MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| FEN1-IN-2 | FEN1-IN-2 (compound 20) is a flap endonuclease 1 (FEN1) inhibitor, with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 824983-94-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122695. |  |
| FEN1-IN-4 | FEN1-IN-4 (Compound 2) is a human flap endonuclease-1 (hFEN1) inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1995893-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136485. | |
| FEN1-IN-7 | FEN1-IN-7 (compound 16) is a selective inhibitor of Flap endonuclease-1 (FEN1, IC50=18 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-7 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC50 value of 3.04 μM. FEN1-IN-7 increases the cellular sensitivity of cancer cells to potent DNA alkylating agents or methylating agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 824983-90-6. Pack Sizes: 1 mg. Product ID: HY-153792. | |
| FEN1-IN-SC13 | FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor with antitumor activity. FEN1-IN-SC13 interferes with DNA replication and repair in vitro and in cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098776-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145758. | |
| Fenbendazole | Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 43210-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0413. | |
| Fenbendazole-d3 | Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228182-47-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-B0413S. | |
| Fenclonine | Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research[1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 4-Chloro-DL-phenylalanine; PCPA; CP-10188. CAS No. 7424-00-2. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g. Product ID: HY-B1368. | |
| Fendiline hydrochloride | Fendiline hydrochloride, a diphenylalkylamine type of antianginal agent, is an L-type calcium channel blocker (IC50 of 17 μM). Fendiline hydrochloride is also a selective K-Ras inhibitor, and has no effect on H-Ras and N-Ras. Fendiline hydrochloride inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM), inhibits K-Ras signal output and blocks the proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras. Fendiline hydrochloride is a STING agonist and is able to inhibit the growth of multiple refractory cold tumors (MC38, CT26 and B16F10)[1][2][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13636-18-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-B0984. | |
| Fenebrutinib | Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with Kis of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0853. CAS No. 1434048-34-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19834. | |
| Fenitrothion | Fenitrothion is a broad-spectrum and orally active insecticide/acaricide. Fenitrothion inhibits cholinesterase, AMPKα and IRS1/PI3K/AKT. Fenitrothion causes Apoptosis, reduces SOD activity. Fenitrothion shows insecticidal effect against Rhyzopertha dominica and Tribolium castaneum adults. Fenitrothion is widely used in cotton crops, vegetable crops, fruit crops and field crops, especially rice. Fenitrothion can be used for brain and spleen toxicology studies[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 122-14-5. Pack Sizes: 100 mg; 250 mg. Product ID: HY-B1885. | |
| Fenofibrate | Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 49562-28-9. Pack Sizes: 10 mM * 1 mL in DMSO; 200 mg; 5 g; 10 g. Product ID: HY-17356. | |
| Fenofibric acid | Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FNF acid. CAS No. 42017-89-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0760. | |
| Fenoldopam mesylate | Fenoldopam mesylate (SKF-82526) is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC50=0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fenoldopam methanesulfonate; SKF-82526 mesylate. CAS No. 67227-57-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0735A. | |
| Fenoprofen | Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LILLY-53858. CAS No. 29679-58-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-B1456A. | |
| Fenpicoxamid | Fenpicoxamid is a new fungicide. Fenpicoxamid inhibits the growth of the fungus Z. tritici with an EC50 value of 0.051 mg/L[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XDE 777. CAS No. 517875-34-2. Pack Sizes: 5 mg. Product ID: HY-122298. | |
| Fenpropathrin | Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively[1]. Uses: Scientific research. Category: Induced disease models products. CAS No. 39515-41-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-123178. | |
| Fenpropimorph | Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67564-91-4. Pack Sizes: 10 mM * 1 mL in DMF; 1 mg; 5 mg; 10 mg. Product ID: HY-128033. | |
| Fenretinide | Fenretinide (4-HPR) is a synthetic retinoid deriverative, binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-HPR; ISLA-101. CAS No. 65646-68-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15373. | |
| Fenticonazole Nitrate | Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REC 15-1476. CAS No. 73151-29-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0359. | |
| Fenvalerate | Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51630-58-1. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-B2006. | |
| Fepixnebart | Fepixnebart (LY3016859) is a humanized monoclonal hIgG4 antibody, which binds and neutralizes only TGFα and epiregulin with high affinity. Fepixnebart can be used for the study of diabetic nephropathy and broad-spectrum chronic pain, including diabetic peripheral neuropathic pain (DPNP), signs and symptoms of osteoarthritis (OA), and chronic low back pain (CLBP)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY-3016859. CAS No. 2489584-93-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990071. | |
| Ferene disodium | Ferene disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 79551-14-7. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g. Product ID: HY-D0170. | |
| Ferredoxin-NADP reductase | Ferredoxin-NADP reductase in plants receives electrons from ferredoxin (Fd) at the end of the photosynthetic electron transfer chain and converts NADP+ to NADPH[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9029-33-8. Pack Sizes: 10 U. Product ID: HY-P2944. | |
| Ferric citrate | Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iron(III) citrate; Zerenex. CAS No. 3522-50-7. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 1 g; 10 g. Product ID: HY-N1428C. | |
| Ferric citrate hydrate | Ferric citrate hydrate, an orally active iron supplement, is an efficacious phosphate binder. Ferric citrate hydrate can be used for iron deficiency anemia and chronic kidney disease (CKD) research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2338-5-8. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-47030. | |
| Ferrichrome Iron-free | Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be used as a heterosiderophore by bacteria, including Pseudomonas aeruginosa and Vibrio parahaemolyticus. Ferrichrome (0.8 μM) inhibits concanavalin A-induced proliferation of mouse spleen monocytes and reduces the number of concanavalin A-stimulated CD4+ T cells expressing IL-2 receptor. It also inhibits the heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Desferrichrome; DFC; N-Desferriferrichrome. CAS No. 34787-28-5. Pack Sizes: 1 mg. Product ID: HY-P1997. | |
| Ferric maltol | Ferric maltol is an orally active monovalent iron (Fe3+) complex. Ferric maltol is used in the study of iron deficiency anemia in inflammatory bowel disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 33725-54-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108017. | |
| Ferric nitrilotriacetate | Ferric nitrilotriacetate (Fe-NTA), a complexation of nitriloacetic acid with iron, is a highly reactive compound used to induce degenerative disorders through oxidative stress (OS). Ferric nitrilotriacetate is also used in several studies to induce hyperglycemia, glycosuria, and both renal and liver carcinogenesis[1]. Uses: Scientific research. Category: Induced disease models products. CAS No. 16448-54-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145157. | |
| Ferrocene-d10 | Ferrocene-d10 is the deuterium labeled Ferrocene[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 12082-87-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-79504S. | |
| Ferroheme | Ferroheme is the ferrous form of heme in hemoglobin, reversibly binding oxygen as an oxygen carrier. Its free form induces oxidative stress and ferroptosis by releasing iron ions, which catalyze reactive oxygen species generation via Fenton reactions, leading to lipid peroxidation and cell death. This mechanism is critical in pathological contexts like intracerebral hemorrhage and neurodegenerative diseases, making it a target for studying iron-overload disorders and ferroptosis-related pathologies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14875-96-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111914A. | |
| Ferroptosis-IN-19 | Ferroptosis-IN-19 (compound C18) is a strong cellular ferroptosis inhibitor with an IC50 value of 0.097 μM. Ferroptosis-IN-19 shows high metabolic stability and favorable BBB permeability prediction. Ferroptosis-IN-19 has in vivo neuroprotection against ischemic brain injury in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3025114-13-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173313. | |
| Ferroptosis-IN-22 | Ferroptosis-IN-22 is a selective ferroptosis inhibitor by targeting NCOA4 and disrupting its interaction with ferritin with an EC50 of 520 nM and a Kd of 0.78 μM. Ferroptosis-IN-22 has a strong inhibitory activity against ferroptosis induced by multiple ferroptosis inducers (RSL3 (HY-100218A), Erastin (HY-15763), ML210 (HY-100003), FIN56 (HY-103087)), but does not inhibit necrosis induced by H2O2 or apoptosis induced by STS (HY-15141). Ferroptosis-IN-22 effectively ameliorates Concanavalin A (HY-P2149)-induced acute liver injury. Ferroptosis-IN-22 can be used for the study of ferroptosis-related diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3096878-87-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175869. | |
| Ferroquine | Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ferrochloroquine; SSR97193. CAS No. 185055-67-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19364. | |
| Ferrostatin-1 | Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Ferrostatin-1 exhibits antifungal activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fer-1. CAS No. 347174-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100579. | |
| Ferrous gluconate | Ferrous gluconate is a highly water-soluble iron-containing agent with high bioavailability and bactericidal activity. As a non-heme iron, Ferrous gluconate is used for meat product fortification and improvement of iron deficiency anemia. Ferrous gluconate induces ferroptosis in E. coli through Fe2+ infiltration, reactive oxygen species burst, lipid peroxidation and direct interaction with DNA. Ferrous gluconate also downregulates the SOS responsive transcriptional repressor LexA. In addition, Ferrous gluconate regulates multiple key pathways in E. coli such as fatty acid metabolism, iron-sulfur cluster assembly and pyruvate metabolism, and is applied in studies related to *E. coli* infection and iron deficiency anemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 299-29-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-W698249. | |
| Ferrozine | Ferrozine is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm[1][2]. Ferrozine-based colorimetric assays can quantify iron in cells[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 69898-45-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-137805. | |
| Ferrozine sodium hydrate | Ferrozine sodium hydrate is a spectrophotometric reagent for iron, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm[1][2].Ferrozine sodium hydrate-based colorimetric assays can quantify iron in cells[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1266615-85-3. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-W151629A. | |
| Ferruginol | Ferruginol ((+)-Ferruginol), a natural diterpenoid, is an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). Ferruginol inhibits the growth of thyroid cancer cells through the induction of mitochondrial apoptosis. Ferruginol has antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Ferruginol. CAS No. 514-62-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6033. | |
| Fertirelin | Fertirelin is a GnRH and LH-RH analogue. Fertirelin can be used of the study for reversing cow follicular cysts[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38234-21-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0053. | |
| Ferulenol | Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6805-34-1. Pack Sizes: 5 mg. Product ID: HY-129605. | |
| Ferulic acid | Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Coniferic acid. CAS No. 1135-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g; 5 g. Product ID: HY-N0060. | |
| Ferulic acid 4-O-sulfate | Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ferulic acid 4-sulfate. CAS No. 86321-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147323. | |
| Ferulic acid acyl-β-D-glucoside | Ferulic acid acyl-β-D-glucoside (Ferulic acid glucoside) is a metabolite of Ferulic Acid (HY-N0060). Ferulic acid acyl-β-D-glucoside can be isolated from flaxseed extract. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50 values of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ferulic acid glucoside; Feruloyl glucose ester. CAS No. 7196-71-6. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N7715. | |
| Ferulic acid methyl ester | Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties[1][2]. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders[1]. Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methyl ferulate. CAS No. 2309-7-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W018643. | |
| Feruloyl esterase | Feruloyl esterase plays a major role in the degradation of plant biomass. Feruloyl esterase catalyzes the cleavage and formation of ester bonds between plant cell wall polysaccharide and phenolic acid[1]. Uses: Scientific research. Category: Enzymes. CAS No. 134712-49-5. Pack Sizes: 100 U; 500 U; 1 KU. Product ID: HY-E70115. | |
| Feruloylputrescine | Feruloylputrescine is an oral active phenolamide found in citrus plants and formed through the decarboxylation of L-Arginine. Feruloylputrescine inhibits monooxygenase (cntA) and reductase (cntB) and trimethylamine production. Feruloylputrescine can be used for cardiovascular diseases research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 501-13-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W327449. | |
| Ferumoxytol | Ferumoxytol is an FDA-approved ultrasmall superparamagnetic iron oxide preparation and iron replacement agent that exerts selective activity against leukemia cells with low ferroportin expression. Ferumoxytol increases intracellular iron levels, induces reactive oxygen species (ROS) production via the Fenton reaction, and triggers oxidative stress and cell death. Ferumoxytol reduces disease burden in mouse models and patient-derived leukemia models. As an MRI contrast agent, Ferumoxytol enables imaging of vascular lesions, tumors and lymph nodes. Ferumoxytol can be used in research related to acute myeloid leukemia and blast-phase chronic myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 722492-56-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108894. | |
| Fesoterodine | Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 286930-02-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-70053. | |
| Fesoterodine L-mandelate | Fesoterodine L-mandelate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine L-mandelate is used for the overactive bladder (OAB)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1206695-46-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-70053A. | |
| FeTCPP chloride | FeTCPP chloride (Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride) is a metallic porphyrin compound formed by the coordination of a central iron ion (Fe3+) with four 4-carboxyphenylporphyrins (TCPP). FeTCPP chloride can be used as a catalyst for catalytic, electrochemical, photochemical and biomedical research. FeTCPP chloride has high photocatalytic performance for p-nitrophenol under visible light. FeTCPP chloride also has peroxisase-like activity, which is used in bionic catalysis research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride. CAS No. 55266-17-6. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-W075707. | |
| FeTPPS | FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage[1]. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 90384-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131697. | |
| Fetrastobart | SGN-PDL1V Antibody is a PD-L1 targeting antibody. SGN-PDL1V Antibody can be used for synthesis of ADC SGN-PDL1V (HY-171821)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SGN-PDL1V Antibody; PF-08046054 Antibody. CAS No. 3028439-63-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991506. | |
| Fetuin, Fetal Bovine Serum | Fetuin, Fetal Bovine Serum is a liver-secreted 64 kDa plasma glycoprotein isolated from fetal bovine serum. Fetuin, Fetal Bovine Serum inhibits trypsin activity and promote cellular attachment, growth, and differentiation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9014-81-7. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-P2352. | |
| Fevipiprant | Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: QAW039; NVP-QAW039. CAS No. 872365-14-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16768. | |
| Fexagratinib | Fexagratinib (AZD4547; ADSK091) is a potent inhibitor of the FGFR family with IC50s of 0.2 nM, 2.5 nM, 1.8 nM, and 165 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD4547; ADSK091. CAS No. 1035270-39-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13330. | |
| Fexaramine | Fexaramine is a potent and selective FXR agonist with an EC50 of 25 nM. Fexaramine has no activity against hRXRα, hPPARαγδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ, and hVDR receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 574013-66-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-10912. | |
| Fexinidazole | Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HOE 239. CAS No. 59729-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13801. | |
| Fexlamose | Fexlamose (AER-01) is a thiol-modified carbohydrate agent with mucolytic property. Fexlamose cleaves disulfides to cause mucolysis. Fexlamose can be used for researchs of chronic obstructive pulmonary disease (COPD) and muco-obstructive lung diseases (MOLD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AER-01; MUC-031. CAS No. 1285607-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168973. | |
| Fexofenadine | Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MDL-16455; Terfenadine carboxylate. CAS No. 83799-24-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0801. | |
| Fezagepras sodium | Fezagepras (Setogepram) sodium acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84[1]. Fezagepras sodium decreases renal, liver and pancreatic fibrosis[1][2]. Fezagepras sodium exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Setogepram sodium; PBI-4050 sodium. CAS No. 1254472-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100775. | |
| Fezakinumab | Fezakinumab (ILV 094) is an anti-IL-22 monoclonal antibody. Fezakinumab inhibits IL-22 signal transduction, and regulates the JAK1/STAT3 pathway as well as apoptotic proteins. Fezakinumab alleviates airway remodeling, alveolar enlargement and inflammatory cell infiltration in lung tissues. Fezakinumab reduces the levels of neutrophils, lymphocytes, eosinophils and macrophages in lung tissues. Fezakinumab can be used in the research of chronic obstructive pulmonary disease and skin diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ILV 094. CAS No. 1007106-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99244. | |
| Fezolinetant | Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ESN-364. CAS No. 1629229-37-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19632. | |
| FFN 206 dihydrochloride | FFN 206 dihydrochloride, a fluorescent probe, is used as an excellent Vesicular Monoamine Transporter 2 (VMAT2) substrate with an apparent Km of 1.16 μM. FFN 206 dihydrochloride is capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1883548-88-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-110334. | |
| FFN246 | FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2210244-83-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149170. | |
| FFN511 | FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1004548-96-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103465. | |
| FG-2216 | FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2), with an IC50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IOX3; YM311. CAS No. 223387-75-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15641. | |
| FG-3019 | FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pamrevlumab; Anti-Human CTGF Recombinant Antibody. CAS No. 946415-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99288. | |
| FG 7142 | FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZK 39106; LSU-65. CAS No. 78538-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100991. | |
| FGFR2-IN-2 | FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2677709-81-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145231. | |
| FGFR3-IN-5 | FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2446664-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148779. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.