MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Eosin 5-isothiocyanate | Eosin 5-isothiocyanate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 60520-47-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0805. |  |
| Eosin Y | Eosin Y (Acid Red 87 free base) is a soluble acid red dye molecule. Eosin Y has a wide application in organic synthesis as a photoredox catalyst[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acid Red 87 free base. CAS No. 15086-94-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g. Product ID: HY-D0505. | |
| (E)-Osmundacetone | (E)-Osmundacetone is an inhibitor of the MAPK pathway. (E)-Osmundacetone inhibits the activation of the MAPK signaling pathway and restores the expression of PPARα/ACOX1. (E)-Osmundacetone abrogates abnormal cell proliferation, migration and liver metastasis induced by PTPRO silencing in colorectal cancer cells. (E)-Osmundacetone blocks OA-RD17-mediated activation of the MAPK signaling pathway, thereby reducing macrophage proliferation and migration. (E)-Osmundacetone is applicable to relevant research on colorectal cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123694-03-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N1966. | |
| EP2 receptor antagonist-1 | EP2 receptor antagonist-1 (compound 1) is a potent, reversible, and agonist dependent allosteric prostaglandin EP2 receptor antagonist. EP2 receptor antagonist-1 shows anti-inflammatory effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 848920-08-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145684. | |
| EP-3945 | EP-3945 is a potent agonist of Mas-related G protein-coupled receptor (MRGPR), more effective than the MRGPRD small molecule agonist β-Alanine (HY-N0230). MRGPR plays a crucial role in inflammatory pruritus and pain sensation. Additionally, MRGPR binds to Gq (MRGPRX2, MRGPRX4, MRGPRX1 couple with Gq; MRGPRX2, MRGPRD couple with Gi), with EP-3945 measured EC50 for Gq being 211.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3057176-00-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173003. | |
| EP4 receptor antagonist 1 | EP4 receptor antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy. EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC50s of 6.1 nM and 16.2 nM, respectively. IC50s >10 μM for human EP1, EP2,and EP3 receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2287259-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133123. | |
| EP4 receptor antagonist 2 | EP4 receptor antagonist 2 (Compound 8) is a tricyclic spiro-based EP4 receptor antagonist with microsomal stability[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1965316-82-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136645. | |
| Epacadostat | Epacadostat (INCB 024360) is a potent and selective indoleamine 2,3-dioxigenase 1 (IDO1) inhibitor with an IC50 of 71.8 nM[1]. Epacadostat can effectively reduce Trp metabolism, entailing increased activation and maturation of dendritic cells, and enhanced proliferation of effector T cells and natural killer cells (NKs), as well as attenuated Tregs expansion. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INCB 024360. CAS No. 1204669-58-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-15689. | |
| Epacadostat (Standard) | Epacadostat (Standard) is the analytical standard of Epacadostat. This product is intended for research and analytical applications. Epacadostat (INCB 024360) is a potent and selective indoleamine 2,3-dioxigenase 1 (IDO1) inhibitor with an IC50 of 71.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INCB 024360 (Standard). CAS No. 1204669-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15689R. | |
| Epacmarstobart | Epacmarstobart (FSI-189; GS-0189) is a chimeric humanized IgG1κ antibody targeting the mouse signal regulatory protein SIRPA. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: FSI-189; GS-0189. CAS No. 2518200-89-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990019. | |
| Epalrestat | Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ONO2235. CAS No. 82159-09-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-66009. | |
| Epalrestat (Standard) | Epalrestat (Standard) is the analytical standard of Epalrestat. This product is intended for research and analytical applications. Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ONO2235 (Standard). CAS No. 82159-09-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-66009R. | |
| Epaminurad | Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UR-1102; URC-102. CAS No. 1198153-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111345. | |
| Epcoritamab | Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GEN3013. CAS No. 2134641-34-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99931. | |
| (E)-p-Coumaryl alcohol | (E)-p-Coumaryl alcohol is a metabolite of coumarin that has significant cytotoxicity. (E)-p-Coumaryl alcohol can be isolated from Alpinia officinarum and Rhodiola rosea and can be used for inflammation research[1]. Uses: Scientific research. Category: Natural products. Alternative Names: (E)-p-Hydroxycinnamyl alcohol. CAS No. 20649-40-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N3102A. | |
| Epetraborole hydrochloride | Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor (IC50=0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK2251052 hydrochloride. CAS No. 1234563-16-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12479A. | |
| EphA2 agonist 1 | EphA2 agonist 1 (Compound 7bg) is a potent EphA2 receptor agonist. EphA2 agonist 1 shows great potency and selectivity toward EphA2 overexpressed glioblastoma cells and stimulates EphA2 phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2611459-57-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147637. | |
| EphA2 antagonist 1 | EphA2 antagonist 1 (4b) is a bile acid conjugate and an ephrin type-A receptor 2 (EPHA2) inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1428095-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-169849. | |
| EphB1-IN-1 | EphB1-IN-1 (Compound 1) is a potent EphB1 inhibitor with IC50s of 3.0, 15 and 220 nM against EphB1G703C, EphB1T697G and EphB1WT, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1980036-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115481. | |
| EPI-7170 | EPI-7170, a ralaniten analogue, is a potent androgen receptor N-terminal structural domain antagonist that blocks the transcriptional activity of full-length AR (FL-AR) and AR splice variants (AR-Vs). EPI-7170 has antitumor effects against enzalutamide resistant castration-resistant prostate cancer (CRPC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2139288-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150102. | |
| EPI-743 | EPI-743 (Vatiquinone; α-Tocotrienol quinone; PTC-743; NCT04378075) is a potent cellular oxidative stress protectant, inhibits ferroptosis in cells, which could be used for the study for mitochondrial diseases. EPI-743 is a synthetic analog of vitamin E with oral activity, targets repletion of reduced intracellular glutathione[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Tocotrienol quinone; PTC-743; Vatiquinone; NCT04378075. CAS No. 1213269-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16772. | |
| (-)-Epiafzelechin | (-)-Epiafzelechin shows potent antioxidant activity with EC50 20.9 μM (EC50=5.7 μg/mL)[1]. Uses: Scientific research. Category: Natural products. CAS No. 24808-04-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0943. | |
| Epibrassinolide | Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants[1]. Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 24-Epibrassinolide; B1105; BP55. CAS No. 78821-43-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0848. | |
| (-)-Epicatechin | (-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Epicatechol; Epicatechin; epi-Catechin. CAS No. 490-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0001. | |
| (+)-Epicatechin | (+)-Epicatechin (Dexepicatechin) is a catechin and a polyphenol, with antioxidant activities[1]. Uses: Scientific research. Category: Natural products. Alternative Names: Dexepicatechin; (+)-Epicatechol. CAS No. 35323-91-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0001A. | |
| (-)-Epicatechin gallate | (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 7.5 μM[1][2]. (-)-Epicatechin gallate is a GLUT1 and GLUT5 inhibitor. (-)-Epicatechin gallate decreases cell growth of GLUT5-expressing hxt0 yeast cells[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate. CAS No. 1257-08-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0002. | |
| (-)-Epicatechin gallate (Standard) | (-)-Epicatechin gallate (Standard) is the analytical standard of (-)-Epicatechin gallate. This product is intended for research and analytical applications. (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 7.5 μM. (-)-Epicatechin gallate is a GLUT1 and GLUT5 inhibitor. (-)-Epicatechin gallate decreases cell growth of GLUT5-expressing hxt0 yeast cells[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epicatechin gallate(Standard); ECG(Standard); (-)-Epicatechin 3-O-gallate (Standard). CAS No. 1257-08-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0002R. | |
| (-)-Epicatechin (Standard) | (-)-Epicatechin (Standard) is the analytical standard of (-)-Epicatechin. This product is intended for research and analytical applications. (-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Epicatechol(Standard); Epicatechin(Standard); epi-Catechin (Standard). CAS No. 490-46-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0001R. | |
| Epicoprostanol | Epicoprostanol is the compound found in adipocere[1]. Uses: Scientific research. Category: Natural products. Alternative Names: 5β-Cholestan-3α-ol. CAS No. 516-92-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W127498. | |
| (+)-Epieudesmin | (+)-Epieudesmin is an antineoplastic agent. (+)-Epieudesmin has marginal cancer cell line inhibitory activities. (+)-Epieudesmin inhibits the growth of Gram-negative pathogen[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60102-89-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N12262. | |
| (-)-Epigallocatechin | (-)-Epigallocatechin (Epigallocatechin) is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epigallocatechin; L-Epigallocatechin. CAS No. 970-74-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-N0225. | |
| (-)-Epigallocatechin-3-O-(4-O-methyl)gallate | (-)-Epigallocatechin-3-O-(4-O-methyl)gallate is an orally active catechin derivative found in Taiwanese oolong tea. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can inhibit histamine release and exhibits anti-inflammation and anti-allergic effect. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can be used for the researches of immunology and inflammation, such as type I allergic[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EGCG4Me. CAS No. 224434-07-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N15663. | |
| (-)-Epigallocatechin Gallate | (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EGCG; Epigallocatechol Gallate. CAS No. 989-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13653. | |
| (-)-Epigallocatechin Gallate (Standard) | (-)-Epigallocatechin Gallate (Standard) is the analytical standard of (-)-Epigallocatechin Gallate. This product is intended for research and analytical applications. (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EGCG(Standard); Epigallocatechol Gallate (Standard). CAS No. 989-51-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13653R. | |
| (-)-Epigallocatechin (Standard) | (-)-Epigallocatechin (Standard) is the analytical standard of (-)-Epigallocatechin. This product is intended for research and analytical applications. (-)-Epigallocatechin (Epigallocatechin) is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epigallocatechin(Standard); L-Epigallocatechin (Standard). CAS No. 970-74-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0225R. | |
| Epimedin A | Epimedin A, one of the main flavonoid active components in Herba Epimedii, is orally active. Epimedin A can inhibit osteoclastogenesis, differentiation, and bone resorption. Epimedin A also possesses anti-inflammatory activity. Epimedin A can be used in the research of osteoporosis and inflammatory diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 110623-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N0257. | |
| Epimedin A1 | Epimedin A1 is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines. Uses: Scientific research. Category: Natural products. Alternative Names: Hexandraside F. CAS No. 140147-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0258. | |
| Epiquinamine | Epiquinamine, an alkaloid, has amoebicidal activity (IC50: 12.9 μg/mL)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Conquinamine. CAS No. 464-86-8. Pack Sizes: 1 mg. Product ID: HY-N3620. | |
| Epirubicin | Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase[1]. Epirubicin inhibits DNA and RNA synthesis. Epirubicin is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4'-Epidoxorubicin. CAS No. 56420-45-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13624. | |
| Epirubicin hydrochloride | Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase[1]. Epirubicin hydrochloride inhibits DNA and RNA synthesis. Epirubicin hydrochloride is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4'-Epidoxorubicin hydrochloride. CAS No. 56390-09-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13624A. | |
| Epitalon | Epitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epithalon; Epithalamin. CAS No. 307297-39-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1149. | |
| Epitheaflagallin 3-O-gallate | Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102067-92-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4298. | |
| Epitinib | Epitinib (HMPL-813) is a selective, orally active, blood-brain barrier-permeable EGFR tyrosine kinase inhibitor. Epitinib is applicable to research on EGFRT790M-positive non-small cell lung cancer with brain metastasis and advanced solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMPL-813. CAS No. 1203902-67-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139300. | |
| EPI-X4 | EPI-X4 (hSA408-423 peptide) is an antagonist for C-X-C motif chemokine receptor 4 (CXCR4) with IC50 of 8.6 μM. EPI-X4 blocks the CXCL12-mediated signaling, inhibits chemokine-mediated migration and invasion of leukemia cell. EPI-X4 exhibits anti-inflammatory activity in mouse model. EPI-X4 exhibits antiviral activity against CXCR4-tropic HIV with IC50 of 8.6 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: hSA(408-423) peptide. CAS No. 930280-31-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10415. | |
| Eplerenone | Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epoxymexrenone. CAS No. 107724-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0251. | |
| Eplontersen | Eplontersen is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1637600-16-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148089. | |
| Epoprostenol sodium | Epoprostenol sodium (Prostaglandin I2) sodium salt, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prostaglandin I2 sodium salt; Prostacyclin sodium salt; Flolan. CAS No. 61849-14-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0126A. | |
| Epothilone A | Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epo A. CAS No. 152044-53-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13503. | |
| Epothilone B | Epothilone B is a microtubule stabilizer (MSA) with a Ki of 0.71μM, and is a MSA with blood-brain barrier permeability. Epothilone B acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EPO 906; Patupilone. CAS No. 152044-54-7. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17029. | |
| Epoxiconazole | Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 133855-98-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119683. | |
| Epoxidized soya bean oil | Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Soybean oil epoxide. CAS No. 8013-7-8. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W093282. | |
| Epoxomicin | Epoxomicin (BU-4061T) is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier. Epoxomicin has strongly antitumor and anti-inflammatory activity[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BU-4061T. CAS No. 134381-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 μg; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13821. | |
| EpoY | EpoY (SD-142) acts as an irreversible inhibitor of the brain's primary tubulin tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition leads to significant differentiation defects and has been linked to underlying issues associated with cancer and cardiomyopathies. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SD-142. CAS No. 245660-13-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148542. | |
| EPQpYEEIPIYL | EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147612-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3279. | |
| Epratuzumab | Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkins lymphomas (NHL) and certain autoimmune diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Antibody hLL 2; AMG-412. CAS No. 205923-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99289. | |
| Eprazinone dihydrochloride | Eprazinone dihydrochloride is a gent with mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties. Eprazinone dihydrochloride is a neurokinin 1 receptor (NK1R) ligand. Eprazinone dihydrochloride has the potential for chronic bronchitis treatment that improved pulmonary function and arterial partial pressure of oxygen[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10402-53-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B2078A. | |
| Eprenetapopt | Eprenetapopt (APR-246) is a first-in-class, small molecule that restores wild-type p53 functions in TP53-mutant cells. Eprenetapopt triggers apoptosis in tumor cells. Eprenetapopt also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APR-246; PRIMA-1Met. CAS No. 5291-32-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19980. | |
| Epristeride | Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ONO-9302; SKF105657. CAS No. 119169-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-107385. | |
| Eprosartan mesylate | Eprosartan mesylate (SKF-108566J) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan mesylate binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF-108566J. CAS No. 144143-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15834A. | |
| ε-Caprolactone-d6 | ε-Caprolactone-d6 is the deuterium labeled ε-Caprolactone[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219802-08-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W015891S. | |
| ε-Poly-L-lysine (MW 3800-4200) | Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200). CAS No. 28211-04-3. Pack Sizes: 5 g; 10 g; 25 g; 50 g. Product ID: HY-W250308. | |
| Epsilon-V1-2 | Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ε-V1-2; EAVSLKPT. CAS No. 182683-50-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0154. | |
| ε-?Viniferin | ε-Viniferin (epsilon-Viniferin), the dimer of Resveratrol and can be isolated from Vitis vinifera, displays a potent inhibitory for all the CYP activities, with Ki values from 0.5-20 μM. ε-Viniferin possesses potent antioxidant, anti-inflammatory, anti-diabetic, and anti-neurodegenerative capacity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: epsilon-Viniferin. CAS No. 62218-08-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3841. | |
| Eptifibatide | Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 188627-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0686. | |
| Eptifibatide acetate | Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 881997-86-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0686B. | |
| Eptinezumab | Eptinezumab (ALD-403) is a human monoclonal antibody targeting the α and β subtypes of human calcitonin gene-related peptide (CGRP). Eptinezumab binds to the CGRP ligand and blocks its binding to endogenous CGRP receptors, thereby inhibiting receptor activation. Eptinezumab can be used in research related to migraine[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALD-403. CAS No. 1644539-04-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99017. | |
| Epyrifenacil | Epyrifenacil is a protoporphyrinogen oxidase (PPO) inhibiting herbicide, potently targeting the PPO2 isoform from weeds such as Amaranthus palmeri with an IC50 of 0.637 nM. Epyrifenacil also inhibits liver mitochondrial PPO across species, with IC50 values of 2.2 nM (mouse), 2.6 nM (rat), 12.1 nM (rabbit), 7.6 nM (dog), and 10.2 nM (human). Epyrifenacil induces liver tumor development in mice. Epyrifenacil can be used for weed control, and also used as a tool compound in toxicological research to study the mechanism of PPO inhibition, chemical-induced hepatotoxicity, and the mode of action of non-genotoxic carcinogens in rodents[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 353292-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-139838. | |
| EPZ004777 | EPZ004777 is an effective and selective DOT1L inhibitor, with IC50 being 0.4 nM. EPZ004777 reduces the levels of H3K79me2 and H3K79me1, significantly down-regulating the expression of HOXA9 and MEIS1. EPZ004777 selectively inhibits the proliferation of MLL rearrangement cells and promotes the differentiation and subsequent apoptosis (apoptosis) of leukemia cells. EPZ004777 can be used for the study of leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1338466-77-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15227. | |
| EPZ004777 hydrochloride | EPZ004777 hydrochloride is an effective and selective DOT1L inhibitor, with IC50 being 0.4 nM. EPZ004777 hydrochloride reduces the levels of H3K79me2 and H3K79me1, significantly down-regulating the expression of HOXA9 and MEIS1. EPZ004777 hydrochloride selectively inhibits the proliferation of MLL rearrangement cells and promotes the differentiation and subsequent apoptosis (apoptosis) of leukemia cells. EPZ004777 hydrochloride can be used for the study of leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1380316-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15227A. | |
| EPZ005687 | EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, and has 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases. Uses: Scientific research. Category: Signaling pathways. CAS No. 1396772-26-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15555. | |
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