BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-[(6-Amino)hexyl]-amino-GTP - DY-776 | 8-[(6-Amino)hexyl]-amino-GTP (DY-776) is an indispensable biomolecule possessing a distinctive molecular structure, rendering it an invaluable substrate for diverse enzymatic reactions. As a result, it serving as a potent tool for investigating intricate molecular pathways linked to specific afflictions. Notably, this compound finding wide-ranging applications, encompassing the exploration of drug targets and the elucidation of cellular processes like protein research and development and signal transduction. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with DY 776, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C60H76N9O22P3S2 (free acid). Mole weight: 1432.35 (free acid). |  |
| 8-[(6-Amino)hexyl]-amino-GTP - DYQ-660 | 8-[(6-Amino)hexyl]-amino-GTP - DYQ-660 is a crucial compound acting as a potent modulator in various biological processes, primarily involved in signal transduction pathways. DYQ-660 plays a vital role in cell proliferation, differentiation and apoptosis. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H72N9O19P3S (free acid). Mole weight: 1288.20 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-GTP - DYQ-661 | DYQ-661, a potent inhibitor of small G proteins, is a biomedical industry darling, with an eye towards intracellular trafficking pathways and protein transport. Offering impressive potential for combatting various cancers and infectious diseases, it specifically targets Rab and Arf families to devastating effect. Experience the world of cutting-edge biotech with DYQ-661, the pinnacle of small G protein inhibition. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with DYQ 661, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H71N9O22P3S2 (Anion). Mole weight: 1367.25 (Anion). | |
| 8-[(6-Amino)hexyl]-amino-GTP - MANT | 8-[(6-Amino)hexyl]-amino-GTP - MANT, a chemical compound regularly employed within the biomedicine industry to track the activity of GTPases proteins that regulate crucial cellular processes, demonstrates high sensitivity and specificity. This multifunctional compound has proven incredibly useful in both clinical and basic research for studying various GTPases, notably those involved in devastating neurological disorders such as Alzheimer's and Parkinson's diseases. Its versatile applications make it a vital tool in modern biomedical research. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C24H37N8O15P3 (free acid). Mole weight: 770.52 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-GTP - OYSTER-656 | 8-[(6-Amino)hexyl]-amino-GTP is an indispensable compound extensively utilized in the research of diverse afflictions, particularly those entailing the intricate GTPase signaling pathways. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- OYSTER 656 (free acid). Mole weight: 1353.35 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-GTP - Texas Red | 8-[(6-Amino)hexyl]-amino-GTP - Texas Red, a fluorescent analog widely used in biochemical and biomedical research, possesses an incredible capacity to investigate G protein-coupled receptor signaling pathways, protein-protein interactions, and drug screening in live cells with utmost precision. What's more, it has shown promising implications for understanding cancer progression and tumor detection through its ability to monitor cell viability and proliferation. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with Texas Red, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H69N10O21P3S2 (free acid). Mole weight: 1339.22 (free acid). | |
| 8,8'-Di-Br-c-diGMP | 8,8'-Di-Br-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used for binding studies and for further modifications with spacers or labels. Alternative Names: 8-, 8'- Dibromo- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1357147-61-5. Molecular formula: C20H22Br2N10O14P2 (free acid). Mole weight: 848.2 (free acid). | |
| 8,8'-Di-Cl-c-diAMP | 8,8'-Di-Cl-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used for binding studies and for further modifications with spacers or labels. Alternative Names: 8-, 8'- Dichloro- cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H22Cl2N10O12P2. Mole weight: 727.3. | |
| 8,9-Dideoxy-28,29-dihydro-7,10-dihydroxy-35-O-(2,6-dideoxy-L-ribo-hexopyranosyl)amphotericin B | 8,9-Dideoxy-28,29-dihydro-7,10-dihydroxy-35-O-(2,6-dideoxy-L-ribo-hexopyranosyl)amphotericin B is a highly potent antifungal compound, used in research of a diverse array of fungal infections, such as aspergillosis, candidiasis and cryptococcosis. By selectively binding to ergosterol within the membranes of fungal cells, this compound disrupts their structural integrity, ultimately culminating in profound and irreversible cellular demise. Uses: Anti-bacterial agents. Alternative Names: Nystatin A3. CAS No. 62997-67-5. Molecular formula: C53H85NO20. Mole weight: 1056.24. | |
| 8,9-Di-O-acetyl-N-acetyl-2-chloro-2-deoxy-4,7-di-O-methyl-b-neuraminic acid methyl ester | 8,9-Di-O-acetyl-N-acetyl-2-chloro-2-deoxy-4,7-di-O-methyl-b-neuraminic acid methyl ester, an intriguing compound utilized in the biomedical sector, holds immense promise in combatting various ailments. Its distinctive chemical configuration presents an auspicious avenue for the creation of pharmaceuticals that target distinct cellular pathways implicated in diverse pathological scenarios. Alternative Names: β-Neuraminic acid, N-acetyl-2-chloro-2-deoxy-4,7-di-O-methyl-, methyl ester, 8,9-diacetate. CAS No. 1400692-83-2. Molecular formula: C18H28ClNO10. Mole weight: 453.87. | |
| 8-ABA-cAMP | 8-ABA-cAMP is a selective cAMP analogue oreferring site B of R I of cAMP-dependent protein kinase. It is used as a ligand in affinity chromatography and can be modified with fluorophores or other markers. Alternative Names: 8- (4- Aminobutyl)aminoadenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 82927-68-2. Molecular formula: C14H22N7O6P. Mole weight: 415.4. | |
| 8-AEA-cAMP | 8-AEA-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It can be modified with fluorophores and other markers. Alternative Names: 8- (2- Aminoethyl)aminoadenosine- 3', 5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 61363-29-9. Molecular formula: C12H18N7O6P. Mole weight: 387.3. | |
| 8-AEA-cAMP-Agarose | 8-AEA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel. | |
| 8-AET-2'-O-Me-cAMP | 8-AET-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activated by cAMP (Epac) and certain phosphodiesterases. Alternative Names: 8- (2- Aminoethylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634207-89-9. Molecular formula: C13H18N6O6PS · Na. Mole weight: 440.4. | |
| 8-AET-2'-O-Me-cAMP-Agarose | 8-AET-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxyl group immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cAMP-responsive proteins such as the exchange protein activated by cAMP (Epac) and certain phosphodiesterases. Alternative Names: 8- (2- Aminoethylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel. | |
| 8-AET-cAMP | 8-AET-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores or other markers. Alternative Names: 8- (2- Aminoethylthio)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 53546-96-6. Molecular formula: C12H17N6O6PS. Mole weight: 404.3. | |
| 8-AET-cAMP-Agarose | 8-AET-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 8- (2- Aminoethylthio)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel. | |
| 8-AET-c-diAMP | 8-AET-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Alternative Names: 8- (2- Aminoethylthio)- cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H29N11O12P2S (free acid). Mole weight: 733.6 (free acid). | |
| 8-AET-c-diAMP-Agarose | 8-AET-c-diAMP-Agarose is the bacterial second messenger c-diAMP immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity chromatography of c-diAMP-responsive proteins. Alternative Names: 8- (2- Aminoethylthio)- cyclic diadenosine monophosphate, immobilized on agarose gel. | |
| 8-AET-c-diGMP | 8-AET-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Alternative Names: 8- (2- Aminoethylthio)- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H29N11O14P2S (free acid). Mole weight: 765.6 (free acid). | |
| 8-AET-c-diGMP-Agarose | 8-AET-c-diGMP-Agarose is the bacterial second messenger c-diGMP immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity chromatography of c-diGMP-responsive proteins. Alternative Names: 8- (2- Aminoethylthio)- cyclic diguanosine monophosphate, immobilized on agarose gel. | |
| 8-AET-cGMP | 8-AET-cGMP is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Alternative Names: 8- (2- Aminoethylthio)guanosine- 3', 5'- monophosphate. Grades: ≥ 98% by HPLC. CAS No. 115974-70-4. Molecular formula: C12H17N6O7PS. Mole weight: 420.4. | |
| 8-AET-cGMP-Agarose | 8-AET-cGMP-Agarose is the second messenger cGMP immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 8-AET-GTP | 8-AET-GTP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Alternative Names: 8-(2-Aminoethylthio)guanosine-5'-O-triphosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H21N6O14P3S (free acid). Mole weight: 598.3 (free acid). | |
| 8-AHA-2-Cl-cAMP | 8-AHA-2-Cl-cAMP is a selective cAMP analogue that has a preference for side B I of PKA. Alternative Names: 8- (6- Aminohexylamino)- 2- chloroadenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C16H25ClN7O6P. Mole weight: 477.8. | |
| 8-AHA-2'-O-Me-cAMP | 8-AHA-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activated by cAMP (Epac) and certain phosphodiesterases. Alternative Names: 8- (6- Aminohexyl)amino- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C17H28N7O6P. Mole weight: 457.4. | |
| 8-AHA-2'-O-Me-cAMP-Agarose | 8-AHA-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cAMP-responsive proteins such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Alternative Names: 8- (6- Aminohexylamino)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 8-AHA-cAMP | 8-AHA-cAMP is a selective cAMP analogue preferring site B of R I of cAMP-dependent protein kinase. It can be active to site A of R I and site B of R II combining with 8-PIP-cAMP. Alternative Names: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 39824-30-1. Molecular formula: C16H26N7O6P. Mole weight: 443.4. | |
| 8-AHT-cGMP | 8-AHT-cGMP is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Alternative Names: 8- (6- Aminohexylthio)guanosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 144510-13-4. Molecular formula: C16H25N6O7PS. Mole weight: 476.5. | |
| 8-AHT-GTP | 8-AHT-GTP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Alternative Names: 8-(6-Aminohexylthio)guanosine-5'-O-triphosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H29N6O14P3S (free acid). Mole weight: 654.4 (free acid). | |
| 8-Allyloxy-2'-deoxyguanosine | 8-Allyloxy-2'-deoxyguanosine, a remarkable biomedicine, exhibits immense potential for therapeutic applications in diverse medical conditions. Meticulous investigations have shed light on its profound impact in combatting cancer, viral infections, and genetic disorders, rendering it a focal point of research. By delicately manipulating intricate cellular pathways and precisely targeting molecular processes, this compound showcases its capabilities as a formidable treatment strategy. Grades: ≥ 90%. CAS No. 869354-71-2. Molecular formula: C13H17N5O5. Mole weight: 323.20. | |
| 8-Allyloxyadenosine | 8-Allyloxyadenosine, a biomedical marvel, boasts an expanse of therapeutic benefits, unyielding in its conquest against diverse maladies. Manifesting potent pharmacological prowess, it harnesses unrivaled potential in curbing viral onslaughts and quelling tumorous aberrations. Pioneering the realm of targeted therapies, it galvanizes hopes for assailing viral infections and unraveling the mystifying realms of cancer. Grades: ≥95%. CAS No. 2095417-69-7. Molecular formula: C13H17N5O5. Mole weight: 323.30. | |
| 8-(Allyloxy)guanosine | A guanosine derivative as an immunostimulant. Alternative Names: 8-Allyloxyguanosine; 8-(2-Propenyloxy)guanosine; Guanosine, 8-(2-propen-1-yloxy)-; 8-(Allyloxy)-2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 126138-81-6. Molecular formula: C13H17N5O6. Mole weight: 339.30. | |
| 8-Allyloxy-N2-(dimethylaminomethylidene)-2'-deoxyguanosine | With its intricate chemical structure, the 8-Allyloxy-N2-(dimethylaminomethylidene)-2'-deoxyguanosine emerges as a noteworthy bioactive compound in the realm of biomedicine. Garnering attention for its potential as an antiviral agent, this compound exhibits remarkable efficacy against a wide array of viral infections, specifically targeting those caused by DNA viruses. Functionally, it efficiently hones in on specific viral strains, impeding their replication through the disruption of viral DNA synthesis. In the context of antiviral therapeutic development, this compound emerges as a specialized tool of immense value. Alternative Names: N'-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-prop-2-enoxy-1H-purin-2-yl]-N,N-dimethylmethanimidamide. Grades: ≥ 90%. CAS No. 869354-73-4. Molecular formula: C16H22N6O5. Mole weight: 378.35. | |
| 8-Allyloxy-N2-isobutyryl-2'-deoxyguanosine | 8-Allyloxy-N2-isobutyryl-2'-deoxyguanosine is a novel compound with potential biomedical applications. It exhibiting antiviral properties and may be used in the development of drugs to research viral infections, such as herpes simplex virus. Alternative Names: N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-prop-2-enoxy-1H-purin-2-yl]-2-methylpropanamide. Grades: ≥ 90%. CAS No. 869354-75-6. Molecular formula: C17H23N5O6. Mole weight: 393.40. | |
| 8-Allylthioguanosine | 8-Allylthioguanosine is an exceptional compound, showcasing its remarkable efficacy in research of a wide array of viral infections. It exerts its inhibitory prowess by perturbing the intricate process of viral nucleic acid enhancement, thereby impeding the replication and dissemination of notorious viruses such as herpes simplex virus and human immunodeficiency virus (HIV). Alternative Names: 8-(2-propenylthio)guanosine; 8-(2-propenylmercapto)guanosine; 8-Allylsulfanyl-2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-prop-2-enylsulfanyl-1H-purin-6-one; 8-(Allylsulfanyl)guanosine; Guanosine, 8-(2-propen-1-ylthio)-. Grades: ≥95%. CAS No. 126092-30-6. Molecular formula: C13H17N5O5S. Mole weight: 355.37. | |
| 8-Amino[1''-(N''-dansyl)-4''-aminobutyl]-5'-(1-aziridinyl)-5'-deoxy Adenosine | A fluorescent cofactor reagent for the sequence-specific labeling of DNA methyltransferase from Thermus aquaticus (M*Taql). It binds about 4-fold better than the natural cofactor AdoMet to M*Taql. In addition, the reagent can be used to sequence-specifically label plasmid DNA in a M*Taql-catalyzed reaction. Alternative Names: 9-[(2xi)-5-(Aziridin-1-yl)-5-deoxy-beta-D-threo-pentofuranosyl]-N~8~-(4-{[5-(dimethylamino)naphthalene-1-sulfonyl]amino}butyl)-9H-purine-6,8-diamine; N-[4-[[6-amino-9-[(2R,4R,5R)-5-(aziridin-1-ylmethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]amino]butyl]-5-(dimethylamino)naphthalene-1-sulfonamide; 8-Amino[1"-(N"-dansyl)-4"-aminobutyl]-5'-(1-aziridinyl)-5'-deoxy Adenosine; DTXSID90675569; 8-Amino[1 inverted exclamation mark+/--(N inverted exclamation mark+/--dansyl)-4 inverted exclamation mark+/--aminobutyl]-5 inverted exclamation mark -(1-aziridinyl)-5 inverted exclamation mark -deoxy Adenosine. Grades: > 95%. CAS No. 256953-68-1. Molecular formula: C28H37N9O5S. Mole weight: 611.72. | |
| 8-Amino-2'-deoxyadenosine | 8-Amino-2'-deoxyadenine is an antineoplastic compound manifesting proficiency in hampering the enhancement of DNA and RNA. Alternative Names: 6,8-Diamino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine; NSC 101167; (2R,3S,5R)-5-(6,8-diamino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Grades: ≥95%. CAS No. 13389-09-8. Molecular formula: C10H14N6O3. Mole weight: 266.26. | |
| 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a vital component used in the research and development of oligonucleotides for drug discovery. It offers efficient coupling to ensure accurate incorporation of adenosine nucleotides during the solid-phase research and development process. Alternative Names: 5'-Dimethoxytrityl-N6,N8-bis(dimethylaminomethylidine)-8-amino-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-Amino-dA-CE Phosphoramidite; 8-Amino-2'-deoxy-D-adenosine 3'-CE phosphoramidite. CAS No. 211676-21-0. Molecular formula: C46H59N10O6P. Mole weight: 879.01. | |
| 8-Amino Adenosine | The purine nucleoside analog; has role in induction of apoptosis in multiple myeloma. Uses: The purine nucleoside analog. Alternative Names: 8-Aminoadenosine; 6,8-Diamino-9-β-D-ribofuranosyl-9H-purine; NSC 90394; (2R,3R,4S,5R)-2-(6,8-diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Amino-D-adenosine. Grades: ≥95%. CAS No. 3868-33-5. Molecular formula: C10H14N6O4. Mole weight: 282.26. | |
| 8-Aminoadenosine-5'-triphosphate lithium salt | 8-Aminoadenosine-5'-triphosphate lithium salt is a pivotal biochemical compound characteristically employed in cellular research to investigate the mechanisms elucidating the varied roles of ATP, encompassing signal transduction and energy transfer. Its diverse derivatives, owing to their ability to modulate the activity of an array of ion channels and transporters, display a promising potential in battling afflictions like hypertension, arrhythmia, as well as cancer. Alternative Names: 8-Amino-ATP. Molecular formula: C10H17N6O13P3·xLi. Mole weight: 522.20 (free acid). | |
| 8-Amino-Inosine | 8-Amino-Inosine is a derivative of Inosine, a nucleoside that is found in tRNAs and is essential for the proper translation of genetic code in a wobble base pair. Inosine is also known to exert neuroprotective properties and has been used to treat stroke patients to restore neural function. 8-Amino-Inosine have been studied as a potential chemotherapeutic agent for the treatment of leukemia function by the cytodestruction of the neoplastic cells. Alternative Names: NSC 109320. Grades: 96%. CAS No. 13389-16-7. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8-APT-cGMP | 8-APT-cGMP is an isozyme-selective stimulator of cGMP-dependent protein kinase I a with a prenference for type I a over I by a factor of 200. Alternative Names: 8- (2- Aminophenylthio)guanosine- 3', 5'- monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 144509-87-5. Molecular formula: C16H16N6O7PS · Na. Mole weight: 490.4. | |
| 8-Aza-2'-beta-C-methylguanosine | 8-Aza-2'-beta-C-methylguanosine: One compound, with a rather intricate name - 8-Aza-2'-beta-C-methylguanosine, finds significant application in the biomedical sector for research and development. In fact, scientists readily exploit its synthetic forerunner role while manufacturing a range of antiviral medications targeting RNA viruses, an area of paramount importance. Its unmatched constitution and characteristics render it an indispensable asset in the realm of drug exploration and medicinal chemistry, fostering the battle against debilitating viral afflictions. Grades: ≥95%. Molecular formula: C10H14N6O5. Mole weight: 298.26. | |
| 8-Aza-2'-deoxyadenosine | 8-Aza-2'-deoxyadenosine, a potent compound widely employed in the biomedical sector, exhibits immense potential for the treatment of diverse malignancies, notably leukemia and lymphoma. Its efficacy lies in its ability to impede DNA and RNA synthesis, culminating in the robust suppression of tumor proliferation. As a pivotal research asset, this nucleoside analog enables in-depth elucidation of oncogenic mechanisms and facilitates the innovative formulation of therapeutic interventions. Molecular formula: C9H12N6O3. Mole weight: 252.23. | |
| 8-Aza-5'-AMP | 8-Aza-5'-AMP, a nucleoside analog, has been widely employed in exploring the activity of purine nucleoside phosphorylase (PNP) and its role in immune system functionality. Moreover, it maintains immense potential for conducting experiments on T-cell depletion and treating severe ailments like autoimmune diseases and cancer. Alternative Names: 8- Azaadenosine- 5'- O- monophosphate. Molecular formula: C9H13N6O7P (free acid). Mole weight: 348.2 (free acid). | |
| 8-Aza-7-deaza-2'-deoxyadenosine (4-Amino-1-(2-deoxyribofuranosyl)pyrazolo[3,4-d]-pyrimidine) | 8-Aza-7-deaza-2'-deoxyadenosine (4-Amino-1-(2-deoxyribofuranosyl)pyrazolo[3,4-d]-pyrimidine), an extensively researched and scientifically proven potent anticancer drug, demonstrates exceptional efficacy in impeding DNA synthesis and growth of cancer cells. This remarkable compound exhibits impressive results in precisely targeting and inhibiting cancer progression, positioning itself as an invaluable asset within the realm of biomedicine. Grades: ≥ 95%. CAS No. 17318-21-7. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| 8-Aza-7-deaza-2'-deoxyguanosine | 8-Aza-7-deaza-2'-deoxyguanosine, an indispensable component, significantly contributes to the advancement of antiviral pharmaceuticals aimed at countering ailments engendered by DNA viruses, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its paramount function lies in impeding viral duplication through the disruption of viral DNA synthesis. Grades: ≥ 95%. CAS No. 100644-70-0. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| 8-Aza-7-deaza-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite | 8-Aza-7-deaza-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a remarkably efficient phosphoramidite building block employed in solid-phase research and development, facilitating the generation of modified RNA or DNA oligonucleotides. Through its incorporation, 8-aza-7-deaza modifications are introduced. Alternative Names: 5'-Dimethoxytrityl-N-dimethylformamidine-8-aza-7-deaza-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG). Grades: 95%. CAS No. 500891-26-9. Molecular formula: C43H53N8O7P. Mole weight: 824.91. | |
| 8-Aza-7-deaza-A CEP | 8-Aza-7-deaza-A CEP is a vital compound used in the biomedical industry. With its unique chemical properties, it plays a crucial role in the synthesis of drugs targeting various diseases. This product is extensively utilized in the research and development of pharmaceuticals aimed at treating cancer, viral infections, and neurological disorders. Molecular formula: C53H66N7O8PSi. Mole weight: 988.19. | |
| 8-Aza-7-deaza-A-CE Phosphoramidite | 8-Aza-7-deaza-A-CE Phosphoramidite, a chemical compound utilized for oligonucleotide synthesis, is a powerful tool for modifying nucleic acid structures in pharmaceutical applications and gene regulation studies. Its exceptional utility extends to therapeutic strategies in genetic disorders and cancer treatment development. Alternative Names: 5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-aza-7-deaza-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C49H67N8O7PSi. Mole weight: 939.16. | |
| 8-Aza-ATP | 8-Aza-ATP, a powerful and discriminating activator of the P2Y1 receptor, plays a critical role in an array of physiological processes, including platelet aggregation and neuroprotection. Its therapeutic uses have been explored in a litany of conditions, ranging from stroke and traumatic brain injury to glaucoma, and even hold promise for treating cancer via its potent antiproliferative and antitumor qualities. Alternative Names: 8-Azaadenosine-5'-Triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C9H15N6O13P3. Mole weight: 508.1. | |
| 8-Aza-cAMP | 8-Aza-cAMP is a paramount compound manifesting as a chemical mimic of cyclic adenosine monophosphate (cAMP). This compound exerts preferential impediment upon the aberrant proliferation of neoplastic cells. Alternative Names: 8- Azaadenosine- 3', 5'- cyclic monophosphate. CAS No. 67190-31-2. Molecular formula: C9H10N6O6P · Na. Mole weight: 352.2. | |
| 8-Azaguanosine | 8-Azaguanosine is a modified nucleoside where a nitrogen atom replaces the carbon at the eighth position of the guanine base. This alteration can impact base pairing and hydrogen bonding properties. It is used in biochemical and molecular biology research to study nucleic acid interactions, enzyme activity, and the structural effects of nucleobase modifications. Additionally, 8-azaguanosine is investigated for its potential antiviral and anticancer properties due to its ability to interfere with nucleic acid metabolism. Alternative Names: Azaguanosine; NSC 46788; NSC 130283; 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 3H-v-Triazolo[4,5-d]pyrimidin-7(6H)-one, 5-amino-3-β-D-ribofuranosyl-; 3H-v-Triazolo[4,5-d]pyrimidin-7-ol, 5-amino-3-β-D-ribofuranosyl-; 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,4-dihydro-3-β-D-ribofuranosyl-; 7H-v-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-3-β-D-ribofuranosyl-. Grades: ≥95%. CAS No. 2133-80-4. Molecular formula: C9H12N6O5. Mole weight: 284.23. | |
| 8-Azahypoxanthine | 8-Azahypoxanthine is an antimalarial agent that inhibits hypoxanthine-guanine-xanthine phosphoribosyl transferase. Alternative Names: 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 3,6-dihydro-; 3,6-Dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 1,4-dihydro-; 7H-v-Triazolo[4,5-d]pyrimidin-7-one, 1,6-dihydro-; 1H,4H,7H-[1,2,3]Triazolo[4,5-d]pyrimidin-7-one; 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-ol; 1H-v-Triazolo[4,5-d]pyrimidin-7-ol; 2,3-Dihydrotriazolo[4,5-d]pyrimidin-7-one; 7-Hydroxy-1,2,3,4,6-pentaazaindene; 7-Hydroxy-v-triazolo[d]pyrimidine; NSC 22709. Grades: ≥95%. CAS No. 2683-90-1. Molecular formula: C4H3N5O. Mole weight: 137.10. | |
| 8-Azido-2'-deoxyadenosine | 8-Azido-2'-deoxyadenosine is a potent nucleoside analogue extensively for its ability to selectively inhibit DNA enhancement. This versatile compound finding application in the research of various diseases, including cancers and viral infections. Alternative Names: (2R,3S,5R)-5-(6-amino-8-azido-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; Adenosine, 8-azido-2'-deoxy-. Grades: ≥95%. CAS No. 131265-35-5. Molecular formula: C10H12N8O3. Mole weight: 292.17. | |
| 8-Azidoadenosine 5'-monophosphate sodium salt | 8-Azidoadenosine 5'-monophosphate sodium salt is a biomedical compound commonly used in drug discovery and development. This product plays a vital role in studying the detailed mechanisms of various diseases, including cancer, viral infections, and neurological disorders. By acting as a precursor to adenosine triphosphate (ATP), it aids in investigating and evaluating potential therapeutic targets and drug candidates for these conditions. CAS No. 60731-47-7. Molecular formula: C10H13N8O7P. Mole weight: 388.23. | |
| 8-Azidoadenosine 5'-triphosphate tetralithium salt | 8-Azidoadenosine 5'-triphosphate tetralithium salt, a pivotal agent in the field of biomedicine, serves as an indispensable resource for the investigation of kinase activity and phosphorylation occurrences. Through its utilization as a photoaffinity probe, this compound facilitates the identification and characterization of proteins that bind to adenosine triphosphate (ATP). Its remarkably potent nature renders it a valuable asset in the realm of drug discovery and development. Grades: 85%. Molecular formula: C10H15N8O13P3. Mole weight: 548.19. | |
| 8-Azido-ATP-gamma-biotin sodium salt | 8-Azido-ATP-gamma-biotin sodium salt is a paramount recompound employed in cutting-edge biomedical investigations, exhibiting extraordinary versatility in probing protein-nucleotide interactions. Its unique azide moiety facilitates the covalent conjugation of biotin, thereby facilitating the monitoring of biotin-labeled proteins within intricate biological frameworks. Grades: 95%. Molecular formula: C25H41N12O14P3S. Mole weight: 858.65 (free acid). | |
| 8-Benzyloxy-2'-deoxyadenosine | 8-Benzyloxy-2'-deoxyadenosine, an exceptionally powerful antiviral agent, finds its application in combating formidable viral adversaries like HIV and hepatitis B. Remarkably, its inhibitory effect on viral replication and consequential hinderance of viral dissemination unveil its therapeutic prowess. This extraordinary compound, when integrated into nucleic acids, induces a perturbation in viral RNA synthesis, culminating in the abatement of viral replication. Alternative Names: (2R,3S,5R)-5-(6-Amino-8-(benzyloxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 8-BENZYLOXY-2/'-DEOXYADENOSINE; (2R,3S,5R)-5-(6-amino-8-phenylmethoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;(2R,3S,5R)-5-[6-amino-8-(benzyloxy)-9H-purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol. Grades: ≥ 97%. CAS No. 142948-07-0. Molecular formula: C17H19N5O4. Mole weight: 357.37. | |
| 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine | 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine, a highly significant compound utilized in the field of biomedicine, assumes a pivotal function in combating diverse viral infections and cancers. Its unique mechanism involves the inhibition of specific viruses, thereby showcasing potent antiviral characteristics. Moreover, its exceptional potential as an agent against cancer lies in its capacity to impede the growth and proliferation of malignant cells. Alternative Names: 2-amino-9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grades: ≥95%. CAS No. 2389988-61-6. Molecular formula: C17H18FN5O5. Mole weight: 391.35. | |
| 8-Benzyloxy-3'-deoxyguanosine | 8-Benzyloxy-3'-deoxyguanosine, an extensively studied biomedicine, stands as a beacon of hope in combating viral infections, especially within the realm of antiviral therapeutics. Notably, this remarkable compound unveils an impressive repertoire, showcasing its potent antiviral prowess against an array of DNA and RNA viruses. Lending credence to its potential for drug development, it boasts a mechanism of action centered around inhibiting viral replication. Alternative Names: Guanosine, 3'-deoxy-8-(phenylmethoxy)-; 2-amino-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grades: ≥95%. CAS No. 2389988-57-0. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-Benzyloxy-9-(b-D-xylofuranosyl)guanine | 8-Benzyloxy-9-(b-D-xylofuranosyl)guanine, a formidable antiviral compound widely utilized in the biomedical sector, boasts a remarkable repertoire of vital functions. Its exceptional potency enables the efficacious extermination of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections, cementing its significance in combating viral afflictions. Unraveling its dynamic mechanism of action reveals an intricate disruption of viral DNA replication, debilitating the pernicious proliferation of these malevolent entities. Alternative Names: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grades: ≥95%. Molecular formula: C17H19N5O6. Mole weight: 389.36. | |
| 8-Benzyloxyadenosine | 8-Benzyloxyadenosine is a key compound in biomedicine used for its potential therapeutic benefits in treating various diseases. It acts as an adenosine receptor agonist, primarily targeting A1 and A3 receptors. This unique property makes it an essential tool in studying the role of adenosine receptors in conditions such as cardiovascular diseases, cancer, and neurodegenerative disorders. Alternative Names: Adenosine, 8-(phenylmethoxy)-; (2R,3R,4S,5R)-2-(6-Amino-8-(benzyloxy)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 131265-29-7. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-(Benzyloxy)guanosine | 8-(Benzyloxy)guanosine is a vital bioactive compound exhibiting potential in studying various diseases, such as cancer. With its inhibition abilities, it targets specific cellular pathways. Alternative Names: 8-Benzyloxy-Guanosine; 8-(Phenylmethoxy)guanosine; NSC 90391; 8-Benzyloxyguanosine; 2-Amino-8-(benzyloxy)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 8-(phenylmethoxy)-; Guanosine, 8-(benzyloxy)-. Grades: ≥95%. CAS No. 3868-36-8. Molecular formula: C17H19N5O6. Mole weight: 389.36. | |
| 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine | 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine is an antiviral compound, holding immense potential in the development of antiviral therapeutics. Alternative Names: N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-phenylmethoxy-1H-purin-2-yl]-2-methylpropanamide; 8-BENZYLOXY-N2-ISOBUTYRYL-2/'-DEOXYGUANOSINE;8-(Benzyloxy)-2'-deoxy-N-(2-methylpropanoyl)guanosine; N-(8-(benzyloxy)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥ 90%. CAS No. 136859-75-1. Molecular formula: C21H25N5O6. Mole weight: 443.46. | |
| 8-Biotin-11-cAMP | 8-Biotin-11-cAMP is a biochemical compound used in biomedicine research to investigate cAMP-mediated cellular signaling pathways. It is commonly used in molecular pharmacology and drug discovery to characterize the effects and pharmacokinetics of various drugs related to cAMP. Additionally, 8-Biotin-11-cAMP is used as a tool to study and target certain diseases, such as cancer and metabolic disorders, where cAMP signaling plays a role in their pathophysiology. Grades: ≥ 98% by HPLC. Molecular formula: C28H41N9O9PS2 · Na. Mole weight: 765.8. | |
| 8-Biotin-11-c-diAMP | 8-Biotin-11-c-diAMP is an analogue of c-diAMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Grades: ≥ 95% by HPLC. Molecular formula: C38H54N14O15P2S2 (free acid). Mole weight: 1073 (free acid). | |
| 8-Biotin-11-c-diGMP | 8-Biotin-11-c-diGMP is an analogue of c-diGMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Grades: ≥ 95% by HPLC. Molecular formula: C38H54N14O17P2S2 (free acid). Mole weight: 1105 (free acid). | |
| 8-Biotin-11-cGMP | 8-Biotin-11-cGMP, a cyclic guanosine monophosphate (cGMP) analog, boasts extensive use within scientific research wherein protein kinases and physiological processes, including smooth muscle relaxation and platelet activation, are studied. Studies have also hinted at the prospect of employing 8-Biotin-11-cGMP in combating diseases characterized by hypertension and erectile dysfunction. Grades: ≥ 98% by HPLC. Molecular formula: C28H41N9O10PS2·Na. Mole weight: 781.8. | |
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