MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| 1,2-DLPC | 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-Dilauroyl-sn-glycero-3-phosphocholine. CAS No. 18194-25-7. Pack Sizes: 10 mM * 1 mL in Ethanol; 25 mg; 50 mg; 100 mg. Product ID: HY-107737. |  |
| 12-HETE | 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway[1].12-HETE has both anti-thrombotic and pro-thrombotic effects[2]. 12-HETE is a neuromodulator[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71030-37-0. Pack Sizes: 50 μg (312.04 μM * 0.5 mL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-113439. | |
| 1,2-Hexadecanediol | 1,2-Hexadecanediol is a reducing agent. 1,2-Hexadecanediol facilitates the decomposition of the metal-organic precursor, forms an intermediate Co2+Fe3+-oleate complex[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6920-24-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W011816. | |
| 12-Hydroxyjasmonic acid | 12-Hydroxyjasmonic acid is a metabolite of Jasmonic acid (HY-122464A) and an inducer of defense responses. 12-Hydroxyjasmonic acid can be isolated from potato leaflets. During the response of sugar beet plants to Cercospora beticola infection, 12-Hydroxyjasmonic acid is released through deglycosylation of its glucoside form and participates in the Jasmonic acid-mediated defense signaling pathway. 12-Hydroxyjasmonic acid mediates changes in source-sink relationships during pathogen infection, prioritizing the activation of defense processes over growth processes. 12-Hydroxyjasmonic acid serves as a substrate for salicylic acid Glycosyltransferases in tobacco and rice. 12-Hydroxyjasmonic acid can induce leaflet closure in Samanea saman. 12-Hydroxyjasmonic acid acts as a potato tuber-inducing substance. 12-Hydroxyjasmonic acid does not induce protoplast shrinkage in extensor motor cells of Samanea saman. 12-Hydroxyjasmonic acid can be used in studies related to brown spot disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 140631-27-2. Pack Sizes: 1 mg. Product ID: HY-N1033. | |
| 12-Hydroxynevirapine | 12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP) is a major oxidative metabolite of Nevirapine (HY-10570). Nevirapine is a non-nucleoside reverse transcriptase inhibitor indicated for the HIV-1 infections. Nevirapine causes idiosyncratic hepatotoxicity and mild-to-severe skin rashes. 12-Hydroxynevirapine, a non-reactive metabolite, can be bioactivated by sulphotransferases (SULTs) in the liver and skin, yielding the reactive species 12-Sulphoxy-nevirapine[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 12-hydroxy-NVP; 12-OH-NVP. CAS No. 133627-24-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148642. | |
| 12-Ketochenodeoxycholic acid | 12-Ketochenodeoxycholic acid is an anomalous bile acid and Chenodeoxycholic acid (HY-76847) precursor. 12-Ketochenodeoxycholic acid can be used for the research of hepatobiliary diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2458-8-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W403933. | |
| 12-Ketodeoxycholic acid | 12-Ketodeoxycholic acid (12-Ketolithocholic acid) is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 12-Ketolithocholic acid. CAS No. 5130-29-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-135772. | |
| 12-Oxo-9(Z)-dodecenoic acid | 12-Oxo-9(Z)-dodecenoic acid is an ester product. Uses: Scientific research. Category: Signaling pathways. CAS No. 60485-39-4. Pack Sizes: 1 mg (47.11 mM * 100 μL in Acetonitrile). Product ID: HY-165854. | |
| (±)-1,2-Propanediol | (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-(RS)-Propanediol; 1,2-Propylene glycol; Propylene glycol. CAS No. 57-55-6. Pack Sizes: 100 mL; 10 mM * 1 mL in DMSO; 500 mL; 1000 mL. Product ID: HY-Y0921. | |
| (±)-1,2-Propanediol-d6 | (±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-(RS)-Propanediol-d6; 1,2-Propylene glycol-d6; Propylene glycol-d6. CAS No. 52910-80-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0921S2. | |
| (±)-1,2-Propanediol-d8 | (±)-1,2-Propanediol-d8 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-(RS)-Propanediol-d8; 1,2-Propylene glycol-d8; Propylene glycol-d8. CAS No. 80156-55-4. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-Y0921S. | |
| 13,14-Dihydro-15-keto-PGE2 | 13,14-Dihydro-15-keto-PGE2 participates in Bifidobacterium animalis F1-7 to alleviate opioid-induced constipation by 5-HT pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 363-23-5. Pack Sizes: 1 mg (28.37 mM * 100 μL in Methyl acetate). Product ID: HY-113254. | |
| 13,14-Dihydro-15-keto prostaglandin D2 | 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DK-PGD2; 15-Oxo-13,14-dihydro-PGD2; 13,14-Dihydro-15-keto-PGD2. CAS No. 59894-07-4. Pack Sizes: 1 mg (28.37 mM * 100 μL in Methyl acetate); 5 mg (28.37 mM * 500 μL in Methyl acetate). Product ID: HY-118830. | |
| 1,3,6,8-Tetrakis[p-benzoic acid]pyrene | 1,3,6,8-Tetrakis[p-benzoic acid]pyrene (4,4',4'',4'''-(Pyrene-1,3,6,8-tetrayl)tetrabenzoic acid) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4,4',4'',4'''-(Pyrene-1,3,6,8-tetrayl)tetrabenzoic acid. CAS No. 933047-52-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W074644. | |
| 1,3,6-Tri-O-galloyl-beta-D-glucose | 1,3,6-Tri-O-galloyl-beta-D-glucose is a non-covalent inhibitor of tyrosinase (TYR), which can block the rate-limiting step of melanin synthesis and inhibit melanin deposition. 1,3,6-Tri-O-galloyl-beta-D-glucose has antioxidant and anti-inflammatory activities and can be used as a natural active ingredient to develop anti-freckle and whitening skin care products[1]. Uses: Scientific research. Category: Natural products. Alternative Names: 1,3,6-Tri-O-galloyl-β-D-glucose. CAS No. 18483-17-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N6006. | |
| 1,3-Dicaffeoylquinic acid | 1,3-Dicaffeoylquinic acid is a caffeoylquinic acid derivative that exhibits antioxidant activity and radical scavenging activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,3-O-Dicaffeoylquinic acid; 1,5-Dicaffeoylquinic acid. CAS No. 19870-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N1412. | |
| 1,3-Dicyclohexylurea (Standard) | 1,3-Dicyclohexylurea (Standard) is the analytical standard of 1,3-Dicyclohexylurea. This product is intended for research and analytical applications. 1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2387-23-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013989R. | |
| 1,3-Dihydroxyacetone | 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dihydroxyacetone. CAS No. 96-26-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0335. | |
| 1,3-Dioleoyl-2-stearoyl glycerol | 1,3-Dioleoyl-2-stearoyl glycerol (1,3-Olein-2-stearin) is a compound mentioned in the study of triglyceride composition in bovine milk fat. It has been identified and quantified by various methods, and its proportion and type in bovine milk fat have been determined. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,3-Olein-2-stearin; TG(18:1/18:0/18:1). CAS No. 2410-29-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-165041. | |
| 1,3-Diphenylguanidine-d10 | 1,3-Diphenylguanidine-d10 is the deuterium labeled 1,3-Diphenylguanidine (HY-W014332). 1,3-diphenylguanidine is the primary and secondary accelerator in the vulcanization of rubber and is found in the rubber industry[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2468795-96-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W716965. | |
| 1,3-Diphenylisobenzofuran | 1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DPBF. CAS No. 5471-63-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W011664. | |
| 1,3-Distearin | 1,3-Distearin (1,3-Distearoyl glycerol) is an intermediate for synthesizing non-steroidal anti-inflammatory agents, and can be used in the synthesis of Ibuprofen (HY-78131), Naproxen (HY-15030), Diclofenac (HY-15036), and other non-steroidal anti-inflammatory agents[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,3-Distearoyl glycerol; Glyceryl 1,3-distearate; DG(18:0/0:0/18:0). CAS No. 504-40-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W702781. | |
| 13-Hydroxy-12-oxo-9(Z),15(Z)-octadecadienoic acid | 13-Hydroxy-12-oxo-9(Z),15(Z)-octadecadienoic acid is a fatty acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 70597-03-4. Pack Sizes: 100 μg (644.27 μM * 500 μL in Ethanol). Product ID: HY-N16226. | |
| 1400W Dihydrochloride | 1400W dihydrochloride is the dihydrochloride form of 1400W (HY-18730). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a Kd value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 214358-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18731. | |
| (±)14,15-Epoxyeicosatrienoic acid | (±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonic acid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)14(15)-EET. CAS No. 197508-62-6. Pack Sizes: 50 μg (312.04 μM * 500 μL in Ethanol). Product ID: HY-150084. | |
| 1,4-b-D-Xylopentaose | 1,4-b-D-Xylopentaose is a linear pentasaccharide composed of 5 β-D-xylose units linked via 1,4-glycosidic bonds, and serves as a specific substrate for barley α-L-arabinofuranosidase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 49694-20-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-N6839. | |
| [1,4-BIs(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate | [1,4-Bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate ([Rh(dppb)(COD)]BF4) serves as a rhodium-based catalyst that facilitates regioselective hydrogenation and enantioselective reductive amination reactions. Uses: Scientific research. Category: Signaling pathways. Alternative Names: [Rh(dppb)(COD)]BF4. CAS No. 79255-71-3. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W010685. | |
| 14-Deoxy-11,12-didehydroandrographolide | 14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 14-dehydro Andrographolide; AP10. CAS No. 42895-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1490. | |
| 14-Deoxy-17-hydroxyandrographolide | 14-Deoxy-17-hydroxyandrographolide is an ent-labdane diterpenoid compound isolated from the aerial parts of Andrographis paniculate[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 14-Deoxy-17β-hydroxyandrographolide. CAS No. 869384-82-7. Pack Sizes: 1 mg. Product ID: HY-N1488. | |
| 14-Deoxyandrographolide | 14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4176-97-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4323. | |
| 1,4-Dibromobenzene-d4 | 1,4-Dibromobenzene-d4 is a deuterium labeled 1,4-Dibromobenzene. 1,4-Dibromobenzene is used as a fumigant and as a chemical intermediate for pharmaceuticals. Inhalation exposure gives rise to dizziness and chokingwhereas contact with skin or eye produces inflammation and burning in humans[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Dibromobenzene-d4. CAS No. 4165-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-76025S. | |
| 1,4-Dicaffeoylquinic acid | 1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid compound that can be isolated from Xanthii fructus and an inhibitor of xanthine oxidase (IC50: 7.36 μM). 1,4-Dicaffeoylquinic acid has anti-inflammatory activity and can inhibit the production of TNF-α induced by LPS (HY-D1056)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,4-DCQA. CAS No. 1182-34-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0358. | |
| 1,4-DPCA | 1,4-DPCA, a potent prolyl-4-hydroxylase inhibitor, is a collagen hydroxylation inhibitor in human foreskin fibroblasts with an IC50 of 2.4 μM. 1,4-DPCA inhibits prolyl-4-hydroxylases α isoforms stabilizes HIF-1α protein. 1,4-DPCA also inhibits factor inhibiting HIF (FIH) with an IC50 of 60 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 331830-20-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121172. | |
| 14-epi-Andrographolide | 14-epi-andrographolide is a diterpene analog of Andrographolide (HY-N0191), which is an NF-κB inhibitor and antiviral agent[1][2][3]. Uses: Scientific research. Category: Natural products. Alternative Names: 14-Epiandrographolide. CAS No. 142037-79-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0191A. | |
| (±)14-HDHA | (±)14-HDHA is the isomer of 14(S)-HDHA (HY-130239). 14(S)-HDHA is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)14-HDoHE; 14-hydroxy Docosahexaenoic acid; (±)14-HDoHE. CAS No. 87042-40-8. Pack Sizes: 25 μg (290.28 μM * 250 μL in Ethanol). Product ID: HY-130239A. | |
| 14(S)-HDHA | 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 14(S)-HDoHE. CAS No. 119433-37-3. Pack Sizes: 25 μg (290.28 μM * 250 μL in Ethanol). Product ID: HY-130239. | |
| 15-Acetyl-deoxynivalenol | 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 88337-96-6. Pack Sizes: 1 mg. Product ID: HY-N6683. | |
| 1,5-Anhydrosorbitol | 1,5-Anhydrosorbitol is a short-term marker for glycemic control. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,5-Anhydro-D-glucitol. CAS No. 154-58-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113075. | |
| 15-Azido-pentadecanoic acid | 15-Azido-pentadecanoic acid is a click chemistry reagent containing an azide group. Azido Palmitic Acid can be used to identify and characterize post-translationally palmitylated proteins with using a simple and robust two-step labeling and detection technique[1]. 15-Azido-pentadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Azido Palmitic Acid. CAS No. 118162-46-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151656. | |
| 15-Deoxy-Δ-12,14-prostaglandin J2 | 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 μM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 15d-PGJ2; 15-Deoxy-Δ12,14-PGJ2. CAS No. 87893-55-8. Pack Sizes: 1 mg (3.16 mM * 1 mL in Methyl acetate). Product ID: HY-108568. | |
| 15-keto-Prostaglandin E2 | 15-keto-Prostaglandin E2 (15-keto-PGE2) is an endogenous PGE2 metabolite. 15-keto-Prostaglandin E2 inhibits STAT3 activation by binding to the Cys259 residue of STAT3. 15-keto-Prostaglandin E2 binds to and stabilizes EP2 and EP4 receptors. 15-keto-Prostaglandin E2 inhibits the growth and progression of breast cancer cells. 15-keto-Prostaglandin E2 activates PPAR-γ and promotes fungal growth. 15-keto-Prostaglandin E2 disrupts glomerular vascularization during zebrafish development and reduces the surface area of the glomerular filtration barrier[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 15-keto-PGE2. CAS No. 26441-05-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113205. | |
| 15-LOX-1 inhibitor 1 | 15-LOX-1 inhibitor 1 is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC50 value of 0.19 μM. 15-LOX-1 inhibitor 1 protects macrophages from lipopolysaccharide-induced cytotoxicity. 15-LOX-1 inhibitor 1 inhibits NO formation and lipid peroxidation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2349374-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138989. | |
| 15-PGDH-IN-1 | 15-PGDH-IN-1 is a potent and orally active 15-PGDH inhibitior. 15-PGDH-IN-1 has inhibition activity against recombinant human 15-PGDH with an IC50 value of 3 nM. 15-PGDH-IN-1 can be used for the research of tissue repair and regeneration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241676-74-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151807. | |
| 15(S)-HEPE | 15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA. CAS No. 86282-92-0. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol); 50 μg (314.02 μM * 500 μL in Ethanol). Product ID: HY-130675A. | |
| 15(S)-HPETE | 15(S)-HPETE is a precursor of 15(S)-HETE (HY-113336). 15(S)-HPETE is a product of Arachidonic acid (HY-109590) in the 15-lipoxygenase pathway. 15(S)-HPETE reduces Bcl-2, Akt, and phosphorylated Akt protein levels. 15(S)-HPETE induces Apoptosis. 15(S)-HPETE antagonizes the angiogenic effects of 15(S)-HETE. 15(S)-HPETE exhibits antitumor effects against chronic myeloid leukemia. 15(S)-HPETE can be used in adipose tissue explant studies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 70981-96-3. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-113438. | |
| 16:0 DAP | 16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96326-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-144022. | |
| 16,16-Dimethyl prostaglandin E2 | 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 16,16-dimethyl PGE2. CAS No. 39746-25-3. Pack Sizes: 5 mg (26.28 mM * 500 μL in Methyl acetate); 10 mg (26.28 mM * 1 mL in Methyl acetate); 25 mg (26.28 mM * 2.5 mL in Methyl acetate); 50 mg (26.28 mM * 5 mL in Methyl acetate); 100 mg (26.28 mM * 10 mL in Methyl acetate). Product ID: HY-106420. | |
| 16α-Hydroxyestrone | 16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 16αOHE. CAS No. 566-76-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113344. | |
| 1,6-Di-O-galloyl-β-D-glucose | 1,6-Di-O-galloyl-β-D-glucose is a compound found in the fruit of Phyllanthus emblica. 1,6-Di-O-galloyl-β-D-glucose has HIV-1 reverse transcriptase (RT) inhibitory activity with an IC50 value of 270 μM. The inhibitory mechanism of 1,6-Di-O-galloyl-β-D-glucose is competitive inhibition of the template primer and non-competitive inhibition of the substrate (dTTP). 1,6-Di-O-galloyl-β-D-glucose can be used in anti-HIV research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23363-08-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W719041. | |
| 1,6-Hexanediyl bismethanethiosulfonate | 1,6-Hexanediyl bismethanethiosulfonate is a biochemical reagent. Uses: Scientific research. Category: Signaling pathways. CAS No. 56-01-9. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-W743760. | |
| 17a-Hydroxypregnenolone-d3 | 17a-Hydroxypregnenolone-d3 (17-OHP5-d3) is the deuterium labeled 17a-Hydroxypregnenolone (HY-113263). 17a-Hydroxypregnenolone is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 17-OHP5-d3. CAS No. 105078-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113263S. | |
| 17α-Hydroxyprogesterone | 17α-Hydroxyprogesterone is a steroid hormone. 17α-Hydroxyprogesterone induces ovarian growth and yolk production in female crabs and increases blood pressure in sheep. 17α-Hydroxyprogesterone is mainly used in research related to crustacean reproduction and animal hypertension[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 17-Hydroxyprogesterone; 17-OHP. CAS No. 68-96-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-B0891. | |
| 17α-Hydroxyprogesterone-d8 | 17α-Hydroxyprogesterone-d8 is the deuterium labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 17-Hydroxyprogesterone-d8; 17-OHP-d8. CAS No. 850023-80-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0891S. | |
| 17α-Hydroxyprogesterone (Standard) | 17α-Hydroxyprogesterone (Standard) is the analytical standard of 17α-Hydroxyprogesterone. This product is intended for research and analytical applications. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 17-Hydroxyprogesterone(Standard); 17-OHP (Standard). CAS No. 68-96-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0891R. | |
| 17β-Estradiol-3-β-D-glucuronide-d3 | 17β-Estradiol-3-β-D-glucuronide-d3 is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1260231-06-8. Pack Sizes: 500 μg. Product ID: HY-132723S. | |
| 17β-HSD1-IN-1 | 17β-HSD1-IN-1 (Compound 1) is a highly selective 17β-HSD1 inhibitor with IC50s of 5.6 and 3155 nM for 17β-HSD1 and 17β-HSD2, respectively. 17β-HSD1-IN-1 can be used for the research of non-small cell lung cancer (NSCLC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2760791-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145433. | |
| 17-HDHA | 17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 90780-52-2. Pack Sizes: 25 μg (290.28 μM * 250 μL in Ethanol); 50 μg (290.28 μM * 500 μL in Ethanol); 100 μg (290.28 μM * 1 mL in Ethanol). Product ID: HY-113512. | |
| 17-ODYA | 17-ODYA is a CYP450 ω-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor (IC50<100 nM) of the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonic acid. 17-ODYA completely attenuates the isoproterenol (ISO)-induced apoptosis, and necrosis in cultured cardiomyocytes[1][2][3]. 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 34450-18-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-101016. | |
| 17-Phenyl-ω-trinor-PGE2 | 17-Phenyl-ω-trinor-PGE2 is a PGE2 (HY-101952) analog, which is an agonist for EP1 and EP3 receptor. 17-Phenyl-ω-trinor-PGE2 inhibits the PAF-induced aggregation of human platelet-rich plasma (PRP) and Cicaprost (HY-19583) induced Cyclic AMP (HY-B1511) production[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38315-43-4. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-128039. | |
| 17(S)-HpDHA | 17(S)-HpDHA is the main 15-Lipoxygenase (LOX) isoenzyme: h15-LOX-1 and h15-LOX-2 and docosahexaenoic acid (DHA). product. 17(S)-HpDHA negatively regulates epoxide synthesis via allosteric regulation. 17(S)-HpDHA also inhibits platelet aggregation with an EC50 of approximately 1 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123673-33-6. Pack Sizes: 25 μg (277.40 μM * 250 μL in Ethanol); 50 μg (277.40 μM * 500 μL in Ethanol). Product ID: HY-116124. | |
| 18:0,18:1 PS | 18:0,18:1 PS is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 124262-93-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148978A. | |
| 18:0,18:1 PS sodium | 18:0,18:1 PS sodium is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS sodium mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS sodium to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 321883-23-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148978. | |
| 18:0-18:2 PE | 18:0-18:2 PE is an important component of phosphatidylethanolamine (PE), involved in phospholipid metabolism and associated with diseases such as ovarian cancer. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE is mainly used in the field of food science to improve the flavor of aquatic products, as well as medical research on diseases related to phospholipid metabolism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine. CAS No. 7266-53-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-143203. | |
| 18:0 Coenzyme A triammonium | 18:0 Coenzyme A (triammonium) is a preferred substrate of stearoyl-CoA desaturases (SCDs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 799812-87-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-E70265. | |
| 18:0 mPEG2000 PE | 18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG2000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (2 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG2000 PE ammonium can be used for the research of nanoprobes and drug delivery[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DSPE-mPEG2000; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]. CAS No. 156543-00-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142978. | |
| 18:0 mPEG2000 PE ammonium | 18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DSPE-mPEG2000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium. CAS No. 474922-77-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144013. | |
| 18:0 mPEG2000 PE sodium | 18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium. CAS No. 247925-28-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-112760. | |
| 18:1 BMP (S,S) ammonium | 18:1 BMP (S,S) ammonium is a bis(monoacylglycero)phosphate (BMP). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 18:1 LBPA (S,S). CAS No. 1246303-12-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N16011. | |
| 18:1 Cardiolipin disodium | 18:1 Cardiolipin disodium is a virulence regulator with two phosphate groups and four acyl chains.18:1 Cardiolipin disodium can be used in the study of the regulation and mechanism of bacterial infection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 115404-77-8. Pack Sizes: 10 mM * 1 mL in Methanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160202. | |
| 18:1 DGS-NTA(Ni) | 18:1 DGS-NTA(Ni) is a nickel chelating lipid. 18:1 DGS-NTA(Ni) has high affinity for histidine-tags and can bind histidine tags of recombinant proteins. 18:1 DGS-NTA(Ni) can be used for preparation of liposomes and nanosize multilamellar vesicles (NMVs) which are used in protein and peptide binding studies and antigen delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 231615-77-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N15871. | |
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