MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| AZP-531 | AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. Uses: Scientific research. Category: Signaling pathways. CAS No. 1088543-62-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0231. |  |
| AZ PFKFB3 26 | AZ PFKFB3 26 is a potent and selective PFKFB3 inhibitor with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively. AZ PFKFB3 26 can be used in the study of non-small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1704740-52-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101971. | |
| AZ-PFKFB3-67 | AZ-PFKFB3-67 is a potent and selective PFKFB3 kinase inhibitor with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1, respectively. AZ-PFKFB3-67 reduces MCL-1. AZ-PFKFB3-67 has neuroprotective activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1704741-11-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101972. | |
| Aztreonam | Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3). Uses: Scientific research. Category: Signaling pathways. Alternative Names: SQ-26,776. CAS No. 78110-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-B0129. | |
| Aztreonam (Standard) | Aztreonam (Standard) is the analytical standard of Aztreonam. This product is intended for research and analytical applications. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3). Uses: Scientific research. Category: Signaling pathways. Alternative Names: SQ-26,776 (Standard). CAS No. 78110-38-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0129R. | |
| AZT triphosphate tetraammonium | AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) tetraammonium is an active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate tetraammonium exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate tetraammonium also inhibits the DNA polymerase of HBV. AZT triphosphate tetraammonium activates the mitochondria-mediated apoptosis pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3'-Azido-3'-deoxythymidine-5'-triphosphate tetraammonium. CAS No. 106060-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116364B. | |
| Azukisaponin II | Azukisaponin II is a natural saponin. Azukisaponin II has anti-herpes virus activity and antioxidant activity[1]. Uses: Scientific research. Category: Natural products. CAS No. 82793-03-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N13145. | |
| Azure B | Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Azure B chloride. CAS No. 531-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D0004. | |
| Azvudine | Azvudine (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM). Azvudine inhibits NRTI-resistant viral strains[1]. Azvudine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO-0622; FNC. CAS No. 1011529-10-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19314. | |
| Azvudine hydrochloride | Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM). Azvudine hydrochloride inhibits NRTI-resistant viral strains[1]. Azvudine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO-0622 hydrochloride; FNC hydrochloride. CAS No. 1333126-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19314A. | |
| B022 | B022 is a potent and selective NF-κB-inducing kinase (NIK) inhibitor (Ki of 4.2 nM; IC50=15.1 nM). B022 protects liver from toxin-induced inflammation, oxidative stress, and injury[1][2]. B022 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1202764-53-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120501. | |
| B32B3 | B32B3 is an inhibitor of VprBP with an IC50 value of 0.5 μM at the H2AT120p cell. B32B3 can suppress tumor growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 294193-86-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12240. | |
| B-355252 | B355252, a phenoxy thiophene sulfonamide small molecule, is a potent NGF receptor agonist. B355252 potentiates NGF-induced neurite outgrowth. B355252 protects ischemic neurons from neuronal loss by attenuating DNA damage, reducing ROS production and the LDH level, and preventing neuronal apoptosis. B355252 has anti-apoptotic effects in glutamate-induced excitotoxicity, as well as in a murine hippocampal cell line (HT22) model of Parkinson disease (PD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1261576-81-1. Pack Sizes: 5 mg. Product ID: HY-120553. | |
| B3GNT2-IN-1 | B3GNT2-IN-1 (compound 8j) is a β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) inhibitor, with an IC50 of 9 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033557-95-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149777. | |
| B8R 20-27 | B8R 20-27 is a biological active peptide. (This is amino acids 20 to 27 fragment of B8R, a vaccinia virus (VV) gene that encodes a secreted protein related to gamma interferon receptor. B8R binding to IFN-g neutralizes its antiviral activity.). Uses: Scientific research. Category: Peptides. CAS No. 848642-31-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5364. | |
| BA-53038B | BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly. BA-53038B has antiviral activity for hepatitis B virus (HBV) with an EC50 value of 3.32 μM. BA-53038B can be used for the research of chronic hepatitis B[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2306195-65-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114314. | |
| BAA473 | BAA473 is a bile acid analog and is a potent activator of the pyrin inflammasome that induces the secretion of interleukin 18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 27240-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123879. | |
| Baccatin III | Baccatin III is an orally available, selective inhibitor of the TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation. Baccatin III targets the AKT/STAT6 and Smad2/3 pathways, blocking TGF-β1-induced fibroblast differentiation and MDSC-mediated immunosuppression. Baccatin III exerts anti-inflammatory and anti-fibrotic effects by inhibiting macrophage activation and extracellular matrix deposition, and shows potential in the treatment of pulmonary fibrosis and cancer in terms of regulating the tumor immune microenvironment[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 27548-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N6985. | |
| BACE2-IN-1 | BACE2-IN-1 (compound 3l) is a highly selective BACE2 inhibitor with a Ki value of 1.6 nM. BACE2 inhibitors can be used to research of Type 2 Diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1676107-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-136742. | |
| Bacillibactin | Bacillibactin (Corynebactin) is a cyclic tricatecholate siderophore. Bacillibactins primary function is to facilitate bacterial iron acquisition by chelating iron ions (Fe3+) from the environment, thereby aiding bacterial survival under iron-limited conditions. Bacillibactin exhibits direct antimicrobial activity, such as inhibition of the growth of the producing bacteria Pseudomonas aeruginosa and Aeromonas veronae, as well as plant pathogens such as Pseudomonas syringae.Bacillibactin can be used in antibacterial and antifungal research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Corynebactin. CAS No. 95536-41-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-160238. | |
| Bacitracin | Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1405-87-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-107193. | |
| Bacitracin A | Bacitracin A is an antibiotic, which exhibits antibacterial activity against gram-positive bacteria. Bacitracin A forms complex with long-chain polyisoprenyl pyrophosphates in presence of metal ions, dephosphorylates the lipid carrier intermediate Css-bactoprenyl pyrophosphate, inhibits thus the bacterial cell wall biosynthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22601-59-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W587753. | |
| Baclofen | Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist with blood-brain barrier permeability. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1134-47-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0007. | |
| Bacopasaponin C | Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC50 of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 178064-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N6015. | |
| Bacopaside II | Bacopaside II, an extract from the medicinal herb Bacopa monnieri. Bacopaside II is the inhibitor for AQP1 that exhibits anti-angiogenesis activity. Bacopaside II exhibits cytotoxicity and induces apoptosis in cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 382146-66-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6016. | |
| Bacoside A3 | Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 157408-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N5064. | |
| Bacterial α-Amylase | Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9000-85-5. Pack Sizes: 10 g. Product ID: HY-P2968. | |
| BAD (103-127) (human) | BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL. BAD (103-127) (human) is reported to have almost 800-fold higher affinity for Bcl-XL than the 16-mer peptide[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BADBH3 103-127 (human); BADBH3 (human). CAS No. 331762-68-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2468. | |
| Bafetinib | Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INNO-406; NS-187. CAS No. 859212-16-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50868. | |
| Bafilomycin A1 | Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BafA1. CAS No. 88899-55-2. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-100558. | |
| Bafilomycin B1 | Bafilomycin B1 is a macrolide antibiotic that can be isolated from mycelium of Streptomyces gresuis. Bafilomycin B1 is neuroprotective against Chloroquine (HY-17589A)-induced death. Bafilomycin B1 is a structural analog of Bafilomycin A1 and has the ability to inhibit V-ATPase. Bafilomycin B1 inhibits significantly the oxidized low density lipoprotein (LDL)-induced accumulation of lipid droplets[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 88899-56-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6738. | |
| Bafilomycin C1 | Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi[2]. Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 88979-61-7. Pack Sizes: 1 mg. Product ID: HY-130173. | |
| BAI1 | BAI1 is a selective and allosteric inhibitor of BAX, an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX-dependent cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 335165-68-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103269. | |
| BAI1 hydrochloride | BAI1 hydrochloride is a selective apoptosis factor BAX allosteric inhibitors. BAI1 hydrochloride binds BAX and allosterically inhibits its activation. BAI1 hydrochloride has the potential to be used in the study of BAX dependent cell death-mediated diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329349-20-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-110031. | |
| Baicalein | Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,6,7-Trihydroxyflavone. CAS No. 491-67-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0196. | |
| Baicalin | Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Baicalein 7-O-β-D-glucuronide. CAS No. 21967-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0197. | |
| Bakuchiol | Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) [2] and human carboxylesterase 2 (hCE2) [3], with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory[5], antibacterial[4], antitumor[1] therapies, as well as drug metabolism regulation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-(+)-Bakuchiol. CAS No. 10309-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0235. | |
| BAL-0028 | BAL-0028 is a reversible inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with KD values of 104-123 nM. BAL-0028 can inhibit the secretion of IL-1β and has anti-inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2842012-69-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162333. | |
| BAL-30072 | BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 941285-15-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19882. | |
| Balaglitazone | Balaglitazone is a selective partial PPARγ agonist with an EC50 of 1.351 μM for human PPARγ. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DRF 2593; NN 2344. CAS No. 199113-98-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16086. | |
| Balamapimod | Balamapimod (MKI 833) is a reversible Ras/Raf/MEK inhibitor with potential anti-tumor activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MKI 833. CAS No. 863029-99-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-14947. | |
| Balicatib | Balicatib (AAE581) is a potent, orally active and selective cathepsin K inhibitor with IC50 values of 22, 61, 48, 2900 nM for cathepsin K, cathepsin B, cathepsin L, cathepsin S, respectively. Balicatib inhibits bone turnover, decreases bone formation rates. Balicatib has the potential for the research of osteoporosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AAE581. CAS No. 354813-19-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15100. | |
| Baliforsen | Baliforsen (ISIS 5987690) is an antisense oligonucleotide (ASO) that inhibits DMPK mRNA. Baliforsen binds within exon 9 of the human DMPK transcript to promote RNase H1-mediated degradation Baliforsen can be used for the research of myotonic dystrophy type 1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS 598769; IONIS 598769; BIIB 065; ISIS-DMPK-2.5Rx. CAS No. 1698048-23-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145725A. | |
| Baliforsen sodium | Baliforsen (sodium) is an antisense oligonucleotide (16 nucleotides) designed to target myotonic dystrophy protein kinase (DMPK) mRNA and research myotonic dystrophy. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IONIS 598769 sodium; ISIS 598769 sodium. CAS No. 1687746-79-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145725. | |
| Balinatunfib | Balinatunfib (SAR-441566) is an orally active inhibitor of TNFR1 signaling. By binding to the central pocket of the soluble TNFα (sTNFα) trimer, Balinatunfib stabilizes an asymmetric conformation, blocking its binding to TNFR1 (without affecting TNFR2) and thus inhibiting downstream pathways. Balinatunfib has anti-inflammatory activity, and can be used in the study of autoimmune diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR-441566; TNFα activity modulator 3. CAS No. 2248726-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160412. | |
| Balipodect | Balipodect (TAK-063) is a selective, brain-penetrant and orally active PDE10A inhibitor with an IC50 of 0.30 nM. Balipodect shows >15000-fold selectivity over other PDEs. Balipodect elevates striatal cAMP and cGMP levels in mice. Balipodect can be used for the study of schizophrenia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-063. CAS No. 1238697-26-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12472. | |
| Balixafortide | Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: POL6326. CAS No. 1051366-32-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1682. | |
| Balomenib | Balomenib (ZE63-0302) is an orally bioavailable menin-KMT2A interaction inhibitor. Balomenib disrupts menin-KMT2A binding, reverses aberrant HOX gene expression. Balomenib inhibits Meis1 mRNA expression in KMT2A-rearranged acute myeloid leukemia cells. Balomenib can be used for the research of leukemia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZE63-0302. CAS No. 2939850-17-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-172416. | |
| Balovaptan | Balovaptan (RG7314) is an orally available, selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG7314. CAS No. 1228088-30-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109024. | |
| Baloxavir | Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Baloxavir acid; S-033447. CAS No. 1985605-59-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109025A. | |
| Baloxavir marboxil | Baloxavir marboxil (S-033188) is a selective inhibitor of influenza cap-dependent endonuclease. Baloxavir marboxil, a potent antiviral agent, shows activity against influenza A and B virus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-033188; RG 6152. CAS No. 1985606-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-109025. | |
| Balstilimab | Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AGEN2034. CAS No. 2148321-77-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99457. | |
| BAM 15 | BAM 15 is a mitochondrial protonophore uncoupler. BAM 15 is an oxidative phosphorylation (OXPHOS) uncoupler[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210302-17-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-110284. | |
| BAM7 | BAM7 is a direct and selective activator of proapoptotic BAX with an IC50 of 3.3 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 331244-89-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15341. | |
| BAM(8-22) | BAM(8-22), a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor (SNSR) agonist, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1. BAM(8-22) induces scratching in mice in an Mrgpr-dependent manner. In addition, BAM(8-22) has an analgesic effect and can also inhibit the activation of microglia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 412961-36-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1241. | |
| Bamadutide | Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor (GLP-1R/GCGR) agonist. Bamadutide improves post-meal blood glucose control by significantly enhancing β-cell function and slowing down the rate of glucose absorption in the body. Bamadutide can be used for the research of metabolic diseases such as type 2 diabetes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR425899. CAS No. 1596343-09-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10018. | |
| BAMEA-O16B | BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2490668-30-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-139306. | |
| Baminercept | Baminercept (BG 9924; TT-47) is an Ig fusion protein targeting the lymphotoxin β receptor (LTβR). Baminercept effectively regulates subsets of circulating immune cells by inhibiting LIGHT, LT-α1β2 and their receptors. Baminercept also increases blood lymphocyte counts and reduces plasma CXCL13 levels. Baminercept carries a high risk of hepatotoxicity. Baminercept can be used in research on rheumatoid arthritis and primary Sjögren's syndrome[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BG 9924; TT-47. CAS No. 909110-25-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99459. | |
| Bamlanivimab | Bamlanivimab (Anti-Human SARS-CoV-2) is the first COVID-19 monoclonal antibody (mAb) to be granted Emergency Use Authorization (EUA) in November 2020 by the U.S. Food and agent Administration (FDA). However, Bamlanivimab is withdrawn in April 2021 following the rise of SARS-CoV-2 virus variants resistant to Bamlanivimab[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human SARS-CoV-2. CAS No. 2423943-37-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99344. | |
| Bamocaftor | Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore F508del-CFTR protein function. Bamocaftor can be used combine with Tezacaftor (HY-15448) and Ivacaftor (HY-13017) in cystic fibrosis research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-659. CAS No. 2204245-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126394. | |
| Banoxantrone dihydrochloride | Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AQ4N dihydrochloride. CAS No. 252979-56-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13562A. | |
| Baohuoside I | Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Icariin-II; Icariside-II. CAS No. 113558-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0011. | |
| b-AP15 | b-AP15 is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 687852. CAS No. 1009817-63-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13989. | |
| BAP1-IN-1 | BAP1-IN-1 (Compound 8) is a BRCA1 associated protein 1 (BAP1) catalytic activity inhibitor with an IC50 of 0.1-1 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 353495-21-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W327122. | |
| Bapineuzumab | Bapineuzumab is an anti-β-amyloid protein (APP) monoclonal antibody. Bapineuzumab is a humanized IgG1 that recognizes the N terminus of Aβ cleared plaques from the brains. Bapineuzumab can be used for the research of Alzheimers disease (AD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AAB-001. CAS No. 648895-38-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99185. | |
| Bapotulimab | Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: BAY-1905254. CAS No. 2359413-58-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99460. | |
| BAPTA | BAPTA is a selective and cell-impermeant chelator for calcium. BAPTA has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 85233-19-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-100168. | |
| BAPTA-AM | BAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 126150-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100545. | |
| BAPTA tetrapotassium | BAPTA tetrapotassium is a selective and cell-impermeant chelator for calcium. BAPTA has high selectivity against magnesium and calcium. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73630-08-7. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 250 mg. Product ID: HY-100168B. | |
| BAPTA tetrasodium | BAPTA tetrasodium is a selective and cell-impermeant chelator for calcium. BAPTA tetrasodium has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 126824-24-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-100168A. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.