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Penpulimab
Penpulimab is an IgG1 backbone anti-PD-1 monoclonal antibody with antitumor activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AK-105. CAS No. 2350298-92-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99108.
Pent-4-yn-1-amine
Pent-4-yn-1-amine is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 15252-44-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W597413.
Pent-4-ynal
Pent-4-ynal is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 18498-59-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W612158.
Pentabromopseudilin
Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10245-81-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113604.
Pentachloropseudilin
Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC50s range from 1 to 5 μM for mammalian class-1 myosins and greater than 90 μM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-β (TGF-β)-stimulated signaling, with an IC50 of 0.1 to 0.2 μM for TGF-β[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Antibiotic A 15104 Y; PClP. CAS No. 69640-38-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115669.
Pentaethylene glycol
Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4792-15-8. Pack Sizes: 5 g; 10 g; 25 g; 100 g; 500 g. Product ID: HY-W007341.
Pentagalloylglucose
Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose. CAS No. 14937-32-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0527.
Pentagastrin
Pentagastrin (ICI-50123) is a potent, selective Cholecystokinin B (CCKB) receptor agonist with an EC50 value of 11 nM. Pentagastrin enhances gastric mucosal defense mechanisms against acid and protects the gastric mucosa from experimental injury[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ICI-50123. CAS No. 5534-95-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0261.
Pentaglycine
Pentaglycine (Tetraglycylglycine; NSC 96353) is a bridging structure composed of five glycine residues. Pentaglycine serves as a characteristic peptidoglycan cross-bridge component of staphylococci and a specific substrate for lysostaphin. Pentaglycine maintains the integrity of the peptidoglycan cell wall of Staphylococcus aureus via peptide chain cross-linking and regulates bacterial growth. Pentaglycine expression is downregulated in high-glucose environments, inhibiting bacterial proliferation. Pentaglycine can be applied to studies related to Staphylococcus aureus infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tetraglycylglycine; Gly-Gly-Gly-Gly-Gly; NSC 96353. CAS No. 7093-67-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W141916.
Pentamidine
Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MP-601205. CAS No. 100-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0537.
Pentamidine isethionate
Pentamidine isethionate (MP-601205 isethionate) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine isethionate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine isethionate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine isethionate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MP-601205 isethionate. CAS No. 140-64-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B0537B.
Pentetic acid
Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diethylenetriaminepentaacetic acid; DTPA. CAS No. 67-43-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1335.
Pentetreotide
Pentetreotide is a diethylenetriaminopentaacetic (DTPA) conjugate of Octreotide (HY-P0036). Pentetreotide is a somatostatin analog that, when labeled with 111In, can be used for nuclear medicine imaging. Somatostatin receptor scintigraphy with Pentetreotide is effective in visualizing neuroendocrine tumors, and its metastasis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 138661-02-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P2022.
Penthiopyrad
Penthiopyrad (MTF-753) is a carboxamide Fungicide. Penthiopyrad inhibits SDH. Penthiopyrad exhibits broad-spectrum antifungal activity, being effective not only against Basidiomycetes, but also against Ascomycetes and Deuteromycetes. Penthiopyrad inhibits the mycelial growth of Alternaria mali, Botrytis cinerea, Monilinia mali, Rhizoctonia solani and Sclerotinia sclerotiorum on PDA medium, with EC50 values ranging from <0.4 ppm to 0.34 ppm and MIC values ranging from 6.6 ppm to 47.9 ppm[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTF-753. CAS No. 183675-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17520.
Pentixafor
Pentixafor is a peptide that targets CXCR4. Pentixafor is capable of being labelled with 68Gallium (68Ga) for positron emission tomography (PET) imaging[1][2][3][4]. Pentixafor can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. CAS No. 1341207-62-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153549.
Pentosan Polysulfate Sodium (W/W 43%)
Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIV agent. Pentosan Polysulfate Sodium is used for the treatment of interstitial cystitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 140207-93-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0203A.
Pentostatin
Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 pM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI-825; Deoxycoformycin. CAS No. 53910-25-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-A0006.
Pentoxifylline
Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BL-191; PTX; Oxpentifylline. CAS No. 6493-5-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-B0715.
Pentynoic acid STP ester sodium
Pentynoic acid STP ester sodium is a click chemistry reagent containing a terminal propargyl group and a STP ester group. Pentynoic acid STP ester sodium is suitable for protein modification[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1807530-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138246.
Peonidin 3-arabinoside
Peonidin 3-arabinoside is an anthocyanin found in vaccinium mytrillus. Peonidin 3-arabinoside binds to the ALK5 and has anticancer activity. Peonidin 3-arabinoside also has antioxidant, anti-inflammatory, and anti-urinary tract infection properties[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 27214-74-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12973.
Peonidin-3-O-galactoside chloride
Peonidin-3-O-galactoside chloride is an anthocyanin with antioxidant properties and blood-brain barrier permeability. Peonidin-3-O-galactoside chloride inhibits pancreatic lipase, with an IC50 value of 23.2 μg/mL against porcine pancreatic lipase. Peonidin-3-O-galactoside chloride mediates neuroprotection, regulates glucose metabolism, protects cells from high glucose-induced damage, promotes glucose uptake and increases ATP production. Peonidin-3-O-galactoside (chloride) can be used in the research of obesity and neurodegenerative diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 28148-89-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126411.
Peonidin 3-O-glucoside chloride
Peonidin 3-O-glucoside chloride is an agonist of the free fatty acid receptor FFAR1 and Glucokinase. Peonidin 3-O-glucoside chloride enhances insulin secretion of pancreatic beta cells and increases glucose uptake by liver cells. Peonidin 3-O-glucoside chloride activates FFAR1, promotes the phosphorylation of related proteins in the insulin secretion pathway, and increases the expression of FFAR1. In liver cells, Peonidin 3-O-glucoside chloride activates GK and regulates proteins associated with carbohydrate metabolism. Peonidin 3-O-glucoside chloride can be used in diabetes research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6906-39-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W040127.
Pep19-2.5
Pep19-2.5 is an synthetic and antitoxin peptide, blocks the intracellular endotoxin signaling cascade. Pep19-2.5 inhibits signaling of lipopeptides (LP) and lipopolysaccharides (LPS) mediated by transmembrane and cytosolic pattern recognition receptors (PRRs). The signaling cascades lead to inflammation and cell pyroptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1322711-38-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3496.
Pep-1 (uncapped)
Pep-1 (uncapped) is a specific ligand of IL-13Ra2. Pep-1 (uncapped) exerts cell penetrating activity through receptor-mediated endocytosis, can cross the blood-tumor barrier (BTB) and target glioma cells. Pep-1 (uncapped) can enhance the uptake of nanoparticles by tumor cells and enhance the cell penetration ability of nanoparticles, and can be used to develop targeted drug delivery systems for glioma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 395069-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1848.
Pep-20
Pep-20 is a CD47/SIRPα blocking peptide with KD values of 2.91 and 3.63 μM for human and mouse CD47, respectively. IC50 values for blocking the human and mouse CD47/SIRPα interaction are 24.56 and 12.03 μM, respectively. Pep-20 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3056822-31-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P11097.
Pep2-8
Pep2-8 is a PCSK9 inhibitor with a binding KD of 0.7 μM and an IC50 of 1.4 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1541011-97-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2276.
Pepinemab
Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: VX 15/2503. CAS No. 2097151-87-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99407.
Pepsin
Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin contributes to proteolysis of food proteins in the vertebrate stomach[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.4.23.1. CAS No. 9001-75-6. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-P1635.
Pepsin (MS Grade)
Pepsin (MS Grade) is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin (MS Grade) contributes to proteolysis of food proteins in the vertebrate stomach[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.4.23.1 (MS Grade). CAS No. 9001-75-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-E70198.
Pepstatin
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pepstatin A. CAS No. 26305-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0018.
Peptide5
Peptide5, a connexin 43 mimetic peptide, reduce animals swelling, astrogliosis, and neuronal cell death after spinal cord injury[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 916977-43-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2275.
Peptide P60
Peptide P60 is a FOXP3 inhibitor. Peptide P60 reduces the nuclear translocation of FOXP3 and impairs FOXP3-mediated inhibition of NF-κB and NFAT activity. Peptide P60 inhibits the immunosuppressive activity of regulatory T cells and restores the proliferation and activation of effector T cells. Peptide P60 induces lymphoproliferative autoimmune syndrome in neonatal ICR mice and reduces the number of CD4+CD25+Foxp3+ T cells in the spleen. Peptide P60 enhances the efficacy of AH1 (HY-P4193) peptide vaccine and recombinant adenovirus-based HCV NS3 vaccine in BALB/c mice, including protective effects against CT26 tumor implantation. Peptide P60 can be used in studies related to tumor immunity, viral infection and lymphoproliferative autoimmune syndrome[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FOXP3 inhibitor P60. CAS No. 1319725-20-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1684.
Peptide YY (PYY) (3-36), Human is an endogenous appetite suppressing peptide. Peptide YY (PYY) (3-36), Human, a neuropeptide Y (NPY) Y2 receptor agonist, is a powerful inhibitor of intestinal secretion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123583-37-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10000.
Peptide YY (PYY), human
Peptide YY (PYY) is a gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (PYY) can mediate its effects through the Neuropeptide Y receptors. Uses: Scientific research. Category: Signaling pathways. CAS No. 118997-30-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1514.
Peptone from soya
Peptone from soy (peptones, soybean) is a peptone. Peptone from soy provides nitrogen and carbon sources, as well as other nutrients. Peptone from soy can stimulate/regulate the biosynthesis of cyclic eicosanoids. Peptone from soy induces dose-dependent contraction of guinea pig lung parenchyma. Peptone from soy can be used in microbial and cell culture[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Peptones, soybean. CAS No. 91079-46-8. Pack Sizes: 25 g; 100 g; 500 g; 1 k g. Product ID: HY-W133891.
Peramivir
Peramivir is an novel cyclopentane neuraminidase inhibitor of influenza virus. Peramivir has antiviral activity and anti-cytokines stom effects. Peramivir can be used for the research of COVID-19[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RWJ-270201; BCX-1812. CAS No. 330600-85-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17015A.
Peramivir trihydrate (Standard)
Peramivir (trihydrate) (Standard) is the analytical standard of Peramivir (trihydrate). This product is intended for research and analytical applications. Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RWJ 270201 trihydrate (Standard); BCX 1812 trihydrate (Standard). CAS No. 1041434-82-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17015R.
Perenostobart
Perenostobart (SRF617) is a human IgG4 antibody with inhibitory activity against CD39 ATPase. Perenostobart inhibits CD39-mediated hydrolysis of extracellular ATP to AMP, with IC50 values of 1.9 nM (HEK293 OE cells), 0.7 nM (MOLP-8 cells), and 1.2 nM (RBC-lysed whole blood). Perenostobart enhances CD4+ T-cell proliferation, promotes dendritic cell maturation, and boosts inflammasome activation in macrophages in the presence of ATP. Perenostobart demonstrates significant single-agent anti-tumor efficacy in MOLP-8 and H520 xenograft models. Perenostobart can be used for the study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SRF617. CAS No. 2643331-31-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990068.
Peresolimab
Peresolimab is a humanized IgG1-κ antibody targeting to PD-1. Peresolimab potentially stimulates physiological immune inhibitory pathways to restore immune homeostasis. Peresolimab can be used in research of rheumatoid arthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY-3462817. CAS No. 2411580-63-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9993.
Perfluoro(2-methyl-3-oxahexanoic) acid
Perfluoro (2-methyl-3-oxahexanoic) acid (HFPO-DA) is an orally active PPARα agonist with an EC50 of 2.1 μM for human PPARα. Perfluoro (2-methyl-3-oxahexanoic) acid induces peroxisome proliferation and increases the levels of proinflammatory mediators. It impairs intestinal barrier function and disrupts cecal flora balance. Perfluoro (2-methyl-3-oxahexanoic) acid is applicable to research related to developmental toxicity, hepatotoxicity and intestinal toxicity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HFPO-DA. CAS No. 13252-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W081067.
Perfluorobutanesulfonamide
Perfluorobutanesulfonamide (FBSA) is a per- and polyfluoroalkyl substance, which can be found as contaminant in wastewater[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FBSA. CAS No. 30334-69-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W674169.
Perfluorodecalin
Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood[3]. Perfluorodecalin enhances bone regeneration and cell viability[4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PP 5; Perfluorodecahydronaphthalene. CAS No. 306-94-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-108298.
Perfluorohexyloctane
Perfluorohexyloctane (NOV03), a semifluorinated alkane, reduces tear film instability in Meibomian gland dysfunction and evaporative dry eye disease. Perfluorohexyloctane is a long-term tamponade agent. Perfluorohexyloctane increases tear film breakup time and lipid layer thickness[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NOV03; SHR8058. CAS No. 133331-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W143531.
Perforin-IN-2
Perforin-IN-2 (Compound 1) is the inhibitor for perforin that inhibits perforin-mediated cell lysis, thereby reducing graft rejection during allogeneic bone marrow/stem cell transplantation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1567836-70-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-160214.
Pergolide mesylate
Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pergolide methanesulfonate; LY127809. CAS No. 66104-23-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13720A.
Perhexiline
Perhexiline is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline can be used in the research of cancers, and cardiovascular disease like angina[1][2][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6621-47-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-B1334.
Perhexiline maleate
Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline maleate induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline maleate can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline maleate can be used in the research of cancers, and cardiovascular disease like angina[1][2][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6724-53-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B1334A.
Pericyazine
Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis[1]. Pericyazine is a selective D2-dopamine receptor antagonist[2][3]. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Propericiazine; RP 8909. CAS No. 2622-26-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14263.
Perifosine
Perifosine is an oral Akt inhibitor which inhibits proliferation of different tumor cell lines with IC50s of 0.6-8.9 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KRX-0401; NSC 639966; D21266. CAS No. 157716-52-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50909.
(±)-Perillaldehyde
(±)-Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±)-Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2111-75-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W753791.
Perillartine
Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Perillartine. CAS No. 30950-27-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-N2084.
Perillene
Perillene is a component of the essential oil, has antibacterial and antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 539-52-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0827.
Perindopril
Perindopril erbumine is an angiotensin-converting enzyme inhibitor. Perindopril erbumine modulates NFκB and STAT3 signaling and inhibits glial activation and neuroinflammation. Perindopril erbumine can be used for the research of Chronic Kidney Disease and high blood pressure[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-9490. CAS No. 82834-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-B0130.
Perindoprilat-d4
Perindoprilat-d4 is the deuterium labeled Perindoprilat[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1356841-18-3. Pack Sizes: 1 mg. Product ID: HY-142578S.
Perindopril erbumine
Perindopril erbumine is an angiotensin-converting enzyme inhibitor. Perindopril erbumine modulates NF-κB and STAT3 signaling and inhibits glial activation and neuroinflammation. Perindopril erbumine can be used for the research of Chronic Kidney Disease and high blood pressure[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Perindopril (tert-butylamine salt); S-9490 erbumine. CAS No. 107133-36-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-B0130A.
PERK/eIF2α activator 1
PERK/eIF2α activator 1 (compound V8) is a flavonoid with an anti-tumor activity. PERK/eIF2α activator 1 induces apoptosis and activates the PERK-eIF2α-ATF4 pathway. PERK/eIF2α activator 1 inhibits HepG2 cell proliferation with an IC50 value of 23 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1178583-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158196.
PERK-IN-2
PERK-IN-2 is a potent PERK inhibitor with an IC50 of 0.2 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1337531-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135220.
PERK-IN-4
PERK-IN-4 is a potent and selective PERK (protein kinase R (PKR)-like endoplasmic reticulum kinase) inhibitor with an IC 50 of 0.3 nM. PERK is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1337531-89-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137813.
Permethrin
Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes)[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NRDC-143. CAS No. 52645-53-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B0887.
Permethrin-d5
Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NRDC-143-d5. CAS No. 1794760-19-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0887S.
Perospirone
Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM-9018 free base. CAS No. 150915-41-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0731A.
Peroxidase, Horseradish
Peroxidase, Horseradish actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-99-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-125859.
Peroxyfluor 1
Peroxyfluor 1 is a cell-permeable probe for H2O2. Peroxyfluor 1 represents a first-generation, green-fluorescent probe[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 817170-66-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1458.
Peroxynitrite sodium
Peroxynitrite sodium is a product of the diffusion-controlled reaction between nitric oxide and superoxide radicals, as well as an oxidant and an antiviral agent. Peroxynitrite sodium inhibits Mitochondrial respiration. Peroxynitrite sodium suppresses the replication of Coxsackievirus, partly by inhibiting viral RNA entry into host cells. Peroxynitrite sodium induces a significant nociceptive response[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14042-01-4. Pack Sizes: 3.17 mg (37.3 mM * 1 mL in Sodium hydroxide). Product ID: HY-155386.
Peroxy Orange 1
Peroxy Orange 1 (PO1) is a new H2O2 specific probe that can bind to green fluorescent highly reactive oxygen species (hROS) probe APF. Peroxy Orange 1 is also a living cell dye[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PO1. CAS No. 1199576-10-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103469.
Perphenazine
Perphenazine is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine also binds to Alpha-1A adrenergic receptor. Perphenazine inhibits cancer cell proliferation, and induces apoptosis. Perphenazine can be used in the research of mental disease, cancer, inflammation[1][3][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58-39-9. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-A0077.
Persicogenin
Persicogenin, isolated from Rhus retinorrhoea, possesses anti-cancer activity[1]. Uses: Scientific research. Category: Natural products. CAS No. 28590-40-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7636.
Pertuzumab
Pertuzumab, a humanized IgG1 monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer. Uses: Scientific research. Category: Signaling pathways. CAS No. 380610-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9912.
Pertuzumab (anti-HER2)
Pertuzumab (anti-HER2), a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer. Uses: Scientific research. Category: Signaling pathways. CAS No. 380610-27-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9912A.