MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| 2,4-Difluorophenylethynylcobalamin | 2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH)[1]. 2,4-Difluorophenylethynylcobalamin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: F2PhEtyCbl. CAS No. 2101750-19-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-154992. |  |
| 2,4-Di-tert-butylphenol (Standard) | 2,4-Di-tert-butylphenol (Standard) is the analytical standard of 2,4-Di-tert-butylphenol (HY-W014589). This product is intended for research and analytical applications. 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities, and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of pharmaceuticals and fragrances[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-DTBP (Standard). CAS No. 96-76-4. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-W014589R. | |
| 24-Hydroxycholesterol | 24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR. Uses: Scientific research. Category: Signaling pathways. CAS No. 30271-38-6. Pack Sizes: 10 mM * 1 mL in Ethanol; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2370. | |
| 24-Methylenecholesterol | 24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ostreasterol. CAS No. 474-63-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133968. | |
| 24-Methylenecycloartanyl ferulate | 24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 469-36-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8122. | |
| 24-Norursodeoxycholic acid | 24-norursodeoxycholic acid (Norucholic acid) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestatic, anti-inflammatory and anti-fibrotic properties. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Norucholic acid; nor-UDCA. CAS No. 99697-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101737. | |
| 24R-Calcipotriol | 24R-Calcipotriol (PRI 2202; Impurity D of Calcipotriol), an isomer of Calcipotriol (HY-10001), is a synthetic vitamin D analog. 24R-Calcipotriol exhibits synergistic antiproliferative effects with low-dose cytostatics in in vitro. 24R-Calcipotriol produces tumor growth inhibition when combined with Cyclophosphamide (HY-17420) and Cisplatin (HY-17394) in mice models. 24R-Calcipotriol can increase serum calcium levels and reduce blood leukocyte counts. 24R-Calcipotriol can be used for the research of mammary cancer and Lewis lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRI 2202; Impurity D of Calcipotriol. CAS No. 112827-99-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15266. | |
| (24S)-24,25-Dihydroxyvitamin D3 | (24S)-24,25-Dihydroxyvitamin D3 ((24S)-24,25-Dihydroxycholecalciferol) is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (24S)-24,25-Dihydroxycholecalciferol. CAS No. 55700-58-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15439. | |
| (24S,25)-Epoxycholesterol | 24S,25-Epoxycholesterol is an agonist for Liver X Receptor (LXR). 24S,25-Epoxycholesterol exhibits properties in regulating the cholesterol efflux[1], inhibiting tumor growth against gastric cancer and glioblastoma[2][3] and inducing apoptosis in BMMC cells[5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77058-74-3. Pack Sizes: 1 mg. Product ID: HY-W040150. | |
| 24(S)-Hydroxycholesterol | 24(S)-Hydroxycholesterol (24S-OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24(S)-Hydroxycholesterol (24S-OHC) is one of the most efficient endogenous LXR agonist known and is present in the brain and in the circulation at relatively high levels. 24(S)-Hydroxycholesterol (24S-OHC) is a very potent, direct, and selective positive allosteric modulator of NMDARs with a mechanism that does not overlapthat of other allosteric modulators[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 24S-OHC; 24S-HC; Cerebrosterol. CAS No. 474-73-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-16940. | |
| 2,5-Anhydro-D-mannitol, 97% | 2,5-Anhydro-D-mannitol, 97% is an antimetabolic fructose analogue. 2,5-Anhydro-D-mannitol, 97% depletes intracellular ATP, reduces oxygen consumption, regulates substrate oxidation, increases phosphomonoester levels, decreases inorganic phosphate levels, and promotes the release of intracellular calcium from intracellular calcium stores via phospholipase C-dependent activity in hepatocytes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 41107-82-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W039315. | |
| 2-5A TEA | 2-5A (2,5-ApApA; 2,5-trioligoadenylate; 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine) TEA is a 5'-triphosphorylated (2',5') oligoadenylate. 2-5A TEA is an immunotransmitter that fuels RNase L immunity. 2-5A TEA degrades viral mRNA and inhibits protein synthesis by binding to RNase L and activating its endoribonuclease activity. 2-5A TEA can be used in RSV and cancer research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,5-ApApA TEA; 2,5-trioligoadenylate TEA; 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine TEA. CAS No. 72351-33-8. Pack Sizes: 5.83 mg (100 mM * 50 μL in Water); 11.66 mg (100 mM * 100 μL in Water); 23.31 mg (100 mM * 200 μL in Water); 58.28 mg (100 mM * 500 μL in Water). Product ID: HY-173189B. | |
| 25C-NBOH hydrochloride | 25C-NBOH hydrochloride is a derivative of 2C-C having an N-(2-hydroxybenzyl) addition at the amine and is a potent agonist of 5-HT receptors that shows selectivity for 5-HT2A over 5-HT2C (EC50s = ~ 0.40 and 15 nM, respectively)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1539266-20-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121920. | |
| 2,5-Deoxyfructosazine | 2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 270912. CAS No. 17460-13-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-135078. | |
| 25-Desacetyl rifampicin | 25-Desacetyl rifampicin (Desacetylrifampicin) is a metabolite of Rifampin (HY-B0272) via β-esterase. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Desacetylrifampicin. CAS No. 16783-99-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-125587. | |
| 2',5'-Dideoxyadenosine | 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 μM. 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6698-26-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-135878. | |
| 2,5-Difluoroterephthalic acid | 2,5-Difluoroterephthalic acid (1,4-Benzenedicarboxylicacid,2,5-difluoro) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,4-Benzenedicarboxylicacid,2,5-difluoro. CAS No. 655-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W109864. | |
| 2,5-Dihydroxy-1,4-benzoquinone | 2,5-Dihydroxy-1,4-benzoquinone (DHBQ) is a redox-active quinone-based organic ligand with antibacterial activity that can be obtained from fungal metabolites. After 2,5-Dihydroxy-1,4-benzoquinone is incorporated into the Fe (dhbq) metal-organic framework, a two-electron redox process occurs, which helps improve the discharge capacity of Li+-ion battery cathodes. 2,5-Dihydroxy-1,4-benzoquinone can be used to construct conductive metal-organic frameworks suitable for Li+-ion battery cathodes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DHBQ. CAS No. 615-94-1. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W010323. | |
| 2,5-Dihydroxybenzoic acid | 2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of fibroblast growth factors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gentisic acid. CAS No. 490-79-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-W001179. | |
| 2,5-Dihydroxybenzoic acid (Standard) | 2,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of fibroblast growth factors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gentisic acid (Standard). CAS No. 490-79-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W001179R. | |
| 2,5-Dioxopyrrolidin-1-yl 3-((tert-butoxycarbonyl)amino)propanoate | 2,5-Dioxopyrrolidin-1-yl 3-((tert-butoxycarbonyl)amino)propanoate (Boc-Beta-Ala-OSu) is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Boc-Beta-Ala-OSu. CAS No. 32703-87-0. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W095737. | |
| 2,5-Dioxopyrrolidin-1-yl hept-6-ynoate | 2,5-Dioxopyrrolidin-1-yl hept-6-ynoate is an amine reactive four carbon reagent that can be used for derivatizing peptides, antibodies, amine coated surfaces etc. The alkyne group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. Uses: Scientific research. Category: Signaling pathways. CAS No. 917222-23-2. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-W451405. | |
| 2,5-Furandicarboxylic acid | 2,5-Furandicarboxylic acid, detected in human urine, is an important renewable biotechnological building block because it serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, plasticizers, fungicides, macrocyclic ligands and other products[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3238-40-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W002105. | |
| 2,5-Furandimethanol | 2,5-Furandimethanol (2,5-Bis(hydroxymethyl)furan) is a building block for the enzymatic synthesis of bio-based polyesters. 2,5-Furandimethanol is also a metabolite of Phellinus linteus. 2,5-Furandimethanol affects leukemia. 2,5-Furandimethanol can be used in fungal infection research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1883-75-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-W017782. | |
| 25-Hydroxycholesterol | 25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50?65 nM) and selective suppressor of IgA production by B cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 25-OHC. CAS No. 2140-46-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113134. | |
| 25-Hydroxycholesterol-d6 | 25-Hydroxycholesterol-d6 (25-OHC-d6) is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50?65 nM) and selective suppressor of IgA production by B cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 25-OHC-d6. CAS No. 88247-69-2. Pack Sizes: 1 mg. Product ID: HY-113134S. | |
| 25-Hydroxy VD2-d6 | 25-Hydroxy VD2-d6 is the deuterium labeled 25-Hydroxy VD2. Uses: Scientific research. Category: Signaling pathways. CAS No. 1262843-46-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-15328. | |
| 25I-NBOMe 4-methoxy isomer hydrochloride | 25I-NBOMe 4-methoxy isomer hydrochloride is an isomer of 25I-NBOMe. 25I-NBOMe is an agonist for 5-HT2A, that binds to rat 5-HT2A and human 5-HT2A with Ki of 0.087 nM and 0.044 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1566571-64-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W779640. | |
| (25S)-Δ7-Dafachronic acid | (25S)-Δ7-Dafachronic acid is a ligand and activator of DAF-12 receptor. DAF-12 is a nuclear hormone receptor that regulates larval diapause, developmental age, and adult longevity in Caenorhabditis elegans[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dafachronic acid A; Δ7-Dafachronic acid. CAS No. 949004-12-0. Pack Sizes: 100 μg; 500 μg. Product ID: HY-130221. | |
| 25S-Inokosterone | 25S-Inokosterone is a phytoecdysone in the roots of two same species of A. bidentata Blume and A. japonica Nakai, and two different species of C. capitata Moq and C. officinalis Kuan. 25S-Inokosterone has the potential for the LPS-induced acute kidney injury research[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 19595-18-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N4130. | |
| 2,6-Dichloro-4-iodopyridine | 2,6-Dichloro-4-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 98027-84-0. Pack Sizes: 5 g; 10 g. Product ID: HY-41945. | |
| 2,6-Dichlorocapronic acid xylidide | 2,6-Dichloro-N-(2,6-dimethylphenyl)hexanamide is a Bupivacaine (HY-B0405) impurity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1037184-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-W328520. | |
| 2,6-Dichloroquinone-4-chloroimide | 2,6-Dichloroquinone-4-chloroimide is a spray reagent for organic compounds. 2,6-Dichloroquinone-4-chloroimide can be used in thin-layer chromatograms and detecting phenol and its derivatives. 2,6-Dichloroquinone-4-chloroimide can be used as an optical sensor for rapid detection of permethrin in treated wood[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 101-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-W105135. | |
| 2,7-Dichlorodihydrofluorescein | 2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent reactive oxygen species (ROS) probe with an excitation wavelength of 485-500 nm and an emission wavelength of 515-530 nm. 2,7-Dichlorodihydrofluorescein is first hydrolyzed by intracellular esterases and then oxidized by ROS to generate non-biomembrane-permeable, highly fluorescent 2,7-dichlorofluorescein (DCF). The fluorescence intensity of DCF is positively correlated with the ROS concentration. 2,7-Dichlorodihydrofluorescein can undergo oxidation reactions with a variety of ROS (such as ·OH, H2O2, ONOO-, etc.) and is used to quantitatively detect the level of oxidative stress inside and outside cells. It is suitable for oxidative stress analysis in in vitro cell models and in vivo targeted delivery (such as liver-targeted liposomes)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DCFH2. CAS No. 106070-31-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153006. | |
| 2,7-Dichlorofluorescein diacetate | 2,7-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2,7-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DCFH2-DA. CAS No. 2044-85-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-126793. | |
| 2,7-Dimethylnaphthalene | 2,7-Dimethylnaphthalene is a selective cytochrome P450 1A2 (CYP1A2) enzyme inhibitor with an IC50 of 65 μM. 2,7-Dimethylnaphthalene can be used for the research of metabolic disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 582-16-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 1 g; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W045990. | |
| 27-Hydroxycholesterol | 27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 27-OHC. CAS No. 20380-11-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2371. | |
| 2,8-Dimethyladenosine | 2,8-Dimethyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63954-66-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-152702. | |
| 2A3 | 2A3 (2-aminopyridine-3-carboxylic acid imidazolide) is a T cell activator that specifically binds to CEACAM6 and CEACAM5. 2A3 exhibits enzymatic activity that catalyzes the glucuronidation of specific substrates (e.g., 1-naphthol), and possesses significant cytotoxic activity. When integrated into CAR T cells or used alone, 2A3 acts by inducing cytokine release, degranulation, and direct cytotoxicity. 2A3 kills pancreatic and breast cancer cells with high target antigen expression in vitro, and significantly inhibits the growth of pancreatic cancer xenografts in vivo. 2A3 broadly targets malignant tumors with overexpressed CEACAM5, CEACAM6, or co-expressed both, and shows high expression mainly in tissues such as the liver and colon. 2A3 serves as an important research tool for the immunotherapy of pancreatic and breast cancer[1][2]. 2A3 is a novel SHAPE reagent, which can be used for the analysis of RNA structure both in vitro and in vivo[3]. 2A3 is an electrophilic chemical probe that acylates the 2'-OH in the RNA backbone. 2A3 can be used for RNA SHAPE-MaP experiments and is capable of analyzing the RNA secondary structures at single nucleotide resolution. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-aminopyridine-3-carboxylic acid imidazolide. CAS No. 2765091-45-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164899. | |
| 2-Acetamidofluorene | 2-Acetamidofluorene is a potent carcinogenan. 2-Acetamidofluorene is can be used fot induction of hepatocellular carcinoma (HCC) and multiple primary tumours[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 53-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-W013514. | |
| 2'-Acetylacteoside | 2'-Acetylacteoside (2'-AA) is a natural compound with oral activity and blood-brain barrier permeability. 2'-Acetylacteosideexhibits MAO - B inhibitory activity (IC50 = 17.71 μM, Ki = 13.81 μM). 2'-Acetylacteoside downregulates the expression of RANK, TRAF6, NF - κB, NFATc1 and IKKβ, disrupts the RANKL/RANK interaction, blocks downstream signaling pathways, and increases the level of phosphorylated Akt. 2'-Acetylacteoside possesses potent anti-osteoclastogenic, anti-bone resorptive, pro-neurogenic, neuroprotective and antioxidant activities. 2'-Acetylacteoside can be used in the research of osteoporosis, ischemic stroke and Parkinson's disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2'-AA. CAS No. 94492-24-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-N0026. | |
| 2-Amino-2'-deoxyadenosine | 2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4546-70-7. Pack Sizes: 5 g. Product ID: HY-W016041. | |
| 2-Amino-3-carboxy-1,4-naphthoquinone | 2-Amino-3-carboxy-1,4-naphthoquinone is the electron transfer mediator. 2-Amino-3-carboxy-1,4-naphthoquinone changes glucose metabolism of the homofermentative lactic acid bacteria[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 173043-38-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8139. | |
| 2-Aminoacridone | 2-Aminoacridone is a widely used fluorophore (λexc=428 nm, λem=525 nm). Uses: Scientific research. Category: Signaling pathways. CAS No. 27918-14-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103594. | |
| 2-Amino benzamidoxime | 2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes[1].\n . Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABAO. CAS No. 16348-49-5. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-125372. | |
| 2-Aminoethyl diphenylborinate | 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-APB. CAS No. 524-95-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W009724. | |
| 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) | 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 173308-19-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-100138. | |
| 2-Aminoimidazole | 2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7720-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W062216. | |
| 2-Aminoindan-2-phosphonic acid | 2-Aminoindan-2-phosphonic acid is an inhibitor of phenylalanine ammonia-lyase (PAL). 2-Aminoindan-2-phosphonic acid reduces the biosynthesis and accumulation of total phenolic compounds in the suspension cell culture system of Cistanche[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 141120-17-4. Pack Sizes: 10 mM * 1 mL in Water; 10 mg; 25 mg; 50 mg. Product ID: HY-W004494. | |
| 2-Aminoindan-2-phosphonic acid hydrochloride | 2-Aminoindan-2-phosphonic acid hydrochloride is a competitive phenylalanine ammonia lyase (PAL) inhibitor that significantly decreases the levels of total phenolic compounds and PheGs in plant cultured cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1416354-35-2. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-W017692. | |
| 2-Aminopurine | 2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 452-06-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-W012642. | |
| 2-Aminoterephthalic acid | 2-Aminoterephthalic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10312-55-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g; 250 g. Product ID: HY-W004675. | |
| 2-Arachidonoylglycerol | 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system. Uses: Scientific research. Category: Signaling pathways. CAS No. 53847-30-6. Pack Sizes: 1 mg (26.4 mM * 100 μL in Acetonitrile). Product ID: HY-W011051. | |
| 2-Arachidonoylglycerol-d5 | 2-Arachidonoylglycerol-d5 is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system. Uses: Scientific research. Category: Signaling pathways. CAS No. 2522598-88-3. Pack Sizes: 100 μg (1.30 mM * 200 μL in Acetonitrile). Product ID: HY-W011051S1. | |
| 2-Arachidonoylglycerol-d8 | 2-Arachidonoylglycerol-d8 is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system. Uses: Scientific research. Category: Signaling pathways. CAS No. 924894-97-3. Pack Sizes: 25 μg (258.67 μM * 250 μL in Acetonitrile). Product ID: HY-W011051S. | |
| 2-Azido-2-deoxy-D-glucose, 98% | 2-Azido-2-deoxy-D-glucose, 98% (2-ADG, 98%) is a substrate of O-GlcNAc transferase (OGT). 2-Azido-2-deoxy-D-glucose, 98% can be transferred from UDP-GlcAz to proteins in vitro via OGT mediation. When delivered as AcGlcAz, 2-Azido-2-deoxy-D-glucose, 98% enables the labeling and investigation of O-GlcNAc-modified nuclear and cytoplasmic proteins in cells. 2-Azido-2-deoxy-D-glucose, 98% undergoes strain-promoted [3+2] azide-alkyne cycloaddition (SPAAC) with technetium-99m-labeled dibenzocyclooctyne derivatives in vivo. 2-Azido-2-deoxy-D-glucose, 98% can be used in sarcoma-related research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-ADG, 98%. CAS No. 56883-39-7. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W039939. | |
| 2'-Azido-2'-deoxyuridine | 2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1]. 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N3dUrd. CAS No. 26929-65-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-135957. | |
| 2BAct | 2BAct is a highly selective, orally active, and CNS-penetrant eIF2B (eukaryotic initiation factor 2B) activator with an EC50 of 33 nM. 2BAct prevents neurological defects caused by a chronic integrated stress response. 2BAct displays improved solubility and pharmacokinetics relative to eIF2B activator ISRIB trans-isomer (HY-12495)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2143542-28-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125021. | |
| 2-Benzylsuccinic acid | 2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an orally active carboxypeptidase A and Nna1 inhibitor. 2-Benzylsuccinic acid reduces cold hyperalgesia. 2-Benzylsuccinic acid can be used for the researches of neuropathic pain, non-alcoholic steatohepatitis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Benzylsuccinic acid. CAS No. 884-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-W044764. | |
| 2-Boc-2,6-Diazaspiro[3.3]heptane | 2-Boc-2,6-Diazaspiro[3.3]heptane is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1041026-70-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-30843. | |
| 2-Boc-2-Azaspiro[3.3]heptane-OH | 2-Boc-2-Azaspiro[3.3]heptane-OH is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1147557-97-8. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-20236. | |
| 2-Bromobenzene-1,3,5-tricarboxylic acid | 2-Bromobenzene-1,3,5-tricarboxylic acid (2-Bromo-benzene-1,3,5-tricarboxylic acid) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Bromo-benzene-1,3,5-tricarboxylic acid. CAS No. 13520-03-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W112569. | |
| 2-Bromohexadecanoic acid | 2-Bromohexadecanoic acid (2-Bromopalmitate; 2-BP) is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-Bromohexadecanoic acid inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Bromopalmitic acid; 2-Bromopalmitate. CAS No. 18263-25-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-111770. | |
| 2-Bromoisobutyryl bromide | 2-Bromoisobutyryl bromide (Bromodimethylacetyl bromide; α-Bromoisobutyryl bromide; 2-Bromoisobutylyl bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bromodimethylacetyl bromide; α-Bromoisobutyryl bromide. CAS No. 20769-85-1. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-Y0238. | |
| 2-Bromo-LSD | 2-Bromo-LSD (BOL-148) is a blood-brain barrier-permeable 5-HT2A partial agonist and competitive partial antagonist. 2-Bromo-LSD acts as both a potent partial agonist (with an EC50 of 0.81 nM for Gq dissociation) and a potent partial antagonist (with a KB of 0.18 nM for Gq dissociation) at the 5-HT2A receptor. 2-Bromo-LSD exhibits partial agonist activity at multiple aminergic GPCRs, including 5-HT2A. 2-Bromo-LSD lacks 5-HT2B agonist activity. 2-Bromo-LSD induces dendritogenesis and spinogenesis. 2-Bromo-LSD reverses the behavioral effects of chronic stress and increases active coping behaviors in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BOL-148; Bromolysergide. CAS No. 478-84-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121675. | |
| 2-Bromo-LSD D-Tartrate | 2-Bromo-LSD D-Tartrate (BOL-148 D-Tartrate) is a blood-brain barrier-permeable 5-HT2A partial agonist and competitive partial antagonist. 2-Bromo-LSD D-Tartrate acts as both a potent partial agonist (with an EC50 of 0.81 nM for Gq dissociation) and a potent partial antagonist (with a KB of 0.18 nM for Gq dissociation) at the 5-HT2A receptor. 2-Bromo-LSD D-Tartrate exhibits partial agonist activity at multiple aminergic GPCRs, including 5-HT2A. 2-Bromo-LSD D-Tartrate lacks 5-HT2B agonist activity. 2-Bromo-LSD D-Tartrate induces dendritogenesis and spinogenesis. 2-Bromo-LSD D-Tartrate reverses the behavioral effects of chronic stress and increases active coping behaviors in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BOL-148 D-Tartrate; Bromolysergide D-Tartrate. CAS No. 2855123-30-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121675A. | |
| 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran | 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 40365-61-5. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W128289. | |
| 2-Butenoyl coenzyme A lithium | 2-Butenoyl coenzyme A lithium is an inactivator and a substrate of Plasmodium falciparum enoyl-β-hydroxyacyl-acyl carrier protein (ACP) reductase and other enoyl-CoA reductases, and it is also the lithium salt of trans-2-methyl-2-butenoyl coenzyme A. 2-Butenoyl coenzyme A lithium acts on short-chain and medium-chain coenzyme A dehydrogenases as well as glutaryl-CoA dehydrogenase, and shows no activity against wild-type isovaleryl-CoA dehydrogenase. 2-Butenoyl coenzyme A lithium functions as a metabolite in the L-isoleucine catabolic pathway, and can serve as a substrate in the activity assay of 3-ketothiolase. 2-Butenoyl coenzyme A lithium is applicable to research related to 3-ketothiolase deficiency[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102680-35-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134421. | |
| 2-Carboxyphenol-d4 | 2-Carboxyphenol-d4 is the deuterium labeled 2-Carboxyphenol. 2-Carboxyphenol is a plant hormone and mediates host responses against microbial pathogens. Uses: Scientific research. Category: Signaling pathways. CAS No. 78646-17-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-W020005. | |
| 2-Chloro-5-(trifluoromethyl)pyrimidine | 2-Chloro-5-(trifluoromethyl)pyrimidine is a chemical intermediate. It can be used in the synthesis of inducers of intracellular STAT1 phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 69034-12-4. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W008510. | |
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