MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Poly-L-glutamic acid sodium salt (MW 15000) | Poly-L-glutamic acid sodium salt (MW 15000) is a kind of biochemical reagent. Uses: Scientific research. Category: Signaling pathways. CAS No. 26247-79-0. Pack Sizes: 10 mg; 25 mg. Product ID: HY-W596474C. |  |
| Poly-L-glutamic acid sodium salt (MW 30000) | Poly-L-glutamic acid sodium salt (MW 30000) is a kind of biochemical reagent. Uses: Scientific research. Category: Signaling pathways. CAS No. 26247-79-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W596474D. | |
| Poly-L-lysine hydrobromide (MW 150000-300000) | Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25988-63-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126437C. | |
| Poly-L-lysine hydrobromide (MW ?300000) | Poly-L-lysine hydrobromide (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine hydrobromide (MW 150000-300000) has good biocompatibility. Poly-L-lysine hydrobromide (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25988-63-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126437D. | |
| Poly-L-lysine hydrobromide (MW 30000-70000) | Poly-L-lysine hydrobromide (MW 30000-70000) is a water-soluble synthetic polypeptide. Poly-L-lysine hydrobromide (MW 30000-70000) downregulates Bcl-2 and upregulates Bax and p53 proteins. Poly-L-lysine hydrobromide (MW 30000-70000) promotes Apoptosis and reduces VEGF expression. Poly-L-lysine hydrobromide (MW 30000-70000) shows anticancer activity against a variety of tumors. Poly-L-lysine hydrobromide (MW 30000-70000) can also be used as a coating material[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25988-63-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126437. | |
| Poly-L-lysine hydrobromide (MW 70000-150000) | Poly-L-lysine (hydrobromide) (MW 70000-150000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 70000-150000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 70000-150000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25988-63-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126437B. | |
| Poly-L-lysine hydrochloride | Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26124-78-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126437A. | |
| Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) | Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) has good biocompatibility. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PLL solution 0.01%, sterile-filtered, hydrobromide, MW 150000-300000, for cell culture. CAS No. 25988-63-0. Pack Sizes: 10 mL; 50 mL. Product ID: HY-126437J. | |
| Poly-L-ornithine hydrobromide (MW 30000-70000) | Poly-L-ornithine hydrobromide (MW 30000-70000) is a poly-lysine derivative with a molecular weight of 30000-70000. Poly-L-ornithine hydrobromide (MW 30000-70000) binds to the surface of cell culture vessels through positively charged amino acid residues to form a coating that promotes cell adhesion and provides cells with a matrix environment required for growth. Poly-L-ornithine hydrobromide (MW 30000-70000) is used as a coating agent in cell culture and can be used for the study of primary culture of neurons (such as dopaminergic neurons and oligodendrocytes)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Ornithine homopolymer hydrobromide (MW 30000-70000). CAS No. 27378-49-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126436A. | |
| Polymyxin B | Polymyxin B is an antibiotic. Polymyxin B inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B neutralizes the effect of endotoxin. Polymyxin B induces bacterial death by increasing its permeability. Polymyxin B is used in endotoxemia research[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1404-26-8. Pack Sizes: 100 mg; 500 mg. Product ID: HY-149179. | |
| Polymyxin B1 | Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4135-11-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-A0248A. | |
| Polymyxin B nonapeptide | Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 86408-36-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-106783. | |
| Polymyxin B nonapeptide TFA | Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2220175-42-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106783A. | |
| Polymyxin B Sulfate | Polymyxin B Sulfate is an antibiotic. Polymyxin B Sulfate inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B Sulfate neutralizes the effect of endotoxin. Polymyxin B Sulfate induces bacterial death by increasing its permeability. Polymyxin B Sulfate is used in endotoxemia research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1405-20-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-A0248. | |
| Polyoxyl 100 stearate | Polyoxyl 100 stearate (PEG-100 stearate) is a non-ionic surfactant formed by polyethylene glycol (PEG) and stearic acid, and it is commonly used in pharmaceutical preparations, nanocarriers, emulsification systems and cosmetic formulations[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG 100 stearate. CAS No. 9004-99-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-101530C. | |
| Polyoxyl 20 Cetostearyl Ether | Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68439-49-6. Pack Sizes: 5 g; 10 g. Product ID: HY-154639. | |
| Polyphyllin I | Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 50773-41-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0047. | |
| Polypodine B | Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of Acanthamoeba castellani. Polypodine B has moderate antifungal activity. Polypodine B can be used for research on parasitic diseases and fungal infections[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5β-Hydroxyecdysterone. CAS No. 18069-14-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-129671. | |
| Polyquaternium-1 | Polyquaternium-1 (Polidronium chloride; PQ-1) is an antimicrobial preservative and an activator of NF-κB. Polyquaternium-1 targets bacterial cell membranes, commonly used in ophthalmic surgery. Polyquaternium-1 adsorbs to the surface of microbial membranes through its polycationic properties, destroying membrane integrity and inducing potassium ion leakage, leading to bacterial death. Polyquaternium-1 exerts antimicrobial effects at a concentration of 0.001% and has low toxicity to mammalian cells. Polyquaternium-1 can be used to prepare products such as glaucoma eye drops (Travoprost preparations containing PQ-1), artificial tears, and contact lens solutions to reduce the ocular surface toxicity of traditional preservatives such as benzalkonium chloride (HY-B2232)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Polidronium chloride. CAS No. 75345-27-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127032. | |
| Polysodium 4-styrenesulfonate (MW 70000) | Poly(sodium 4-styrenesulfonate) (MW 70000) is an ion exchange exchange polyelectrolyte[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25704-18-1. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W739372A. | |
| Polystyrene sulfonic acid (30% in water) | Polystyrene sulfonic acid (30% in water) is a potentially toxic hazardous substance. Polystyrene-derived microplastics (PS-MPs) are harmful to zebrafish hearts and induce male reproductive toxicity in mice. MCE offers Polystyrene products in solution packaging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 28210-41-5. Pack Sizes: 50 g; 100 g; 500 g. Product ID: HY-148163. | |
| Polysucrose 70 | Polysucrose 70 is a branched polysaccharide polymer with a high molecular weight. Polysucrose 70 is formed by the copolymerization of sucrose and epichlorohydrin, which can be used for cell separation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26873-85-8. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-131960A. | |
| Poly(U) potassium | Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Polyuridylic acid potassium. CAS No. 28086-43-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-131920A. | |
| Poly(vinyl alcohol-co-ethylene) ethylene 32 mol % | Poly(vinyl alcohol-co-ethylene) ethylene 32 mol % is a non-toxic polymer with good hydrophilicity and biocompatibility. Poly(vinyl alcohol-co-ethylene) ethylene 32 mol % has high tensile strength and excellent film-forming property. Poly(vinyl alcohol-co-ethylene) ethylene 32 mol % can be used in research related to packaging materials[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25067-34-9. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-185567. | |
| Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) | Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 130000-23000 and hydrolytic properties. Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate and polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVA (Mw 13000-23000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 87-89% hydrolyzed). CAS No. 9002-89-5. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0850J. | |
| Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed) | Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed) is a non-biodegradable, hydrophilic, odorless biomedical polymer with cell adhesion/proliferation inhibition, peripheral nerve regeneration induction, dissolution enhancement, and non-toxic, biocompatible properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9002-89-5. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0850. | |
| Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) | Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVA (Mw 30000-70000, 87-90% hydrolyzed); Poly(Ethenol) (Mw 30000-70000, 87-90% hydrolyzed). CAS No. 9002-89-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-Y0850E. | |
| Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed) | Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed), also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVA (Mw 31000-50000, 98-99% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 98-99% hydrolyzed). CAS No. 9002-89-5. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-Y0850K. | |
| Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) | Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) can be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics, and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVA (Mw 9000-10000, 80% hydrolyzed); Poly(Ethenol) (Mw 9000-10000, 80% hydrolyzed). CAS No. 9002-89-5. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-Y0850I. | |
| Polyvinylpyrrolidone, average Mw~40000 | Polyvinylpyrrolidone, average Mw~40000 is a multifunctional synthetic polymer with an average molecular weight of 40,000 Da. Polyvinylpyrrolidone, average Mw~40000 is widely used to synthesize nanoparticles. Polyvinylpyrrolidone, average Mw~40000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVP, average Mw~40000; Polyvidone, average Mw~40000; Povidone, average Mw~40000. CAS No. 9003-39-8. Pack Sizes: 25 g. Product ID: HY-B1620L. | |
| Polyvinylpyrrolidone K17 | Polyvinylpyrrolidone K17 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K17 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVP K17; Polyvidone K17; Povidone K17. CAS No. 9003-39-8. Pack Sizes: 100 g; 500 g; 1 k g. Product ID: HY-B1620C. | |
| Polyvinylpyrrolidone K30 | Polyvinylpyrrolidone K30 is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVP K30; Polyvidone K30; Povidone K30. CAS No. 9003-39-8. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-B1620. | |
| Polyvinylpyrrolidone K60 | Polyvinylpyrrolidone K60 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K60 promotes amorphous dispersion and inhibits crystallization of the drug[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVP K60; Polyvidone K60; Povidone K60. CAS No. 9003-39-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B1620E. | |
| Polyvinylpyrrolidone K90 | Polyvinylpyrrolidone K90 can be used to prepare drug delivery systems, such as electrospun nanofibrous membranes. Polyvinylpyrrolidone K90 is widely used in human and veterinary medicine as an effective wound healing promoter and disinfectant when combined with iodine and other compounds. In addition, Polyvinylpyrrolidone K90 is also used to stabilize nanosuspensions, interact with the surface of drug crystals, and remain bound to the surface after drying[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PVP K90; Polyvidone K90; Povidone K90. CAS No. 9003-39-8. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B1620H. | |
| Polzastobart | Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JTX 8064. CAS No. 2640981-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990061. | |
| Pomaglumetad methionil hydrochloride | Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) is an orally active, methionine prodrug of the selective mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil hydrochloride has the potential for schizophrenia research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY2140023 hydrochloride. CAS No. 635318-26-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105040C. | |
| Pomalidomide | Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-4047. CAS No. 19171-19-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-10984. | |
| Pomalidomide 4'-PEG2-azide | Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Pomalidomide 4'-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2271036-45-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-132208. | |
| Pomalidomide 4'-PEG3-azide | Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1?degrader based on Rucaparib by using the PROTAC approach[1]. Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2271036-46-3. Pack Sizes: 100 mg; 250 mg. Product ID: HY-130652. | |
| Pomalidomide 5'-pip-acid | Pomalidomide 5'-pip-acid is an E3 ligase ligand-linker conjugate derived from the molecular glue Pomalidomide (HY-10984), which can be used to synthesize the dual-target PROTAC degrader PROTAC CBP/p300/BRD4 Degrader-1 (HY-181758) targeting CBP/p300 and BRD4. Pomalidomide 5'-pip-acid shows anti-proliferative activity against cancer cells with an IC50 of 2.73 nM. Pomalidomide 5'-pip-acid induces anti-proliferative effects in cancer cells. Pomalidomide 5'-pip-acid is applicable to research related to prostate cancer and colorectal cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2467965-70-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W877997. | |
| Pomalidomide-6-OH | Pomalidomide-6-OH is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-OH can be connected to the ligand for protein by a linker to form PROTAC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1547162-44-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139540. | |
| Pomalidomide-amido-C3-COOH | Pomalidomide-amido-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. Uses: Scientific research. Category: Signaling pathways. CAS No. 2162120-77-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-131185. | |
| Pomalidomide-amido-C5-PEG2-C6-chlorine | Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivant of Pomalidomide (HY-10984)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1835705-69-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137905. | |
| Pomalidomide-C3-adavosertib | Pomalidomide-C3-adavosertib is a rapid and selective PROTAC Wee1 degrader (IC50=3.58 nM). Pomalidomide-C3-adavosertib shows anti-cancer cell proliferation activity, and induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414418-49-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-133618. | |
| Pomalidomide-C3-NH2 hydrochloride | Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2154342-45-5. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-131888. | |
| Pomalidomide-C3-NHS ester | Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. Uses: Scientific research. Category: Signaling pathways. CAS No. 2828476-87-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148142. | |
| Pomalidomide-C4-NH2 hydrochloride | Pomalidomide-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2162120-73-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138845A. | |
| Pomalidomide-cyclohexane | Pomalidomide-cyclohexane is an E3 ligase ligand-linker conjugate. Uses: Scientific research. Category: Signaling pathways. CAS No. 2924858-40-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163928. | |
| Pomalidomide-PEG1-C2-COOH | Pomalidomide-PEG1-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2139348-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 1 g. Product ID: HY-137531. | |
| Pomalidomide-PEG1-C2-N3 | Pomalidomide-PEG1-C2-N3 (Cereblon Ligand-Linker Conjugates 13) is a cereblon E3 ligand-linker conjugate that can be used to synthesisi selective CDK6 PROTAC degrader CP-10 (HY-125835). Pomalidomide-PEG1-C2-N3 can be used for the research of cancers[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 50. CAS No. 2271036-44-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-125843. | |
| Pomalidomide-PEG2-azide | Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. Pomalidomide-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2267306-14-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-137537. | |
| Pomalidomide-PEG2-COOH | Pomalidomide-PEG2-COOH (Pomalidomide 4'-PEG2-acid) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pomalidomide 4'-PEG2-acid. CAS No. 2140807-17-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-131872. | |
| Pomalidomide-PEG3-C2-NH2 hydrochloride | Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride. CAS No. 2446474-09-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-128716B. | |
| Pomalidomide-PEG4-azide | Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Pomalidomide-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2271036-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-141015. | |
| Pomalidomide-PEG4-C2-NH2 hydrochloride | Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 2357105-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-112599B. | |
| Pomalidomide-PEG6-butyl iodide | Pomalidomide-PEG6-butyl iodide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1835705-74-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg. Product ID: HY-136156. | |
| Pomalidomide (Standard) | Pomalidomide (Standard) is the analytical standard of Pomalidomide. This product is intended for research and analytical applications. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-4047 (Standard). CAS No. 19171-19-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10984R. | |
| POMHEX | POMHEX, a racemic mixture and a cell-permeable pivaloyloxymethyl (POM) proagent of HEX, is a potent, ENO2-specific inhibitor of enolase. POMHEX exhibits low-nanomolar potency against ENO1-deleted cells in vitro and is capable of eradicating ENO1-deleted xenografted tumours in vivo. POMHEX is a potent glycolysis inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2004714-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131904. | |
| Pomiferin | Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC50 of 1.05 μM, and also potently inhibits mTOR (IC50, 6.2 μM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 5113. CAS No. 572-03-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4315. | |
| Pomolic acid | Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from?Euscaphis japonica?(Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC)[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Randialic acid A. CAS No. 13849-91-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6601. | |
| Ponatinib | Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AP24534. CAS No. 943319-70-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12047. | |
| Ponatinib hydrochloride | Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AP24534 hydrochloride. CAS No. 1114544-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108766. | |
| Ponceau 4R | Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acid Red 18; New Coccine. CAS No. 2611-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0193. | |
| Ponceau S, BS | Both Ponceau S and Ponceau BS are synthetic dyes commonly used in biological research. They are commonly used as protein stains to visualize proteins in western blots and other protein detection analyses. Ponceau S is a red dye, while Ponceau BS is a blue shade of the same dye. Both dyes bind to positively charged amino acid residues in proteins for easy visualization. However, Ponceau S is more commonly used due to its higher sensitivity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acid Red 112, BS. CAS No. 6226-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-12489A. | |
| Poncirin | Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freunds Adjuvant (CFA)-induced inflammatory pain models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14941-08-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N2258. | |
| Ponesimod | Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACT-128800. CAS No. 854107-55-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10569. | |
| Ponezumab | Ponezumab (PF-04360365; RN 1219) is a humanized anti-amyloid-β (Amyloid-β) IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves the performance of mice in various learning and memory models. Ponezumab is applicable to the research of Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-04360365; RN 1219. CAS No. 1178862-65-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99216. | |
| Ponicidin | Ponicidin (Rubescensine B) is an orally active RIPK1 inhibitor with a Kd value of 135 nM. Ponicidin inhibits the JAK2/STAT3 pathway to induce apoptosis, activates the PI3K/Akt pathway, upregulates SIRT1 expression, alleviates oxidative stress, suppresses inflammatory responses and necroptosis, and blocks cell cycle progression. Ponicidin induces ROS production to exert antiproliferative and antiviral effects, while also improving cognitive function and reducing Aβ plaque deposition. Ponicidin can be used in studies related to hepatocellular carcinoma, Alzheimer's disease, and gastric cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Rubescensine B. CAS No. 52617-37-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N1535. | |
| Ponometrep | Ponometrep (BHV-2100) is a transient receptor potential melastatin 3 (TRPM3) antagonist with IC50 values of 1-10 nM. Ponometrep shows analgesic activity and can be used for the research of neurological diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BHV-2100. CAS No. 2776175-74-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-182466. | |
| Ponsegromab | Ponsegromab is a Growth differentiation factor 15 (GDF15) inhibitor with human, cynomolgus monkey, and mouse target IC50 values of 0.123 nM, 0.053 nM, and 0.102 nM, respectively[1][2]. Ponsegromab acts as a chemosensitizer, increases intracellular reactive oxygen species, reduces glutathione levels[1][2]. Ponsegromab can be used for the research of oxaliplatin-resistant colorectal cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF 06946860. CAS No. 2368950-15-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99241. | |
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