MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Sulfobetaine 10 | Sulfobetaine 10, is a zwitterionic surfactant commonly used in biochemistry and biophysics. It is commonly used to dissolve membrane proteins and other hydrophobic molecules in aqueous solutions. Sulfobetaine 10 has both positively and negatively charged groups in its structure, which allows it to maintain a neutral charge in solution and reduces its tendency to denature proteins. It is considered a mild, non-denaturing surfactant and is widely used in protein research. Uses: Scientific research. Category: Signaling pathways. CAS No. 15163-36-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-126377. |  |
| Sulfobetaine-18 | 3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA. Uses: Scientific research. Category: Signaling pathways. CAS No. 13177-41-8. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-W008974. | |
| Sulfobromophthalein disodium salt | Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of agents and metabolites[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bromosulfophthalein disodium salt. CAS No. 71-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-D0217. | |
| Sulfo-Cy3 amine | Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfo-Cyanine3 amine. CAS No. 2183440-43-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1272. | |
| Sulfo-Cy3 maleimide potassium | Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1656990-68-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-137098. | |
| Sulfo-Cy3(Me)COOH | Sulfo-Cy3(Me)COOH is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1121756-11-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1365. | |
| Sulfo-Cy5.5 Azide | Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1955527-41-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151711. | |
| Sulfo-CY-5.5 NHS ester tripotassium | Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfo-Cyanine5.5 NHS ester tripotassium. CAS No. 2419286-92-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-D1389. | |
| Sulfo-Cy5 amine | Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. Uses: Scientific research. Category: Signaling pathways. CAS No. 2183440-44-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-D1375. | |
| Sulfo-Cy5 azide | Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1782950-80-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145746. | |
| Sulfo-Cy5 carboxylic acid potassium | Sulfo-Cy5 carboxylic acid potassium is a water-soluble, inactive Cy5 carboxylic acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 1144107-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1374. | |
| Sulfo-Cy5-Mal | Sulfo-Cy5-Mal is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2130955-10-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-D1390A. | |
| Sulfo-Cy5-N3 | Sulfo-Cy5-N3 is a click chemistry reagent containing an azide group. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1481447-40-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-W400925. | |
| Sulfo-Cy7.5 NHS ester | Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2736437-44-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1568. | |
| Sulfo-Cyanine5.5 maleimide potassium | Sulfo-Cyanine5.5 maleimide (Sulfo-Cy5.5 maleimide) potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfo-Cy5.5 maleimide potassium. CAS No. 2183440-58-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1351. | |
| Sulfo DBCO-PEG4-amine | Sulfo DBCO-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055198-05-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140286. | |
| Sulfo-EGS | Sulfo-EGS is a homobifunctional, amine-reactive chemical crosslinker. Sulfo-EGS is used to study protein-protein or protein-peptide interactions, which can determine the spatial proximity of amino acid residues in a protein complex, without relying on standards[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 167410-92-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117080. | |
| Sulfo-NHS-Acetate | Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 152305-87-8. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-140341. | |
| Sulfo-NHS-Biotin sodium | Sulfo-NHS-Biotin sodium is a low-molecular-weight (MW 443.4 Da) tracer. Sulfo-NHS-Biotin sodium can used to assess blood-brain barrier permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 194041-65-1. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136964. | |
| Sulfo-NHS-LC-Biotin sodium | Sulfo-NHS-LC-Biotin sodium is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature. Uses: Scientific research. Category: Signaling pathways. CAS No. 191671-46-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0799. | |
| Sulfo-NHS-SS-Biotin sodium | Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 325143-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111496. | |
| Sulfopin | Sulfopin (PIN1-3) is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17 nM. Sulfopin blocks Myc-driven tumors in vivo. The peptidyl-prolyl isomerase, Pin1, is exploited in cancer to activate oncogenes and inactivate tumor suppressors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PIN1-3. CAS No. 2451481-08-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139361. | |
| Sulforaphane | Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission. Sulforaphane exhibits both anticancer and anti-inflammatory properties[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4478-93-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13755. | |
| Sulforhodamine B sodium salt | Sulforhodamine B sodium salt is a fluorescent dye with uses spanning from laser-induced fluorescence (LIF) to the quantification of cellular proteins of cultured cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acid Red 52; Kiton Red 620. CAS No. 3520-42-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g. Product ID: HY-D0974. | |
| Sulfo-SANPAH | Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker. Sulfo-SANPAH improves the functionalization process of PDMS surfaces, is covalently bound to the PAAm gel surface. Sulfo-SANPAH is widely used to crosslink ECM proteins to various substrates, including acrylic-based hydrogels, such as polyacrylamide hydrogels. Sulfo-SANPAH facilitates covalent binding through its negatively charged sulfonate group on its N-hydroxysuccinimide ester ring and a photoactivated phenyl azide group that is highly reactive with nucleophiles and free radicals[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102568-43-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-137383. | |
| Sulfo-SMCC sodium | Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 92921-24-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-D0975. | |
| sulfo-SPDB-DM4 | sulfo-SPDB-DM4 is a agent-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker. Uses: Scientific research. Category: Signaling pathways. CAS No. 1626359-59-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101141. | |
| Sulfo-TAG COOH trisodium | Sulfo-TAG COOH trisodium (Example 2) is a catalyst ligand that can be used for the synthesis of electrochemiluminescence (ECL) labels. Uses: Scientific research. Category: Signaling pathways. CAS No. 482618-43-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W697935. | |
| Sulfuretin | Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 120-05-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N1193. | |
| Sulindac | Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac also is an immunomodulatory agent. Sulindac can be used for the research of arthritis of the spine, gouty arthritis and kinds of cancer including colorectal cancer (CRC) and lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-231. CAS No. 38194-50-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0008. | |
| Sulodexide | Sulodexide is a mixture of glycosaminoglycans available in soft capsule form for oral administration. It is composed of low molecular weight heparin (80%) and dermatan sulfate (20%). Sulodexide exhibits antithrombotic activity through interaction with antithrombin III (AT III) and heparin cofactor II (HC II), and inhibition of thrombin formation. Sulodexide exhibits profibrinolytic activity through release of tissue plasminogen activator (tPA). Sulodexide exhibits endothelial protective and anti-inflammatory effect, ameliorates chronic venous disease[1].Sulodexide is a glycosaminoglycan mixture available in soft gelatin capsule form for oral administration. Uses: Scientific research. Category: Signaling pathways. CAS No. 57821-29-1. Pack Sizes: 250 LSU. Product ID: HY-100897. | |
| Sulodexide solution | Sulodexide solution is a mixture of glycosaminoglycans that can be administered by injection. It is composed of low molecular weight heparin (80%) and dermatan sulfate (20%). Sulodexide exhibits antithrombotic activity through interaction with antithrombin III (AT III) and heparin cofactor II (HC II), and inhibition of thrombin formation. Sulodexide exhibits profibrinolytic activity through release of tissue plasminogen activator (tPA). Sulodexide exhibits endothelial protective and anti-inflammatory effect, ameliorates chronic venous disease. Uses: Scientific research. Category: Signaling pathways. CAS No. 57821-29-1. Pack Sizes: 200 μL; 500 μL; 1 mL; 2 mL. Product ID: HY-100897A. | |
| Sulopenem | Sulopenem (CP-70429) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-70429. CAS No. 120788-07-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-105284. | |
| Sulpiride | Sulpiride is an orally active dopamine D2/D3 receptor antagonist. Sulpiride is an atypical antipsychotic agent of the benzamide family. Sulpiride can be used in research into anxiety, depression and breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15676-16-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1019. | |
| Sulprostone | Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHB 286; CP-34089; ZK-57671. CAS No. 60325-46-4. Pack Sizes: 1 mg (10.74 mM * 200 μL in Methyl acetate). Product ID: HY-19360. | |
| Sultiame | Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic agent. Uses: Scientific research. Category: Signaling pathways. CAS No. 61-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108316. | |
| Sumanirole maleate | Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. Sumanirole plays an important role in the research of Parkinson's disease and restless leg syndrome[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: U-95666E; PNU-95666. CAS No. 179386-44-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70081A. | |
| Sumatriptan | Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan can be used for migraine headache research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GR 43175 free base. CAS No. 103628-46-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-B0121B. | |
| SUMO Protease | SUMO Protease is highly specific for proteins containing small ubiquitin-like modifier (SUMO) tags. SUMO Protease can be used to regulates the proteins splicing, controlls protein structure and function in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1607459-82-4. Pack Sizes: 100 U; 500 U. Product ID: HY-E70372. | |
| SUN11602 | SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 704869-38-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101493. | |
| SUN B8155 | SUN B8155, a non-peptide agonist of calcitonin (CT) receptor, selectively mimics the biological actions of calcitonin. Calcitonin, a 32-amino acid peptide hormone secreted mainly from the thyroid gland, plays an important role in maintaining bone homeostasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 345893-91-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103302. | |
| Sunitinib | Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SU 11248. CAS No. 557795-19-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-10255A. | |
| Sunitinib Malate | Sunitinib (SU 11248) Malat is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib Malat, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SU 11248 Malate. CAS No. 341031-54-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-10255. | |
| Sunset Yellow FCF | Sunset Yellow FCF (Orange Yellow S) is an orange azo dye with a maximum absorption wavelength of 480 nm. Sunset Yellow FCF can be used in food, cosmetics and pharmaceuticals[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Orange Yellow S; Food Yellow 3; CI 15985. CAS No. 2783-94-0. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-D0249. | |
| Sunvozertinib | Sunvozertinib (DZD9008) is a potent ErbBs (EGFR, Her2, especially mutant forms) and BTK inhibitor. Sunvozertinib shows IC50s of 20.4, 20.4, 1.1, 7.5, and 80.4 nM for EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutations, and Her2 Exon20 YVMA, and EGFR WT A431, respectively (patent WO2019149164A1, example 52)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DZD9008. CAS No. 2370013-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-132842. | |
| SuO-Glu-Val-Cit-PAB-MMAE | SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NHS-Glutarate-Val-Cit-PAB-MMAE. CAS No. 1895916-24-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130989. | |
| Supercinnamaldehyde | Supercinnamaldehyde is a potent transient receptor potential ankyrin 1 (TRPA1) activator with an EC50 value of 0.8 μM. Supercinnamaldehyde activates TRPA1 ion channels through covalent modification of cysteines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 70351-51-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121539. | |
| Superoxide dismutase, Porcine erythrocytes | Superoxide dismutase, Porcine erythrocytes (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase, Porcine erythrocytes is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SOD. CAS No. 9054-89-1. Pack Sizes: 50 KU; 100 KU. Product ID: HY-129064. | |
| Super-TDU | Super-TDU is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU suppresses tumor growth in gastric cancer mouse model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599441-71-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1727. | |
| Supinoxin | Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase (P-p68) and a potent first-in-class anti-cancer agent. Supinoxin interacts with Y593 phosphorylated-p68 and attenuates the nuclear shuttling of β-catenin. Supinoxin induces cell apoptosis and inhibits growth of TNBC cancer cell lines with IC50s ranging from 10 nM to 20 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RX-5902. CAS No. 888478-45-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123611. | |
| Suramin sodium salt | Suramin sodium salt(Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor[1]. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM)[2]. Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM)[3][4]. Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor[5]. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent[6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Suramin hexasodium salt. CAS No. 129-46-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0879A. | |
| Suramin sodium salt (Standard) | Suramin (sodium salt) (Standard) is the analytical standard of Suramin (sodium salt). This product is intended for research and analytical applications. Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor[1]. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM)[2]. Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM)[3][4]. Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor[5]. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent[6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Suramin hexasodium salt (Standard). CAS No. 129-46-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0879AR. | |
| Surfactin | Surfactin is a potent cyclic lipopeptide biosurfactants consists of four isomers (Surfactin A, B, C and D), which mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects[1][2]. Surfactin also has antiviral activity against a variety of enveloped viruses[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 252023-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129555. | |
| Surfen dihydrochloride | Surfen dihydrochloride is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen dihydrochloride inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 μM. Surfen dihydrochloride inhibits HSV-1 viral infection. Surfen dihydrochloride inhibits neural differentiation, delays remyelination, and alleviates EAE[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aminoquinuride dihydrochloride. CAS No. 5424-37-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122704A. | |
| Surlorian | Surlorian is a ryanodine receptor (RyR) stabilizer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARM210. CAS No. 1467605-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159502. | |
| Surovatamig | Surovatamig (AZD0486; TNB-486) is a fully human anti-CD19/CD3 IgG4 bispecific antibody. Surovatamig triggers T cell activation, releases cytotoxic granules, and induces T cell-dependent cellular cytotoxicity and tumor cell lysis. Surovatamig can reduces release of pro-inflammatory cytokines including IL-2, IFNγ, TNF. Surovatamig can be used for the research of cancer, such as B cell non-Hodgkin lymphoma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD0486; TNB-486. CAS No. 2892667-02-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P991028. | |
| Survodutide | Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI 456906. CAS No. 2805997-46-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P4146. | |
| Sutezolid | Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PNU-100480; U-100480; PF-02341272. CAS No. 168828-58-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10392. | |
| Sutimlimab | Sutimlimab is a humanized monoclonal IgG4 antibody. Sutimlimab inhibits complement protein component 1, s subcomponent (C1s). Sutimlimab blocks C3 and C4 activation. Sutimlimab can be used for the research of cold agglutinin disease and complement-mediated hemolytic uremic syndrome[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIVV009; IPN-009; TNT009. CAS No. 2049079-64-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99050. | |
| Suvecaltamide | Suvecaltamide (MK-8998) is a selective T-type calcium channel inhibitor with oral efficacy. Suvecaltamide exhibits no cytotoxicity in myeloma cell lines and does not affect the antitumor efficacy of Bortezomib (BTZ). Suvecaltamide reverses BTZ-induced peripheral neuropathy (CIPN) in mouse and rat models, and helps inhibit myeloma growth[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-8998; CX-8998; JZP385. CAS No. 953778-58-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101096. | |
| Suvigletistat | Suvigletistat is a Transglutaminase 2 (TG2) inhibitor with an IC50 <0.5 μM. Suvigletistat can be used for the research of inflammatory disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2410912-75-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-177133. | |
| SUVN-911 | SUVN-911 is a potent, selective, brain penetrated and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist, with a Ki of 1.5 nM. SUVN-911 has antidepressant activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414674-71-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136146. | |
| Suvorexant impurity 1 | Suvorexant impurity 1 is an impurity of Suvorexant. Uses: Scientific research. Category: Signaling pathways. CAS No. 2941-79-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-78572. | |
| Suvratoxumab | Suvratoxumab (MEDI4893) is a long-acting, high-affinity human anti-α-toxin monoclonal antibody (IgG1κ type). Suvratoxumab potently neutralizes α-toxin, a key S. aureus virulence factor. Suvratoxumab improves survival and reduces lung injury in an immunocompromised mice model of pneumonia. Suvratoxumab also enhances the antibacterial activity of Vancomycin (HY-B0671) or Linezolid (HY-10394)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEDI4893. CAS No. 1629620-18-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99583. | |
| Suzetrigine | Suzetrigine (VX-548) is an orally active and highly selective NaV1.8 inhibitor that acts as an analgesic. Suzetrigine is also a blocker of sodium channel protein type 10 subunit alpha. Suzetrigine is promising for research of acute pain after abdominoplasty and bunionectomy[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-548. CAS No. 2649467-58-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-148800. | |
| Suzetrigine phenol | Suzetrigine phenol is the phenolate form of the sodium channel modulator Suzetrigine (HY-148800)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2649467-91-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160903. | |
| SV40 large T antigen NLS | SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. Uses: Scientific research. Category: Peptides. CAS No. 163815-24-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0310. | |
| (S)-Verapamil hydrochloride | (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-(-)-Verapamil hydrochloride. CAS No. 36622-28-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135336A. | |
| (S)-VU0637120 | (S)-VU0637120 is a Y4R antagonist that effectively reduces the binding response of its endogenous ligand, pancreatic polypeptide (PP), on Y4R, with an IC50 value of 2.7 μM. (S)-VU0637120 binds to the allosteric site of Y4R, which is located in the core region of the Y4R transmembrane structure, near the binding pocket of pancreatic polypeptide (PP), with a KB value of 300-400 nM. (S)-VU0637120 holds potential for research in the field of metabolic diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1175940-86-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-165125. | |
| SW016789 | SW016789 is a hypersecretion-inducer targeting VDAC1. SW016789 can induce insulin hypersecretion and Ca2+ influx in β-cells directly. SW016789 induces a transient endoplasmic reticulum stress response (ER stress), but does not cause beta cell death. SW016789 has reversible and non-apoptotic characteristics. SW016789 can be used for the study of Diabetes mellitus type 2 (T2DM) β-cell dysfunction[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 292613-04-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176745. | |
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