MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| 6-Aminonicotinamide | 6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329-89-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-W010342. |  |
| 6-Azido-6-deoxy-D-galactose, 95% | 6-Azido-6-deoxy-D-galactose, 95% can be used as a substrate in enzymology to study the activity and specificity of galactosyltransferases and other glycosylation enzymes. Uses: Scientific research. Category: Signaling pathways. CAS No. 66927-03-5. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg. Product ID: HY-W718137. | |
| 6-Azido-6-deoxy-D-glucose, 95% | 6-Azido-6-deoxy-D-glucose, 95% is used for visualizing protein-specific glycosylation in living cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 20847-05-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W674039. | |
| 6-Azidohexanoic acid | 6-Azidohexanoic acid is an ester product. Uses: Scientific research. Category: Signaling pathways. CAS No. 79598-53-1. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-W123015. | |
| 6-Azido-hexylamine | 6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 6-Azido-hexylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 349553-73-7. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-138387. | |
| 6-Azuridine | 6-Azuridine (6-Azauridine) is an orally active purine nucleoside analogue. 6-Azuridine activates autophagic flux, induces Apoptosis that depends on AMPK and p53. 6-Azuridine exhibit both antitumor and antiviral activities[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Azauridine. CAS No. 54-25-1. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg; 1 g; 5 g; 25 g. Product ID: HY-131611. | |
| 6-Benzylaminopurine | 6-Benzylaminopurine (Benzyladenine) is a cytokinin that causes plant growth and development by stimulating cell division and inhibiting respiratory kinases, thereby prolonging the preservation of green vegetables[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Benzyladenine; 6-BAP; N6-Benzyladenine. CAS No. 1214-39-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-B0941. | |
| 6-Benzylaminopurine-d5 | 6-Benzylaminopurine-d5 is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Benzyladenine-d5; 6-BAP-d5; N6-Benzyladenine-d5. CAS No. 2322358-20-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0941S. | |
| 6β-Hydroxy Cortisol-d4 | 6β-Hydroxy Cortisol-d4 is a deuterium labeled compound. Uses: Scientific research. Category: Signaling pathways. CAS No. 1261254-51-6. Pack Sizes: 1 mg. Product ID: HY-W587724S. | |
| 6-Biopterin | 6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Biopterin. CAS No. 22150-76-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102015. | |
| 6bK TFA | 6bK TFA is a selective insulin-degrading enzyme (IDE) inhibitor with an IC50 of 50 nM. 6bK TFA binds to the distal pocket of IDE, thereby blocking substrate binding, peptide unfolding and cleavage processes, and reducing the degradation of insulin, glucagon and amylin. 6bK TFA improves oral glucose tolerance but impairs intraperitoneal glucose tolerance. 6bK TFA can be used in research related to type 2 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1774353-12-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-110197. | |
| 6-Bnz-cAMP sodium salt | 6-Bnz-cAMP sodium, a derivative of cyclic adenosine monophosphate (cAMP), is a selective PKA activator with inhibitory activity against the bTREK-1 K+ channel. 6-Bnz-cAMP sodium does not activate the Epac signaling pathway. It inhibits the bTREK-1 K+ channel via a voltage-independent, ATP-dependent mechanism that is independent of the PKA/Epac/calmodulin kinase/MAP kinase pathway. 6-Bnz-cAMP sodium activates CREB phosphorylation to regulate osteoblast-specific gene expression, induces osteoblast differentiation, promotes extracellular matrix mineralization, supports osteoblast proliferation, and shows no cytotoxicity toward osteoblasts. It can be used in studies related to bone tissue repair and regeneration[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135306-29-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-103322. | |
| 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine | 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 52287-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-W002191. | |
| 6-Bromo-L-tryptophan | 6-Bromo-L-tryptophan (6BrW) is a compound that can be incorporated into recombinant proteins by a specific system in bacterial cells, causing a blue shift in fluorescence emission and absorption maxima. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6BrW. CAS No. 52448-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-20899. | |
| 6-Chloro-7-deazaguanine | 6-Chloro-7-deazaguanine is an inactive molecule of IKK (lacking the critical 5-cyano group). IKKβ and IKKα are core molecules in the canonical NF-κB pathway and non-canonical NF-κB pathway, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 84955-31-7. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g. Product ID: HY-69047. | |
| 6-Chloro-7-hydroxy-4-methylcoumarin | 6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) an intermediate of pharmaceutical synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19492-02-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-128416. | |
| 6-Dehydrogingerdione | 6-Dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76060-35-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N7152. | |
| 6-Diazo-5-oxo-L-nor-Leucine | 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-6-Diazo-5-oxonorleucine; DON. CAS No. 157-03-9. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108357. | |
| 6-(Dimethylamino)purine | 6-(Dimethylamino) purine (6-Dimethylaminopurine) is a serine threonine protein kinase inhibitor. 6-(Dimethylamino) purine can inhibit prolactin induced expression of lactoprotein genes in rabbit mammary gland cells. 6-(Dimethylamino) purine can affect the maturation of mammalian oocytes. 6-(Dimethylamino) purine can lead to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induce apoptosis in lymphoma cells (apoptosis)[1][3][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Dimethylaminopurine; 6-DMAP. CAS No. 938-55-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-W010128. | |
| 6-FAM | 6-FAM (6-Carboxyfluorescein) is an isomer of carboxyfluorescein and is mainly used for sequencing and labeling of nucleic acids. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Carboxyfluorescein. CAS No. 3301-79-9. Pack Sizes: 25 mg; 100 mg; 500 mg. Product ID: HY-66021. | |
| 6-FAM-PEG3-Azide | 6-FAM-PEG3-Azide is a fluorescent dye that can be used to label oligonucleotide[1]. 6-FAM-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 412319-45-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135835. | |
| 6-FAM SE | 6-FAM SE (6-carboxyfluorescein succinimidyl ester) is a fluorescent labeling reagent. 6-FAM SE is used for oligonucleotide labeling and DNA sequencing[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92557-81-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15939. | |
| 6'''-Feruloylspinosin | 6'''-Feruloylspinosin is a flavonoid isolated from seeds of Ziziphus jujuba. 6'''-Feruloylspinosin can across the blood-brain barrier and enhance the expression of GABAAα1, GABAAα5, and GABABR1 mRNA in rat hippocampal neurons[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77690-92-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N2160. | |
| [6]-Gingerol | [6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-(+)-[6]Gingerol. CAS No. 23513-14-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14615. | |
| [6]-Gingerol (Standard) | [6]-Gingerol (Standard) is the analytical standard of [6]-Gingerol. This product is intended for research and analytical applications. [6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-(+)-[6]Gingerol (Standard). CAS No. 23513-14-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14615R. | |
| 6-Hexadecanoylamino-4-methylumbelliferyl β-D-galactopyranoside | 6-Hexadecanoylamino-4-methylumbelliferyl β-D-galactopyranoside is a specific fluorescent substrate with the function of detecting galactosidase activity. 6-Hexadecanoylamino-4-methylumbelliferyl β-D-galactopyranoside can be used in biomedical research to observe the efficiency of enzyme-catalyzed reactions. 6-Hexadecanoylamino-4-methylumbelliferyl β-D-galactopyranoside is also widely used in the analysis of polysaccharides and carbohydrate enzymology. Uses: Scientific research. Category: Signaling pathways. CAS No. 94452-17-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W777640. | |
| 6-Hydroxybentazon | 6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Hydroxybentazone. CAS No. 60374-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-100052. | |
| 6-Hydroxy Chlorzoxazone | 6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1750-45-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-W016221. | |
| 6-Hydroxy-DOPA | 6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21373-30-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110286. | |
| 6-Hydroxykaempferol 3,6-diglucoside | 6-Hydroxykaempferol 3,6-diglucoside possesses antiplatelet aggregatory effect[1]. Uses: Scientific research. Category: Natural products. CAS No. 142674-16-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125323. | |
| 6-Hydroxyluteolin | 6-Hydroxyluteolin (Compound 17) is a flavonoid derivative and also an inhibitor of Aldose reductase, with an experimental -log IC50 value of 6.690. 6-Hydroxyluteolin can be isolated from the leaves of multiple plant families, including Plantaginaceae, Globulariaceae and Labiatae. 6-Hydroxyluteolin serves as a phylogenetic marker for higher plants. 6-Hydroxyluteolin can be used in the research of diabetic cataract[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18003-33-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151231. | |
| 6-Hydroxymelatonin | 6-Hydroxymelatonin is the main metabolite of melatonin (HY-B0075) after being metabolized by CYP1A2 and can cross the blood-brain barrier. 6-Hydroxymelatonin has strong free radical scavenging ability and antioxidant activity, and can alleviate oxidative damage caused by various neurotoxins. 6-Hydroxymelatonin can cause oxidative DNA damage in the presence of copper ions through a "non-quinone" type redox cycling mechanism[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2208-41-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011956. | |
| 6-Hydroxy Melatonin-d4 | 6-Hydroxy Melatonin-d4 is the deuterium labeled 6-Hydroxy Melatonin[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 69533-61-5. Pack Sizes: 1 mg. Product ID: HY-132425S. | |
| 6-Hydroxyrubiadin | 6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases[1]. Uses: Scientific research. Category: Natural products. CAS No. 87686-86-0. Pack Sizes: 10 mg; 25 mg; 1 mg; 5 mg. Product ID: HY-N2714. | |
| 6-Ketocholestanol | 6-Ketocholestanol is a recoupler for mitochondria, chromatophores and cytochrome oxidase proteoliposomes. 6-Ketocholestanol increases the membrane dipole potential[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3β-Hydroxy-5α-cholestan-6-one. CAS No. 1175-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N9608. | |
| 6-Maleimidocaproic acid hydrazide TFA | 6-Maleimidocaproic acid hydrazide TFA is a carbonyl and sulfhydryl reactive heterobifunctional crosslinking reagent[1]. Uses: Scientific research. Category: Biochemical assay reagents. Alternative Names: N-ε-Maleimidocaproic acid hydrazide TFA. CAS No. 151038-94-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-77961. | |
| 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: EMCS. CAS No. 55750-63-5. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 100 g. Product ID: HY-78961. | |
| 6-Mercaptopurine | 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mercaptopurine; 6-MP. CAS No. 50-44-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-13677. | |
| 6-Methoxy-2-[2-(3-methoxyphenyl)ethyl]chromone | 6-Methoxy-2-[2-(3-methoxyphenyl)ethyl]chromone (compound 12) is a chromenone[1]. Uses: Scientific research. Category: Natural products. CAS No. 84294-88-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12284. | |
| 6-Methoxy-2-(2-phenylethyl)chromone | 6-Methoxy-2-(2-phenylethyl)chromone (compound 9) is a 2-(2-phenylethyl)chromone (ΒΌ2-(2-phenylethyl)-4H-1-benzopyran-4- one) derivative[1]. Uses: Scientific research. Category: Natural products. CAS No. 84294-89-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12285. | |
| 6-Methoxydihydrosanguinarine | 6-Methoxydihydrosanguinarine is an alkaloid with activity across multiple cancer cell types. 6-Methoxydihydrosanguinarine activates IRE1/JNK signaling, blocks Akt/mTOR and PI3K/AKT/mTOR pathways, reduces expression of Cdc25C, CyclinB1, Cdc2, YAP/TAZ, Survivin, GPX4, and EGFR, upregulates IRE1 and DR5, and activates JNK and caspases. 6-Methoxydihydrosanguinarine induces apoptosis, G2/M phase arrest, DNA damage, ROS generation, lipid peroxidation, ferroptosis, autophagy, and suppresses cancer cell growth. 6-Methoxydihydrosanguinarine disruptes the biofilm formation of Candida albicans (C. albicans). 6-Methoxydihydrosanguinarine can be used for the research of non-small cell lung cancer, hepatocellular carcinoma, melanoma, colon carcinoma, ovarian cancer and breast cancer[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72401-54-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N3000. | |
| 6-Methyl-DL-tryptophan | 6-Methyl-DL-tryptophan is a kind of biochemical reagent. Uses: Scientific research. Category: Signaling pathways. CAS No. 2280-85-5. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W142072. | |
| 6-OAU | 6-OAU (GTPL5846) (6-n-octylaminouracil) is an GPR84 (G protein-coupled receptor 84) agonist, with an EC50 value of 105 nM. 6-OAU works as a chemoattractant to both PMNs and macrophages, and amplifies the proinflammatory cytokine IL-8, shows proinflammatory function. 6-OAU also displays anti-bacterial function[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GTPL5846. CAS No. 83797-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12764. | |
| 6-O-Methyldeoxyguanosine | O6-Methyldeoxy guanosine; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: O6-Methyl-2-deoxyguanosine. CAS No. 964-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W347492. | |
| 6-O-Methyl Guanosine | 6-O-Methyl Guanosine is a Ribonucleoside. Replacement of the conserved G5, G8 or G12 residues in hammerhead ribozymes with 6-O-Methyl Guanosine reduces kcat without altering Km. 6-O-Methyl Guanosine exerts position-dependent regulatory effects on ribosomal velocity and fidelity. When 6-O-Methyl Guanosine is located at the first or third position of a codon, it decreases the accuracy of tRNA selection. When 6-O-Methyl Guanosine is located at the second position of a codon, it slows down the peptide bond formation rate of cognate aminoacyl-tRNA but does not change the reaction rate of near-cognate aminoacyl-tRNA[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7803-88-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111648. | |
| 6-O-Propynyl-2'-deoxyguanosine | 6-O-Propynyl-2'-deoxyguanosine is a click chemistry reagent containing an alkyne group. 6-O-Propynyl-2'-deoxyguanosine can be used for the research of various biochemical[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1640051-47-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151688. | |
| 6-Oxolithocholic acid | 6-Oxolithocholic acid is a bile acid metabolite derived from Lithocholic acid (HY-B0172). 6-Oxolithocholic acid has high cytotoxicity and can induce apoptosis, especially in hepatocytes. 6-Oxolithocholic acid can participate in the regulation of bile acid metabolism and synthesis and affect the metabolic pathway of cholesterol. 6-Oxolithocholic acid can be used to study the role of bile acids in health and disease, especially in the context of digestive and liver diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Ketolithocholic acid. CAS No. 2393-61-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W587530. | |
| 6PGD-IN-1 | 6PGD-IN-1 (compound S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD). IC50 and Kd the value of 17.8μM and 17.1 μM respectively. 6PGD-IN-1 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Hydroxy-8-methoxyanthraquinone. CAS No. 5539-66-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N7850. | |
| 6-Phosphogluconic acid trisodium | 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 53411-70-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W011184. | |
| 6PPD | 6PPD is a rubber antioxidant that scavenges ozone and forms nitro radicals. Exposure to 6PPD reduces the hatching rate, impairs spontaneous locomotor activity, shortens body length and causes malformations in zebrafish embryos. 6PPD also induces oxidative stress in zebrafish embryos[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 793-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1 k g. Product ID: HY-W011689. | |
| 6PPD-Q | 6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation.6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6PPD-Quinone. CAS No. 2754428-18-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153169. | |
| 6PPD-quinone-d5 | 6PPD-quinone-d5 is the deuterium labeled 6PPD-quinone[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750119-14-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-152039S. | |
| 6RK73 | 6RK73 is a covalent irreversible and specific UCHL1 inhibitor with an IC50 of 0.23 μM. 6RK73 shows almost no inhibition of UCHL3 (IC50=236 μM). 6RK73 specifically inhibit UCHL1 activity in breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1895050-66-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-133118. | |
| (6S)-CP-470711 | (6S)-CP-470711 (Compound 8) is an inhibitor for sorbitol dehydrogenase, that inhibits human and rat SDH with IC50 of 19 nM and 27 nM. (6S)-CP-470711 ameliorates the Streptozotocin (HY-13753)-induced diabetes in rats models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 300552-09-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-164605. | |
| 6'-Sialyllactose | 6'-Sialyllactose promotes the growth of beneficial bacteria (such as Bifidobacterium and lactobacillus) and inhibits the proliferation of harmful bacteria. 6'-Sialyllactose exhibits anti-inflammatory and anti-angiogenic activities. 6'-Sialyllactose promotes the muscle health[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 35890-39-2. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-N10521. | |
| 6'-Sialyllactose sodium | 6'-Sialyllactose sodium promotes the growth of beneficial bacteria (such as Bifidobacterium and lactobacillus) and inhibits the proliferation of harmful bacteria. 6'-Sialyllactose sodium exhibits anti-inflammatory and anti-angiogenic activities. 6'-Sialyllactose sodium promotes the muscle health[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 157574-76-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137335. | |
| 6SLN | 6SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Neu5Acα2-6Galβ1-4GlcNAc. CAS No. 64364-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164390. | |
| 6-TAMRA-SE | 6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester. CAS No. 150810-69-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D0049. | |
| 6-Thio-2'-Deoxyguanosine | 6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-thio-dG; β-TGdR. CAS No. 789-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18762. | |
| 6-Thioguanine | 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thioguanine; 2-Amino-6-purinethiol. CAS No. 154-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-13765. | |
| 6-Thioguanosine | 6-Thioguanosine (6-Mercaptoguanosine), an active nucleoside, is an Azathioprine metabolite. 6-Thioguanosine has immunosuppressive effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Mercaptoguanosine. CAS No. 85-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-119499. | |
| 6-?Thioinosine | 6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6TI; 6-Mercaptopurine riboside. CAS No. 574-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128671. | |
| 7,12-Diketolithocholic acid | 7,12-Diketolithocholic acid (7,12-Diketo-LCA) is a bile acid, which can be produced in the host-gut microbial co-metabolism of the bile acid pool[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7,12-Dioxolithocholic acid; 3-Hydroxy-7,12-diketocholanoic acid; 7,12-Diketo-LCA. CAS No. 517-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-41325. | |
| 7,3',4'-Trihydroxyisoflavone | 7,3',4'-Trihydroxyisoflavone, a major metabolite of Daidzein, is an ATP-competitive inhibitor of Cot (Tpl2/MAP3K8) and MKK4. 7,3',4'-Trihydroxyisoflavone has anticancer, anti-angiogenic, chemoprotective, and free radical scavenging activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 485-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124953. | |
| 740 Y-P | 740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 740YPDGFR; PDGFR 740Y-P. CAS No. 1236188-16-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0175. | |
| 7,4'-Di-O-methylapigenin | 7,4'-Di-O-methylapigenin (4',7-Dimethoxy-5-Hydroxyflavone) is a flavonoid present in Lethedon tannaensis. 7,4'-Di-O-methylapigenin exhibits cytotoxicity against human nasopharyngeal carcinoma cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4',7-Dimethoxy-5-Hydroxyflavone. CAS No. 5128-44-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2144. | |
| 7,8-Dihydro-L-biopterin | 7,8-Dihydro-L-biopterin is a NOS uncoupling inducer with blood-brain barrier permeability, and it is a reduced non-conjugated pteridine. 7,8-Dihydro-L-biopterin is the main metabolite of 4-amino-tetrahydro-L-biopterin, and it undergoes photooxidation to form biopterin. 7,8-Dihydro-L-biopterin promotes the conversion of nitric oxide synthase to a superoxide-producing form, thereby increasing oxidative stress levels in the renal outer medulla and inducing apoptosis. 7,8-Dihydro-L-biopterin is sensitive to the inhibitory effect of SOD, and it can be applied to research related to salt-sensitive hypertension, moderate to severe traumatic brain injury, and neurodegenerative diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6779-87-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008646. | |
| 7,8-Dihydroneopterin | 7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1218-98-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-136341. | |
| 7,8-Dihydroxyflavone | 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38183-03-8. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W013372. | |
| 7ACC2 | 7ACC2 is a potent monocarboxylate transporter (MCT) inhibitor with an IC50 of 11 nM for inhibition of [14C]-lactate influx. 7ACC2 is also a potent inhibitor of mitochondrial pyruvate transport. 7ACC2 is an anticancer agent through inhibition of lactate flux[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1472624-85-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0713. | |
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