MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Palmitodiolein | Palmitodiolein (Triglyceride POO) is a triacylglycerol which is present in vegetable oils. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Triglyceride POO; Glycerol dioleate palmitate; 1,2-Dioleoyl-3-palmitoylglycerol. CAS No. 2190-30-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112132. |  |
| Palmitoleic acid | Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats. Uses: Scientific research. Category: Signaling pathways. CAS No. 373-49-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W011873. | |
| Palmitoleic acid-13C16 | Palmitoleic acid-13C16 is the 13C labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats. Uses: Scientific research. Category: Signaling pathways. CAS No. 2483735-57-3. Pack Sizes: 1 mg. Product ID: HY-W011873S2. | |
| Palmitoylcarnitine | Palmitoylcarnitine is an endogenous metabolite. Uses: Scientific research. Category: Signaling pathways. CAS No. 1935-18-8. Pack Sizes: 10 mM * 1 mL in Ethanol; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126357. | |
| Palmitoyl coenzyme A lithium | Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Palmitoyl CoA lithium. CAS No. 188174-64-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-134427. | |
| Palmitoylethanolamide | Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Palmidrol; Loramine P 256. CAS No. 544-31-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-20685. | |
| Palmitoylethanolamide (Standard) | Palmitoylethanolamide (Standard) is the analytical standard of Palmitoylethanolamide. This product is intended for research and analytical applications. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Palmidrol (Standard); Loramine P 256 (Standard). CAS No. 544-31-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-20685R. | |
| Palmitoyl glutamic acid | Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) is an acyl amino acid with neuroprotective effects[1]. Palmitoyl glutamic acid is used as cosmetic material[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Palmitoyl-L-glutamic acid. CAS No. 38079-66-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135094. | |
| Palmitoyl hexapeptide-12 | Palmitoyl hexapeptide-12 is a bioactive peptide. Palmitoyl hexapeptide-12 reduces IL-6. Palmitoyl hexapeptide-12 has anti-aging effects. Palmitoyl hexapeptide-12 can be used in the research of photoaging and related aging skin problems[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 171263-26-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-66015. | |
| Palmitoyl pentapeptide 4 | Palmitoyl pentapeptide 4 (Matrixyl; Palmitoyl pentapeptide 3; Matrixyl (Palmitoyl Pentapeptide) is a bioactive peptide with anti-ageing effect and has been reported used as a cosmetic ingredient[1] | |
| Palonosetron hydrochloride | Palonosetron hydrochloride is a 5-HT3 antagonist primarily used to prevent acute, delayed, and overall chemotherapy-induced nausea and vomiting. In addition, Palonosetron hydrochloride exhibits moderate anti-flavivirus activity and potent anti-Zika virus activity in mammalian cells. Palonosetron hydrochloride also possesses antidepressant activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 135729-62-3. Pack Sizes: 50 mg; 100 mg; 200 mg. Product ID: HY-A0021. | |
| Palosuran | Palosuran (ACT-058362) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran can improves pancreatic and renal function in diabetic rats[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACT-058362. CAS No. 540769-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10655. | |
| Palovarotene | Palovarotene is a nuclear retinoic acid receptor γ (RAR-γ) agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R 667; Ro 3300074. CAS No. 410528-02-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14799. | |
| Paltimatrectinib | Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PBI-200; PPI-5278. CAS No. 2353522-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145587. | |
| Palupiprant | Palupiprant (E7046) is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM. Palupiprant exhibits anti-tumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E7046. CAS No. 1369489-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103088. | |
| Palverafusp alfa | Palverafusp alfa (IMM-2510; SYN-2510) is a PD-L1/VEGF-targeting IgG1κ type humanized antibody. Palverafusp alfa blocks PD-1/PD-L1 binding, relieves immune suppression, mediates PD-L1-directed antibody-dependent cellular cytotoxicity (ADCC). Palverafusp alfa blocks VEGF/VEGFR binding, inhibits angiogenic signaling, relieves VEGF-induced immune suppression. Palverafusp alfa reduces endothelial cell proliferation, enhances ADCC and antibody-dependent cellular phagocytosis (ADCP), inhibits tumor growth, reverses T cell immune suppression. Palverafusp alfa exhibits immune stimulatory, antiangiogenic, and anti-tumor activity in the tumor microenvironment. Palverafusp alfa can be used for the research of cancer, such as solid tumors, non-small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMM-2510; SYN-2510. CAS No. 2850355-87-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990961. | |
| Pam2Cys | Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection[1][2][3][4]. UseĀ | |
| Pam3CSK4 TFA | Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pam3Cys-Ser-(Lys)4 TFA. CAS No. 112208-01-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1180A. | |
| Pamapimod | Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro4402257; R1503. CAS No. 449811-01-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10405. | |
| Pamidronate disodium | Pamidronate disodium (CGP 23339A), the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGP 23339A. CAS No. 57248-88-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0012A. | |
| Pamidronate disodium pentahydrate | Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 109552-15-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0730. | |
| Pamidronic acid | Pamidronic acid, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronic acid significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of OPG in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronic acid can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 40391-99-9. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-B0012. | |
| p-Aminophenylmercuric acetate | p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6283-24-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-148905. | |
| Pamiparib | Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor, with IC50 values of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively. Pamiparib has potent PARP trapping, and capability to penetrate the brain, and can be used for the research of various cancers including the solid tumor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BGB-290. CAS No. 1446261-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104044. | |
| PAMP-12(human, porcine) | PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 196305-05-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2198. | |
| PAMP-12 (unmodified) | PAMP-12 (unmodified) is an endogenous peptide and is a MrgX2 agonist. PAMP-12 (unmodified) can reduce cAMP accumulation, increase Ca2+ levels, enhance beta-arrestin recruitment, decrease IP-1, and increases phosphoERK. PAMP-12 (unmodified) can elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. PAMP-12 (unmodified) can be used for the research of hypotension and ulcerative colitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 929905-12-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3419. | |
| Panaxatriol | Panaxatriol is an orally active insulin sensitizer. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32791-84-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-N0597. | |
| Pancreatic Polypeptide, human | Pancreatic Polypeptide, human is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Human pancreatic polypeptide. CAS No. 75976-10-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P0199. | |
| Pancreatin | Pancreatin is the porcine pancreas extract (PPE) which contains the main pancreatic digestive enzymes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 8049-47-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B2118. | |
| Pancuronium dibromide | Pancuronium dibromide, a bis-quaternary steroid, is a neuromuscular relaxant. Pancuronium dibromide inhibits neuromuscular transmission by competing with acetylcholine for binding sites on nACh receptors. Pancuronium dibromide also inhibits cardiac muscarinic receptors and has a sympathomimetic action[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15500-66-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0429. | |
| pan-HCN-IN-1 | pan-HCN-IN-1 (Compound J&J12e) is an inhibitor for hyperpolarization-activated and cyclic-nucleotide-gated 1 (HCN1) ion channel, with IC50 of 58 nM. pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rats brain slices[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334308-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163455. | |
| p-Anisic acid | p-Anisic acid (4-Methoxybenzoic acid) is an orally available tyrosinase inhibitor that has antioxidant, anti-anxiety, anti-inflammatory, anti-tumor, anti-diabetic, and preservative properties. p-Anisic acid can be used as a preservative in the cosmetics field[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Methoxybenzoic acid; Draconic acid. CAS No. 100-09-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N1394. | |
| Panitumumab | Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABX-EGF. CAS No. 339177-26-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99041. | |
| Pan KRas-IN-1 | Pan KRas-IN-1 is a pan KRas inhibitor, can be used for agent resistance in cancer developed with KRas G12C inhibitors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2791263-84-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148098. | |
| pan-KRAS-IN-18 | pan-KRAS-IN-18 is a panKRAS inhibitor that inhibits KRAS WT and KRAS G12V with IC50s of 29 and 9 nM, respectively. pan-KRAS-IN-18 exhibits antiproliferative activity in KRAS-mutant cell lines. pan-KRAS-IN-18 can be used for lung cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2937327-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162960. | |
| Panobacumab | Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of P. aeruginosa[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KBPA101. CAS No. 885053-97-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99214. | |
| Panobinostat | Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LBH589; NVP-LBH589. CAS No. 404950-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10224. | |
| Panobinostat lactate | Panobinostat lactate is a potent and orally active non-selective HDAC inhibitor. Panobinostat lactate has antineoplastic activities. Panobinostat lactate effectively disrupts HIV latency. Panobinostat lactate induces cell apoptosis and autophagy. Panobinostat lactate can be used for the study of refractory or relapsed multiple myeloma[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LBH589 lactate; NVP-LBH589 lactate. CAS No. 960055-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10224A. | |
| Panobinostat (Standard) | Panobinostat (Standard) (LBH589 (Standard)) is the analytical standard of Panobinostat (HY-10224). This product is intended for research and analytical applications. Panobinostat is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LBH589 (Standard); NVP-LBH589 (Standard). CAS No. 404950-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10224R. | |
| Pan-RAS-IN-1 | Pan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors. Uses: Scientific research. Category: Signaling pathways. CAS No. 1835283-94-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101295. | |
| Pan-RAS-IN-2 | Pan-rasin-2 (compound 6A) is an orally active molecular glues that targets RAS. Pan-RAS-IN-2 inhibits pERK (IC50 in AsPC-1 cells: 0.3 nM). Pan-rasin-2 has significant inhibitory activity on cell proliferation of RAS mutant cell lines. Pan-rasin-2 can form ternary complexes with cyclophilin A (CYPA) and RAS (ON) proteins and the formation of ternary complexes can block the binding of RAF downstream of RAS, which has anti-tumor (such as colorectal cancer, pancreatic cancer) effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3034673-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158409. | |
| Pantethine | Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Pantethine; LBF disulfide. CAS No. 16816-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B1028. | |
| Pantoic acid sodium | Sodium pantoate is a biosynthetic intermediate. Sodium pantoate is generated via hydroxymethylation of α-ketoisovalerate followed by reduction. Sodium pantoate combines with β-alanine via an amide bond to form pantothenic acid. Pantothenic acid has important biological significance[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60979-68-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W579377. | |
| Pantoprazole | Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BY1023; SKF96022. CAS No. 102625-70-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-17507. | |
| Pantoprazole sodium | Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole sodium, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BY1023 sodium; SKF96022 sodium. CAS No. 138786-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-17507A. | |
| Pantothenate-AMC | Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1224691-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-169491. | |
| Pantothenate kinase-IN-2 | Pantothenate kinase-IN-2 is a pantothenate kinase inhibitor with IC50 values of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3. Pantothenate kinase-IN-2 can bind specifically to the ATP-PanK3 complex and block CoA biosynthesis. Pantothenate kinase-IN-2 can be used for the research of pank-associated neurodegeneration and type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902614-04-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-44170. | |
| Pantothenic acid-13C3,15N hemicalcium | Pantothenic acid-13C3,15N (hemicalcium) is the 13C-labeled and 15N-labeled D-Pantothenic acid. D-Pantothenic acid is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 356786-94-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0430S. | |
| PAP-1 | PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC50=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-(4-Phenoxybutoxy)psoralen. CAS No. 870653-45-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10015. | |
| PAP-1 (Standard) | PAP-1 (Standard) is the analytical standard of PAP-1. This product is intended for research and analytical applications. PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC50=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-(4-Phenoxybutoxy)psoralen (Standard). CAS No. 870653-45-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10015R. | |
| Papain | Papain is a cysteine protease of the peptidase C1 family. Papain enhances red cell agglutination by anti-D and anti-A, and increases red cell sensitivity to K cell-mediated lysis in ADCC assays. Papain can induce pulmonary emphysema. Papain can be used for the researches of Rh haemolytic disease of the newborn and pulmonary emphysema[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-73-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-P1645. | |
| Papain (1.5-10 units/mg) | Papain (1.5-10 units/mg) is a cysteine protease of the peptidase C1 family. Papain (1.5-10 units/mg) enhances red cell agglutination by anti-D and anti-A, and increases red cell sensitivity to K cell-mediated lysis in ADCC assays. Papain (1.5-10 units/mg) can induce pulmonary emphysema. Papain (1.5-10 units/mg) can be used for the researches of Rh haemolytic disease of the newborn and pulmonary emphysema[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-73-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-P1645A. | |
| Papain inhibitor | Papain inhibitor (Glycylglycyl-L-tyrosyl-L-arginine) is a competitive papain-targeting enzyme inhibitor with a Ki of 9 μM. Papain inhibitor binds directly to the substrate binding site of papain, inhibiting substrate hydrolysis by the enzyme. Papain inhibitor functions as a component of an electrochemical probe for the detection of papain[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycylglycyl-L-tyrosyl-L-arginine. CAS No. 70195-20-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1315. | |
| Paprotrain | Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 57046-73-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101298. | |
| Paquinimod | Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABR-215757; ABR 25757. CAS No. 248282-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100442. | |
| PAR-4 (1-6) amide (human) | PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 245443-51-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4004. | |
| PAR-4 Agonist Peptide, amide | PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAR-4-AP; AY-NH2. CAS No. 352017-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1309. | |
| PAR-4 Agonist Peptide, amide TFA | PAR-4 Agonist Peptide, amide TFA (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAR-4-AP TFA; AY-NH2 TFA. CAS No. 1228078-65-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1309A. | |
| Para-aminoblebbistatin | Para-aminoblebbistatin is the inhibitor for myosin II. Para-aminoblebbistatin inhibits the ATPase activity of myosin II, thereby blocking the formation and contraction of the actin-myosin network. Para-aminoblebbistatin is a non-fluorescent and photostable Blebbistatin (HY-13813) derivative[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2097734-03-5. Pack Sizes: 500 μg. Product ID: HY-111474. | |
| Paradol | Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site. Uses: Scientific research. Category: Signaling pathways. Alternative Names: [6]-Gingerone; [6]-Paradol. CAS No. 27113-22-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-14617. | |
| para-Nitroblebbistatin | para-Nitroblebbistatin is a derivative of Blebbistatin (HY-13813) and an inhibitor of myosin II. para-Nitroblebbistatin is photostable, non-cytotoxic, and non-phototoxic. para-Nitroblebbistatin can serve as an ideal substitute for Blebbistatin (HY-13813) to study the role of myosin II in physiology, development, and cell biology[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1621326-32-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120870. | |
| Pararosaniline hydrochloride | Pararosaniline hydrochloride (Basic red 9) is a pH-responsive basic dye, as a biological stain to track certain proteins. The pH of the acidified Pararosaniline hydrochloride reagent has a significant effect on the color and the maximum absorption wavelength (λmax) of the reaction system, with its optimum pH 0.48 and a λmax at 549?nm. Pararosaniline hydrochloride is also a strong modifier of RNA splicing. Pararosaniline hydrochloride has been used in the analysis of SO2 and formaldehyde and staining of bacteria or other organisms. Pararosaniline hydrochloride is extensively used in industries like textile, printing, paper, cosmetic, and leather[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Basic red 9. CAS No. 569-61-9. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g. Product ID: HY-W127770. | |
| Parathyroid hormone (1-34) (rat) | Parathyroid hormone (1-34) (rat) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 98614-76-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2279. | |
| Paraxanthine | Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels. Uses: Scientific research. Category: Signaling pathways. CAS No. 611-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W016498. | |
| Paraxanthine-d6 | Paraxanthine-d6 is the deuterium labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels. Uses: Scientific research. Category: Signaling pathways. CAS No. 117490-41-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-W016498S. | |
| Parbendazole | Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF 29044. CAS No. 14255-87-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115364. | |
| Parecoxib Sodium | Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor that is permeable to the blood-brain barrier, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SC 69124A. CAS No. 198470-85-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-17474A. | |
| PARG-IN-4 | PARG-IN-4 (Formula (A)) is an orally available PARG inhibitor (EC50=1.9 nM) with cell membrane permeability. PARG-IN-4 can effectively inhibit tumor growth in mouse models. PARG-IN-4 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2988890-20-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156881. | |
| Pargyline | Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively. Pargyline has antihypertensive and anticancer activities[1][2][3]. Pargyline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 555-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-A0091A. | |
| Paricalcitol | Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure. Uses: Scientific research. Category: Signaling pathways. CAS No. 131918-61-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50919. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.