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| Product | Description | |
|---|---|---|
| 8-NO2-Guo | 8-NO2-Guo is used for analysis of hydrolysates of RNA stressed by nitric oxide / superoxide and peroxynitrite. Alternative Names: 8- Nitroguanosine. Grades: ≥ 98% by HPLC. CAS No. 337636-63-6. Molecular formula: C10H12N6O7. Mole weight: 328.3. |  |
| 8-OH-2'-O-Me-cAMP | 8-OH-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It can be used in patch clamp applications. Alternative Names: 8- Hydroxy- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C11H13N5O7P · Na. Mole weight: 381.2. | |
| 8-OH-Ado | 8-OH-Ado is used for analysis of oxidative / radioactive stress RNA hydrolysates. Alternative Names: 8- Hydroxyadenosine. Grades: ≥ 97% by HPLC. CAS No. 29861-67-8. Molecular formula: C10H13N6O6. Mole weight: 283.3. | |
| 8-OH-cAMP | 8-OH-cAMP is a polar analogue of cAMP used for the study of extracellular cAMP receptors. When applied by patch clamp techniques, 8-OH-cAMP remains trapped inside the cell. It exhibits a resistant effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Alternative Names: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 31356-95-3. Molecular formula: C10H11N5O7P · Na. Mole weight: 367.2. | |
| 8-OH-cGMP | 8-OH-cGMP is a cyclic guanosine monophosphate (cGMP) analog used in biomedical research. It acts as a second messenger in signal transduction pathways. 8-OH-cGMP is mainly utilized for studying the role of cGMP in various cellular processes, including smooth muscle relaxation, cell proliferation, and neurotransmission. It is also commonly used to investigate the pathophysiology and potential therapeutic targets in diseases related to altered cGMP signaling, such as hypertension, cardiovascular disorders, and neurodegenerative diseases. Alternative Names: 8- Hydroxyguanosine- 3', 5'- cyclic monophosphate. CAS No. 21082-28-0. Molecular formula: C10H11N5O8P · Na. Mole weight: 383.2. | |
| 8-Oxo-2'-deoxyadenosine | 8-Oxo-2'-deoxyadenosine is a crucial product in the biomedical industry used for studying and treating oxidative DNA damage caused by reactive oxygen species. It is a modified form of the nucleoside adenosine and serves as a biomarker for DNA damage and oxidative stress-related diseases like cancer, neurodegenerative disorders, and cardiovascular diseases. Alternative Names: 2'-Deoxy-8-oxo-adenosine;8-Oxo-dA; 6-AMINO-9-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-7H-PURIN-8-ONE; 8-Oxo-7,8-dihydro-2'-deoxyadenosine; 8-Oxo-deoxyadenosine; 8-hydroxy-2'-deoxyadenosine;6-amino-9-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7H-purin-8-one. Grades: ≥ 95%. CAS No. 62471-63-0. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| 8-Oxoadenoosine-5'-Triphosphate | 8-Oxoadenosine-5'-Triphosphate, an ATP analog crucial for cell signaling and energy transfer, is integral to studying signal transduction pathways and disease mechanisms. It also aids in the DNA sequencing and mutagenesis studies through its ability to incorporate into DNA strands. Its widespread use in research has contributed to unravelling the mysteries hidden within cancer, inflammation, and neurological disorders. Alternative Names: 8-Oxo-ATP; 8-Oxo-Adenosine-5'-Triphosphate. Grades: ≥95% by AX-HPLC. CAS No. 68745-44-8. Molecular formula: C10H16N5O14P3. Mole weight: 523.10. | |
| 8-Oxoadenosine | It is an anticancer antibiotic, oxidized nucleic acid adduct and phosmidosine precursor (P-prodrug). It can be used to treat hemochromatosis. Alternative Names: NSC 102240; NSC 90396; 7,8-Dihydro-8-oxoadenosine; 8-Hydroxyadenosine; 8-Oxo-7,8-dihydroadenosine; 6-Amino-7,9-dihydro-9-β-D-ribofuranosyl-8H-purin-8-one; 6-amino-9-(beta-D-ribofuranosyl)purin-8-(7H)-one; (2R,3R,4S,5R)-2-(6-amino-8-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Hydroxyadenosine. Grades: ≥95%. CAS No. 29851-57-8. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8-Oxo-dATP | 8-Oxo-dATP is a nucleotide analog mainly acting as a substrate for DNA polymerase during DNA enhancement and repair. 8-Oxo-dATP is involved in cellular processes related to oxidative stress and DNA damage. It can be used to study the effects of oxidative DNA damage and its association with diseases such as cancer and neurodegenerative disorders. Alternative Names: 8-Oxo-2'-deoxyadenosine-5'-Triphosphate; 8-Hydroxy-2'-deoxyadenosine 5'-triphosphoric acid. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid). | |
| 8-oxo-dG-CE Phosphoramidite | 8-oxo-dG-CE Phosphoramidite is an indispensable compound assuming a pivotal role in oligonucleotide research and development. Its contributes to the exploration of therapeutic drugs aimed at DNA repair and ailments associated with oxidative stress. Alternative Names: 5'-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-dG(ibu) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6,8-dioxo-1,6,7,8-tetrahydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DNA 8-oxo-G(iBu) amidite. Grades: 95%. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.93. | |
| 8-OXO-dG(dmf) Phosphoramidite | 8-OXO-dG(dmf) Phosphoramidite is a modified phosphoramidite in which the guanine base is oxidized at the 8-position to form 8-oxo-guanine, with the exocyclic amine at the 2-position protected by a dimethylformamidine (dmf) group. The sugar moiety is functionalized with a 3'-cyanoethyl (CE) phosphoramidite group for incorporation into oligonucleotides via automated DNA synthesis. This modification mimics oxidative DNA damage, making it a valuable tool for studying the biological effects of oxidative stress, DNA repair mechanisms, and mutagenesis. It is widely used in molecular biology and biochemistry research to investigate the role of 8-oxo-guanine in genomic stability and disease processes. Alternative Names: OXO-dG(N-dmf) Phosphoramidite; OXO-dG(N-dmf) CE Phosphoramidite; 5'-Dimethoxytrityl-N2-dimethylformamidine-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-2'-deoxy-G(DMF) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-dimethylformamidine-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 8-OXO-dG(dmf) CE Phosphoramidite; 8-OXO-dG(dmf) 3'-CE Phosphoramidite. Grades: ≥98%. CAS No. 1850359-96-4. Molecular formula: C43H53N8O8P. Mole weight: 840.92. | |
| 8-Oxo-dGDP | 8-Oxo-dGDP, a nucleotide analog, serves as a substrate for DNA polymerases and as a regulator for those enzymes associated with DNA repair in biochemical studies. Furthermore, it is employed to explore the involvement of oxidative stress in cancer and neurodegenerative diseases, such as Alzheimer's and Parkinson's. Alternative Names: 8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H15N5O11P2 (free acid). Mole weight: 443.20 (free acid). | |
| 8-Oxo-dGP4 | 8-Oxo-dGP4 is a chemical compound used in biomedical research for the study of DNA damage and repair mechanisms. It is a modified form of the nucleoside guanosine and is commonly utilized to identify and quantify oxidative damage to DNA caused by reactive oxygen species. Additionally, 8-Oxo-dGP4 has potential in the development and screening of drugs for the treatment of diseases related to DNA damage, such as cancer and neurodegenerative disorders. Alternative Names: 8-Oxo-2'-deoxyguanosine-5'-tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N5O17P4 (free acid). Mole weight: 603.16 (free acid). | |
| 8-Oxo-N2-isobutyryl-2'-deoxyguanosine | 8-Oxo-N2-isobutyryl-2'-deoxyguanosine is an exceptional biomedical compound, rendered as a discerning indicator for DNA impairment. It assumes an integral role as a substrate for DNA reparation. Its utilization propels extensive investigation into oxidative species-induced DNA lesions, thereby furnishing profound elucidation into an array of afflictions spanning cancer to neurodegenerative disorders. Alternative Names: 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE; 8-HYDROXY-N2-ISOBUTRYL-2/'-DEOXYGUANOSINE; N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,8-dioxo-1,7-dihydropurin-2-yl]-2-methylpropanamide; DTXSID40721580; MFCD22373349; N2-Isobutyryl-8-oxo-2'-deoxyguanosine; 2'-Deoxy-N-(2-methylpropanoyl)-8-oxo-7,8-dihydroguanosine; N-(8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥ 90%. CAS No. 136859-76-2. Molecular formula: C14H19N5O6. Mole weight: 353.33. | |
| 8-pCPT-2'-O-Me-5'-AMP | 8-pCPT-2'-O-Me-5'-AMP is a potential metabolite of 8-pCPT-2'-O-Me-cAMP, the specific Epac activator. Alternative Names: 8-(4-Chlorophenylthio)-2'-O-methyladenosine-5'-O-monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 1187179-94-7. Molecular formula: C17H19ClN5O7PS (free acid). Mole weight: 503.85 (free acid). | |
| 8-pCPT-2'-O-Me-Ado | 8-pCPT-2'-O-Me-Ado is the potential metabolite of 8-pCPT-2'-O-Me-cAMP, a specific Epac activator. Alternative Names: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine. Grades: ≥ 98% by HPLC. CAS No. 1187179-96-9. Molecular formula: C17H18ClN6O4S. Mole weight: 423.9. | |
| 8-pCPT-2'-O-Me-cAMP | 8-pCPT-2'-O-Me-cAMP is a PDE-stable activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has high lipophilicity and membrane permeability. Alternative Names: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥98% by HPLC. CAS No. 634207-53-7. Molecular formula: C17H16ClN5O6PS · Na. Mole weight: 507.8. | |
| 8-pCPT-2'-O-Me-cAMP-AM | 8-pCPT-2'-O-Me-cAMP-AM is a precursor of 8-pCPT-2'-O-Me-cAMP, the specific Epac agonist. 8-pCPT-2'-O-Me-cAMP is released after the metabolism of 8-pCPT-2'-O-Me-cAMP-AM by esterases. Alternative Names: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. CAS No. 1152197-23-3. Molecular formula: C20H21ClN5O8PS. Mole weight: 557.9. | |
| 8-pCPT-2'-O-Me-cGMP | 8-pCPT-2'-O-Me-cGMP is a PDE-stable, high lipophilic and membrane-permeant analogue. It can be used as a control since it has no activated effect on protein kinase G or Epac. Alternative Names: 8- (4- Chlorophenylthio)- 2'- O- methylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 625112-42-7. Molecular formula: C17H16ClN5O7PS · Na. Mole weight: 523.8. | |
| 8-pCPT-2'-O-Me-cXMP | 8-pCPT-2'-O-Me-cXMP can be used as a control since it has no activated effect on protein kinase G or Epac. Alternative Names: 8- (4- Chlorophenylthio)- 2'- O- methylxanthosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C17H15ClN4O8PS · Na. Mole weight: 524.8. | |
| 8-pCPT-2'-O-Me-Guo | 8-pCPT-2'-O-Me-Guo is the potential metabolite of the PKG- and Epac-inactive cGMP analogue8-pCPT-2'-O-Me-cGMP. Alternative Names: 8- (4- Chlorophenylthio)- 2'- O- methylguanosine. Grades: ≥ 97 % by HPLC. CAS No. 966936-60-6. Molecular formula: C17H18ClN6O6S. Mole weight: 439.9. | |
| 8-pCPT-5'-AMP | 8-pCPT-5'-AMP is a potential metabolite of 8-pCPT-cAMP that inhibits 5'-IMP dehydrogenase. Alternative Names: 8-(4-chlorophenylthio)adenosine-5'-O-monophosphate. Grades: ≥ 97 % by HPLC. CAS No. 78710-84-6. Molecular formula: C16H17ClN5O7PS. Mole weight: 489.83. | |
| 8-pCPT-Ado | 8-pCPT-Ado is the potential metabolite of 8-CPT-cAMP. Alternative Names: 8- (4- Chlorophenylthio)adenosine. Grades: ≥ 97 % by HPLC. CAS No. 86362-87-0. Molecular formula: C16H16ClN6O4S. Mole weight: 409.9. | |
| 8-pCPT-cGMP-AM | 8-pCPT-cGMP-AM is a precursor of 8-pCPT-cGMP, the PKG activator. 8-pCPT-cGMP is released after the metabolism of 8-pCPT-cGMP-AM by esterases. Alternative Names: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. CAS No. 272445-72-4. Molecular formula: C19H19ClN5O9PS. Mole weight: 559.9. | |
| 8-pCPT-Guo | 8-pCPT-Guo, a remarkable agonist with potent effects on the adenosine receptors, specifically targeting adenosine A1R and A3R. Scientific research has found it instrumental in exploring the diverse physiological mechanisms of these receptors. Furthermore, the drug holds immense potential as a treatment option for a range of debilitating conditions such as inflammation, cancer, and neurological disorders. With its multidimensional qualities, 8-pCPT-Guo stands as a compelling player in the medical research landscape. Molecular formula: C16H16ClN6O6S. Mole weight: 426.9. | |
| 8-pCPT-PET-cGMP | 8-pCPT-PET-cGMP is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to 8-Br-PET-cGMP, 8-pCPT-PET-cGMP is much more lipophilic and membrane-permeant. Alternative Names: 8- (4- Chlorophenylthio)- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C24H18ClN5O7PS · Na. Mole weight: 609.9. | |
| 8-[φ-450]-cAMP | 8-[φ-450]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright green fluorescence. Alternative Names: 8-[Pharos-450]-adenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| 8-[φ-450]-cGMP | 8-[φ-450]-cGMP can be used for studies with intact cells for its excellent lipophilicity and bright green fluorescence. Alternative Names: 8-[Pharos-450]-guanosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| 8-[φ-575]-2'-O-Me-cAMP | 8-[φ-575]-2'-O-Me-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. Alternative Names: 8-[Pharos-575]-2'-O-methyladenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. Mole weight: 731. | |
| 8-[φ-575]-cAMP | 8-[φ-575]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. A tiny hypsochromic shift would be developed while binding to PKA. Alternative Names: 8-[Pharos-575]-adenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| 8-[φ-575]-cGMP | 8-[φ-575]-cGMP is a fuorescent analogue of cGMP, which can be used for studies with intact cells on account of its high lipophilicity and bright red fluorescence. Alternative Names: 8-[Pharos-575]-guanosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. Mole weight: 500.4. | |
| 8-pHPT-2'-O-Me-cAMP | 8-pHPT-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has superior lipophilicity, membrane permeability and PDE stability. Alternative Names: 8- (4- Hydroxyphenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate , sodium salt. Grades: ≥ 98% by HPLC. CAS No. 612513-15-2. Molecular formula: C17H17N5O7PS · Na. Mole weight: 489.4. | |
| 8-PIP-cAMP | 8-PIP-cAMP is a selective cAMP analogue with a preference for site A of protein kinase A type I and for site B of type II. Compared to cAMP, it has superior stability and membrane permeability. Alternative Names: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 31357-06-9. Molecular formula: C15H20N6O6P · Na. Mole weight: 434.3. | |
| 8-pMeOPT-2'-O-Me-cAMP | 8-pMeOPT-2'-O-Me-cAMP is a specific activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It is highly lipophilic, membrane-permeant and stable for PDE. Alternative Names: 8- (4- Methoxyphenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 612513-16-3. Molecular formula: C18H19N5O7PS · Na. Mole weight: 503.4. | |
| 8-pMeOPT-Ado | 8-pMeOPT-Ado is a remarkably potent and preferential activator of adenosine receptors, has established itself as an indispensable tool within the realm of biomedical investigation. This exquisite compound serving as an unrivaled agent for deciphering the intricate involvements of adenosine receptors in multifarious pathological states, encompassing cardiac afflictions, inflammatory cascades is as well as neurodegeneration. Alternative Names: 8- (4- Methoxyphenylthio)adenosine. Grades: ≥ 97 % by HPLC. CAS No. 696674-66-8. Molecular formula: C17H19N6O6S. Mole weight: 406.4. | |
| 8-PT-Ado | 8-PT-Ado, a nucleoside analog employed for biomedical research, holds promise as an antiviral and anticancer drug. Notably, potency against leukemia and herpes simplex virus has been found. Engaging apoptosis induction, DNA synthesis inhibition, and DNA methyltransferase interference, 8-PT-Ado has also been seen to suppress the NF-κB pathway. This pathway is critical for the progression of inflammation and cancer. Alternative Names: 8- Phenylthioadenosine. Grades: ≥ 97 % by HPLC. Molecular formula: C16H17N6O4S. Mole weight: 376.4. | |
| 8-Styryl-dG CEP | 8-Styryl-dG CEP, an indispensable compound within the realm of biomedicine, assumes a pivotal role. It facilitates the creation of modified nucleosides and oligonucleotides, thus serving as a fundamental constituent. This compound's distinct structural attributes contribute significantly to drug development and therapies associated with DNA alterations, genetic manipulation, and gene suppression. CAS No. 1101864-12-3. Molecular formula: C51H59N8O7P. Mole weight: 927.04. | |
| 8-TEMPO-aminoadenosine Cyclic 3',5'-Monophosphate | 8-TEMPO-aminoadenosine Cyclic 3',5'-Monophosphate, a spin-labeled cyclic nucleotide used for the mapping of the cAMP site of protein kinase I from rabbit skeletal muscle. Alternative Names: 4-[[6-Amino-9-(3,5-O-phosphinico-β-D-ribofuranosyl)-9H-purin-8-yl]amino]-2,2,6,6-tetramethyl-1-piperidinyloxy; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, 1-Piperidinyloxy Deriv. CAS No. 54606-91-6. Molecular formula: C19H29N7O7P. Mole weight: 498.45. | |
| 8-Thioguanosine | 8-Thioguanosine is a significant compound exhibiting remarkable capabilities in studying viral infections and cancer. By proficiently curtailing viral RNA and DNA replication, it effectively subdues the menace of virulence, while concurrently impeding the enhancement of nucleic acids within cancerous cells. Uses: Adjuvants, immunologic. Alternative Names: 8-Mercaptoguanosine; 8-SH-Guo; 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-mercapto-1H-purin-6(9H)-one; 7,8-Dihydro-8-thioxoguanosine; 8-Mercapto-7,8-dihydroguanosin; 8-Tio-Guanosine; Guanosine, 8-mercapto-; NSC 79216; SQ 12760. Grades: ≥97% by HPLC. CAS No. 26001-38-7. Molecular formula: C10H13N5O5S. Mole weight: 315.31. | |
| 8-Trifluoromethyl-ADP | 8-Trifluoromethyl-ADP is a nucleoside diphosphate that plays a crucial role in energy metabolism. It serves as a substrate for enzymes involved in the synthesis of ATP, which is a key currency of cellular energy. Additionally, it is also used in research to study the regulation of various ion channels and transporters, as well as to investigate signal transduction pathways implicated in a variety of diseases such as cancer and neurological disorders. Alternative Names: 8-Trifluoromethyl-adenosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H14N5O10P2F3 (free acid). Mole weight: 495.20 (free acid). | |
| 8-(trifluoromethyl)-Guanosine | 8-(Trifluoromethyl)-Guanosine is a potent and selective antiviral compound employed in the biomedical sector, used in research of viral infections, specifically RNA viruses like hepatitis C and Zika. Alternative Names: Guanosine, 8-(trifluoromethyl)-. CAS No. 36799-14-1. Molecular formula: C11H12F3N5O5. Mole weight: 351.24. | |
| 8-Vinyl-dA CEP | 8-Vinyl-dA CEP is a cutting-edge biomedical compound, acting as a fundamental building block for custom nucleotides and oligonucleotides. CAS No. 851228-42-7. Molecular formula: C45H55N8O6P. Mole weight: 834.94. | |
| 9,10-Dimethoxy-pterocarpane-3-O-b-D-glucoside | 9,10-Dimethoxy-pterocarpane-3-O-b-D-glucoside. | |
| 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine | 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a vital compound exhibiting promising anti-viral properties and employed in the research of various viral diseases. With its unique chemical structure, It acts effectively against specific DNA and RNA viruses. Alternative Names: 2'-C-Methyl-2',3',5'-tri-O-benzoyl-beta-D-6-methylpurine riboside; 6-Methyl-9-(2-C-methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)purine. Grades: ≥95%. CAS No. 2095417-61-9. Molecular formula: C33H28N4O7. Mole weight: 592.60. | |
| 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine | 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine, an essential constituent utilized in the advancement of antiviral treatments, requires thorough investigation due to its significant implications in restraining the duplication of viral DNA. Hence, owing to its unparalleled configuration and biochemical characteristics, this compound exhibits substantial promise as a potential intervention against diverse viral infections. Moreover, its distinctive attributes may facilitate the targeting of drug-resistant variants, rendering it highly effective in combating a spectrum of viral maladies. Alternative Names: 9-(2-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine; 9-(2',3',5'-Tri-O-benzoyl-2'C-methyl-b-D-ribofuranosyl)purine. Grades: ≥95%. CAS No. 2095417-45-9. Molecular formula: C32H26N4O7. Mole weight: 578.57. | |
| 9-(2',3',5'-tri-O-benzoyl-5'-(R)-C-Methyl-b-D-ribofuranosyl)-6-chloropurine | 9-(2',3',5'-tri-O-benzoyl-5'-(R)-C-Methyl-b-D-ribofuranosyl)-6-chloropurine. | |
| 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine | 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine, commonly known as TBA, is an immensely powerful antiviral compound that displays inhibitory efficacy in research of a wide array of malignancies such as leukemia, lymphoma and solid tumors. By obstructing the propagation of viral DNA and RNA, this pharmacological compound successfully impedes the proliferation and dissemination of malignant cells. Alternative Names: 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl) adenine. CAS No. 3257-73-6. Molecular formula: C31H31N5O4. Mole weight: 537.61. | |
| 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine | 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a bioactive compound used in biomedicine to treat various diseases. It exhibits potent antiviral activity against certain types of viruses by inhibiting their replication. Additionally, it has been investigated as a potential therapeutic agent for certain cancers and autoimmune diseases due to its ability to modulate immune responses. Alternative Names: 2'-C-Methyl-beta-D-6-methylpurine riboside; 6-Methyl-9-(2-C-methyl-beta-D-ribofuranosyl)purine. Grades: ≥95%. CAS No. 2095417-06-2. Molecular formula: C12H16N4O4. Mole weight: 280.28. | |
| 9-(2-C-Methyl-b-D-ribofuranosyl)purine | 9-(2-C-Methyl-b-D-ribofuranosyl)purine is a formidable nucleoside analogrenowned for its unwavering antiviral prowess. This exceptional compound operates as a potent nucleoside reverse transcriptase inhibitor, skillfully impeding viral replication via the artful blockade of the reverse transcriptase enzyme. Alternative Names: 9-(2-C-Methyl-β-D-ribofuranosyl)purine; 9H-Purine, 9-(2-C-methyl-beta-D-ribofuranosyl)-; (2R,3R,4R,5R)-5-(Hydroxymethyl)-3-methyl-2-(9H-purin-9-yl)tetrahydrofuran-3,4-diol; 9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine. Grades: ≥95%. CAS No. 690269-86-4. Molecular formula: C11H14N4O4. Mole weight: 266.25. | |
| 9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine | 9-(2'-Deoxy-2'-fluoro-α-D-arabinofuranosyl)-9H-purin-6-amine, a remarkable compound renowned for its potent antiviral properties, is extensively utilized within the esteemed biomedical sector. This exceptional therapeutic agent plays a pivotal role in combatting a plethora of viral infections triggered by the herpes simplex, varicella-zoster, and Epstein-Barr viruses. By impeding the replication of viral DNA, it actively thwarts the proliferation and recurrence of these notorious viral maladies. Alternative Names: (2R,3R,4S,5S)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 20187-82-0. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)hypoxantine | 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)hypoxanthine, a remarkable antiviral agent and immunosuppressant, exhibits significant potential in combating viral infections such as herpes simplex virus and cytomegalovirus. A potent mechanism arises from its ability to impede viral DNA replication through chain termination, thereby obstructing viral DNA elongation. Alternative Names: 2'-FANA-I. Grades: 97%. Molecular formula: C10H11FN4O4. Mole weight: 270.22. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine | 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine, an esteemed biomedical compound, stands as a paramount weapon in combatting egregious viral entities. Harnessing its remarkable antiviral potential, this compound seamlessly infiltrates viral life cycles by selectively impeding the replication of viral enzymes. Alternative Names: 2'-Deoxy-2'-fluoroisoguanosine. Grades: 98%. Molecular formula: C10H12FN5O4. Mole weight: 285.24. | |
| 9-(2-Deoxy-2-fluoro-b-D-xylofuranosyl)-9H-purin-6-amine | 9-(2-Deoxy-2-fluoro-b-D-xylofuranosyl)-9H-purin-6-amine, commonly known as DFXY, is a remarkable antiviral agent employed for combatting specific viral infections, including hepatitis B and C. With its precise mechanism of action targeting the viral polymerase enzyme, DFXY displays remarkable effectiveness in hindering viral replication. Alternative Names: (2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-D-xylofuranosyl)-; 9-(2-Deoxy-2-fluoro-β-D-xylofuranosyl)-9H-purin-6-amine; 2'-Fluoro-2'-deoxy-β-D-xylo-adenosine. Grades: ≥97% by HPLC. CAS No. 123334-75-8. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2,6-diaminopurine (FANA-DAP) | FANA-DAP, a nucleotide analogue, exhibits the capability to target selective immune cells; cytotoxic T lymphocytes and natural killer cells, and is effective in enhancing their activity against tumor cells. This unique immunomodulatory drug shows great potential as a therapeutic agent in combating various types of cancer, including melanoma, prostate cancer, and hepatocellular carcinoma. The complex structure and mechanism of FANA-DAP make it a potential candidate for advancing cancer treatment and is a promising area of research for future studies. Grades: ≥ 97%. Molecular formula: C10H15FN6O3. Mole weight: 286.2629. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6-thioguanine (FANA-thioG) | 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6-thioguanine (FANA-thioG) is a remarkable and cutting-edge compound, exhibiting its profound impact in research of both antiviral and anticancer domains. By impeding the process of DNA enhancement, FANA-thioG effectively curbs the propagation of malignant cells and the replication of viruses. Grades: ≥ 97%. Molecular formula: C10H12FN5O3S. Mole weight: 301.2974. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)adenine (2'-FANA-A) | 2'-FANA-A, a nucleoside analog, exhibits potent antiviral and anticancer activity, rendering it an indispensable combatant against lethal pathogens such as hepatitis B and C viruses, and enervating solid tumors like lung and breast cancers. Its mechanism of action involves obstruction of viral replication and cancer cell proliferation, thereby qualifying it as a crucial weapon in the war on deadly diseases. Grades: ≥ 98%. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)guanine (2'-FANA-G) | 2'-FANA-G, a nucleotide analog, is a prime candidate for antiviral drug development. The molecule, with inherent DNA synthesis inhibition capability, demonstrates promise against viral infections such as herpes and hepatitis B, which plague millions. Clinical studies have confirmed its efficacy with potent antiviral effects and negligible toxicty. As such, it presents an exciting opportunity for further investigation into new antiviral therapy. Grades: ≥ 97%. | |
| 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)hypoxantine (2'-FANA-I) | 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)hypoxantine (2'-FANA-I), an impressive nucleoside analog, boasts effectiveness in the biomedical sector as an antiviral agent used to cure various viral infections, including HIV and hepatitis B virus. Its phenomenal capacity to impede viral replication has been substantiated by promising outcomes in clinical trials. Grades: ≥ 97%. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine | 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine is a cutting-edge biomedicine product used for the treatment of viral infections caused by Herpesviridae family, specifically herpes simplex viruses (HSV) and varicella-zoster virus (VZV). This compound exhibits potent antiviral activity by inhibiting viral DNA synthesis, thus preventing the replication of these viruses. Molecular formula: C35H36FN5O7. Mole weight: 657.69. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite | The 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-beta-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite has been proven effective against cancer. Alternative Names: 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-arabinofuranosyl-deoxyguanosine 3'-CE phosphoramidite; 2'-F-2'-ara-N2-ibu-dG phosphoramidite; Propanamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-; N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-fluoro-2'-arabinoguanosine-3'-CED-phosphoramidite; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-2-(isobutyrylamino)-1,9-dihydro-6H-purin-6-one. Grades: ≥97% by HPLC. CAS No. 1404463-20-2. Molecular formula: C44H53FN7O8P. Mole weight: 857.93. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt | 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt, an esteemed asset within the biomedical sector, stands as a pivotal driving force for combating various ailments. Notably, this heralded innovation serves as an efficacious intervention for distinct malignancies, viral affections, and autoimmunity predicaments. Imbued with an unparalleled amalgamation and intricate architecture, it inherently offers targeted remedial measures, endowing it with unsurpassed potential within the realm of precision medicine. Molecular formula: C39H39FN5O10·C6H16N. Mole weight: 858.97. | |
| 9-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl)adenine | 9-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl)adenine, a remarkably potent nucleoside analogue, finds extensive application in the realm of biomedicine. It serves as a valuable asset in crafting antiviral medications, specifically designed to combat viral DNA polymerases. Its efficacy in addressing a wide range of viral afflictions, such as HIV, herpes simplex, and hepatitis B, exhibits tremendous potential. | |
| 9-(2-Hydroxyethyl)adenine | 9-(2-Hydroxyethyl)adenine is a noteworthy bioactive nucleobase derivative extensively employed in the development of potent antiviral and antitumor therapeutics. Alternative Names: 9H-Purine-9-ethanol, 6-amino-; 6-Amino-9H-purine-9-ethanol; 2-(6-Amino-9H-purin-9-yl)ethan-1-ol; 2-(6-Amino-9H-purin-9-yl)ethanol; 9-(β-Hydroxyethyl)adenine; NSC 51467. Grades: 95%. CAS No. 707-99-3. Molecular formula: C7H9N5O. Mole weight: 179.18. | |
| 9-(2'-O-Acetyl-3',5'-di-O-benzoyl-3'-beta-C-methyl-beta-D-ribofuranosyl)-6-chloropurine | 9-(2'-O-Acetyl-3',5'-di-O-benzoyl-3'-beta-C-methyl-beta-D-ribofuranosyl)-6-chloropurine, a remarkable antiviral compound, exhibits exceptional potency against diverse viral infections. Its distinctive molecular composition facilitates precise targeting and subsequent inhibition of viral DNA or RNA replication. Consequently, vital viral replication mechanisms are impeded, resulting in the effective suppression of viral proliferation. Grades: ≥95%. Molecular formula: C27H23ClN4O7. Mole weight: 550.95. | |
| 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine | 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine, an exceptional antiviral compound, exhibits remarkable potency against diverse viral infections. Its mechanism of action involves the precise targeting of vital viral enzymes and components crucial for the life cycle of the virus. Embracing a scientific approach, this product presents a highly prospective therapeutic alternative for susceptible viral-induced diseases, exhibiting substantial efficacy validated through preclinical and clinical investigations. Alternative Names: 6-Chloro-9-[2-O-acetyl-5-O-(p-toluoyl)-3-azido-3-deoxy-beta-L-ribofuranosyl]-9H-purine. Grades: ≥95%. CAS No. 2095417-30-2. Molecular formula: C20H18ClN7O5. Mole weight: 471.85. | |
| 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine | 9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a formidable antiviral compound, exhibiting exceptional capabilities in research of various viral infections. Its mode of action involves repressing viral replication, DNA enhancement and viral nucleic acid enhancement. Alternative Names: 9-(2-O-Acetyl-5-O-benzoyl-3-deoxy-β-D-erythro-pentofuranosyl)-6-chloro-9H-purine; ((2S,4R,5R)-4-Acetoxy-5-(6-chloro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl benzoate; (5S,2R,3R)-2-(6-chloropurin-9-yl)-5-(phenylcarbonyloxymethyl)oxolan-3-yl acetate. Grades: ≥95%. CAS No. 1347118-41-5. Molecular formula: C19H17ClN4O5. Mole weight: 416.82. | |
| 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine | 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine, a remarkably powerful antiviral agent widely employed in the biomedical field, showcases its profound efficacy against a myriad of viral afflictions such as influenza, herpes, and hepatitis. Grades: ≥95%. CAS No. 2072145-40-3. Molecular formula: C20H18Cl2N4O6. Mole weight: 481.29. | |
| 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-6-chloropurine | 9-(2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-beta-D-ribofuranosyl)-6-chloropurine, a highly intricate and multifaceted compound, occupies a pivotal role in the realm of biomedical science due to its profound pharmacological implications. Esteemed for its unrivaled prowess, this compound finds immense utility in combating an array of ailments, notably a diverse range of cancers. Grades: ≥95%. CAS No. 2072145-46-9. Molecular formula: C20H19ClN4O6. Mole weight: 446.84. | |
| 9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-2-amino-6-chloro-9H-purine | 9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-2-amino-6-chloro-9H-purine is a robust antiviral compound, exhibiting inhibitory efficacy in research of a wide array of viral infections, notably hepatitis B and C. By selectively antagonizing pivotal enzymes implicated in viral nucleotide research and development, this compound powerfully inhibits viral DNA replication. Alternative Names: 9-[2-O-Acetyl-3-deoxy-3-fluoro-5-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-chloro-9H-purin-2-amine; ((2R,3R,4S,5R)-4-Acetoxy-5-(2-amino-6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate; 9-(2-O-Acetyl-5-O-toluyl-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-2-amino-6-chloro-9H-purine. Grades: ≥95%. CAS No. 1612192-25-2. Molecular formula: C20H19ClFN5O5. Mole weight: 463.85. | |
| 9-(2-O-Acetyl-5-O-(p-Toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine | 9-(2-O-Acetyl-5-O-(p-Toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine, a highly complex compound, exhibits remarkable efficacy as an antiviral agent within the biomedical sector. Alternative Names: 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluoro-6-chloroinosine; 2'-O-Acetyl-2-chloro-3'-deoxy-3'-fluoro-5'-O-toluoylinosine; ((2R,3R,4S,5R)-4-Acetoxy-5-(6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate; 9-(2-O-Acetyl-5-O-toluyl-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine; 9-[2-O-Acetyl-3-deoxy-3-fluoro-5-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-chloro-9H-purine. Grades: ≥95%. CAS No. 1612192-06-9. Molecular formula: C20H18ClN4O5. Mole weight: 448.83. | |
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