MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Emicizumab | Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACE-910; RG6013. CAS No. 1610943-06-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9940. |  |
| Emiltatug | HY-P990918 is an VTCN1-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XMT-1604; XMT-1660 antibody. CAS No. 2855971-15-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990918. | |
| Emixustat hydrochloride | Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACU-4429 hydrochloride. CAS No. 1141934-97-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19720A. | |
| Emodepside | Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay 44-4400. CAS No. 155030-63-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101476. | |
| Emodin | Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Frangula emodin. CAS No. 518-82-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg. Product ID: HY-14393. | |
| Emodin-8-glucoside | Emodin-8-glucoside is an anthraquinone derivative that can be isolated from Aloe vera. Emodin-8-glucoside is the inhibitor for MAPK with an inhibition constant of 430.14 pM. Emodin-8-glucoside exhibits moderate inhibitory activity against rat lens aldose reductase (ALAR) and topoisomerases II with IC50s of 14.4 μM and 66 μM. Emodin-8-glucoside exhibits antioxidant, anti-inflammatory and anti-fibrotic activities. Emodin-8-glucoside can cross the blood brain barrier[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23313-21-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0311. | |
| Emodin (Standard) | Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Frangula emodin (Standard). CAS No. 518-82-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14393R. | |
| Emoghrelin | Emoghrelin, isolated from? Heshouwu Polygonum multiflorum, stimulates growth hormone secretion via activation of the ghrelin receptor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 928262-58-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12348. | |
| EMPA | EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 680590-49-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108682. | |
| Empagliflozin | Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI 10773. CAS No. 864070-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15409. | |
| Empagliflozin-d4 | Empagliflozin-d4 is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI 10773-d4. CAS No. 2749293-95-4. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-15409S. | |
| Empagliflozin (Standard) | Empagliflozin (Standard) is the analytical standard of Empagliflozin. This product is intended for research and analytical applications. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI 10773 (Standard). CAS No. 864070-44-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15409R. | |
| Empasiprubart | Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARGX-117. CAS No. 2579031-19-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990025. | |
| Empesertib | Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC50 of < 1 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 1161909. CAS No. 1443763-60-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12858. | |
| Emraclidine | Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator (WO2018002760, compound 11). Emraclidine can be used for the research of neurological diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CVL-231. CAS No. 2170722-84-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132812. | |
| Emricasan | Emricasan (PF 03491390) is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF 03491390; IDN-6556. CAS No. 254750-02-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-10396. | |
| Emrusolmin | Emrusolmin (Anle138b), an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein (α-syn). Emrusolmin strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Emrusolmin has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Emrusolmin blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anle138b. CAS No. 882697-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101855. | |
| EMT inhibitor-1 | EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. Uses: Scientific research. Category: Signaling pathways. CAS No. 1638526-21-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101275. | |
| EMT inhibitor-2 | EMT inhibitor-2 (Compound 1) inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes. EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2232228-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128859. | |
| Emtricitabine | Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BW1592. CAS No. 143491-57-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-17427. | |
| Emtricitabine (Standard) | Emtricitabine (Standard) is the analytical standard of Emtricitabine. This product is intended for research and analytical applications. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BW1592 (Standard). CAS No. 143491-57-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17427R. | |
| Emtricitabine triphosphate tetrasodium salt | Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However, Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427), a nucleoside reverse transcriptase inhibitor, targeting to HIV and HBV[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Emtricitabine triphosphate tetrasodium salt. CAS No. 1188407-46-6. Pack Sizes: 1 mg (100 mM * 17 μL in Water); 5 mg (100 mM * 87 μL in Water); 10 mg (100 mM * 174 μL in Water); 25 mg (100 mM * 435 μL in Water). Product ID: HY-131596B. | |
| Emugrobart | Emugrobart (GYM-329, RG6237, RG-70240) is a humanized IgG1κ antibody targeting myostatin (Myostatin; GDF8). Emugrobart binds to pro-myostatin and latent myostatin, blocking their cleavage into mature myostatin; it also has a clearance function, which transports bound myostatin for degradation and allows for cyclic reuse. Emugrobart enhances muscle strength in mouse models of muscle atrophy and increases muscle mass in cynomolgus monkeys. Emugrobart can be used in research on spinal muscular atrophy and facioscapulohumeral muscular dystrophy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GYM-329, RG6237, RG-70240. CAS No. 2922218-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990993. | |
| Emunkitug | HY-P990994 is an TNFRSF1B-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HFB-200301. CAS No. 2916519-48-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990994. | |
| Emvistegrast | Emvistegrast (GS-1427) is a quinolone derivative. Emvistegrast is also an inhibitor of α4β7 integrin. Emvistegrast can be used to investigate diseases mediated by α4β7 integrin, such as inflammatory bowel disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-1427. CAS No. 2417352-91-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-177080. | |
| Emzadirib | Emzadirib (RAD51-IN-2) is a RAD51 inhibitor extracted from patent WO2019/051465A1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CYT-0851; RAD51-IN-2. CAS No. 2301085-04-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111887. | |
| EN1033 | EN1033 is a covalent immune regulatory transcription factor 5/8 (IRF5/8) molecular glue degrader. EN1033 degrades IRF5 in a proteasome-dependent manner. EN1033 engages and degrades IRF8 more robustly and rapidly. EN1033 covalently targets C28 and C223 to destabilize and degrade IRF5 and IRF8 respectively, thereby inhibiting their pro-inflammatory transcriptional activity. EN1033 serves as a promising tool for the study of autoimmune and inflammatory disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2193367-28-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175759. | |
| EN106 | EN106 is a potent inhibitor of FEMIB. EN106 is a cysteine-reactive covalent ligand. EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1. EN106 reduces oxidative stress and rescues high glucose-induced impaired angiogenesis in HUVECs[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 757192-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W229874. | |
| EN1441 | EN1441 is a covalent degrader targeting the androgen receptor (AR) with an EC50 value of 4.2 μM and its truncated variant AR-V7. EN1441 selectively and potently degrades both AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 is promising for research of androgen-independent prostate cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2196448-47-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173626. | |
| EN219 | EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 380351-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115715. | |
| EN4 | EN4 is a covalent ligand that targets cysteine 171 (C171) of MYC. EN4 is selective for c-MYC over N-MYC and L-MYC. EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1197824-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134761. | |
| EN40 | EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2094547-67-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122577. | |
| EN460 | EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 (IC50 of 1.9 μM) interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 496807-64-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12837. | |
| EN523 | EN523 is a OTUB1 recruiter. EN523 targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2094893-05-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143345. | |
| EN6 | EN6 is a small-molecule in vivo autophagy activator that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase. EN6-mediated modification of ATP6V1A uncouples v-ATPase from Rag, leading to inhibition of mTORC1 signalling, increased lysosomal acidification, and activation of autophagy. EN6 also scavenges TDP-43 aggregates (causative agents of frontotemporal dementia) in a lysosome-dependent manner[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1808714-73-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128892. | |
| Enalapril | Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-421. CAS No. 75847-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-B0331. | |
| Enalaprilat | Enalaprilat (MK-422 anhydrous), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat can be used for the research of hypertension[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-422 anhydrous. CAS No. 76420-72-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0231A. | |
| Enalaprilat-d5 | Enalaprilat-d5 is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-422 d5. CAS No. 349554-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0231AS. | |
| Enalaprilat dihydrate | Enalaprilat dihydrate (MK-422), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat dihydrate can be used for the research of hypertension[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-422. CAS No. 84680-54-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-B0231. | |
| Enalapril maleate | Enalapril (MK-421) maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-421 maleate. CAS No. 76095-16-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0331A. | |
| Enalapril maleate (Standard) | Enalapril (maleate) (Standard) is the analytical standard of Enalapril (maleate). This product is intended for research and analytical applications. Enalapril (MK-421) maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-421 maleate (Standard). CAS No. 76095-16-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0331AR. | |
| (E)-Naringenin chalcone | (E)-Naringenin chalcone is an orally active anti-allergic agent. (E)-Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E)-Naringenin chalcone can improve adipocyte functions. (E)-Naringenin chalcone inhibits histamine release from rat peritoneal mast cell[1][2][4]. Uses: Scientific research. Category: Natural products. CAS No. 25515-46-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N3007A. | |
| Enarodustat | Enarodustat is a potent and orally active hypoxia-inducible factor prolyl hydroxylase inhibitor, with an EC50 of 0.22 μM. Enarodustat has the potential for renal anemia treatment. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JTZ-951; SAL0951. CAS No. 1262132-81-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109057. | |
| Enasidenib | Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-221. CAS No. 1446502-11-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18690. | |
| Enavatuzumab | Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo [1] [2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PDL192; ABT-361; Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody (enavatuzumab). CAS No. 1062149-33-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99361. | |
| Encaleret | Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 12 nM. Encaleret exerts its effect by inhibiting the excessive activity of functional gain-of-function CaSR variants, and can restore blood calcium levels, promote the secretion of parathyroid hormone, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. Encaleret can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CLTX-305; JTT-305; MK-5442. CAS No. 787583-71-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14401. | |
| Encelimab | Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2173096-82-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99922. | |
| Encenicline hydrochloride | Encenicline hydrochloride (EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: EVP-6124 hydrochloride. CAS No. 550999-74-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15430A. | |
| Encequidar | Encequidar (HM30181; HM30181A) is a potent and selective inhibitor of P-glycoprotein. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HM30181; HM30181A. CAS No. 849675-66-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13646. | |
| Encequidar mesylate | Encequidar mesylate (HM30181 mesylate; HM30181A mesylate) is a competitive and potent P-glycoprotein inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HM30181 mesylate; HM30181A mesylate. CAS No. 849675-87-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13646A. | |
| Enclomiphene citrate | Enclomiphene ((E)-Clomiphene) citrate is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene citrate can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-Clomiphene citrate; trans-Clomiphene citrate; Enclomifene citrate. CAS No. 7599-79-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118861A. | |
| Encorafenib | Encorafenib (LGX818) is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAFV600E (EC50=4 nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: LGX818. CAS No. 1269440-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15605. | |
| Endo-1,3-β-glucanase | Endo-1,3-β-glucanase (Lyticase) is an endoenzyme that can specifically cleave β-1,3-glycosidic bonds. Endo-1,3-β-glucanase recognizes and binds to β-1,3-glucan chains, catalyzing the cleavage of glycosidic bonds and hydrolyzing polysaccharides into oligosaccharides. Endo-1,3-β-glucanase eliminates vaginal Candida. Endo-1,3-β-glucanase can be used in the study of recurrent Candida vaginitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lyticase. CAS No. 9025-37-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-P3004. | |
| Endo-1,4-β-mannanase | Endo-1,4-β-mannanase is an important catalytic agent that randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose[1]. Uses: Scientific research. Category: Enzymes. CAS No. 37288-54-3. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-E70110. | |
| endo-BCN-NHS carbonate | endo-BCN-NHS carbonate is an elastin-like protein (ELP) modification reagent. endo-BCN-NHS carbonate can react with lysine residues in ELP to make ELP carry BCN groups, and then cross-link ELP through strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. endo-BCN-NHS carbonate promotes hydrogel formation. endo-BCN-NHS carbonate is mainly used in cell encapsulation related research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1426827-79-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-W035129. | |
| endo-BCN-O-PNB | endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263166-91-1. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g; 10 g. Product ID: HY-43581. | |
| endo-BCN-PEG2-NH2 | endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG2-NH2 contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263166-93-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W072752. | |
| endo-BCN-PEG3-mal | endo-BCN-PEG3-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG3-mal is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2141976-33-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133400. | |
| endo-BCN-PEG4-NHS ester | endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2252422-32-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140069. | |
| endo-BCN-PEG4-Val-Cit-PAB-MMAE | endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker conjugated with drug containing 4-unit PEG, which can be used for synthesizing antibody-drug conjugates (ADCs). endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2762519-08-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141155. | |
| endo-BCN-PEG8-NHS ester | endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1608140-48-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140070. | |
| Endoglycoceramidase II (EGCase II) | Endoglycoceramidase II (EGCase II) is an endo-β-glucosidase that releases intact glycans from ceramides in glycosphingolipids. Endoglycoceramidase II catalyzes the hydrolysis of β-glycosidic linkages between oligosaccharides and ceramides in various glycosphingolipids[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763216-34-6. Pack Sizes: 1 U. Product ID: HY-E70038. | |
| Endo H, Streptomyces picatus | Endo H, Streptomyces picatus (Endo-β-N-acetylglucosaminidase H), isolated from Streptomyces plicatus, hydrolyzes the central glycosidic bond of the β1, 4-di-N-acetylchitobiose core in asparagine-linked oligosaccharides[1]. Uses: Scientific research. Category: Enzymes. Alternative Names: Endo-β-N-acetylglucosaminidase H. CAS No. 37278-88-9. Pack Sizes: 500 U; 1 KU; 5 KU. Product ID: HY-E70131. | |
| Endomorphin 1 | Endomorphin 1, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 1 has antinociceptive properties[1][2][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 189388-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0185. | |
| Endoproteinase Asp-N (MS grade) | Endoproteinase Asp-N (MS grade) is a metalloprotease that can specifically cleave the N-terminal side of aspartyl and cysteic acid residues[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Asp-N. CAS No. 55576-49-3. Pack Sizes: 2 μg. Product ID: HY-E70196. | |
| Endoproteinase Lys-C | Endoproteinase Lys-C is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72561-05-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P3208. | |
| Endoproteinase Lys-C (MS grade) | Endoproteinase Lys-C (MS grade) is a hydrolase that cleaves peptide bonds at the carboxyl side of lysine residues. Endoproteinase Lys-C (MS grade) causes non-specific hydrolysis of peptide bonds linked to the carboxyl groups of non-lysine residues, resulting in partial cleavage at these sites[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72561-05-8. Pack Sizes: 20 μg. Product ID: HY-P3208B. | |
| Endoproteinase Lys-C (Tag-free) | Endoproteinase Lys-C (Tag-free) is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72561-05-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3208A. | |
| Endoproteinase Lys-N (MS grade) | Endoproteinase Lys-N (MS grade) is a protease that specifically hydrolyzes the N-terminal peptide bond of lysine fragments[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 91116-93-7. Pack Sizes: 20 μg. Product ID: HY-E70563. | |
| Endo S2, Streptococcus pyogenes | Endo-β-N-acetylglucosaminidase (Endo S2) is a key enzyme involved in the processing of free oligosaccharides in the cytosol. Endo-β-N-acetylglucosaminidase catalyzes hydrolysis of N-linked oligosaccharides[1]. Uses: Scientific research. Category: Enzymes. CAS No. 37278-88-9. Pack Sizes: 2 KU. Product ID: HY-E70069. | |
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