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p-Nitrobenzyl mesylate
p-Nitrobenzyl mesylate (4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate) is a reagent used to alkylate phosphorothioates, forming phosphorothioate epitopes that can be recognized by specific antibodies. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate; PNBM. CAS No. 39628-94-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118380.
p-Nitrophenyl phosphorylcholine
p-Nitrophenyl phosphorylcholine (4-Nitrophenylphosphorylcholine) is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can be measured at 405 nm at pH 7.2-7.5. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Nitrophenylphosphorylcholine; 4-Nitrophenylphosphorylcholine; O-(4-Nitrophenylphosphoryl)choline. CAS No. 21064-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-100045.
p-nitro-Pifithrin-α
p-nitro-Pifithrin-α, a cell-permeable analog of pifithrin-α, is a potent p53 inhibitor. p-nitro-Pifithrin-α suppresses p53-mediated TGF-β1 expression in HK-2 cells. p-nitro-Pifithrin-α inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice fed a high-fat diet [4].non-alcoholic fatty liver disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 389850-21-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-130437.
PNR-3-80
PNR-3-80 is an endonuclease G (ENDOG) inhibitor with an IC50 of 0.67 μM. As a non-competitive binder to the ENDOG-substrate complex, PNR-3-80 specifically inhibits the endonuclease activity of ENDOG. PNR-3-80 reduces cell death induced by Cisplatin (HY-17394) and Docetaxel (HY-B0011), and inhibits DNA damage and autophagy (autophagy) induced by Etoposide (HY-13629). PNR-3-80 can be used in studies related to cell injury[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1424353-63-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176835.
PNR-7-02
PNR-7-02 is a dual Rev1 and human DNA polymerase η (hpol η) inhibitor, with an IC50 value of 8 μM against hpol η. PNR-7-02 binds to hpol η to disrupt the orientation of template DNA and block the catalytic function of hpol η. When used in combination with Cisplatin (HY-17394), PNR-7-02 induces DNA damage and replication stress in cells with intact hpol η function. PNR-7-02 can be used in mechanism studies related to chronic myeloid leukemia and ovarian cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1633660-76-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-117664.
PNT2001
PNT2001 (LY4181530) is a potent prostate specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. PNT2001 can improve cellular internalization. 177Lu- and 225Ac-labeled PNT2001 can be used in prostate cancer research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY4181530; PSMA-62. CAS No. 2790413-59-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P6825.
PNU-120596
PNU-120596 (NSC 216666) is a potent and selective α7 nAChR positive allosteric modulator (PMA) that can cross the blood-brain barrier, with an EC50 of 216 nM. PNU-120596 is inactive against α4β2, α3β4, and α9α10 nAChRs. PNU-120596 has the potential for psychiatric and neurological disorders research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 216666. CAS No. 501925-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12152.
PNU-142633
PNU-142633 is a high affinity, selective and orally active 5-HT1D receptor agonist with Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor and human 5-HT1B receptor, respectively. PNU-142633 has anti-migraine efficacy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 187665-65-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-103131.
PNU-159682
PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance. Uses: Scientific research. Category: Signaling pathways. CAS No. 202350-68-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16700.
PNU-282987
PNU-282987 is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 can be used for the research of central and peripheral nervous systems[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123464-89-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12560A.
PNU 37883 hydrochloride
PNU 37883 hydrochloride (PNU 37883A) is a selective vascular ATP-sensitive potassium (Kir6, KATP) channels blocker. PNU 37883 hydrochloride has diuretic effects with specific binding in kidney and vascular smooth muscle rather than in brain or pancreatic beta cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PNU 37883A. CAS No. 57568-80-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108589.
PNU-74654
PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell. Uses: Scientific research. Category: Signaling pathways. CAS No. 113906-27-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-101130.
Pobilukast
Pobilukast is a classical CysLT1 receptor antagonist. Pobilukast can be used for the research of asthma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF-104353; SK&F-104353. CAS No. 107023-41-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106785.
Pocenbrodib
Pocenbrodib is a P300/CBP inhibitor. Pocenbrodib blocks the function of P300/CBP and inhibits the acetylation of histones and non-histone proteins. Pocenbrodib may be used in research related to castration-resistant prostate cancer and other cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2304372-79-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141546.
Pociredir
Pociredir (FTX-6058) is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). Pociredir can induce HbF protein expression in cell and murine models. Pociredir can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FTX-6058. CAS No. 2490676-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139400.
Podofilox
Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Podophyllotoxin. CAS No. 518-28-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-15552.
POLA1 inhibitor 1
POLA1 inhibitor 1 (Compound 12) is an orally active POLA1 inhibitor. POLA1 inhibitor 1 shows antitumor activity against several tumor histotypes and Adarotene-resistant cell line[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2217671-41-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147812.
Polatuzumab
Polatuzumab is a monoclonal antibody that targets CD79b on the surface of B cells. Polatuzumab can be used to synthesize the ADC Polatuzumab Vedotin (HY-132253), which has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2279068-37-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99042.
Polatuzumab vedotin
Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin has the potential for the research of Large B-cell lymphomas (LBCL)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1313206-42-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132253.
Polatuzumab vedotin (solution)
Polatuzumab vedotin solution is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin solution has the potential for the research of Large B-cell lymphomas (LBCL)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1313206-42-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132253A.
Polidocanol,Hydroxyl Value 40-60 mgKOH/g
Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Polyoxyethylene lauryl ether; Polyoxyethyleneglycol Dodecyl Ether. CAS No. 9002-92-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B2106.
Poloxamer 124 (L44)
Poloxamer 124 L44 is a block polymer of polyoxyethylene and polyoxypropylene and a hydrophobic surfactant. Poloxamer 124 L44 causes eye irritation and exhibits oral toxicity in albino rats with an LD50 of 5 g/kg. Poloxamer 124 L44 has reversible adverse effects on triglyceride and cholesterol transport in the lymphatic system of rats. Poloxamer 124 L44 can form thermoreversible hydrogels and is used as a food additive and as a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG-PPG-PEG, 2200 (Average). CAS No. 9003-11-6. Pack Sizes: 50 g; 100 g; 250 g. Product ID: HY-D1005A6.
Poloxamer 188
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models. Poloxamer 188 can be used for drug delivery[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG-PPG-PEG, 8800 (Average Mn). CAS No. 9003-11-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D1005A.
Poloxamer 188 (F68)
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG-PPG-PEG, 8400(Average Mn). CAS No. 9003-11-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-D1005H.
Poloxamer 338 (F108)
Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG-PPG-PEG, 14600 (Average). CAS No. 9003-11-6. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-D1005A22.
Poloxamer 401 (L121)
Poloxamer 401 L121 is a block copolymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 4400. Poloxamer has the ability to inhibit P-gp. Poloxamer 401 inhibits multiagent resistance and adjuvant activity. Poloxamer 401 can be used as a cosmetic ingredient. Poloxamer 401 can be used in nanoparticle engineering (lymphatic targeting particles) research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG-PPG-PEG, 4400 (Average). CAS No. 9003-11-6. Pack Sizes: 25 mL; 50 mL. Product ID: HY-D1005A23.
Poloxamer 407 (F127)
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8 AM and Quest Rhod-4 AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG-PPG-PEG, 12600 (Average Mn). CAS No. 9003-11-6. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-D1005.
Poloxin
Poloxin is a non-ATP competitive Polo-like Kinase 1 (PLK1) inhibitor that targets the polo-box domain, with an IC50 of appr 4.8 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 321688-88-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12134.
PolQi1
PolQi1 is a selective inhibitor targeting the Polθ domain of DNA polymerase. PolQi1 inhibits the Polθ-mediated microhomology end joining (TMEJ/alt-EJ) pathway, reducing insertion/deletion (Indels) and imprecise editing events during DNA repair. PolQi1 can enhance the efficiency and accuracy of homology-directed repair (HDR) or Prime editing, and reduce off-target effects; and in combination with DNA-PK inhibitor AZD-7648 (HY-111783), exert efficient genome editing capabilities with dual pathway regulation. PolQi1 can be mainly used in gene editing research (such as CRISPR-Cas9 or Prime editing system optimization) to improve the precision editing efficiency of difficult-to-edit cells (such as primary hepatocytes and mouse embryos)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2607139-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159078.
PolQi2
PolQi2 is a PolΘ inhibitor that targets and inhibits alt-EJ (alternative end-joining) repair by inhibiting the helicase domain at the N-terminus of PolΘ. PolQi2 enhances the precision and integration efficiency of gene editing at different loci and in various cell lines. Furthermore, the combined use of PolQi2 with DNA-PK inhibitors reduces the off-target effects of Cas9. PolQi2 can be used in gene editing research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2565638-16-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150279.
Polθ/PARP-IN-1
Polθ/PARP-IN-1 (compound 25d) is a potent dual DNA polymerase theta (Polθ) and PARP inhibitor with IC50 values of 45.6, 5.4 nM, respectively. Polθ/PARP-IN-1 shows antiproliferative activity. Polθ/PARP-IN-1 induces apoptosis and cell cycle arrest at G2/M phase, causes DNA damage. Polθ/PARP-IN-1 shows anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3056709-95-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161302.
Poly(2-hydroxyethyl methacrylate) (Mv 20000)
Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25249-16-5. Pack Sizes: 100 mg. Product ID: HY-112531.
Poly(2-hydroxyethyl methacrylate) (Mv 300000)
Poly(2-hydroxyethyl methacrylate) (Mv 300000) is a biocompatible, optically transparent, hydrophilic, and non-degradable polymer with excellent cytocompatibility, eliciting a minimal immunological response from host tissue. Poly(2-hydroxyethyl methacrylate) (Mv 300000) can be used for different biomedical applications, such as bone tissue regeneration, wound dressings and drug delivery[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25249-16-5. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-112531B.
Polyacrylamide,average Mn 150000
Polyacrylamide, average Mn 150000 (PAM, average Mn 150000) is a versatile, high-molecular-weight polyacrylamide copolymer. Polyacrylamide series materials can maintain enzyme activity in enzyme immobilization, act as drug carriers to achieve controlled release, serve as smart materials responding to temperature/pH stimuli, and be used for in vitro toxin adsorption and soft tissue filling through mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAM,average Mn 150000. CAS No. 9003-5-8. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W115727E.
Poly(acrylic acid) (MW 100000) (35% in water)
Poly(acrylic acid) (MW 100000) (35% in water) is a polyacrylic acid with a molecular weight of 100000 (an anionic polymer), which can be used as a corrosion inhibitor and surface stabilizer. Poly(acrylic acid) (MW 100000) can be used for biomedical applications, such as drug delivery[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-1-4. Pack Sizes: 5 mL; 10 mL; 50 mL. Product ID: HY-W243303M.
Poly(acrylic acid) (MW 2000)
Poly(acrylic acid) (MW 2000) is a polyacrylic acid with a molecular weight of 2000. Poly(acrylic acid) (MW 2000) is an anionic polymer. Poly(acrylic acid) (MW 2000) can be as a corrosion-mitigating and surface-stabilizing agent. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-1-4. Pack Sizes: 1 g; 5 g. Product ID: HY-W243303A.
Poly(acrylic acid) (MW 450000)
Poly(acrylic acid) (MW 450000) is a polyacrylic acid with a molecular weight of 450000. Poly(acrylic acid) (MW 450000) is an anionic polymer. Poly(acrylic acid) (MW 450000) can be as a corrosion-mitigating and surface-stabilizing agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-1-4. Pack Sizes: 5 g; 10 g. Product ID: HY-W243303E.
Polyadenylic acid potassium
Polyadenylic acid potassium, also known as Poly(A), is enzymatically added to messenger RNA (mRNA) in eukaryotic cells to stabilize mRNAs. Poly(A) is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly(A) is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids. Small molecules that could bind to this poly(A) tail could influence and possibly inhibit mRNA function and subsequent protein production in the cell leading to the development of new type of therapeutic agents. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Poly(A). CAS No. 26763-19-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W416291.
Polyamidoamine (20% in methanol)
Polyamidoamine (PAMAM) (20% in methanol) is a new type of drug carrier that has drug encapsulation capabilities internally and biocompatibility on the surface, and can be used as a drug delivery system. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAMAM. CAS No. 153891-46-4. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-164657.
Polyaniline
Polyaniline can be used to make antibacterial agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25233-30-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W017767.
Polycaprolactone
Polycaprolactone is a biodegradable polyester commonly used in various biomedical and industrial applications. It is a white waxy polymer that can be molded into various shapes and forms. Polycaprolactone has various properties suitable for these applications, including low melting point, high flexibility and slow biodegradation rate. It can be used as a raw material for the production of tissue engineering scaffolds, drug delivery systems, and medical implants. In addition, it is used as a binder in the production of adhesives, coatings and paints. Uses: Scientific research. Category: Signaling pathways. CAS No. 24980-41-4. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W250312.
Polycarbophil
Polycarbophil is an orally active hydrophilic polymer. Polycarbophil achieves bioadhesion through hydrogen bonding between carboxyl groups and mucosal surfaces, and prolongs compound retention time and regulates compound release through swelling properties. Polycarbophil relieves constipation and diarrhea[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-97-8. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-154659.
Polydatin
Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Piceid. CAS No. 27208-80-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0120A.
Polydatin (Standard)
Polydatin (Standard) is the analytical standard of Polydatin. This product is intended for research and analytical applications. Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Piceid (Standard). CAS No. 27208-80-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0120AR.
Poly(D,L-lactide-co-glycolide)
Poly(D,L-lactide-co-glycolide) is a biodegradable polymer copolymer. Poly(D,L-lactide-co-glycolide) undergoes degradation through ester bond hydrolysis into lactic acid and glycolic acid. These two products can be naturally eliminated through metabolism in the body (such as the tricarboxylic acid cycle), without the risk of long-term accumulation. Poly(D,L-lactide-co-glycolide) can be used in medical sutures, implants, and drug delivery systems[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26780-50-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W723152.
Poly-D-lysine hydrobromide (MW 30000-70000)
Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PDLHB (MW 30000-70000). CAS No. 27964-99-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139201.
Poly-D-lysine hydrobromide (MW 4000-15000)
Poly-D-lysine hydrobromide (MW 4000-15000) (PDLHB (MW 4000-15000)) is an artificially synthesized polymer matrix widely used in neuronal cell culture. Poly-D-lysine hydrobromide is also known as a calcium-sensing receptor (CaSR) agonist peptide[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PDLHB (MW 4000-15000). CAS No. 27964-99-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-139201D.
Poly-D-lysine hydrobromide (MW 70000-150000)
Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PDLHB (MW 70000-150000). CAS No. 27964-99-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139201A.
Poly(ethylene glycol) diacrylate (MW 1000)
Poly(ethylene glycol) diacrylate (PEGDA) (MW 1000) is a versatile polymer material that is widely used as a building material for hydrogel scaffolds, especially in the fields of tissue engineering and regenerative medicine[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEGDA (MW 1000). CAS No. 26570-48-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W110542D.
Poly(ethylene glycol) diacrylate (MW 20000)
Poly(ethylene glycol) diacrylate (MW 20000) (PEGDA (MW 20000)) is a derivative of polyethylene glycol. Poly(ethylene glycol) diacrylate (MW 20000) can be used in the formation of a cross-linked polymers[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEGDA (MW 20000). CAS No. 26570-48-9. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W110542M.
Poly(ethylene glycol) diacrylate (MW 250),MEHQ as inhibitor
Poly(ethylene glycol) diacrylate (PEGDA) (MW 250), MEHQ as inhibitor is a versatile polymer material that is widely used as a building material for hydrogel scaffolds, especially in the fields of tissue engineering and regenerative medicine. Poly(ethylene glycol) diacrylate (MW 250), MEHQ as inhibitor can be used to construct optical cross-linked hydrogel implants[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEGDA (MW 250),MEHQ as inhibitor. CAS No. 26570-48-9. Pack Sizes: 1 g; 5 g; 10 g; 50 g. Product ID: HY-W110542N.
Poly(ethylene glycol) diacrylate (MW 4000), MEHQ as inhibitor
Poly(ethylene glycol) diacrylate (PEGDA) (MW 4000), MEHQ as inhibitor is a versatile polymer material that is widely used as a building material for hydrogel scaffolds, especially in the fields of tissue engineering and regenerative medicine. Poly(ethylene glycol) diacrylate (MW 4000), MEHQ as inhibitor can be used to construct enzyme-responsive hydrogel drug delivery system[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEGDA (MW 4000), MEHQ as inhibitor. CAS No. 26570-48-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W110542P.
Poly(ethylene glycol) diacrylate (MW 6000)
Poly(ethylene glycol) diacrylate (PEGDA) (MW 6000) is a versatile polymer material that is widely used as a building material for hydrogel scaffolds, especially in the fields of tissue engineering and regenerative medicine. Poly(ethylene glycol) diacrylate (MW 6000) can be used as a building material for wound dressing hydrogels[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEGDA (MW 6000). CAS No. 26570-48-9. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-W110542G.
Poly(ethylene glycol) diglycidyl ether (MW 500)
Poly(ethylene glycol) diglycidyl ether (MW 500) is a nonlinear analogue of polyethylene glycol (PEG) and can be used as a cross-linking agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26403-72-5. Pack Sizes: 25 mL; 50 mL; 100 mL. Product ID: HY-W763546A.
Poly(ethylene glycol) dimethacrylate (MW 2000)
Poly(ethylene glycol) dimethacrylate (MW 2000) is a nonlinear analogue of polyethylene glycol (PEG) and can be used as a cross-linking agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25852-47-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W110540D.
Poly(ethylene glycol) dithiol (Mn 1000)
Poly(ethylene glycol) dithiol (Mn 1000) is a thiol-modified PEG that can be used to synthesize dithiol-terminated amphiphilic diblock copolymers for drug delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68865-60-1. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-139480A.
Poly(ethylene glycol) dithiol (Mn 3400)
Poly(ethylene glycol) dithiol (Mn 3400) is a polymer and can be used as a biomaterial to prepare hydrogels[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68865-60-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-139480.
Polyethylenimine (branched) (30% in water)
Polyethylenimine (branched) (30% in water) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (30% in water) can ensnare DNA as well as attach to cell membrane. Polyethylenimine (branched) (30% in water) also retains a substantial buffering capacity at virtually any pH. Polyethylenimine (branched) (30% in water) is widely used as transfection reagent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9002-98-6. Pack Sizes: 1 mL; 5 mL; 10 mL. Product ID: HY-W250110.
Polyethylenimine (branched) (MW 10000)
Polyethylenimine (branched) (MW 10000) (PEI (branched) (MW 10000)) is a cationic polymer widely used as a nonviral nucleotide delivery reagent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEI (branched) (MW 10000). CAS No. 9002-98-6. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W250110I.
Polyethylenimine (branched) (MW 25000)
Polyethylenimine (branched) is a commonly used non-viral DNA transfection reagent. Polyethylenimine (branched) (MW 25000) binds to plasmid DNA[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEI (branched) (MW 25000). CAS No. 9002-98-6. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W250110E.
Polygalacic acid
Polygalacic acid, is a triterpene, isolated from the root of Polygala tenuifolia Willd. Polygalacic acid inhibits MMP expression. Polygalacic acid may have a therapeutic effect in Osteoarthritis (OA) treatment [1]. Polygalacic acid exerts a significant neuroprotective effect on cognitive impairment, PA improves cholinergic system reactivity by inhibiting acetylcholinesterase (AChE) activity, increasing choline acetyltransferase (ChAT) activity, and elevating levels of acetylcholine (Ach) in the hippocampus and frontal cortex[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22338-71-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0801.
Polygalasaponin XXXI
Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Onjisaponin F. CAS No. 79103-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2216.
Polyglutamine binding peptide 1
Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). Polyglutamine binding peptide 1 inhibits polyQ protein aggregation in vitro and suppresses polyQ-induced cell death in cell culture[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 274914-75-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-P10818.
Polyglycerol-polyricinoleate
Polyglycerol-polyricinoleate (PGPR) is an emulsifier commonly used in the food industry. Polyglycerol-polyricinoleate can improve food texture and stability[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PGPR. CAS No. 29894-35-7. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-29350.
Polygodial
Polygodial (Poligodial) is an antifungal potentiator[1]. Polygodial is a sesquiterpene with anti-hyperalgesic properties[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Poligodial; Tadeonal. CAS No. 6754-20-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108450.
Poly(hexamethylenebiguanide) hydrochloride
Poly(hexamethylenebiguanide) hydrochloride (PHMB) is an antimicrobial and antiviral agent. Poly(hexamethylenebiguanide) hydrochloride is active against both Gram-positive and Gram-negative bacteria. Poly(hexamethylenebiguanide) hydrochloride works by adsorbing to the surface of cellulose, which can damage microbial cell membranes and interfere with metabolism. Poly(hexamethylenebiguanide) hydrochloride is widely used in medical, clothing and household textiles, and cosmetic fields[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PHMB. CAS No. 32289-58-0. Pack Sizes: 10 g; 25 g; 50 g. Product ID: HY-W017766.
Polyinosinic-polycytidylic acid
Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid can directly trigger cancer cells to undergo apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Poly(I:C). CAS No. 24939-03-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107202.
Polyinosinic-polycytidylic acid sodium
Polyinosinic-polycytidylic acid (Poly(I:C)) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Poly(I:C) sodium. CAS No. 42424-50-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135748.
Poly-L-γ-glutamic acid sodium
Poly-L-γ-glutamic acid sodium is a macromolecular polymer formed by the linkage of glutamic acid residues via peptide bonds between γ-amino and carboxyl groups. Poly-L-γ-glutamic acid sodium plays an important role as a carrier material in compound delivery systems. Poly-L-γ-glutamic acid sodium can deliver Paclitaxel (HY-B0015) to colon cancer cells, reduce cell viability and inhibit the growth of colon cancer spheroids. Poly-L-γ-glutamic acid sodium can be used as a carrier material and in studies related to colon cancer in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 208106-41-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149449.
Poly-L-Glutamic acid (MW 700000)
Poly-L-Glutamic acid (MW 700000) is a compound carrier. Poly-L-Glutamic acid (MW 700000) can be used for the targeted delivery of anticancer compounds[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25513-46-6. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-112111.