MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| 5-HMSiR-Hoechst | 5-HMSiR-Hoechst is a DNA probe. 5-HMSiR-Hoechst comprises Hoechst 33258 and spontaneously blinking far-red hydroxymethyl silicon-rhodamine (HMSiR). 5-HMSiR-Hoechst can stain living cells. Ex/Em=640 nm/675 nm[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2996108-30-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D2222. |  |
| 5-HT1A modulator 2 hydrochloride | 5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT (HY-112061), is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3880-76-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-136621. | |
| 5-Hydroxy-2'-deoxyuridine | 5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-OHdU. CAS No. 5168-36-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130801. | |
| 5-Hydroxycytidine | 5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39638-73-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z15868. | |
| 5-Hydroxydecanoate sodium | 5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71186-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136615. | |
| 5-Hydroxyindole-3-acetic acid | 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. Uses: Scientific research. Category: Signaling pathways. CAS No. 54-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-W008253. | |
| 5-Hydroxyindole-3-acetic acid-d2 | 5-Hydroxyindole-3-acetic acid-d2 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. Uses: Scientific research. Category: Signaling pathways. CAS No. 56209-31-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W008253S. | |
| 5-Hydroxyindole-3-acetic acid (Standard) | 5-Hydroxyindole-3-acetic acid (Standard) is the analytical standard of 5-Hydroxyindole-3-acetic acid. This product is intended for research and analytical applications. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. Uses: Scientific research. Category: Signaling pathways. CAS No. 54-16-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008253R. | |
| 5-Hydroxylansoprazole | 5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is metabolized by CYP2C19 forming 5-Hydroxylansoprazole. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatment of various peptic diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG1908. CAS No. 131926-98-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118283. | |
| 5-Hydroxymethyl-2'-deoxycytidine-d3 | 5-Hydroxymethyl-2'-deoxycytidine-d3 (5hmdC-d3) is the deuterium labeled 5-Hydroxymethyl-2'-deoxycytidine (HY-131394). 5-Hydroxymethyl-2-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2-deoxycytidine may serve as a marker of irreversibly damaged cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5hmdC-d3. CAS No. 1585142-60-4. Pack Sizes: 1 mg. Product ID: HY-W654228. | |
| 5-Hydroxymethyl-2'-deoxyuridine | 5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5116-24-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-129983. | |
| 5-(Hydroxymethyl)cytidine | 5-(Hydroxymethyl)cytidine is a purine nucleoside analog that can be used in oligonucleotide synthesis. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19235-17-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-152854. | |
| 5-Hydroxymethylcytosine | 5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development. 5-Hydroxymethylcytosine can be used for the study of non-small cell lung cancer (NSCLC), neurodegenerative diseases (Alzheimers, Parkinsons) and hematological malignancies (acute myeloid leukemia, myelodysplastic syndromes)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5hmC. CAS No. 1123-95-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W018324. | |
| 5-Hydroxymethylfurfural | 5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Hydroxymethyl-5-furfural; 2-Formyl-5-hydroxymethylfuran. CAS No. 67-47-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g; 1000 g. Product ID: HY-Y0051. | |
| 5-Hydroxymethylfurfural-13C6 | 5-Hydroxymethylfurfural-13C6 (2-Hydroxymethyl-5-furfural-13C6; 2-Formyl-5-hydroxymethylfuran-13C6) is a 13C labeled 5-Hydroxymethylfurfural (HY-Y0051). 5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Hydroxymethyl-5-furfural-13C6; 2-Formyl-5-hydroxymethylfuran-13C6. CAS No. 1219193-98-2. Pack Sizes: 1 mg. Product ID: HY-Y0051S. | |
| 5-Hydroxymethyl uridine | 5-Hydroxymethyl uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 30414-00-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-W394106. | |
| 5-Hydroxyomeprazole | 5-Hydroxyomeprazole (Hydroxyomeprazole) is a major metabolite of Omeprazole (HY-B0113) through catalysis by CYP2C19[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroxyomeprazole. CAS No. 92340-57-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-126857. | |
| 5-Hydroxy Omeprazole-d3 | 5-Hydroxy Omeprazole-d3 is deuterium labeled 5-Hydroxyomeprazole. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748479-83-4. Pack Sizes: 1 mg. Product ID: HY-126857S. | |
| 5-Hydroxytryptophan | 5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. [1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 5-HTP; DL-5-Hydroxytryptophan. CAS No. 56-69-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0122. | |
| 5-Hydroxytryptophol | 5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154-02-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W041019. | |
| 5-Hydroxyuridine | 5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OHUrd. CAS No. 957-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-130805. | |
| 5-IAF | 5-IAF (5-Iodoacetamidofluorescein) is an idoacetamide derivate of fluoresceine. 5-IAF can be used as fluorescent probe that labels proteins and other molecules having free thiols (cysteine side chains)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Iodoacetamidofluorescein. CAS No. 63368-54-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0807. | |
| 5-Iodo-cytidine | 5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Iodo-D-cytidine. CAS No. 1147-23-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W008615. | |
| 5-Iodotubercidin | 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 113939; 5-ITu. CAS No. 24386-93-4. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15424. | |
| 5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite | 5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides. Uses: Scientific research. Category: Signaling pathways. CAS No. 166593-57-3. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-W336559. | |
| 5-Methoxycarbonylmethyl-2-thiouridine | 5-Methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20299-15-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-152710. | |
| 5-Methoxycarbonyl methyl uridine | Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 29428-50-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152858. | |
| 5'-Methoxynobiletin | 5'-Methoxynobiletin is a potent and orally active antinociceptive and anti-inflammatory agent. 5'-Methoxynobiletin is a polymethoxyflavone, that can be isolated from A. conyzoides[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6965-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134602. | |
| 5-Methoxytryptamine | 5-Methoxytryptamine, a metabolite of Melatonin, is a nonselective 5-HT receptor agonist. 5-Methoxytryptamine has no affinity for the 5-HT3 receptor. 5-Methoxytryptamine is also a potent antioxidant and has radioprotective action[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: O-Methylserotonin. CAS No. 608-07-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g. Product ID: HY-W015169. | |
| 5-Methylcytidine | 5-Methylcytidine is a nucleoside compound. 5-Methylcytidine has antiviral activity, and its IC50 against HSV-1 is 0.06 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140-61-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg. Product ID: HY-113135. | |
| 5-Methylcytidine (Standard) | 5-Methylcytidine (Standard) is the analytical standard of 5-Methylcytidine. This product is intended for research and analytical applications. 5-Methylcytidine is a nucleoside compound. 5-Methylcytidine has antiviral activity, and its IC50 against HSV-1 is 0.06 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140-61-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113135R. | |
| 5-Methylcytosine-d4 | 5-Methylcytosine-d4 is the deuterium labeled 5-Methylcytosine (HY-W008091). 5-Methylcytosine is a well-characterized DNA modification in prokaryotes and eukaryotes. 5-Methylcytosine forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and affects mRNA translation. 5-Methylcytosine can be oxidized to generate 5hmC, 5fC, and 5caC. 5-Methylcytosine can be used in epigenetics, developmental biology, and the study of diseases such as colorectal cancer and hepatocellular carcinoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219795-15-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W008091S. | |
| 5-Methyltetrahydrofolic acid | 5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Methyl THF; 5-MTHF. CAS No. 134-35-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-113046. | |
| 5-Methyltetrahydrofolic acid-d3 | 5-(Methyl-d3)tetrahydrofolic Acid is the deuterium labeled 5-(Methyl)tetrahydrofolic Acid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Methyl THF-d3; 5-MTHF-d3. CAS No. 1356019-97-0. Pack Sizes: 500 μg. Product ID: HY-132384S. | |
| 5-Methyltetrahydrofolic acid (Standard) | Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Methyl THF (Standard); 5-MTHF (Standard). CAS No. 134-35-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113046R. | |
| 5'-Methylthioadenosine | 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5'-(Methylthio)-5'-deoxyadenosine; 5'-Deoxy-5'-(methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine. CAS No. 2457-80-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-16938. | |
| 5'-Methylthioadenosine-d3 | 5'-Methylthioadenosine-d3 is the deuterium labeled 5'-Methylthioadenosine[1]. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5'-(Methylthio)-5'-deoxyadenosine-d3; 5'-Deoxy-5'-(methylthio)adenosine-d3; 5'-S-Methyl-5'-thioadenosine-d3. CAS No. 174838-38-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-16938S1. | |
| 5-Methyluridine | 5-Methyluridine (m5U) is an RNA modified nucleotide generated by RNA methyltransferases (such as TrmA and RumA), which mainly targets specific uracil sites in RNA molecules such as the T arm of tRNA and rRNA. 5-Methyluridine relies on enzyme recognition of RNA secondary/tertiary structures (such as the T loop of tRNA or the specific stem-loop structure of rRNA) and participates in physiological processes such as translation accuracy and ribosome function by stabilizing RNA folding or regulating base pairing[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1463-10-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-W009444. | |
| 5MPN | 5MPN is a first-in-class, potent, orally active and selective 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) inhibitor. 5MPN appears to be a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN does not inhibit PFK-1 or PFKFB3. 5MPN targets the sugar metabolism of tumors and suppresses proliferation of multiple human cancer cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 47208-82-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123981. | |
| 5'-N-Ethylcarboxamidoadenosine | 5'-N-Ethylcarboxamidoadenosine (NECA) is a nonselective adenosine receptor agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NECA. CAS No. 35920-39-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-103173. | |
| 5-n-Heneicosylresorcinol | 5-n-Heneicosylresorcinol (5-Heneicosylresorcinol) is an active n-alkyl(enyl)resorcinols (AR) occurring in cereal products from Colombia. Antifungal activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Heneicosylresorcinol. CAS No. 70110-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-113430. | |
| 5-(N,N-Hexamethylene)-amiloride | 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hexamethylene amiloride; HMA. CAS No. 1428-95-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128067. | |
| 5-O-(4,4-Dimethoxytrityl)-2-O-methyluridine | 5-O-(4,4-Dimethoxytrityl)-2-O-methyluridine is a 2'-O-methyluridine derivative bearing a 5'-O-(4,4'-dimethoxytrityl) protecting group.5-O-(4,4-Dimethoxytrityl)-2-O-methyluridine serves as a starting material for synthesis of a conformationally rigid cyclic uridylic acid derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103285-22-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-W025438. | |
| 5-O-Demethylnobiletin | 5-O-Demethylnobiletin (5-Demethylnobiletin), a polymethoxyflavone isolated from Citrus jambhiri Lush., is a direct inhibition of 5-LOX (IC50=0.1 μM), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Demethylnobiletin. CAS No. 2174-59-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N1942. | |
| 5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite) | 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite blongs to modified antisense oligonucleotide. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite allows the formation of a specific conformation of the furanose ring of the oligonucleotide through the introduction of a cEt modification, enhancing the ability to hybridize to complementary RNA. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is mainly used in the research of regulation of gene expression related to metabolic diseases, cardiovascular diseases, cancers and the development of antisense compounds[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1197033-17-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-148505. | |
| 5-O-(E)-p-Coumaroylquinic acid | 5-O-(E)-p-Coumaroylquinic acid, a quinic acid derivative, is a potent phytochemical agent against hepatitis B virus[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5746-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N10543. | |
| 5-O-Methylembelin | 5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9, inducible degrader of the low-density lipoprotein receptor (IDLR), and sterol regulatory element binding protein 2 (SREBP2) mRNA expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56005-10-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W510159. | |
| 5-Pentadecylresorcinol | 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adipostatin A. CAS No. 3158-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116934. | |
| 5-Ph-IAA | 5-Ph-IAA is a derivative of IAA. 5-Ph-IAA, a ligand, establishes the auxin-inducible degron 2 (AID2) system together with an OsTIR1 (F74G) mutant. AID2 induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, causing tumor suppression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 168649-23-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134653. | |
| 5-Ph-IAA-AM | 5-Ph-IAA-AM is an eggshell-permeable 5-Ph-IAA (HY-134653) analog which contains an acetoxymethyl (AM) group. 5-Ph-IAA-AM affords an enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to disclosure the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2990123-10-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141894. | |
| 5'-Phosphoguanylyl-(3',5')-guanosine | 5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: pGpG. CAS No. 33008-99-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137662. | |
| 5-Propargylamino-dCTP | 5-Propargylamino-dCTP is a sustrate for DNA polymerases. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 115899-39-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-132142. | |
| 5-PT formic | 5-PT (5-Propargyltryptamide) formic is an alkyne-functionalized 5-HT (HY-B1473A) derivative and serotonylation substrate, taken up by living cells. 5-PT formic conjugated to a biotin enables identification of serotonylated proteins via copper-click chemistry and mass spectrometry. 5-PT formic labels and isolates serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT formic can be used for the research of bronchopulmonary dysplasia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Propargyltryptamide formic. CAS No. 2906227-87-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156562A. | |
| 5-TAMRA | 5-TAMRA can produce bright, pH-insensitive orange-red fluorescence (excitation and emission extremes of 546/579) and has good photostability. 5-TAMRA is mainly used as a fluorescent marker for the synthesis and study of specific oligonucleotide probes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 91809-66-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15942. | |
| 5-TAMRA-SE | 5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability (Ex/Em = 565/580 nm). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester. CAS No. 150810-68-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0048. | |
| 5-XDP sodium | 5-XDP sodium (Xanthosine 5' -diphosphate sodium) is an ADP analog involved in the synthesis of ribosomes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Xanthosine 5-diphosphate sodium. CAS No. 105931-37-1. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-158359. | |
| 5Z-7-Oxozeaenol | 5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FR148083; L783279; LL-Z 1640-2. CAS No. 253863-19-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-12686. | |
| 666-15 | 666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM. 666-15 suppresses tumor growth in a breast cancer xenograft model[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1433286-70-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101120. | |
| 6,7-Dichloroquinoline-5,8-dione | 6,7-Dichloroquinoline-5,8-dione (compound DA3002) is a potent CDC25B2 inhibitor with an IC50 value of 4.6 μM. 6,7-Dichloroquinoline-5,8-dione has the potential for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6541-19-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W102931. | |
| 6',7'-Dihydroxybergamottin | 6',7'-Dihydroxybergamottin (6,7-DHB), a furanocoumarin, is a potent CYP3A4 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6,7-DHB. CAS No. 145414-76-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8354. | |
| 6,7-Dimethoxy-2-(2-phenylethyl)chromone | 6,7-Dimethoxy-2-(2-phenylethyl)chromone is a natural compound[1]. Uses: Scientific research. Category: Natural products. CAS No. 84294-87-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8123. | |
| 680C91 | 680C91 is an orally active, selective tryptophan 2,3-dioxygenase (TDO) inhibitor with a Ki of 51 nM. TDO is the key enzyme of tryptophan catabolism. 680C91 can be used for the research of cancer immunotherapy and Alzheimers Disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 163239-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108681. | |
| 6-AF488 tyramide | 6-AF488 tyramide is a bright, green fluorescent dye (Ex=496 nm, Em=524 nm). 6-AF488 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2435665-39-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D2874. | |
| 6-Alkynyl fucose | 6-Alkynyl fucose is a tool in the study of protein O-fucosylation[1]. 6-Alkynyl fucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 935658-91-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115495. | |
| 6α-Hydroxy paclitaxel | 6α-Hydroxy paclitaxel is one of the main metabolites of Paclitaxel (PTX) (HY-B0015), and it is generated by the liver cytochrome P450 enzyme CYP2C8. 6α-Hydroxy paclitaxel has bone marrow toxicity, but it can enhance the cytotoxicity of PTX against leukemia cells without causing cell toxicity. 6α-Hydroxy paclitaxel can be used in leukemia research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 153212-75-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-125348. | |
| 6-Amino-1-hexanethiol hydrochloride | 6-Amino-1-hexanethiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 31098-40-5. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-33462. | |
| 6-Amino-1-hexyne | 6-Amino-1-hexyne is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 15252-45-6. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W073472. | |
| 6-Amino-6-deoxy-β-cyclodextrin | 6-Amino-6-deoxy-β-cyclodextrin is a cyclodextrin derivative that can be used to prepare other cyclodextrin derivatives. 6-Amino-6-deoxy-β-cyclodextrin can also be used as a chiral selector for chiral separation of α-amino acid derivatives by capillary electrophoresis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 29390-67-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W129394. | |
| 6-Aminocaproic acid-d6 | 6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EACA-d6; Epsilon-Amino-n-caproic acid-d6; 6-Aminohexanoic acid-d6. CAS No. 1228656-08-3. Pack Sizes: 1 mg. Product ID: HY-B0236S. | |
| 6-Amino-D-luciferin | 6-Amino-D-luciferin is a derivative of D-luciferin (HY-12591A) with an amino group replacing the 6-hydroxyl group. 6-Amino-D-luciferin is a natural substrate of luciferase (Luc) and can be used for IVIS imaging in cell/animal experiments[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 161055-47-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-126994. | |
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