MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Orvepitant maleate | Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pKi of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GW823296 maleate. CAS No. 579475-24-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122347A. |  |
| Oryzalin | Oryzalin is a dinitroaniline herbicide with antimitotic and antileishmanial activities. Oryzalin can bind to plant tubulin, inhibit the polymerization of microtubules in plant cells, and affect chromosome migration. Oryzalin can also be used to induce chromosome doubling[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19044-88-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-147092. | |
| Orziloben | Orziloben is a medium chain fatty acid (MCFA) analogue[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1555822-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156629. | |
| Osanetant | Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SR142801. CAS No. 160492-56-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14551. | |
| Osavampator | Osavampator (TAK-653) is a AMPA receptor positive allosteric modulator. Osavampator selectively binds to AMPA-R in a glutamate-dependent manner and induces Ca2+ influx in hGluA1i CHO cells (EC50 = 3.3 μM). Osavampator improves learning and memory in many models. Osavampator is can be used for the research of depressive disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-653; NBI-1065845. CAS No. 1358751-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115864. | |
| OSBPL7-IN-1 | OSBPL7-IN-1 is an orally active oxysterol binding protein like 7 (OSBPL7) inhibitor. OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1269826-44-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143200. | |
| Oseltamivir | Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS 4104. CAS No. 196618-13-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13317. | |
| Oseltamivir acid | Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses. Oseltamivir acid has an extremely weak ability to penetrate the BBB under normal physiological conditions, but its blood-brain barrier penetration is significantly enhanced under inflammatory conditions[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS 4071; Ro 64-0802; Oseltamivir carboxylate. CAS No. 187227-45-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13318. | |
| Oseltamivir acid hydrochloride | Oseltamivir acid hydrochloride is an active metabolite of the antiviral agent Oseltamivir (HY-13317) ethylester. Oseltamivir acid hydrochloride belongs to baseline toxicants in toxicity ratio analysis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS 4071 hydrochloride; Ro 64-0802 hydrochloride; Oseltamivir carboxylate hydrochloride. CAS No. 1415963-60-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13318A. | |
| Oseltamivir-d3 | Oseltamivir-d3 is a deuterium labeled Oseltamivir. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093851-61-6. Pack Sizes: 1 mg. Product ID: HY-13317S. | |
| Oseltamivir phosphate | Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS 4104 phosphate. CAS No. 204255-11-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-17016. | |
| Oseltamivir (Standard) | Oseltamivir (Standard) is the analytical standard of Oseltamivir. This product is intended for research and analytical applications. Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS 4104 (Standard). CAS No. 196618-13-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13317R. | |
| Osemitamab | Osemitamab is an IgG1 antibody targeting to human claudin-18.2. Osemitamab consists of human-Mus musculus monoclonal TST001 γ1-chain, disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer (ACI). Osemitamab in combination with Capecitabine (HY-B0016) and Oxaliplatin (HY-17371), can be used for G/GEJ cancer study[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TST001. CAS No. 2460539-61-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9991. | |
| OSI-027 | OSI-027 (ASP7486) is a potent, selective, orally active and ATP-competitive mTOR kinase activity inhibitor with an IC50 of 4 nM. OSI-027 targets both mTORC1 and mTORC2 with IC50s of 22 nM and 65 nM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP7486. CAS No. 936890-98-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10423. | |
| OSI-930 | OSI-930 is an orally selective inhibitor of Kit, KDR and CSF-1R (c-Fms) with IC50s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1, c-Raf, Lck and low activity against PDGFRα/β, Flt-3 and Abl. OSI-930 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 728033-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10204. | |
| Osilodrostat | Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LCI699. CAS No. 928134-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276. | |
| Osilodrostat phosphate | Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LCI699 phosphate. CAS No. 1315449-72-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276A. | |
| Osimertinib | Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9291; Mereletinib. CAS No. 1421373-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15772. | |
| Osimertinib-d6 | Osimertinib-d6 is a deuterium labeled osimertinib. Osimertinib is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9291-d6; Mereletinib-d6. CAS No. 1638281-44-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15772S. | |
| Osimertinib dimesylate | Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9291 dimesylate; Mereletinib dimesylate. CAS No. 2070014-82-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-79077. | |
| Osimertinib mesylate | Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9291 mesylate; Mereletinib mesylate. CAS No. 1421373-66-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15772A. | |
| Osimertinib (Standard) | Osimertinib (Standard) is the analytical standard of Osimertinib. This product is intended for research and analytical applications. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9291 (Standard); Mereletinib (Standard). CAS No. 1421373-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15772R. | |
| Osivelotor | Osivelotor is an orally effective small molecule. Osivelotor is an allosteric regulator of deoxyhemoglobin S (HbS). Osivelotor increases the affinity of HbS to oxygen, inhibits HbS polymerization, and thus prevents erythrocyte sickling in the blood. Osivelotor can be used for research of sickle cell disease (SCD) [1] [2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GBT-601; GBT-021601. CAS No. 2417955-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148788. | |
| OSMI-1 | OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1681056-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-119738. | |
| OSMI-4 | OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 2260791-14-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114361. | |
| Osocimab | Osocimab (BAY 1213790), an anti-FXIa antibody (Ki=2.4 nM; EC50=0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 1213790. CAS No. 2056878-75-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99794. | |
| Ospemifene | Ospemifene (FC-1271a) is an orally active and non-estrogenic selective estrogen receptor modulator (SERM) with Ki values of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene inhibits caspase-3 activity. Ospemifene inhibits neuronal degeneration, prevents bone loss, and increases vaginal weight and vaginal epithelial height. Ospemifene has anticancer activity against breast cancer[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FC-1271a. CAS No. 128607-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0723. | |
| OSS_128167 | OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 887686-02-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107454. | |
| Ostarine | Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-2866; GTX-024; Enobosarm. CAS No. 841205-47-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13273. | |
| Osteocalcin (human) | Osteocalcin (Osteocalcin (1-49)) (human) is a vitamin K-dependent bone specific protein. Osteocalcin (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Osteocalcin (1-49) (human). CAS No. 136461-80-8. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-P2588. | |
| Osteogenic Growth Peptide (10-14) | Osteogenic Growth Peptide (10-14) (OGP(10-14)), the C-terminal truncated pentapeptide of osteogenic growth peptide (OGP), retains the full OGP-like activity. Osteogenic Growth Peptide (10-14) is responsible for the binding to the OGP receptor and activates an intracellular Gi-protein-MAP kinase signaling pathway. Osteogenic Growth Peptide (10-14) is a potent mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acts as a Src inhibitor[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OGP(10-14); Historphin. CAS No. 105250-85-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107024. | |
| Osthenol | Osthenol (Ostenol) is a reversible, selective, competitive inhibitor of hMAO-A (IC50=0.74 μM, Ki=0.26 μM), with antifungal and antibacterial activity. Osthenol inhibits the oxidative deamination of hMAO-A and regulates the metabolism of monoamine neurotransmitters. Osthenol also inhibits the PI3K/AKT signaling pathway to induce apoptosis of colon cancer cells, arrest the cell cycle at the G1 phase, and inhibit cell proliferation. Osthenol is mainly used in the study of neurological diseases and cancer, especially depression-related MAO-A targeted intervention and colon cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ostenol. CAS No. 484-14-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N2554. | |
| Osthole | Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Osthol; NSC 31868. CAS No. 484-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0054. | |
| Ostruthin | Ostruthin is a natural coumarin compound with bacterial and antimycobacterial activities. Ostruthin inhibits the growth of mycobacteria and Staphylococcus aureus. Ostruthin suppresses vascular smooth muscle cell proliferation as well as de novo cellular DNA synthesis. Ostruthin is applicable to research related to mycobacterial infections and cardiovascular and cerebrovascular diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ostruthine. CAS No. 148-83-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W506116. | |
| OSU-03012 | OSU-03012 (AR-12; PDK1 inhibitor AR-12) is a blood-brain permeable PDK-1 inhibitor with an IC50 of 5 μM[1][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AR-12; PDK1 inhibitor AR-12. CAS No. 742112-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10547. | |
| Osunprotafib | Osunprotafib (ABBV-CLS-484) is an orally active and selective active site PTPN1 (IC50: 2.5?nM) and PTPN2(IC50: 1.8?nM) inhibitor. Osunprotafib has 6-8-fold weaker activity on PTPN9 and no detectable activity on SHP-1 or SHP-2. Osunprotafib increases the sensitivity of human cancer cell lines to IFNγ. Osunprotafib generates robust anti-tumor immunity by enhancing JAK-STAT signalling and reducing T?cell dysfunction[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABBV-CLS-484. CAS No. 2489404-97-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145923. | |
| OSu-PEG4-VC-PAB-MMAE | OSu-PEG4-VC-PAB-MMAE involves in GDP-FAmP4MMAE (Monomethylauristatin E) synthesis, which is for GDP label via site-specific conjugation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2762518-86-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148426. | |
| OSU-T315 | OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain)[1]. OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner[2]. OSU-T315 causes cell death through apoptosis and autophagy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2070015-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18676. | |
| OSW-1 | OSW-1, isolated from Ornithogalum caudatum, is a specific antagonist of ooxysterol binding protein (OSBP) and OSBP-related protein 4 (ORP4) with GI50s in the nanomolar range in human cancer lines. Uses: Scientific research. Category: Signaling pathways. CAS No. 145075-81-6. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-101213. | |
| OT-82 | OT-82 is a potent, selective and orally active inhibitor of NAMPT. OT-82 is selectively toxic to cells of hematopoietic origin and?induces cell death in a NAD+ dependent manner. OT-82 is a promising antineoplastic agent for the study of hematological malignancies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800487-55-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-136241. | |
| Otelixizumab | Otelixizumab (ChAglyCD3) is an anti-human CD3 monoclonal antibody and can be used for the research of type 1 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ChAglyCD3; TRX 4. CAS No. 881191-44-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99211. | |
| Otenabant | Otenabant is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-945598. CAS No. 686344-29-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10871. | |
| Otenzepad | Otenzepad (AF-DX 116) is a selective and competitive M2 muscarinic acetylcholine receptor antagonist, with IC50 values of 640 nM and 386 nM for rabbit peripheral lung and rat heart, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AF-DX 116. CAS No. 102394-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101381. | |
| O-(tert-Butyl)-L-serine | O-(tert-Butyl)-L-serine is a serine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18822-58-7. Pack Sizes: 10 mM * 1 mL in Water; 10 g; 25 g; 100 g; 500 g. Product ID: HY-W010156. | |
| O-(tert-Butyl)-N-Fmoc-L-allothreonine | O-(tert-Butyl)-N-Fmoc-L-allothreonine is a threonine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 201481-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-W006923. | |
| Oteseconazole | Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VT-1161. CAS No. 1340593-59-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17643. | |
| Otlertuzumab | Otlertuzumab (TRU-016) is a humanized anti-CD37 monoclonal antibody that can be used for cancer research[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: TRU-016. CAS No. 1372645-37-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99212. | |
| OTS186935 | OTS186935 is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 regulates the production of γ-H2AX in cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093400-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122181. | |
| OTS193320 | OTS193320, a imidazo[1,2-a]pyridine compound, is a SUV39H2 methyltransferase activity inhibitor. OTS193320 decreases global histone H3 lysine 9 tri-methylation levels in breast cancer cells and triggers apoptotic cell death. Combination of OTS193320 with Doxorubicin (HY-15142A) results in reduction of γ-H2AX levels as well as cancer cell viability compared to a single agent OTS193320 or DOX[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093401-33-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-122182. | |
| OTS514 | OTS514 is a highly potent TOPK inhibitor with an IC50 of 2.6 nM. OTS514 strongly suppresses the growth of TOPK-positive cancer cells[1]. OTS514 induces cell cycle arrest and apoptosis[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1338540-63-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18621. | |
| OTS964 hydrochloride | OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM[1]. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1338545-07-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12467. | |
| OTSSP167 | OTSSP167 (OTS167) is a highly potent and ATP-competitive MELK inhibitor with IC50 value of 0.41 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OTS167. CAS No. 1431697-89-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-15512. | |
| OTSSP167 hydrochloride | OTSSP167 (OTS167) hydrochloride is a highly potent and ATP-competitive MELK inhibitor with IC50 value of 0.41 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OTS167 hydrochloride. CAS No. 1431698-10-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15512A. | |
| OTUB1/USP8-IN-1 | OTUB1/USP8-IN-1 is a potent dual OTUB1/USP8 inhibitor with IC50 values of 0.17 and 0.28 nM for OTUB1 and USP8, respectively. OTUB1/USP8-IN-1 can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2858800-98-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151563. | |
| OTX008 | OTX008 is a selective inhibitor of galectin-1. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Calixarene 0118; PTX008. CAS No. 286936-40-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19756. | |
| OU749 | OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 μM. OU749 shows cytotoxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 519170-13-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-126710. | |
| OUL232 | OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 943119-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148566. | |
| OUL35 | OUL35 (NSC39047) is a potent and selective inhibitor of ARTD10 (PARP-10), with an IC50 of 329 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC39047. CAS No. 6336-34-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123512. | |
| OV329 hydrochloride | OV329 hydrochloride is a potent GABA aminotransferase inactivator. OV329 hydrochloride is a Vigabatrin (HY-15399) analogue. OV329 hydrochloride can increase brain GABA levels and block abnormal intracerebral hyperexcitability. OV329 hydrochloride exhibits anticonvulsant and antiepileptic activities. OV329 hydrochloride can be used for the research of neurological disease, such as seizure[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093928-29-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-179215. | |
| OVA (257-264), scrambled | OVA (257-264), scrambled is a biological active peptide. (Out-of-order control peptide of HY-P1489). Uses: Scientific research. Category: Peptides. CAS No. 1213245-88-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5400. | |
| OVA-E1 peptide TFA | OVA-E1 peptide TFA, is an antagonist variant of SIINFEKL [OVA (257-264). OVA-E1 peptide, activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1262750-80-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2319A. | |
| Ovalbumin, low endotoxin | Ovalbumin, low endotoxin (OVA, low endotoxin), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues[1]. Ovalbumin, a low endotoxin, can be used to establish an asthma model[2][3]. Uses: Scientific research. Category: Induced disease models products. CAS No. 9006-59-1. Pack Sizes: 5 mg. Product ID: HY-W250978A. | |
| Ovalbumins | Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues[1]. We recommend using Ovalbumin, low endotoxin (HY-W250978A) to establish an asthma model. Uses: Scientific research. Category: Signaling pathways. CAS No. 9006-59-1. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W250978. | |
| OVA peptide | OVA peptide mainly exists in egg white, it is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA peptide has been widely studied in allergy research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 141312-45-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3715. | |
| OVA Peptide(257-264) | OVA Peptide(257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb. Uses: Scientific research. Category: Signaling pathways. CAS No. 138831-86-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1489. | |
| OVA Peptide(257-264) TFA | OVA Peptide(257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb. Uses: Scientific research. Category: Signaling pathways. CAS No. 1262751-08-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1489A. | |
| OVA Peptide (323-339) | OVA Peptide (323-339) represents a T and B cell epitope of Ovalbumin (Ova), which is important in the generation and development of immediate hypersensitivity responses in BALB/c mice. Uses: Scientific research. Category: Induced disease models products. CAS No. 92915-79-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0286. | |
| OVA-Q4 Peptide | OVA-Q4 Peptide is a biological active peptide. (Q4 Peptide (SIIQFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).). Uses: Scientific research. Category: Signaling pathways. CAS No. 148274-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5410. | |
| OVA-T4 Peptide | OVA-T4 Peptide (SIITFEKL, OVA (257-264) Variant) is a low-affinity variant of OVA (257-264) (SIINFEKL). OVA-T4 Peptide has similar binding to H-2Kb MHC class I molecules as OVA (257-264), but has a much lower affinity for the OT-I TCR25[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SIITFEKL, OVA (257-264) Variant. CAS No. 148274-88-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5411. | |
| Oveporexton | Oveporexton (TAK-861) is an orally active and selective orexin receptor 2 (OX2R) agonist with an EC50 of 2.5 nM. Oveporexton exhibits 3000-fold selectivity for OX2R over OX1R. Oveporexton can be used for the study of hypersomnia disorders including narcolepsy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-861. CAS No. 2460722-04-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159835. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.