BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester | Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Molecular formula: C33H46N6O10. Mole weight: 686.75. |  |
| Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine-[d4] | Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine-[d4] is the labelled analogue of Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine, which is a degradation product of Abacavir Sulfate, a nucleoside reverse transcriptase inhibitor (NRTI). Alternative Names: Abacavir-D4 5'-4-Chloro-6-methylpyrimidine-2,5-diamine; N6-Cyclopropyl-d4-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir-d4 Related Compound D. Molecular formula: C18H17D4ClN10O. Mole weight: 432.90. | |
| Abacavir 5'-β-D-Glucuronide | Abacavir 5'-β-D-Glucuronide is a metabolite of Abacavir, which is a nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Alternative Names: [(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopenten-1-yl]methyl β-D-glucopyranosiduronic acid; Abacavir 5'-Glucuronide. Grades: >95%. CAS No. 384329-76-4. Molecular formula: C20H26N6O7. Mole weight: 462.46. | |
| Abacavir 5'-Phosphate | A metabolite of Abacavir. Alternative Names: (1S,4R)- 4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Dihydrogen Phosphate (Ester); (1S-cis)-Abacavir Monophosphate. Grades: > 95%. CAS No. 136470-77-4. Molecular formula: C14H19N6O4P. Mole weight: 366.32. | |
| Abacavir CABS-1 Methyl Ester | Abacavir CABS-1 Methyl Ester, is an impurity of Abacavir (A105000), a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Alternative Names: Methyl (1S,4R)-4-(2-amino-6-chloro-5-formamidopyrimidin-4-yl)cyclopent-2-ene-1-carboxylate. Molecular formula: C12H14ClN5O3. Mole weight: 311.72. | |
| Abacavir CABS-2 methyl ester | Abacavir CABS-2 methyl ester. | |
| Abacavir Carboxylate | A major metabolite of Abacavir in human urine and cerebrospinal fluid. Alternative Names: (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid. Grades: > 95%. CAS No. 384380-52-3. Molecular formula: C14H16N6O2. Mole weight: 300.32. | |
| Abacavir-[d4] | Abacavir-[d4] is the labelled analogue of Abacavir, which is a nucleoside reverse transcriptase inhibitor. Alternative Names: Abacavir-d4; (1S,4R)-4-[2-Amino-6-(cyclopropylamino-d4)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1S-cis)-4-[2-Amino-6-(cyclopropylamino-d4)-9H-purin-9-yl]-2-cyclopentene-1-methanol; ABC-d4; Ziagen-d4. Grades: 97%; ≥95% atom D. CAS No. 1260619-56-4. Molecular formula: C14H14D4N6O. Mole weight: 290.36. | |
| Abacavir-[d5] | Labelled Abacavir. Abacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Alternative Names: [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol-d5. Molecular formula: C14H13D5N6O. Mole weight: 291.36. | |
| Abacavir Diamino Impurity | Abacavir Diamino Impurity. Alternative Names: Abacavir USP Related Compound B; Abacavir Deformylated CABS-1; (1S,4R)-4-[(2,5-Diamino-6-chloro-4-pyrimidinyl)amino]-2-cyclopentene-1-methanol; (1S,4R)-4-(2,5-Diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl]methanol); (1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)-cyclopent-1-methanol; 2-Cyclopentene-1-methanol, 4-((2,5-diamino-6-chloro-4-pyrimidinyl)amino)-, (1S,4R)-; 2-Cyclopentene-1-methanol, 4-[(2,5-diamino-6-chloro-4-pyrimidinyl)amino]-, (1S-cis)-; (+/-)-cis-4-[(2,5-Diamino-4-chloro-6-pyrimidinyl)amino]-2-cyclopentene-1-methanol; Abacavir Related Compound B; Abacavir Desformyl ABACA-1 Impurity. Grades: ≥95%. CAS No. 141271-12-7. Molecular formula: C10H14ClN5O. Mole weight: 255.70. | |
| Abacavir EP Impurity B | Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Alternative Names: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine; O-Pyrimidine derivative abacavir. CAS No. 1443421-69-9. Molecular formula: C18H21ClN10O. Mole weight: 428.88. | |
| Abacavir EP Impurity C | An impurity of Abacavir, a medication used to treat HIV. Alternative Names: (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentene-1-methanol; Descyclopropyl Abacavir. Grades: > 95%. CAS No. 124752-25-6. Molecular formula: C11H14N6O. Mole weight: 246.27. | |
| Abacavir EP Impurity D | An impurity of Abacavir, a medication used to treat HIV. Alternative Names: trans-Abacavir. CAS No. 783292-37-5. Molecular formula: C14H18N6O. Mole weight: 286.33. | |
| Abacavir EP Impurity E | An impurity of Abacavir, a medication used to treat HIV. Alternative Names: (1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol. CAS No. 208762-35-0. Molecular formula: C14H20N6O. Mole weight: 288.35. | |
| Abacavir EP Impurity F | An impurity of Abacavir, a medication used to treat HIV. Alternative Names: t-Butyl derivative abacavir; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl)-N6-cyclopropyl-9H-purine-2,6-diamine. Grades: > 95%. CAS No. 1443421-68-8. Molecular formula: C18H26N6O. Mole weight: 342.45. | |
| Abacavir Impurity 1 | A metabolite of Abacavir in human urine and cerebrospinal fluid. Alternative Names: 2-Cyclopentene-1-methanol, 4-(2-amino-6-chloro-7H-purin-7-yl)-, (1S-cis)- (9CI). Grades: > 95%. CAS No. 178327-20-3. Molecular formula: C11H14ClN5O. Mole weight: 267.72. | |
| Abacavir Impurity 2 | A metabolite of Abacavir in human urine and cerebrospinal fluid. Alternative Names: (1S,4R)-4-<(2',5'-diamino-6'-chloropyrimidin-4'-yl)amino>cyclopent-2-enylmethanol. Grades: > 95%. CAS No. 122624-77-5. Molecular formula: C10H14ClN5O. Mole weight: 255.71. | |
| Abacavir N-Oxide | An impurity of Abacavir, a medication used to treat HIV. Alternative Names: 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-7-oxido-9H-purin-9-yl]-, (1S,4R)-; Abacavir Impurity 19; Abacavir impurity N-Oxide; 2-Amino-6-(cyclopropylamino)-9-((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)-9H-purine 7-oxide; (1S,4R)-4-(2-Amino-6-(cyclopropylamino)-7-oxido-9H-purin-9-yl)-2-cyclopentene-1-methanol. Grades: ≥95%. CAS No. 1443421-70-2. Molecular formula: C14H18N6O2. Mole weight: 302.33. | |
| Abacavir sulfate | Abacavir is an antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC50 value of 5.3 μM. Alternative Names: 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1). Grades: ≥98%. CAS No. 216699-07-9. Molecular formula: C14H18N6O·H2SO4. Mole weight: 384.4. | |
| Abacavir Sulfate (2:1) | Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1. Abacavir is an analog of guanosine (a purine). Its target is the viral reverse transcriptase enzyme. Alternative Names: 1592U89. Grades: 95%. CAS No. 188062-50-2. Molecular formula: C14H18N6O.1/2H2O4S. Mole weight: 335.35. | |
| Abaecin | Abaecin is an antimicrobial peptide produced by Apis mellifera (Honeybee). It has antibacterial activity. Alternative Names: Tyr-Val-Pro-Leu-Pro-Asn-Val-Pro-Gln-Pro-Gly-Arg-Arg-Pro-Phe-Pro-Thr-Phe-Pro-Gly-Gln-Gly-Pro-Phe-Asn-Pro-Lys-Ile-Lys-Trp-Pro-Gln-Gly-Tyr-OH. Grades: >97%. CAS No. 123997-18-2. Molecular formula: C187H270N48O43. Mole weight: 3878.50. | |
| Abaecin 1 precursor | Abaecin 1 precursor is an antimicrobial peptide produced by Solenopsis invicta (Red imported fire ant). It has antimicrobial activity. Alternative Names: Gln-Pro-Pro-Ile-Arg-Asn-Pro-Pro-Pro-Gly-Gly-Trp-Lys-Pro-Phe-Pro-Thr-Phe-Pro-Gly-Gln-Gly-Pro-Tyr-Asn-Pro-Lys-Ile-Arg-Phe-Pro-His. Grades: ≥96%. | |
| Abaecin isoform 1 | Abaecin isoform 1 is an antimicrobial peptide produced by Bombus terrestris (Buff-tailed bumblebee). It has antimicrobial activity. Alternative Names: Val-Pro-Tyr-Asn-Pro-Pro-Arg-Pro-Gly-Gln-Ser-Lys-Pro-Phe-Pro-Thr-Phe-Pro-Gly-His-Gly-Pro-Phe-Asn-Pro-Lys-Thr-Gln-Trp-Pro-Tyr-Pro-Leu-Pro-Asn-Pro-Gly-His. Grades: 96%. | |
| Abaecin isoform 2 | Abaecin isoform 2 is an antimicrobial peptide produced by Bombus terrestris (Buff-tailed bumblebee). It has antimicrobial activity. Alternative Names: Pro-Pro-Arg-Pro-Gly-Gln-Ser-Lys-Pro-Phe-Pro-Thr-Phe-Pro-Gly-His-Gly-Pro-Phe-Asn-Pro-Lys-Thr-Gln-Trp-Pro-Tyr-Pro-Leu-Pro-Asn-Pro-Gly-His. Grades: ≥97%. | |
| Abaecin-like | Abaecin-like is an antimicrobial peptide produced by Bombus impatiens (Bumblebee). It has antimicrobial activity. Alternative Names: Pro-Pro-Arg-Pro-Gly-Gln-Ser-Lys-Pro-Phe-Pro-Ser-Phe-Pro-Gly-His-Gly-Pro-Phe-Asn-Pro-Lys-Ile-Gln-Trp-Pro-Tyr-Pro-Leu-Pro-Asn-Pro-Gly-His. Grades: ≥95%. | |
| abafungin | Abafungin is a broad-spectrum antifungal agent with a novel mechanism of action originated by York Pharma. In Aug 2009, Phase-III for Dermatomycoses in Japan and Europe was discontinued. At the same time, preclinical for Onychomycosis in United Kingdom was discontinued. Uses: Dermatomycoses; onychomycosis. Alternative Names: N-[4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl]-1,4,5,6-tetrahydropyrimidin-2-amine;Abafungin;BAY-W 6341;N-[4-[2-(2,4-Dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-2-pyrimidinamine. Grades: 95%. CAS No. 129639-79-8. Molecular formula: C21H22N4OS. Mole weight: 378.50. | |
| Abagovomab | Abagovomab is a murine IgG1 monoclonal anti-idiotype antibody that functionally imitates the tumor-associated antigen, CA-125. Abagovomab has been used in the research of ovarian cancer treatment. Alternative Names: Immunoglobulin G1, anti-(mouse oc 125) (mouse monoclonal aca-125 clone 3D5 gamma-chain), disulfide with mouse monoclonal aca-125 clone 3D5 kappa-chain, dimer. Grades: 95%. CAS No. 792921-10-9. | |
| Abaloparatide | Abaloparatide is an analogue of parathyroid hormone-related protein (PTHrP) which is used for the treatment of osteoporosis. In 28 April 2017, it was approved by FDA for the treatment of postmenopausal women with osteoporosis. Studies showed that abaloparatide could decrease the risk of new vertebral and nonvertebral fractures. Uses: The treatment of osteoporosis. Alternative Names: Tymlos. Grades: 98%. CAS No. 247062-33-5. Molecular formula: C174H300N56O49. Mole weight: 3960.58. | |
| Abaloparatide acetate | Abaloparatide acetate, an effective and selective activator of the PTHR1 signaling pathway, is an analog of parathyroid hormone-related protein (PTHrP) used for the treatment of osteoporosis. Alternative Names: H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2.CH3CO2H; L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysyl-glycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-leucyl-alpha-methyl-alanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide acetic acid. Grades: ≥95%. Molecular formula: C176H304N56O51. Mole weight: 4020.71. | |
| Abaloparatide TFA | Abaloparatide TFA is an analog of parathyroid hormone-related protein (PTHrP) used for the treatment of osteoporosis. Alternative Names: H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2.TFA; L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysyl-glycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-leucyl-alpha-methyl-alanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide trifluoroacetic acid; BIM 44058 trifluoroacetate; Eladynos trifluoroacetate. Grades: ≥95%. Molecular formula: C176H301N56F3O51. Mole weight: 4074.61. | |
| Abamectin | Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. It is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b, which have very similar biological and toxicological properties. Avermectin B1 is a natural fermentation product of this bacterium. Alternative Names: Avomec; Agri-Mek; Avid; Agrimek; Vertimec; Affirm; Zephyr; MK 936; MK 0936; NSC 758202; Avermectin B1; MK-936; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin B1 deriv.; A 14906; A 8612; Abamektin; Abamitel; Abarex; Abastate; Abastate EW; Abathor; Abba; Agador; AgMectin; Agri-Mek; Agri-Mek SC; Agrimec; Avermectin B1a-Avermectin B1b mixt.; Aversectin S; Avert; Avicta; Avicta 400FS; Avid 0.15EC; CHA 2061; CHA 2062; Dalamectin; Dalamektin; Epi-Mek; Fitoverm; Fitoverm M; Genesis Oral Drench; Genesis Pour-on for Cattle and Deer; Kraft; KRAFT 36 EC; L 676; Lirosect; Lyrosekt; Mectin; Phytoverm; PT 310; Rustomectin; STAN; Temprano; Vermitec; Vertigo (pesticide); Vertigo 018EC; Vertimec 018SC; Zoro. Grades: >95% a mixture of B1a and B1b. CAS No. 71751-41-2. Molecular formula: C48H72O14.C47H70O14. Mole weight: 1732.14. | |
| Abamectin EC | Abamectin EC. CAS No. 71751-41-4. | |
| Abamectin Tech | Abamectin Tech. CAS No. 71751-41-3. | |
| Abametapir | Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. Uses: 5,5'-dimethyl-2,2'-bipyridine is used in preparation of iron bipyridine acetoacetate complexes. Alternative Names: 5,5'-Dimethyl-2,2'-bipyridine; 6,6'-Bi-3-picoline; 5,5'-Dimethyl-2,2'-bipyridyl. Grades: 98 %. CAS No. 1762-34-1. Molecular formula: C12H12N2. Mole weight: 184.24. | |
| Abametapir-[d6] | Abametapir-[d6] is an isotopic labelled of Abametapir. Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases, enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. CAS No. 1803416-92-3. Molecular formula: C12H6D6N2. Mole weight: 190.27. | |
| Abanoquil mesilate | This molecular is an active biochemical as a Alpha 1 adrenergic receptor antagonist. However, no developments were reported for Ischaemic heart disorders and Arrhythmias. Uses: Arrhythmias; ischaemic heart disorders. Alternative Names: 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine;methanesulfonic acid,TCMDC-131968, TCMDC 131968, TCMDC131968, UK 52046; UK-52046; UK52046; Abanoquil. Grades: 98%. CAS No. 118931-00-3. Molecular formula: C23H29N3O7S. Mole weight: 491.56. | |
| Abaperidone | Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with IC50s of 6.2 and 17 nM, respectively. Alternative Names: 7-(3-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3-(hydroxymethyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(hydroxymethyl)-. Grades: 95%. CAS No. 183849-43-6. Molecular formula: C25H25FN2O5. Mole weight: 452.47. | |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Alternative Names: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grades: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. | |
| Abasic II phosphoramidite | Abasic II Phosphoramidite, a highly valuable chemical compound, plays a pivotal role in oligonucleotide synthesis, particularly in the context of medicinal applications, as it affords the unique ability to generate modified nucleic acids that combat cancer and genetic disorders. This innovative compound is exceedingly crucial in the biomedical sphere as it transforms the course of advanced therapeutics. Alternative Names: 5-O-Dimethoxytrityl-1-O-tert-butyldimethylsilyl-2-deoxyribose-3-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; α-D-erythro-Pentofuranose, 5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-1-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grades: ≥95%. CAS No. 1835233-43-6. Molecular formula: C41H59N2O7PSi. Mole weight: 750.98. | |
| Abatacept | Abatacept is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation modulator and a protein drug for the autoimmune diseases. Alternative Names: CTLA4lg. CAS No. 332348-12-6. | |
| Abbeymycin | Abbeymycin is an antibiotic isolated from the Streptomyces sp. AB-999F52. Abbeymycin has weak antibacterial activity against several anaerobic bacteria (such as Bacteroides fragilis, Bacteroides polymorpha, Peptococcus and Peptostreptococcus, etc.). Alternative Names: (2S,11S,11aS)-2-Hydroxy-11-methoxy-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; (2S)-2α-Hydroxy-11β-methoxy-1,2,3,10,11,11aβ-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2-hydroxy-11-methoxy-, (2S,11S,11aS)-; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2-hydroxy-11-methoxy-, (2S-(2-α,11-β,11a-β))-. Grades: 95%. CAS No. 108073-64-9. Molecular formula: C13H16N2O3. Mole weight: 248.28. | |
| Abbott 72517; Zankiren hydrochloride | Abbott 72517; Zankiren hydrochloride. CAS No. 138810-64-7. Molecular formula: C35H56ClN5O6S2. Mole weight: 742.4. | |
| ABBV-167 | ABBV-167 is a phosphate prodrug of venetoclax, a Bcl-2 inhibitor. Alternative Names: Benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-((7-((phosphonooxy)methyl)-7H-pyrrolo(2,3-b)pyridin-5-yl)oxy)-; (5-{5-(4-{[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-2-[({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)carbamoyl]phenoxy}-7H-pyrrolo[2,3-b]pyridin-7-yl)methyl dihydrogen phosphate. CAS No. 1351456-78-4. Molecular formula: C46H53ClN7O11PS. Mole weight: 978.45. | |
| ABBV-4083 | ABBV-4083 is an analog of Tylosin A and it has potent anti-Wolbachia and anti-filarial activities. Alternative Names: 4''-(p-Fluorobenzyl)tylosin A; Flubentylosin; 4b-O-((4-Fluorophenyl)methyl)tylosin. CAS No. 1809266-03-2. Molecular formula: C53H82FNO17. Mole weight: 1024.23. | |
| ABBV-744 | ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers. Alternative Names: N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide. Grades: ≥98%. CAS No. 2138861-99-9. Molecular formula: C28H30FN3O4. Mole weight: 491.55. | |
| ABBV-CLS-484 | ABBV-CLS-484 is a PTPN2 inhibitor under a Phase 1 clinical trial for the treatment of advanced solid tumors. Molecular formula: C17H24FN3O4S. Mole weight: 385.45. | |
| ABC-1183 | ABC-1183 is an inhibitor of glycogen synthase kinase 3 (GSK-3) alpha, glycogen synthase kinase 3 (GSK-3) beta and cyclin dependent kinase 9 (CDK-9). It can induce cell apoptosis and various signaling pathways. ABC-1183 shows toxicity to many cell lines in humans and mice. Alternative Names: ABC1183; ABC 1183; NSC797769; NSC-797769. Grades: > 99% by HPLC. CAS No. 1042735-18-1. Molecular formula: C18H14N4OS. Mole weight: 334.39. | |
| ABC294640 | ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. Alternative Names: ABC-294640; ABC294640; ABC 294640; Opaganib; 3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide. Grades: 0.98. CAS No. 915385-81-8. Molecular formula: C23H25ClN2O. Mole weight: 380.9104. | |
| ABC294735 | ABC294735 is a dual SK1/SK2 inhibitor with potential anticancer activity. Alternative Names: ABC-294735; ABC 294735. Grades: >98%. CAS No. 917236-13-6. Molecular formula: C24H26ClNO3. Mole weight: 411.92. | |
| ABC34 | ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). Alternative Names: 1,3-dioxo-7-(4-phenoxybenzyl)hexahydroimidazo[1,5-a]pyrazin-2(3H)-yl 4-(4-methoxyphenyl)piperazine-1-carboxylate. Grades: ≥98%. CAS No. 1831135-56-8. Molecular formula: C31H33N5O6. Mole weight: 571.6. | |
| ABC99 | ABC99 is an N-hydroxyhydantoin (NHH) carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM). It preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay). Grades: ≥95%. CAS No. 2331255-53-7. Molecular formula: C22H21ClN4O5. Mole weight: 456.9. | |
| ABCB1 | ABCB1, a CXC receptor ligand from the extracellular matrix (ECM), is produced during airway inflammation. Its activity links ECM degradation to neutrophil recruitment in airway inflammation. It may be a biomarker and therapeutic target for neutrophil inflammatory diseases. Alternative Names: Ac-PGP; Ac-Pro-Gly-Pro-OH; Acetyl Pro-Gly-Pro-OH; N-acetyl-L-prolyl-glycyl-L-proline; N-α-PGP. Grades: 95%. CAS No. 292171-04-1. Molecular formula: C14H21N3O5. Mole weight: 311.34. | |
| Abciximab | Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3, which binds to the platelet glycoprotein IIb / IIIa receptor and inhibits platelet aggregation. Alternative Names: ReoPro. Grades: 95%. CAS No. 143653-53-6. | |
| ABD459 | ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). Alternative Names: [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl](4-methoxyphenyl)-methanone. Grades: ≥95%. CAS No. 1047670-51-8. Molecular formula: C24H17BrCl2N2O2. Mole weight: 516.2. | |
| a:b-Diaminopropionic Acid Hydrochloride | a:b-Diaminopropionic Acid Hydrochloride. CAS No. 19391-83-4. Molecular formula: C3H8N2O2?HCl. Mole weight: 154.59. | |
| A B-DIBROMOCINNAMIC ACID | A B-DIBROMOCINNAMIC ACID. CAS No. 611-89-2. Molecular formula: C9H6Br2O2. Mole weight: 305.95. | |
| ABEI | It is a highly efficient chemiluminescent NH2-coupling reagent for detection of a wide variety of proteins, even up to the picomole range, and has significant advantages over traditional radioimmunoassays. Alternative Names: N-(4-Aminobutyl)-N-ethylisoluminol; 6-(N-(4-Aminobutyl)-N-ethyl)amino-2,3-dihydrophthalazine-1,4-dione; 4-(N1-Ethyl-4-aminobutylamino)phthalic hydrazide. Grades: ≥90%. CAS No. 66612-29-1. Molecular formula: C14H20N4O2. Mole weight: 276.33. | |
| ABEI-DSC | It is a highly efficient chemiluminescent COO-coupling reagent for detection of a wide variety of proteins, even up to the picomole range, and has significant advantages over traditional radioimmunoassays. Alternative Names: 2,5-dioxopyrrolidin-1-yl (4-((1,4-dioxo-1,2,3,4-tetrahydrophthalazin-6-yl)(ethyl)amino)butyl)carbamate. Grades: ≥95%. Molecular formula: C19H23N5O6. Mole weight: 417.42. | |
| Abelacimab | Abelacimab. CAS No. 2098724-83-3. | |
| Abemaciclib | Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: LY-2835219; LY 2835219; LY2835219; Verzenio; N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine. Grades: ≥98%. CAS No. 1231929-97-7. Molecular formula: C27H32F2N8. Mole weight: 506.61. | |
| Abemaciclib-[13C4,15N2] | Abemaciclib-[13C4,15N2] is a labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: N-(5-((4-ethylpiperazin-1-yl-2,3,5,6-13C4-1,4-15N2)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-[13C4,15N2]. Grades: ≥99% atom 13C; ≥98% atom 15N. Molecular formula: C23[13C]4H32F2N6[15N]2. Mole weight: 512.56. | |
| Abemaciclib-[d10] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-(methyl-d3)-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-(methyl-d3)-1-[1-(methyl-d3)ethyl-1,2,2,2-d4]-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY-2835219-d10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d10. Grades: >95%. CAS No. 2088650-71-7. Molecular formula: C27H22D10F2N8. Mole weight: 516.66. | |
| Abemaciclib-[d5] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d5; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d5. Grades: > 98%. CAS No. 1809251-51-1. Molecular formula: C27H27D5F2N8. Mole weight: 511.62. | |
| Abemaciclib-[d7] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d7. Grades: > 98%. Molecular formula: C27H25D7F2N8. Mole weight: 513.64. | |
| Abemaciclib-[d8] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: N-(5-((4-Ethylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D8; [d8]-Abemaciclib; [d8]-LY-2835219; LY-2835219-d8. Grades: ≥90%. CAS No. 2088650-53-5. Molecular formula: C27H24D8F2N8. Mole weight: 514.65. | |
| Abemaciclib Impurity 1-[d12] | Abemaciclib Impurity 1-[d12] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1h-benzo[d]imidazole-D12. Grades: > 98%. Molecular formula: C11D12BrFN2. Mole weight: 283.20. | |
| Abemaciclib Impurity 1-[d5] | Abemaciclib Impurity 1-[d5] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1h-benzo[d]imidazole-d5. Grades: > 98%. Molecular formula: C11H7D5BrFN2. Mole weight: 276.16. | |
| Abemaciclib Impurity 5-[d5] | Abemaciclib Impurity 5-[d5] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Alternative Names: 1-[(6-bromopyridin-3-yl)methyl]-4-ethylpiperazine-d5. Grades: > 98%. CAS No. 1809251-58-8. Molecular formula: C12H13D5BrN3. Mole weight: 289.23. | |
| abemaciclib mesylate | Abemaciclib mesylate is a CDK inhibitor with selectivity for CDK4 and CDK6. It was approved for the treatment of advanced or metastatic breast cancers. Uses: The treatment of advanced or metastatic breast cancers. Alternative Names: Verzenio; LY2835219; LY 2835219; LY-2835219; UNII-KKT462Q807; Abemaciclib methanesulfonate; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate. CAS No. 1231930-82-7. Molecular formula: C28H36F2N8O3S. Mole weight: 602.706. | |
| Abemaciclib metabolite M18 hydrochloride | Abemaciclib metabolite M18 (LSN3106729) hydrochloride, derived from Abemaciclib, is an antitumor CDK inhibitor. It has been utilized alongside a CRBN ligand to design a PROTAC CDK4/6 degrader. Molecular formula: C25H29ClF2N8O. Mole weight: 531. | |
Our database is helping our users find suppliers everyday.
