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Chlormezanone
Chlormezanone, a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. Uses: Anti-anxiety agents; muscle relaxants, central. Synonyms: ASP1517; ASP 1517; ASP-1517. Grade: >98%. CAS No. 80-77-3. Molecular formula: C11H12ClNO3S. Mole weight: 273.74.
Chlormidazole hydrochloride
Chlormidazole hydrochloride, an antifungal agent, has inhibitory activity against a variety of fungi and some Gram-positive cocci. It is used for fungal and bacterial infections of the nail and skin, including interdigital and periungual mycoses. Synonyms: Clomidazole hydrochloride; 1-[(4-Chlorophenyl)methyl]-2-methyl-1H-benzimidazole Hydrochloride; 1-[(4-Chlorophenyl)methyl]-2-methyl-1H-benzimidazole Monohydrochloride; 1-(p-Chlorobenzyl)-2-methyl-benzimidazole Hydrochloride; 1-(4-Chlorobenzyl)-2-methyl-1H-benzimidazole hydrochloride (1:1). Grade: 95%. CAS No. 74298-63-8. Molecular formula: C15H13ClN2.HCl. Mole weight: 293.19.
Chlorobenzhydryl Piperazine is an impurity of Levocetirizine, an antihistamine used to relieve allergy symptoms. Synonyms: (-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine; (R)-1-(p-Chlorobenzhydryl)piperazine. Grade: > 95%. CAS No. 300543-56-0. Molecular formula: C17H19ClN2. Mole weight: 286.80.
Chlorobromo Isocyanuric Acid
An impurity of Gimeracil which is a pyridine derivative with antitumor activity. Synonyms: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-bromo-3-chloro-. CAS No. 89325-49-5. Molecular formula: C3HBrClN3O3. Mole weight: 242.42.
Chloromethyl Isopropyl Carbonate
Chloromethyl Isopropyl Carbonate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: CMIC; Carbonic acid, chloromethyl 1-methylethyl ester; Chloromethyl 1-methylethyl carbonate; [(Isopropyloxycarbonyl)oxy]methyl chloride; Isopropoxycarbonyloxymethyl chloride; Isopropyl chloromethyl carbonate. Grade: 95%. CAS No. 35180-01-9. Molecular formula: C5H9ClO3. Mole weight: 152.58.
Chloromethylisothiazolinone
5-Chloro-2-methyl-4-Isothiazolin-3-one is an isothiazolinone-derived biocide used for controlling microbial growth in water-containing solutions. Synonyms: 5-Chloro-2-methylisothiazol-3-one; 5-Chloro-2-methyl-Isothiazolin-3-one; 5-Chloro-2-methyl-3(2H)-isothiazolone; 5-Chloro-2-Methyl-4-Isothiazolin-3-One; 5-chloro-2-methyl-1,2-thiazol-3(2H)-one; 5-Chloride-2-Methyl-4-Isothiazoline-3-Ketone; 1-(4-CHLOROPHENYL)-3-(3,4-DICHLOROPHENYL)UREA. Grade: 0.99. CAS No. 26172-55-4. Molecular formula: C4H4ClNOS. Mole weight: 186.06.
Chloromethyl (S,R)-Palonosetron Chloride
Chloromethyl (S,R)-Palonosetron Chloride is a by-product of (S,R)-Palonosetron Hydrochloride. Molecular formula: C20H26Cl2N2O. Mole weight: 381.34.
Chlorophenol red b-D-galactopyranoside
Chlorophenol red b-D-galactopyranoside is a substrate commonly used in biochemical assays to detect the presence and activity of β-galactosidase. Upon cleavage by β-galactosidase, the substrate produces a yellow color that can be quantified to measure enzyme activity. This product is useful in detecting lactose utilization and the presence of coliforms, aiding in diagnosis of gastrointestinal diseases. Synonyms: CPRG; 2-Chloro-4-[3-(3-chloro-4-hydroxyphenyl)-1,1-dioxido-3H-2,1-benzoxathiol-3-yl]phenyl β-D-galactopyranoside; β-D-Galactopyranoside, 2-chloro-4-[3-(3-chloro-4-hydroxyphenyl)-3H-2,1-benzoxathiol-3-yl]phenyl, S,S-dioxide; Chlorophenol red galactopyranoside. CAS No. 99792-79-7. Molecular formula: C25H22Cl2O10S. Mole weight: 585.41.
Chlorophenol red-b-D-galactopyranoside sodium salt
Chlorophenol red-b-D-galactopyranoside sodium salt is a biochemical reagent used in the biomedical industry. This product is commonly employed in various assays and experiments to detect the presence of β-galactosidase activity. It acts as a chromogenic substrate, turning red upon enzymatic hydrolysis by β-galactosidase. Synonyms: CPRG; β-D-Galactopyranoside, 2-chloro-4-[3-(3-chloro-4-hydroxyphenyl)-1,1-dioxido-3H-2,1-benzoxathiol-3-yl]phenyl, sodium salt (1:1); β-D-Galactopyranoside, 2-chloro-4-[3-(3-chloro-4-hydroxyphenyl)-1,1-dioxido-3H-2,1-benzoxathiol-3-yl]phenyl, monosodium salt; β-D-Galactopyranoside, 2-chloro-4-[3-(3-chloro-4-hydroxyphenyl)-3H-2,1-benzoxathiol-3-yl]phenyl, S,S-dioxide, monosodium salt; Chlorophenol Red β-D-galactopyranoside monosodium salt. CAS No. 99792-50-4. Molecular formula: C25H21Cl2NaO10S. Mole weight: 607.39.
Chlorophenol red β-D-cellotrioside
Chlorophenol red β-D-cellotrioside. Synonyms: 2-Chloro-4-[3-(3-chloro-4-hydroxyphenyl)-1,1-dioxido-3H-2,1-benzoxathiol-3-yl]phenyl O-β-D-glucopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranoside. CAS No. 2892641-86-8. Molecular formula: C37H42Cl2O20S. Mole weight: 909.68.
Chloropretadalafil-13C2-d2
One of the labelled impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatment of erectile dysfunction. Grade: 95% by HPLC; 98% atom D. Molecular formula: C20[13C]2H17ClN2O5D2. Mole weight: 430.85.
Chloropyramine hydrochloride
Chloropyramine hydrochloride is a histamine receptor H1 antagonist. It is known for its ability to inhibit the biochemical functions of VEGFR-3 and FAK, making it a potential agent in cancer research and treatment. It is primarily used as an antihistamine in pharmaceutical applications. Synonyms: 1,2-Ethanediamine, N1-[(4-chlorophenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-, hydrochloride (1:x); N-Dimethylaminoethyl-N-p-chlorobenzyl-α-aminopyridine hydrochloride; N-[(4-Chlorophenyl)methyl]-N,N-dimethyl N-2-pyridinyl-1,2-ethanediamine hydrochloride; 2-[(p-Chlorobenzyl)(2-dimethylaminoethyl)amino]pyridine hydrochloride; Avapena hydrochloride; Chlorneoantergan hydrochloride; Chloropyribenzamine hydrochloride; Chlorpyramine hydrochloride; Halopyramine hydrochloride. Grade: 95%. CAS No. 10458-04-5. Molecular formula: C16H20ClN3.xHCl. Mole weight: 289.81 (free base).
Chloropyramine impurity
An impurity of Chloropyramine which is histamine H1-receptor antagonist. Synonyms: p-Chlorobenzylaminopyridine. Grade: > 95%. CAS No. 22881-33-0. Molecular formula: C12H11ClN2. Mole weight: 218.69.
Chloropyramine impurity HCl (salt)
An impurity of Chloropyramine which is a competitive reversible H1-receptor antagonist with anticholinergic properties. Synonyms: (p-Chlorobenzyl Ether) HCl. Grade: > 95%. CAS No. 91428-63-6. Molecular formula: C11H16ClNO. Mole weight: 250.16.
Chloropyramine monohydrochloride
Chloropyramine monohydrochloride is a histamine receptor H1 antagonist. It is known for its ability to inhibit the biochemical functions of VEGFR-3 and FAK, making it a potential agent in cancer research and treatment. It is primarily used as an antihistamine in pharmaceutical applications. Synonyms: Halopyramine Hydrochloride; N-(β-Dimethylaminoethyl)-N-(p-chlorobenzyl)-α-aminopyridine Hydrochloride; NSC 409949; Sinopen Hydrochloride; Suprastin Hydrochloride; Alergosan; Allergan S Hydrochloride; Chlorpyramine Hydrochloride; Chloropyribenzamine Hydrochloride; 2-[(p-Chlorobenzyl)[2-(dimethylamino)ethyl]amino]-pyridine Monohydrochloride; N-[(4-Chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine Monohydrochloride; N1-[(4-Chlorophenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-1,2-ethanediamine Hydrochloride; Chloropyramine hydrochloride. CAS No. 6170-42-9. Molecular formula: C16H20ClN3.HCl. Mole weight: 326.26.
Chloropyrazine Carboxamide
An derivative of Pyrazine.Pyrazine is a heterocyclic aromatic organic compound. Grade: > 95%. CAS No. 76599-74-1. Molecular formula: C6H7ClN6O2. Mole weight: 230.61.
Chloroquine
An antimalarial agent. Synonyms: Aralen; Chlorochin; Chloraquine. Grade: 99.98%. CAS No. 54-05-7. Molecular formula: C18H26ClN3. Mole weight: 319.87.
Chloroquine Dihydrochloride
Chloroquine diphosphateis an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an Autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM). Synonyms: 1,?4-Pentanediamine, N4-(7-chloro-4-quinolinyl)?-N1,?N1-diethyl-, hydrochloride. Grade: > 95%. CAS No. 3545-67-3. Molecular formula: C18H28Cl3N3. Mole weight: 392.79.
Chloroquine phosphate
Chloroquine phosphate is an antimalarial drug and weak intercalating agent. It inhibits TLR signalling in plasmacytoid dendritic cells (pDCs). It has been used in emergency of COVID-19. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt; Aralen diphosphate; C2301; C 2301; C-2301; Chloroquine Diphosphate. Grade: ≥98% (HPLC). CAS No. 50-63-5. Molecular formula: C18H32ClN3O8P2. Mole weight: 515.86.
Chloro Sofosbuvir
Chloro Sofosbuvir is an impurity of Sofosbuvir; a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: N-[[P(S),2'R]-2'-Chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester. Grade: ≥98% (HPLC). CAS No. 1496552-51-2. Molecular formula: C22H29ClN3O9P. Mole weight: 545.91.
Chlorothalonil
Chlorothalonil, a polychlorinated aromatic broad-spectrum fungicide, can effectively protect plants from fungal diseases caused mainly by Phytophthora infestans and Alternaria solani. It is used to control fungal foliar diseases on vegetables and crops. Uses: Fungicides, industrial. Synonyms: Dicyanotetrachlorobenzene; 2,4,5,6-Tetrachloro-1,3-dicyanobenzene; Tetrachloroisophthalonitrile; Nopcocide; Tetrachlorobenzene-1,3-dicarbonitrile; Daconil; Bravo; m-Tcpn; 1,3-Dicyanotetrachlorobenzene; 2,4,5,6-Tetrachloroisophthalonitrile. Grade: ≥95%. CAS No. 1897-45-6. Molecular formula: C8Cl4N2. Mole weight: 265.91.
Chlorothiazide
Chlorothiazide is a thiazide diuretic used for the treatment of edema caused by various medical problems. Chlorothiazide is also an impurity of Hydrochlorothiazide. Synonyms: Diuril. CAS No. 58-94-6. Molecular formula: C7H6ClN3O4S2. Mole weight: 295.72.
Chlorotrianisene
Chlorotrianisene is a powerful synthetic, non-steroidal estrogenic compound which is metabolized by liver microsomal enzymes primarily to the mono-O-demethylated derivative. It binds to the estrogen receptor on various estrogen receptor bearing cells. It was used for the treatment of menopause, deficiencies in ovary function, and prostate cancer. It belongs triphenylethylene group. It was derived from estrobin (DBE) and is a relatively weak estrogen. It is a selective estrogen receptor modulator (SERM), with predominantly estrogenic but also antiestrogenic effects, and was arguably the first SERM to ever be introduced. It has been listed. Uses: Chlorotrianisene was used for the treatment of menopause, deficiencies in ovary function, and prostate cancer. Synonyms: 1,1',1''-(1-Chloro-1-ethenyl-2-ylidene)-tris(4-methoxybenzene); 1-[2-Chloro-1,2-bis(4-methoxyphenyl)vinyl]-4-methoxybenzene; Chlortrianisestrol; Chlortrianizen; Khlortrianizen; Hormonisene; Anisene; Metace; Rianil; Tace; 1-[1-Chloro-2,2-bis(4-methoxyphenyl)ethenyl]; Chlorotrianisene; Chlortrianisestrol; Chlortrianizen; Chlorotrianisine; Chlorestrolo; Chlorotrianizen; Khlortrianizen; Clorestrolo; Clorotrisin; Hormonisene; Anisene; Metace; Rianil; Tace. Grade: 95%. CAS No. 569-57-3. Molecular formula: C23H21ClO3. Mole weight: 380.87.
Chlorphenamine EP Impurity C
An impurity of Chlorpheniramine, which inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 μM. Synonyms: N-Desmethylchlorpheniramine; monodesmethylchlorpheniramine; N-Methyl-3-(4-chlorophenyl)-3-(2-pyridyl)propan-1-amine; γ-(4-Chlorophenyl)-N-methyl-2-pyridinepropanamine. Grade: 95%. CAS No. 20619-12-9. Molecular formula: C15H17ClN2. Mole weight: 260.76.
Chlorphenamine Impurity B (2,2'-Dipyridylamine)
A metal-complexing agent; an effective iron chelating agent to help protect against UVB radiation. An impurity of Chlorpheniramine Maleate. Synonyms: 2,2'-Iminodipyridine; 2,2'-Bipyridylamine; 2,2'-Iminodipyridine; 2-(2-Pyridylamino)pyridine; Bis(2-pyridyl)amine; Bis(o-pyridyl)amine; Bis(pyridin-2-yl)amine; Di-2-pyridylamine; Di-α-pyridylamine; Dipyridin-2-ylamine; N-(2-Pyridinyl)-2-pyridinamine; NSC 7. Grade: > 95%. CAS No. 1202-34-2. Molecular formula: C10H9N3. Mole weight: 171.2.
Chlorphenamine Impurity C Maleate
A metabolite of Chlorpheniramine, an antihistamine that works by blocking the action of histamine. Synonyms: N-Desmethyl-Chlorpheniramine; 2-[p-Chloro-α-[2-(methylamino)ethyl]benzyl]pyridine Maleate. Grade: > 95%. CAS No. 22630-25-7. Molecular formula: C15H17ClN2.C4H4O4. Mole weight: 376.8.
Chlorphenamine Impurity D
An impurity of Chlorpheniramine which is an antihistamine and works by blocking the action of histamine. Synonyms: Chlorpheniramine Nitrile. Grade: > 95%. CAS No. 65676-21-3. Molecular formula: C17H18ClN3. Mole weight: 299.81.
Chlorphenamine maleate EP Impurity A
an impurity of Chlorphenamine. Synonyms: Benzeneacetonitrile, 4-?chloro-?α,?α-?bis[2-?(dimethylamino)?ethyl]?-. Grade: > 95%. CAS No. 1246816-57-8. Molecular formula: C16H24ClN3. Mole weight: 293.83.
Chlorpheniramine N-Oxide
Chlorpheniramine N-Oxide is the major metabolite of Chlorpheniramine. Chlorpheniramine inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 μM. Synonyms: 2-Pyridinepropanamine,γ-(4-chlorophenyl)-N,N-dimethyl-N-Oxide. Grade: > 95%. CAS No. 120244-82-8. Molecular formula: C16H19ClN2O. Mole weight: 290.79.
Chlorpheniramine N-Oxide HCl
An impurity of Chlorpheniramine which inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner and is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. Grade: > 95%. Molecular formula: C16H19ClN2O.HCl. Mole weight: 327.26.
Chlorphenoxamine
Chlorphenoxamine is an analog of diphenhydramine. It has antimuscarinic and antihistaminic properties. It has been used as an antipruritic and antiparkinsonian agent. Uses: Chlorphenoxamine has been used as an antipruritic and antiparkinsonian agent. Synonyms: 2-(1-(p-Chlorophenyl)-1-phenylethoxy)-N,N-dimethylethylamine; 2-[1-(4-Chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine; beta-Dimethylamino-aethyl-(p-chlor-alpha-methylbenzhydryl)-aether; Ethylamine, 2-[1-(p-chlorophenyl)-1-phenylethoxy]-N,N-dimethyl-; p-Chlor-alpha-methyl-diphenhydramin; N-(2-(1-p-chlorophenyl-1-phenylethoxy)ethyl)dimethylamine; 1-(4-Chlorophenyl)-1-[2-(dimethylamino)ethoxy]-1-phenylethane; Contristamine; Systral. Grade: >98%. CAS No. 77-38-3. Molecular formula: C18H22ClNO. Mole weight: 303.84.
Chlorpromazine EP Impurity B
Chlorpromazine EP Impurity B is an impurity of chlorpromazine, an antipsychotic used to treat psychotic disorders such as schizophrenia. Synonyms: 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine; Chlorpromazine Impurity B. CAS No. 19077-20-4. Molecular formula: C21H28ClN3S. Mole weight: 389.986.
Chlorpromazine EP Impurity D
An impurity of Chlorpromazine. Chlorpromazine is an antipsychotic medication. It can be used to treat psychotic disorders such as schizophrenia. Uses: A metabolite of chlorpromazine (c424750). Synonyms: 2-Chloro-N-methyl-10H-phenothiazine-10-propanamine Hydrochloride; 2-Chloro-10-(3-methylaminopropyl)phenothiazine Hydrochloride; Desmethylchlorpromazine Hydrochloride; Mono-N-demethylchloropromazine Hydrochloride. CAS No. 3953-65-9. Molecular formula: C16H18Cl2N2S. Mole weight: 341.30.
Chlorpromazine N-Oxide
An impurity of Chlorpromazine. Chlorpromazine is an antipsychotic medication. It can be used to treat psychotic disorders such as schizophrenia. Synonyms: Chlorpromazine-N-oxide; 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, N-oxide; 2-chloro-10-(3'-dimethyloxidoaminopropyl)phenothiazine; [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine oxide; Chlorpromazine oxide; Ba 2836; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine N-oxide; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine oxide. Grade: > 95%. CAS No. 1672-76-0. Molecular formula: C17H19ClN2OS. Mole weight: 334.87.
Chlorpromazine-N-S-dioxide
An impurity of Chlorpromazine. Chlorpromazine is an antipsychotic medication. It can be used to treat psychotic disorders such as schizophrenia. Synonyms: 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine N,5-dioxide; Chloropromazine N-oxide sulfoxide. CAS No. 10404-90-7. Molecular formula: C17H19ClN2O2S. Mole weight: 350.86.
Chlorpromazine Sulfone Hydrochloride
An impurity of Chlorpromazine. Chlorpromazine is an antipsychotic medication. It can be used to treat psychotic disorders such as schizophrenia. Synonyms: 2-Chloro-10-(3-(dimethylamino)propyl)-10H-phenothiazine 5,5-dioxide hydrochloride. CAS No. 18683-73-3. Molecular formula: C17H20Cl2N2O2S. Mole weight: 387.32.
Chlorpromazine Sulfoxide
A devirative of Chlorpromazine. Chlorpromazine is an antipsychotic medication. It can be used to treat psychotic disorders such as schizophrenia. Synonyms: 2-Chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine 5-Oxide; 2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine 5-Oxide; NSC 17470; Opromazine. Grade: > 95%. CAS No. 969-99-3. Molecular formula: C17H19ClN2OS. Mole weight: 334.87.
Chlorpropamide
Chlorpropamide is a drug in the sulfonylurea class used to treat type 2 diabetes mellitus. It is a long-acting 1st generation sulfonylurea. Grade: >98%. CAS No. 94-20-2. Molecular formula: C10H13ClN2O3S. Mole weight: 276.74.
Chlorprothixene
Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively. Uses: Antipsychotic agents; dopamine antagonists. Grade: >98%. CAS No. 113-59-7. Molecular formula: C18H18ClNS. Mole weight: 315.86.
Chlorprothixene hydrochloride
Chlorprothixene hydrochloride is the hydrochloride salt form of chlorprothixene, a typical thioxanthine antipsychotic that functions by antagonizing dopamine D2 receptors. It can block a subset of GABAA receptors in rat cortex that is also blocked by clozapine. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. It has also been shown to be effective against P. falciparum growth with an EC50 value of 1.7 μM. Synonyms: cis-Chlorprothixene; NSC 169899; Minithixen hydrochloride; Truxal hydrochloride; NSC 56379; NSC 78193; (3Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine; hydrochloride. Grade: ≥98%. CAS No. 6469-93-8. Molecular formula: C18H18ClNS·HCl. Mole weight: 352.3.
Chlorpyrifos oxon
Chlorpyrifos-oxon, a metabolite of Chlorpyrifos in human, is a potent phosphorylating agent that potently inhibits AChE. Synonyms: Phosphoric Acid Diethyl 3,5,6-Trichloro-2-pyridinyl Ester; 6-Trichloro-2-pyridyl Diethyl Phosphate; Chlorpyrifos-ethyl Oxon; Chlorpyriphoxon; Diethyl 3,5,6-Trichloro-2-pyridyl Phosphate; Dursban Oxygen Analog; Dursbanoxon; Fospirate-ethyl; O,O-Diethyl O-3,5,6-Trichloro-2-pyridyl Phosphate; O-(3,5,6-Trichloro-2-pyridinyl) O,O-Diethyl Phosphate. CAS No. 5598-15-2. Molecular formula: C9H11Cl3NO4P. Mole weight: 334.52.
Chlorquinaldol
Chlorquinaldol is an antimicrobial agent. Uses: Anti-infective agents. Synonyms: 5,7-Dichloro-8-hydroxy-2-methylquinoline. Grade: > 98 %. CAS No. 72-80-0. Molecular formula: C10H7Cl2NO. Mole weight: 228.07.
Chlortalidone EP Impurity A
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: 2-(4-Chloro-3-sulfamoylbenzoyl)benzoic acid; Chlortalidone Impurity A. Grade: ≥95%. CAS No. 345930-32-7. Molecular formula: C14H9ClO6S. Mole weight: 340.74.
Chlortalidone EP Impurity C
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: Chlorthalidone Acid Ethyl Ester; 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid Ethyl Ester; o-(4-Chloro-3-sulfamoylbenzoyl)-benzoic Acid Ethyl Ester. Grade: > 95%. CAS No. 92874-73-2. Molecular formula: C16H14ClNO5S. Mole weight: 367.81.
Chlortalidone EP Impurity D
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: O-Ethyl Chlorthalidone; 2-Chloro-5-(1-ethoxy-3-oxoisoindolin-1-yl)benzenesulfonamide. Grade: > 95%. CAS No. 1369995-36-7. Molecular formula: C16H15ClN2O4S. Mole weight: 366.83.
Chlortalidone EP Impurity E
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: 3-Dehydroxy Chlorthalidone; Chlorthalidone Deshydroxy Impurity; 3-(3-Sulfamyl-4-chlorophenyl)phthalimidine; 2-Chloro-5-(2,3-dihydro-3-oxo-1H-isoindol-1-yl)-benzenesulfonamide. Grade: > 95%. CAS No. 82875-49-8. Molecular formula: C14H11ClN2O3S. Mole weight: 322.77.
Chlortalidone EP Impurity F
Dimer Conjugate of Chlorthalidone, a diuretic and antihypertensive agent. Synonyms: Chlorthalidone Dimer; bis[2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulphonyl]amine; 2-Chloro-N-(2-chloro-5-(1-hydroxy-3-oxoisoindolin-1-yl)phenylsulfonyl)-5-(1-hydroxy-3-oxoisoindolin-1-yl)benzenesulfonamide. Grade: > 95%. CAS No. 1796929-84-4. Molecular formula: C28H19Cl2N3O8S2. Mole weight: 660.51.
Chlortalidone EP Impurity G
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: Chloro Chlorthalidone; Chlorthalidone Dichloro Impurity; (3RS)-3-(3,4-Dichlorophenyl)-3hydroxy-2,3-dihydro-1H-isoindol-1-one. Grade: > 95%. CAS No. 16289-13-7. Molecular formula: C14H9Cl2NO2. Mole weight: 294.14.
Chlortalidone EP Impurity H
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: O-Isopropyl Chlorthalidone; 2-Chloro-5-[(1RS)-1-(1-mehtylethoxy)-3-oxo-2,3-dihydro-1H-isoindol-1-yl]benzenesulfonamide; 2-Chloro-5-(1-isopropoxy-3-oxoisoindolin-1-yl)benzenesulfonamide; 2-Chloro-5-[2,3-dihydro-1-(1-methylethoxy)-3-oxo-1H-isoindol-1-yl]benzenesulfonamide. Grade: ≥95%. CAS No. 2200280-98-2. Molecular formula: C17H17ClN2O4S. Mole weight: 380.85.
Chlortalidone EP Impurity I
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: Benzoic acid, 2-[3-(aminosulfonyl)-4-chlorobenzoyl]-, 1-methylethyl ester; 1-Methylethyl 2-[3-(aminosulfonyl)-4-chlorobenzoyl]benzoate; Chlortalidone impurity I; Isopropyl 2-(4-chloro-3-sulfamoylbenzoyl)benzoate; 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid Isopropyl Ester; O-(4-Chloro-3-sulfamoylbenzoyl)-benzoic Acid Isopropyl Ester; Chlorthalidone Acid Isopropyl Ester. Grade: ≥95%. CAS No. 2514668-27-8. Molecular formula: C17H16ClNO5S. Mole weight: 381.83.
chlortetracycline hydrochloride (1:x)
Chlortetracycline HCl is the first identified tetracycline antibiotic. Uses: Anti-bacterial agents. Synonyms: Chlortetracycline HCl; (4aS,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide hydrochloride. Grade: >98%. CAS No. 3671-8-7. Molecular formula: C22H23ClN2O8.xHCl. Mole weight: 478.886 (free base).
Chlorthal-dimethyl
Chlorthal-dimethyl, also called as Dacthal, it is metabolized in animals to monomethyl ester and chlorthal which are eliminated in urine and used as a pesticide intermediate. Synonyms: dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Dacthal DCPA dimethyl 2,3,5,6-tetrachloro-terephthalate dimethyl 2,3,5,6-tetrachloroterephthalate. CAS No. 1861-32-1. Molecular formula: C10H6Cl4O4. Mole weight: 331.96.
Chlorthalidone Methyl Ether
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: O-Methyl Chlorthalidone; 2-chloro-5-(1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide. CAS No. 96512-76-4. Molecular formula: C15H13ClN2O4S. Mole weight: 352.79.
Chlorthalidone USP Related Compound A
An impurity of Chlorthalidone. Chlorthalidone is a long-acting thiazide-like diuretic used primarily for the treatment of hypertension and edema. Synonyms: Chlorthalidone Related Compound A; USP Chlorthalidone Related Compound A; 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]benzoic acid; O-(4-Chloro-3-sulfamoylbenzoyl)-benzoic acid; 4'-Chloro-3'-sulfamoyl-2-benzophenone-2-carboxylic acid. Grade: ≥95%. CAS No. 5270-74-6. Molecular formula: C14H10ClNO5S. Mole weight: 339.76.
Chlorzoxazone
Chlorzoxazone is a muscle-relaxing drug, and a probe for human liver cytochrome P-450IIE1. Uses: Muscle relaxants, central. Synonyms: Chlorzoxazone; Paraflex; 5-Chloro-2-benzoxazolone; Chlorzoxazon; Myoflexin; McNeil Brand of Chlorzoxazone; Ortho Brand of Chlorzoxazone; Paraflex; Parafon; Parafon; Forte; DSC. Grade: >98%. CAS No. 95-25-0. Molecular formula: C7H4ClNO2. Mole weight: 169.57.
Chlorzoxazone-13C,15N,D2
An isotope labelled of Chlorzoxazone. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. Grade: 95% by HPLC; 98% atom D;98% atom 13C;98% atom 15N. Molecular formula: C6[13C]H2D2Cl[15N]O2. Mole weight: 173.56.
CHM 1
CHM 1 is an apoptosis inducer with potent antitumor activity in human hepatocellular carcinoma. It inhibits tubulin polymerization in vitro and in vivo, and results in cell cycle arrest at G2/M phase by activating Cdc2 kinase activity. CHM 1 also exhibits vascular targeting activity via upregulation of p53 and induction of death receptor (DR5)-mediated apoptosis in HUVEC cells. Uses: Antitumor agent. Synonyms: CHM-1; CHM 1; CHM1; NSC 656158; NSC-656158; NSC656158; 6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one. Grade: ≥99% by HPLC. CAS No. 154554-41-3. Molecular formula: C16H10FNO3. Mole weight: 283.25.
CHMFL-ABL-039
CHMFL-ABL-039 is a type II native inhibitor of ABL kinase and drug-resistant V299L mutant BCR-ABL with the IC50s of 7.9 and 27.9 nM, respectively. It is used in the study of chronic myeloid leukemia. Synonyms: N-{4-[2-({6-[(Cyclopropylcarbonyl)amino]-3-pyridinyl}amino)-2-oxoethyl]phenyl}-4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzamide; Benzeneacetamide, N-[6-[(cyclopropylcarbonyl)amino]-3-pyridinyl]-4-[[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzoyl]amino]-. CAS No. 2304344-56-5. Molecular formula: C31H33F3N6O3. Mole weight: 594.63.
CHMFL-ABL-053
CHMFL-ABL-053 is a potent and orally available inhibitor of BCR-ABL (IC50 = 70 nM) without inhibitory activity against c-KIT kinase that is a common target of BCR-ABL inhibitors currently used. A pharmacokinetic study revealed that it had 4.3h of half-life and 24% bioavailability in rats. It is developed for the treatment of chronic myeloid leukemia (CML). Uses: The treatment of chronic myeloid leukemia (cml). Synonyms: CHMFL-ABL-053; CHMFL-ABL053; CHMFL-ABL 053. 2 - ((3-Amino-4-methylphenyl)amino) - N - (2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide. CAS No. 1808287-83-3. Molecular formula: C28H26F3N7O2. Mole weight: 549.56.
CHMFL-ABL-121
CHMFL-ABL-121 is a highly potent inhibitor of type II ABL kinase with IC50s of 2 nM and 0.2 nM against purified inactive ABL wt and T315I kinase protein, respectively. Synonyms: Propanamide, N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-; N-{4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-3-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)propanamide. Grade: ≥97%. CAS No. 2270879-07-5. Molecular formula: C30H31F3N6OS. Mole weight: 580.67.
CHMFL-BMX-078
CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor that exhibits an IC50 of 11 nM against BMX kinase and exhibits great selectivity over kinases such as BTK, JAK3, EGFR, and MAP2K7 that bore a structurally identical cysteine residue in BMX kinase. Uses: Protein kinase inhibitors. Synonyms: CHMFL-BMX-078; CHMFL-BMX 078; CHMFL BMX 078; CHMFLBMX078; 4-(methylamino)-2-[4-methyl-3-(prop-2-enoylamino)anilino]-N-[2-methyl-5-[(3,4,5-trimethoxybenzoyl)amino]phenyl]pyrimidine-5-carboxamide; 2-((3-acrylamido-4-methylphenyl)amino)-N-(2-methyl-5-(3,4,5-trimethoxybenzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide. CAS No. 1808288-51-8. Molecular formula: C33H35N7O6. Mole weight: 625.67.
CHMFL-EGFR-202
CHMFL-EGFR-202 is a potent and irreversible EGFR mutant kinase inhibitor with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively. It adopts the covalent ''DFG-in-C-helix-out'' inactive binding conformation with EGFR and has strong anti-proliferative effect on EGFR-mutation-driven non-small cell lung cancer (NSCLC) cell lines. Synonyms: 2-Propen-1-one, 1-[(3R)-3-[4-amino-3-[3-chloro-4-(2-pyridinylmethoxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-[(3R)-3-{4-Amino-3-[3-chloro-4-(2-pyridinylmethoxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}-1-piperidinyl]-2-propen-1-one. Grade: ≥95%. CAS No. 2089381-40-6. Molecular formula: C25H24ClN7O2. Mole weight: 489.96.
CHMFL-FLT3-122
CHMFL-FLT3-122 is a potent and selective FLT3 inhibitor (IC50 = 40 nM) with >10-fold and 170-fold selectivity for FLT3 over BTK kinase and c-KIT kinase. It causes apoptosis via cell cycle arrest in G0/G1 phase in vitro. In MV4-11 cell inoculated xenograft model, it suppressed tumor growth. Uses: Antitumor agent. Synonyms: CHMFL-FLT3-122; CHMFL FLT3 122; CHMFLFLT3122; 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone. CAS No. 1839150-56-9. Molecular formula: C26H29N7O2. Mole weight: 471.55.
CHMFL-KIT-033
CHMFL-KIT-033, a potent and selective c-KIT T670I mutant inhibitor (IC50 = 0.045 μM), is used for the treatment of gastrointestinal stromal tumors (GISTs). Synonyms: N-(3-Fluorophenyl)-N'-{3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}malonamide; Propanediamide, N1-(3-fluorophenyl)-N3-[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]-. Grade: ≥95%. CAS No. 2351801-41-5. Molecular formula: C23H18FN5O2. Mole weight: 415.42.
CHMFL-PI3KD-317
CHMFL-PI3KD-317 is a highly potent, selective, and orally active PI3K inhibitor (IC50: 6 nM) with the antiproliferative effects on cancer cells. It inhibits PI3K-mediated Akt T308 phosphorylation in Raji cells (EC50: 4.3 nM). CAS No. 2244992-76-3. Molecular formula: C21H24ClN5O3S2. Mole weight: 494.03.
CHMFL-PI4K-127
CHMFL-PI4K-127 is a potent and selective inhibitor of P. falciparum phosphatidylinositol 4-kinase (PfP14K). CHMFL-PI4K-127 was identified as a new potential drug candidate for malaria. Synonyms: GTPL11285. CAS No. 2377604-81-2. Molecular formula: C18H15ClN4O3S. Mole weight: 402.9.
Chol-5-en-24-al-3β-ol
Chol-5-en-24-al-3β-ol is a steroid compound and a derivative of Vitamin D3. (Extracted from patent US 4354972 A, Compound IX). Synonyms: Vitamin D3 derivative; (3β)-3-Hydroxychol-5-en-24-al; Chol-5-en-24-al, 3-hydroxy-, (3β)-. Grade: ≥95%. CAS No. 27460-33-9. Molecular formula: C24H38O2. Mole weight: 358.56.