MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Val-Ala-PAB-MMAE | Val-Ala-PAB-MMAE is a Drug-Linker Conjugate for ADC, consisting of ADC linker (Val-Ala-PAB) and MMAE. MMAE is an effective inhibitor of tubulin. Uses: Scientific research. Category: Signaling pathways. CAS No. 1912408-92-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153032. |  |
| Valbenazine | Valbenazine (NBI-98854) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NBI-98854. CAS No. 1025504-45-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-16771. | |
| Val-Cit-PAB-Exatecan | Val-Cit-PAB-Exatecan (Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Val-Cit-PAB-DX8951. CAS No. 2227350-99-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153031. | |
| Val-Cit-PAB-MMAE | Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization. Uses: Scientific research. Category: Signaling pathways. CAS No. 644981-35-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100374. | |
| Valemetostat | Valemetostat (DS-3201), a first-in-class EZH1/2 dual inhibitor with IC50 values ?10 nM. Valemetostat can be used for the research of relapsed/refractory peripheral T-cell lymphoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS-3201. CAS No. 1809336-39-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109108. | |
| Valemetostat tosylate | Valemetostat (DS-3201) tosylate, a first-in-class EZH1/2 dual inhibitor with IC50 values ?10 nM. Valemetostat tosylate can be used for the research of relapsed/refractory peripheral T-cell lymphoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS-3201 tosylate. CAS No. 1809336-93-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109108A. | |
| Valepotriate | Valepotriate can be isolated from Valeriana jatamansi Jones, has anti-epileptic and anti-cancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Valtrate. CAS No. 18296-44-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0718. | |
| Valerate sodium | Valerate sodium is the sodium salt of valeric acid, a short-chain fatty acid, and exhibits oral activity. Valerate sodium reduces binge ethanol intake and decreases blood ethanol concentration in mice, while also exerting anxiolytic effects. Valerate sodium increases GABA levels, regulates epigenetics and alters gut microbiome function. Valerate sodium can be used in research related to excessive alcohol consumption[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6106-41-8. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g. Product ID: HY-W007087. | |
| Valerenic acid | Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABAA receptors. Valerenic acid is also a partial agonist of the 5-HT5a receptor. Valerenic acid mediates anxiolytic activity via GABAA receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Valerenic Acid. CAS No. 3569-10-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103524. | |
| Valerylcarnitine | Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Valerylcarnitine acts as a metabolomic biomarker for ionizing radiation exposure in nonhuman primates. Valerylcarnitine can be used for the research of type 1 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 40225-14-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113266. | |
| Valganciclovir hydrochloride | Valganciclovir hydrochloride is an orally active antiviral agent. Valganciclovir hydrochloride can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovir hydrochloride can be used for the research of Cytomegalovirus[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 175865-59-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-A0032A. | |
| Validamycin A | Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL[1]. Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM[2]. Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37248-47-8. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-B0856. | |
| Valilactone | Valilactone is a potent and effective inhibitor of esterase, produced by actinomycetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Valilactone. CAS No. 113276-96-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 500 μg. Product ID: HY-124258. | |
| Valiltramiprosate | ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated proagent of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound[1]. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimers disease[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALZ-801. CAS No. 1034190-08-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117259. | |
| Valinomycin | Valinomycin is a potassium-specific ionophore, the valinomycin-K+ complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K+ gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 122023. CAS No. 2001-95-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6693. | |
| Valiolamine | Valiolamine, an aminocyclitol, is an alpha-glucosidase inhibitor. Valiolamine has potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase. Valiolamine binds to porcine intestinal maltase and sucrase with Ki values of 350 nM and 30 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83465-22-9. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-131114. | |
| Valnoctamide | Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Valmethamide. CAS No. 4171-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121877. | |
| Valproic acid | Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM. Valproic acid inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VPA; 2-Propylpentanoic acid; Dipropylacetic acid. CAS No. 99-66-1. Pack Sizes: 500 mg; 1 g; 5 g; 25 g. Product ID: HY-10585. | |
| Valproic acid-d4-1 | Valproic acid-d4-1 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VPA-d4-1; 2-Propylpentanoic acid-d4-1. CAS No. 345909-03-7. Pack Sizes: 5 mg. Product ID: HY-10585S4. | |
| Valproic acid impurity 1 | Valproic acid impurity 1 is an impurity of Valproic acid (HY-10585). Uses: Scientific research. Category: Signaling pathways. CAS No. 5343-52-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-33358. | |
| Valproic acid sodium | Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium Valproate; VPA sodium; 2-Propylpentanoic acid sodium. CAS No. 1069-66-5. Pack Sizes: 500 mg; 1 g; 5 g; 25 g. Product ID: HY-10585A. | |
| Valrubicin | Valrubicin is a chemotherapy agent, inhibits TPA- and PDBu-induced PKC activation with IC50s of 0.85 and 1.25 μM, respectively, and has antitumor and antiinflammatory activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AD-32. CAS No. 56124-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13772. | |
| Valsartan | Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGP 48933. CAS No. 137862-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18204. | |
| Valsartan-d8 | Valsartan-d8 is the deuterium labeled Valsartan. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGP 48933-d8. CAS No. 1089736-72-0. Pack Sizes: 1 mg. Product ID: HY-18204S2. | |
| Valsartan (Standard) | Valsartan (Standard) is the analytical standard of Valsartan. This product is intended for research and analytical applications. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGP 48933 (Standard). CAS No. 137862-53-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18204R. | |
| Valspodar | Valspodar (PSC 833) is a selective P-glycoprotein inhibitor that has been used as an experimental cancer treatment and chemosensitizer. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PSC 833. CAS No. 121584-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17384. | |
| Vamikibart | Vamikibart (RG6179) is a monoclonal antibody targeting IL-6 that can be used to inhibit uveal macular edema (UME) and reduce retinal leakage. Vamikibart can reduce anterior chamber (AC) cell density, indicating a reduction in intraocular inflammation. Vamikibart can also be used to assess the leakage dynamics of ultra-wide-angle fluorescein angiography (UWFA) in the UME model to quantify changes in retinal leakage reflecting the effect of UME inhibition[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EBI-031. CAS No. 2744320-12-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990012. | |
| Vamorolone | Vamorolone (VBP15) is a first-in-class, orally active dissociative steroidal anti-inflammatory agent and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone shows potent NF-κB inhibition and substantially reduces hormonal effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VBP15. CAS No. 13209-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109017. | |
| Vancomycin | Vancomycin is an antibiotic for the treatment of bacterial infections. Uses: Scientific research. Category: Induced disease models products. CAS No. 1404-90-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-B0671. | |
| Vancomycin hydrochloride | Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis. Uses: Scientific research. Category: Signaling pathways. CAS No. 1404-93-9. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g; 5 g; 10 g. Product ID: HY-17362. | |
| Vancomycin hydrochloride (Standard) | Vancomycin (hydrochloride) (Standard) is the analytical standard of Vancomycin (hydrochloride). This product is intended for research and analytical applications. Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis. Uses: Scientific research. Category: Signaling pathways. CAS No. 1404-93-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17362R. | |
| Vancomycin (Standard) | Vancomycin (Standard) is the analytical standard of Vancomycin. This product is intended for research and analytical applications. Vancomycin is an antibiotic for the treatment of bacterial infections. Uses: Scientific research. Category: Signaling pathways. CAS No. 1404-90-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0671R. | |
| Vandetanib | Vandetanib (D6474) is a potent, orally active, and blood-brain-barrier penetrate inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZD6474. CAS No. 443913-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10260. | |
| Vandortuzumab vedotin | Vandortuzumab vedotin (DSTP 3086S; RG 7450) is a STEAP1-targeted antibody-drug conjugate (ADC). Vandortuzumab vedotin binds specifically to STEAP1, triggers internalization of the conjugate complex, mediates intracellular release of monomethyl auristatin E, inhibits cell division, and induces cell death. Vandortuzumab vedotin exhibits antitumor activity in preclinical prostate cancer xenografts. Vandortuzumab vedotin can be used for the research of metastatic castration-resistant prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DSTP 3086S; RG 7450; MSTP2109A. CAS No. 1471985-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99528. | |
| Vanillic acid glucoside | Vanillic acid glucoside (Vanillic acid 4-β-D-glucoside), a hydrolyzable tannin, is isolated from the fruits of C. annuum as well as the leaves of various additional plants. Vanillic acid glucoside can be phytotoxic against different species. Uses: Scientific research. Category: Natural products. Alternative Names: Vanillic acid 4-β-D-glucoside. CAS No. 32142-31-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114760. | |
| Vanillic acid (Standard) | Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 121-34-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0708R. | |
| Vanillin | Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Vanillin; m-Methoxy-p-hydroxybenzaldehyde; p-Hydroxy-m-methoxybenzaldehyde. CAS No. 121-33-5. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N0098. | |
| Vanillylamine | Vanillylamine is an immediate precursor for capsaicinoids. Vanillylamine is a derivative of Vanillin (HY-N0098) is synthesized through a transaminase reaction in the phenylpropanoid pathway of capsaicinoid synthesis. Vanillylamine significantly alleviates myelosuppression caused by abdominal and pelvic tumor chemotherapy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1196-92-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-W097899. | |
| Vanillylmandelic acid | Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55-10-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg. Product ID: HY-113121. | |
| Vanillylmandelic acid-d3 | Vanillylmandelic acid-d3 is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 74495-70-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg. Product ID: HY-113121S. | |
| Vanillylmandelic acid (Standard) | Vanillylmandelic acid (Standard) is the analytical standard of Vanillylmandelic acid. This product is intended for research and analytical applications. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55-10-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113121R. | |
| Vanilpyruvic acid | Vanilpyruvic acid is a catecholamine metabolite and precursor to vanillactic acid. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vanylpyruvic acid. CAS No. 1081-71-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101416. | |
| Vanoxerine dihydrochloride | Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) binds to the target site on the dopamine transporter (DAT)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GBR-12909 dihydrochloride; I893 dihydrochloride. CAS No. 67469-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13217. | |
| Vantictumab | Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OMP-18R5. CAS No. 1345009-45-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9974. | |
| Vanucizumab | Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human VEGFA Recombinant Antibody; RO5520985. CAS No. 1448221-05-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99330. | |
| Vanzacaftor | Vanzacaftor (VX-121) is an orally active noval corrector of Cystic fibrosis transmembrane conductance regulator (CFTR). Vanzacaftor improves processing and trafficking of CFTR protein as well as increases chloride transport in triple combined with Tezacaftor (HY-15448) and Deutivacaftor. Vanzacaftor-Tezacaftor-Deutivacaftor is safe and well tolerated, improving lung function, respiratory symptoms, and CFTR function with cystic fibrosis, which is promising for research in the field of cystic fibrosis diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-121. CAS No. 2374124-49-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 100 mg. Product ID: HY-145603. | |
| Vapendavir | Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BTA798. CAS No. 439085-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-106254. | |
| Vapendavir diphosphate | Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BTA798 diphosphate. CAS No. 1198151-75-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106254A. | |
| Vapitadine | Vapitadine is a non-sedative antihistamine compound that alleviates itching associated with atopic dermatitis. Uses: Scientific research. Category: Signaling pathways. CAS No. 793655-64-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14939. | |
| Vapreotide | Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC160; BMY 41606. CAS No. 103222-11-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0061. | |
| Vardenafil | Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4[1]. Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels[2]. Vardenafil can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 224785-90-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0442. | |
| Vardenafil hydrochloride | Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4[1]. Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels[2]. Vardenafil hydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 224785-91-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0442A. | |
| Varenicline | Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP 526555. CAS No. 249296-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10019. | |
| Varenicline Tartrate | Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP 526555-18. CAS No. 375815-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10021. | |
| Varespladib | Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY315920. CAS No. 172732-68-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13402. | |
| Varespladib methyl | Varespladib methyl (A-002; LY333013) is a selective inhibitor of group II secretory phospholipase A2 (PLA2). Uses: Scientific research. Category: Signaling pathways. Alternative Names: A-002; LY333013. CAS No. 172733-08-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17448. | |
| Varespladib sodium | Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY315920 sodium. CAS No. 172733-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13402A. | |
| Varlilumab | Varlilumab (CDX-1127) is an agonist anti-CD27 monoclonal antibody. Varlilumab can promote T cell expansion and activate the immune response. Varlilumab has anti-tumor activity and can be used in the research of hematological malignancies and solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CDX-1127. CAS No. 1393344-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99057. | |
| Varlitinib | Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASLAN001; ARRY-334543. CAS No. 845272-21-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10530. | |
| Varsetatug | Varsetatug (CX-2051 antibody) is a humanized IgG1κ monoclonal antibody inhibitor targeting EpCAM/TROP1/CD326. Varsetatug serves as the antibody component of the ADC compound CX-2051. It can be used in research on cancers including breast cancer, prostate cancer and ovarian cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CX-2051 antibody. CAS No. 3036004-28-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991723. | |
| VAS2870 | VAS2870 is a NADPH oxidase (NOX) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 722456-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12804. | |
| Vasculotide | Vasculotide is a blood-brain barrier (BBB)-penetrant Tie2 agonist. Vasculotide binds to a unique domain of Tie2, induces receptor clustering to drive phosphorylation, activates downstream PI3K/Akt and eNOS pathways, enhances inter-endothelial cell junctions (such as VE-cadherin and claudin-5), and inhibits inflammatory adhesion molecules, ultimately stabilizing the vascular endothelial barrier and reducing its permeability. Vasculotide alleviates pulmonary microvascular leakage and microcirculatory dysfunction caused by cardiopulmonary bypass, acts as an adjuvant radioprotective agent to reduce acute radiation dermatitis, and promotes BBB recovery after focused ultrasound (FUS). Combination of Vasculotide with antibiotics reduces lung injury[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1359657-45-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10580. | |
| Vasicine | Vasicine (peganine) is a quinazoline alkaloid isolated from Justicia adhatoda. Vasicine activates PI3K/Akt signaling pathway, exhibits antioxidant, anti-inflammatory and antibacterial activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Peganine. CAS No. 6159-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1103. | |
| Vasopressin | Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Arginine vasopressin; Antidiuretic hormone. CAS No. 11000-17-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1811. | |
| Vasopressin V2 receptor antagonist 2 | Vasopressin V2 receptor antagonist 2 (Compound 33) is an antagonist of the arginine vasopressin V2 receptor (V2R) with a Ki value of 6.2 nM. Vasopressin V2 receptor antagonist 2 can effectively reduce cAMP levels, thereby inhibiting the growth of renal cysts[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3057077-75-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162394. | |
| Vatalanib dihydrochloride | Vatalanib dihydrochloride (PTK787 dihydrochloride) is a BBB-permeable VEGFR2/KDR inhibitor with an IC50 of 37 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PTK787 dihydrochloride; ZK-222584 dihydrochloride; CGP-797870 dihydrochloride. CAS No. 212141-51-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12018. | |
| Vatinoxan hydrochloride | Vatinoxan hydrochloride (MK-467 hydrochloride;L-659066 hydrochloride) is a peripheral α2 adrenergic receptor antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-467 hydrochloride; L-659066 hydrochloride. CAS No. 130466-38-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19057A. | |
| VAV1 degrader-2 | VAV1 degrader-2 is a molecular glue degrader based on targeting Vav guanine nucleotide exchange factor 1 (VAV 1) with a DC50 of 4.41 nM. VAV1 degrader-2 can be used in the study of inflammatory and autoimmune diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3050683-29-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168624. | |
| VAV1 degrader-3 | VAV1 degrader-3 (Example 185) is an orally active VAV1 molecular glue degrader (DC50: 7 nM). VAV1 degrader-3 reduces immune cell activation, immune cell proliferation and the production of various cytokines. VAV1 degrader-3 can be used for research of inflammatory or autoimmune disorder. VAV1 degrader-3 inhibits disease progression in experimntal autoimmune encephalomyelitis (EAE) mouse model, Collagen-induced arthritis (CIA) mouse model, etc.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3050683-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168625. | |
| Vaxfectin | Vaxfectin is a second-generation cationic lipid-based suspension that adjuvants effectively both pDNA and protein-based vaccines. Vaxfectin can boost the immune response against a range of pDNA-expressed pathogenic antigens in vivo. Vaxfectin can increase IgG titers and give rise to an IL-6 dependent enhancement of the humoral immune response without altering the Th1 type immune response. Vaxfectin can be studied for vaccine formulation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 370108-99-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-142998. | |
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