MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| (1R,3R)-RSL3 | (1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219810-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100218C. |  |
| (1R,3S)-Compound E | (1R,3S)-Compound E is the isomer of Compound E (HY-14176), and can be used as an experimental control. Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 504428-17-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-14176A. | |
| (1R,3S)-RSL3 | (1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT22 wild-type cells with EC50 values of 5.2 μM and 0.004 μM, rspectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219810-13-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100218B. | |
| (1R,9R)-Exatecan mesylate | (1R,9R)-Exatecan mesylate ((1R,9R)-DX8951f) is a non-prodrug camptothecin derivative and a potent topoisomerase I inhibitor (IC50=0.975 μg/mL in mice and 0.82 μg/mL in humans). (1R,9R)-Exatecan mesylate blocks enzyme activity and induces apoptosis by stabilizing the enzyme-DNA cleavable complex. (1R,9R)-Exatecan mesylate not only effectively inhibits the proliferation of various malignant tumor cells and tumor growth, but also circumvents P-glycoprotein-mediated multidrug resistance. (1R,9R)-Exatecan mesylate is widely used in preclinical studies of multiple cancers including pancreatic cancer, lung cancer, breast cancer, and leukemia[1][2]. The low-activity isomer of (1R,9R)-Exatecan mesylate is (1S,9R)-Exatecan mesylate (HY-13631I). Uses: Scientific research. Category: Signaling pathways. Alternative Names: (1R,9R)-DX8951f. CAS No. 2938875-39-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13631J. | |
| 1R-cis-Permethrin | 1R-cis-Permethrin is an insecticide and neurotoxin. 1R-cis-Permethrin affects neuron membranes by prolonging sodium channel activation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1R-cis-NRDC-143. CAS No. 54774-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-B0887C. | |
| (1S,2S)-ML-SI3 | (1S,2S)-ML-SI3 is a trans-isomer of ML-SI3 that targets all three isoforms of TRPML. (1S,2S)-ML-SI3 is an activator of TRPML2 and TRPML3 (EC50=2.7 μM/10.8 μM) and a potent inhibitor of TRPML1 (IC50=5.9 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-trans-ML-SI3. CAS No. 2563870-87-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134819. | |
| (1S,9R)-Exatecan mesylate | (1S,9R)-Exatecan mesylate ((1S,9R)-DX8951f) is a non-prodrug camptothecin derivative and a topoisomerase I inhibitor (IC50=0.975 μg/mL in mice and 0.82 μg/mL in humans). (1S,9R)-Exatecan mesylate blocks enzyme activity and induces apoptosis by stabilizing the enzyme-DNA cleavable complex. (1S,9R)-Exatecan mesylate not only effectively inhibits the proliferation of various malignant tumor cells and tumor growth, but also circumvents P-glycoprotein-mediated multidrug resistance. (1S,9R)-Exatecan mesylate is widely used in preclinical studies of various cancers such as pancreatic cancer, lung cancer, breast cancer, and leukemia[1][2]. The chiral isomer of (1S,9R)-Exatecan mesylate is (1R,9R)-Exatecan mesylate (HY-13631J). Uses: Scientific research. Category: Signaling pathways. Alternative Names: (1S,9R)-DX8951f. CAS No. 2938875-54-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631I. | |
| (1S)-Calcitriol | (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1α,25-Dihydroxy-3-epi-vitamin-D3. CAS No. 61476-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10002A. | |
| 1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine | 1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1). CAS No. 6418-95-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W583869. | |
| 1-Stearoyl-sn-glycero-3-phosphocholine | 1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 18:0 Lyso-PC; LPC(18:0). CAS No. 19420-57-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-125771. | |
| 1-Thio-β-D-glucose sodium | 1-Thio-β-D-glucose sodium is the sodium salt form of 1-Thio-β-D-glucose. 1-Thio-β-D-glucose forms hydrophilic self-assembled monolayer with metal, stablizes the lipid bilayer and protects the proteins from denaturation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10593-29-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-115419. | |
| 1-Thioglycerol | 1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations. Uses: Scientific research. Category: Signaling pathways. Alternative Names: alpha-Thioglycerol. CAS No. 96-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g. Product ID: HY-W010572. | |
| 1V209 | 1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects. 1V209 can be conjugated with various polysaccharides to improve its water solubility, and enhance its efficacy, and maintain low toxicity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TLR7 agonist T7. CAS No. 1062444-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115400. | |
| 20-5,14-HEDE | 20-5,14-HEDE (WIT003) is an analog of 20-HETE. 20-5,14-HEDE activates PI3K/Akt signaling pathway, thereby exhibiting anti-apoptotic and cell survival promoting effects. 20-5,14-HEDE is the agonist for 20-HETE that increases intracellular Ca2+ concentrations, thereby enhancing vasoconstriction[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WIT003. CAS No. 240427-86-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-160099. | |
| 20-5,14-HEDGE | 20-5,14-HEDGE is a 20-HETE analog. 20-5,14-HEDGE induces cell death in organotypic hippocampal slice cultures (OHSCs). 20-5,14-HEDGE enhances ROS production and reduces hypoxia-reoxygenation (HR)-induced apoptosis in ex vivo rat lung slices. 20-5,14-HEDGE protects against lung ischemic reperfusion injury in rats. 20-5,14-HEDGE can be used for the study of pulmonary vascular signaling and lung injury-related research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1092380-14-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148226. | |
| 20-Deoxyingenol | 20-Deoxyingenol, a diterpene, is isolated from the roots of Euphorbia kansui. 20-Deoxyingenol can promote autophagy and lysosomal biogenesis by promoting the nuclear translocation of transcription factor EB (TFEB) in vitro. 20-Deoxyingenol can be used for the research of osteoarthritis (OA)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 54706-99-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N0866. | |
| 20-HEDE | 20-HEDE (WIT 002) is an antagonist of 20-hydroxyeicosatetraenoic acid (20-HETE). Uses: Scientific research. Category: Signaling pathways. Alternative Names: WIT 002. CAS No. 240427-90-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101527. | |
| (20R)-Protopanaxadiol | (20R)-Protopanaxadiol is a metabolite of ginsenosides. (20R)-Protopanaxadiol has anti-inflammatory and antibacterial activities, but shows no significant cytotoxicity against tumor cell lines. In addition, (20R)-Protopanaxadiol can inhibit the uptake of 2-deoxy-D-glucose (2-DG)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7755-1-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2040. | |
| 20(R)-Protopanaxatriol | 20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh. Uses: Scientific research. Category: Natural products. Alternative Names: 20(R)-APPT. CAS No. 1453-93-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0798. | |
| 20(S),24(R)-Ocotillol | 20(S),24(R)-Ocotillol is isolated from Panax ginseng[1]. Uses: Scientific research. Category: Natural products. CAS No. 69926-31-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6262. | |
| 20(S)-Ginsenoside Rg3 | 20(S)-Ginsenoside Rg3 is the main component of Panax ginseng C. A. Meyer. Ginsenoside Rg3 inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S)-Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 20(S)-Propanaxadiol; S-ginsenoside Rg3. CAS No. 14197-60-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0603. | |
| 20(S)-Hydroxycholesterol | 20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator that selectively targets the Smoothened (Smo) of the Hedgehog pathway with an EC50 of ~30 μM (Hedgehog). 20(S)-Hydroxycholesterol binds to the extracellular cysteine-rich domain (CRD) of Smo in a stereoselective manner, activating downstream Gli transcription factors (without inducing transcription of receptor genes in the Wnt pathway). 20(S)-Hydroxycholesterol enhances osteogenic differentiation of bone marrow stromal cells and synergistically activates the Raf/MEK/ERK pathway with Simvastatin (HY-17502) to promote bone regeneration. 20(S)-Hydroxycholesterol can be used to study the mechanisms of developmental biology, oncology, bone, and angiogenesis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 20α-Hydroxycholesterol. CAS No. 516-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12316. | |
| 20-SOLA | 20-SOLA is an orally active 20-HETE antagonist. 20-SOLA greatly ameliorates changes in blood pressure and renal injury associated with a Streptozotocin (STZ) (HY-13753)-diabetic mouse model. 20-SOLA facilitates the restoration of coronary collateral growth (CCG) after ischemic injury. 20-SOLA can be studied for research in cardiovascular diseases and diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3084781-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160186. | |
| 20S Proteasome activator 1 | 20S Proteasome activator 1 is a potent 20S proteasome activator with EC200 values of 0.3 μM, 0.7 μM and 1.8 μM for trypsin-like site, chymotrypsin-like site and caspase-like site. 20S Proteasome activator 1 translates well in a cellular system, preventing the accumulation of the pathogenic A53T mutant of α-synuclein. 20S Proteasome activator 1 can be used for researching neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2761578-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150602. | |
| (20S)-Protopanaxadiol | 20S-protopanaxadiol (aPPD) is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 20-Epiprotopanaxadiol; 20(S)-APPD. CAS No. 30636-90-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-N0797. | |
| (20S)-Protopanaxatriol | (20S)-Protopanaxatriol is a metabolite of ginsenoside. (20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and estrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 20(S)-APPT; g-PPT. CAS No. 34080-08-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0835. | |
| 21-Deoxycortisol | 21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 641-77-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-113405. | |
| 21-Deoxy cortisone | 21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is formed from 11-ketoprogesterone by the cytochrome P450 (CYP) isozyme CYP17A1, but can also be produced by oxidation of 21-deoxycortisone (HY-113405) by 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). Congenital adrenal hyperplasia is an inborn error of metabolism characterized by a deficiency of 21-hydroxylase, and 21-Deoxy Cortisone levels are elevated in patients with congenital adrenal hyperplasia. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 21-Desoxycortisone; NSC 38722. CAS No. 1882-82-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-W741510. | |
| 21-Desacetyldeflazacort | 21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 21-desDFZ. CAS No. 13649-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-100085. | |
| 2,2'-(2,5-Dihydroxy-1,4-phenylene)diacetic acid | 2,2'-(2,5-Dihydroxy-1,4-phenylene)diacetic acid (2,5-Dihydroxy-p-benzenediacetic acid) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,5-Dihydroxy-p-benzenediacetic acid. CAS No. 5488-16-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W036197. | |
| 2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid | 2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid is a PROTACT linker and can be used for synthesis of P60-L3-VHL (HY-162943). 2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3036674-82-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-162947. | |
| 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide | 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide (N-Methyl-n-trimethylsilyltrifluoroacetamide) is an ester product commonly used for silylation reactions in analyticalchemistry. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in the derivatization step of metabolomics analysis with gas chromatography/mass spectrometry (GC/MS) or as a derivatization reagent in GC with flame ionization detection analysis. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in research for studying Tamoxifen (HY-13757A) resistant breast cancer cells and other disease pathways[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Methyl-n-trimethylsilyltrifluoroacetamide. CAS No. 24589-78-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W089645. | |
| 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride | 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1035373-85-3. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-W096093. | |
| 2,2'-Bipyridine | 2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products. 2,2'-Bipyridine is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center. 2,2'-Bipyridine shows robust redox stability and hyperglycemic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 366-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0020. | |
| 2,2'-Bipyridine-5,5'-diol | 2,2'-Bipyridine-5,5'-diol (5,5'-Dihydroxy-2,2'-bipyridyl) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,5'-Dihydroxy-2,2'-bipyridyl. CAS No. 2326-78-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W034689. | |
| 2,2-Difluorodeoxyuridine | 2,2-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2,2-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2,2-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: dFdU; 2',2'-Difluoro-2'-deoxyuridine. CAS No. 114248-23-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138253. | |
| 2,2-Difluorodeoxyuridine-13C,15N2 | 2,2-Difluorodeoxyuridine-13C,15N2 (dFdU-13C,15N2) is a 13C- and 15N-labeled compound. 2,2-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2,2-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2,2-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: dFdU-13C,15N2; 2',2'-Difluoro-2'-deoxyuridine-13C,15N2. CAS No. 1233921-75-9. Pack Sizes: 1 mg. Product ID: HY-138253S. | |
| 2,2-Difluorodeoxyuridine (Standard) | 2,2-Difluorodeoxyuridine (Standard) is the analytical standard of 2,2-Difluorodeoxyuridine. This product is intended for research and analytical applications. 2,2-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2,2-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2,2-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: dFdU (Standard); 2',2'-Difluoro-2'-deoxyuridine (Standard). CAS No. 114248-23-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138253R. | |
| 2,2-Dipyridyl disulfide | 2,2-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation-reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2127-3-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y1666. | |
| 2-(2-Methylenecyclopropyl)acetic acid | 2-(2-Methylenecyclopropyl)acetic acid is an ester product. Uses: Scientific research. Category: Signaling pathways. CAS No. 1073-00-3. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-W710928. | |
| 2,2-Oxybis(ethylamine) | 22-Oxybis(ethylamine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2752-17-2. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-140208. | |
| 2-(2-Phenylethyl)chromone | 2-(2-Phenylethyl) chromone (Flidersiachromone) is a chromone derivative and antioxidant. 2-(2-Phenylethyl) chromone scavenges ABTS·+ free radicals, and its derivatives exhibit diverse activities including anti-inflammatory, neuroprotective, anti-tumor, and α-glucosidase inhibitory effects. 2-(2-Phenylethyl) chromone is applicable to experimental research in fields such as inflammation-related diseases, tumors, and neurodegenerative diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Flidersiachromone. CAS No. 61828-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8220. | |
| 22(R)-Hydroxycholesterol | 22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Narthesterol. CAS No. 17954-98-2. Pack Sizes: 10 mM * 1 mL in Ethanol; 1 mg; 5 mg; 10 mg. Product ID: HY-116969. | |
| 22-SLF | 22-SLF is a PROTAC degrader, that degrades FK506-binding protein 12 (FKBP12) with a DC50 of 0.5 μM. 22-SLF interacts with C227 and C228 in FBXO22 to induce a ternary complex between FKBP12 and FBXO22, and degrades FKBP12 in a FBXO22-dependent manner. 22-SLF can be used for fundamental cancer research as a probe to study the FBXO22 degradation pathway. (Pink: FKBP12 ligand (HY-114872); Black: Linker (HY-163821); Blue: FBXO22 ligand (HY-163826))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3079209-82-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163807. | |
| 23,25-Dihydroxy-24-oxovitamin D3 | 23,25-Dihydroxy-24-oxovitamin D3 is a major metabolite of 24(R),25-Dihydroxyvitamin D3. 23,25-Dihydroxy-24-oxovitamin D3 can be used for the research of metabolic diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 24-Oxo-23,25-dihydroxyvitamin D3. CAS No. 84164-55-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-18646. | |
| 2,3-Butanediol-d8 | 2,3-Butanediol-d8 is the deuterium labeled 2,3-Butanediol (HY-128387)[1]. 2,3-Butanediol is microbially derived compound that is a discriminating urinary biomarker of Fmo5-/- mice. 2,3-Butanediol prevents age-related increases in the plasma concentration of cholesterol. 2,3-Butanediol has potential applications in the manufacture of printing inks, perfumes, fumigants, moistening and softening agents, plasticizers, and as a carrier for pharmaceuticals[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 347841-77-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128387S1. | |
| 23-c-di-AM(PS)2 (Rp,Rp) | 23-c-di-AM(PS)2 (Rp,Rp) (ADU-S100), an activator of stimulator of interferon genes (STING), leads to potent and systemic tumor regression and immunity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADU-S100; MIW815; ML RR-S2 CDA. CAS No. 1638241-89-0. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12885. | |
| 23-c-di-AM(PS)2 (Rp,Rp) ammonium salt | 23-c-di-AM(PS)2 (Rp,Rp) ammonium salt (ADU-S100 ammonium salt), an activator of stimulator of interferon genes (STING), leads to potent and systemic tumor regression and immunity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADU-S100 ammonium salt; MIW815 ammonium salt; ML RR-S2 CDA ammonium salt. CAS No. 1638750-96-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12885B. | |
| 23-c-di-AM(PS)2 (Rp,Rp) disodium salt | 23-c-di-AM(PS)2 (Rp,Rp) disodium salt (ADU-S100 disodium salt) is an activator of stimulator of interferon genes (STING). Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADU-S100 disodium salt; MIW815 disodium salt; ML RR-S2 CDA disodium salt. CAS No. 1638750-95-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12885A. | |
| 2',3'-cGAMP | 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2'-3'-cyclic GMP-AMP. CAS No. 1441190-66-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100564. | |
| 2',3'-cGAMP sodium | 2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2'-3'-cyclic GMP-AMP sodium. CAS No. 2734858-36-5. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-100564A. | |
| 2',3'-cGMP sodium | 2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Guanosine 2',3'-cyclic monophosphate sodium salt. CAS No. 15718-49-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N8245. | |
| 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid | N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Neu5Ac2en; DANA. CAS No. 24967-27-9. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125798. | |
| 2,3-Diaminonaphthalene | 2,3-Diaminonaphthalene is a fluorescent reagent used to detect selenium and nitric oxide (NO). 2,3-Diaminonaphthalene binds to selenium to form pyrazolene selenol, with excitation/emission maxima at 365 nm and 525 nm, respectively. 2,3-Diaminonaphthalene binds to NO2- to form the fluorescent product, 1-(H)-napthotriazole, with excitation/emission maxima at 360 nm and 440 nm, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 771-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-D0073. | |
| 2,3-Dihydro-3-methoxywithaferin A | 2,3-Dihydro-3-methoxywithaferin A is an analogue of 2,3-dihydrowithaferin-A. 2,3-Dihydro-3-methoxywithaferin A inhibits proiiferation of P388 cells[1]. Uses: Scientific research. Category: Natural products. CAS No. 21902-96-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10350. | |
| 2,3-Diphospho-D-glyceric acid pentasodium salt | 2,3-Diphospho-D-glyceric acid (2,3-DPG) pentasodium salt is a hemoglobin binder and vascular calcification inhibitor that reduces the oxygen affinity of hemoglobin. 2,3-Diphospho-D-glyceric acid pentasodium salt also specifically delays the transformation of colloidal calciprotein particles into crystalline forms, thereby effectively inhibiting vascular smooth muscle cell calcification without affecting the normal formation of osteoid nodules in osteoblast-like cells. 2,3-Diphospho-D-glyceric acid pentasodium salt shows no cytotoxicity to tested cell lines and only weakly interferes with β-hematin formation mediated by glyceryl monopalmitate. 2,3-Diphospho-D-glyceric acid pentasodium salt can be used to study the pathological mechanisms of vascular calcification and malaria-related conditions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,3-DPG pentasodium salt. CAS No. 102783-53-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-138822. | |
| 2,3-Diphosphoglyceric acid pentasodium | 2,3-Diphosphoglyceric acid (2,3-DPG) pentasodium is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid pentasodium stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2,3-Diphosphoglyceric acid pentasodium binds to hemoglobin and decrease its affinity for oxygen[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,3-DPG pentasodium. CAS No. 1287756-01-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113050A. | |
| 2,3-Pentanedione-d5 | 2,3-Pentanedione-d5 is the deuterium labeled 2,3-Pentanedione (HY-W012998). 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352431-46-0. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 10 mg; 25 mg; 100 mg. Product ID: HY-W012998S. | |
| 24:0 Lyso PC | 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 325171-59-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-138622. | |
| 24, 25-Dihydroxy VD2 | 24,25-Dihydroxy VD2 (24,25-Dihydroxy vitamin D2) is a hydroxylated metabolite and derivative of Vitamin D2 HY-76542 (HY-76542)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 24,25-Dihydroxy vitamin D2. CAS No. 58050-55-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-76801. | |
| 2,4,6-Tri([1,1'-biphenyl]-4-yl)-1,3,5-triazine | 2,4,6-Tri([1,1'-biphenyl]-4-yl)-1,3,5-triazine (Tris-biphenyl triazine) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tris-biphenyl triazine. CAS No. 31274-51-8. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W075183. | |
| 2,4,6-Tri-2-pyridinyl-1,3,5-triazine | 2,4,6-Tri-2-pyridinyl-1,3,5-triazine (NSC 112125) is a colorimetric reagent for detecting iron. 2,4,6-Tri-2-pyridinyl-1,3,5-triazine forms a complex with Fe (II) and can be quantified as a measure of iron concentration by colorimetric detection at 594 nm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 112125; 2,4,6-Tipyidyl-s-tiazie. CAS No. 3682-35-7. Pack Sizes: 5 g; 10 g. Product ID: HY-D0221. | |
| 2,4,6-Trihydroxybenzoic acid | 2,4,6-Trihydroxybenzoic acid, the flavonoid metabolite, is a CDK inhibitor. 2,4,6-Trihydroxybenzoic acid can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g. Product ID: HY-W077292. | |
| 2,4,6-Triiodophenol | 2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 609-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W073687. | |
| (2,4,6-Trimethyl-phenoxy)-acetic acid | (2,4,6-Trimethyl-phenoxy)-acetic acid is an organic compound with excellent herbicide activity. This compound can effectively inhibit weed growth and help increase crop yields. (2,4,6-Trimethyl-phenoxy)-acetic acid shows strong selectivity against specific types of weeds. Uses: Scientific research. Category: Signaling pathways. CAS No. 13333-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W264306. | |
| 2,4-D | 2,4-D (2, 4-dichlorophenoxyacetic acid) is a selective herbicide that can be used for the control of broad-leaved weeds. 2,4-D can induce apoptosis. 2,4-D inhibits DNA and protein synthesis, thereby preventing normal plant growth and development[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-Dichlorophenoxyacetic acid. CAS No. 94-75-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-18572. | |
| 2,4-D-13C6 | 2,4-D-13C6 is the 13C-labeled 2,4-D (HY-18572). 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-Dichlorophenoxyacetic acid-13C6. CAS No. 150907-52-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-18572S. | |
| 2,4-D-d5 | 2,4-D-d5 (2,4-Dichlorophenoxyacetic acid-d5) is the deuterium labeled 2,4-D (HY-18572)[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352438-69-8. Pack Sizes: 1 mg. Product ID: HY-18572S2. | |
| 2,4-Diacetylphloroglucinol | 2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2161-86-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118448. | |
| 2,4-Diamino-6-hydroxypyrimidine | 2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis). 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56-06-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-100954. | |
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