MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ethephon | Ethephon is a plant growth regulator[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 16672-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-W131845. |  |
| Ethidium homodimer | Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EthD-1. CAS No. 61926-22-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-D0093. | |
| Ethinylestradiol | Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethynyl estradiol; 17α-Ethynylestradiol. CAS No. 57-63-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0216. | |
| Ethiprole | Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 181587-01-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-120425. | |
| Ethopropazine hydrochloride | Ethopropazine (Isothazine) hydrochloride is a potent and selective BChE inhibitor, a poor AChE inhibitor and a non-selective mAChR and NMDA antagonist. Ethopropazine hydrochloride has anticholinergic, antihistamine, antiadrenergic actions and properties. Ethopropazine hydrochloride alleviates thermal hyperalgesia in a dose dependent manner. Ethopropazine hydrochloride can be used for the research of Parkinsons disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Isothazine. CAS No. 1094-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107922. | |
| Ethosuximide | Ethosuximide, a widely prescribed anti-epileptic agent, improves the phenotypes of multiple neurodegenerative disease models and blocks the low voltage activated T-type calcium channel. Uses: Scientific research. Category: Signaling pathways. CAS No. 77-67-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-B1378. | |
| Ethoxylated hydrogenated castor oil | Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated. CAS No. 61788-85-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-126403. | |
| (Ethoxymethyl)benzene | (Ethoxymethyl)benzene is an endogenous metabolite. Uses: Scientific research. Category: Signaling pathways. CAS No. 539-30-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W017613. | |
| Ethoxzolamide | Ethoxzolamide is a carbonic anhydrase inhibitor with Ki of 1 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Redupresin; L-643786; PNU-4191. CAS No. 452-35-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1480. | |
| Ethyl 2-chloropyrimidine-5-carboxylate | Ethyl 2-chloropyrimidine-5-carboxylate can be used for synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 89793-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-W003995. | |
| Ethyl 2-cyano-2-(hydroxyimino)acetate | Ethyl 2-cyano-2-(hydroxyimino) acetate (Oxyma) is a peptide coupling additive. Ethyl 2-cyano-2-(hydroxyimino) acetate suppresses racemization during peptide coupling and improves the coupling efficiency of both solution-phase and solid-phase peptide synthesis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3849-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g. Product ID: HY-41456. | |
| Ethyl acetoacetate-d3 | Ethyl acetoacetate-d3 is the deuterium labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[1][2][3]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1565868-21-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-Y1093S4. | |
| Ethyl α-D-glucopyranoside | Ethyl α-D-glucopyranoside (Ethyl α-D-glucoside) is a glycoside that can be found in the seeds of Vaccaria segetalis. Ethyl α-D-glucopyranoside can be used for research on inflammation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethyl α-D-glucoside. CAS No. 19467-01-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N4281. | |
| Ethyl cellulose | Ethyl cellulose is a derivative of cellulose. Ethyl cellulose is a non-toxic, biodegradable polymer. Ethyl cellulose has unique properties such as oil gel formation, active ingredient delivery and film formation. Ethyl cellulose can be used as a pharmaceutical excipient, such as a coating agent, flavoring agent, tablet filler, etc. Ethyl cellulose can be used to prepare nanoparticles for active compound delivery[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethyl cellulose N-200. CAS No. 9004-57-3. Pack Sizes: 100 g; 500 g; 1 k g. Product ID: HY-W115746. | |
| Ethyl cinnamate | Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103-36-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 250 g; 500 g. Product ID: HY-Y0121. | |
| Ethylene glycol-13C2 | Ethylene glycol-13C2 is the 13C labeled Ethylene glycol[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 104700-12-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0338S1. | |
| Ethylene glycol,98% | Ethylene glycol is an organic compound that is often used as an antifreeze agent and coolant. Ethylene glycol lowers the freezing point by forming hydrogen bonds with water molecules, exerting antifreeze activity. Ethylene glycol is also used as a raw material in the synthesis of polymers such as polyester fibers and polyurethanes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 107-21-1. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 500 g. Product ID: HY-Y0338. | |
| Ethylene glycol-d4 | Ethylene glycol-d4 is the deuterium labeled Ethylene glycol[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2219-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-Y0338S2. | |
| Ethylene glycol dimethacrylate | Ethylene glycol dimethacrylate is a diester formed by the condensation of Ethylene glycol (HY-Y0338) and Methacrylic acid. Ethylene glycol dimethacrylate is a cross-linking agent for polymers. Ethylene glycol dimethacrylate increases Apoptosis, GPx4, SOD2, ROS. Ethylene glycol dimethacrylate is cytotoxic and genotoxic. Ethylene glycol dimethacrylate exhibits cross-linking activity, enhancing the mechanical properties and stability of materials[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 97-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 g; 100 g; 250 g; 500 g. Product ID: HY-W014940. | |
| Ethyl gallate | Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide. Uses: Scientific research. Category: Signaling pathways. CAS No. 831-61-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g. Product ID: HY-N0525. | |
| Ethylhexylglycerin | Ethylhexylglycerin has antimicrobial activity, inhibiting the growth of Acinetobacter spp., Pseudomonas aeruginosa complex, and Stenotrophomonas maltophilia. Ethylhexylglycerin can cause pigmentary contact dermatitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 70445-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g; 1 k g. Product ID: HY-W099729. | |
| Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside | Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside (EPS; pNP-G7) serves as a substrate for α-amylase. In the presence of an auxiliary enzyme such as α-glucosidase (α-glucosidase), Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside is degraded by amylase (Amylase) to release a chromophore, enabling the measurement of amylase activity. Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside is applicable for the diagnosis of pancreatitis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: pNP-G7. CAS No. 96597-16-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-112835. | |
| Ethyl Lauroyl Arginate Hydrochloride | Ethyl Lauroyl Arginate Hydrochloride is an arginine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60372-77-2. Pack Sizes: 1 g; 5 g. Product ID: HY-W099595. | |
| Ethyl nitroacetate | Ethyl nitroacetate is a nitro compound. As an important intermediate in organic synthesis, Ethyl nitroacetate can be used for the synthesis of other active compounds[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 626-35-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g. Product ID: HY-76486. | |
| Ethyl pyruvate | Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an HMGB1 release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 617-35-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-Y1362. | |
| Ethyl rosmarinate | Ethyl rosmarinate is a phenolic compound that can be isolated from Lycopus lucidus. Ethyl rosmarinate has antioxidative activity. Ethyl rosmarinate inhibits lung inflammation[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 174591-47-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N10610. | |
| Ethynyl Estradiol-d4 | Ethynyl Estradiol-d4 is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 17α-Ethynylestradiol-d4; Ethynylestradiol-d4. CAS No. 350820-06-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-B0216S. | |
| Eticlopride hydrochloride | Eticlopride hydrochloride, a selective dopamine D2?like receptor antagonist, exhibits high affinity for dopamine D2, α1-adrenergic, α2-adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Eticlopride hydrochloride is an antipsychotic agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 97612-24-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-103413. | |
| Etiocholanolone | Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity[1]. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABAA receptor than its enantiomer form[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5β-Androsterone. CAS No. 53-42-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113320. | |
| Etiracetam | Etiracetam is a racetam-class nootropic agent. Etiracetam enhances learning and memory in both normal and amnesic rats. Etiracetam can be used in studies related to memory retrieval disorders and amnesic diseases such as Alzheimer's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCB 6474. CAS No. 33996-58-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg. Product ID: HY-B0106A. | |
| ETN029 | ETN029 (MC339) is a selective DLL3 ligand. ETN029 labeled with 225Ac has dose-dependent cytotoxicity in SCLC, NEPC and metastatic melanoma cells and increases the phosphorylation of H2AX expression. ETN029 labeled with 177Lu shows rapid uptake persistent tumor retention and favorable tumor-to-kidney ratio. ETN029 can be used for cancers like SCLC and NEPC imaging and research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC339. CAS No. 3066864-32-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-W1126504. | |
| ETNK-IN-1 | ETNK-IN-1 (Compound 7) is an inhibitor of ethanolamine kinase (ETNK) with an IC50 value of ≥ 5 μM, which can be used in research for insecticide development[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 301330-94-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169547. | |
| Etodolac | Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that can cross the blood-brain barrier and is a non-selective inhibitor of COX (IC50=53.5 nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: AY-24236. CAS No. 41340-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-76251. | |
| Etofenamate | Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 30544-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-17361. | |
| Etokimab | Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Antibody ANB 020. CAS No. 2022981-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99018. | |
| Etomoxir | Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-(+)-Etomoxir. CAS No. 124083-20-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50202. | |
| Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-(+)-Etomoxir sodium salt. CAS No. 828934-41-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50202A. | |
| Etonogestrel | Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs[1]. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs)[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Oxodesogestrel; 3-keto-Desogestrel. CAS No. 54048-10-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0652. | |
| Etoposide | Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VP-16; VP-16-213. CAS No. 33419-42-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-13629. | |
| Etoposide phosphate | Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Etoposide phosphate is the phosphate ester proagent of etoposide and is considered as active equivalent to Etoposide. Etoposide phosphate induces cell cycle arrest, apoptosis, and autophagy. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMY-40481. CAS No. 117091-64-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13630. | |
| Etoposide (Standard) | Etoposide (Standard) is the analytical standard of Etoposide. This product is intended for research and analytical applications. Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VP-16 (Standard); VP-16-213 (Standard). CAS No. 33419-42-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-13629R. | |
| Etoricoxib | Etoricoxib (MK-0663) is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor. Etoricoxib can cross the blood-brain barrier, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0663; L-791456. CAS No. 202409-33-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15321. | |
| ETP-46464 | ETP-46464 is an effective mTOR and ATR inhibitor with IC50s of 0.6 and 14 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1345675-02-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15521. | |
| Etrasimod | Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an IC50 value of 1.88 nM in CHO cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APD334. CAS No. 1206123-37-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12789. | |
| Etravirine | Etravirine (R165335; TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R165335; TMC125. CAS No. 269055-15-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-90005. | |
| Etrolizumab | Etrolizumab (rhuMAb Beta7) is a gut-selective, anti-β7 integrin monoclonal antibody. Etrolizumab is specific targeting of the β7 subunit of α4β7 and αEβ7 integrins with Ki values of 18 nM and 1800 pM for Human α4β7 and Human αEβ7-293, respectively. Etrolizumab can be used in research of inflammatory bowel disease (IBD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: rhuMAb Beta7; RG7413; PRO145223. CAS No. 1044758-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9984. | |
| Etrumadenant | Etrumadenant (AB928) is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. Etrumadenant relieves adenosine-mediated immune suppression. Etrumadenant has immunomodulatory and antitumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AB928. CAS No. 2239273-34-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129393. | |
| Eudesmin | Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Eudesmin; Eudesmine; (-)-Eudesmine. CAS No. 526-06-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2357. | |
| Eugenin | Eugenin is a chromone that can be isolated from Formosan Peucedanum japonicum and has an effective antiplatelet aggregation effect. In addition, Eugenin has certain cytotoxicity against tumor cells[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 480-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-33351. | |
| Eugenol (Standard) | Eugenol (Standard) is the analytical standard of Eugenol. This product is intended for research and analytical applications. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation. Uses: Scientific research. Category: Signaling pathways. CAS No. 97-53-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0337R. | |
| EUK-134 | EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. EUK-134 is a superoxide dismutase (SOD) mimetics (SODm) with catalase activity. EUK-134 is a mitoprotective antioxidant. EUK-134 reduces the expression of NF-κB, MDA level, and protein carbonylation in H9C2 cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81065-76-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100594. | |
| Eupafolin | Eupafolin (Nepetin) (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activities. Eupafolin inhibits IL-6, IL-8 and MCP-1 secretion with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively in ARPE-19 cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nepetin; 6-Methoxyluteolin. CAS No. 520-11-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N2572. | |
| Eupatilin | Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities. Uses: Scientific research. Category: Signaling pathways. CAS No. 22368-21-4. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0783. | |
| Euphol | Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 514-47-6. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0313. | |
| Eurycomalactone | Eurycomalactone is an active quassinoid could be isolated from Eurycoma longifolia Jack. Eurycomalactone is a potent NF-κB inhibitor with an IC50 value of 0.5 μM. Eurycomalactone inhibits protein synthesis and depletes cyclin D1. Eurycomalactone enhances radiosensitivity through arrest cell cycle at G2/M phase and delayed DNA double-strand break repair. Eurycomalactone inhibits the activation of AKT/NF-κB signaling, induces apoptosis and enhances chemosensitivity to Cisplatin (HY-17394)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23062-24-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4327. | |
| Evans Blue | Evans Blue (Direct Blue 53) is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor. Evans Blue has a strong affinity towards serum albumin, making it a high molecular weight protein tracer. Evans Blue is also used to study BBB (blood-brain barrier) permeability[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Direct Blue 53; T-1824; C.I. 23860. CAS No. 314-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B1102. | |
| Evatanepag | Evatanepag (CP-533536) is a non-prostanoid, potent and selective EP2 receptor agonist. Evatanepag can induce local bone formation in vivo. Evatanepag can be used in the research of fractures, bone defects, asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-533536 free acid. CAS No. 223488-57-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14839. | |
| Evenamide | Evenamide (NW-3509) is an orally available voltage-gated sodium channel (VGSC) blocker (Ki=0.4 μM) for the research of schizophrenia. Evenamide shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NW-3509. CAS No. 1092977-61-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17612. | |
| Everolimus | Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective, orally active, blood-brain barrier-permeable mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD001; SDZ-RAD. CAS No. 159351-69-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10218. | |
| Everolimus-d4 | Everolimus-d4 is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD001-d4; SDZ-RAD-d4. CAS No. 1338452-54-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10218S. | |
| Evinacumab | Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194. | |
| Evixapodlin | Evixapodlin (GS-4224) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM. Evixapodlin has anticancer and antiviral functions[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-4224; PD-1/PD-L1-IN 7. CAS No. 2374856-75-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138407. | |
| Evobrutinib | Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M2951; MSC2364447C. CAS No. 1415823-73-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101215. | |
| Evocalcet | Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KHK7580. CAS No. 870964-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17613. | |
| Evodenoson | Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenosons primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenosons protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATL 313; DE 112. CAS No. 844873-47-8. Pack Sizes: 1 mg. Product ID: HY-105017. | |
| Evodiamine | Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor. Uses: Scientific research. Category: Natural products. Alternative Names: (+)-Evodiamine; d-Evodiamine. CAS No. 518-17-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-N0114. | |
| Evofosfamide | Evofosfamide (TH-302) is a hypoxia-activated proagent with IC50 of 10 μM and 1000 μM in hypoxia (N2) and normoxia (21% O2), respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TH-302. CAS No. 918633-87-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10535. | |
| Evogliptin tartrate | Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DA-1229 tartrate. CAS No. 1222102-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117985B. | |
| Evolocumab | Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG 145. CAS No. 1256937-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9930. | |
| Evorpacept | Evorpacept (ALX148) is a high-affinity CD47-blocking fusion protein with an inactive human immunoglobulin Fc region. Evorpacept binds to CD47, blocks the interaction of the CD47-SIRPα immune checkpoint, and inhibits the binding of wild-type SIRPα to CD47. Evorpacept is applicable to research related to acute myeloid leukemia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALX148. CAS No. 2484949-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99950. | |
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