BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cabazitaxel N-1 | Cabazitaxel N-1 is an impurity of Cabazitaxel, a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. Synonyms: 5-((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-12-(benzoyloxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl) 3-(tert-butyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyloxazolidine-3,5-dicarboxylate. CAS No. 1354900-66-5. Molecular formula: C53H63NO15. Mole weight: 954.07. |  |
| Cabazitaxel N-3 | Cabazitaxel N-3 is an impurity of Cabazitaxel, a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. CAS No. 859498-31-0. Molecular formula: C57H61Cl6NO19. Mole weight: 1276.81. | |
| Cabergoline | Cabergoline is a lysergic acid amide derivative and a potent dopamine D2 receptor agonist. It has been used for monotherapy of Parkinson's disease in the early phase. It has a direct inhibitory effect on pituitary lactotroph (prolactin) cells. It acts on dopamine receptors in lactophilic hypothalamus cells to suppress prolactin production in the pituitary gland. It has been used as a first-line agent in the management of prolactinomas due to its higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine. It is developed by Johnson & Johnson. It has been approved the listing. Uses: Cabergoline has been used for monotherapy of parkinson's disease in the early phase. it has been used as a first-line agent in the management of prolactinomas. Synonyms: CG-101; FCE-21336; CG 101; FCE 21336; CG101; FCE21336; Cabaser; Cabaseril; 6-Allyl-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)ergoline-8-carboxamide; (8-Beta)-(2-propenyl); n-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-ergoline-8-carboxamide; Cabergolinum; (8β)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-ergoline-8-carboxamide. Grade: >98%. CAS No. 81409-90-7. Molecular formula: C26H37N5O2. Mole weight: 451.60. | |
| Cabergoline Impurity A | 6-Allyl-8β-carboxyergoline is a metabolite of cabergoline which is a dopamine D2-receptor agonist. Synonyms: (8β)-6-(2-Propen-1-yl)-ergoline-8-carboxylic Acid; 6-(2-Propenyl)dihydrolysergic Acid; FCE 21589. Grade: > 95%. CAS No. 81409-74-7. Molecular formula: C18H20N2O2. Mole weight: 296.37. | |
| Cabergoline Impurity B | European Pharmacopoeia (EP) Impurity B of Cabergoline. Synonyms: (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propen-1-yl)-ergoline-1,8-dicarboxamide; (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propenyl)-ergoline-1,8-dicarboxamide; Cabergoline EP Impurity B. Grade: > 95%. CAS No. 166533-36-4. Molecular formula: C26H37N5O2. Mole weight: 451.62. | |
| Cabergoline Impurity C | European Pharmacopoeia (EP) Impurity C of Cabergoline. Synonyms: (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-N8-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-ergoline-1,8-dicarboxamide; (8β)-N8-[3-(dimethylamino)propyl]-N1-ethyl-N8-[(ethylamino)carbonyl]-6-(2-propenyl)--ergoline-1,8-dicarboxamide. Grade: > 95%. CAS No. 126554-50-5. Molecular formula: C29H42N6O3. Mole weight: 522.7. | |
| Cabergoline Impurity D | A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum. Synonyms: N-[3-(Dimethylamino)propyl]-6-(2-propen-1-yl)-(8β)-ergoline-8-carboxamide; (5R,8R,10R)-6-Allyl-N-[3-(dimethylamino)propyl]ergoline-8-carboxamide; FCE 21590. Grade: > 95%. CAS No. 85329-86-8. Molecular formula: C23H32N4O. Mole weight: 380.54. | |
| Cabotegravir (GSK744, GSK1265744) | Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2. Uses: Hiv integrase inhibitors. Synonyms: S/GSK1265744; S/GSK 1265744; S/GSK-1265744; GSK744; GSK-744; GSK 744; Cabotegravir. Grade: >98%. CAS No. 1051375-10-0. Molecular formula: C19H17F2N3O5. Mole weight: 405.35. | |
| Cabozantinib Des-O-fluoroaniline | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic acid; Cabozantinib Impurity 03. CAS No. 849217-77-2. Molecular formula: C22H20N2O6. Mole weight: 408.40. | |
| Cabozantinib N-oxide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 4-(4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6,7-dimethoxyquinoline 1-oxide; 1,1-Cyclopropanedicarboxamide, N-(4-((6,7-dimethoxy-1-oxido-4-quinolinyl)oxy)phenyl)-N'-(4-fluorophenyl)-; Cabozantinib Impurity 04. CAS No. 1621681-63-7. Molecular formula: C28H24FN3O6. Mole weight: 517.51. | |
| Cabozantinib S-malate | Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: Cabozantinib malate; cabozantinib (S)-malate; Cabometyx; 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2S)-2-hydroxybutanedioic acid. Grade: >98%. CAS No. 1140909-48-3. Molecular formula: C28H24FN3O5.C4H6O5. Mole weight: 635.59. | |
| CaCCinh-A01 | CaCCinh-A01 has been found to be a calcium-activated chloride channel (CaCC) inhibitor, wich IC50 ~ 10 μM. Synonyms: CaCCinh-A01; CaCC(inh)-A01, TMEM16 Blocker I. 6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid. Grade: ≥99% by HPLC. CAS No. 407587-33-1. Molecular formula: C18H21NO4S. Mole weight: 347.43. | |
| Cadalin | Cadalin is a potent antiviral compound widely used in the biomedical industry for the research of influenza A and B viruses. Its active ingredient, Oseltamivir, inhibits the neuraminidase enzyme, preventing the release of viruses from infected cells. Synonyms: Naphthalene, 1,?6-dimethyl-4-(1-methylethyl)?-. Grade: > 95%. CAS No. 483-78-3. Molecular formula: C15H18. Mole weight: 198.31. | |
| Cadazolid | Cadazolid, also referred to ACT-179811, is a new fluoroquinolone-oxazolidinone antibiotic with potent activity against Clostridium difficile. Synonyms: ACT-179811; ACT 179811; ACT179811. CAS No. 1025097-10-2. Molecular formula: C29H29F2N3O8. Mole weight: 585.55. | |
| CADD522 | CADD522 is a small-molecule inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with IC50 of 10 nM. CADD522 reduced RUNX2-mediated increases in glucose uptake and decreased the level of CBF-β and RUNX2 phosphorylation at the S451 residue. Synonyms: 3-([(3,4-Dichlorophenyl)amino]carbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid. CAS No. 199735-88-1. Molecular formula: C15H13Cl2NO3. Mole weight: 326.17. | |
| Cadein1 | Cadein1 leads to a G2/M delay and caspase-dependent apoptosis in cancer cells with non-functional p53. Synonyms: Cadein1; HY-131143; CS-0129442. Molecular formula: C33H48F2INO2. Mole weight: 655.64. | |
| cADP-Ribose (cADPR) Ammonium Salt | Cyclic ADP-ribose ammonium is a potent calcium-mobilized second messenger synthesized from NAD+ by ADP-ribosyl cyclase. It increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and extracellular influx through the opening of TRPM2 channels. Synonyms: cADP-Ribose Ammonium Salt; cADPR Ammonium Salt; cyclic ADP-ribose ammonium salt; Cyclic Adenosine Diphosphate Ribose ammonium salt; Cyclic adenosine 5'-diphosphate ribose ammonium salt. Grade: 90%. Molecular formula: C15H21N5O13P2.x(NH3). Mole weight: 541.30 (free base). | |
| Cafedrine | Cafedrine is a medication that acts as a vasopressor and cardiac stimulant. It is used primarily to treat hypotension (low blood pressure) and shock. Cafedrine acts by stimulating the release of norepinephrine (noradrenaline) from nerve endings and also by directly stimulating alpha-adrenergic receptors in blood vessels. This results in vasoconstriction (narrowing of blood vessels), which increases blood pressure. Synonyms: (-)-Cafedrine; 7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline; Brn 0583473; L-Cafedrine; 3,7-Dihydro-7-[2-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione; 7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; Cafedrin. Grade: ≥95%. CAS No. 58166-83-9. Molecular formula: C18H23N5O3. Mole weight: 357.41. | |
| Cafedrine hydrochloride | Cafedrine hydrochloride is a medication that acts as a vasopressor and cardiac stimulant. It is used primarily to treat hypotension (low blood pressure) and shock. Cafedrine acts by stimulating the release of norepinephrine (noradrenaline) from nerve endings and also by directly stimulating alpha-adrenergic receptors in blood vessels. This results in vasoconstriction (narrowing of blood vessels), which increases blood pressure. Synonyms: (-)-Cafedrine hydrochloride; 7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline hydrochloride; Brn 0583473 hydrochloride; L-Cafedrine hydrochloride; 3,7-Dihydro-7-[2-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione hydrochloride; 7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione hydrochloride; Cafedrin hydrochloride; Cafedrine HCl; Akrinor; L-Net. Grade: ≥95%. CAS No. 3039-97-2. Molecular formula: C18H23N5O3.ClH. Mole weight: 393.87. | |
| Caffeic acid 3-O-b-D-glucopyranoside | Caffeic acid 3-O-b-D-glucopyranoside, an organic constituent abundant in diverse flora, exhibits promise as an antioxidant, anti-inflammatory, and anticancer agent. Within the realm of biomedical research, this compound assumes an integral role in the creation of therapeutics targeting cancer, cardiovascular ailments, and neurodegenerative afflictions. Additionally, its incorporation in skincare and cosmetic merchandise is advantageous due to its rejuvenating attributes and ability to safeguard the skin from harm. Synonyms: 3-[3-(b-D-Glucopyranosyloxy)-4-hydroxyphenyl]-2-propenoic acid; 3-(b-D-Glucopyranosyloxy)-4-hydroxy-cinnamic acid; 3-(b-D-Glucopyranosyloxy)-4-hydroxycinnamic acid. CAS No. 24959-81-7. Molecular formula: C15H18O9. Mole weight: 342.30. | |
| Caffeic acid-pYEEIE | Caffeic acid-pYEEIE has been found to be a phosphopeptide ligand. Synonyms: N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-glutamic acid. Grade: ≥95% by HPLC. CAS No. 507471-72-9. Molecular formula: C39H50N5O19P. Mole weight: 923.82. | |
| Caffeidine Acid | Caffeidine Acid is a degradation compound of Caffeine, which is a central nervous system (CNS) stimulant used as a cognitive enhancer to increase alertness and attention performance. Synonyms: Caffeidinecarboxylic Acid; 1-Methyl-4-[methyl[(methylamino)carbonyl]amino]-1H-imidazole-5-carboxylic Acid; 4-(1,3-Dimethylureido)-1-methyl-1H-imidazole-5-carboxylic Acid. Grade: 96%. CAS No. 54536-15-1. Molecular formula: C8H12N4O3. Mole weight: 212.21. | |
| Caffeidine Acid Sodium Salt | Caffeidine Acid Sodium Salt is one of Caffeine impurities. Caffeine is a CNS stimulant. Alkaloid, purified from plants of Coffea genus, Rubiaceae. Synonyms: 1-Methyl-4-[methyl[(methylamino)carbonyl]amino]-1H-Imidazole-5-carboxylic Acid Sodium Salt; Caffeidinecarboxylic Acid Sodium Salt; 4-(1,3-dimethylureido)-1-methyl-1H-imidazole-5-carboxylate, sodium salt (1:1); Caffeine Impurity 1 Sodium Salt. Molecular formula: C8H11N4O3.Na. Mole weight: 234.19. | |
| Caffeine Impurity 1 Ammonium Salt | Caffeine Impurity 1 Ammonium Salt is one of Caffeine impurities. Caffeine is a CNS stimulant. Alkaloid, purified from plants of Coffea genus, Rubiaceae. Synonyms: 4-(1,3-dimethylureido)-1-methyl-1H-imidazole-5-carboxylate, ammonium salt (1:1). Molecular formula: C8H11N4O3.NH4. Mole weight: 229.24. | |
| Caffeine Impurity 1 (Sodium 4-[N-Methyl-N-(N-Methylaminocarbonyl)amino]-1-methylimidazole-5-Carboxylate) | Caffeidine Acid is a potential degradation product from the hydrolysis of Caffeine under alkaline environment. Synonyms: 1-Methyl-4-[methyl[(methylamino)carbonyl]amino]-1H-Imidazole-5-carboxylic Acid Sodium Salt; Caffeidinecarboxylic Acid Sodium Salt. Grade: > 95%. Molecular formula: C8H11N4O3. Na. Mole weight: 211.20 22.99. | |
| Caffeine Impurity 5 | Caffeine Impurity 5 is one of Caffeine impurities. Caffeine is a CNS stimulant. Alkaloid, purified from plants of Coffea genus, Rubiaceae. Synonyms: (1,3-dimethyl-2,6,8-trioxo-1,2,3,6,8,9-hexahydro-purin-7-yl)-acetic acid; (8-Hydroxy-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)-acetic acid; 1,2,3,6,8,9-hexahydro-1,3-dimethyl-2,6,8-trioxo-7H-purine-7-acetic Acid. Grade: 98%. CAS No. 10184-35-7. Molecular formula: C9H10N4O5. Mole weight: 254.20. | |
| Caffeine Impurity B | An impurity of Dyphylline which is a mainstay of therapy in some patients with acute and chronic obstructive airway disease. Synonyms: 6-Amino-5-formamido-1,3-dimethyl-uracil; 1,3-Dimethyl-4-amino-5-(formylamino)uracil; 6-Amino-1,3-dimethyl-5-(formylamino)pyrimidine-2,4-dione; N-(6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-formamide; N-(6-Amino-1,3-dimethyl-2,4-dioxo. Grade: > 95%. CAS No. 7597-60-6. Molecular formula: C7H10N4O3. Mole weight: 198.18. | |
| Caffeine Impurity C (Isocaffeine) | Isocaffeine is an impurity of Caffeine, a xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Synonyms: 3,9-Dihydro-1,3,9-trimethyl-1H-purine-2,6-dione; 1,3,9-Trimethylxanthine; 9-Methyltheophylline; NSC 28332; EP Impurity C for Caffeine. Grade: > 95%. CAS No. 519-32-4. Molecular formula: C8H10N4O2. Mole weight: 194.19. | |
| Caffeine Impurity E | Caffeidine is an impurity of Caffeine (C080100), a xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeidine have also shown inhibitory activity towards cyclic nucleotide phosphodiesterases. Synonyms: Caffeidine; 1H-Imidazole-5-carboxamide, N,?1-dimethyl-4-(methylamino)?-, hydrochloride. Grade: > 95%. CAS No. 20041-90-1. Molecular formula: C7H12N4O. Mole weight: 168.2. | |
| Caffeine Impurity F | Paraxanthine is a metabolite of caffeine, and also acts as an inhibitor of phosphodiesterase 9 (PDE9) and an antagonist of adenosine receptors A1 and A2 (Kis = 35 and 22 μM, respectively in equine forebrain tissues). Synonyms: 1,7-Dimethylxanthine; P-Xanthine; Xanthine, 1,7-dimethyl-; 3,7-Dihydro-1,7-dimethyl-1H-purine-2,6-dione. Grade: > 95%. CAS No. 611-59-6. Molecular formula: C7H8N4O2. Mole weight: 180.17. | |
| CAL-130 | CAL-130 is a potent and selective PI3K gamma and delta inhibitor with potential anticancer activity. Constitutive phosphoinositide 3-kinase (PI3K)/Akt activation is common in T cell acute lymphoblastic leukemia (T-ALL). Although four distinct class I PI3K isoforms (α, β, γ, δ) could participate in T-ALL pathogenesis, none has been implicated in this process. In the absence of PTEN phosphatase tumor suppressor function, PI3Kγ or PI3Kδ alone can support leukemogenesis, whereas inactivation of both isoforms suppressed tumor formation. The reliance of PTEN null T-ALL on the combined activities of PI3Kγ/δ was further demonstrated by the ability of a dual inhibitor to reduce disease burden and prolong survival in mice as well as prevent proliferation and promote activation of proapoptotic pathways in human tumors. CAL-130 may be useful for therapy for T-ALL. Synonyms: CAL130; CAL 130. Grade: >98%. CAS No. 1431697-74-3. Molecular formula: C23H22N8O. Mole weight: 426.47. | |
| CAL-130 Hydrochloride | In the absence of PTEN phosphatase tumor suppressor function, PI3Kγ or PI3Kδ alone can support leukemogenesis, whereas inactivation of both isoforms suppressed tumor formation. The reliance of PTEN null T-ALL on the combined activities of PI3Kγ/δ was further demonstrated by the ability of a dual inhibitor to reduce disease burden and prolong survival in mice as well as prevent proliferation and promote activation of proapoptotic pathways in human tumors. Synonyms: CAL-130 Hydrochloride; CAL 130 Hydrochloride; CAL130 Hydrochloride; (S)-2-(1-((2-amino-9H-purin-6-yl)amino)ethyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one hydrochloride. Grade: >98%. CAS No. 1431697-78-7. Molecular formula: C23H23ClN8O. Mole weight: 462.93. | |
| CAL-130 Racemate | CAL-130 racemate is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that combined inhibition of PI3Kγ/δ as therapy for T cell acute lymphoblastic leukemia (T-ALL). Synonyms: CAL-130 Racemate; CAL 130 Racemate; CAL130 Racemate. Grade: >98%. CAS No. 474012-90-3. Molecular formula: C23H22N8O. Mole weight: 426.47. | |
| Calcifediol Impurity 1 | An impurity of Vitamin D3. Vitamin D3 is a type of vitamin D found to be effective in mediating intestinal calcium absorbtion and bone calcium metabolism. Vitamin D3 is used for the prevention and treatment of vitamin D deficiency and associated disease including rickets, and also used for familial hypophosphatemia, hypoparathyroidism and Fanconi syndrome. Synonyms: 9,10-Secocholesta-5(10),6,8-triene-3,25-diol, (3b,6Z)-. CAS No. 23357-18-8. Molecular formula: C27H44O2. Mole weight: 400.645. | |
| Calcifediol Intermediate | A derivative of vitamin D3 and an intermediate of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Molecular formula: C33H56O3Si. Mole weight: 528.891. | |
| Calcifediol monohydrate | Calcifediol monohydrate is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase. It can be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Uses: Bone density conservation agents. Synonyms: 25-Hydroxycholecalciferol monohydrate; 25-hydroxy Vitamin D3 monohydrate. Grade: >98%. CAS No. 63283-36-3. Molecular formula: C27H46O3. Mole weight: 418.65. | |
| Calcifediol Monohydrate EP Impurity A | Calcifediol Monohydrate EP Impurity A is a derivative of vitamin D3 and an impurity of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Synonyms: Calcifediol EP Impurity A; 9β,10α-cholesta-5,7-diene-3β,25-diol; 25-Hydroxylumisterol; 25-Hydroxyprovitamin D3. CAS No. 61585-29-3. Molecular formula: C27H44O2. Mole weight: 400.65. | |
| Calcifediol Monohydrate EP Impurity B | Calcifediol Monohydrate EP Impurity B is a derivative of vitamin D3 and an impurity of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Synonyms: Calcifediol EP Impurity B; 25-Hydroxyprovitamin D3; 25-Hydroxy-7-dehydrocholesterol; cholesta-5,7-diene-3β,25-diol; 7-Dehydro-25-hydroxycholesterol. CAS No. 22145-68-2. Molecular formula: C27H44O2. Mole weight: 400.65. | |
| Calcifediol Monohydrate EP Impurity C | Calcifediol Monohydrate EP Impurity C is a derivative of vitamin D3 and an impurity of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Synonyms: Calcifediol EP Impurity C; 25-Hydroxytachysterol 3; (6E)-9,10-secocholesta-5(10),6,8-triene-3β,25-diol; (3S,6E)-9,10-secocholesta-5(10),6,8-triene-3,25-diol. CAS No. 39932-44-0. Molecular formula: C27H44O2. Mole weight: 400.65. | |
| Calcifediol Monohydrate EP Impurity D | Calcifediol Monohydrate EP Impurity D is a derivative of vitamin D3 and an impurity of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Synonyms: Calcifediol EP Impurity D; 25-Hydroxycholecalciferol, 5-trans-; 5,6-trans-25-Hydroxy vitamin D3; 9,10-Secocholesta-5,7,10(19)-triene-3beta,25-diol; (3S,5E,7E)-9,10-secocholesta-5,7,10(19)-triene-3,25-diol. CAS No. 1233749-00-2. Molecular formula: C27H44O2. Mole weight: 400.65. | |
| Calcipotriene β-Isomer | Calcipotriene β-Isomer is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Molecular formula: C27H40O3. Mole weight: 412.62. | |
| Calcipotriol | Calcipotriol, a 1,25-Dihydroxyvitamin D3 analogue, is used as topical treatment for psoriasis. Uses: Dermatologic agents. Synonyms: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol; Calcipotriol; MC-903; Daivonex; Dovonex; Psorcutan; Calcipotriene. Grade: 95%. CAS No. 112965-21-6. Molecular formula: C27H40O3. Mole weight: 412.61. | |
| Calcipotriol EP Impurity A | A vitamin D3 analogue with similar effects. An impurity of Calcipotriol, an antipsoriatic. Synonyms: Impurity A of Calcipotriol; MC 1046; MC1046; MC-1046. Grade: >98%. CAS No. 126860-83-1. Molecular formula: C27H38O3. Mole weight: 410.59. | |
| Calcipotriol EP Impurity B | Calcipotriol EP Impurity B is an analogue of vitamin D3 and an isomer of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: (5Z,7Z,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol; (7Z)-Calcipotriene; (7Z)-calcipotriol; (5Z,7Z)-Calcipotriene; (1R,3S,Z)-5-(2-((1R,3aS,7aR,Z)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol; (1S,3R,5Z,7Z,22E,24S)-26,27-Cyclo-9,10-secocholesta-5,7,10,22-tetraene-1,3,24-triol; 1,3-Cyclohexanediol, 5-[(2Z)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-. Grade: ≥90%. CAS No. 2948288-30-8. Molecular formula: C27H40O3. Mole weight: 412.60. | |
| Calcipotriol EP Impurity C | Calcipotriol EP Impurity C, the trans-isomeric impurity of Calcipotriene, is an analogue of vitamin D3 which could be an agonist of vitamin D receptor. Synonyms: CS-M0059; CS M0059; CSM0059; (1a,3b,5E,7E,22E,24S)-24-Cyclopropyl-9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol. Grade: 95%. CAS No. 113082-99-8. Molecular formula: C27H40O3. Mole weight: 412.61. | |
| Calcipotriol EP Impurity D | An impurity of Calcipotriol, which is a ligand of VDR-like receptors. Synonyms: PRI 2202; PRI2202; PRI-2202; 24R-Calcipotriol; (24R)-Calcipotriene. Grade: 95%. CAS No. 112827-99-3. Molecular formula: C27H40O3. Mole weight: 412.6. | |
| Calcipotriol EP Impurity E | Calcipotriol EP Impurity E is an analogue of vitamin D3 and an isomer of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: rac-(5Z,7E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19)-triene-1α,3β,24-triol. Grade: 95%. Molecular formula: C27H42O3. Mole weight: 414.62. | |
| Calcipotriol EP Impurity F | An impurity of Calcipotriol, which is a ligand of VDR-like receptors. Synonyms: (1α,3β,5Z,7E,22E,24S)-24-cyclopropyl-1,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9,10-Secochola-5,7,10(19),22-tetraen-24-ol; (αS)-α-[(1E,3R)-3-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene. Grade: >98%. CAS No. 112875-61-3. Molecular formula: C39H68O3Si2. Mole weight: 641.13. | |
| Calcipotriol EP Impurity G | Calcipotriol EP Impurity G, of which the strucure is composed of two calcipotriol molecules, is an impurity of Calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: 24,24'-oxybis[(5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β-diol]. Molecular formula: C54H78O5. Mole weight: 807.19. | |
| Calcipotriol EP Impurity H | Calcipotriol EP Impurity H, of which the strucure is composed of two calcipotriol molecules, is an impurity of Calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: (5Z,7E,22E,24R)-24-cyclopropyl-24-[[(5Z,7E,22E,24S)-24-cyclopropyl-1α,3β-dihydroxy-9,10-secochola-5,7,10(19),22-tetraen-24-yl]oxy]-9,10-secochola-5,7,10(19),22-tetraene-1α,3β-diol. Molecular formula: C54H78O5. Mole weight: 807.19. | |
| Calcipotriol EP Impurity I | Calcipotriol EP Impurity I is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: (6S,7R,8R,22E,24S)-24-cyclopropyl-6,8:7,19-dicyclo-9,10-secochola-5(10),22-diene-1α,3β,24-triol; suprasterol of calcipotriol. Molecular formula: C27H40O3. Mole weight: 412.6. | |
| Calcipotriol Impurity 1 | (5E,24R)-Calcipotriene is an analog of (5E)-Calcipotriene ; the trans-isomeric impurity of Calcipotriene and a vitamin D3 analogue with antitumor effects. Synonyms: (1α,3β,5E,7E,22E,24R)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol; (1R,3S,E)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R,E)-5-Cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-. Grade: > 95%. CAS No. 112849-47-5. Molecular formula: C27H40O3. Mole weight: 412.62. | |
| Calcipotriol Impurity 2 | Calcipotriol Impurity 2 is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Molecular formula: C27H40O3. Mole weight: 412.62. | |
| Calcipotriol Intermediate 9 | Calcipotriol Intermediate 9 is an intermediate of calcipotriol synthesis. Calcipotriol is a vitamin D3 analogue used for psoriasis treatment. Synonyms: (2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one; (5E)-1,3-Bis-O-(tert-Butyldimethylsilyl)-24-oxo-calcipotriene. CAS No. 112849-17-9. Molecular formula: C39H66O3Si2. Mole weight: 639.11. | |
| Calcipotriol Monohydrate | Calcipotriol monohydrate is a synthetic vitamin D3 analogue with a high affinity for the vitamin D receptor. Synonyms: Calcipotriene monohydrate; Dovonex (TN). Grade: >98%. CAS No. 147657-22-5. Molecular formula: C27H42O4. Mole weight: 430.62. | |
| Calcitetrol | Calcitetrol is the hormonally active form of vitamin D with three hydroxyl groups. It increases blood calcium levels ([Ca2+]) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium, thus reducing the loss of calcium in the urine. It also stimulates release of calcium from bone by its action on the specific type of bone cells referred to as osteoblasts, causing them to release RANKL, which in turn activates osteoclasts. Synonyms: 1α, 24, 25-Trihydroxy VD3. Grade: >98%. CAS No. 72203-93-1. Molecular formula: C27H44O4. Mole weight: 432.64. | |
| Calcitonin | Calcitonin is a hormone produced by the parafollicular cells (C-cells) of the thyroid gland. It plays a crucial role in calcium homeostasis by lowering blood calcium levels, opposing the actions of parathyroid hormone (PTH), which increases calcium levels. Calcitonin achieves this by inhibiting osteoclast activity, reducing bone resorption, and decreasing calcium reabsorption in the kidneys. It is also involved in phosphate regulation, lowering blood phosphate levels. In clinical settings, calcitonin has been used to treat conditions such as hypercalcemia, Paget's disease of bone, and osteoporosis. Synonyms: Calcitrin; TCA; TCT; Thyrocalcitonin; Thyrocalcitonins. Grade: 95%. CAS No. 9007-12-9. | |
| Calcitonin (chicken) | Calcitonin (chicken) is a hormone that regulates calcium metabolism. It is produced by the ultimobranchial gland in chickens. Calcitonin (chicken) has been shown to suppress cell motility and bone resorption in neonatal rat osteoclasts. Additionally, it plays a role in calcium homeostasis in chickens, although its effects on bone metabolism appear to be different from those in mammals. Calcitonin (chicken) receptors are present in avian reproductive tissues and are involved in the eggshell calcification process. Synonyms: L-Prolinamide, L-cysteinyl-L-alanyl-L-seryl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-α-aspartyl-L-valylglycyl-L-alanylglycyl-L-threonyl-, cyclic (1→7)-disulfide; 2-L-Alanine-3-L-serine-26-L-aspartic acid-27-L-valine-29-L-alanine-calcitonin (salmon); Chicken calcitonin; Chicken thyrocalcitonin; Calcitonin, chicken; H-Cys-Ala-Ser-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 (Disulfide bridge: Cys1-Cys7). Grade: 95%. CAS No. 100016-62-4. Molecular formula: C145H240N42O46S2. Mole weight: 3371.84. | |
| Calcitonin Paralle Dimer | Calcitonin Paralle Dimer is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: 2[H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2] (inter-disulfide bridges between 1,1' and 7,7' cysteines). Molecular formula: C290H480N88O96S4. Mole weight: 6863.79. | |
| Calcitonin (salmon), acetate (1:1) | Calcitonin salmon, a calcium regulating hormone, has been shown to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: Calcitonin(salmon) Acetate; Salmon calcitonin-(1-32) Acetate; Salmon Thyrocalcitonin Acetate; H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2.CH3CO2H (Disulfide bridge: Cys1-Cys7); L-Cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide (1->7)-disulfide acetate salt. Grade: ≥95%. CAS No. 1789726-86-8. Molecular formula: C147H244N44O50S2. Mole weight: 3491.90. | |
| Calcitonin Salmon-[d10] | Calcitonin Salmon-[d10] is the labelled analogue of Calcitonin Salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu(D10)-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond between Cys1 and Cys7); Calcitonin Salmon D10 Impurity. Molecular formula: C145H230D10N44O48S2. Mole weight: 3441.96. | |
| Calcitonin (salmon) trifluoroacetate salt | Calcitonin is a peptide hormone that lowers blood calcium levels and inhibits bone resorption. The binding of salmon calcitonin to the human calcitonin receptor (CTR) is not modulated by receptor activity-modifying proteins (RAMPs), which influences affinity of human calcitonin to CTR. Salmon calcitonin binds to human CTR2 with IC50 values of 0.933, 0.224, 0.134, and 0.317 nM alone and with RAMP1, 2, or 3, respectively. Formulations containing salmon calcitonin have been used to treat hypercalcemia, bone destruction by osteoporosis, and Paget's disease. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2.TFA (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide (1->7)-disulfide trifluoroacetate salt; Salmon Calcitonin trifluoroacetate (salt). Grade: ≥95%. CAS No. 171052-37-2. Molecular formula: C145H240N44O48S2.xC2HF3O2. Mole weight: 3431.86 (free base). | |
| Calcitonin (swine) | Calcitonin (swine) is a polypeptide hormone that plays a significant role in regulating calcium homeostasis and bone metabolism. It is secreted by the parafollicular cells (C-cells) of the thyroid gland in pigs. Calcitonin inhibits osteoclast activity, thereby reducing bone resorption and lowering serum calcium levels. Additionally, it promotes calcium excretion by the kidneys, further aiding in calcium regulation. In swine, calcitonin is involved in protecting the skeleton from excessive bone mineral loss during periods of high calcium demand, such as lactation. This protective effect is primarily mediated through the inhibition of osteoclastic resorption. The hormone is also implicated in preventing postprandial hypercalcemia resulting from calcium absorption. Synonyms: L-Prolinamide, L-cysteinyl-L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-L-seryl-L-alanyl-L-tyrosyl-L-tryptophyl-L-arginyl-L-asparaginyl-L-leucyl-L-asparaginyl-L-asparaginyl-L-phenylalanyl-L-histidyl-L-arginyl-L-phenylalanyl-L-serylglycyl-L-methionylglycyl-L-phenylalanylglycyl-L-prolyl-L-α-glutamyl-L-threonyl-, cyclic (1→7)-disulfide; Calcitonin (pig); Thydrocalcit. Grade: 95%. CAS No. 12321-44-7. Molecular formula: C159H232N46O45S3. Mole weight: 3604.02. | |
| Calcitriol Derivatives | Calcitriol Derivatives is an analog of vitamin D3. Synonyms: 3-{[(1S,3R,5Z,7E)-1,25-Dihydroxy-9,10-secocholesta-5,7,10-trien-3-yl]oxy}propanenitrile; Propanenitrile, 3-[[(1R,3S,5Z)-3-hydroxy-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]cyclohexyl]oxy]-. CAS No. 2070009-24-2. Molecular formula: C30H47NO3. Mole weight: 469.70. | |
| Calcitriol EP Impurity A | 5,6-trans Calcitriol is an impurity of Calcitriol, which is the hormonally active form of vitamin D and is the active metabolite of vitamin D3. It is the trans isomer of Calcitriol. It is used as a control product to study calcitriol. Uses: Bone density conservation agents. Synonyms: trans-Calcitriol; 5,6-trans-Calcitriol; 1,25-Dihydroxy-5,6-trans-vitamin D3; (5E,7E)-9,10-secocholesta-5,7,10(19)-triene-1α,3β,25-triol; (1α,3β,5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; 1α,25-Dihydroxy-5,6-trans-vitamin D3. Grade: 98%. CAS No. 73837-24-8. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| Calcitriol EP Impurity B | Calcitriol EP Impurity B is the hormonally active form of vitamin D, and Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR), which inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. Synonyms: Epi-Calcitriol; 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol; Impurity B of Calcitriol; 1β-Calcitriol; 1-epi-Calcitriol; (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1β,3β,25-triol. Grade: >98%. CAS No. 66791-71-7. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| Calcitriol EP Impurity C | Calcitriol EP Impurity C is an impurity of Calcitriol, which is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Synonyms: Triazoline Adduct of pre-Calcitriol; pre-Calcitriol PTAD Adduct (Mixture of Diastereomers); Impurity C of Calcitriol (6aR,7R,9aR)-11-[(3S,5R)-3,5-dihydroxy-2-methylcyclohex-1-enyl]-7-[(1R)-5-hydroxy-1,5-dimethylhexyl]-6a-methyl-2-phenyl-5,6,6a,7,8,9,9a,11-octahydro-1H,4aH-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione. Grade: >98%. CAS No. 86307-44-0. Molecular formula: C35H49N3O5. Mole weight: 591.78. | |
| Calcitriol Impurity 1 | Calcitriol Impurity 1 is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Molecular formula: C27H44O3. Mole weight: 416.645. | |
| Calcitriol Intermediate | A derivative of vitamin D3 and an intermediate of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Synonyms: (5R)-ethyl-5-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-2-methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)hexanoate. CAS No. 169900-32-7. Molecular formula: C39H70O4Si2. Mole weight: 659.15. | |
| Calcitroic Acid | Calcitroic Acid is a derivative of vitamin D3 and an impurity of calcitriol. Calcitriol is a metabolite of vitamin D, and it increases the level of calcium in the blood. Synonyms: 1H-Indene-1-propanoic acid, 4-[(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-β,7a-dimethyl-, (βR,1R,3aS,4E,7aR)-; (βR,1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-Dihydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-β,7a-dimethyl-1H-indene-1-propanoic acid; 24-Nor-9,10-secochola-5,7,10(19)-trien-23-oic acid, 1,3-dihydroxy-, (1α,3β,5Z,7E)-; 1α-Hydroxycalcioic acid; MC 1235; 1alpha-Hydroxy-23-carboxytetranorvitamin D. Grade: >95%. CAS No. 71204-89-2. Molecular formula: C23H34O4. Mole weight: 374.52. | |
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