MedChemExpress MCE - Products

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.

Product
18:1 Liss Rhod PE 18:1 Liss Rhod (18:1 Lissamine rhodamine) PE is a fluorescent phospholipid and fluorescent probe.18:1 Liss Rhod PE admixes into phospholipid inks for large-scale monitoring of dip-pen nanolithography-generated lithographic structures via fluorescence microscopy.18:1 Liss Rhod PE undergoes phase separation or self-quenching under certain conditions in thin lipid membrane stacks[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 18:1 Lissamine rhodamine PE. CAS No. 384833-00-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-162543. MedChemExpress MCE
187-1, N-WASP inhibitor 187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 380488-27-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1045. MedChemExpress MCE
18α-Glycyrrhetinic acid 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-N0375. MedChemExpress MCE
18α-Glycyrrhizic acid 18α-Glycyrrhizic acid is a derivate of Glycyrrhizic acid. 18α-Glycyrrhizic acid has weak antihepatotoxic anti-inflammatory activities[1]. Uses: Scientific research. Category: Natural products. CAS No. 83896-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6911A. MedChemExpress MCE
18β-Glycyrrhetinic acid 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. Uses: Scientific research. Category: Signaling pathways. CAS No. 471-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-N0180. MedChemExpress MCE
18-Bromooctadecanoic acid 18-Bromooctadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 2536-38-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W613392. MedChemExpress MCE
18-HEPE 18-HEPE (18-Hydroxy-5(Z),8(Z),11(Z),14(Z),16(E)-eicosapentaenoic acid) is an ester product. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 18-Hydroxy-5(Z),8(Z),11(Z),14(Z),16(E)-eicosapentaenoic acid. CAS No. 141110-17-0. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol). Product ID: HY-101495. MedChemExpress MCE
18-Methyleicosanoic acid 18-Methyleicosanoic acid is a branched-chain fatty acid. 18-Methyleicosanoic acid has a hydrophobic surface and can act as a boundary lubricant[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 36332-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-121950. MedChemExpress MCE
18-Methyleicosanoic acid-d3 18-Methyleicosanoic acid-d3 is the deuterium labeled 18-Methyleicosanoic acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 2708278-14-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-121950S. MedChemExpress MCE
1,9-Dimethylmethylene blue 1,9-Dimethylmethylene blue is a photosensitizer, virus inactivator and hemoglobin oxidant derived from methylene blue. When activated, 1,9-Dimethylmethylene blue generates reactive oxygen species including singlet oxygen, and acts as a metachromatic dye. When activated in monomeric or dimeric form, 1,9-Dimethylmethylene blue induces photoinactivation of R17 phage and vesicular stomatitis virus and oxidizes hemoglobin via non-singlet oxygen reactive oxygen species or singlet oxygen-mediated pathways, respectively. The monomeric form, with higher nucleic acid affinity, achieves virus inactivation under specific conditions without forming methemoglobin. 1,9-Dimethylmethylene blue binds to substances such as glycosaminoglycans to produce color changes. Although it is susceptible to interference from non-glycosaminoglycan components in urine, it is still applicable to spectrophotometric analysis for glycosaminoglycan quantification. With these unique photochemical and binding properties, 1,9-Dimethylmethylene blue is widely used in studies of viral infections and related biochemical analyses[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23481-50-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-169798. MedChemExpress MCE
19-Hydroxybufalin 19-Hydroxybufalin is a bufadienolide, inhibits epithelial-mesenchymal transition and attenuates the migration and invasion of PC3 cells[1]. Uses: Scientific research. Category: Natural products. CAS No. 39844-86-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N7019. MedChemExpress MCE
1A-116 1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1430208-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104064. MedChemExpress MCE
1-Aminobenzotriazole 1-Aminobenzotriazole is a nonspecific and irreversible inhibitor of cytochrome P450 (P450). Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT; 3-Aminobenzotriazole. CAS No. 1614-12-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-103389. MedChemExpress MCE
1-Aminocyclopropane-1-carboxylic acid 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity.[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22059-21-8. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-30004. MedChemExpress MCE
1-Aminocyclopropane-1-carboxylic acid-d4 1-Aminocyclopropane-1-carboxylic acid-d4 is the deuterium labeled 1-Aminocyclopropane-1-carboxylic acid. Aminocyclopropane-1-carboxylic acid is an endogenous metabolite[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 84392-07-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-30004S. MedChemExpress MCE
1-Azakenpaullone 1-Azakenpaullone (1-Akp) is a highly selective and ATP-competitive inhibitor of glycogen synthase kinase-3 β (GSK-3β), with an IC50 value of 18 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Akp. CAS No. 676596-65-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-59090. MedChemExpress MCE
1-Benzyl-I3C 1-Benzyl-I3C is a NEDD4-1 inhibitor with significant anticancer activity. 1-Benzyl-I3C can directly inhibit the ubiquitination activity of NEDD4-1 with an IC50 of 12.3μM, which is significantly better than its precursor compound I3C of 284μM. 1-Benzyl-I3C and its analogs showed good effects in inhibiting the proliferation of human melanoma cells, which is roughly related to their potency as NEDD4-1 enzyme inhibitors. By combining in vitro ubiquitination experiments and thermal stability analysis, 1-Benzyl-I3C was shown to be able to bind to the catalytic HECT domain of NEDD4-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60941-76-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N10159. MedChemExpress MCE
1β-Hydroxydeoxycholic acid 1β-Hydroxydeoxycholic acid (1β-OH-DCA), a secondary bile acid, is a CYP3A biomarker. Deoxycholic acid is specifically metabolized into 1β-Hydroxydeoxycholic acid by CYP3A4 and CYP3A7 using recombinant human CYP450 enzymes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1β-OH-DCA. CAS No. 80434-32-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113482. MedChemExpress MCE
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester 1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a drug intermediate that can be used for the preparation of SMARCA bromodomain ligands[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 286961-14-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-40249. MedChemExpress MCE
1-Bromo-3-iodobenzene 1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 591-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1 k g. Product ID: HY-32149. MedChemExpress MCE
1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (BMIM-TFSI; BMI-TFSI) is an HIV-1 integrase inhibitor. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide weakly inhibits recombinant HIV-1 integrase 3'-processing or strand transfer activity. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide can be used for the research of HIV-1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMIM-TFSI; BMI-TFSI. CAS No. 174899-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g. Product ID: HY-W010937. MedChemExpress MCE
1-Deoxymannojirimycin hydrochloride 1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor. 1-Deoxymannojirimycin hydrochloride has antiviral activity against HIV?1 strains. 1-Deoxymannojirimycin hydrochloride increases high mannose structures. 1-Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73465-43-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W009783. MedChemExpress MCE
1-Deoxynojirimycin 1-Deoxynojirimycin (Duvoglustat) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin possesses antihyperglycemic, anti-obesity, and antiviral features[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Duvoglustat. CAS No. 19130-96-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14860. MedChemExpress MCE
1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine 1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine (1-EPA-2-OH-sn-glycerol-3-phosphocholine) is an ester product. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-EPA-2-OH-sn-glycerol-3-phosphocholine. CAS No. 162440-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-W777986. MedChemExpress MCE
1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride 1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25952-53-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-D0178. MedChemExpress MCE
1F-Fructofuranosylnystose 1F-Fructofuranosylnystose can be used in the synthesis of Fructooligosaccharides (FOSs). Fructooligosaccharides exhibit lots of beneficial effects on our health and have been used as food ingredients. Uses: Scientific research. Category: Natural products. CAS No. 59432-60-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N2577. MedChemExpress MCE
1G244 1G244 is a potent DPP8/9 inhibitor with IC50s of 12 nM and 84 nM, respectively. 1G244 does not inhibit DPPIV and DPPII. 1G244 induces apoptosis in multiple myeloma cells and has anti-myeloma effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 847928-32-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116304. MedChemExpress MCE
1H,1'H-4,4'-Bipyrazole 1H,1'H-4,4'-Bipyrazole (4-(1H-Pyrazol-4-yl)-1H-pyrazole) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-(1H-Pyrazol-4-yl)-1H-pyrazole. CAS No. 25240-33-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W112721. MedChemExpress MCE
1H-Benzotriazole-4,5,6,7-d4 1H-Benzotriazole-4,5,6,7-d4 is the deuterium labeled 1H-Benzo[d][1,2,3]triazole[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1185072-03-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-Y0688S. MedChemExpress MCE
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine is an endogenous metabolite present in Blood that can be used for the research of Pregnancy and Sepsis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 50930-23-9. Pack Sizes: 10 mM * 1 mL in Methanol; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-141616. MedChemExpress MCE
1-Hexadecanol-d5 1-Hexadecanol-d5 is the deuterium labeled 1-Hexadecanol[1]. 1-Hexadecanol is a fatty alcohol, a lipophilic substrate[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219799-18-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-B1465S2. MedChemExpress MCE
1H-pyrazole-3,5-dicarboxylic acid hydrate 1H-pyrazole-3,5-dicarboxylic acid hydrate (Pyrazole-3,5-dicarboxylic acid monohydrate) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrazole-3,5-dicarboxylic acid monohydrate. CAS No. 303180-11-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-W067376. MedChemExpress MCE
1'-Hydroxy bufuralol 1'-Hydroxy bufuralol is the main metabolite of Bufuralol (HY-105124) by the cytochrome P450 isoenzymes 2D1 and 2D2 (CYP2D1/2). 1'-Hydroxy bufuralol can be used to determine CYP2D1/2 enzyme activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 03-7410. CAS No. 57704-16-2. Pack Sizes: 1 mg. Product ID: HY-122277. MedChemExpress MCE
1-Hydroxyphenazine 1-Hydroxyphenazine (Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin) is an inhibitor for α-Amylase with an IC50 of 3.1 μg/mL[1]. 1-Hydroxyphenazine exhibits anticancer and anti-inflammatory activity against cells A549, 1321N1 and RAW264.7, antifungal and antibacterial activity against strains Candida albicans, Aspergillus fumigatus, Escherichia coli and Xanthomonas campestris[2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin. CAS No. 528-71-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W068682. MedChemExpress MCE
1-Isothiocyanato-PEG4-alcohol 1-Isothiocyanato-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1835759-69-7. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-141246. MedChemExpress MCE
1-Methyl-4-imidazoleacetic acid hydrochloride 1-Methyl-4-imidazoleacetic acid hydrochloride is a stable metabolite of Histamine (HY-B1204) that is produced by the oxidation of the primary metabolite, N-methylhistamine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 35454-39-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W060470. MedChemExpress MCE
1-Methyl-4-nitrosopiperazine 1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MNP; MeNP; N-Methyl-N'-nitrosopiperazine. CAS No. 16339-07-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W663740. MedChemExpress MCE
1-Methyl-7-nitroisatoic anhydride 1-Methyl-7-nitroisatoic anhydride (1M7) is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity, can be used for RNA structure analysis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1M7. CAS No. 73043-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg. Product ID: HY-D0913. MedChemExpress MCE
1-Methyladenine 1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T-A base pairs in double-stranded DNA into non-disruptive T (anti)m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, 1-Methyladenine transforms into cytotoxic DNA damage and blocks the replication process[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5142-22-3. Pack Sizes: 5 mg. Product ID: HY-113306. MedChemExpress MCE
1-Methyladenosine 1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15763-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-113081. MedChemExpress MCE
1-Methylbenzimidazole 1-Methylbenzimidazole is an imidazole compound. 1-Methylbenzimidazole functions as an electrolyte additive in dye-sensitized solar cells. 1-Methylbenzimidazole is promising for research of solar cell performance[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1632-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W010372. MedChemExpress MCE
1-Methylguanosine 1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N1-Methylguanosine. CAS No. 2140-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113136. MedChemExpress MCE
1-Methylhistamine dihydrochloride (Standard) 1-Methylhistamine dihydrochloride is a histamine metabolite[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6481-48-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W053787R. MedChemExpress MCE
1-Methyl-L-histidine-d3 1-Methyl-L-histidine-d3 is the deuterium labeled 1-Methyl-L-histidine. 1-Methyl-L-histidine is an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake. Uses: Scientific research. Category: Signaling pathways. CAS No. 91037-48-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W017006S. MedChemExpress MCE
1,N6-Ethenoadenosine 1,N6-Ethenoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39007-51-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137600. MedChemExpress MCE
1-Naphthyl PP1 1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-NA-PP 1. CAS No. 221243-82-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13941. MedChemExpress MCE
1-NBD-decanoyl-2-decanoyl-sn-glycerol 1-NBD-decanoyl-2-decanoyl-sn-glycerol is a diacylglycerol (DAG) derivative, which is labeled with a fluorescent group NBD. 1-NBD-decanoyl-2-decanoyl-sn-glycerol is the substrate for diacylglycerol kinase (DGK), and can be used for quantitative detection of the DGF enzyme kinetics in vitro, and the changes in DAG and PA during cell signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2309189-98-6. Pack Sizes: 500 μg (8.64 mM * 100μL in Ethanol); 1 mg (8.64 mM * 200μL in Ethanol). Product ID: HY-158800. MedChemExpress MCE
1-NM-PP1 1-NM-PP1, a cell-permeable PP1 analog, is a potent Src family kinases inhibitor with IC50s of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PP1 Analog II. CAS No. 221244-14-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13942. MedChemExpress MCE
1-Oleoyl-2-acetyl-sn-glycerol 1-Oleoyl-2-acetyl-sn-glycerol is a cell-permeable analog of diacylglycerol (DAG) and can activate Protein kinase C (PKC). 1-Oleoyl-2-acetyl-sn-glycerol can activate the TRPC channels-mediated specific Ca2+ influx. 1-Oleoyl-2-acetyl-sn-glycerol can stimulate superoxide-generation from human neutrophils. 1-Oleoyl-2-acetyl-sn-glycerol stimulates the formation of phosphatidylinositol 4-phosphate in intact human platelets. 1-Oleoyl-2-acetyl-sn-glycerol can stimulate ascites tumor cell proliferation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 86390-77-4. Pack Sizes: 5 mg (25.09 mM * 500 μL in Acetonitrile); 10 mg (25.09 mM * 1 mL in Acetonitrile); 25 mg (25.09 mM * 2.5 mL in Acetonitrile). Product ID: HY-131648. MedChemExpress MCE
1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product generated following NADPH oxidase activation and Lyso-PS signal transduction. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium signals through macrophage G2A to enhance the phagocytic uptake of PS-dependent apoptotic (apoptosis) neutrophils and PS-exposed activated neutrophils. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium enhances macrophage phagocytic uptake of apoptotic cells, carboxylate-modified microspheres, and PS-exposed non-apoptotic activated neutrophils. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium serves as an acyl acceptor substrate for the lysophosphatidyltransferase At1g78690p to generate diacylphosphatidylserine. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium reduces the secretion of IL-8 and decreases the proportion of viable colon cancer cells. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium is applicable to studies on peritonitis and inflammatory bowel disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 18:1 Lyso-PS. CAS No. 326589-90-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-126213. MedChemExpress MCE
1-Oleoyl lysophosphatidic acid 1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant lysophosphatidic acid (LPA) species with high biological activity due to its strong affinity for the LPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation[1]. 1-Oleoyl lysophosphatidic acid increases SRE-driven β-galactosidase activity[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Oleoyl-sn-glycero-3-phosphate; 1-Oleoyl-LPA. CAS No. 65528-98-5. Pack Sizes: 1 mg (22.91 mM * 100 μL in Ethanol); 5 mg (22.91 mM * 500 μL in Ethanol); 10 mg (22.91 mM * 1 mL in Ethanol); 25 mg (22.91 mM * 2.5 mL in Ethanol). Product ID: HY-137862. MedChemExpress MCE
1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, a potent bioactive phospholipid, is a LPA receptor activator. 1-Oleoyl lysophosphatidic acid sodium can promote mitosis by inducing DNA synthesis. 1-Oleoyl lysophosphatidic acid sodium is also involved in normal and pathological emotional responses, including anxiety and depression[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Oleoyl-sn-glycero-3-phosphate sodium; 1-Oleoyl-LPA sodium. CAS No. 325465-93-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107614. MedChemExpress MCE
1-Oleoyl-sn-glycero-3-phosphocholine 1-Oleoyl-sn-glycero-3-phosphocholine (18:1 Lyso PC), a lysophospholipid, is a GPR82 inhibitor. 1-Oleoyl-sn-glycero-3-phosphocholine abrogates constitutive Gi-coupled GPR82 activity, shifts active/inactive equilibrium to inactive, suppresses Gi protein activation, increases cAMP production, and decreases GTPγS binding to Gαi proteins. 1-Oleoyl-sn-glycero-3-phosphocholine contributes to adipocyte lipolysis regulation.1-Oleoyl-sn-glycero-3-phosphocholine exhibits reduced serum levels in mouse models of steatohepatitis, linked to hepatic Lpcat 1-4 up-regulation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 18:1 Lyso PC. CAS No. 19420-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W140439. MedChemExpress MCE
1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is an oxidized phospholipid. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine reduces the viability of HUVECs, increases the levels of ferrous ions and lipid peroxidation, promotes the production of superoxide anions, and decreases the levels of glutathione and GPX4 in cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine upregulates the mRNA and protein levels of FABP3 in HUVECs, impairs mitochondrial membrane potential, and induces ferroptosis-related changes as well as mitochondrial dysfunction and damage. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine activates caspase-11 and promotes the continuous release of IL-1β from macrophages and dendritic cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine inhibits the proliferation of aortic smooth muscle cells and induces apoptosis in these cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is applicable to relevant research on atherosclerosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PGPC. CAS No. 89947-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-W040255. MedChemExpress MCE
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE also acts as an immune response regulator and toxicity alleviator produced by Microcystis aeruginosa under Cu2+ stress[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 53862-35-4. Pack Sizes: 5 mg. Product ID: HY-141617. MedChemExpress MCE
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE) is a lipid, which promotes nucleic acid such as sRNA to absorb and enter the target cell[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine. CAS No. 26662-95-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-120991. MedChemExpress MCE
1-Palmitoyl-2-oleoylphosphatidylethanolamine 1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: POPE. CAS No. 10015-88-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-167545. MedChemExpress MCE
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: POPC. CAS No. 26853-31-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-130462. MedChemExpress MCE
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-POPE; 16:0-18:1 PE. CAS No. 26662-94-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W583868. MedChemExpress MCE
1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium (16:0-18:1 PS (POPS)) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 16:0-18:1 PS (POPS). CAS No. 321863-21-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W714524. MedChemExpress MCE
1-Palmitoyl-2-oleoyl-sn-glycerol 1-Palmitoyl-2-oleoyl-sn-glycerol is a diacylglycerol hormogonium inducer that can be isolated from the coralloid roots of Cycas revoluta. 1-Palmitoyl-2-oleoyl-sn-glycerol promotes the differentiation of filamentous Nostoc cell aggregates into motile hormogonia, and further induces the formation of dense bundle-like structures. 1-Palmitoyl-2-oleoyl-sn-glycerol is not only commonly used as a diacylglycerol standard, but also can effectively identify and separate glycerophosphate-containing phospholipid enantiomers after acetylation. 1-Palmitoyl-2-oleoyl-sn-glycerol is also used to study cyanobacterial developmental mechanisms and lipid analysis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 29541-66-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-134200. MedChemExpress MCE
1-Palmitoyl-2-(propargylacetyl)-sn-glycero-3-phosphocholine 1-Palmitoyl-2-(propargylacetyl)-sn-glycero-3-phosphocholine is a phosphocholine containing an azide-reactive propargyl on one of its tails and a positively charged quaternary amine head. Uses: Scientific research. Category: Signaling pathways. CAS No. 1353897-91-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172516. MedChemExpress MCE
1-Palmitoyl-sn-glycero-3-phosphocholine 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 16:0 Lyso PC. CAS No. 17364-16-8. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-125783. MedChemExpress MCE
1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1 1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1 (16:0 Lyso PC-d9-1) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 16:0 Lyso PC-d9-1. CAS No. 182257-09-6. Pack Sizes: 1 mg. Product ID: HY-125783S3. MedChemExpress MCE
1-Pyrenebutyric acid 1-Pyrenebutyric acid is a fluorescence probe whose fluorescence lifetime depends on local oxygen and free radical concentrations. 1-Pyrenebutyric acid is used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme. 1-Pyrenebutyric acid can also be used for the measurement of free radicals in solution and in living cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3443-45-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W103047. MedChemExpress MCE
1-Pyrenebutyric acid N-hydroxysuccinimide ester 1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker and interface coupling agent that can be used to prepare electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester immobilizes SARS-CoV-2 spike antibodies on graphene sheets. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is often used as an activation reagent for carboxylic acids in organic chemistry or biochemistry[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114932-60-4. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-W013151. MedChemExpress MCE
(1R,1'S,3'R/1R,1'R,3'S)-L-054,264 (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a selective non-peptide human somatostatin receptor subtype 2 (sst2) agonist. (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 can be used in the study of retinal neuromodulation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 208706-12-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108501. MedChemExpress MCE
(1R,2R)-2-PCCA hydrochloride (1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC50 of 3 nM in cell-free assay, and 603 nM in cell assay. Uses: Scientific research. Category: Signaling pathways. CAS No. 1609563-71-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100013A1. MedChemExpress MCE
(1R,2R)-ML-SI3 (1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of three isoforms of TRPML. (1R,2R)-ML-SI3 inhibits TRPMLs with IC50s of 1.6 μM (TRPML1), 2.3 μM (TRPML2), and 12.5 μM (TRPML3), respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-trans-ML-SI3. CAS No. 2418594-00-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134819A. MedChemExpress MCE
(1R,2S)-Xeruborbactam disodium (1R,2S)-Xeruborbactam disodium is a boronic acid derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170836-14-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136072A. MedChemExpress MCE

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