MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Phosphatidylcholines, egg | Phosphatidylcholines, egg are a type of phosphatidylcholine that can be isolated and extracted from eggs, primarily present in egg yolks. As a major phospholipid component of cell membranes, Phosphatidylcholines, egg play a key role in providing nutrition and protection to the body. Phosphatidylcholines, egg can inhibit oxidative stress and neurotoxicity, exerting neuroprotective effects. Additionally, Phosphatidylcholines, egg can suppress the lymphatic absorption of cholesterol in the intestine and are also used in research on intestinal lipid absorption[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 97281-44-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125854. |  |
| Phosphatidylcholines,soya | Phosphatidylcholines,soya is a phosphatidylcholine from soybean used in the preparation of liposomes. Phosphatidylcholines,soya can be used as a vehicle in animal agent administration[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Soybean phosphatidylcholine. CAS No. 97281-47-5. Pack Sizes: 250 mg; 500 mg. Product ID: HY-125853. | |
| Phosphatidylglycerols (egg) sodium salt | Phosphatidylglycerols (PG) is a selective inhibitor targeting the TLR4 accessory protein CD14/MD-2 complex, inhibiting LPS or virus (such as RSV)-mediated inflammatory signaling pathways through competitive binding. Phosphatidylglycerols directly bind to viral particles to block infection, inhibit COX-2 expression to reduce the release of inflammatory factors (IL-6, IL-8), and improve oxidative stress by regulating mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols can be taken orally or by inhalation and can be used in the study of chronic inflammatory diseases (such as atherosclerosis) and respiratory viral infections (such as RSV)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Egg PG. CAS No. 383907-64-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W251428. | |
| Phosphatidylinositols, soya, sodium salts | Phosphatidylinositols, soya, sodium salts is a mixture of phosphatidylinositols. Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They act by recruiting and/or activating effector proteins and thus are involved in regulating various cellular functions, such as vesicular budding, membrane fusion and cytoskeleton dynamics[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 383907-36-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139533. | |
| Phosphatidylserine | Phosphatidylserine (Phospholipids) is a well-conserved anti-inflammatory and immunosuppressive signal. Phosphatidylserine is involved in membrane translocation and the activation of protein kinase C, participating in Akt signaling through its interaction with PIP3. The local exposure of Phosphatidylserine can interact with complement and other proteins, promoting microglial phagocytosis during critical periods of synaptic refinement. Phosphatidylserine can promote blood coagulation in the extracellular environment and acts as a "eat me" signal to clear out apoptotic cells. Phosphatidylserine can suppress inflammation in tissues by inducing TGF-β secretion and inhibiting immune responses[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phospholipids, phosphatidylserines; Serine glycerophosphatides. CAS No. 1446756-47-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0183. | |
| Phosphocholine chloride disodium | Phosphocholine Chloride Sodium Salt is an organic compound containing phosphate, choline and chloride ions. It is commonly used to prepare cell membranes and liposomes for drug delivery systems. Phosphocholine Chloride Sodium Salt has various applications in the pharmaceutical industry, especially as a stabilizer and surfactant. In addition, it is used as an emulsifier and conditioning agent in the manufacture of cosmetic and personal care products. Uses: Scientific research. Category: Signaling pathways. CAS No. 16904-96-4. Pack Sizes: 10 mM * 1 mL in Water; 250 mg; 500 mg; 1 g. Product ID: HY-W127640. | |
| Phosphocreatine | Phosphocreatine (creatine phosphate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway.[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Creatine phosphate; Creatinephosphoric acid. CAS No. 67-07-2. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0885. | |
| Phosphocreatine disodium | Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway.[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Disodium creatine phosphate. CAS No. 922-32-7. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-D0885B. | |
| Phosphodiesterase I | Phosphodiesterase I (PDE) is an enzyme that can catalyze the hydrolysis of the 3' ring phosphate bond of cyclic nucleotides, and is often used in biochemical research. Phosphodiesterase I acts as an important regulator of signal transduction mediated by the second messenger molecules cAMP and cGMP. According to their specificity to cyclic nucleotides, they can also be divided into different types, such as PDE1-PDE11, which also have certain potential in various diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PDE. CAS No. 9025-82-5. Pack Sizes: 100 U. Product ID: HY-P2878. | |
| Phosphoenolpyruvic acid potassium | Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phosphoenolpyruvate potassium. CAS No. 4265-07-0. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W008807. | |
| Phosphoglucomutase, Rabbit muscle | Phosphoglucomutase, Rabbit muscle is often used in biochemical studies. Phosphoglucomutase is an enzyme that can transfer the phosphate group on the α-D-glucose monomer forward from the 1-position to the 6-position or reversely transfer from the 6-position to the 1-position, and promote the glucose-1-phosphate and glucose-6-phosphate Transform each other. Phosphoglucomutase is a key enzyme in glycolysis and gluconeogenesis, and plays an important role in the metabolism of proteins, lipids and nucleic acids[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-81-4. Pack Sizes: 500 U; 1 KU. Product ID: HY-P2820. | |
| Phospholipase A2 | Phospholipase A2 (PLA2) is a calcium-dependent, heat-stable enzyme that catalyzes the hydrolysis of glycerophospholipids at the sn-2 position of cellular membranes, thereby releasing Arachidonic Acid (AA) (HY-109590). Phospholipase A2 is a key mediator in the biosynthesis of pro-inflammatory lipid mediators, critically involved in inflammatory processes. Phospholipase A2 can be used for cardiovascular and inflammatory diseases research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PLA2. CAS No. 9001-84-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3029. | |
| Phospholipase D, Streptomyces chromofuscus | Phospholipase D, Streptomyces chromofuscus (PLD) is an enzyme of the phospholipase superfamily, which widely exists in bacteria, yeast, plants, animals and viruses, and is often used in biochemical research. Phospholipase D can catalyze the hydrolysis of phosphodiester bonds in glycerophospholipids to produce phosphatidic acid and soluble choline. Phospholipase D is involved in a variety of disease-related processes, including diabetes, atherogenesis, obesity, tumorigenesis, immune response, and neuroendocrine function[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PLD. CAS No. 9001-87-0. Pack Sizes: 1 KU; 5 KU; 25 KU. Product ID: HY-P2812. | |
| Phosphoramide mustard cyclohexanamine | Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1566-15-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137316A. | |
| Phosphoramidon disodium | Phosphoramidon disodium, a microbial metabolite, is a specific metalloprotease thermolysin inhibitor with an IC50 of 0.4 μg/mL. Phosphoramidon disodium also inhibits endothelin-converting enzyme (ECE), neutral endopeptidase (NEP), and angiotensin-converting enzyme (ACE) with IC50 values of 3.5, 0.034, and 78 μM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 164204-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N2021A. | |
| Phosphoribosyl pyrophosphate pentasodium | Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRPP pentasodium. CAS No. 108321-05-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013046. | |
| Phosphorylase a, rabbit muscle | Phosphorylase a, rabbit muscle is glycogen phosphorylase isolated from rabbit muscle. Phosphorylase a, rabbit muscle catalyzes glycogenolysis, converting glycogen and inorganic phosphate into glucose-1-phosphate to supply energy for muscle contraction[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9032-10-4. Pack Sizes: 5 mg. Product ID: HY-P2734. | |
| Phosphorylcholine | Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Phosphocholine. CAS No. 3616-4-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B2233B. | |
| Phosphorylcholine chloride | Phosphorylcholine chloride (Phosphocholine chloride) is the main phospholipid component in eukaryotic biofilms. Phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phosphocholine chloride. CAS No. 107-73-3. Pack Sizes: 10 mM * 1 mL in Water; 500 mg. Product ID: HY-B2233. | |
| Phosphorylethanolamine | Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine. CAS No. 1071-23-4. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N5034. | |
| PhosTAC5 | PhosTAC5 is a phosphorylation targeting chimera (PhosTAC) molecule composed of a linker with fivePEG groups. PhosTAC5 induces dephosphorylation of PDCD4 and FOXO3a[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3064090-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148509. | |
| PhosTAC7 | PhosTAC7 is a heterobifunctional molecule named as a Phosphorylation Targeting Chimera (PhosTAC). PhosTAC7 can dephosphorylate the PDCD4 protein, FOXO3a protein, and tau protein by recruiting serine/threonine protein phosphatase 2A (PP2A). PhosTAC7 offers the advantage of selectively modulating the phosphorylation state of individual target proteins, making it a promising tool for research in cancer and tau protein-related neurodegenerative diseases (Alzheimer's disease)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OGTAC-3. CAS No. 3016307-75-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145232. | |
| Photoclick myristic acid | Photoclick myristic acid is a derivative of Myristic acid (HY-N2041) with an alkyne group and a photo-activatable diazirine group. Photoclick myristic acid can be used as a probe in protein research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2707485-30-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-W895359. | |
| Phox-I2 | Phox-I2 is a selective inhibitor of p67phox-Rac1 interaction, binds to p67phox with high affinity with a Kd of ~150 nM. Phox-I2 is a NADPH oxidase 2 (NOX2) inhibitor and inhibits reactive oxygen species (ROS) production[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 353495-22-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-119576. | |
| PHPS1 | PHPS1 is a potent and selective Shp2 inhibitor with Kis of 0.73, 5.8, 10.7, 5.8, and 0.47 μM for Shp2, Shp2-R362K, Shp1, PTP1B, and PTP1B-Q, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 314291-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112368. | |
| pH Receptor Probe | pH Receptor Probe is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 312961-83-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1563. | |
| PHT-7.3 | PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 μM). PHT-7.3 inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling. PHT-7.3 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1614225-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128590. | |
| Phthalaldehyde | Phthalaldehyde (Phthaldialdehyde) reacts with proteins containing primary amines and blocked amino-terminal peptides of amino acids. Phthalaldehyde stabilizes bacterial outer membranes and cell walls, increases the optical density of bacterial cell suspensions, and inhibits bacterial lysis induced by ethylenediaminetetraacetic acid and sodium dodecyl sulfate. Phthalaldehyde exhibits bactericidal activity against Gram-negative vegetative bacteria[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phthaldialdehyde. CAS No. 643-79-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g. Product ID: HY-W012669. | |
| Phthalaldehyde-d6 | Phthalaldehyde-d6 is the deuterium labeled Phthalaldehyde (HY-W012669). Phthalaldehyde is a biochemical assay reagent, which modifies the amino acid and measure the derivative through HPLC. Phthalaldehyde forms a fluorescent compound with α-amino group[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68234-47-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W738417. | |
| Phthalocyanine | Phthalocyanine is a photosensitizer. Phthalocyanine has a light-killing effect on bacterial biofilms, effectively inactivating bacteria. Phthalocyanine can be linked to anticancer drugs to target cancer. Phthalocyanine can also be used to develop chemical sensors for studying microbial infections and tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 574-93-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-121310. | |
| PHTPP | PHTPP is a selective estrogen receptor β (ERβ) antagonist with 36-fold selectivity over ERα[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 805239-56-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103456. | |
| p-Hydroxymandelic acid | p-Hydroxymandelic acid is a valuable aromatic fine chemical and widely used for production of pharmaceuticals and food additives. Uses: Scientific research. Category: Signaling pathways. CAS No. 1198-84-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-113027. | |
| Phyllanthin | Phyllanthin is an effective oral anticancer agent. Phyllanthin inhibits MOLT-4 cell viability, increases apoptosis, inhibits cell migration and invasion. Phyllanthin exerts anti-fibrotic effects by down-regulating TGF signaling pathway via ALK5 and Smad2/3. Phyllanthin also has anti-inflammatory and antibacterial properties [1] [2] [3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10351-88-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N4107. | |
| Physalin A | Physalin A is a biologically active withanolide. Physalin A shows anti-inflammatory, antifibrotic and ameliorative effects on autophagy in models of disc degeneration. Physalin A has antitumor activity and can induce apoptosis, ROS production and G2/M phase cell cycle arrest. Besides. Physalin A can significantly increase the activity of quinone reductase and increase the expression of detoxifying enzymesc[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23027-91-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9942. | |
| Physalin B | Physalin B, one of the major active steroidal constituents of Cape gooseberry, induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Physalin B inhibits the ubiquitin-proteasome pathway and induces incomplete autophagic response in human colon cancer cells in vitro[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23133-56-4. Pack Sizes: 1 mg. Product ID: HY-N7695. | |
| Physalin D | Physalin D is isolated from the aerial parts of Physalis angulate. Physalin D displays considerable cytotoxicity against several cancer cell lines, showing IC50 values in the range of d 0.28 to 2.43 microg/mL. Physalin D has the potential for the cancer disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 54980-22-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N9912. | |
| Physalin F | Physalin F is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 57423-71-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N7696. | |
| Physcion | Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Parietin; Rheochrysidin. CAS No. 521-61-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0108. | |
| Physcion 8-O-β-D-glucopyranoside | Physcion 8-O-β-D-glucopyranosideis an anthraquinone compound isolated from Rumex japonicus Houtt. Physcion 8-O-β-D-glucopyranoside exerts anti-inflammatory and anti-cancer properties, can be for common malignancy cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23451-01-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N5091. | |
| Physostigmine | Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eserine. CAS No. 57-47-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N6608. | |
| Physostigmine-d3 | Physostigmine-d3 is the deuterium labeled Physostigmine. Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eserine-d3. CAS No. 1217704-11-4. Pack Sizes: 1 mg. Product ID: HY-N6608S. | |
| Physostigmine salicylate | Physostigmine salicylate (Eserine salicylate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine salicylate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine salicylate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine salicylate is also an antidote for anticholinergic poisoning[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eserine salicylate. CAS No. 57-64-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1266. | |
| Phytanic acid-d3 | Phytanic acid-d3 is the deuterium labeled Phytanic acid[1]. Phytanic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Alpha Methylacyl CoA Racemase Deficiency, Rhizomelic Chondrodysplasia Punctata and Infantile Refsum Disease[2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1383920-40-8. Pack Sizes: 1 mg (31.65 mM * 100 μL in Ethanol); 5 mg (31.65 mM * 500 μL in Ethanol). Product ID: HY-113067S. | |
| Phytic acid (50% w/w in water) | Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound. Phytic acid can be derived from the seeds of legumes. Phytic acid is a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research[1][2][3][4][5][6][7][8][9][10]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Inositol hexaphosphate; SNF472 free acid. CAS No. 83-86-3. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-N0814. | |
| Phytic acid sodium salt | Phytic acid (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) sodium salt is an orally active compound. Phytic acid sodium salt can be derived from the seeds of legumes. Phytic acid sodium salt is a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid sodium salt attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid sodium salt can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research[1][2][3][4][5][6][7][8][9][10]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: myo-Inositol, hexakisdihydrogen phosphate sodium salt; Inositol hexaphosphate sodium salt. CAS No. 14306-25-3. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-N2581. | |
| Phytochelatin 2 (PC2) TFA | Phytochelatin 2 (PC2) TFA is a phytochelatin, an important heavy metal-binding peptide. Phytochelatin 2 (PC2) TFA can chelate metals, prevent metal toxicity, and maintain metal stability in the internal environment[1]. Uses: Scientific research. Category: Peptides. CAS No. 1426828-27-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2512A. | |
| Phytohemagglutinin | Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PHA-M. CAS No. 9008-97-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7038. | |
| Phytol | Phytol ((E)-Phytol) is an orally active diterpenoid alcohol that can be extracted from chlorophyll. Phytol has antioxidant, anti-inflammatory, anti-schistosomiasis and antibacterial activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)?-Phytol. CAS No. 150-86-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g. Product ID: HY-N3075. | |
| Phytolaccagenin | Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802-12-6. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N1433. | |
| Phytomonic acid | Phytomonic acid is a long-chain fatty acid containing a cyclopropane ring produced by Lactobacillus reuteri. Lactobacilli that normally produce Lactobacillic acid also have the ability to resist TNF-α[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 503-06-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-124003. | |
| Phytosphingosine | Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC50 value of 33.4 μM and can be used in the study of type II diabetes[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Hydroxysphinganine. CAS No. 554-62-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011303. | |
| Phytosterols | Phytosterols are anticancer agents. Phytosterols can be used in research related to cardiovascular disease and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 949109-75-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-122320. | |
| PI-103 | PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 nM. PI-103 induces autophagy[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 371935-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10115. | |
| PI-273 | PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 925069-34-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103489. | |
| PI3K/Akt/CREB activator 1 | PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2708177-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151527. | |
| PI3K/mTOR Inhibitor-13 sodium | PI3K/mTOR Inhibitor-13 sodium is an orally active dual inhibitor of phosphoinositol 3-kinase (PI3K) and mTOR kinase. PI3K/mTOR Inhibitor-13 sodium has potential applications in sexual diseases, solid tumor and idiopathic pulmonary fibrosis (IPF)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361009-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153120A. | |
| PI3K/mTOR Inhibitor-4 | PI3K/mTOR Inhibitor-4 is an orally active pan-class I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 has enzymatic inhibition activity for PI3Kα, PI3Kγ, PI3Kδ and mTOR with IC50 values of 0.63 nM, 22 nM, 9.2 nM and 13.85 nM, respectively. PI3K/mTOR Inhibitor-4 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361215-32-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128333. | |
| PI4Kβ/PKG-IN-2 | PI4Kβ/PKG-IN-2 (Compound 20) is an orally active dual inhibitor of Plasmodium phosphatidylinositol 4-kinase beta (PI4Kβ) and cGMP-dependent protein kinase (PKG). PI4Kβ/PKG-IN-2 has potent inhibitory effects on Plasmodium. PI4Kβ/PKG-IN-2 is promising for research of malaria[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3099010-20-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174134. | |
| PI4KIIIbeta-IN-10 | PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC50 of 3.6 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1881233-39-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100198. | |
| PI4KIIIbeta-IN-9 | PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1429624-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19798. | |
| PI4KIII beta inhibitor 3 | PI4KIII beta inhibitor 3 is a novel and high effective PI4KIIIβ inhibitor with IC50 of 5.7 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1245319-54-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 50 mg. Product ID: HY-15679. | |
| PI-55 | PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins induced haustorium formation and increased parasite aggressiveness[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1122579-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141519. | |
| Piboserod | Piboserod is an orally available selective antagonist of the 5-HT4 receptor, with a Ki value of approximately 0.1 nM for human 5-HT4 receptors. Piboserod can competitively bind to the 5-HT4 receptor and block the activation of the 5-HT4 receptor. Piboserod can inhibit the enhancing effect of 5-HT on the nerve-mediated contraction response of the human bladder detrusor muscle. Piboserod is mainly used in the research of urinary system diseases (such as overactive bladder) and cardiovascular diseases (such as chronic heart failure)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-207266. CAS No. 152811-62-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-15574. | |
| Pibrentasvir | Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-530. CAS No. 1353900-92-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101662. | |
| PIC1 PA | PIC1 PA, a 15 amino-acid peptide, is a potent PIC1 analog that inhibits classical pathway mediated complement activation. PIC1 PA functionally disrupts the C1s-C1r-C1r-C1s/MASPs interaction with collagen-like region (CLR) of C1q/MBL, respectively. PIC1 PA specifically binds to the CLR of C1q and bounds to purified C1q with a mean equilibrium dissociation constant (KD) of 33.3 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1356469-36-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10827. | |
| Picamilon | Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid. CAS No. 34562-97-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-107482. | |
| Picaridin | Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial, anticandidal and antifungal properties[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lcaridin. CAS No. 119515-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-116144. | |
| Picaridin (Standard) | Picaridin (Standard) is the analytical standard of Picaridin. This product is intended for research and analytical applications. Picaridin (Lcaridin) is a broad spectrum arthropod repellent. The repellent and deterrent activities of Picaridin involve olfactory sensing in mosquitoes, and ticks, via their interactions with odorant receptor proteins[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lcaridin (Standard). CAS No. 119515-38-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116144R. | |
| Piceatannol | Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI)[1]. Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties[2]. Piceatannol induces apoptosis in DLBCL cell lines[3]. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Astringenin; trans-Piceatannol. CAS No. 10083-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13518. | |
| Piceatannol (Standard) | Piceatannol (Standard) is the analytical standard of Piceatannol. This product is intended for research and analytical applications. Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI)[1]. Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties[2]. Piceatannol induces apoptosis in DLBCL cell lines[3]. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Astringenin (Standard); trans-Piceatannol (Standard). CAS No. 10083-24-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13518R. | |
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