomoveratronitrile
a,a-Diisopropylhomoveratronitrile. Alternative Names: a,a-Diisopropylhomoveratronitrile; ALPHA,ALPHA-DIISOPROPYLHOMOVERATRONITRILE. CAS No. 51698-54-5. Molecular formula: C16H23NO2. Mole weight: 261.35932.
a,a'-Dimethoxy-a,a,a',a'-tetraphenyl-p-xylene
a,a'-Dimethoxy-a,a,a',a'-tetraphenyl-p-xylene. Alternative Names: A,A'-DIMETHOXY-A,A,A',A'-TETRAPHENYL-P-XYLENE; ALPHA,ALPHA'-DIMETHOXY-ALPHA,ALPHA,ALPHA',ALPHA'-TETRAPHENYL-P-XYLENE. CAS No. 68883-10-3. Molecular formula: C34H30O2. Mole weight: 470.61.
a,a-Dimethyl-6-(phenylmethoxy)-1H-indole-3-acetonitrile. Alternative Names: 1H-Indole-3-acetonitrile, a,a-dimethyl-6-(phenylmethoxy)-. Grades: 95%. CAS No. 629662-39-1. Molecular formula: C19H18N2O. Mole weight: 290.364.
AADvac-1
AADvac-1 is an active vaccine designed to raise antibodies against pathological tau protein (the primary constituent of neurofibrillary pathology in AD). These antibodies are expected to prevent tau protein from aggregating, to facilitate the removal of tau protein aggregates and prevent the spreading of pathology, slowing or halting the progress of the disease. Alternative Names: AADvac-1; Alzheimer's disease vaccine - Axon Neuroscience; Axon peptide 108 conjugated to KLH; Axon peptide 108 coupled to KLH. CAS No. 2307465-24-1.
AAE871
AAE871 is a type I FLT3 inhibitor. Alternative Names: AAE-871; AAE 871; 9H-Purine-2,6-diamine, N2-(trans-4-aminocyclohexyl)-9-ethyl-N6-[4-(1-piperidinylsulfonyl)phenyl]-. Grades: >98%. CAS No. 289479-07-8. Molecular formula: C24H34N8O2S. Mole weight: 498.64.
Aaf-Arg-OH HCl
Aaf-Arg-OH HCl, a substrate of carboxypeptidase B-type enzymes, has been used to determine the activation of TAFI (thrombin activatable fibrinolysis inhibitor, carboxypeptidase U) by thrombin and thrombin-thrombomodulin. Alternative Names: N-(4-Methoxyphenylazoformyl)-Arg-OH HCl; N2-{[(4-Methoxyphenyl)diazenyl]carbonyl}-L-arginine hydrochloride (1:1); L-Arginine, N2-[[2-(4-methoxyphenyl)diazenyl]carbonyl]-, hydrochloride (1:1). Grades: ≥95% by HPLC. CAS No. 442158-31-8. Molecular formula: C14H20N6O4.HCl. Mole weight: 372.81.
AAF-CMK trifluoroacetate salt
AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Alternative Names: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. Grades: ≥95%. CAS No. 184901-82-4. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84.
AAFP
AAFP. Alternative Names: N-(4-METHOXYPHENYLAZOFORMYL)-L-PHENYLALANINE POTASSIUM SALT; 4-METHOXYPHENYLAZOFORMYL-PHE POTASSIUM SALT; AAFP. CAS No. 396717-86-5. Molecular formula: C17H16KN3O4. Mole weight: 365.43.
A,A'-HYDRAZODIISOBUTYRONITRILE
A,A'-HYDRAZODIISOBUTYRONITRILE. Alternative Names: 2,2'-HYDRAZO-BIS(2-METHYLPROPIONITRILE); A,A'-HYDRAZODIISOBUTYRONITRILE; 2,2'-(Hydrazine-1,2-diyl)bis(2-methylpropanenitrile); 2,2'-Hydrazobis(2-methylpropiononitrile); 2,2'-Hydrazobis(isobutyronitrile). CAS No. 6869-7-4. Molecular formula: C8H14N4. Mole weight: 166.22.
AAI101
AAI101 is a novel β-lactamase inhibitor with activity against extended-spectrum β-lactamases (ESBL), as well as, some class A and class D carbapenemases. Uses: Beta-lactamase inhibitors. Alternative Names: AAI-101; AAI101. CAS No. 1001404-83-6. Molecular formula: C11H14N4O5S. Mole weight: 314.32.
AAKIQASFRGHMARKK
AAKIQASFRGHMARKK. Alternative Names: RC3; PROTEIN KINASE SELECTIDE; PROTEIN KINASE C SELECTIDE(TM) SUBSTRATE; NEUROGRANIN (28-43); NEUROGRANIN FRAGMENT 28-43; NEUROGRANIN 28-43 [AAKIQASFRGHMARKK]. Grades: 95%. CAS No. 146554-17-8. Molecular formula: C78H134N28O19S. Mole weight: 1800.14.
AAL-993
AAL-993 is a VEGFR tyrosine kinase inhibitor that possesses dual inhibition of VEGFR signaling and HIF-1α expression through ERK inhibition without affecting Akt phosphorylation. Alternative Names: AAL 993; AAL993; 2-((4-pyridyl)methyl)amino-N-(3-(trifluoromethyl)phenyl)benzamide. Grades: >98%. CAS No. 269390-77-4. Molecular formula: C20H16F3N3O. Mole weight: 371.36.
AalDefD
AalDefD is an antimicrobial peptide produced by Aedes albopictus (Yellowfever mosquito). It has antimicrobial activity and has three intramolecular disulfide bonds. Alternative Names: Aedes albopictus defensin D; Defensin-D; AaeDefD; Ala-Thr-Cys-Asp-Leu-Leu-Ser-Gly-Phe-Gly-Val-Gly-Asp-Ser-Ala-Cys-Ala-Ala-His-Cys-Ile-Ala-Arg-Gly-Asn-Arg-Gly-Gly-Tyr-Cys-Asn-Ser-Lys-Lys-Val-Cys-Val-Cys-Pro-Ile. Grades: >98%. Molecular formula: C166H264N52O52S6. Mole weight: 4012.65.
AAPCONA. CAS No. 34797-69-8. Molecular formula: C10H9ClN2O4. Mole weight: 256.64.
AA-PEG-AA, MW 600-20k
AA-PEG-AA has two identical activated carboxyl terminal groups. The carboxyl group reacts with the amino group to modify the molecule. Homobifunctionalized PEG derivatives have wide applications in peptides, proteins, lipids, other small molecules and surface modifications. The PEG is a highly hydrophilic molecule containing a large amount of ethoxy groups, which causes high hydrodynamic volume in aqueous solution. Alternative Names: AA-PEG-AA; Acetic acid-PEG-Acetic acid; α,ω-Diacryloyl poly(ethylene glycol). Mole weight: Customizable.
Aaptamine
Aaptamine, a spongean alkaloid isolated from a sea sponge Aaptos aaptos, is a competitive antagonist of α-adrenoceptor and activates the p21 promoter in a p53-independent manner. Alternative Names: 8,9-dimethoxy-1H-benzo[de][1,6]naphthyridine. Grades: ≥95%. CAS No. 85547-22-4. Molecular formula: C13H12N2O2. Mole weight: 228.3.
AAQ chloride
AAQ chloride is a photoswitchable Kv channel blocker (IC50 = 2 and 64 μM at 500 nm and 380 nm, respectively) that switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. AAQ chloride also stimulates action potential firing of hippocampal neurons in vitro at 500 nm and restores visual responsiveness in blind mice at 380 nm. Alternative Names: N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminium chloride. Grades: ≥98% by HPLC. Molecular formula: C23H30ClN5O2. Mole weight: 443.97.
a-Artemether-[d3]
Labelled Derivative of Artemisinin (A777500). Shows antimalarial and antifungal activity. Alternative Names: (+)-α-Artemether-d3; SM 229-d3; α-Artemether-d3; α-Dihydroartemisinin Μethyl-d3 Εther; (3R,5aS,6R,8aS,9R,10R,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-d3. CAS No. 93861-34-8. Molecular formula: C16H23D3O5. Mole weight: 301.39.
AAT-008
AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16.3 nM in a human EP4 functional assay). Alternative Names: 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid. Grades: ≥98%. CAS No. 847727-81-5. Molecular formula: C21H16ClFN2O4. Mole weight: 414.8.
AAT II
AAT II. Alternative Names: AAT II; AAT II RESTRICTION ENZYME; Restriction endonuclease Aat II. Grades: 95%. CAS No. 84067-31-2.
AA-UTP
AA-UTP is a substrate for RNA polymerase with amino group that can be labeled with a fluorescent dye, biotin or other markers. Alternative Names: 5- (3- Aminoallyl)uridine- 5'- O- triphosphate. Grades: ≥ 95% by HPLC. CAS No. 85280-66-6. Molecular formula: C12H20N3O14P3 (free acid). Mole weight: 539.2 (free acid).
AB-001
AB-001. Alternative Names: 1-adamantyl-(1-pentylindol-3-yl)methanone; AB-001; 1345973-49-0; JWH018adamantylanalog; SCHEMBL17308094; SHWDYCMMUPPWQM-UHFFFAOYSA-N. Grades: 95%. CAS No. 1345973-49-0. Molecular formula: C24H31NO. Mole weight: 349.50904.
AB-0022A
AB-0022A is an antibiotic produced by Dictyostelium purpureum K1001. It has anti-Gram-positive bacteria activity, the MIC against Staphylococcus is 0.39-3.13 μg/mL, and the MIC against Streptococcus and Enterococcus is 25-50 μg/mL. Alternative Names: AB0022A. Molecular formula: C20H19Cl3O6. Mole weight: 461.72.
AB023 A
AB023 A is a pentaene macrolide antibiotic produced by Streptomyces sp. SD581 and K9925278. It has the activity against several pathogenic fungi such as black koji and Candida albicans. The MIC of Botrytis cinerea is 5 μg/mL. Alternative Names: Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,10,12,14,16-hexahydroxy-3,15,27,28-tetramethyl-. CAS No. 141443-39-2. Molecular formula: C31H50O8. Mole weight: 550.72.
AB023 B
AB023 B is a pentaene macrolide antibiotic produced by Streptomyces sp. SD581 and K9925278. It has the activity against several pathogenic fungi such as black koji and Candida albicans. CAS No. 141443-40-5. Molecular formula: C32H52O8. Mole weight: 564.75.
AB05831
An analogue of deoxynojirimycin, was found to be a potent inhibitor of a number of N-acetylglucosaminidases. Alternative Names: 2-Acetamido-1,2-Dideoxynojirmycin; 2-Acetamido-1,2,5-trideoxy-1,5-imino-D-glucitol; 2-Addnj; AdNJ; DNJNAc. Grades: 98%. CAS No. 105265-96-1. Molecular formula: C8H16N2O4. Mole weight: 204.22.
Ab-14E1
Ab-14E1.
AB-25E9
AB-25E9.
AB 3217-A
AB3217-A is an anti-mite substance produced by Streptomyces platensis AB2317. Alternative Names: Antibiotic AB3217A; AB-3217-A. Grades: >98%. CAS No. 139158-99-9. Molecular formula: C17H23NO7. Mole weight: 353.37.
AB-400
AB-400 is a tetraene macrolide produced by Streptomyces costae. It has anti-Candida activity with an MIC of 4.6-18.0 μg/mL, which is lower than Nystatin and Amphotrecin B. Molecular formula: C33H48N2O12. Mole weight: 664.74.
AB-423
AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells. Alternative Names: 5-[[(2R)-butan-2-yl]sulfamoyl]-N-(3,4-difluorophenyl)-2-fluorobenzamide. Grades: ≥98%. CAS No. 1572510-80-5. Molecular formula: C17H17F3N2O3S. Mole weight: 386.39.
AB-452
AB-452. Alternative Names: AB-452;SCHEMBL21327220;EX-A8160;HY-163149;CS-0928532;2226178-35-2. CAS No. 2226178-35-2. Molecular formula: C21H26N2O6. Mole weight: 402.44.
AB 5046 A
AB 5046 A is a substance produced by Nodulisporium AB5046 that causes plant chlorosis. It has the activity of inducing chlorosis of monocotyledonous and dicotyledonous plants. Alternative Names: 2-Cyclohexen-1-one, 3,5-dihydroxy-2-(1-oxobutyl)-, (+/-)-; (+/-)-3,5-Dihydroxy-2-(1-oxobutyl)-2-cyclohexen-1-one. Grades: >98%. CAS No. 154037-62-4. Molecular formula: C10H14O4. Mole weight: 198.22.
AB 5046 B
AB 5046 B is a substance produced by Nodulisporium AB5046 that causes plant chlorosis. It has the activity of inducing chlorosis of monocotyledonous and dicotyledonous plants. Alternative Names: 2-Cyclohexen-1-one, 2-acetyl-3,5-dihydroxy-, (+/-)-. Grades: >98%. CAS No. 154037-63-5. Molecular formula: C8H10O4. Mole weight: 170.16.
AB-506
AB-506. Alternative Names: AB-506;2245020-50-0;(1-methyl-1H-1,2,4-triazol-3-yl)methyl {(1S)-4-[(3-chloro-4-fluorophenyl)carbamoyl]-7-fluoro-2,3-dihydro-1H-inden-1-yl}carbamate;CHEMBL5184427;SCHEMBL21777388;DA-70443;HY-148768;CS-0639035;YWE. CAS No. 2245020-50-0. Molecular formula: C28H30Cl2N2O. Mole weight: 481.5.
AB-5529
AB-5529. Alternative Names: AB-5529. CAS No. 220383-76-6. Molecular formula: C23H30O6. Mole weight: 402.48.
AB-680 ammonium
AB-680 ammonium is a highly potent, reversible and selective CD73 (an ecto-nucleotidase) inhibitor, with a Ki of 4.9 pM for hCD73, and displays >10,000-fold selectivity over related ecto-nucleotidases CD39. It has antitumor activity. Alternative Names: 6-Chloro-N-[(1S)-1-(2-fluorophenyl)ethyl]-1-{5-O-[hydroxy(phosphonomethyl)phosphoryl]-β-D-ribofuranosyl}-1H-pyrazolo[3,4-b]pyridin-4-amine ammonium (1:2). Molecular formula: C20H30ClFN6O9P2. Mole weight: 614.89.
AB-729
AB-729 is a nucleoside analogue that acts as an RNA interference (RNAi) and can inhibit viral replication, reducing HBV antigens. AB-729 binds to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes entry into hepatocytes through asialoglycoprotein receptor (ASGR). Alternative Names: AB-729|HY-132603. Grades: ≥98% (HPLC). CAS No. 2634739-74-3.
AB-836. Alternative Names: AB-836;2445597-31-7;MHY5H5WMW6;CHEMBL5314907;SCHEMBL22094191;EX-A6898;DA-50078;HY-148348;CS-0619622;N'-(3-Cyano-4-fluorophenyl)-N-[(1R)-1-(6,7-difluoro-1,2-dihydro-1-oxo-4-isoquinolinyl)ethyl]-N-methylurea;Urea, N'-(3-cyano-4-fluorophenyl)-N-[(1R)-1-(6,7-difluoro-1,2-dihydro-1-oxo-4-isoquinolinyl)ethyl]-N-methyl-. CAS No. 2445597-31-7. Molecular formula: C21H23N3O8. Mole weight: 445.4.
AB928
AB928 is a dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively. It potently blocks the immunosuppressive effects of high adenosine concentrations in the tumor microenvironment. Alternative Names: A2Ar/A2bR antagonist-1; 3-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile. CAS No. 2239273-34-6. Molecular formula: C23H22N8O. Mole weight: 426.5.
Abacavir
Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Alternative Names: Ziagen. Grades: >98%. CAS No. 136470-78-5. Molecular formula: C14H18N6O. Mole weight: 286.33.