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4β-Hydroxywithanolide E
4β-Hydroxywithanolide E, isolated from Physalis peruviana L., inhibits adipocyte differentiation of 3T3-L1 cells through modulation of mitotic clonal expansion. 4β-Hydroxywithanolide E is an adipogenesis inhibitor and inhibits PPARγ, C/EBPα, and the adipocyte-specific molecule aP2 mRNA expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 54334-04-2. Pack Sizes: 1 mg. Product ID: HY-N7661.
4-Bromo-2,6-difluorobenzaldehyde
4-Bromo-2,6-difluorobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 537013-51-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-Y1747.
4-Bromo-7-azaindole
4-Bromo-7-azaindole is a brominated derivative of 7-azaindole. 4-Bromo-7-azaindole serves as a substrate for palladium-catalyzed C-N and C-O cross-coupling reactions, reacting with amides, amines, amino acid esters and phenols[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 348640-06-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-30014.
4-(Carboxymethyl)phenylboronic acid pinacol ester
4-(Carboxymethyl)phenylboronic acid pinacol ester is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 797755-07-8. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W000969.
4-Chloro-3-(2,4-dioxo-1,3-diazinan-1-yl)benzoic acid is an E3 ligase ligand that can be used in the recruitment of CRBN protein. 4-Chloro-3-(2,4-dioxo-1,3-diazinan-1-yl)benzoic acid can used to synthesis of PROTAC SOS1 degrader-4 (HY-153674) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2377645-90-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W115490.
4-Chloro-α-cyanocinnamic acid
4-Chloro-α-cyanocinnamic acid (Cl-CCA) is an advanced, rationally designed MALDI (Matrix-assisted laser desorption ionization) matrix[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cl-CCA. CAS No. 20374-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W755338.
4-Chlorobenzoic acid
4-Chlorobenzoic acid is a halogenated aromatic compound that can be used as an industrial chemical and an intermediate in drug synthesis. 4-Chlorobenzoic acid is a persistent organic micropollutant and can be biodegraded through a direct dehalogenation pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 74-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 250 g; 500 g. Product ID: HY-41465.
4-Chlorobutan-1-amine hydrochloride
4-Chlorobutan-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 6435-84-3. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W105713.
4-CMTB
4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 300851-67-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1125.
4-CPPC
4-CPPC is a potent, reversible and selective MIF-2 inhibitor with Ki values of 431, 33 μM for MIF-1, MIF-2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 29553-70-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123814.
4-Demethylnobiletin
4-Demethylnobiletin is a bioactive metabolite that activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and reverses memory impairment associated with NMDA receptor antagonism by stimulating ERK signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 34810-62-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-142066.
4-Deoxypyridoxine hydrochloride
4-Deoxypyridoxine (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Deoxypyridoxine hydrochloride. CAS No. 148-51-6. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g. Product ID: HY-W015210.
4-Di-10-ASP
4-Di-10-ASP is a fluorescent lipophilic tracer (Excitation 485 nm; Emission 620 nm). 4-Di-10-ASP can be used to stain phospholipid membranes in a specific manner[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 95378-73-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1630.
4-Di-2-ASP
4-Di-2-ASP, a styryl pyridinium fluorescent dye, is a vital mitochondrial marker. 4-Di-2-ASP shows reliable and specific labelling of pulmonary NEBs (neuroepithelial bodies)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 105802-46-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-D0060.
4-Diethylaminobenzaldehyde
4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 120-21-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W016645.
4-Dihydrophaseic acid
4-Dihydrophaseic acid is a metabolite of the plant hormone abscisic acid and is present in legume seeds[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 41756-77-8. Pack Sizes: 1 mg. Product ID: HY-116831.
4-Dimethylaminopyridine
4-Dimethylaminopyridine is an acyl transfer catalyst. 4-Dimethylaminopyridine is used for labeling and analysis of glycoproteins on the surface of living cells. 4-Dimethylaminopyridine reduces dyskinesia attacks[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1122-58-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 250 g; 500 g; 1 k g. Product ID: HY-Y1089.
4-Dimethylaminopyridine N-oxide
4-Dimethylaminopyridine N-oxide (p-Dimethylaminopyridine N-oxide) is an Efficient Oxidizing Agent for Alkyl Halides[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Dimethylaminopyridine N-oxide. CAS No. 1005-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W145090.
4-DTMP
4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFRWT) and 34.3 nM (DHFRL28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21253-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg. Product ID: HY-W587663.
4E1RCat
4E1RCat is an inhibitor of cap-dependent translation, and inhibits eIF4E:eIF4GI interaction, with an IC50 an of ~4 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 328998-25-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14427.
4EGI-1
4EGI-1 is an inhibitor of eIF4E/eIF4G interaction, with a Kd of 25 μM against eIF4E binding. Uses: Scientific research. Category: Signaling pathways. CAS No. 315706-13-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19831.
4-Ethylcatechol
4-Ethylcatechol is a ring-dihydroxylated metabolite of 4-Ethylphenol that leads to oxidative DNA damage[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1124-39-6. Pack Sizes: 250 mg; 1 g; 5 g; 10 g. Product ID: HY-W265757.
4-Ethynylbenzoic acid
4-Ethynylbenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 10602-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-W007533.
4-Ethynylcyclohexanone
4-Ethynylcyclohexanone is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1549050-50-1. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W089262.
4'-Fluoroacetophenone
4'-Fluoroacetophenone (1-(4-Fluorophenyl)ethan-1-one) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4'-Fluoroacetophenone is also an important intermediate that can be used in the synthesis of other active compounds, such as aromatic diketones[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-(4-Fluorophenyl)ethan-1-one. CAS No. 403-42-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g; 1 k g. Product ID: HY-Y0779.
4-Guanidinobutanoic acid
4-Guanidinobutanoic acid is a common urinary metabolite and arginine metabolite. 4-Guanidinobutanoic acid can be used in the research of fibromyalgia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 463-00-3. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-113286.
4-Hydroperoxy cyclophosphamide
4-Hydroperoxy cyclophosphamide is the active metabolite form of the precursor Cyclophosphamide. 4-Hydroperoxy cyclophosphamide cross-links DNA to induce T cell apoptosis independent of caspase receptor activation, and can activate the mitochondrial death pathway by producing reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide can be used in the study of rheumatoid arthritis and autoimmune diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39800-16-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117433.
4-Hydroperoxyifosfamide
4-Hydroperoxyifosfamide is an anticancer agent that can penetrate the blood-brain barrier (BBB)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39800-28-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134228.
4-Hydroxy-1H-indole-3-carbaldehyde
4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Hydroxyindole-3-carboxaldehyde. CAS No. 81779-27-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W091541.
4-Hydroxy-3-methoxyphenylglycol sulfate potassium
4-Hydroxy-3-methoxyphenylglycol sulfate potassium is a biosynthesis product that releases Na2SO4 and free ethylene glycol on acidic hydrolysis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MHPG sulfate potassium. CAS No. 71324-20-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113441.
4-Hydroxybenzoic acid
4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. Uses: Scientific research. Category: Signaling pathways. CAS No. 99-96-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-Y0264.
4-Hydroxybenzoic acid-13C6
4-Hydroxybenzoic acid-13C6 is the 13C labeled isotope of 4-Hydroxybenzoic acid-13C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL. Uses: Scientific research. Category: Signaling pathways. CAS No. 287399-29-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-Y0264S.
4-Hydroxybenzoic acid-d4
4-Hydroxybenzoic acid-d4 is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. Uses: Scientific research. Category: Signaling pathways. CAS No. 152404-47-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0264S1.
4-Hydroxybenzyl alcohol (Standard)
4-Hydroxybenzyl alcohol (Standard) is the analytical standard of 4-Hydroxybenzyl alcohol. This product is intended for research and analytical applications. 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 623-05-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-Y0892R.
4-Hydroxychalcone
4-Hydroxychalcone is an orally active flavonoid precursor. 4-Hydroxychalcone inhibits VEGF- and bFGF-induced phosphorylation of ERK1/2 and Akt. 4-Hydroxychalcone suppresses resistant hypertension by alleviating hyperaldosteronism, inflammation and renal injury in cryptochrome gene knockout mice. 4-Hydroxychalcone possesses anti-angiogenic activity[1][2].\n
. Uses: Scientific research. Category: Signaling pathways. CAS No. 20426-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-107818.
4-Hydroxyderricin
4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation[1]. 4-Hydroxyderricin is promising for research of inflammatory diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55912-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N7204.
4'-Hydroxy diclofenac
4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 64118-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-15550.
4'-Hydroxy diclofenac-13C6
4'-Hydroxy diclofenac-13C6 is the 13C labeled 4'-Hydroxy diclofenac[1]. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1189656-64-1. Pack Sizes: 1 mg. Product ID: HY-15550S1.
4'-Hydroxy diclofenac-d4
4'-Hydroxy diclofenac-d4 is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 254762-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-15550S.
4-Hydroxyestradiol
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Hydroxy-17β-estradiol. CAS No. 5976-61-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10403.
4'-Hydroxy flurbiprofen
4'-Hydroxy flurbiprofen is an oxidative metabolite of Flurbiprofen (HY-10582) via the cytochrome P450 enzyme system. 4'-Hydroxy flurbiprofen inhibits COX-1 by 94% at a concentration of 1000 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52807-12-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-118133.
4-Hydroxy Flurbiprofen-d3
4-Hydroxy Flurbiprofen-d3 is the deuterium labeled 4-Hydroxy Flurbiprofen[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1189694-02-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-132436S.
4-Hydroxyhippuric acid
4-Hydroxyhippuric acid is a metabolite of polyphenols. 4-Hydroxyhippuric acid is generated via medium-chain acyl-CoA dehydrogenase (MCAD)-dependent β-oxidation of microbially-produced 3-(4-hydroxyphenyl)propionic acid, followed by host glycine conjugation. 4-Hydroxyhippuric acid can be simultaneously detected in urine as a biomarker of dietary polyphenol intake[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2482-25-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-113158.
4-Hydroxyindole-3-acetic acid
4-Hydroxyindole-3-acetic acid (4HIAA) is a metabolite of Psilocybin and Psilocin[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4HIAA. CAS No. 56395-08-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W509381.
4-Hydroxymephenytoin
4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate. Uses: Scientific research. Category: Signaling pathways. CAS No. 61837-65-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008772.
4-Hydroxymephenytoin-d3
4-Hydroxymephenytoin-d3 is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1173022-56-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W008772S.
4-Hydroxymethyl-4'-methyl-2,2'-bipyridyl
4-Hydroxymethyl-4'-methyl-2,2'-bipyridyl (4'-Methyl-2,2'-bipyridine-4-methanol) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4'-Methyl-2,2'-bipyridine-4-methanol. CAS No. 81998-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W034582.
4-(Hydroxymethyl)benzoic acid
4-(Hydroxymethyl)benzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 3006-96-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g. Product ID: HY-W017384.
4-Hydroxynonenal
4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-HNE. CAS No. 75899-68-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113466.
4-Hydroxyphenylacetic acid-d6
4-Hydroxyphenylacetic acid-d6 is the deuterium labeled 4-Hydroxyphenylacetic acid. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 100287-06-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1902S.
4-Hydroxyphenylacetylglutamic acid
4-Hydroxyphenylacetylglutamic acid is a metabolite of Morus alba L[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1029120-37-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-180768.
4-Hydroxyphenylglyoxylate
4-Hydroxyphenylglyoxylate (4-Hydroxyphenylglyoxylic acid) is an inhibitor of carnitine palmitoyltransferase I (CPT I). 4-Hydroxyphenylglyoxylate can be used to study sensitivity changes in CPT I of liver mitochondria and fatty acid oxidation by isolated hepatocytes. 4-Hydroxyphenylglyoxylate can inhibits fatty acid oxidation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Hydroxyphenylglyoxylic acid; 4-HPGA. CAS No. 15573-67-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W104819.
4-?Hydroxyphenylpyruvic acid
4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine. 4-Hydroxyphenylpyruvic acid is a substrate of 4-hydroxyphenylpyruvic acid dioxygenase (HPPA). 4-Hydroxyphenylpyruvic acid can be used in the study of HPD-related diseases, such as type III tyrosinemia and hawkinsinuria[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 156-39-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-W010040.
4-Hydroxypropranolol-d7 hydrochloride
4-Hydroxypropranolol-d7 (hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency comparable to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-4-Hydroxy Propranolol-d7 hydrochloride. CAS No. 1219804-03-1. Pack Sizes: 1 mg. Product ID: HY-100634S.
4-Hydroxypropranolol hydrochloride
4-Hydroxypropranolol hydrochloride is a non-cardiac selective β-adrenergic receptor antagonist and a metabolite produced after oral administration of Propranolol (HY-B0573B). 4-Hydroxypropranolol hydrochloride also acts as a membrane stabilizer and possesses intrinsic sympathomimetic inhibitory activity. 4-Hydroxypropranolol hydrochloride blocks β-adrenergic receptors to antagonize the effects of catecholamines, acts as a partial β-adrenergic receptor agonist, and induces membrane stabilization. 4-Hydroxypropranolol hydrochloride alters heart rate, left ventricular contractility, and atrioventricular conduction time. 4-Hydroxypropranolol hydrochloride can be used in research related to cardiovascular and cerebrovascular diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-4-hydroxy Propranolol hydrochloride. CAS No. 14133-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-100634.
4-Hydroxypyridine-2,6-dicarboxylic acid
4-Hydroxypyridine-2,6-dicarboxylic acid is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Helidaminic acid. CAS No. 499-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W110147.
4-Hydroxytamoxifen
4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is an orally active, selective estrogen receptor modulator (SERM). 4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is also the active metabolic form of Tamoxifen (HY-13757A) in vivo and can be used to induce gene knockout in transgenic mice expressing CreER[1][2][3][4]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: (Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen; (Z)-Afimoxifene. CAS No. 68047-06-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16950.
4-Hydroxytolbutamide
4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroxytolbutamide. CAS No. 5719-85-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-100641.
4-Hydroxytolbutamide-d9
4-Hydroxytolbutamide-d9 is the deuterium labeled 4-Hydroxytolbutamide. 4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroxytolbutamide-d9. CAS No. 1185112-19-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-100641S.
4-IPP
4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Iodo-6-phenylpyrimidine. CAS No. 41270-96-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110063.
4-Isopropylbenzoic acid
4-Isopropylbenzoic acid (Cuminic acid; p-Isopropyl benzoic acid) an aromatic monoterpenoid, is isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid exhibits antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive inhibitor of mushroom tyrosinase[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cuminic acid; p-Isopropyl benzoic acid. CAS No. 536-66-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W013571.
4-Methoxybenzaldehyde
4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123-11-5. Pack Sizes: 50 g; 100 g; 500 g; 1 k g. Product ID: HY-Y0740.
4-Methoxyestradiol
4-Methoxyestradiol is methoxylestradiol that induces oxidative DNA damage in human lung epithelial cells. 4-Methoxyestradiol also elevates ROS and SOD activities in H1355 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26788-23-8. Pack Sizes: 1 mg. Product ID: HY-148296.
4-Methyl-2-oxopentanoic acid
4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to cognitive deficits, inhibits α-ketoglutarate dehydrogenase activity, acts as an oxidative phosphorylation uncoupler and metabolic inhibitor. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis. 4-Methyl-2-oxopentanoic acid can be used in the study of maple syrup urine disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Ketoisocaproic acid. CAS No. 816-66-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-W012722.
4-(Methylamino)butan-1-ol
4-(Methylamino)butan-1-ol (4-Methylamino butanol) is a kind of biological materials or organic compounds that are widely used in life science research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Methylamino butanol. CAS No. 42042-68-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W006493.
4-Methylbenzohydrazide
4-Methylbenzohydrazide (p-ToluoylHYdrazine) (Compound 5) is an antibacterial agent. 4-Methylbenzohydrazide shows a pMIC value of 1.38 against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Aspergillus niger[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Toluoylhydrazine. CAS No. 3619-22-5. Pack Sizes: 25 g; 50 g; 100 g; 500 g. Product ID: HY-W038767.
4-Methylhistamine dihydrochloride
4-Methylhistamine hydrochloride is the dihydrochloride salt of 4-Methylhistamine (HY-W580721). 4-Methylhistamine hydrochloride is a potent and selective agonist of histamine 4 receptor (H4R) with a Ki of 50 nM. 4-Methylhistamine hydrochloride has a >100-fold selectivity for the hH4R over the other histamine receptor subtypes. 4-Methylhistamine hydrochloride can potently activate the hH4R (pEC50 = 7.4). 4-Methylhistamine hydrochloride can be used for the researches of cancer, inflammation and immunology, such as lung cancer and skin inflammation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 36376-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-107560.
4-Methylmorpholine N-oxide
4-Methylmorpholine N-oxide (N-Methylmorpholine N-Oxide; MMNO; 4-Methylmorpholine 4-oxide) is an amine oxide ligand and ozonation reagent. 4-Methylmorpholine N-oxide forms coordination complexes with lanthanum (III) nitrate and yttrium (III) nitrate via its nitroso oxygen atom. The metal-ligand bonds are dominated by electrostatic interactions with a small covalent component. 4-Methylmorpholine N-oxide is applicable in ozonation reactions for the synthesis of methyl 9-oxononanoate[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Methylmorpholine N-Oxide; MMNO; 4-Methylmorpholine 4-oxide. CAS No. 7529-22-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y1101B.
4-Methylumbelliferone
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects. Uses: Scientific research. Category: Natural products. Alternative Names: Hymecromone; 4-MU. CAS No. 90-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-N0187.