MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| OF-C4-Deg-Lin | OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2383003-60-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148855. |  |
| OF-Deg-Lin | OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs). Uses: Scientific research. Category: Signaling pathways. CAS No. 1853202-95-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-134782. | |
| Ofirnoflastum | Ofirnoflastum (Ofirnoflast) is an orally active first-in-class allosteric NEK7 inhibitor with an IC50 of 46 nM. Ofirnoflastum binds an allosteric site adjacent to NEK7s ATP-binding pocket, induces conformational shifts, disrupts NEK7-NLRP3 binding, blocks NLRP3 inflammasome assembly, spares NEK7s physiological functions, and suppresses caspase-1, caspase-8, NF-κB, and TNF activity. Ofirnoflastum reduces pro-inflammatory cytokine production, suppresses ASC specks, IL-1β release, pyroptotic cell death, and leukemic burden, induces apoptosis and erythroid differentiation, restores hematopoiesis, and improves outcomes in colitis models. Ofirnoflastum can be used for the research of myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ofirnoflast; HT-6184. CAS No. 2731294-23-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159520. | |
| Ofloxacin | Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. Ofloxacin shows inhibitory activity against vaccinia virus (VV). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hoe-280. CAS No. 82419-36-1. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0125. | |
| OG 488, acid | OG 488, acid, a fluorescent pH indicator, has many applications in biochemistry and neurosciences[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 195136-52-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1401. | |
| OG 488, SE | OG 488, SE (Oregon green 488 succinimidyl ester), a fluorescent pH indicator, has many applications in biochemistry and neurosciences[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oregon green 488 succinimidyl ester. CAS No. 198139-51-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133527. | |
| Ogerin | Ogerin, a chemical probe, is a selective GPR68 positive aliasing modulator (PAM) (pEC50=6.83) with a moderate antagonistic effect on A2A (Ki=220 nM). Ogerin inhibits the fear conditioning reflex in mice and also inhibits TGF-β-induced myofibroblast differentiation of fibroblasts from multiple organ systems. Ogerin can be used in the studies of fibrotic diseases and neurological disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1309198-71-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110279. | |
| OGG1-IN-08 | OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC50 value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 350997-39-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112902. | |
| OG-L002 | OG-L002 is a potent and highly selective LSD1 inhibitor with an IC50 of 0.02 μM. OG-L002 is a potent monoamine oxidases (MAO) inhibitor with IC50s of 1.38 μM and 0.72 μM for MAO-A and MAO-B, respectively. OG-L002 potently inhibits the expression of HSV IE genes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1357302-64-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19333. | |
| Oglufanide | Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-Glu-Trp-OH; L-Glutamyl-L-tryptophan. CAS No. 38101-59-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13718. | |
| Ogremorphin | Ogremorphin (OGM) is a G protein coupled sensor GPR68 inhibitor with anti-inflammatory and anti-tumor activities. Ogremorphin can inhibit the migration of human melanoma cells and induce ferroptosis in glioblastoma cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OGM; GPR68-IN-1; OGM-8345. CAS No. 352563-21-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154954. | |
| OGT 2115 | OGT 2115 is a potent, cell-permeable and orally active heparanase inhibitor with an IC50 of 0.4 μM. OGT 2115 has anti-angiogenic properties (IC50 of 1 μM). OGT 2115 also inhibits heparan sulfate degradation activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 853929-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100898. | |
| OGT-IN-4 | OGT-IN-4 (compound 4a) is an O-GlcNAc transferase (OGT) inhibitor with a Kd of 8 nM. OGT-IN-4 can be utilized in OGT related research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2411972-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125278. | |
| OICR-8268 | OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3000549-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149935. | |
| OICR-9429 | OICR-9429, a chemical probe, is high affinity WD repeat domain 5 (WDR5) inhibitor, competitively blocks WDR5 interaction with MLL protein via binding the central peptide-binding pocket of WDR5. OICR-9429 can suppress histone H3K4 trimethylation and can be used for the research of various cancers including non-MLL-rearranged leukaemia, colon, pancreatic, prostate cancer and bladder cancer (BCa) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1801787-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16993. | |
| Oil Red O | Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1320-06-5. Pack Sizes: 25 g. Product ID: HY-D1168. | |
| o-Iodobenzoic acid | o-Iodobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Iodobenzoic acid. CAS No. 88-67-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g. Product ID: HY-77433. | |
| OJT008 | OJT008 is an inhibitor of MtMetAP1c. OJT008 inhibits NiCl2- and CoCl2 activated MtMetAP1c with IC50s of 11 and 40 μM, respectively. OJT008 can used to study tuberculosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 256370-29-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157518. | |
| OK2 | OK2, a specific inhibitor of the CCN2/EGFR interaction, efficiently blocks CCN2/EGFR interaction through binding to the CT domain of CCN2. OK2 can be used for kidney fibrosis and chronic kidney disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2983020-14-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5314. | |
| Okadaic acid | Okadaic acid, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid induces tau phosphorylation[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 78111-17-8. Pack Sizes: 25 μg (124.2 μM * 250 μL in Ethanol). Product ID: HY-N6785. | |
| Okadaic acid sodium | Okadaic acid sodium, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid (sodium) has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid sodium increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid sodium induces tau phosphorylation[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 209266-80-8. Pack Sizes: 25 μg. Product ID: HY-N6785A. | |
| Okanin | Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 484-76-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6673. | |
| Olacaftor | Olacaftor (VX-440) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator extracted from patent US9782408. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-440. CAS No. 1897384-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112267. | |
| Olanexidine hydrochloride | Olanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 146509-94-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125654A. | |
| Olanzapine | Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY170053. CAS No. 132539-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14541. | |
| Olanzapine-d3 | Olanzapine-d3 (LY170053-d3) is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY170053-d3. CAS No. 786686-79-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14541S. | |
| Olanzapine thiolactam | Olanzapine thiolactam (compound 2) is an impurity of Olanzapine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1017241-36-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z4467. | |
| Olaparib | Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator. Olaparib cannot cross the intact blood-brain barrier (BBB)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD2281; KU0059436. CAS No. 763113-22-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-10162. | |
| Olaparib-d4-1 | Olaparib-d4-1 (AZD2281-d4-1) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD2281-d4-1; KU0059436-d4-1. CAS No. 2143107-55-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-10162S3. | |
| Olaparib (Standard) | Olaparib (Standard) is the analytical standard of Olaparib. This product is intended for research and analytical applications. Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD2281 (Standard); KU0059436 (Standard). CAS No. 763113-22-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10162R. | |
| Olaptesed pegol | Olaptesed pegol (NOX-A12) is a L-oligoribonucleotide aptamer targeting CXCL12 based on a pegylated structure. Olaptesed pegol neutralizes CXCL12, and CXCL12 inhibition mobilizes chronic lymphocytic leukemia cells into the circulation and prevents their homing into the protective microenvironment. Olaptesed pegol can enhances the infiltration of human primary T cells and NK cells and inhibit tumor growth companied with anti-PD-1 antibody. Olaptesed pegol can be used for researches of colon cancer and lymphocytic leukemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NOX-A12. CAS No. 1390628-22-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160041. | |
| Olaratumab | Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha (PDGFRα) human monoclonal IgG1 antibody with antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMC-3G3; LY3012207. CAS No. 1024603-93-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9922. | |
| Olcegepant | Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBN-4096; BIBN 4096BS. CAS No. 204697-65-4. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10095. | |
| Olcegepant hydrochloride | Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBN-4096 hydrochloride; BIBN4096BS hydrochloride. CAS No. 586368-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10095A. | |
| Oleacein | Oleacein (Compound 9) is an ACE inhibitor that can be isolated from J. grandiflorum. Oleacein is orally active and can be used in the study of metabolic and cardiovascular diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 149183-75-5. Pack Sizes: 1 mg. Product ID: HY-N8630. | |
| Oleamide | Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma. Uses: Scientific research. Category: Signaling pathways. CAS No. 301-02-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2327. | |
| Oleandrigenin | Oleandrigenin is a potent cardiotonic steroid. Oleandrigenin shows Na+/K+-ATP-ase inhibiting and cytotoxic activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 465-15-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11690. | |
| Oleandrin | Oleandrin (PBI-05204) inhibits the Na+, K+-ATPase activity with an IC50 of 620 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PBI-05204. CAS No. 465-16-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13719. | |
| Oleanolic acid | Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oleanic acid; Caryophyllin. CAS No. 508-02-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0156. | |
| Oleanonic acid | Oleanonic acid (3-Oxooleanolic acid) is an orally available triterpene that has anti-inflammatory and insecticidal properties. In vitro, oleanonic acid can improve oxidative stress, autophagy defects, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress induced by Amyloid-β, and in vivo, it can alleviate myocardial hypertrophy in rats[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Oxooleanolic acid. CAS No. 17990-42-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N1487. | |
| Oleclumab | Oleclumab (MEDI9447) is a human IgG1λ monoclonal antibody targeting CD73 and inhibits the exonuclease activity of the extracellular enzyme CD73. Oleclumab can adjust the composition of bone marrow and lymphoid infiltrating leukocyte populations in the tumor microenvironment and has anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEDI9447. CAS No. 1803176-05-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99039. | |
| Oleic acid | Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9-cis-Octadecenoic acid; 9Z-Octadecenoic acid. CAS No. 112-80-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg; 1 g; 5 g; 10 g. Product ID: HY-N1446. | |
| Oleic acid-13C | Oleic acid-13C is the 13C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9-cis-Octadecenoic acid-13C; 9Z-Octadecenoic acid-13C. CAS No. 82005-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N1446S. | |
| Oleic acid-13C18 | Oleic acid-13C18 is the 13C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9-cis-Octadecenoic acid-13C18; 9Z-Octadecenoic acid-13C18. CAS No. 287100-82-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1446S2. | |
| Oleic acid-d17 | Oleic acid-d17 is the deuterium labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9-cis-Octadecenoic acid-d17; 9Z-Octadecenoic acid-d17. CAS No. 223487-44-3. Pack Sizes: 500 μg (16.69 mM * 100 μL in Methyl acetate); 1 mg (16.69 mM * 200 μL in Methyl acetate). Product ID: HY-N1446S3. | |
| Oleic acid-d2 | Oleic acid-d2) is the deuterium labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]]. Oleic acid is a Na+/K+ ATPase activator[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9-cis-Octadecenoic acid-d2; 9Z-Octadecenoic acid-d2. CAS No. 5711-29-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1446S1. | |
| Oleic acid sodium | Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium[1]. Sodium oleate is a Na+/K+ ATPase activator[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium oleate; 9-cis-Octadecenoic acid sodium; 9Z-Octadecenoic acid sodium. CAS No. 143-19-1. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N1446B. | |
| Oleocanthal | Oleocanthal is an orally active phenolic seciridoid compound. Oleocanthal can be extracted from olive oil. Oleocanthal inhibits COX-1 and COX-2, reduces ROS and NO, and upregulates Nrf-2 and HO-1. Oleocanthal reduces Aβ deposition. Oleocanthal exhibits anti-Leishmania activity against promastigotes and amastigotes of L. major, with IC50 values of 18.7 and 87 μg/mL, respectively. Oleocanthal exhibits anticancer activity against colon, breast, liver, and melanoma cancers. Oleocanthal also exhibits anti-inflammatory and neuroprotective properties. Oleocanthal can be used in Alzheimer's disease research[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 289030-99-5. Pack Sizes: 5 mg. Product ID: HY-124481. | |
| Oleoside 11-methyl ester | Oleoside 11-methyl ester is a secoiridoid glucoside and possesses a strong cytotoxic activity against Hep-G2 cells[1]. Uses: Scientific research. Category: Natural products. CAS No. 60539-23-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N8882. | |
| Oleoylcarnitine-d9 | Oleoylcarnitine-d9 is deuterium labeled Oleoylcarnitine. Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation[1][1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2847775-85-1. Pack Sizes: 1 mg. Product ID: HY-113261S. | |
| Oleoylethanolamide | Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Oleoylethanolamide; Oleamide MEA; Oleic acid monoethanolamide. CAS No. 111-58-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107542. | |
| Oleoyl ethyl amide | Oleoyl ethyl amide (N-Ethyloleamide) is a fatty acid amide hydrolase (FAAH) inhibitor. Oleoyl ethyl amide can counteract bladder overactivity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Ethyloleamide. CAS No. 85075-82-7. Pack Sizes: 1 mg (32.31 mM * 100 μL in Methyl acetate); 5 mg (32.31 mM * 500 μL in Methyl acetate). Product ID: HY-120961. | |
| Oleuropein | Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity[1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32619-42-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0292. | |
| Oleuropein Aglycone | Oleuropein Aglycone (3,4-DHPEA-EA) is a polyphenol and the aglycone form of oleuropein (HY-N0292), formed by enzymatic, acidic or acetylated hydrolysis of oleuropein. Dietary intake of oleuropein Aglycone (50 mg/kg diet) increases the number of neuronal autophagic vesicles, reverses cognitive deficits in the TgCRND8 transgenic mouse model of Alzheimer's disease, and reduces the levels of histone deacetylase 2 (HDAC2) in the cortex and hippocampus. Oleuropein Aglycone increases urinary norepinephrine, interscapular brown adipose tissue epinephrine, and UCP1 protein levels, and reduced plasma leptin levels and total abdominal adipose tissue weight in a rat model of high-fat diet-induced obesity. Oleuropein Aglycone also reduced lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3,4-DHPEA-EA. CAS No. 31773-95-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-135115. | |
| Oleuropein (Standard) | Oleuropein (Standard) is the analytical standard of Oleuropein. This product is intended for research and analytical applications. Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity[1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32619-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0292R. | |
| Oleuroside | Oleuroside is a phenolic secoiridoid in olive. Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing[1]. Uses: Scientific research. Category: Natural products. CAS No. 116383-31-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6906. | |
| Oleylamine, 80-90% | Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a multifunctional reagent used for metal ion coordination and nanoparticle surface modification, and acts as a solvent, surfactant and reducing agent in the synthesis of metal oxide nanoparticles. Oleylamine, 80-90% regulates nanoparticle morphology, magnetization intensity and water proton relaxation rate via thiol-ene "click" reaction, and enhances the colloidal stability of nanoparticles in organic reagents. Oleylamine, 80-90% is mainly used in research and applications in fields such as nanomaterial synthesis, biomedical imaging (MRI contrast agents, fluorescent probes), cancer cell targeting and drug delivery[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: cis-1-Amino-9-octadecene, 80-90%. CAS No. 112-90-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g. Product ID: HY-W011696. | |
| Oleyl bromide | Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound that can carry out ring-opening reaction through a process called "encapsulation". Oleyl bromine can also be used as the starting material in the synthesis of oleylphosphonates. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (Z)-1-Bromooctadec-9-ene. CAS No. 6110-53-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W011238. | |
| Olezarsen | Olezarsen (ISIS 678354;IONIS-APOCIII-LRx) is a GalNAc-modified antisense oligonucleotide. Olezarsen binds to APOC3 mRNA and induces its degradation via ribonuclease H1-mediated sense strand cleavage, thereby reducing hepatic apolipoprotein C-III (apoC-III) synthesis. Olezarsen reduces plasma triglyceride, apolipoprotein B and non-high-density lipoprotein cholesterol levels. Olezarsen is applicable to research related to familial chylomicronemia syndrome, hypertriglyceridemia and atherosclerotic cardiovascular disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS 678354; IONIS-APOCIII-LRx; AKCEA-APOCIII-LRx. CAS No. 2097587-83-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153491. | |
| Olezarsen sodium | Olezarsen (ISIS 678354;IONIS-APOCIII-LRx) sodium is a GalNAc-modified antisense oligonucleotide. Olezarsen sodium binds to APOC3 mRNA and induces its degradation via ribonuclease H1-mediated sense strand cleavage, thereby reducing hepatic apolipoprotein C-III (apoC-III) synthesis. Olezarsen sodium reduces plasma triglyceride, apolipoprotein B and non-high-density lipoprotein cholesterol levels. Olezarsen sodium is applicable to research related to familial chylomicronemia syndrome, hypertriglyceridemia and atherosclerotic cardiovascular disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS 678354 sodium; IONIS-APOCIII-LRx sodium; AKCEA-APOCIII-LRx sodium. CAS No. 2298451-31-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153491A. | |
| Oligomycin | Oligomycin, an antifungal antibiotic, is an inhibitor of H+-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1404-19-9. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6782. | |
| Oligomycin A | Oligomycin A (MCH 32), created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCH 32. CAS No. 579-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16589. | |
| Oligomycin B | Oligomycin B is an antibiotic that acts as a non-selective inhibitor of ATP Synthase. Oligomycin B increases mitochondrial membrane potential. Oligomycin B induces apoptosis and necrosis. Oligomycin B impairs the motility of Plasmopara viticola zoospores and induces their lysis. Oligomycin B inhibits Magnaporthe oryzae (wheat blast fungus) and suppresses the development of wheat blast. Oligomycin B reduces hyphal growth and spore germination of Botrytis cinerea, and protects Arabidopsis thaliana against Botrytis cinerea infection. Oligomycin B exacerbates cytotoxic brain edema in rats with cerebral cortical contusion, increases intracranial pressure and brain water content, and aggravates mitochondrial damage in these rats. Oligomycin B is used in studies related to grape downy mildew, traumatic brain injury, wheat blast, and gray mold[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 11050-94-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6784. | |
| Oligopeptide-68 | Oligopeptide-68 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1206525-47-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5251. | |
| Oligopeptide P11-4 | Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent[1]. Uses: Scientific research. Category: Peptides. CAS No. 593266-60-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10294. | |
| O-Linked GlcNAc transferase substrate | O-Linked GlcNAc transferase substrate is a biological active peptide. (A peptide substrate of O-linked GlcNAc transferase (OGT), a eukaryotic glycosyltransferase that uses UDP-GlcNAc as a glycosyl donor.). Uses: Scientific research. Category: Peptides. CAS No. 954381-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5375. | |
| Olitigaltin | TD139 is a synthetic galectin-3 inhibitor. TD139 has high affinity for galectin-3 with a Kd of 68 nM, a Kd of 0.22 μM for galectin-1, and a Kd of 38 μM for galectin-7[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TD139; GB0139. CAS No. 1450824-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19940. | |
| Olive oil | Olive oil (Cropure OL) is an oleaginous compound found in the fruit of the Olea europaea tree. Olive oil contains many phenolic components and exerts antioxidant activity. Olive oil exhibits hydroxyl radical scavenging, platelet aggregation inhibition and xanthine oxidase inhibitory activity. Olive oil can promote wound healing and relieve inflammation. Olive oil can be used for the research of inflammation, cancer, metabolic and cardiovascular disease, such as diabetic foot ulcers and inflammatory bowel disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cropure OL. CAS No. 8001-25-0. Pack Sizes: 50 mL; 100 mL. Product ID: HY-108749. | |
| Olmesartan | Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RNH-6270. CAS No. 144689-24-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-17004. | |
| Olmesartan medoxomil | Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CS 866. CAS No. 144689-63-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17005. | |
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