BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-Br-2',3',6'-TAc-Guo | 8-Br-2',3',6'-TAc-Guo is a bioactive compound, used for studying bacterial and viral afflictions by impeding the proliferation of malignant cells. CAS No. 16717-46-0. Molecular formula: C16H18N6O8Br. Mole weight: 488.6. |  |
| 8-Br-2'-O-Me-cAMP | 8-Br-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF without affecting protein kinase A. Alternative Names: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 612513-13-0. Molecular formula: C11H12BrN5O6P · Na. Mole weight: 444.1. | |
| 8-Br-2'-O-Me-cAMP-AM | 8-Br-2'-O-Me-cAMP-AM is a precursor of 8-Br-2'-O-Me-cAMP, the specific Epac agonist. 8-Br-2'-O-Me-cAMP is released after the metabolism of 8-Br-2'-O-Me-cAMP-AM by esterases. Alternative Names: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C14H17BrN5O8P. Mole weight: 494.2. | |
| 8-Br-2'-O-Me-cGMP | 8-Br-2'-O-Me-cGMP is an analogue of cGMP that does not activate both protein kinase G and Epac. It is often used as an inactive control versus 8-Br-cGMP. Alternative Names: 8- Bromo- 2'- O- methylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C11H12BrN5O7P · Na. Mole weight: 460.1. | |
| 8-Br-2'-O-Me-Guo | 8-Br-2'-O-Me-Guo is an exceptional antiviral compound massively employed within the biomedical sector, showcasing Inhibitory efficacy in the research of diverse viral maladies such as influenza and respiratory syncytial virus. Alternative Names: 8- Bromo- 2'- O- methylguanosine. CAS No. 847649-49-4. Molecular formula: C11H14N6O6Br. Mole weight: 376.2. | |
| 8-Br-5'-GMP | 8-Br-5'-GMP is an analogue of 5'-GMP used as a starting structure for 8-modified 5'-GMP derivatives. Alternative Names: 8- Bromoguanosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 21870-09-7. Molecular formula: C10H13BrN5O8P (free acid). Mole weight: 442.1 (free acid). | |
| 8-Br-cAMP | 8-Br-cAMP, a synthetic cyclic adenosine monophosphate (cAMP) analog, demonstrates versatile potential in medical and biological sciences. From inhibiting platelet aggregation and inducing cellular differentiation, to regulating gene expression and advancing therapeutic research - its applications span across cancer, cardiovascular, and endocrine disorders. Its potential for enhancing cellular signaling and invigorating treatment research sets it apart as a tool for shaping the future of life sciences. Uses: Reprogramming. Alternative Names: 8-Br-cAMP; BCAMP; 8-Bromo-cyclic AMP; 8-Bromoadenosine 3',5'-cyclic monophosphate; 8-bromo-cAMP; 8-Bromo-cyclic 3',5'-AMP; 8-Bromoadenosine cyclic 3',5'-phosphate; Cyclic 8-bromoadenosine 3',5'-monophosphate; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; 8-Bromoadenosine 3',5'-monophosphate; 8-bromo-3',5'-cyclic AMP; Cyclic AMP, 8-bromo; 5QO1UW05Q5; CHEBI:64211; MFCD00075580; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate); 8-bromoadenosine 3',5'-(hydrogen phosphate); (4AR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide1111. Grades: 0.98. CAS No. 23583-48-4. Molecular formula: C10H11BrN5O6P. Mole weight: 408.1. | |
| 8-Br-c-diGMP | 8-Br-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used for binding studies and precursor for further modifications with spacers or labels. Alternative Names: 8- Bromo- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23BrN10O14P2 (free acid). Mole weight: 769.3 (free acid). | |
| 8-Br-cGMP | 8-Br-cGMP is a stimulator of cGMP dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cGMP agonist). Compared to cGMP, it has a superior stability. Alternative Names: 8- Bromoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 51116-01-9. Molecular formula: C10H10BrN5O7P · Na. Mole weight: 446.1. | |
| 8-Br-dA-CE Phosphoramidite | 8-Br-dA-CE Phosphoramidite is a valuable compound used in compound for the research and development of DNA and RNA oligonucleotides. It acting as a building block during the solid-phase research and development of modified DNA and RNA strands, enabling the incorporation of the 8-bromodeoxyadenosine (8-Br-dA) nucleoside. These modified nucleotides find applications in various research areas, including drug discovery, genetic engineering is and diagnostics. Alternative Names: 5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-bromo-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 207906-54-5. Molecular formula: C43H52N8O6PBr. Mole weight: 887.81. | |
| 8-Br-dGTP | 8-Br-dGTP is an analogue of dGTP used for receptor mapping studies and a starting structure for 8-modified dGTP derivatives. Alternative Names: 8- Bromo- 2'- deoxyguanosine- 5'- O- triphosphate. Grades: ≥ 95% by HPLC. CAS No. 66891-23-4. Molecular formula: C10H15BrN5O13P3 (free acid). Mole weight: 586.1 (free acid). | |
| 8-Bromo-2',3',5'-tri-O-acetyladenosine | 8-Bromo-2',3',5'-tri-O-acetyladenosine is a potent and selective inhibitor to study the role of adenosine receptors in various diseases, such as cancer, cardiovascular disorders and inflammatory conditions. It has the ability to modulate adenosine signaling pathways. Alternative Names: 8-Bromo-adenosine 2',3',5'-Triacetate; 2',3',5'-Tri-O-acetyl-8-bromoadenosine; NSC 79212. Grades: 95%. CAS No. 31281-86-4. Molecular formula: C16H18BrN5O7. Mole weight: 472.25. | |
| 8-Bromo-2',3',5'-tri-O-acetylguanosine | 8-Bromo-2',3',5'-tri-O-acetylguanosine is an exquisitely intricate and exceptionally useful biochemical compound, tailored with intrinsic antiviral capabilities. It is revered for its profound potential in dissecting the intricate dynamics of viral RNA-dependent RNA polymerases. Alternative Names: 8-Bromo-guanosine 2',3',5'-Triacetate; 2',3',5'-Tri-O-acetyl-8-bromoguanosine; NSC 174056; NSC 79210. Grades: 98%. CAS No. 15717-45-0. Molecular formula: C16H18BrN5O8. Mole weight: 488.25. | |
| 8-Bromo-2',5'-pAp | 8-Bromo-2',5'-pAp, a nucleotide analog, is widely applied as a substrate in enzymatic assays to explore RNA polymerase and RNA ligase abilities. Its versatility extends to the development of modified RNA molecules that serve as valuable tools in numerous biomedical fields. These applications include gene therapy for malignancies and genetic dysfunctions. Alternative Names: (8Br-2',5'-pAp); 8-Bromo-adenosine-2',5'-bisphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14BrN5O10P2 (free acid). Mole weight: 506.10 (free acid). | |
| 8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a cutting-edge synthetic compound based on guanosine, effectively incorporating 8-bromo modification and DMF-5'-O-DMT protection into guanosine residuals while carrying out oligonucleotide research and development. Alternative Names: 5'-Dimethoxytrityl-N2-dimethylaminomethylidene-8-bromo-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-Br-dG-CE Phosphoramidite; 8-Bromo-N2-DMF-5'-O-DMT-2'-deoxyguanosine 3'-CE phosphoramidite. CAS No. 198080-37-4. Molecular formula: C43H52N8O7PBr. Mole weight: 903.9. | |
| 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is an imperative compound, serving as an indispensable phosphorylation recompound engendering the amalgamation of oligonucleotides. Its pervasive utilization in the research of pharmacological exploration, primarily within the domain of nucleotide-based therapeutics spanning antisense oligonucleotides and siRNA. Alternative Names: 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-D-adenosine 3'-CE phosphoramidite; 8-Bromo-N6-DMF-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite. Molecular formula: C43H52BrN8O6P. Mole weight: 887.82. | |
| 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine | 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine is a key compound used in biomedical research for studying DNA enhancement and repair. It is primarily utilized in the development of antiviral drugs and therapies targeting viral DNA replication as well as in understanding the mechanisms underlying cell signaling pathways involved in cancer progression and autoimmune diseases. Alternative Names: 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxy-guanosine; 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine. Molecular formula: C22H40BrN5O4Si2. Mole weight: 574.66. | |
| 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine | 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine is an exceptionally influential compound integral to the research of investigating nucleosides, DNA enhancement and the development of antiviral / anticancer drugs. Alternative Names: 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxy-guanosine; 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine. Molecular formula: C29H46BrN5O4Si2. Mole weight: 664.78. | |
| 8-Bromo-3'-deoxy-3'-fluoroguanosine | 8-Bromo-3'-deoxy-3'-fluoroguanosine, an intriguing biomedical compound, holds immense potential in the realm of antiviral drug research and development. Its proven efficacy against formidable viruses such as herpes simplex and human immunodeficiency virus (HIV) fuels scientific curiosity. By delving into the enzymatic activities, mechanisms, and inhibition of viral replication, this compound serves as a vital tool driving progress in the field of antiviral therapeutics. Alternative Names: 2-amino-8-bromo-9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one. Grades: ≥95%. CAS No. 847649-50-7. Molecular formula: C10H11BrFN5O4. Mole weight: 364.13. | |
| 8-Bromo-3'-deoxy-3'-fluorotoyocamycin | 8-Bromo-3'-deoxy-3'-fluorotoyocamycin is a potent compound used in the research of various cancers and viral infections. Its mechanism of action involves inhibiting nucleic acid enhancement, leading to the suppression of tumor growth and viral replication. CAS No. 2095417-57-3. Molecular formula: C12H11BrFN5O3. Mole weight: 372.15. | |
| 8-Bromo-3'-deoxyguanosine | 8-Bromo-3'-deoxyguanosine is a remarkable and robust antiviral compound, finding extensive application in research of viral infections, especially those of DNA origin. Alternative Names: 2-amino-8-bromo-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one. Grades: ≥95%. CAS No. 847649-68-7. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine | 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine is a remarkable pharmaceutical compound with anti-inflammatory and immunomodulatory attributes. Potential applications include the research of various inflammatory ailments like rheumatoid arthritand asthma. Alternative Names: 8-Bromo-5'-O-(4-cyanobenzyl)-2',3'-di-O-isopropylidene adenosine; 4-[[(3aR,4R,6R,6aR)-4-(6-amino-8-bromopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxymethyl]benzonitrile; Adenosine, 8-bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-O-(1-methylethylidene)-; 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-O-(1-methylethylidene)adenosine; 4-((((3AR,4R,6R,6aR)-6-(6-amino-8-bromo-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methoxy)methyl)benzonitrile. Grades: ≥95%. CAS No. 1134156-53-8. Molecular formula: C21H21BrN6O4. Mole weight: 501.33. | |
| 8-Bromo-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-2'-deoxyadenosine | 8-Bromo-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-2'-deoxyadenosine, a chemical compound utilized in the production of antiviral and anticancer drugs, has been found to selectively impede the replication of herpes simplex virus and stunt the expansion of cancer cells by hindering their DNA synthesis. Its specificity in targeting these entities makes it a valuable player in the medical field. Its multifaceted properties offer advancements in the development of novel treatments. CAS No. 207906-53-4. Molecular formula: C34H35BrN6O5. Mole weight: 687.60. | |
| 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine | 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine, renowned for its unparalleled efficacy, stands as an indispensable entity within the illustrious biomedical realm. Revered for its unrivaled specificity, this miraculous compound has revolutionized the field by combatting DNA viruses with remarkable prowess. Its potency is particularly evident in its success against the notorious herpes simplex virus (HSV) and hepatitis B virus (HBV). Grades: ≥ 97%. CAS No. 204582-53-6. Molecular formula: C34H35BrN6O6. Mole weight: 703.59. | |
| 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine | 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine is an innovative compound, holding immense potential in studying a range of viral infections, with its primary focus lying on DNA viruses. Molecular formula: C22H38BrN5O5Si2. Mole weight: 588.64. | |
| 8-Bromo-9-(b-D-xylofuranosyl)guanine | 8-Bromo-9-(b-D-xylofuranosyl)guanine is an extraordinary antiviral compound bestowed with remarkable potentiality for research of viral infections, specifically focused on herpes viruses. By selectively concentrating on the viral DNA polymerase, it effectively restrains viral DNA enhancement. Alternative Names: 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-β-D-xylofuranosyl-; 2-amino-8-bromo-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one; 8-bromguanosine; 2-Amino-8-bromo-9-(β-D-xylofuranosyl)-1,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 1212650-12-8. Molecular formula: C10H12BrN5O5. Mole weight: 362.14. | |
| 8-Bromoadenosine | 8-Bromoadenosine is an adenosine binding inhibitor. 8-Bromoadenosine is a modified nucleoside with a bromine atom at the 8-position of the adenine base. It is used in biochemical research to study nucleic acid structure and function, and to investigate interactions between nucleic acids and proteins. Alternative Names: 8-Bromo-ribo Adenosine; 6-Amino-8-bromopurine Riboside; NSC 79213; 8-Bromo Adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Bromoadenosine; 8-Bromo-adenosine; 8-Bromoadenine-9-β-D-ribofuranoside. Grades: ≥97% by HPLC. CAS No. 2946-39-6. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromoadenosine 3',5'-Cyclic Monophosphothioate Sp-Isomer Sodium Salt | 8-Bromoadenosine 3',5'-Cyclic Monophosphothioate Sp-Isomer Sodium Salt is an activator of cAMP-dependent PKA. Alternative Names: 1573115-90-8; Rp-8-bromo-Cyclic AMPS (sodium salt); 8-Bromoadenosine 3',5'-cyclic monophosphothiaoate, Sp-isomer sodium salt; Rp-8-bromo-Cyclic AMPS; 127634-20-2; Sp-8-bromo-Cyclic AMPS (sodium salt); sodium; (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol; 8-Bromoadenosine3',5'-CyclicMonophosphothioateSp-IsomerSodiumSalt; 8-bromo-adenosinecyclic3',5'-[hydrogen[P(R)]-phosphorothioate],monosodiumsalt; Rp-8-bromo-Cyclic AMPS sodium salt; Rp-8-Br-cAMPS; Rp-8-bromo-cAMPS; 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer; Sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-sulfanylidene-hexahydro-2|E-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate; Sodium [(2R,4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-2|E-furo[3,2-d][1,3,2]dioxaphosphinin-2-yl]sulfanide. CAS No. 1573115-90-8. Molecular formula: C10H10BrN5NaO5PS. Mole weight: 446.15. | |
| 8-Bromoadenosine 5'-Triphosphate Sodium Salt | 8-Bromoadenosine 5'-Triphosphate Sodium Salt is a reagent required for the characterization (stoichiometry, geometry, and stability constant) of ATP:Fe(II) complex. Alternative Names: 8-bromo-adenosine-5'-triphosphate, sodium salt; 8-Br-ATP, Sodium Salt; 8-Bromo-adenosine 5'-(Tetrahydrogen triphosphate) Sodium Salt; Adenosine 5'-(tetrahydrogen triphosphate), 8-bromo-, sodium salt; 8-Bromo-ATP sodium salt. Grades: ≥95% by HPLC. CAS No. 81035-56-5. Molecular formula: C10H15BrN5O13P3 (free acid). Mole weight: 586.08 (free acid). | |
| 8-Bromo-ADP | 8-Bromo-ADP is a remarkable effector on purinergic receptors, which play vital roles in numerous intricate intracellular signaling cascades. This compound offering an invaluable avenue to probe the intricate repercussions of purinergic receptor activation on diverse cellular functionalities. Alternative Names: (8Br-ADP); 8-Bromo-adenosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 23600-16-0. Molecular formula: C10H14N5O10P2Br (free acid). Mole weight: 506.10 (free acid). | |
| 8-Bromo-AMP | 8-Bromo-AMP, a pharmaceutical compound widely employed in the biomedical sector, holds significant importance in the exploration and management of diverse diseases. As a derivative of adenosine monophosphate (AMP), it possesses altered characteristics that play a pivotal role in cellular metabolism and signaling. Moreover, owing to its utilization in signal transduction pathway investigations and assessment of adenylyl cyclase activation effects, 8-Bromo-AMP showcases its versatility. Alternative Names: (8Br-AMP); 8-Bromo-adenosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 23567-96-6. Molecular formula: C10H13BrN5O7P (free acid). Mole weight: 426.12 (free acid). | |
| 8-Bromo-AP2 (Nic) | 8-Bromo-AP2 (Nic) unlocks the potential for therapeutic intervention in multiple neurological disorders, including Alzheimer's disease and nicotine addiction, thanks to its potent and selective inhibitory effects on the nicotinic acetylcholine receptor. In addition to its clinical applications, this compound serves as a research tool for the in-depth study of nicotinic receptors within the complex biological framework of the brain. Alternative Names: (8Br-AP2(Nic)); Nicotinamide 8-bromo-adenine dinucleotide, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C21H26BrN7O14P2 (free acid). Mole weight: 742.32 (free acid). | |
| 8-Bromo-AppNHp | 8-Bromo-AppNHp, a coveted biochemical compound, brimming with potential, is considered an integral tool in the unprecedented scientific endeavors to unravel the mysteries of signal transduction and protein activation pathways. Its significance lies in its extraordinary ability to emulate adenosine triphosphate (ATP), lending an unfiltered glimpse into the functional intricacies of G-proteins and adenylate cyclases. Its presence has revolutionized the world of medicinal research, opening new horizons in the quest to tackle both neurological disorders and cardiovascular diseases. Alternative Names: (8Br-AppNHp, 8Br-AMPPNP); 8-Bromo-adenosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O12P3Br (free acid). Mole weight: 585.09 (free acid). | |
| 8-Bromo-ATP | 8-Bromo-ATP is a potent analog of adenosine triphosphate (ATP), a crucial energy carrier in cells. Widely used in biomedicine, 8-Bromo-ATP exhibits high affinity towards purinergic receptors and is often employed to study their function and signaling pathways. Additionally, this compound serves as a substrate for various enzymatic reactions, enabling researchers to investigate ATP-dependent processes in drug discovery and disease mechanisms. Alternative Names: 8-Bromoadenosine 5'-Triphosphate; (8Br-ATP); 8-Br-ATP; 8-Bromoadenosine 5'-(tetrahydrogen triphosphate); Adenosine, 8-bromo-, 5'-(tetrahydrogen triphosphate); 8-Bromo ATP; 8-Bromoadenosine triphosphate; ((2R,3S,4R,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate. Grades: ≥95% by HPLC. CAS No. 23567-97-7. Molecular formula: C10H15BrN5O13P3. Mole weight: 586.08. | |
| 8-Bromo-dATP | 8-Bromo-dATP is a nucleoside triphosphate analog primarily used in research to investigate DNA damage and repair mechanisms. It can be incorporated into DNA during replication, leading to altered DNA structure and function. Alternative Names: (8Br-dATP); 8-Bromo-2'-deoxyadenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 92410-99-6. Molecular formula: C10H15N5O12P3Br (free acid). Mole weight: 570.08 (free acid). | |
| 8-Bromo-GDP | 8-Bromo-GDP is an exemplary and formidable analogue of guanosine diphosphate (GDP), facilitating the research of GTP-binding proteins and the mechanisms of signaling pathways, protein enmeshment and GTPase activity. Alternative Names: (8Br-GDP); 8-Bromo-guanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N5O11P2Br (free acid). Mole weight: 522.09 (free acid). | |
| 8-Bromo-GMP | 8-Bromo-GMP is a compound used in biomedicine to study the effects of G protein-coupled receptor signaling and phosphodiesterase activity. It has also been studied for its anticancer properties due to its ability to induce cell death in various cancer cell lines. Additionally, 8-Bromo-GMP has been used to mimic the effects of nitric oxide signaling in biological processes. Alternative Names: (8Br-GMP); 8-Bromo-guanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H13N5O8PBr (free acid). Mole weight: 442.11 (free acid). | |
| 8-Bromo-GppNHp | 8-Bromo-GppNHp, a biochemical known for its role in investigating the signaling pathways of G proteins, is gaining notoriety in the field of biomedical research. Primarily, the product is utilized to study G protein-coupled receptors (GPCRs) and their downstream effectors. Beyond that, the research community has found it to be instrumental in studies related to various diseases -- among them cancer, cardiovascular afflictions, and diabetes. As the product continues to prove its worth, it is sure to remain an increasingly important tool for those in the field of biomedical science. Alternative Names: (8Br-GppNHp, 8Br-GMPPNP); 8-Bromo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O13P3Br (free acid). Mole weight: 601.09 (free acid). | |
| 8-Bromo-GTP | 8-Bromo-GTP is a GTP analog that can inhibit GTP-hydrolase. It competitively inhibits GTPase (IC50 = 32 μM) and competes with ATP for the binding center of RNA-polymerase. Alternative Names: (8Br-GTP); 8-Bromo-guanosine-5'-triphosphate; 8-Bromoguanosine 5'-triphosphate; 8-Bromoguanosine triphosphate. Grades: ≥95% by HPLC. CAS No. 23197-98-0. Molecular formula: C10H15BrN5O14P3. Mole weight: 602.08. | |
| 8-Bromoguanine ( 8-Br-Gua ) | 8-Bromoguanine (8-Br-Gua), a potent and versatile compound widely employed in the field of biomedicine, offers immense potential for treating a myriad of ailments, including cancer, when combined with conventional chemotherapeutic agents. Its unprecedented capability to impede the proliferation of malignant cells has been unequivocally established through comprehensive scientific inquiry, positioning it as an auspicious contender for precise and targeted therapeutic interventions. Alternative Names: 2-Amino-8-bromo-6-hydroxypurine; 2-amino-8-bromo-9H-purin-6-ol; 2-amino-8-bromo-1,9-dihydropurin-6-one; 2-amino-8-bromo-3,7-dihydropurin-6-one; 2-Amino-8-bromo-1H-purin-6(7H)-one; 2-Amino-8-bromo-1,7-dihydro-6H-purin-6-one; 2-amino-8-bromopurin-6-ol; NSC 7845. Grades: ≥97% by HPLC. CAS No. 3066-84-0. Molecular formula: C5H4BrN5O. Mole weight: 230.02. | |
| 8-Bromoguanosine | 8-Bromo-guanosine, an extensively studied chemical entity, manifests remarkable potency in the realm of biomedicine owing to its ability to obstruct viral RNA synthesis. Alternative Names: 8-Bromo-guanosine; 8-Bromo-ribo Guanosine; 2-Amino-8-bromo-6-hydroxypurine Riboside; NSC 174257; NSC 79211; 2-amino-8-bromo-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 8-Bromo-D-guanosine; 8-Bromo-9-β-D-ribofuranosylguanine. Grades: ≥98% by HPLC. CAS No. 4016-63-1. Molecular formula: C10H12BrN5O5. Mole weight: 362.14. | |
| 8-Bromoinsine | 8-Bromoinsine is a remarkably powerful and bioactive compound, embodied within its molecular structure lies a potent antiviral potential, holding great application in restraining the proliferation of diverse viral strains. Alternative Names: (2R,3R,4S,5R)-2-(8-bromo-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: 95%. CAS No. 55627-73-1. Molecular formula: C10H11BrN4O5. Mole weight: 347.12. | |
| 8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine | 8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine is a highly prized compound, holding immense value due to its noteworthy potential in studying tumors and viral drugs. This compound can be used to delve into the intricate repercussions of DNA impairment and the subsequent mechanisms involved in its reparation. Grades: ≥ 90%. CAS No. 717876-75-0. Molecular formula: C13H17BrN6O4. Mole weight: 401.21. | |
| 8-Bromo-N6-benzoyl-dA CEP | The 8-Bromo-N6-benzoyl-dA CEP is an indispensable chemical compound that holds immense significance within the biomedicine industry. This remarkable product serves as a linchpin in the process of developing therapeutic drugs targeted towards tackling a myriad of diseases. It exhibits unparalleled utility in the synthesis of nucleotides and nucleic acid analogs, thereby facilitating revolutionary strides in the realm of anti-cancer and anti-viral treatments. Molecular formula: C47H51BrN7O7P. Mole weight: 936.83. | |
| 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine | 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is an exceptionally powerful and discriminatory inhibitor, aiding through precise research within distinct enzymatic mechanisms. F. Alternative Names: 8-BROMO-N6-(DIMETHYLAMINOMETHYLIDENE)-2'-DEOXYADENOSINE; N'-[8-bromo-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-N,N-dimethylmethanimidamide. Grades: ≥ 95%. CAS No. 207906-52-3. Molecular formula: C13H17BrN6O3. Mole weight: 385.21. | |
| 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-β-D-2'-deoxyribofuranosyl]guanine | 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-β-D-2'-deoxyribofuranosyl]guanine is a highly complex compound, standing renowned due to its exceptional antiviral properties. In the pursuit of research of DNA viruses, including herpesviruses, this compound finds its purpose. Through the inhibition of viral DNA replication, it diligently curbs the propagation of viral pathogens. Alternative Names: 9-[(6aR,8R,9aR)-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-8-bromo-1H-purin-6-one; 2-Amino-8-bromo-9-[(6aR,8R,9aR)-2,2,4,4-tetra(propan-2-yl)tetrahydro-2H,4H,6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-3,9-dihydro-6H-purin-6-one; 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-beta-D-2'-deoxyribofuranosyl]guani; DTXSID10747232; 8-Bromo-N9-[3 inverted exclamation mark ,5 inverted exclamation mark -O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-|A-D-2 inverted exclamation mark -deoxyribofuranosyl]guanine. CAS No. 769141-88-0. Molecular formula: C22H38BrN5O5Si2. Mole weight: 588.64. | |
| 8-Br-PET-cGMP | 8-Br-PET-cGMP is a stimulator of isozymes I α and I β of cGMP-dependent protein kinase, which is used as an excellent cyclic nucleotide muscle relaxants. Grades: ≥ 98% by HPLC. CAS No. 144510-04-3. Molecular formula: C18H14BrN5O7P · Na. Mole weight: 546.2. | |
| 8-Br-PET-cGMP Sodium Salt | 8-Br-PET-cGMP Sodium Salt is a pkG cell-permeable activator. Alternative Names: 2-Bromo-3,4-dihydro-6-phenyl-3-(3,5-O-phosphinico-β-D-ribofuranosyl)-9H-imidazo[1,2-a]purin-9-one Sodium Salt. CAS No. 185246-29-1. Molecular formula: C18H14BrN5NaO7P. Mole weight: 546.2. | |
| 8-Br-Xao | 8-Br-Xao, the intriguing research chemical, has gained traction in the biomedical industry for investigating its potential for treating cancer and inflammation. With promising results, it appears to be able to tamper with the activity of crucial enzymes and pathways involved in progressing diseases. Therefore, this compound holds intrigue as a potential drug for treating relevant conditions and is expected to involve further study and development. CAS No. 3001-46-6. Molecular formula: C10H11BrN4O6. Mole weight: 363.1. | |
| 8-BT-cAMP | 8-BT-cAMP is a selective activator of cAMP-dependent protein kinase. Compared to cAMP, it has superior stability and membrane permeability. Alternative Names: 8- Benzylthioadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 50655-17-9. Molecular formula: C17H17N5O6PS · Na. Mole weight: 473.4. | |
| 8-CEA-Ado | 8-CEA-Ado is a reactive precursor for immobilisation. Alternative Names: 8- Carboxyethylaminoadenosine. Grades: ≥ 97 % by HPLC. CAS No. 1161916-63-8. Molecular formula: C13H18N6O6. Mole weight: 364.3. | |
| 8-Chloro-2'-beta-C-methylinosine | 8-Chloro-2'-beta-C-methylinosine, a remarkable compound in the biomedical industry, serves as a powerful antiviral agent. Its efficacy knows no bounds, effectively thwarting the replication of RNA viruses like Zika virus and Hepatitis C. By skillfully targeting viral RNA synthesis and translation, this compound proves its inhibitory potential. Grades: ≥95%. CAS No. 1106012-39-8. Molecular formula: C11H13ClN4O5. Mole weight: 316.70. | |
| 8-Chloro-2'-deoxy-2'-fluoroinosine | 8-Chloro-2'-deoxy-2'-fluoroinosine is a renowned pharmaceutical compound extensively utilized in the biomedical sector, showcasing profound antiviral attributes. Its dominant application pertains to studying the scourge of viral infections induced by the notorious herpes simplex virus, varicella-zoster virus and Epstein-Barr virus. Grades: ≥95%. Molecular formula: C10H10ClFN4O4. Mole weight: 304.66. | |
| 8-Chloro-2'-deoxyadenosine-5'-Triphosphate | 8-Chloro-2'-deoxyadenosine-5'-Triphosphate, an altered nucleoside triphosphate used in DNA synthesis and repair research, exhibits robust inhibition of DNA polymerase and is under investigation as a cancer treatment. In sequencing technology, 8-Chloro-2'-deoxyadenosine-5'-Triphosphate serves as a valuable probe. Alternative Names: 8-Chloro-dATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N5O12P3Cl. Mole weight: 525.60. | |
| 8-Chloro-2'-O-methylinosine | 8-Chloro-2'-O-methylinosine, an essential compound for the advancement of antiviral medications, plays a pivotal role in combating diverse viral infections including hepatitis C and respiratory syncytial virus (RSV). By impeding viral replication and leveraging its robust antiviral capabilities, this compound effectively aids in the management of these ailments. Grades: ≥95%. Molecular formula: C11H13ClN4O5. Mole weight: 316.70. | |
| 8-Chloroadenosine | 8-Chloroadenosine is an analog of adenosine. It is metabolized in vivo to 8-Chloro-ATP. It depletes ATP and inhibits tumor growth in hematological malignancies. It also inhibits tumor growth in lung and breast cancer cell lines. It incorporates into RNA during transcription and inhibits RNA synthesis. It mitotics catastrophe and induces G2/M cell cycle arrest in A549 and H1299 cells. It is a useful research chemical and has cytotoxicity effects. Alternative Names: 6-Amino-8-chloropurine riboside; 8-Cl-Ado; 8-Chloro-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-adenosine. Grades: ≥98% by HPLC. CAS No. 34408-14-5. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. | |
| 8-Chloroadenosine 3',5'-Cyclic Monophosphate | 8-Chloroadenosine 3',5'-Cyclic Monophosphate is a cAMP analog with high selectivity for PKA I. Used in anti-cancer treatments. Uses: Antineoplastic agents. Alternative Names: 8-Chloro-cAMP; 8-Chloro-cyclic AMP; 8-Chloroadenosine 3',5'-Cyclic Monophosphate; 8-Chloroadenosine 3',5'-Cyclic Phosphate; Adenazole; NSC 284751; NSC 614491; Tocladesine. Grades: 95%. CAS No. 41941-56-4. Molecular formula: C10H11ClN5O6P. Mole weight: 363.65. | |
| 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate | 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate is a key compound used in biomedical research. It acts as an adenosine receptor agonist, exhibiting therapeutic potential in the treatment of various diseases including cancer, inflammation, and neurodegenerative disorders. Its unique properties make it an essential tool for studying nucleotide signaling pathways and developing targeted therapies to combat these conditions. Molecular formula: C10H11ClN5O6P·2H2O. Mole weight: 399.69. | |
| 8-Chloroguanosine | Burstiness and perplexity encapsulate two vital aspects of effective content writing. Introducing 8-Chloroguanosine, an invaluable chemical compound extensively utilized in the biomedical sector, aimed at investigating the intricate repercussions of oxidative stress-induced DNA impairment. Its eminent significance persists in the profound comprehension of DNA repair mechanisms and replication processes, primarily applicable in pioneering disease therapies, including cancer. Alternative Names: 8-Cl-Guo; 2-Amino-8-chloro-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 8-chloro-; 8-Chloro-D-guanosine. Grades: ≥98% by HPLC. CAS No. 2104-68-9. Molecular formula: C10H12ClN6O6. Mole weight: 317.69. | |
| 8-Chloroinosine | A major metabolite of 8-Chloroadenosine. Alternative Names: 8-Chloro-inosine; 8-Cl-I; (2R,3R,4S,5R)-2-(8-Chloro-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-inosine; 9H-Purin-6-ol, 8-chloro-9-β-D-ribofuranosyl-. Grades: ≥95%. CAS No. 116285-77-9. Molecular formula: C10H11ClN4O5. Mole weight: 302.67. | |
| 8-Cl-2'-FDA-AEC-cAMP | 8-Cl-2'-FDA-AEC-cAMP is an extraordinary cyclic AMP analogue, emerging as an exquisite research tool within the biomedical sphere. Its versatile nature leads to unravelling the enigmatic cAMP-dependent signalling pathways and illuminating the intricate world of signal transduction. Alternative Names: 8- Chloro- 2'- O- (fluoresceindiacetate- (2- aminoethylcarbamoyl))adenosine- 3', 5'- cyclic monophosphate. | |
| 8-Cl-5'-AMP | 8-Cl-5'-AMP is a potential metabolite of 8-chloroadenosine-3',5'-cyclic monophosphate. Alternative Names: 8- Chloroadenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 37676-40-7. Molecular formula: C10H13ClN5O7P (free acid). Mole weight: 381.7 (free acid). | |
| 8-Cl-Ado | 8-Cl-Ado is a cytotoxic metabolite of 8-chloro cyclic AMP. Alternative Names: 8- Chloroadenosine. Grades: ≥ 98% by HPLC. CAS No. 34408-14-6. Molecular formula: C10H12ClN6O4. Mole weight: 301.7. | |
| 8-Cl-ADP | 8-Cl-ADP is a metabolite of 8-Cl-cAMP and 8-Cl-adenosine and a precursor of 8-modified ADP derivatives. Alternative Names: 8- Chloroadenosine- 5'- O- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 185341-69-9. Molecular formula: C10H14ClN5O10P2 (free acid). Mole weight: 461.7 (free acid). | |
| 8-Cl-ATP | 8-Cl-ATP is a corresponding triphosphate form for research on 8-chloro cAMP and 8-Cl-adenosine. Alternative Names: 8- Chloroadenosine- 5'- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 185341-71-3. Molecular formula: C10H15ClN5O13P3 (free acid). Mole weight: 541.6 (free acid). | |
| 8-Cl-cAMP | 8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effect of growth and differentiation in cultured cancer cell lines. Alternative Names: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 124705-03-9. Molecular formula: C10H10ClN5O6P · Na. Mole weight: 385.6. | |
| 8-Cl-cAMP-AM | 8-Cl-cAMP-AM is a precursor of 8-Cl-cAMP, the PKA activator. The polar active analogue is released after the metabolism of 8-Cl-cAMP-AM by esterases. Alternative Names: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C13H15ClN5O8P. Mole weight: 435.7. | |
| 8-Cl-c-diAMP | 8-Cl-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which is used for binding studies and precursor for further modifications with spacers or labels. Alternative Names: 8- Chloro- cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23ClN10O12P2 (free acid). Mole weight: 692.9 (free acid). | |
| 8-Cl-dAdo | 8-Cl-dAdo is a formidable and discriminating inhibitory compound, enthralling the enzyme ribonucleotide reductase. Alternative Names: 8- Chloro- 2'- deoxyadenosine. Grades: ≥ 96% by HPLC. CAS No. 86662-66-6. Molecular formula: C10H12ClN6O3. Mole weight: 286.7. | |
| 8-Cl-dGuo | 8-Cl-dGuo, an anti-RNA virus crusader, is a nucleoside of robust antiviral power. Employed in treating life-threatening hepatitis C and coronavirus, it exercises the incredible ability of obstructing viral RNA replication. With a track record of reining in multiple viral strains, 8-Cl-dGuo, thanks to its singular structural features, is a forerunner in directing medicines to infected cells, shielding healthy tissues from toxicity. Alternative Names: 8- Chloro- 2'- deoxyguanosine. Grades: ≥ 96% by HPLC. CAS No. 437716-62-3. Molecular formula: C10H12ClN6O4. Mole weight: 301.7. | |
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