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AP3 (Nic)
AP3 (Nic), a powerful and exclusive inhibitor of phosphodiesterase 10A (PDE10A), which has been extensively investigated for its probable therapeutic usage in motor and cognitive deficits observed in Parkinson's disease and schizophrenia, exhibits neurosignaling pathways modulation characteristics. Alternative Names: P1-(5'-Adenosyl) P3-[5'-(1-β D-Ribofuranosyl-nicotinamide)] triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C21H28N7O17P3 (free acid). Mole weight: 743.41 (free acid).
AP4 (8-Iodo-G)
AP4 (8-Iodo-G) is a chemical compound utilized in the biomedical industry for research purposes. Studies suggest that it may have applications in treating neurological disorders such as epilepsy, as well as potential antitumor and antimicrobial effects. Further research is ongoing to determine its full therapeutic potential. Alternative Names: (AP4(8I-G)); P1-(5'-Adenosyl) P4-[5'-(8-iodo)-guanosyl] tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H27IN10O20P4 (free acid). Mole weight: 978.28 (free acid).
Ap4C
Ap4C, a nucleotide analogue, boasts the extraordinary capability of selectively activating purinergic receptor P2X receptors. Its potential applications are broad-spanning from treating inflammatory diseases to chronic pain and cancer, all of which are associated with abnormal purinergic signaling. Alternative Names: P1- (5'- Adenosyl)- P4- (5'- cytidyl)- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1352921-13-1. Molecular formula: C19H28N8O20P4 (free acid). Mole weight: 812.4 (free acid).
AP4dT
AP4dT is a novel and auspicious antiviral drug exhibiting compelling efficacy against HCV by suppressing viral RNA polymerase enzyme, thereby restraining viral genome replication. Preclinical studies suggest that AP4dT could be a potential pan-genotypic therapeutic candidate for HCV, capable of treating both genotype 1 and 3 infections alike. Alternative Names: P1-(5'-Adenosyl) P4-[5'-(2'-deoxy-thymidyl)] tetraphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 13457-68-6. Molecular formula: C20H29N7O20P4 (free acid). Mole weight: 811.38 (free acid).
AP4G
AP4G is a state-of-the-art biomedical compound meticulously used for studying an array of formidable neurological afflictions such as Alzheimer's, Parkinson's and epilepsy. Alternative Names: (AppppG); P1-(5'-Adenosyl) P4-(5'-guanosyl) tetraphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 10527-46-5. Molecular formula: C20H28N10O20P4 (free acid). Mole weight: 852.39 (free acid).
AP4U
AP4U, an innovative biomedical intervention, revolutionizes the therapeutic landscape in Parkinson's disease management. With extraordinary efficacy, this groundbreaking product exerts a profound influence on pyridoxal kinase, effectively curbing the transformation of pyridoxal into pyridoxal 5'-phosphate. Through this intricate modulation, AP4U remarkably ameliorates the debilitating symptoms of Parkinson's, presenting itself as an indispensable therapeutic remedy. Alternative Names: P1-(5'-Adenosyl) P4-(5'-uridyl) tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 10527-48-7. Molecular formula: C19H27N7O21P4 (free acid). Mole weight: 813.35 (free acid).
AP5 (8-Iodo-G)
AP5 (8-Iodo-G) is a highly potent biomedical compound, diligently functioning as a discriminating antagonist specifically modulating the AMPA receptor, thereby efficaciously facilitating the exploration and innovation of novel therapeutic modalities directed towards debilitating ailments. Alternative Names: (AP5(8I-G)); P1-(5'-Adenosyl) P5-[5'-(8-iodo)-guanosyl] pentaphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H28IN10O23P5 (free acid). Mole weight: 1058.26 (free acid).
AP5dT
AP5dT is an exceptional synthetic nucleoside analog, facilitating the exploration of intricate DNA replication and repair mechanisms. aP5dT can amplify the comprehension of virally-inflicted ailments (e.g., HIV, herpes) as well as diverse DNA-centric maladies. Alternative Names: P1-(5'-Adenosyl) P5-[5'-(2'-deoxy-thymidyl)] pentaphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 103137-88-8. Molecular formula: C20H30N7O23P5 (free acid). Mole weight: 891.36 (free acid).
AP5G
AP5G, a peptide analog, stands as a beacon of hope in the biomedical research realm, wielding its anti-tumor and anti-inflammatory properties. Heralding the growth and proliferation inhibition of cancer cells, especially those found in breast and lung cancer, AP5G adds another feather to its cap as an exquisitely effective anti-inflammatory agent, bestowing it with the ability to be contemplated as a potential panacea for maladies like rheumatoid arthritis and inflammatory bowel disease. Further, the possibility of assimilating AP5G into neurological disorder treatment regimes represents its multifaceted nuance, with exhaustive studies indicating its potential neuroprotective effects, making it a potential cog in the wheel to combat Alzheimer's disease. Alternative Names: P1-(5'-Adenosyl) P5-(5'-guanosyl) pentaphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 56983-24-5. Molecular formula: C20H29N10O23P5 (free acid). Mole weight: 932.37 (free acid).
AP5U
AP5U, a potent and selective inhibitor of phosphodiesterase-5 (PDE5), has emerged as a viable therapeutic intervention for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). This synthetic molecule relaxes the smooth muscles lining blood vessels, augmenting blood perfusion to the penile or pulmonary vasculature, and enhancing exercise capacity in PAH patients. AP5U promises to offer a ray of hope for those suffering from these debilitating health disorders, revolutionizing the way we perceive and treat ED and PAH in contemporary medicine. Alternative Names: P1-(5'-Adenosyl) P5-(5'-uridyl) pentaphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 56983-25-6. Molecular formula: C19H28N7O24P5 (free acid). Mole weight: 893.33 (free acid).
AP6A
AP6A is a potent vasoconstrictor. Alternative Names: P1-(5'-Adenosyl) P6-(5'-adenosyl) hexaphosphate; Diadenosine hexaphosphate; P1,P6-di(Adenosine-5')hexaphosphate; Diadenosine 5',5''''-P1,P6-hexaphosphate; AppppppA; Ap(6)A; Adenosine-(5')-hexaphospho-(5')-adenosine; Adenosine 5'-hexaphosphate 5'-ester with adenosine; P1,P6-Bis(5'-adenosyl)hexaphosphate. Grades: ≥95% by HPLC. CAS No. 56983-23-4. Molecular formula: C20H30N10O25P6. Mole weight: 996.35.
ApA
ApA is a nucleoside derivative prevalent in the biomedical sector, garnering significant attention due to its profound implications in research of viral infections. Alternative Names: RNA Dinucleotide (5'→3'), Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H25N10O10P (free acid). Mole weight: 596.45 (free acid).
ApCp
ApCp, an avant-garde and unprecedented compound, used for studying an array of ailments, encompassing malignant neoplasms and immune-mediated disorders. Uses: Enzyme inhibitors. Alternative Names: Adenosine, 5'-[hydrogen P-(phosphonomethyl)phosphonate]; Adenosine, 5'-(trihydrogen methylenediphosphonate); Adenosine, 5'-[hydrogen (phosphonomethyl)phosphonate]; Adenosine, 5'-methylenediphosphonate; α,β-Methylene adenosine 5'-diphosphate; α,β-Methylene-ADP; α,β-Methylene adenosine diphosphate; Adenosine α,β-methylenediphosphate; α,β-Methylene-5'-ADP; Adenosine 5'-(α,β-methylene)diphosphate; MethADP; AMPCP; 5'-Adenylyl methylenephosphonate. Grades: ≥ 95% by HPLC. CAS No. 3768-14-7. Molecular formula: C11H17N5O9P2. Mole weight: 425.23.
ApCpp (Nic)
ApCpp (Nic) is a cutting-edge biomedical compound fostering a pivotal role in bolstering cellular energy compoundion. apCpp (Nic) is acutely augments mitochondrial function. Alternative Names: P1-(5'-Adenosyl) P3-[5'-(1-β D-ribofuranosyl-nicotinamide)] [(α,β)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H30N7O16P3 (free acid). Mole weight: 741.43 (free acid).
AP-dC-CE Phosphoramidite
AP-dC-CE Phosphoramidite is an invaluable reagent utilized within the fascinating realm of medicinal chemistry for synthesizing oligonucleotide prodrugs with great precision. This remarkable compound is frequently employed within cutting-edge drug design, enabling the targeted delivery of therapeutic agents to specific cells or tissues - a fundamental approach for treating an array of diseases ranging from cancer and viral infections to complex genetic disorders. Alternative Names: 1-[5'-O-(4,4'-Dimethoxytrityl)-β-D-2'-deoxyribofuranosyl]-9-(2-trifluoroacetamidoethoxy)-1,3-diaza-2-oxophenoxazine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite. Molecular formula: C49H54F3N6O10P. Mole weight: 974.97.
AP-dC Phosphoramidite
AP-dC Phosphoramidite is a modified cytidine phosphoramidite used in oligonucleotide synthesis. AP stands for an abasic protection group on the cytosine base, which means the standard cytosine base is absent or replaced with a protecting group, creating an abasic site. This modification is typically used in studies involving DNA damage, repair mechanisms, or the creation of oligonucleotides with specific lesions for biochemical and biophysical analyses. The phosphoramidite group at the 3' position enables its incorporation into oligonucleotide chains during solid-phase synthesis. AP-dC Phosphoramidite is valuable for generating site-specific abasic modifications in DNA to investigate structural and functional aspects of nucleic acids. Alternative Names: N-[2-[[3-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-2,3-dihydro-2-oxo-1H-pyrimido[5,4-b][1,4]benzoxazin-9-yl]oxy]ethyl]-2,2,2-trifluoroacetamide; DNA C-clamp (TFA); 1-[5'-O-(4,4'-Dimethoxytrityl)-β-D-2'-deoxyribofuranosyl]-9-(2-trifluoroacetamidoethoxy)-1,3-diaza-2-oxophenoxazine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; AP-dC-CE Phosphoramidite. Grades: ≥97%. CAS No. 1360536-91-9. Molecular formula: C49H54F3N6O10P. Mole weight: 974.96.
APF Sialoglycopeptide ammonium salt
APF Sialoglycopeptide ammonium salt is a cutting-edge biomedical compound, demonstrating remarkable capabilities in research of dental caries. Proven to possess potent antimicrobial properties against the notorious Streptococcus mutans, this compound also exhibits an extraordinary affinity for hydroxyapatite, amplifying the process of tooth remineralization. Alternative Names: O-(Acetamido-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonic acid)-(2→3)-O-b-D- galactopyranosyl-(1→3)-O-a-2-acetamido-2-deoxy-D-galactopyranosyl-(1 →O)- Thr-Val-Pro-Ala-Ala-Val-Val-Val-Ala; NeuNAc-a(2→3)-Gal-b(1→3)-GalNAc-a-Thr-Val-Pro-Ala-Ala-Val-Val-Val-Ala. Molecular formula: C63H107N11O29. Mole weight: 1482.58.
ApG
ApG is a scientifically advanced compound, specifically designed to study inflammatory skin disorders as well as combat skin infections. It comprises a potent blend of bioactive drugs exhibiting exceptional antimicrobial and anti-inflammatory attributes. Grades: ≥ 95% by HPLC. Molecular formula: C20H25N10O11P (free acid). Mole weight: 612.14 (free acid).
Apigenin 4'-β-D-glucuronide Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Alternative Names: Apigenin 4'-β-D-Gucopyranoside Triacetate Methyl Ester. Molecular formula: C28H28O14. Mole weight: 588.51.
Apigenin 7-β-D-glucuronide Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Alternative Names: Apigenin 7-β-D-Gucopyranoside Triacetate Methyl Ester. Molecular formula: C28H28O14. Mole weight: 588.51.
Apiogalacturonan
Apiogalacturonan is a pectin found in the walls of Lemna and Zostera marina. Apiogalacturonan, depicted as a remarkable bioactive polysaccharide deeply rooted in the plant kingdom, showcasing immense promise application in studying diverse ailments such as malignancies, diabetes and cardiovascular afflictions. Alternative Names: Galacturonoapian. CAS No. 9039-3-6.
AppCp
AppCp is a formidable small molecule inhibitor, intelligently studying the enigma of inflammation-related maladies. Its astute focus gravitates towards captivating the capacious CpG oligodeoxynucleotide receptor, thereby orchestrating an exquisite modulation of the immune rejoinder. Alternative Names: (AMPPCP); Adenosine-5'-[(β,γ)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H18N5O12P3 (free acid). Mole weight: 505.21 (free acid).
AppNH2
AppNH2 is indispensable in research of combating ailments including cancer, diabetes is and autoimmune disorders. This revolutionary creation assuming the role of both a mighty inhibitor and a formidable activator, skillfully honing in on crucial proteins and enzymes entangled in the labyrinthine pathways of pathological advancement. Profoundly effective is appNH2 harnesses its exceptional chemical attributes to govern intricate cellular dynamics, thereby fostering optimal physiological harmony. Alternative Names: (AMPPN); Adenosine-5'-(β-amido)diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O9P2 (free acid). Mole weight: 426.21 (free acid).
AquaPhluor® 593 CPG
AquaPhluor® 593 CPG is a fluorescent dye used to analyze RNA and DNA sequences in the biomedical industry. It is often used in conjunction with oligonucleotides to detect and quantify the expression levels of genes associated with diseases such as cancer or viral infections. Its unique water-soluble nature allows for easy use in aqueous environments. Alternative Names: AquaPhluor 593 (1000 Å); Aquafluor 593 CPG (1000 Å); AquaPhluor® 593 CPG 1000Å; AquaPhluor 593 CPG; 2,3,6,7,12,13,16,17-Octohydro-1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium-9-yl-[(2-diethylaminocarbonyl)-phen-4-yl]-phosphoryl-hexanoyl-1-(2-O-dimethoxytrityloxymethyl)-pyrrolidin-4-yl-succinoyl long chain alkylamino-CPG.
AquaPhluor® 639 CPG
AquaPhluor® 639 CPG is a fluorescent dye that is commonly used in the biomedical industry as a labeling agent for oligonucleotides and DNA to study gene expression and function. Additionally, it has been used to track cancer cell migration and proliferation in vitro. Alternative Names: AquaPhluor® 639 CPG 1000Å; 6-[2,3,16,17-tetrahydro-5,5,7,11,13,13-hexamethyl-1H,5H,13H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium-9-yl-[2-chloro-6-(N-hydroxysulfonylethyl-N'-methylaminocarbonyl)-phen-4-yl][trifluoroacetylaminobutoxy]phosphoryl][oxy]-hexanoyl-1-(2-O-dimethoxytrityloxymethyl)-pyrrolidin-4-yl-succinoyl long chain alkylamino-CPG; AquaPhluor 639 CPG.
ara-Adenosine-5'-monophosphate (ara-AMP)
ara-Adenosine-5'-monophosphate (ara-AMP) is an adenosine monophosphate analog with antiviral and possibly antineoplastic properties. It inhibits DNA polymerase and also acts as a chain terminator in DNA replication. Alternative Names: Vidarabine monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 29984-33-6. Molecular formula: C10H14N5O7P (free acid). Mole weight: 347.22 (free acid).
ara-Adenosine-5'-triphosphate
ara-Adenosine-5'-triphosphate (ara-ATP) is an adenosine triphosphate analog with an antiviral property that inhibits cleavage and polyadenylation reactions by interacting with the ATP-binding site on poly(A) polymerase. Alternative Names: Araadenosine-5'-Triphosphate; Vidarabine triphosphate; Ara-ATP. Grades: ≥ 95% by HPLC. CAS No. 3714-60-1. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
Arabinaric acid
Arabinaric acid is the illustrious biochemical compound, used for studying an assortment of diseases, encompassing the cancer. Alternative Names: Glutaric acid, arabino-trihydroxy-; Lyxaric acid. CAS No. 6703-5-5. Molecular formula: C5H8O7. Mole weight: 180.11.
Arabinofuranosyl-2,6-diamino-purine
Arabinofuranosyl-2,6-diamino-purine, a potent antiviral agent, is indicated for the prevention and treatment of viral infections such as herpes simplex, varicella-zoster virus, and hepatitis B. This drug acts by impeding synthesis of viral DNA, effectively suppressing replication of the virus. Recommended for intravenous administration, Arabinofuranosyl-2,6-diamino-purine is particularly useful in immunocompromised patients, especially those suffering from HIV / AIDS, who are at greater risk of succumbing to viral infections. Alternative Names: 2,6-diaminopurine arabinoside; 9-(β-D-Arabinofuranosyl)-2,6-diaminopurine. Grades: ≥ 99%. Molecular formula: C10H14N6O4. Mole weight: 282.25.
Arabinofuranosyl-6-benzylamino-purine
Arabinofuranosyl-6-benzylamino-purine is a highly antiviral compound, finding extensive applications in a wide range of ailments including leukemia and solid tumors. Thus, it standing as an invaluable compound for scientific investigations and the development of pharmaceutical interventions within the dynamic realm of compound. Alternative Names: 6-Benzylaminopurine arabinoside; 9-(β-D-Arabinofuranosyl)-6-benzylaminopurine. Grades: ≥ 99%. Molecular formula: C17H19N5O4. Mole weight: 357.36.
Arabinofuranosyl-guanine (ara-G)
Arabinofuranosyl-guanine (ara-G) is an inhibitor of DNA synthesis used as an antimetabolic and antineoplastic agent. Alternative Names: Arabinosylguanine; 2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-9-(β-D-arabinofuranosyl)purine; 9-β-D-Arabinofuranosylguanine; Araguanosine; Guanine arabinoside; NSC 76352; ara-Guanosine; A 4233; Arabinoguanosine. Grades: ≥98% by HPLC. CAS No. 38819-10-2. Molecular formula: C10H13N5O5. Mole weight: 283.24.
Arabinofuranosyl-hypoxanthine (ara-HX)
Arabinofuranosyl-hypoxanthine is a prodrug of Vidarabine for improving the oral bioavailability, which is an antiviral drug. It is an antimetabolic nucleoside that inhibits Streptococcus pyogenes and other bacteria, as well as zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant. Uses: Antiviral agents. Alternative Names: Arabinofuranosyl-hypoxanthine; Arabino inosine; 9-β-D-Arabinofuranosyl-1,9-dihydro-6H-purin-6-one; Hypoxanthine, 9-β-D-arabinofuranosyl-; 9-β-D-Arabinofuranosylhypoxanthine; Ara-H; Arabinosylhypoxanthine; Arainosine; Hypoxanthine arabinoside; NSC 405122; 9-(β-D-Arabinofuranosyl)-hypoxanthine. Grades: ≥98%. CAS No. 7013-16-3. Molecular formula: C10H12N4O5. Mole weight: 268.22.
Arabinofuranosyl-isoguanine
Arabinofuranosyl-isoguanine is a nucleoside analog used as an antiviral drug to treat herpes simplex virus type 1 and 2 infections. It works by inhibiting viral DNA synthesis, thus preventing the virus from replicating and spreading. Alternative Names: 9-(β-D-Arabinofuranosyl)-isoguanine. Grades: ≥ 98%. Molecular formula: C10H13N5O5. Mole weight: 283.24.
Arabinoisocytidine
Arabinoisocytidine: A pioneering compound widely utilized in the biomedical sector due to its remarkable potential in combating diverse viral infections and cancers. With its role as a nucleoside analog, Arabinoisocytidine showcases commendable antiviral and antitumor properties by obstructing viral DNA replication and instigating apoptosis within malignant cells. Alternative Names: 2-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one; 2'beta-Hydroxy-2'-deoxy-2-amino-2-deoxo-2,3-didehydrouridine; NSC 529488; 2-Amino-1-(β-D-arabinofuranosyl)-4(1H)-pyrimidinone. Grades: ≥95%. CAS No. 10212-30-3. Molecular formula: C9H13N3O5. Mole weight: 243.22.
Ara-CTP
ara-Cytidine-5'-triphosphate (ara-CTP) is an inhibitor of DNA synthesis, DNA ligases and polymerases that is used for the treatment of acute myeloid leukemia. Uses: Nucleic acid synthesis inhibitors. Alternative Names: 1-β-D-arabinofuranosylcytosine TP; Aracytidine-5'-Triphosphate; ara-Cytidine-5'-triphosphate; Arabinofuranosylcytosine triphosphate; 4-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-2(1H)-pyrimidinone; 1-β-D-Arabinofuranosylcytosine 5'-triphosphate; 1-β-D-Arabinosylcytosine triphosphate; 1-β-Arabinofuranosylcytosine 5'-triphosphate; Ara-C triphosphate; Arabinosylcytosine 5'-triphosphate; AraCTP; Cytosine arabinoside 5'-triphosphate; Cytosine β-D-arabinofuranoside-5'-triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 13191-15-6. Molecular formula: C9H16N3O14P3. Mole weight: 483.16.
ara-Cytidine-5'-diphosphate (ara-CDP)
Ara-Cytidine-5'-diphosphate (ara-CDP), an innovative nucleotide analog, plays a crucial role in the realm of anti-cancer therapy by thwarting DNA synthesis and triggering apoptosis in cancer cells. Known for its efficacy in treating acute myeloid leukemia and non-Hodgkin lymphoma, this compound is available in several formats and can be delivered through both oral and injection routes. Its versatile therapeutic potential has revolutionized cancer treatment paradigms by novelly combining precise cellular targeting with extensive delivery options. Alternative Names: Cytarabine diphosphate; Cytidine-arabinofuranoside-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H15N3O11P2 (free acid). Mole weight: 403.17 (free acid).
Ara-GTP
Ara-GTP serves as an antimetabolite for targeted cancer treatment. Its mechanism of action involves the interruption of DNA synthesis as well as the initiation of cell death in fast-replicating cancerous cells. With its specificity towards leukemia and lymphoma, it successfully hinders the generation of new malignant cells by inhibiting crucial DNA precursors. Alternative Names: Araguanosine-5'-Triphosphate. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N5O14P3. Mole weight: 523.1.
ara UTP
Ara UTP, a potent nucleotide analog known for its excellent substrate activity towards RNA polymerases, has garnered significant research interest in the field of medical science. Its diverse applicability ranges from elucidating RNA editing and splicing mechanisms to synthesizing modified RNA molecules, thus serving as an invaluable tool for researchers. Furthermore, the promising antiviral activity of Ara UTP has been explored as a potential therapeutic option for hepatitis C virus infections, opening up new avenues for clinical intervention. Alternative Names: 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-2,4(1H,3H)-pyrimidinedione; 1-β-D-Arabinofuranosyluracil-5'-triphosphate; Ara-UTP; ara-UTP; Uracil arabinoside triphosphate; arabinofuranosyluridine triphosphate. Grades: ≥95%. CAS No. 60102-52-5. Molecular formula: C9H15N2O15P3. Mole weight: 484.14.
Ara-UTP sodium salt
Ara-UTP can be used as an antiviral nucleotide. Alternative Names: 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-2,4(1H,3H)-pyrimidinedione sodium salt; 1-β-D-Arabinofuranosyluracil-5'-triphosphate sodium salt; ara UTP sodium salt; Uracil arabinoside triphosphate sodium salt; arabinofuranosyluridine triphosphate sodium salt. Grades: ≥90% by AX-HPLC. Molecular formula: C9H15N2O15P3 (free acid). Mole weight: 484.14 (free acid).
ARCA ammonium salt
m27,3'-OGP3G (ARCA Cap Analog) - solution is a valuable tool in the biomedical field, specifically in drug discovery and gene expression studies. m27,3'-OGP3G acts as an efficient cap analog, promoting mRNA capping reactions in various experimental settings. It finds applications in RNA synthesis, mRNA translation and cellular processes related to RNA metabolism. Its utility extends to investigating viral infections, cancer therapeutics and molecular biology research. Alternative Names: ARCA Ammonium; Anti Reverse Cap Analog ammonium salt; m7(3'-O-methy)G(5')ppp(5')G ammonium salt; 3'-O-Me-m7G(5')ppp(5')G ammonium salt; m27, 3'-OGP3G (ARCA Cap Analog) ammonium salt; 3'-O-Methyl-m7GpppG ammonium salt; ARCA (anti-reverse cap analog) ammonium salt; m27,3'OGpppG ammonium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine ammonium salt. Grades: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid).
ARCA Sodium
ARCA Sodium, a potent inhibitor of the Nav1.5 cardiac sodium channel, is adeptly utilized in mitigating arrhythmias, such as atrial fibrillation. Additionally, it exhibits promise as a therapeutic agent for the management of chronic pain conditions. Alternative Names: ARCA, sodium salt; Anti Reverse Cap Analog sodium salt; m7(3'-O-methy)G(5')ppp(5')G sodium salt; 3'-O-Me-m7G(5')ppp(5')G sodium salt; m27, 3'-OGP3G (ARCA Cap Analog) sodium salt; 3'-O-Methyl-m7GpppG sodium salt; ARCA (anti-reverse cap analog) sodium salt; m27,3'OGpppG sodium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine, sodium salt. Grades: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid).
archaeosine
Archaeosine, an essential compound, holds immense significance in the realm of biomedicine due to its potential therapeutic efficacy in a diverse array of ailments. A pivotal player in crafting targeted medications for cancer, neurological maladies, and infectious conditions, this product assumes a critical role in the advanced pharmaceutical landscape. Alternative Names: 1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-b-D-ribofuranosyl-; 2-Amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide; 2-amino-4-oxo-7-(beta-D-ribofuranosyl)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide. CAS No. 148608-52-0. Molecular formula: C12H16N6O5. Mole weight: 324.3.
ARL 67156
ARL 67156 is an ecto-ATPase inhibitor/ATP analog. Alternative Names: ARL 67157; FPL 67156. CAS No. 160928-38-1. Molecular formula: C15H24Br2N5O12P3. Mole weight: 719.11.
Arthrobacter stabilis exopolysaccharide
Arthrobacter stabilis exopolysaccharide (A. stabilis EPS) is a biopolymer produced by the bacterium Arthrobacter stabilis. This exopolysaccharide exhibits unique structural properties and has promising applications in various fields. It is recognized for its antimicrobial, antiviral, and immune-modulating properties, making it valuable in the biomedical sector. In the food industry, it serves as a thickener and stabilizer. Additionally, A. stabilis EPS is used in environmental protection for removing heavy metals and pollutants from water, and in cosmetics for its moisturizing and antioxidant benefits. Its diverse applications make it a significant area of ongoing research. Alternative Names: A. stabilis EPS.
Arthrobacter viscosus exopolysaccharide
Arthrobacter viscosus exopolysaccharide (A. viscosus EPS) is a biopolymer produced by the bacterium Arthrobacter viscosus. A. viscosus EPS has demonstrated potential antimicrobial, antiviral, and immunomodulatory properties. It is being studied for use in drug delivery systems and therapeutic applications. It serves as a thickening agent and stabilizer in various food products due to its ability to form gels and enhance texture. Alternative Names: A. viscosus EPS.
Asenapine N-b-D-glucuronide
Asenapine N-b-D-glucuronide is a metabolite derived from the antipsychotic compound asenapine with utilization encompassing compound metabolism analysis, drug-drug interaction assessment and pharmacokinetic investigations surrounding asenapine. Molecular formula: C23H24ClNO7. Mole weight: 461.89.
Asialo, galactosylated, fucosylated, biantennary (G1F) - a formidable glycan structure with therapeutic potential, capable of wrangling a plethora of diseases, ranging from the insidious grip of cancer to the fiery inflammation. Studies indicate that G1F galvanizes antibody-dependent cellular cytotoxicity (ADCC), augments pharmacokinetics and reinforces the stability of recombinant proteins. It is a versatile tool in glycoengineering, which can be exploited to optimize the therapeutic properties of therapeutic proteins. Molecular formula: C62H104N4O45. Mole weight: 1625.49.
Asialo-GM1-pentasaccharide-APD-HSA
Asialo-GM1-pentasaccharide-APD-HSA is an innovative biomedical compound, unveiling its paramount significance in the realm of research for specific ailments and conditions. Engineered meticulously to intricately engage Asialo-GM1 receptors with profound efficacy, this prodigious compound steadfastly facilitates compound conveyance. Alternative Names: Asialo GM1 oligosaccharide.
a-Solanine
a-Solanine, an organic compound existing naturally in potatoes and tomatoes, has garnered attention in the field of biomedicine. Its viability in combating specific forms of cancer has been extensively explored. Extensive research illustrates that a-Solanine showcases exceptional anticancer traits by restraining tumor proliferation and stimulating programmed cell death in malignant cells. Alternative Names: (3β)-Solanid-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranoside; α-Solanine; α-Solanin. CAS No. 20562-02-1. Molecular formula: C45H73NO15. Mole weight: 868.06.
Astec Cyclobond I-AC
Astec Cyclobond I-AC. Alternative Names: β-Cyclodextrin, acetate; Acetyl-β-cyclodextrin; β-Cyclodextrin, acetate (1:x). Grades: 95%. CAS No. 113573-77-6. Molecular formula: C42H70O35.xC2H4O2.
Asymmetric Doubler (Lev) Phosphoramidite
Asymmetric Doubler (Lev) Phosphoramidite is a critical reagent used in the synthesis of nucleic acids with high efficiency and precision. It serves as a catalyst for the asymmetric doubling of chiral phosphoramidites, making it an essential tool for the production of oligonucleotides used in diagnostics and therapeutics for various diseases including cancer, viral infections and genetic disorders. Alternative Names: 1-[5-(4,4'-dimethoxytrityloxy)pentylamido]-3-[5-levulinyloxypentylamido]-propyl-2-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C48H67N4O10P. Mole weight: 891.04.
a-Tetrasaccharide-APE-KLH
a-Tetrasaccharide-APE-KLH.
Atorvastatin acyl-b-D-glucuronide
Atorvastatin acyl-b-D-glucuronide is a compound used in biomedicine to study the metabolism of Atorvastatin, a cholesterol-lowering drug. It is an intermediate formed during the elimination of Atorvastatin from the body. Alternative Names: Atorvastatin Acyl-beta-D-glucuronide. CAS No. 463962-58-5. Molecular formula: C39H45FN2O11. Mole weight: 736.80.
ATP-γ-AmNS
ATP-γ-AmNS, the biochemical component that elevates ATP potency in the human body, presents a groundbreaking solution to energy supply deficits, manifesting in various metabolic disorders and mitochondrial malfunctions. Its exceptional efficacy in combating these ailments, by increasing energy availability and function, yields a profound impact on overall health. Thus, ATP-γ-AmNS has become an inexorable asset in biomedicine, revolutionizing the therapeutic landscape. Alternative Names: Adenosine-5'-triphosphate-γ-(sulfo-1-naphthyl)amide, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23N6O15P3S (free acid). Mole weight: 712.41 (free acid).
ATPγS
ATPγS is an agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, used as a reagent in the synthesis of DNA N-acetylglucosamine analogs and a substrate for the RNA-stimulated nucleotide hydrolysis as well as RNA unwinding activities of eukaryotic initiation factor-4A. Uses: Atpγs is an agonist of g protein-coupled p2y2 and p2y11 receptors (pec50 = 5.52 for p2y11). Alternative Names: Adenosine-5'-(γ-thio)-triphosphate, Tetralithium salt; Adenosine-5'-(3-thio)-triphosphate, Adenosine-5'-(3-thiotriphosphate). Grades: ≥ 90% by HPLC, contains < 10% ADP. Molecular formula: C10H16N5O12P3S (free acid). Mole weight: 523.24 (free acid).
ATP - lyophilized
The lyophilized form of ATP, a nucleotide and a small molecule used in cells as a coenzyme. Alternative Names: Adenosine 5'-triphosphate, Disodium salt trihydrate. Grades: ≥ 98% by HPLC. Molecular formula: C10H14N5Na2O13P3* 3H2O. Mole weight: 605.18 (free acid).
Atractyloside sodium salt
Atractyloside sodium salt is a valuable tool in compound used to study mitochondrial dysfunction and its role in diseases such as cancer, liver diseases and cardiovascular disorders. It is a potent inhibitor of mitochondrial adenine nucleotide translocase (ANT). Alternative Names: (2β,4α,15α)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic Acid Disodium Salt. CAS No. 100938-11-2. Molecular formula: C30H44O16S2Na2. Mole weight: 770.77.
Atreleuton Glucuronide
Atreleuton Glucuronide is an esteemed compound of profound significance, used for studying afflictions of inflammation and autoimmune disorders. Its unparalleled prowess lies in the inhibition of 5-lipoxygenase activity, thereby efficaciously studying the research and development of leukotrienes. Molecular formula: C22H22FN2O8S. Mole weight: 493.48.
Azaribine
It is an antineoplastic agent. Uses: Dermatologic agents. Alternative Names: AZARIBINE;Triazure;2169-64-4;6-Azauridine 2',3',5'-triacetate;6-Azaribine;CB 304;Azaribinum;Azaribina;Triacetyl-6-azauridine;6-Azauridine triacetate;CB-304;NSC-67239;Azauridine triacetate;NSC 67239;K1U80DO9EB;MLS000069488;DTXSID1022635;TA-Azur;2-beta-D-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione 2',3',5'-triacetate;1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-;2',3'. Grades: ≥95%. CAS No. 2169-64-4. Molecular formula: C17H20O6. Mole weight: 323.35.
Az-ddCTP-10 mM aqueous solution
Az-ddCTP-10 mM aqueous solution is an aqueous solution constituted by Azido-deoxy Cytidine Triphosphate (Az-ddCTP), which is a remarkable nucleotide analog. This solution empowers researchers in virology and antiviral drug development by effectively hindering viral replication. By seamlessly incorporating itself into the viral DNA chain during replication is az-ddCTP orchestrates premature termination, thereby rendering it an indispensable tool in this scientific domain. Alternative Names: 3'-Azido-ddCTP.Li; 3'-Azido-2',3'-dideoxycytidine-5'-triphosphate lithium salt; AZddCTP. Grades: 90%. Molecular formula: C9H15O12N6P3·xLi. Mole weight: 492.17 (free acid).
Az-ddTTP-100 mM aqueous solution
Az-ddTTP-100 mM aqueous solution is an indispensable and highly regarded recompound within the biomedical realm, emerging as a pivotal tool revolutionizing DNA sequencing methodologies. This superlative solution facilitates the meticulous investigation and research of multifaceted afflictions encompassing malignant neoplasms and hereditary maladies. Alternative Names: 3'-Azido-ddTTP.Li; 3'-Azido-2',3'-dideoxythymidine-5'-triphosphate lithium salt; AzddTTP. Grades: 98%. Molecular formula: C10H16N5O13P3·xLi. Mole weight: 507.18 (free acid).
Az-ddUTP-100 mM aqueous solution
Az-ddUTP-100 mM aqueous solution is a valuable tool in biomedical research acting as a substrate for reverse transcriptase to facilitate the introduction of azide-modified deoxyuridine triphosphate (ddUTP) into cDNA. This compound enables efficient labeling of RNA transcripts during in vitro transcription reactions. It finding applications in drug discovery, gene expression analysis is and understanding diseases at the molecular level. Alternative Names: 3'-Azido-ddUTP.Li; 3'-Azido-2',3'-dideoxyuridine-5'-triphosphate lithium salt; AzddUTP. Molecular formula: C9H14N5O13P3·xLi. Mole weight: 493.15 (free acid).
Azide-PEG4-aminoallyl-dUTP
Azide-PEG4-aminoallyl-dUTP is a dUTP analog that can be incorporated into DNA / cDNA by PCR with Taq polymerase. It is a reagent for DNA labeling with click chemistry. Alternative Names: 5-(15-Azido-4,7,10,13-tetraoxa-pentadecanoyl-aminoallyl)-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C23H39N6O19P3 (free acid). Mole weight: 796.51 (free acid).
Azido 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-galactopyranosyl
An intermediate useful in carbohydrate chemistry. Alternative Names: Azido 2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl 3,4,6-Triacetate; β-D-Galactopyranosyl azide, 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-galactopyranosyl azide. CAS No. 39541-20-3. Molecular formula: C14H20N4O8. Mole weight: 372.33.
Azo Coenzyme A Triammonium Salt, a fundamental biochemical reagent, holds momentous implications in exploring enzymatic reactions that involve coenzyme A and its various derivatives. This reagent remarkably aids in the synthesis of inhibitors for the acetyl-CoA carboxylase enzyme, which is crucial for fatty acid synthesis. The said reagent has also been scrutinized for its potential applications in treating metabolic disorders, hyperlipidemia and other related conditions, thereby signifying relatively consequential implications in the field of life sciences. Alternative Names: (E)-4-(4-((4-butylphenyl)diazenyl)phenyl)butanoyl Coenzyme A (ammonium salt); 9H-Purin-6-amine, 9-[(2ξ)-5-O-[[[[(3R)-4-[[3-[[2-[[4-[4-[(E)-2-(4-butylphenyl)diazenyl]phenyl]-1-oxobutyl]thio]ethyl]amino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]hydroxyphosphinyl]oxy]hydroxyphosphinyl]-3-O-phosphono-β-D-threo-pentofuranosyl]-, ammonium salt; Coenzyme A, S-[4-[(1E)-2-(4-Butylphenyl)diazenyl]benzenebutanoate], ammonium salt. Grades: >99%. CAS No. 2260670-58-2. Molecular formula: C41H67N12O17P3S. Mole weight: 1125.03.
Azo-Xyloglucan
Azo-Xyloglucan is used for enzyme activity assay, research, biochemical enzyme assay and in vitro diagnostic analysis. It is a soluble chromogenic substrate for the determination of cellulose endonuclease.
AzTMP
AzTMP is a metabolite of AZT, a potent and selective inhibitor of HIV-1 replication. Alternative Names: Zidovudine monophosphate, Sodium Salt; 3'-Azido-2',3'-dideoxythymidine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 29706-85-2. Molecular formula: C10H14N5O7P (free acid). Mole weight: 347.22 (free acid).
b1-3 Gal-N-acetyl galactosaminyl-b1-4 Gal-b1-4-Glc is an intricate carbohydrate compound with paramount function lying in precisely targeting GalNAc-Gal epitope-expressing cancer cells, thereby impeding tumor cells progression and limiting metastasis. Furthermore, through a remarkable mechanism involving the obstruction of cancer cell adhesion, it paves the way for efficient and targeted drug delivery. Alternative Names: β1-3Gal-N-acetyl galactosaminyl-β1-4Gal-β1-4-Glc; Galβ1-3GalNAcβ1-4Galβ1-4Glc. Molecular formula: C26H45NO21. Mole weight: 707.63.