Selleck Chemicals - Products
United States; Europe
Selleck Chemicals supplies bioactive small molecules, inhibitors, compound libraries, antibodies, natural products and related research reagents for life science research.
| Product | Description | |
|---|---|---|
| xCT/SLC7A11 Antibody [E20L8] | xCT,xCT/SLC7A11. Group: Antibodies. Alternative Names: xCT,SLC7A11. CAS No. Pack Sizes: 20ul. Product ID: F0517. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| xCT/SLC7A11 Antibody [H13H3] | xCT,xCT/SLC7A11. Group: Antibodies. Alternative Names: Cystine / glutamate transporter, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Solute carrier family 7 member 11, SLC7A11. CAS No. Pack Sizes: 20uL. Product ID: F3380. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| XMU-MP-1 | XMU-MP-1 is an inhibitor of MST1/2 with IC50 values of 71.1±12.9 nM and 38.1±6.9 nM against MST1 and MST2, respectively. Group: Inhibitors. CAS No. 2061980-01-4. Pack Sizes: 2mg. Product ID: S8334. Formula: C17H16N6O3S2. Smiles: CN1C2=C(C(=O)N(C3=CN=C(N=C31)NC4=CC=C(C=C4)S(=O)(=O)N)C)SC=C2. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Y-27632 | Y-27632 is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. Group: Inhibitors. CAS No. 146986-50-7. Pack Sizes: 5mg. Product ID: S6390. Formula: C14H21N3O. Smiles: CC(N)C1CCC(CC1)C(=O)NC2=CC=NC=C2. Storage Conditions: 3 years -20°C powder? 2 years -80°C in solvent. | United States; Europe |
| Y-27632 Dihydrochloride | Y-27632 2HCl is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. Group: Inhibitors. CAS No. 129830-38-2. Pack Sizes: 2mg. Product ID: S1049. Formula: C14H21N3O.2HCl. Smiles: CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl. Storage Conditions: 3 years-20°C powder. | United States; Europe |
| YAP Antibody [C6K11] | YAP,YAP1. Group: Antibodies. Alternative Names: YAP,YAP1. Pack Sizes: 20uL. Product ID: F0366. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| YAP-TEAD Inhibitor 1 (Peptide 17) | YAP-TEAD Inhibitor 1 (Peptide 17) is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM. Group: Inhibitors. CAS No. 1659305-78-8. Pack Sizes: 1mg. Product ID: S8164. Formula: C93H144ClN23O21S2. Smiles: CCCCC1NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(CCSSCC(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(C)NC(=O)C3CCCN3C1=O)C(=O)NC(CCCCN)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(CCC(O)=O)C(N)=O)NC(=O)C(C. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| YC-1 (Lificiguat) | Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). Group: Inhibitors. CAS No. 170632-47-0. Pack Sizes: 10mg. Product ID: S7958. Formula: C19H16N2O2. Smiles: C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)C4=CC=C(O4)CO. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Yoda1 | Yoda1 acts as an agonist for both human and mouse Piezo1(EC50 of 17.1 and 26.6 μM for mouse and human). Yoda1 activates purified Piezo1 channels in the absence of other cellular components. Group: Inhibitors. CAS No. 448947-81-7. Pack Sizes: 5mg. Product ID: S6678. Formula: C13H8Cl2N4S2. Smiles: C1=CC(=C(C(=C1)Cl)CSC2=NN=C(S2)C3=NC=CN=C3)Cl. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| (Z)-4-Hydroxytamoxifen | (Z)-4-Hydroxytamoxifen ((Z)-4-OHT, trans-4-Hydroxytamoxifen, 4-Monohydroxytamoxifen) is a selective modulator of estrogen receptor (SERM) with IC50 of 3.3 nM for the [3H]oestradiol binding to oestrogen receptor. Group: Inhibitors. Alternative Names: (Z)-4-OHT, trans-4-Hydroxytamoxifen, 4-Monohydroxytamoxifen. CAS No. 68047-06-3. Pack Sizes: 5mg. Product ID: S8956. Formula: C26H29NO2. Smiles: CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Z-DEVD-FMK | Z-DEVD-FMK (Caspase-3 Inhibitor) is a specific, irreversible Caspase-3 inhibitor, and also shows potent inhibition on caspase-6, caspase-7, caspase-8, and caspase-10. Group: Inhibitors. Alternative Names: Caspase-3 Inhibitor. CAS No. 210344-95-9. Pack Sizes: 1mg. Product ID: S7312. Formula: C30H41FN4O12. Smiles: CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(CC(=O)OC)NC(=O)OCC1=CC=CC=C1. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Z-IETD-FMK | Z-IETD-FMK (Caspase-8 Inhibitor, Z-IE(OMe)TD(OMe)-FMK) is a specific Caspase-8 inhibitor. Z-IETD-FMK is also an inhibitor of granzyme B. Group: Inhibitors. Alternative Names: Caspase-8 Inhibitor, Z-IE(OMe)TD(OMe)-FMK. CAS No. 210344-98-2. Pack Sizes: 1mg. Product ID: S7314. Formula: C30H43FN4O11. Smiles: CCC(C)C(C(=O)NC(CCC(=O)OC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Ziftomenib (KO-539) | Ziftomenib (KO-539) is an oral inhibitor of menin targeting the menin-KMT2A protein-protein interaction. It exhibits antileukemic activity and induces apoptosis of acute myeloid leukemia(AML) cells. Group: Inhibitors. Alternative Names: KO-539. CAS No. 2134675-36-6. Pack Sizes: 1mg. Product ID: E1290. Formula: C33H42F3N9O2S2. | United States; Europe |
| Z-LEHD-FMK TFA | Z-LEHD-FMK TFA (Caspase-9 Inhibitor) is a cell-permeable, competitive and irreversible inhibitor of enzyme caspase-9, which helps in cell survival. Group: Inhibitors. Alternative Names: Caspase-9 Inhibitor. CAS No. 524746-03-0. Pack Sizes: 2mg. Product ID: S7313. Formula: C34H44F4N6O12. Smiles: CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2.C(=O)(C(F)(F)F)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| ZM 447439 | ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc. Group: Inhibitors. CAS No. 331771-20-1. Pack Sizes: 5mg. Product ID: S1103. Formula: C29H31N5O4. Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| ZO1 tight junction protein Antibody [A24G22] | Tight Junction Protein 1,ZO-1,ZO1 tight junction protein. Group: Antibodies. Alternative Names: ZO1; TJP1; Tight junction protein ZO-1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1. Pack Sizes: 20uL. Product ID: F2530. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| ZO1 tight junction protein Antibody [K13A12] | Tight Junction Protein 1,ZO-1,ZO1 tight junction protein. Group: Antibodies. Alternative Names: Tight Junction Protein 1,ZO-1,ZO1 tight junction protein. Pack Sizes: 20ul. Product ID: F0065. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Zoldonrasib (RMC-9805) | Zoldonrasib (RMC-9805) is an orally active inhibitor of KRAS G12D. RMC-9805 inhibits RAS signaling, leading to apoptosis in cancer cells with the KRAS G12D mutation. Group: Inhibitors. Alternative Names: KRAS G12D ON inhibitor. CAS No. 2922732-54-3. Pack Sizes: 1mg. Product ID: E1962. Formula: C63H88F3N11O7. | United States; Europe |
| Zoledronic acid (Zoledronate) | Zoledronic acid (Zoledronate), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy. Group: Inhibitors. Alternative Names: ZA, CGP-4244, GP42446A, ZOL 446. CAS No. 118072-93-8. Pack Sizes: 25mg. Product ID: S1314. Formula: C5H10N2O7P2. Smiles: C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Z-VAD-FMK | Z-VAD-FMK (Z-VAD(OMe)-FMK) is a cell-permeable, irreversible pan-caspase inhibitor, blocks all features of apoptosis in THP.1 and Jurkat T-cells. Group: Inhibitors. Alternative Names: Z-VAD(OMe)-FMK. CAS No. 187389-52-2. Pack Sizes: 5mg. Product ID: S7023. Formula: C22H30FN3O7. Smiles: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
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