BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CDK7-IN-1 | CDK7-IN-1 is an analog of YKL-5-124 and a CDK7 inhibitor with an IC50 of less than 100 nM. (Extracted from patent WO 2016105528 A2, Compound 215). Synonyms: Pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide, N-[(1S)-2-(dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxopropyl)amino]benzoyl]amino]-. Grade: ≥98%. CAS No. 1957203-02-9. Molecular formula: C28H35N7O3. Mole weight: 517.62. |  |
| CDK7-IN-10 | CDK7-IN-10 is a CDK7 inhibitor with an IC50 of <100 nM, and has the potential to inhibit cell growth and induce apoptosis. (Extracted from patent WO2021016388A1, compound I-1). Synonyms: Pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide, N-[(1S)-2-(dimethylamino)-1-phenylethyl]-4,6-dihydro-1,6,6-trimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]-. CAS No. 2588110-62-5. Molecular formula: C29H35N7O3. Mole weight: 529.63. | |
| CDK7-IN-2 hydrochloride hydrate | CDK7-IN-2 hydrochloride hydrate is a potent and selective CDK7 inhibitor with potent anticancer activity. Synonyms: (S,E)-1-(4-(dimethylamino)but-2-enoyl)pyrrolidin-3-yl 4-((3-isopropyl-5-methylpyrazolo[1,5-a]pyrimidin-7-yl)amino)piperidine-1-carboxylate hydrochloride hydrate. CAS No. 2326428-24-2. Molecular formula: C26H42ClN7O4. Mole weight: 552.11. | |
| CDK7-IN-5 | CDK7-IN-5, a CDK7 inhibitor with an IC50 of <100 nM, has anticancer effects. (Extracted from patent WO2015154022A1, Compound 104). Synonyms: 2-Butenamide, 4-(dimethylamino)-N-[4-[[[2-[[[8-(1-methylethyl)-2-[(1-methyl-4-piperidinyl)oxy]pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]amino]methyl]phenyl]-, (2E)-; (E)-4-(dimethylamino)-N-(4-(((2-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)amino)methyl)phenyl)but-2-enamide. CAS No. 1817006-50-0. Molecular formula: C34H45N9O2. Mole weight: 611.78. | |
| CDK7-IN-6 | CDK7-IN-6 is a potent and selective CDK7 inhibitor (IC50 ≤100 nM) that can be used in cancer research. CDK7-IN-6 shows >200-fold selectivity for CDK7 over CDK1, CDK2, and CDK5. (Extracted from patent WO2019197549 A1, compound 210). Synonyms: 1H-Pyrazole-3-methanol, 1-[2-[[[2-(4-amino-1-piperidinyl)-8-(1-methylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]-3-chlorophenyl]-α,α-dimethyl-. CAS No. 2378710-04-2. Molecular formula: C26H34ClN9O. Mole weight: 524.06. | |
| CDK7-IN-7 | CDK7-IN-7 is a potent and selective inhibitor of CDK7 kinase with an IC50 of <50 nM. (Patent CN112661745A, compound T-01). Synonyms: methyl (S)-(7-bromo-3-(2-(piperidin-3-ylamino)-5-(trifluoromethyl)pyrimidin-4-yl)-1H-indol-6-yl)carbamate. CAS No. 2640208-01-9. Molecular formula: C20H20BrF3N6O2. Mole weight: 513.31. | |
| CDK8-IN-4 | CDK8-IN-4 is a CDK8 inhibitor with an IC50 of 0.2 nM. (Extracted from patent WO2014090692A1, compound example 16). Synonyms: (2R)-2-{[5-(1H-Indazol-5-yl)-3-pyridinyl]amino}-2-phenylethanol; (R)-2-((5-(1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylethan-1-ol; Benzeneethanol, β-[[5-(1H-indazol-5-yl)-3-pyridinyl]amino]-, (βR)-. Grade: ≥97%. CAS No. 1613638-82-6. Molecular formula: C20H18N4O. Mole weight: 330.38. | |
| CDK9-IN-1 | Among CDKs, CDK9 is a validated pathological target in HIV infection, inflammation and cardiac hypertrophy; however selective CDK9 inhibitors are still not available. We present a selective inhibitor family of CDK9 based on the 4-phenylamino-6- phenylpyrimidine nucleus. We show a convenient synthetic method to prepare a useful intermediate and its derivatisation resulting in novel compounds. The CDK9 inhibitory activity of the derivatives was measured in specific kinase assay and the CDK inhibitory profile of the best ones (IC50 > 100nM) was determined. The most selective compounds had high selectivity over CDK1, 2, 3, 5, 6, 7 and showed at least one order of magnitude higher inhibitory activity over CDK4 inhibition. The most selective molecules were examined in cytotoxicity assays and their ability to inhibit HIV-1 replication was determined in cellular assays. Synonyms: CDK9-IN-1; CDK9 IN 1. Grade: >98%. CAS No. 1415559-43-1. Molecular formula: C26H21N5O4S. Mole weight: 499.54. | |
| CDK9-IN-10 | CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for PROTAC CDK9 degrader-2. Synonyms: 7-benzyloxy-5,8-dihydroxyflavone; 4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)-; 7-(Benzyloxy)-5,8-dihydroxy-2-phenyl-4H-chromen-4-one. Grade: ≥95%. CAS No. 3542-63-0. Molecular formula: C22H16O5. Mole weight: 360.36. | |
| CDK9-IN-11 | CDK9-IN-11 is a potent CDK9 inhibitor and ligand of PROTAC CDK9 Degrader-1. Synonyms: 2-Methyl-2-propanyl 5-cyclobutyl-3-{[(4-hydroxyphenyl)acetyl]amino}-1H-pyrazole-1-carboxylate; 1H-Pyrazole-1-carboxylic acid, 5-cyclobutyl-3-[[2-(4-hydroxyphenyl)acetyl]amino]-, 1,1-dimethylethyl ester. Molecular formula: C20H25N3O4. Mole weight: 371.43. | |
| CDK9-IN-12 | CDK9-IN-12 shows the optimal inhibitory activity of CDK9 with an IC50 of 5.41 nM. Synonyms: Benzeneethanol, β-[[6-chloro-5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]amino]-, (βR)-. CAS No. 1942843-54-0. Molecular formula: C21H19ClN4O. Mole weight: 378.85. | |
| CDK9-IN-2 | CDK9-IN-2 is a novel cyclin-dependent kinase 9(CDK9) inhibitor. Synonyms: CDK9 Inhibitor II; CDK9 Inhibitor 2; CDK9-In-2; CDK9-IN2. Grade: >98%. CAS No. 1263369-28-3. Molecular formula: C23H25ClFN5. Mole weight: 425.93. | |
| CDK9-IN-28 | CDK9-IN-28 is a CDK9-targeting ATTEC (Autophagosome-tethering compound). CDK9-IN-28, an effective CDK9 inhibitor, can be used as a PROTAC target protein ligand for PROTAC synthesis and has shown strong anti-proliferative activity in solid tumors. This indicates that CDK9-IN-28 has the ability to degrade specific proteins through the autophagy pathway, which is consistent with the characteristics of ATTEC technology. Synonyms: 4-Piperidinecarboxamide, N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-1-[5-[(7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-5-yl)oxy]pentyl]-; N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(5-((7-hydroxy-4-methyl-2-oxo-2H-chromen-5-yl)oxy)pentyl)piperidine-4-carboxamide; CDK3-LC3B-10. Grade: ≥95%. CAS No. 3020773-81-0. Molecular formula: C32H40N4O6S2. Mole weight: 640.81. | |
| CDK9-IN-6 | CDK9-IN-6, one of the CDK9 inhibitors, probably have potential activity in influencing cell cycle of T-type cells. Uses: Cdk9-in-6 is one of the cdk9 inhibitors that probably have potential activity in influencing cell cycle of t-type cells. Synonyms: CDK9-IN-6; SCHEMBL12466375; SCHEMBL15378321; SCHEMBL15378323; CS-4615; CS 4615; CS4615. Grade: 98%. CAS No. 1391855-95-0. Molecular formula: C27H37ClN6O2. Mole weight: 513.08. | |
| CDK9-IN-7 | CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50 = 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM). CDK9-IN-7 induces NSCLC cell apoptosis, arrests the cell cycle in the G2 phase, and suppresses the stemness properties of NSCLC. Synonyms: CDK9-IN-7; 2369981-71-3; CHEMBL4548580; 7-cyclopentyl-2-[4-(8-isothiocyanatooctanoylamino)anilino]-N,N-dimethylpyrrolo[2,3-d]pyrimidine-6-carboxamideBDBM50519560. Grade: ≥99%. CAS No. 2369981-71-3. Molecular formula: C29H37N7O2S. Mole weight: 547.71. | |
| CDK9-IN-8 | CDK9-IN-8 is a highly potent and selective inhibitor of CDK9 with an IC50 of 12 nM. Synonyms: N-(4-{[7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}phenyl)-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide; 1,1-Cyclopropanedicarboxamide, N-[4-[[7-cyclopentyl-6-[(dimethylamino)carbonyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]phenyl]-N'-(4-fluorophenyl)-. Grade: ≥95%. CAS No. 2105956-51-0. Molecular formula: C31H32FN7O3. Mole weight: 569.63. | |
| CDK9-IN-9 | CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50 = 1.8 nM) with anticancer activity. It is also a CDK2 inhibitor with an IC50 of 155 nM. Synonyms: 3,20-Difluoro-10-[(S-methylsulfonimidoyl)methyl]-13-oxa-5,7,18,25-tetraazatetracyclo[17.3.1.12,6.18,12]pentacosa-1(23),2(25),3,5,8(24),9,11,19,21-nonaene; 13-Oxa-5,7,18,25-tetraazatetracyclo[17.3.1.12,6.18,12]pentacosa-1(23),2,4,6(25),8,10,12(24),19,21-nonaene, 3,20-difluoro-10-[(S-methylsulfonimidoyl)methyl]-. Grade: ≥98%. CAS No. 2246956-84-1. Molecular formula: C22H23F2N5O2S. Mole weight: 459.51. | |
| CDK9 inhibitor HH1 | CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor that inhibits the transcription of CDK and can be used in research of cancer. Synonyms: (4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone. Grade: >95.0%. CAS No. 204188-41-0. Molecular formula: C13H15N3OS. Mole weight: 261.34. | |
| CDK/CRK Inhibitor | CDK/CRK inhibitor is an inhibitor of cyclin-dependent kinases (CDK) and CDK-related kinases (CRK) with IC50 values ranging from 9-839 nM. It is also a potent, selective & ATP-competitive inhibitor of CDKs. CDK/CRK inhibitor exhibits less than 20% inhibition of 60 non-CDK/CRK kinases at 1 μM. Synonyms: Cdk7 Inhibitor IV; Cyclin-dependent kinase 7 Inhibitor IV; Cyclin-dependent kinase/CDK-related kinase Inhibitor; RGB-286147; RGB 286147. Grade: ≥98%. CAS No. 784211-09-2. Molecular formula: C23H22Cl2N4O3. Mole weight: 473.4. | |
| CDK/HDAC-IN-1 | CDK/HDAC-IN-1 has remarkable inhibitory activity against CDK2/4/6 and HDAC6 with IC50s of 60.9±2.9, 276±22.3, 27.2±4.2, and 128.6±0.4 nM, respectively. Synonyms: (E)-N-hydroxy-4-(((2'-hydroxy-1'H,3H-[2,3'-biindol]-3-ylidene)amino)oxy)butanamide. Molecular formula: C20H18N4O4. Mole weight: 378.38. | |
| CDKI-73 | CDKI-73 was cytotoxic to all of the CLL samples tested (n = 38) with a mean LD50 value of 0.08μM ± 0.10 μM following exposure to drug for 48h. In contrast, normal B-lymphocytes (n = 10) and CD34+ normal bone marrow cells (n = 5) were significantly less susceptible to the cytotoxic effects of CDKI-73. Treatment of CLL cells with 0.1 μM CDKI-73 for 4h inhibited the phosphorylation of cdk9 and ser2 of RNA polymerase II. CDKI-73 induces a rapid loss of MCL1 protein and this is mediated by significant inhibition at the level of gene transcription. However, this inhibition is not restricted to MCL1 as similar reductions in XIAP and CCND2 were also observed following exposure to CDKI-73 for 4h. CDKI-73 rapidly inhibited cellular CDK9 kinase activity and down-regulated the RNAPII phosphorylation. CDK9 shRNA was also found to down-regulate the Mnk1 expression. Both CDKI-73 and CDK9 shRNA decreased anti-apoptotic proteins Mcl-1 and Bcl-2 and induced apoptosis. CDKI-73 exhibited a favorable pharmacokinetic profile with oral bioavailability of F=56% following a single intravenous bolus dose at 2 mg/kg and an oral dose at 10 mg/kg in mice. Synonyms: CDKI-73; CDKI 73; CDKI73. Grade: >98%. CAS No. 1421693-22-2. Molecular formula: C15H15FN6O2S2. Mole weight: 394.45. | |
| CDKI-83 | CDKI-83 is a potent CDK9 inhibitor. The compound shows effective anti-proliferative activity in human tumour cell lines with GI50 <1 μM, and is capable of inducing apoptosis in A2780 human ovarian cancer cells as determined by the activated caspase-3, Annexin V/PI double staining and accumulated cells at the sub-G1 phase of cellcycle. The research results suggest that combined inhibition of CDK9 and CDK1 may result in the effective induction of apoptosis and CDKI-83 has the potential to be developed as an anti-cancer agent. Synonyms: CDKI83; CDKI 83. CAS No. 1189558-88-0. Molecular formula: C21H23N7O3S2. Mole weight: 485.58. | |
| CDK-IN-2 | CDK-IN-2 is a potent and sepecific CDK inhibitor. Synonyms: CDK inhibitor II. Grade: >98%. CAS No. 1269815-17-9. Molecular formula: C18H19ClFN3O2. Mole weight: 363.81. | |
| CDK-IN-6 | CDK-IN-6 is a CDK inhibitor with anticancer activities. Synonyms: (S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol; 2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]-, (2S)-; 2-[(2S)-1-{3-Ethyl-7-[(3-pyridinylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl}-2-piperidinyl]ethanol. Grade: ≥98%. CAS No. 779353-02-5. Molecular formula: C21H28N6O. Mole weight: 380.49. | |
| CDN 1163 | CDN 1163 is an allosteric activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2), increasing Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. It reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. CDN 1163 has the potential to treat type-2 diabetes and metabolic dysfunction. Synonyms: CDN-1163; CDN 1163; CDN1163; 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide; 4-Isopropoxy-N-(2-methylquinolin-8-yl)benzamide. Grade: ≥98% by HPLC. CAS No. 892711-75-0. Molecular formula: C20H20N2O2. Mole weight: 320.38. | |
| CDP 840 hydrochloride | CDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase 4 (PDE4) (IC50 = 12 nM). It competitively inhibits all PDE4 isoenzymes. Synonyms: CDP840; CDP-840; CDP 840; CDP840 HCl; CDP840HCl. 4-[(2R)-2-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-phenylethyl]-pyridine hydrochloride. Grade: ≥98% by HPLC. CAS No. 162542-90-7. Molecular formula: C25H27NO2.HCl. Mole weight: 409.95. | |
| CDP-β-S | CDP-β-S is a CDP binding proteins regulator with a higher stability. It is used for characterization of CDP-responsive receptors, determination of their stereospecificity and labelling with thio-reactive reporter groups. Synonyms: Cytidine- 5'- O- (2- thiodiphosphate), sodium salt. Grade: ≥ 95% by HPLC. CAS No. 497064-72-9. Molecular formula: C9H15N3O10P2S (free acid). Mole weight: 419.2 (free acid). | |
| CDP-ethanolamine | CDP-ethanolamine, a pivotal intermediary in the biosynthesis of membrane phospholipids, assumes an indispensable function in preserving cellular membrane integrity. Clinical research evince that it ameliorates cognitive development in patients diagnosed with neurodegenerative conditions, notably Alzheimer's disease. Furthermore, it potentially mitigates glaucoma symptoms by diminishing intraocular pressure while enhancing blood flow, thereby ameliorating optic nerve functionality. Synonyms: Cytidine-5'-diphosphate ethanolamine; Cytidine-5'-diphosphateethanolamine; Cytidine Diphosphate Ethanolamine. Grade: ≥ 95% by HPLC. CAS No. 3036-18-8. Molecular formula: C11H20N4O11P2. Mole weight: 446.25. | |
| CDP-Gel / CDP-Agarose | CDP-Gel is the CDP coupled to a polymeric gel by the terminal phosphate, which can be used in the affinity purification of sialyltransferases. Synonyms: Cytidine- 5'- O- diphosphate, immobilized on a polymeric matrix. | |
| CDPI3 MGB CPG | CDPI3 MGB CPG is an exquisitely tailored and purposeful compound that garners marked proficiency within the realm of biomedicine, and has demonstrated efficacy in addressing diverse manifestations of cancer. Its unique mechanism of action bespeaks its ability to regulate crucial enzymes involved in tumor expansion, exclaiming its aptitude for both solid tumors and leukemia. Moreover, corresponding research has unveiled the possibility of applying this compound as an efficacious treatment modality for autoimmune disorders. Synonyms: CDPI3 MGB CPG; CDPI3 MGB CPG 1000Å; 5-(6-(6-(6-(6-Dimethoxytrityloxyhexanoyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carboxamido)pentyl-1-O-diglycoloyl long chain alkylamino CPG. | |
| CDP - lyophilized | CDP - lyophilized is a biomedical compound used in the research of neurological disorders. Substances like Cytidine-5'-diphosphate (CDP) function as a precursor to nucleotides, contributing to RNA and DNA enhancement. This lyophilized form offering improved stability and ensures optimal compound delivery. Synonyms: Cytidine-5'-diphosphate, Sodium salt. Grade: ≥ 96% by HPLC. Molecular formula: C9H15N3O11P2 (free acid). Mole weight: 403.17 (free acid). | |
| CDPPB | CDPPB is a positive allosteric modulator of mGlu5 receptor (EC50 = 10 and 20 nM for human and rat receptors, respectively). Study shows that CDPPB has a therapeutic effect for cognitive deficits in schizophrenia and pathology in Huntington's disease. CDPPB is a potential antipsychotic and nootropic drug. Synonyms: 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide; 3-cyano-N-(2,5-diphenylpyrazol-3-yl)benzamide. Grade: ≥98% by HPLC. CAS No. 781652-57-1. Molecular formula: C23H16N4O. Mole weight: 364.4. | |
| CDy9 | CDy9, a pyrrolodiazaborinine derivative, has been found to be a fluorescent probe and could be used to detect and isolate intact stem cells. Synonyms: CDy9; CDy-9; CDy 9; (E)-2-chloro-N-(2-(5,5-difluoro-3-(2-hydroxy-5-methylstyryl)-1-methyl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)ethyl)acetamide. Grade: 98%. CAS No. 1800205-57-5. Molecular formula: C23H23BClF2N3O2. Mole weight: 457.71. | |
| CE-224535 | CE-224535 is a Purinergic receptor antagonist originated by Pfizer. Phase-II/III for Rheumatoid arthritis and Phase-II for Osteoarthritis were discontinued. Uses: Osteoarthritis; rheumatoid arthritis. Synonyms: CE-224535; CE 224535; CE224535; CE-224,535; CE 224,535; CE224,535; 2-(4-Chloro-3-(3-(1-hydroxycycloheptyl)propanoyl)phenyl)-4-((2R)-2-hydroxy-3-methoxy-propyl)-1,2,4-triazine-3,5-dione. Grade: 98%. CAS No. 724424-43-5. Molecular formula: C23H30ClN3O6. Mole weight: 480.95. | |
| CE-245677 | CE-245677 is a potent and reversible Tie2 and TrkA/B kinase inhibitor, with cellular IC50s of 4.7 and 1 nM, respectively. Synonyms: 1-(5-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carbonyl)-2-methoxyphenyl)-3-(2,4-dichlorophenyl)urea; Urea, N-[5-[[4-amino-7-(1-methylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-2-methoxyphenyl]-N'-(2,4-dichlorophenyl)-. Grade: ≥98%. CAS No. 717899-97-3. Molecular formula: C24H22Cl2N6O3. Mole weight: 513.38. | |
| CE-326597 | CE-326597 is a selective type 1 cholecystokinin receptor (CCK1R)agonist. In Mar 2009, Phase-II for Obesity in World was discontinued. Uses: Obesity. Synonyms: CE-326597; CE326597; CE 326597. (S)-2-(4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4,5-dihydro-6H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepin-6-yl)-N-benzyl-N-isopropylacetamide. Grade: 98%. CAS No. 870615-40-0. Molecular formula: C37-H34-N6-O2. Mole weight: 594.72. | |
| CE3F4 | CE3F4 is a noncompetitive Epac1 inhibitor that inhibits Epac-induced Rap activation and prevents isoprenaline-induced autophagy flux in cardiomyocytes. It has no effect on PKA activity in the presence of cAMP. Synonyms: CE3F4; CE-3-F-4; CE 3 F 4; CE-3F4; CE 3F4; 5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde. Grade: ≥98% by HPLC. CAS No. 143703-25-7. Molecular formula: C11H10Br2FNO. Mole weight: 351.01. | |
| Ceapin-A7 | Ceapin-A7 is a selective inhibitor of ATF6α with IC50 of 0.59 μM. Ceapin-A7 selectively inhibits ATF6α over ATF6β and other branches of the unfolded protein response (UPR). Synonyms: EX-A4407; BS-46571. CAS No. 2323027-38-7. Molecular formula: C20H12F6N4O3. Mole weight: 470.32. | |
| Cebranopadol | Cebranopadol is a novel first-in-class compound with potent agonist activity on opioid receptor like-1(ORL-1) and the well established mu opioid receptor. It showed antinociceptive and antihypertensive effects in a variety of different animal models of pain, suggesting its potential use for the treatment of chronic pain states. Synonyms: GRT6005; GRT 6005; GRT-6005; 6-fluoro-N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine. Grade: >98%. CAS No. 863513-91-1. Molecular formula: C24H27FN2O. Mole weight: 378.491. | |
| Cebranopadol ((1α,4α)stereoisomer) | Cebranopadol ((1,4)stereoisomer) is a stereoisomer of cebranopadol which is a potent ORL-1 agonist. Synonyms: GRT6005; GRT 6005; GRT-6005; trans-6'-Fluoro-n,N-dimethyl-4-phenyl-4',9''-dihydro-3'h-spiro(cyclohexane-1,1'-pyrano(3,4-b)indol)-4-amine. Grade: 95%. CAS No. 863513-93-3. Molecular formula: C24H27FN2O. Mole weight: 378.49. | |
| Cecropin A TFA | Cecropin A is an antibacterial peptide that exists in a variety of organisms including mammals. It has a broad-spectrum antiparasitic and antibacterial activity. Grade: 98%. Molecular formula: C184H313N53O46.xC2HF3O2. Mole weight: 4003.78 (free base). | |
| Cedinir Isoxazole Analog | Cedinir Isoxazole Analog is one of Cefdinir impurities. Cefdinir is a semi-synthetic, broad-spectrum antibiotic, used for soft tissue infections and respiratory tract infections. Molecular formula: C13H11N3O6S. Mole weight: 337.31. | |
| Cediranib dihydrochloride | Cediranib (AZD-2171; tentative trade name Recentin) is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.The drug is being developed by AstraZeneca as a possible anti-cancer chemotherapeutic agent for oral administration. Synonyms: US brand name: Recentin. Foreign brand name: Recentin. Code name: AZD2171.AZD 2171; AZD-2171. CAS No. 288383-20-0. Molecular formula: C25H27FN4O3. Mole weight: 450.5. | |
| Cediranib maleate | Cediranib maleate is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM. It also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM. It inhibits VEGF-stimulated proliferation with IC50 of 0.4 nM in vitro. It suppresses PDGF-AA with IC50 of 0.04 μM in MG63 cell lines. It even suppresses tubule sprouting at subnanomolar concentrations and inhibits VEGF-induced angiogenesis in vivo. It causes hypertrophy in bone growth plate and prevents luteal development in ovary. It shows broad spectrum activity in human tumor models at doses that are well tolerated. It causes regression of vascular tissues in human lung tumor xenografts. Synonyms: AZD 2171 maleate; Recentin; 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline maleate. Grade:>98%. CAS No. 857036-77-2. Molecular formula: C29H31FN4O7. Mole weight: 566.6. | |
| CEE321 | CEE321 is a pan JAK inhibitor. Synonyms: NVP-CEE321. Grade: 98% by HPLC. CAS No. 2098545-89-0. Molecular formula: C18H16ClN5O. Mole weight: 353.8. | |
| Ceefourin 1 | Ceefourin 1 has been found to be a selective MRP4 inhibitor (IC50 = 2.6 μM). Synonyms: Ceefourin-1; Ceefourin 1; Ceefourin1; 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione. Grade: ≥98% by HPLC. CAS No. 315702-40-0. Molecular formula: C11H10N4S3. Mole weight: 294.42. | |
| CEF6 acetate | CEF6, one of the the CEF control peptides, is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein. Synonyms: Influenza Virus NP acetate. Molecular formula: C50H82N10O16S. Mole weight: 1111.32. | |
| Cefaclor EP Impurity B | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: 7-amino-3-chloro-8-oxo-, (6R,7R)-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. CAS No. 53994-69-7. Molecular formula: C7H7ClN2O3S. Mole weight: 234.66. | |
| Cefaclor EP Impurity C | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Uses: Anti-bacterial agents. Synonyms: [6R-[6α,7β(S*)]]-7-[(Aminophenylacetyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grade: > 95%. CAS No. 143059-69-2. Molecular formula: C15H14ClN3O4S. Mole weight: 367.81. | |
| Cefaclor EP Impurity D | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: (6R,7R)-7-[[(2R)-Aminophenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid; Cefaclor Delta-3-Isomer. Grade: > 95%. CAS No. 152575-13-8. Molecular formula: C15H14ClN3O4S. Mole weight: 367.81. | |
| Cefaclor EP Impurity D (2R-Isomer) | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: (2R,6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid; Cefaclor EP Impurity D; delta-3-cefaclor. Molecular formula: C15H14ClN3O4S. Mole weight: 367.81. | |
| Cefaclor EP Impurity D (2S-Isomer) | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: (2S,6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid; Cefaclor EP Impurity D; delta-3-cefaclor. Molecular formula: C15H14ClN3O4S. Mole weight: 367.81. | |
| Cefaclor EP Impurity E | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: Cefaclor Open-Ring Impurity; 2-((R)-2-Amino-2-phenylacetamido)-2-(5-chloro-4-oxo-3,4-dihydro-2H-1,3-thiazin-2-yl)acetic Acid. Grade: 95%. CAS No. 188915-50-6. Molecular formula: C14H14ClN3O4S. Mole weight: 355.80. | |
| Cefaclor EP Impurity G | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: [6R-[6α,7β(R*)]]-7-[(Aminophenylacetyl)amino]-3-methylene-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid. Grade: > 95%. CAS No. 67308-21-8. Molecular formula: C16H17N3O4S. Mole weight: 347.39. | |
| Cefaclor EP Impurity G (2R-Isomer) | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: (2R,6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methylene-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid; Cefaclor EP Impurity G; isocefalexine. Molecular formula: C16H17ClN3O4S. Mole weight: 347.39. | |
| Cefaclor EP Impurity G (2S-Isomer) | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: (2S,6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methylene-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid; Cefaclor EP Impurity G; isocefalexine. Molecular formula: C16H17ClN3O4S. Mole weight: 347.39. | |
| Cefaclor EP Impurity H | An impurity of Cefaclor, a second-generation cephalosporin antibiotic used for the treatment of a wide variety of bacterial infections. Synonyms: (6R,7R)-7-[[(2R)-2-[[(2R)-2-amino-2-phenylacetyl]amino]-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; N-phenylglycyl cefaclor. Molecular formula: C23H21ClN4O5S. Mole weight: 500.95. | |
| Cefadroxil-d4 | Cefadroxil-d4 is a Cefadroxil. Cefadroxil is a semi-synthetic cephalosporin antibiotic used for the treatment of bacterial infections. Synonyms: (6R,7R)-7-[[(2R)-Amino-(4-hydroxyphenyl-d4)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Monohydrate; p-Hydroxycephalexine-d4 Monohydrate; BL-S578-d4; MJF-11567-3-d4; Baxan-d4. Grade: > 95%. CAS No. 1426215-61-3. Molecular formula: C16H13N3O5SD4·H2O. Mole weight: 385.44. | |
| Cefadroxil Hydrate | Cefadroxil Hydrate is an exceedingly robust antibiotic, immensely pivotal in the biomedical research. Its prime objective involves the research of diverse bacterial strains, predominantly targeting the dermal, urinary and pulmonary domains. Uses: Anti-bacterial agents. Synonyms: Cefadroxil monohydrate; 66592-87-8; Cefadroxil hydrate; Duricef; Bidocel; Cefadroxil 1-wasser; Cefadroxil (hydrate); Duracef; MJF 11567-3; BL-S578; BL-S 578; (6R,7R)-7-((R)-2-Amino-2-(p-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monohydrate; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, monohydrate, (6R,7R)-; Ultracef; Moxacef Kapseln; Baxan Kapseln; Cefos Granulat; Kefroxil Kapseln; Omnidrox Kapseln; MJF-11567-3; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,monohydrate, (6R,7R)-; 280111G160; Cefadroxil (as monohydrate). Grade: > 95%. CAS No. 66592-87-8. Molecular formula: C16H17N3O5S.H2O. Mole weight: 381.41. | |
| Cefadroxil Monohydrate EP Impurity C | an impurity of Cefadroxil. Synonyms: 2H-1,?3-Thiazine-2-acetic acid, α-[[amino(4-hydroxyphenyl)?acetyl]?amino]?-4-carboxy-5,?6-dihydro-5-methyl- (9CI). Grade: > 95%. CAS No. 147103-96-6. Molecular formula: C16H19N3O6S. Mole weight: 381.41. | |
| Cefadroxil Related Compound D | L-Cefadroxil is the stereoisomer of Cefadroxil, a smei-synthetic cephalosporin antibiotic. Antibacterial. Synonyms: [6R-[6α,7β(S*)]]-7-[[Amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R,7R)-7-[[(2S)-Amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid. Grade: > 95%. CAS No. 144790-28-3. Molecular formula: C16H17N3O5S. Mole weight: 363.39. | |
| Cefadroxil Related Compound I | Δ2-Cefadroxil is a derivative of Cefadroxil, a semi-synthetic cephalosporin antibiotic. Antibacterial. Synonyms: [6R-[6α,7β(R*)]]-7-[[Amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid; (6R,7R)-7-[[(2R)-Amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid; (6R. Grade: > 95%. CAS No. 147103-94-4. Molecular formula: C16H17N3O5S. Mole weight: 363.39. | |
| Cefadroxil Sulfoxide | Cefadroxil sulfoxide is a metabolite of cefadroxil, and is used in the synthetic preparation of oxidative cleavage of β-lactam ring of cephalosporins with chloramine T in alkaline medium. Synonyms: (6R,7R)-7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 5-oxide. Grade: > 95%. CAS No. 182290-77-3. Molecular formula: C16H17N3O6S. Mole weight: 379.39. | |
| Cefalexin Impurity (3-aminomethylene-6-phenylpiperazine-2,5-dione) | an impurity of Cefalexin. Synonyms: 2,?5-Piperazinedione, 3-(aminomethylene)?-6-phenyl-. Grade: > 95%. CAS No. 65870-51-1. Molecular formula: C11H11N3O2. Mole weight: 217.23. | |
| Cefalonium | Cefalonium is a first-generation cephalosporin antibiotic. Synonyms: Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt; 4-Carbamoyl-1-[[2-carboxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium hydroxide, inner salt; Pyridinium, 4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, (6R-trans)-; 3-(4-Carbamoylpyridylmethyl)-8-oxo-7-[α-(thien-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7-(α-Thienylacetamido)-3-(4-carbamoylpyridinomethyl)-3-cephem-4-carboxylic acid; Cepalonium; Cephalonium; Cepravin DC; Cepravin Dry Cow; Pyridinium, 4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, (6R-trans)-. Grade: ≥95%. CAS No. 5575-21-3. Molecular formula: C20H18N4O5S2. Mole weight: 458.52. | |
| Cefalonium Impurity B | Deacetylcephalothin is an impurity in the synthesis of Cefalonium and an analog of Cephalothin a first-generation cephalosporin antibiotic used as a long-acting intramammary cerate for infusion of dairy cows. Synonyms: (6R,7R)-3-(Hydroxymethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R,7R)- 3-(Hydroxymethyl)-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R-trans)-3-(Hydroxy. Grade: > 95%. CAS No. 5935-65-9. Molecular formula: C14H14N2O5S2. Mole weight: 354.41. | |
| Cefalonium Impurity C | Deacetylcephalothin Lactone is an impurity in the synthesis of Cefalonium, a first-generation cephalosporin antibiotic used as a long-acting intramammary cerate for infusion of dairy cows. Synonyms: N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-Thiopheneacetamide; (5aR-trans)-N-(1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)-2-Thiopheneacetamide; 3-(hydroxymethyl)-8-oxo-7-[2. Grade: > 95%. CAS No. 10590-10-0. Molecular formula: C14H12N2O4S2. Mole weight: 336.39. | |
| Cefamandole Impurity A | an impurity of Cefamandole. Synonyms: 5-Thia-1-azabicyclo[4.2.0]?oct-2-ene-2-carboxylic acid, 7-[[(acetyloxy)?phenylacetyl]?amino]?-3-[[(1-methyl-1H-tetrazol-5-yl)?thio]?methyl]?-8-oxo-, [6R-[6α,?7β(R*)?]?]?- (9CI). Grade: > 95%. CAS No. 36922-15-3. Molecular formula: C17H16N2O6S. Mole weight: 376.39. | |
| Cefamandole Impurity C Sodium Salt | an impurity of Cefamandole. Synonyms: 5-Thia-1-azabicyclo[4.2.0]?oct-2-ene-2-carboxylic acid, 7-[[(acetyloxy)?phenylacetyl]?amino]?-3-[[(1-methyl-1H-tetrazol-5-yl)?thio]?methyl]?-8-oxo-, monosodium salt, [6R-[6α,?7β(R*)?]?]?- (9CI). Grade: > 95%. CAS No. 36922-16-4. Molecular formula: C20H19N6O6S2. Na. Mole weight: 503.54 22.99. | |
| Cefapirin Sodium EP Impurity A | Cefapirin Sodium EP Impurity A is an impurity of cefapirin sodium which is a cephalosporin antibiotic agent. It is effective against gram-negative and gram-positive organisms. Synonyms: Cephapirin lactone; Deacetylcephapirin lactone; Acetamide, 2-(4-pyridinylthio)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-. CAS No. 60517-75-1. Molecular formula: C15H13N3O4S2. Mole weight: 363.41. | |
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