MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| 4-Methylumbelliferyl-α-D-galactopyranoside | 4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4MU-α-Gal. CAS No. 38597-12-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-118135. |  |
| 4-Methylumbelliferyl α-L-iduronide | 4-Methylumbelliferyl α-L-iduronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 66966-09-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-W127708. | |
| 4-Methylumbelliferyl β-D-cellobioside | 4-Methylumbelliferyl β-D-cellobioside is a substrate of Cellulase (HY-B2220). 4-Methylumbelliferyl β-D-cellobioside can be hydrolyzed and produces fluorescent 4-methylumbelliferone, which can be used to study the kinetics of cellulases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72626-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137333. | |
| 4-Methylumbelliferyl β-D-Glucopyranoside | 4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity[1]. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18997-57-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-123633. | |
| 4-Methylumbelliferyl-β-D-glucuronide hydrate | 4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MUG. CAS No. 881005-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-D0935A. | |
| 4-Methylumbelliferyl-β-D-xylopyranoside | 4-Methylumbelliferyl-β-D-xylopyranoside (4-Methylumbelliferyl-β-D-xyloside) is an enzymatically hydrolyzable β-D-xylopyranoside substrate. The enzymatic hydrolysis of 4-Methylumbelliferyl-β-D-xylopyranoside is mediated by the stereochemistry-retaining β-D-xylosidase GSXynB2 via a two-step catalytic process (xylosylation followed by dexylosidation). 4-Methylumbelliferyl-β-D-xylopyranoside serves as a substrate for the β-xylosidase of Trichoderma reesei QM 9414, and its enzymatic hydrolysis process is limited by the dexylosidation step. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Methylumbelliferyl-β-D-xyloside. CAS No. 6734-33-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-137824. | |
| 4-Methylumbelliferyl butyrate | 4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 17695-46-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-135036. | |
| 4-Methylumbelliferyl octanoate | 4-Methylumbelliferyl octanoate is a octoate. 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20671-66-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g. Product ID: HY-W099648. | |
| 4-Methylumbelliferyl phosphate | 4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-MUP; MUP. CAS No. 3368-4-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-D0994. | |
| 4-Methylumbelliferyl sulfate potassium | 4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples. Uses: Scientific research. Category: Signaling pathways. CAS No. 15220-11-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-137855. | |
| 4μ8C | 4μ8C (IRE1 Inhibitor III) is a small-molecule inhibitor of IRE1α. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IRE1 Inhibitor III. CAS No. 14003-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19707. | |
| 4-MU-α-GlcNS sodium | 4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH2. 4-MU-α-GlcNH2 can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 460085-45-4. Pack Sizes: 500 μg. Product ID: HY-D1632. | |
| 4-MUNANA | 4-MUNANA is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76204-02-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W019823. | |
| 4-N3Pfp-NHS ester | 4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 126695-58-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-126525. | |
| (4-NH2)-Exatecan | (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZ14170132. CAS No. 2495742-21-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145397. | |
| 4-Nitrobenzyl alcohol (4-Nitrobenzenemathanol) | 4-Nitrobenzyl alcohol (4-Nitrobenzenemathanol) is a nitro compound used as a reactant in drug synthesis. 4-Nitrobenzyl alcohol can be catalyzed to 4-nitrobenzaldehyde by the enzyme encoded by the benzyl alcohol dehydrogenase gene (ntnD)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Nitrobenzenemathanol; 4-Nitrobenzyl alcohol. CAS No. 619-73-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g. Product ID: HY-W015570. | |
| 4-Nitrocatechol sulfate dipotassium salt | 4-Nitrocatechol sulfate potassium salt (Dipotassium nitrocatechol sulfate) is an aromatic sulfate that can serve as a chromogenic substrate for sulfatase. 4-Nitrocatechol sulfate potassium salt can be used to determine the activities of glycosaminoglycan (GAG) degrading enzymes aryl sulfatase B and exonucleosidase[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dipotassium nitrocatechol sulfate. CAS No. 14528-64-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-D1213. | |
| 4-Nitrophenyl a-D-glucopyranoside | 4-Nitrophenyl a-D-glucopyranoside is a chromogenic substrate for α-glucosidase. 4-Nitrophenyl a-D-glucopyranoside can be used to measure of α-glucosidase activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3767-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-W011411. | |
| 4-Nitrophenyl β-D-Cellobioside | 4-Nitrophenyl β-D-Cellobioside (p-Nitrophenyl β-D-cellobioside) is a cellotriose analog. 4-Nitrophenyl β-D-Cellobioside is hydrolyzed by β-glucosidases such as TxGH116 and ThCel7B. 4-Nitrophenyl β-D-Cellobioside can also be hydrolyzed by exoglucanases and endoglucanases to produce p-nitrophenol (PNP). 4-Nitrophenyl β-D-Cellobioside can be used to detect cellulase activity[1][2][31][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Nitrophenyl β-D-Cellobioside. CAS No. 3482-57-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-137827. | |
| 4-Nitrophenyl β-D-glucopyranoside | 4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2492-87-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-15927. | |
| 4-Nitrophenyl β-D-glucuronide | 4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-Nitrophenol. 4-Nitrophenyl β-D-glucuronide is the chromogenic substrate for β-glucuronidase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: pNPG_1. CAS No. 10344-94-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-W039892. | |
| 4-Nitrophenylboronic acid | 4-Nitrophenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 24067-17-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-50807. | |
| 4-Nitrophenyl butyrate | 4-Nitrophenyl butyrate consists of butyric acid chains esterified with 4-nitrophenol groups, thus giving it a yellow color. This compound is commonly used as a substrate in enzyme assays to measure esterase and lipase activity. When these enzymes cleave the ester bond, the nitrophenol group is released and the color changes from yellow to orange. Thus, the rate of color change can be used to determine enzyme activity. In addition, 4-Nitrophenyl butyrate can also be used as organic synthesis reagent and dye intermediate. Uses: Scientific research. Category: Signaling pathways. CAS No. 2635-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W014449. | |
| 4-Nitrophenyl-N-acetyl-β-D-glucosaminide | 4-Nitrophenyl-N-acetyl-β-D-glucosaminide, an artificial substrate of N-acetyl-beta-D-hexosaminidase (NAGase), can be used in rapid and accurate rate assay for N-acetyl-beta-D-hexosaminidase. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide is highly soluble and stable. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide can be used for the study of renal tubular injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3459-18-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-W011183. | |
| 4-Nitrophenyl palmitate | 4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate) is a chromogenic substrate for lipases and esterases. Upon enzymatic hydrolysis, 4-Nitrophenyl palmitate releases p-nitrophenol, which can be quantified by colorimetric detection at 410 nm as a measure of enzymatic activity. 4-Nitrophenyl palmitate is used to characterize the activity of various bacterial and mammalian enzymes, including those from Burkholderia and porcine pancreatic lipase[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate; pNpp. CAS No. 1492-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W013168. | |
| 4-Nitrophenyl phosphate | 4-Nitrophenyl phosphate (p-Nitrophenyl phosphate) is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases.4-Nitrophenyl phosphate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Nitrophenyl phosphate. CAS No. 330-13-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116022. | |
| 4-Nitrophenyl phosphate disodium | 4-Nitrophenyl phosphate (p-Nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Nitrophenyl phosphate disodium. CAS No. 4264-83-9. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-15928. | |
| 4-Nitrophenyl phosphate disodium hexahydrate | 4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Nitrophenyl phosphate disodium hexahydrate. CAS No. 333338-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-116022A. | |
| 4-Nitrophthalonitrile | 4-Nitrophthalonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 31643-49-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-W018645. | |
| 4-Octyl itaconate | 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-OI. CAS No. 3133-16-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 250 mg; 500 mg; 1 g. Product ID: HY-112675. | |
| 4-OHE | 4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by omega-3 lipid peroxidation. 4-OHE reacts with deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine to form covalent adducts. 4-OHE induces apoptosis and exhibits genotoxicity. 4-OHE inhibits the growth of Gram-positive and Gram-negative bacteria, which correlates with its electrophilic reactivity towards nucleophilic biomolecules. 4-OHE is a chemical defense component of Dolycoris baccarum (sloe bug), and acts as a deterrent and toxin against insect predators[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-4-Oxo-2-hexenal. CAS No. 2492-43-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N12851. | |
| 4'-O-Methylpyridoxine | 4'-O-Methylpyridoxine is an orally active antivitamin B6 compound found in Ginkgo biloba seeds and leaves. 4'-O-Methylpyridoxine inhibits pyridoxal kinase. 4'-O-Methylpyridoxine reduces brain pyridoxal-5'-phosphate (PLP) levels, decreases gamma-aminobutyric acid/glutamate (GABA/Glu) ratio. 4'-O-Methylpyridoxine increases plasma levels of pyridoxal-5'-phosphate and pyridoxal. 4'-O-Methylpyridoxine induces hyperactivity, convulsions, pathological tissue changes, organ damage in rodent brain and heart[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 1464-33-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N8157. | |
| 4-Oxoretinoic acid-d3 | 4-Oxoretinoic acid-d3 is the deuterium labeled 4-Oxoretinoic acid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Keto retinoic acid-d3. CAS No. 1346606-26-5. Pack Sizes: 1 mg. Product ID: HY-107494S2. | |
| 4-Phenylbutyric acid | 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-PBA; Benzenebutyric acid. CAS No. 1821-12-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0281. | |
| 4-Phytase | 4-Phytase is a phosphohydrolase of inositol hexaphosphate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-89-2. Pack Sizes: 1 g; 5 g. Product ID: HY-P2808. | |
| 4-(Prop-2-yn-1-yloxy)piperidine hydrochloride | 4-(Prop-2-yn-1-yloxy)piperidine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1185100-09-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W170184. | |
| (4S)-GLP-1 receptor agonist 14 | (4S)-GLP-1 receptor agonist 14 is a potent and orally active GLP-1 receptor agonist with an EC50 ≤ 20 nM. (4S)-GLP-1 receptor agonist 14 can be used for research on diabetes, obesity, metabolic diseases, cardiovascular diseases, liver diseases, nonalcoholic steatohepatitis (NASH), and other diseases associated with GLP-1 receptor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758659-09-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-164774. | |
| 4-tert-Butylacetophenone | 4-tert-Butylacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 943-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0621. | |
| 4-Thiothymidine | 4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7236-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W587829. | |
| 4-Thiouridine | 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13957-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011793. | |
| 4-Thiouridine 5-triphosphate tetralithium | 4-Thiouridine 5-triphosphate (4-Thio-UTP) tetrasodium (Compound 15) is a UTP analog and potent P2Y2 and P2Y4 agonist with EC50 values of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5-triphosphate tetrasodium can be used in cross-linking experiments and transcriptional complex labeling studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Thio-UTP tetralithium. CAS No. 20188-72-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-154840. | |
| 4-[(Trans-4-aminocyclohexyl)oxy]-2-chloro-Benzonitrile hydrochloride | 4-[(Trans-4-aminocyclohexyl)oxy]-2-chloro-Benzonitrile hydrochloride is a drug intermediate for synthesis of various active compounds. Uses: Scientific research. Category: Signaling pathways. CAS No. 1335049-54-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W145437. | |
| 4-(Trifluoromethoxy)benzoic acid-d4 | 4-(Trifluoromethoxy)benzoic acid-d4 is the deuterium labeled 4-(Trifluoromethoxy)benzoic acid[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2741881-05-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W014633S. | |
| 4-(Trifluoromethyl)-L-phenylalanine | 4-(Trifluoromethyl)-L-phenylalanine is a phenylalanine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114926-38-4. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W013962. | |
| 4-Vinylcyclohexene dioxide | 4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vinylcyclohexene diepoxide. CAS No. 106-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-106591A. | |
| 5,15-Diphenyl-10,20-di(pyridin-4-yl)porphyrin | 5,15-Diphenyl-10,20-di(pyridin-4-yl)porphyrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,15-Di(4-Pyridyl)-10,20-diphenylporphyrin. CAS No. 71410-72-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W075433. | |
| 5,15-Diphenylporphyrin | 5,15-Diphenylporphyrin (5,15-DPP) is an inhibitor of the oncogenic transcription factor STAT3. 5,15-Diphenylporphyrin specifically binds to the SH2 domain of STAT3, blocking the pTyr-SH2 interaction, thereby inhibiting the dimerization, nuclear translocation and DNA binding activity of STAT3, and ultimately inhibiting the expression of cancer cell-related genes. 5,15-Diphenylporphyrin can be used in research fields related to the development of anticancer drugs | |
| 5,5',5''-((1,3,5-Triazine-2,4,6-triyl)tris(azanediyl))triisophthalic acid | 5,5',5''-((1,3,5-Triazine-2,4,6-triyl)tris(azanediyl))triisophthalic acid is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. CAS No. 776242-98-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W075445. | |
| 5,5,5-Trifluoro-DL-leucine | 5,5,5-Trifluoro-DL-leucine is a leucine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2792-72-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W037549. | |
| 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate | 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is a fluorescein-based reactive oxygen species (ROS) probe and also a MRP2 substrate. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate serves as a substrate for intracellular esterases, which cleave its acetate groups to generate a fluorescent product capable of detecting intracellular ROS. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is ATP-dependent and is transported via a single MRP2 binding site; it competes with LTC4 for MRP2 binding sites and inhibits MRP2-mediated LTC4 transport (Ex/Em = 496/525 nm)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 127770-45-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-D1078. | |
| 5(6)-Carboxyfluorescein | 5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers. CAS No. 72088-94-9. Pack Sizes: 500 mg; 1 g. Product ID: HY-15940. | |
| 5(6)-CFDA | 5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-(6)-Carboxyfluorescein diacetate; CFDA. CAS No. 124387-19-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-D0722. | |
| 5,6-Chrysenedione | 5,6-Chrysenedione is the photochemical degradation product of 6-Aminochrysene (HY-108315)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2051-10-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W718316. | |
| 5,6-Dichlorobenzimidazole riboside | 5,6-Dichlorobenzimidazole riboside (DRB) is a nucleoside analog that inhibits several carboxyl-terminal domain kinases, including casein kinase II and cell cycle-dependent kinases (CDK). 5, 6-dichlorobenzimidazole riboside has antitumor activity. 5, 6-dichlorobenzimidazole riboside can induce apoptosis[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DRB. CAS No. 53-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14392. | |
| 5,6-Dihydro-5-Fluorouracil | 5,6-Dihydro-5-Fluorouracil (5-DHFU; 5-Fluorodihydropyrimidine-2,4-dione) is the active metabolite of the thymidylate synthase inhibitor prodrug 5-fluorouracil (HY-90006), which is formed from 5-fluorouracil by dihydropyrimidine dehydrogenase (DPD). 5,6-Dihydro-5-Fluorouracil is cytotoxic to HaCaT keratinocytes (IC50=13.5 μM). Intravenous administration of 5,6-Dihydro-5-Fluorouracil (90 mg/kg/wk) in combination with 5-fluorouracil and the DPD inhibitor eniluracil (HY-10533) slows tumor growth in a rat colon cancer model. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-DHFU; 5-Fluorodihydropyrimidine-2,4-dione; 5-Fluorodihydrouracil. CAS No. 696-06-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-134160. | |
| 5,6-Dihydrouridine | 5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea. Uses: Scientific research. Category: Signaling pathways. CAS No. 5627-5-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113047. | |
| 5,6-Dihydroxyindole | 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3131-52-0. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-W018025. | |
| 5,6-Epoxyeicosatrienoic acid | 5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 (IC50=0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,6-EET; (±)5,6-EpETrE. CAS No. 87173-80-6. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-132184. | |
| 5(6)-FITC | 5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers. CAS No. 27072-45-3. Pack Sizes: 100 mg; 500 mg. Product ID: HY-15941. | |
| 5(6)-SFX ,SE | 5(6)-SFX ,SE (Compound SFX-SE) is a fluorescent dye for labeling primary amines and nascent proteins[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114616-31-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1109. | |
| 5(6)-TAMRA | 5(6)-TAMRA (5(6)-Carboxytetramethylrhodamine) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5(6)-Carboxytetramethylrhodamine. CAS No. 98181-63-6. Pack Sizes: 100 mg; 200 mg; 500 mg. Product ID: HY-15944. | |
| 5(6)-TAMRA SE | 5(6)-TAMRA SE is a fluorescent dye that emits red fluorescence. 5(6)-TAMRA SE binds to oligonucleotides and is used in DNA sequencing. 5(6)-TAMRA SE can be used in cancer research (Ex/Em = 565/580 nm)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester. CAS No. 246256-50-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0723. | |
| 5,6-trans-Vitamin D2 | 5,6-trans-Vitamin D2 is the isomer of Vitamin D2[1]. Uses: Scientific research. Category: Lipids. Alternative Names: 5,6-trans-Ergocalciferol; 5,6-trans-Calciferol; 5,6-trans-Ercalciol. CAS No. 51744-66-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76542A. | |
| 5,7-Dichlorokynurenic acid | 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid reduces NMDA-induced neuron injury. 5,7-Dichlorokynurenic acid increases social interaction time, increases open arm exploration time, disinhibits suppressed conflict responding in rodent models. 5,7-Dichlorokynurenic acid exhibits anxiolytic-like activity in rodent models and supports exploration of glycines role in NMDA receptor-mediated synaptic transmission[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,7-DCKA. CAS No. 131123-76-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100834. | |
| 5,7-Dimethoxyflavone | 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21392-57-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5011. | |
| 5A2-SC8 | 5A2-SC8 is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1857341-90-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145799. | |
| 5-AF594 tyramide | 5-AF594 tyramide is a red fluorescent dye (Ex=590 nm, Em=618 nm). 5-AF594 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-AF594 tyramide can be used for multiplex immunohistochemistry (mIHC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3046210-60-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D2872. | |
| 5α-Androstan-3β-ol | 5α-Androstan-3β-ol (Androstan), a saturated sterol, is a CAR (constitutive androstane receptor) inverse agonist ligand. 5α-Androstan-3β-ol (Androstan) increases the AmB-channel conductance in a concentration dependent manner[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3β-Hydroxy-5α-androstane. CAS No. 1224-92-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W013854. | |
| 5α-Cholestan-3β-ol-d5 | 5α-Cholestan-3β-ol-d5 is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dihydrocholesterol-d5; 5α-Cholestanol-d5; NSC 18188-d5. CAS No. 2260669-14-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107819S. | |
| 5'-Amino-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid | 5'-Amino-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. CAS No. 2230912-22-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W106292. | |
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