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Abemaciclib metabolite M2
Abemaciclib metabolite M2, a metabolite of Abemaciclib, is a potent inhibitor of CDK4 and CDK6 with IC50s of 1-3 nM. It has anticancer activity. Alternative Names: LSN2839567; 5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzimidazol-6-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-2-pyrimidinamine; 2-Pyrimidinamine, 5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-. Grades: ≥95%. CAS No. 1231930-57-6. Molecular formula: C25H28F2N8. Mole weight: 478.54.
Abemaciclib metabolite M20
Abemaciclib metabolite M20, an active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for cancer treatment. Alternative Names: LSN3106726; 2-Methanol Abemaciclib; CDK4/6-IN-4; {6-[2-({5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl}amino)-5-fluoro-4-pyrimidinyl]-4-fluoro-1-isopropyl-1H-benzimidazol-2-yl}methanol; 1H-Benzimidazole-2-methanol, 6-[2-[[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]amino]-5-fluoro-4-pyrimidinyl]-4-fluoro-1-(1-methylethyl)-. Grades: ≥98%. CAS No. 2138499-06-4. Molecular formula: C27H32F2N8O. Mole weight: 522.59.
a-(Benzoylamino)benzeneacetamide-[d10]
Intermediate in the preparation of labelled Cephalexin. Alternative Names: N-(α-Carbamoylbenzyl)benzamide-d10. CAS No. 1246814-47-0. Molecular formula: C15H4D10N2O2. Mole weight: 264.35.
A-BENZYL-N-CBZ-D-GLUCOSAMINIDE CRYSTALLI NE. Alternative Names: AC1MY8UN; Oprea1_240228; BenzylZ-|A-D-glucosaminide; benzyl2-{[(benzyloxy)carbonyl]amino}-2-deoxyhexopyranoside; benzylN-[4,5-dihydroxy-6-(hydroxymethyl)-2-phenylmethoxyoxan-3-yl]carbamate; 2862-10-4. Grades: 95%. CAS No. 2862-10-4. Molecular formula: C21H25NO7. Mole weight: 403.4257.
A-(BENZYLTHIO)ACETAMIDE
A-(BENZYLTHIO)ACETAMIDE. Alternative Names: A-(BENZYLTHIO)ACETAMIDE; 2-(Benzylthio)acetamide. Grades: 95%. CAS No. 54744-70-6. Molecular formula: C9H11NOS.
Abeprazan
Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is used for the treatment of 5-HT receptor or muscarinic acetylcholine receptor-mediated diseases. Alternative Names: Fexuprazan; 5-(2,4-Difluorophenyl)-1-[(3-fluorophenyl)sulfonyl]-4-methoxy-N-methyl-1H-pyrrole-3-methanamine; DWP14012; DWP-14012. Grades: 99%. CAS No. 1902954-60-2. Molecular formula: C19H17F3N2O3S. Mole weight: 410.41.
Abeprazan hydrochloride
Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is used for the treatment of 5-HT receptor or muscarinic acetylcholine receptor-mediated diseases. Alternative Names: DWP14012 hydrochloride; Fexuprazan hydrochloride. CAS No. 1902954-87-3. Molecular formula: C19H18ClF3N2O3S. Mole weight: 446.87.
ABERCHROME 670
ABERCHROME 670. Alternative Names: 2-(2-ADAMANTYLIDENE)-3-[1-(2,5-DIMETHYL-3-FURANYL)ETHYLIDENE]-SUCCINANHYDRIDE; ABERCHROME 670. Grades: 95%. CAS No. 94856-25-4. Molecular formula: C22H24O4. Mole weight: 352.42.
ABET
Arecaidine But-2-ynyl Ester Tosylate (ABET) is a potent and selective agonist of M2 recceptors in the atrium versus those in the ileum. Alternative Names: Arecaidine but-2-ynyl ester tosylate; N-Methyl-1'2'5'6-tetrahydropyridine-3-carboxylic acid but-2-ynyl ester tosylate. CAS No. 119630-77-2. Molecular formula: C18H23NO5S. Mole weight: 365.444.
Abexinostat
Abexinostat, also known as PCI-24781 or CRA-024781, is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling. Alternative Names: CRA-024781; CRA 024781; CRA024781; PCI-24781; PCI24781; PCI 24781. Grades: 98%. CAS No. 783355-60-2. Molecular formula: C21H23N3O5. Mole weight: 397.431.
ABH
ABH is an inhibitor of arginase types I and II. Alternative Names: Amino-2-borono-6-hexanoic acid; (S)-2-amino-6-boronohexanoic acid. Grades: ≥90%. CAS No. 222638-65-5. Molecular formula: C6H14BNO4. Mole weight: 175.
ABI-010
ABI-010 is the nanoparticle albumin-bound 17-AAG. Alternative Names: ABI-010; ABI 010; ABI010.
Abierixin
Abierixin is a polyether antibiotic isolated from Streptomyces albus NRRL B-1865. Abierixin exhibited weak antimicrobial and ionophorous activities, low toxicity but good anticoccidial activity. Alternative Names: Nigericin, 3,7-deepoxy-2,3-didehydro-7-hydroxy-; (2E)-7-hydroxy-8-(2-{5'-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl)-2,4-dimethyloct-2-enoic acid. CAS No. 100634-16-0. Molecular formula: C40H68O11. Mole weight: 724.96.
Abiesadine I
Abiesadine I is an eminent natural compound manifesting remarkable potential in studying diverse malignancies. Sourced from the Abies tree, this groundbreaking product orchestrates resolute antitumor mechanisms, specifically honed to assail malignant cells. E. Alternative Names: 4-[(15-Hydroxyabieta-8,11,13-trien-18-yl)oxy]-4-oxobutanoic acid. Grades: 96.0%. CAS No. 1210347-50-4. Molecular formula: C24H34O5. Mole weight: 402.52.
Abiesadine N
Abiesadine N is isolated from the barks of Pinus yunnanensis. Uses: Anti-inflammatory activity. Alternative Names: 15-Methoxyabieta-8,11,13-trien-18-oic acid. Grades: 97.5%. CAS No. 1159913-80-0. Molecular formula: C21H30O3. Mole weight: 330.5.
ABIES ALBA LEAF OIL
ABIES ALBA LEAF OIL. Alternative Names: ABIES ALBA LEAF OIL; ABIES PECTINATA OIL; Oils, silver fir; EUROPEANSILVERFIR; TEMPLINOIL; ABIESALBAOIL(CONES); ABIESALBAOILFROMCONES; ABIESALBACONEOIL. Grades: 95%. CAS No. 8021-27-0.
Abiesinol F
Abiesinol F isolated from the herbs of Abies ernestii. Alternative Names: 2''-epi-Abiesinol E. Grades: > 95%. CAS No. 1190070-91-7. Molecular formula: C30H22O10. Mole weight: 542.5.
Abieta-8,11,13-triene-7,15,18-triol
Abieta-8,11,13-triene-7,15,18-triol is a remarkable bioactive constituent sourced from botanical origins aiding in studying a multitude of ailments, encompassing cancer, inflammatory conditions and microbial assaults. Alternative Names: Abieta-8;18-triol;13-triene-7. Grades: 95.0%. CAS No. 337527-10-3. Molecular formula: C20H30O3. Mole weight: 318.4504.
Abietane
Abietane is a diterpene product found in Croton tricolor and Croton argyrophyllus. Alternative Names: (-)-Abietane; Phenanthrene, tetradecahydro-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aR,4bS,7S,8aS,10aS)-; (4aR,4bα,7α,8aβ,10aα)-Tetradecahydro-1,1,4a-trimethyl-7-(1-methylethyl)phenanthrene; 13α-Isopropylpodocarpane. Grades: ≥95%. CAS No. 19407-12-6. Molecular formula: C20H36. Mole weight: 276.50.
Abietatriene
Abietatriene is a diterpene product found in Pinus brutia var. eldarica and Prumnopitys andina. Alternative Names: Dehydroabietan; Phenanthrene, 1,2,3,4,4a,9,10,10a-octahydro-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)-; (4aS,10aS)-1,2,3,4,4a,9,10,10a-Octahydro-1,1,4a-trimethyl-7-isopropylphenanthrene; 8,11,13-Abietatriene; Abieta-8,11,13-triene; ar-Abietatriene; (4aS,10aS)-1,2,3,4,4a,9,10,10a-Octahydro-1,1,4a-trimethyl-7-(1-methylethyl)phenanthrene; Phenanthrene, 1,2,3,4,4a,9,10,10a-octahydro-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS-trans)-; Podocarpa-8,11,13-triene, 13-isopropyl-; (+)-Dehydroabietadiene; Abietane, dehydro-; Dehydroabietane. Grades: ≥95%. CAS No. 19407-28-4. Molecular formula: C20H30. Mole weight: 270.45.
Abietic acid
Abietic acid isolated from the herbs of Pinus massoniana. Uses: Anti-inflammation. Alternative Names: (1R,4AR,4BR,10AR)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,4B,5,6,10,10A-DECAHYDRO-PHENANTHRENE-1-CARBOXYLIC ACID. Grades: 0.95. CAS No. 514-10-3. Molecular formula: C20H30O2. Mole weight: 302.45.
Abietic Acid Diamylamine
Abietic Acid Diamylamine. Alternative Names: (1R,4aR,4bR,10aR)-1,2,3,4,4a,4b,5,6,10,10a-Decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic Acid Compd. with N-Pentyl-1-pentanamine; (1R,4aR,4bR,10aR)- 1,2,3,4,4a,4b,5,6,10,10a-Decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic Acid Compd. with N-Pentyl-1-pentanamine. CAS No. 881185-17-7. Molecular formula: C20H30O2·C9H21N. Mole weight: 302.45+(143.27).
Abietic acid glycerol ester. Alternative Names: Abietic acid glycerol ester; Glycerine ester of wood resin; Glycerol ester of rosin. CAS No. 8050-30-4. Molecular formula: C23H36O4. Mole weight: 376.52954.
ABIETIC ACID SODIUM SALT 85+%
ABIETIC ACID SODIUM SALT 85+%. CAS No. 14351-66-7. Molecular formula: C20H29NaO2. Mole weight: 324.43.
Abikoviromycin
Abikoviromycin is an antiviral antibiotic piperidine alkaloid produced by the bacteria Streptomyces abikoensis and Streptomyces rubescens. The dilution of Abikoviromycin has the effect of anti-Eastern and Western equine encephalitis virus, but has no effect on Venezuelan virus. Alternative Names: Latumcidin; Abicoviromycin; Cyclopent(b)oxireno(c)pyridine, 7-ethylidene-1a,2,3,7-tetrahydro-, (1aR,7E,7aS)-; Cyclopent(b)oxireno(c)pyridine, 7-ethylidene-1a,2,3,7-tetrahydro-, (1aR-(1aR*,7E,7aS*))-; Cyclopent(b)oxireno(c)pyridine, 7-ethylidene-1a,2,3,7-tetrahydro-, (E)-(1aS,7aR)-; Virocidin; (1aR,7E,7aS)-7-Ethylidene-1a,2,3,7-tetrahydrocyclopent[b]oxireno[c]pyridine. Grades: ≥90%. CAS No. 31774-33-1. Molecular formula: C10H11NO. Mole weight: 161.20.
Abil WE09
Abil WE09 is a liquid nonionic W/O emulsifier that is distinguished by high emulsifying and emulsion-stabilizing action. The extremely favourable usage characteristics are achieved by the combination of a polyglycerol fatty acid ester with a silicone surfactant, the characteristic of which is the polymeric and polyfunctional structure. Alternative Names: ABIL® WE 09; Polyglyceryl-4 Isostearate; Cetyl PEG/PPG-10/1 Dimethicone; Hexyl Laurate.
Abil WE 09
Abil WE 09. Grades: 95%. CAS No. 110734-66-2.
Abiraterone
Abiraterone blocks the synthesis of androgens by inhibiting CYP17A1. It is used to treat metastatic, castration-resistant prostate cancer. Uses: The treatment of metastatic, castration-resistant prostate cancer. Alternative Names: (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol; 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol; CB 7598; CB-7598; CB7598. Grades: >98%. CAS No. 154229-19-3. Molecular formula: C24H31NO. Mole weight: 349.51.
Abiraterone acetate
The acetate form of abiraterone, which blocks the synthesis of androgens by inhibiting CYP17A1. It can be used to treat metastatic, castration-resistant prostate cancer. Uses: The treatment of metastatic, castration-resistant prostate cancer. Alternative Names: CB7630; Zytiga; CB-7630; CB7630; Abiraterone (acetate). Grades: >98%. CAS No. 154229-18-2. Molecular formula: C26H33NO2. Mole weight: 391.55.
Abiraterone Acetate-5,6-Epoxide
Abiraterone Acetate-5,6-Epoxide is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Alternative Names: (3S,4aR,5aS,6aS,6bS,9aS,11aS,11bR)-9a,11b-dimethyl-9-(pyridin-3-yl)-1,2,3,4,5a,6,6a,6b,7,9a,10,11,11a,11b-tetradecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-3-yl acetate; (3β,5α,6α)-5,6-epoxy-17-(3-pyridinyl)-3-androst-16-en-3-ol-3-acetate. CAS No. 1868064-50-9. Molecular formula: C26H33NO3. Mole weight: 407.55.
Abiraterone Acetate-[d4]
Abiraterone Acetate-[d4] is a labelled form of Abiraterone Acetate, the acetate form of abiraterone, which blocks the synthesis of androgens by inhibiting CYP17A1. This compound is also useful in kinetic isotope effect studies as well as for use as an internal standard in NMR experiments. Alternative Names: (3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl-d4)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate; Abiraterone Acetate D4; Androsta-5,16-dien-3-ol, 17-(3-pyridinyl-2,4,5,6-d4)-, 3-acetate, (3β)-; Abiraterone Acetate-d4; (3β)-17-(3-pyridinyl-d4)-androsta-5,16-dien-3-ol, acetate ester. Grades: >95%; ≥99% atom D. CAS No. 2122245-63-8. Molecular formula: C26H29D4NO2. Mole weight: 395.58.
Abiraterone Acetate N-Oxide
Abiraterone Acetate N-Oxide is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Alternative Names: 3-((3S,8R,9S,10R,13S,14S)-3-acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine 1-oxide. CAS No. 2517964-85-9. Molecular formula: C26H33NO3. Mole weight: 407.55.
Abiraterone-[d4]
Abiraterone-[d4] is a labelled Abiraterone. Abiraterone is a steroidal CYP17A1 inhibitor with a therapeutic effect on androgen-dependent prostate cancer. Alternative Names: (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol-d4; CB 7598-d4. Grades: > 95%. CAS No. 2122245-62-7. Molecular formula: C24H27NOD4. Mole weight: 353.54.
Abiraterone Ethyl Ether
Abiraterone Ethyl Ether is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Alternative Names: 3-((3S,8R,9S,10R,13S,14S)-3-ethoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 2484719-14-2. Molecular formula: C26H35NO. Mole weight: 377.56.
Abiraterone Ethyl Ether-[d5]
Abiraterone Ethyl Ether-[d5] is the labelled impurity of Abiraterone. Abiraterone blocks the synthesis of androgens by inhibiting CYP17A1. It is used to treat metastatic, castration-resistant prostate cancer. Alternative Names: 3-((3S,8R,9S,10R,13S,14S)-3-ethoxy-d5-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grades: > 98%. Molecular formula: C26H30D5NO. Mole weight: 382.59.
Abiraterone isopropyl ether
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Alternative Names: 3-[3-(1-Methylethoxy)androsta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grades: ≥95%. CAS No. 2484719-15-3. Molecular formula: C27H37NO. Mole weight: 391.59.
Abiraterone Isopropyl Ether-[d7]
Abiraterone Isopropyl Ether-[d7] is the labelled impurity of Abiraterone. Abiraterone blocks the synthesis of androgens by inhibiting CYP17A1. It is used to treat metastatic, castration-resistant prostate cancer. Alternative Names: 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-d7-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grades: > 98%. Molecular formula: C27H30D7NO. Mole weight: 398.64.
Abiraterone Methyl Ether
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Alternative Names: 3-[(3β)-3-Methoxyandrosta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grades: ≥95%. CAS No. 1470276-23-3. Molecular formula: C25H33NO. Mole weight: 363.55.
Abiraterone O-β-D-glucuronide
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Alternative Names: Abiraterone O-beta-D-glucuronide; (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol β-D-Glucuronide. CAS No. 2307194-33-6. Molecular formula: C30H39NO7. Mole weight: 525.63.
Abiraterone propionate
Abiraterone propionate. CAS No. 1620323-43-4.
Abiraterone Related Compound 2
A related compound of Abiraterone. Alternative Names: (5α)-17-(3-Pyridinyl)androst-16-en-3-one; Abiraterone Impurity 2. Grades: > 95%. CAS No. 154229-26-2. Molecular formula: C24H31NO. Mole weight: 349.52.
Abiraterone Related Compound 3 (Pregnenolone-16-ene Acetate Oxime)
Pregnenolone-16-ene Acetate Oxime is used in the synthesis of pegnange derivatives as antioxidant and anti-dyslipidemic agents. Alternative Names: Abiraterone Impurity 3,Pregnenolone-16-ene Acetate Oxime. Grades: > 95%. CAS No. 2174-13-2. Molecular formula: C23H33NO3. Mole weight: 371.52.
Abiraterone Related Compound 4 (Prasterone Acetate Triflate)
An impurity of Abiraterone, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. Alternative Names: Abiraterone Impurity 4, Prasterone Acetate Triflate. Grades: > 95%. CAS No. 115375-60-5. Molecular formula: C22H29F3O5S. Mole weight: 462.53.
Abiraterone Related Compound 7
An impurity of Abiraterone , a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor. Alternative Names: Abiraterone Impurity 7. Grades: > 95%. Molecular formula: C47H61NO4. Mole weight: 704.01.
Abitesartan
Abitesartan. CAS No. 137882-98-5. Molecular formula: C26H31N5O3. Mole weight: 461.6.
Abituzumab
Abituzumab is a humanized anti-integrin αV monoclonal antibody developed for the treatment of prostate cancer metastatic. Abituzumab binds to αVβ3 and inhibits endothelial cell-cell interactions, endothelial cell-matrix interactions, and integrin-mediated tumor angiogenesis and metastasis in αVβ3-expressing tumor cells. Alternative Names: EMD 525797; DI17E6. CAS No. 1105038-73-0.
AbK
AbK is an unnatural amino acid and is genetically encoded for site-selective incorporation into proteins in mammalian cells and bacteria. It has efficient photocrosslinking in vitro and in vivo. It is used as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase / tRNACUA pairs. Alternative Names: N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine. Grades: ≥98% by HPLC. CAS No. 1253643-88-7. Molecular formula: C13H21N4O6F3. Mole weight: 272.30.
ABL 127
ABL 127 is a covalent aza-β-lactam inhibitor of protein phosphatase methylesterase-1 (PME-1; IC50 = 4.2 nM). Grades: ≥98%. CAS No. 1073529-41-5. Molecular formula: C17H20N2O5. Mole weight: 332.4.
Abl Cytosolic Substrate
Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl). Alternative Names: L-Lysine, L-α-glutamyl-L-alanyl-L-isoleucyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alanyl-L-lysyl-L-lysyl-; L-Lysine, N2-[N2-[N2-[N-[N-[1-[N-[N-[N-[N-(N-L-α-glutamyl-L-alanyl)-L-isoleucyl]-L-tyrosyl]-L-alanyl]-L-alanyl]-L-prolyl]-L-phenylalanyl]-L-alanyl]-L-lysyl]-L-lysyl]-; L-α-Glutamyl-L-alanyl-L-isoleucyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alanyl-L-lysyl-L-lysyl-L-lysine; Glu-Ala-Ile-Tyr-Ala-Ala-Pro-Phe-Ala-Lys-Lys-Lys. Grades: ≥95%. CAS No. 168202-46-8. Molecular formula: C64H101N15O16. Mole weight: 1336.58.
Abl Cytosolic Substrate acetate
Abl Cytosolic Substrate acetate is a substrate for Abelson tyrosine kinase (Abl). Alternative Names: Glu-Ala-Ile-Tyr-Ala-Ala-Pro-Phe-Ala-Lys-Lys-Lys acetate salt; L-α-Glutamyl-L-alanyl-L-isoleucyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alanyl-L-lysyl-L-lysyl-L-Lysine acetate salt. Grades: ≥95%. CAS No. 2918768-10-0. Molecular formula: C64H101N15O16.C2H4O2. Mole weight: 1396.63.
Ablukast
Ablukast, a specific and active leukotriene receptor antagonist, effectively reduces LTC4- and antigen-induced bronchoconstriction. It is an LTD4 receptor antagonist with anti-asthmatic effect. Alternative Names: Ro 23-3544; 6-Acetyl-7-(5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyloxy)-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid; 2H-1-Benzopyran-2-carboxylic acid, 6-acetyl-7-((5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl)oxy)-3,4-dihydro-, (±)-. Grades: ≥95%. CAS No. 96566-25-5. Molecular formula: C28H34O8. Mole weight: 498.56.
ABMA
ABMA is a broad-spectrum inhibitor of intracellular toxin and pathogens. It efficiently protects cells against various pathogens including viruses, intracellular bacteria, and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. Alternative Names: Adamantan-1-yl-(5-bromo-2-methoxy-benzyl)-amine; adamantanyl[(5-bromo-2-methoxyphenyl)methyl]amine. Grades: 99%. CAS No. 332108-65-3. Molecular formula: C18H24BrNO. Mole weight: 350.29.
AB-MECA
AB-MECA, a adenosine derivative, is a high affinity human A3 receptor in HEK 293 cells agonist. Alternative Names: (2S,3S,4R,5R)-5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamideABMECA; AB MECA; AB-MECA152918-26-8N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine(2S,3S,4R,5R)-5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxo. CAS No. 152918-26-8. Molecular formula: C18H21N7O4. Mole weight: 399.40.
a,b-Methyleneguanosine 5'-diphosphate sodium salt
a,b-Methyleneguanosine 5'-diphosphate sodium salt, as a fundamental chemical compound, finds wide applications in the biomedical sector due to its therapeutic potential across diverse diseases. With its significant contribution to vital cellular mechanisms and signal transduction pathways, this compound essentially facilitates the synthesis and metabolism of guanosine triphosphate, a pivotal molecule implicated in numerous biological processes. Alternative Names: GMPCP; GPCP. Molecular formula: C11H17N5O10P2·xNa. Mole weight: 441.23 (free acid).
Abn-CBD
Abn-CBD is a neurobehaviorally inactive cannabinoid and acts as a selective and potent agonist for GPR55 with EC50 value of 2.5 μM. It increases migration and phosphorylation of protein kinases in human umbilical vein endothelial cells. Alternative Names: 1,3-Benzenediol, 4-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-; 1,3-Benzenediol, 4-[3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-, trans-(-)-; 4-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol; Resorcinol, 4-p-mentha-1,8-dien-3-yl-5-pentyl-, trans-(-)-; Abnormal Cannabidiol; (1'R,2'R)-5'-methyl-6-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,4-diol; trans-(-)-4-p-Mentha-1,8-dien-3-yl-5-pentylresorcinol; trans-(-)-4-[3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol. Grades: ≥97% by HPLC. CAS No. 22972-55-0. Molecular formula: C21H30O2. Mole weight: 314.47.
ABP 688
ABP 688 is a high affinity human mGlu5 receptor antagonist (Ki = 1.7 nM) that inhibits the release of glutamate-induced calcium from L(tk-) cells expressing human mGlu5 receptors (IC50 = 2.3 nM). Alternative Names: ABP688; ABP-688; ABP 688; 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime; N-methoxy-3-[2-(6-methylpyridin-2-yl)ethynyl]cyclohex-2-en-1-imine. Grades: ≥98% by HPLC. CAS No. 924298-51-1. Molecular formula: C15H16N2O. Mole weight: 240.3.
Abrezekimab
Abrezekimab. CAS No. 2043952-59-4.
Abrilumab
Abrilumab is a human monoclonal antibody against α4β7, which is a validated target in inflammatory bowel disease. CAS No. 1342290-43-0.
ABRIN C
ABRIN C. CAS No. 53597-24-3.
abrineurin
abrineurin. Grades: 95%. CAS No. 178535-92-7.
Abrocitinib
Abrocitinib is a seletive JAK1 inhibitor with IC50 value of 29 nM. Abrocitinib has been investigated for the treatment of plaque psoriasis. Alternative Names: PF-04965842; N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide. Grades: >98%. CAS No. 1622902-68-4. Molecular formula: C14H21N5O2S. Mole weight: 323.415.
An a-bromo amides that inactivates a-chymotrypsin. Alternative Names: N-(Bromoacetyl)-N-methylbenzylamine; N-Methyl-N-benzyl-2-bromoacetamide; N-Methyl-N-benzylbromoacetamide. CAS No. 73391-96-5. Molecular formula: C10H12BrNO. Mole weight: 242.11.