MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| FITC-Dextran (MW 2000000) | FITC-Dextran (MW 2000000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Uses: Scientific research. Category: Signaling pathways. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-128868I. |  |
| FITC-Dextran (MW 3000-5000) | FITC-Dextran (MW 3000-5000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 3000-5000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 3000-5000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3]. Storage: protect from light. Uses: Scientific research. Category: Signaling pathways. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128868B. | |
| FITC-Dextran (MW 4000) | FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-128868A. | |
| FITC-Dextran (MW 40000) | FITC-Dextran (MW 40000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 40000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 40000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128868D. | |
| FITC-Dextran (MW 500000) | FITC-Dextran (MW 500000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Uses: Scientific research. Category: Signaling pathways. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128868H. | |
| FITC-Dextran (MW 70000) | FITC-Dextran (MW 70000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Uses: Scientific research. Category: Signaling pathways. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128868E. | |
| Fitusiran | Fitusiran (ALN-AT3SC) is a siRNA strategy. Fitusiran delivers siRNA targeting the SERPINC1 gene in hepatocytes to inhibit antithrombin synthesis. Fitusiran enhances thrombin activity and increases Thrombin generation, thereby restoring hemostatic function. Fitusiran can be used in hemophilia-related research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALN-AT3SC; SAR439774. CAS No. 1499251-18-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132587. | |
| FiVe1 | FiVe1 is a vimentin (VIM) inhibitor. FiVe1 binds to the rod domain of VIM, causing metaphase VIM disassembly and hyperphosphorylation at Ser56, ultimately leading to mitotic catastrophe, multinucleation, and loss of stemness. FiVe1 has anticancer activity against soft tissue sarcomas. FiVe1 increases the sensitivity of ovarian cancer to Cisplatin (HY-17394). FiVe1 can be used for researches of mesenchymal cancers (including breast cancer and soft tissue sarcoma) and ovarian cancers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 932359-76-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124757. | |
| FIZ1 degrader 1 | FIZ1 degrader 1 (compound 1) is an IMiD-based molecular glue degrader targeting FIZ1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1957235-62-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169343. | |
| Fiztasovimab | Fiztasovimab (NPC-21; EV2038) is a fully human IgG1λ mAb against human cytomegalovirus (hCMV). Fiztasovimab acts neutralizing activity by binding to the antigenic domain 1 of glycoprotein B on hCMV envelope. Fiztasovimab inhibits cell-to-cell transmission of hCMV[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NPC-21; EV2038. CAS No. 2467411-25-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99621. | |
| FK-565 | FK-565 is a nucleotide oligomerization domain-1 (NOD1) ligand. FK-565 induces murine model with arteritis[1]. Uses: Scientific research. Category: Induced disease models products. CAS No. 79335-75-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W746708. | |
| FKB04 | FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanism in liver cancer cells, leading to T-loop defects, telomere shortening, and cellular senescence. Additionally, FKB04 can inhibit tumor growth in a human liver cancer xenograft mouse model (with Huh-7 cells implanted in BALB/c mice). FKB04 can be used in liver cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 108979-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169120. | |
| FKBP12 PROTAC dTAG-13 | FKBP12 PROTAC dTAG-13 (dTAG-13), a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 effectively engages FKBP12F36V and CRBN, thereby selectively degrading FKBP12F36V[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: dTAG-13. CAS No. 2064175-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-114421. | |
| FKBP12 PROTAC dTAG-7 | FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional PROTAC degrader. FKBP12 PROTAC dTAG-7 targets FKBP12F36V and BET BRD4. FKBP12 PROTAC dTAG-7 enables rapid and selective degradation of target proteins, and is suitable for cellular and in vivo studies to analyze protein functions and validate targets[1]. (Pink: target protein ligand (HY-114420); Black: linker (HY-128844); Blue: CRBN Ligand (HY-103597); CRBN Ligand+linker: (HY-W722323)). Uses: Scientific research. Category: Signaling pathways. Alternative Names: dTAG-7. CAS No. 2064175-32-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123941. | |
| FKBP12 PROTAC RC32 | FKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader based on PROTAC technology. FKBP12 PROTAC RC32 contains conjugation of Rapamycin (HY-10219) and a ligand for an Cereblon E3 ubiquitin ligase (Pomalidomide; HY-10984)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC32. CAS No. 2375555-66-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130835. | |
| FKGK18 | FKGK18 is a selective group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor. FKGK18 is a fluoroketone (FK)-based compound with IC50s of 50 nM and 3 μM for iPLA2β and iPLA2γ. FKGK18 can be used for the research of beta-cell apoptosis and diabetes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1071001-09-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-115403. | |
| FKK6 | FKK6 is a selective agonist for pregnane X receptor (PXR) with an EC50 of 1.2 μM. FKK6 exhibits good affinity with plasma proteins, and good metabolic metabolism in human microsomes. FKK6 inhibits PXR-related NF-κB signaling pathway, inhibits the expression of inflammatory factors, and exhibits anti-inflammatory activity against DSS (HY-116282)-induced colitis in mouse model[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2238839-34-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-168328. | |
| FL118 | FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 10,11-(Methylenedioxy)-20(S)-camptothecin. CAS No. 135415-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12486. | |
| FL118-14-Propanol | FL118-14-Propanol is a FL118 derivative. FL118-14-Propanol synthesized ADC molecule has good anti-tumor effect in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2821768-98-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156856. | |
| Flagelin 22 | Flagelin 22 (Flagellin 22), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Flagellin 22. CAS No. 304642-91-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1568. | |
| FLAG peptide | FLAG peptide is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide maintances the natural folding of its fusing proteins. FLAG peptide can be removed by enterokinase, and eluted under non-denaturing conditions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 98849-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0223. | |
| Flanvotumab | Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMC-20D7S. CAS No. 1188277-05-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99622. | |
| FlAsH-EDT2 | FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 binds to Cys4 with high affinity and emits fluorescence. FlAsH-EDT2 can cross the cell membrane and enter the interior of the cell. FlAsH-EDT2 can only be used for labeling proteins with high concentration[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 212118-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130412. | |
| Flavagline FL3 | Flavagline FL3 is a flavagline with potent and selective cytotoxicity in cancer cells.Flavagline FL3 induces apoptosis of HL60 and Hela cells by triggering the translocation of Apoptosis Inducing Factor (AIF) and caspase-12 to the nucleus[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1186012-80-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123554. | |
| Flavin adenine dinucleotide | Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAD. CAS No. 146-14-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1654. | |
| Flavin adenine dinucleotide disodium salt | Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAD disodium salt; FAD-Na2. CAS No. 84366-81-4. Pack Sizes: 10 mM * 1 mL in Water; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B1654A. | |
| Flavin adenine dinucleotide (Standard) | Flavin adenine dinucleotide (Standard) is the analytical standard of Flavin adenine dinucleotide. This product is intended for research and analytical applications. Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAD (Standard). CAS No. 146-14-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1654R. | |
| Flavokawain B | Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8, cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-κB, PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation[1][2][3][4][5][6][7][8][9][10][11][12][13]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Flavokavain B. CAS No. 1775-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2132. | |
| Flavokawain C | Flavokawain C is an orally active natural chalcone. Flavokawain C inhibits the proliferation of various cancer cells. Flavokawain C upregulates GADD153 in cancer cells, inhibits the phosphorylation of Akt and JNK, suppresses early ERK phosphorylation, activates late ERK phosphorylation, activates caspase related subtypes, induces PARP-1 cleavage, causes upregulation of p21 and p27, downregulation of mutant p53 and anti-apoptotic IAP proteins, elevates intracellular ROS levels, reduces SOD activity, and induces apoptosis. Flavokawain C downregulates FABP4, induces autophagy in cancer cells, and activates the AMPK/mTOR pathway. Flavokawain C decreases the expression of glycolysis-related proteins GLUT1 and HK2, and inhibits glycolysis in nasopharyngeal carcinoma cells. Flavokawain C inhibits the activation of the EGFR/PI3K/Akt/mTOR signaling pathway and reduces the expression of HSP90B1. Flavokawain C inhibits angiogenesis by decreasing the expression of angiogenic proteins Ang-1 and VEGF in human umbilical vein endothelial cells. Flavokawain C increases γ-H2AX levels in cells, inhibits the phosphorylation of FAK, PI3K and AKT in cells, and induces DNA damage in cells. Flavokawain C exerts anti-tumor activity in multiple tumor xenograft mouse models. Flavokawain C is applicable to research related to colorectal cancer, colon adenocarcinoma, nephroblastoma, nasopharyngeal carcinoma and liver cancer[1][2][3][4][5][6][7]. | |
| Flavokermesic acid | Flavokermesic acid is an anthraquinone dye that can be detected in extracts of insects from the family Diaspididae, and it is a minor pigment component thereof. Flavokermesic acid can be used to investigate the biosynthetic pathways of insect-derived anthraquinone pigments[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18499-84-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N15351. | |
| Flavonol | Flavonol is a cholinesterase (ChE) inhibitor, with an IC50 value of 120 μM and a Ki value of 74 μM. Flavonol has antioxidant, free radical-scavenging, antibacterial properties, and immune modulation functions. Flavonol inhibits the PriA helicase of Staphylococcus aureus. Flavonol can suppress the production of NO in LPS-activated RAW 264.7 cells by inhibiting the expression of the iNOS enzyme. Flavonol shows protective and analgesic effects in mice through various neuronal pathways. Flavonol can be used in research related to tumors and atherosclerosis diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 577-85-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-107825. | |
| Flavopiridol | Flavopiridol (Alvocidib) is a broad spectrum and competitive inhibitor of CDKs, inhibiting CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMR-1275; Alvocidib; L86-8275. CAS No. 146426-40-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-10005. | |
| Flavopiridol Hydrochloride | Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK, competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Alvocidib Hydrochloride; L86-8275 Hydrochloride; HMR-1275 Hydrochloride. CAS No. 131740-09-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10006. | |
| Fl-DIBO | Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference[1][2]. Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1407523-31-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1506. | |
| Flecainide | Flecainide is an orally active antiarrhythmic agent. Flecainide can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2). Flecainide can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 54143-55-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W010950. | |
| Flecainide acetate | Flecainide acetate (R-818) is a class 1C antiarrhythmic agent especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R-818. CAS No. 54143-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17429. | |
| Flesinoxan | Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan also has effective anxiolytic/antidepressant effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 98206-10-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121653. | |
| Flezurafenibum | Flezurafenibum (Flezurafenib) is a rapidly accelerated fibrosarcoma (Raf) kinase inhibitor, with antineoplastic effect[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Flezurafenib. CAS No. 2760321-00-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159534. | |
| FLI-06 | FLI-06 is an inhibitor of Notch signaling with an EC50 of 2.3 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 313967-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15860. | |
| Flibanserin | Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research[1]-[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIMT-17; BIMT-17BS. CAS No. 167933-07-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0095. | |
| Flindersine | Flindersine is an alkaloid with multiple activities including antibacterial, antifungal, antitumor, and antidiabetic properties. Flindersine increases the activity of antioxidant enzymes, restores the levels of renal biomarkers, and reduces blood glucose, blood lipid, and insulin levels in diabetic rats. Flindersine inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, drug-resistant bacteria, as well as dermatophytes, filamentous fungi, and yeasts. Flindersine reduces the viability of cancer cells and induces apoptosis. Flindersine can be used in research related to breast cancer, type 2 diabetes, bacterial infections, and fungal infections[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 523-64-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W984782. | |
| Flindokalner | Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-204352. CAS No. 187523-35-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108584. | |
| Flizasertib | Flizasertib (GDC-8264) is an orally active, reversible and selective RIP1 inhibitor with Kiapp values of 0.00071 μM and 0.0013 μM for human and cynomolgus monkey RIP1 kinase, respectively. Flizasertib blocks RIP1 autophosphorylation but does not affect RIP1 protein stability. Flizasertib inhibits pro-inflammatory cytokines (CCL3, CCL4, and IL-1β) production. Flizasertib results in inhibition of colitis and ileitis. Flizasertib can be used in the research of cardiac surgery-associated acute kidney injury[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-8264. CAS No. 2268739-68-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-152846. | |
| Flocoumafen | Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WL 108366. CAS No. 90035-08-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-111186. | |
| Floctafenine | Floctafenine, a nonsteroidal anti-inflammatory agent (NSAID), acts as an effective analgesic agent[1][2]. Floctafenine is an inhibitor of COX-1 and COX-2 activities in vitro,showing a slightly higher potency towards COX-I. Floctafenine is used for the research of short term pain research[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23779-99-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-A0259. | |
| Flomoxef sodium | Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92823-03-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0706A. | |
| Flonicamid | Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IKI220. CAS No. 158062-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-119649. | |
| Flonoltinib | Flonoltinib is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. Flonoltinib has anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JAK2/FLT3-IN-1. CAS No. 2387765-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-130247. | |
| Florbetapir | Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AV-45; Flobetapir. CAS No. 938435-69-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129650. | |
| Florfenicol | Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions[6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Florfenicol; SCH-25298. CAS No. 73231-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B1374. | |
| Florfenicol-d3 | Florfenicol-d3 ((-)-Florfenicol-d3)?is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Florfenicol-d3; SCH-25298-d3. CAS No. 2213400-85-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B1374S1. | |
| Florfenicol (Standard) | Florfenicol (Standard) is the analytical standard of Florfenicol. This product is intended for research and analytical applications. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions[6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Florfenicol (Standard); SCH-25298 (Standard). CAS No. 73231-34-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1374R. | |
| Flotetuzumab | Flotetuzumab (MGD006; S80880) is an investigational CD123/CD3 bispecific dual-affinity retargeting antibody (DART) molecule.Flotetuzumab reactivates T cells by simultaneously binding to CD123 in target cells and CD3 in effector T cells, leading to T-cell-mediated cytotoxicity in target cells. Flotetuzumab shows inhibitory effect on a mouse model of patient-derived xenograft (PDX) in acute myeloid leukemia (AML)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MGD006; S80880. CAS No. 1664355-28-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99623. | |
| Floxuridine | Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis[1][2]. Floxuridine has antiviral effects against HSV and CMV[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Fluorouracil 2'-deoxyriboside. CAS No. 50-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-B0097. | |
| FLTX1 | FLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1481401-71-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119437. | |
| Fluazinam | Fluazinam is an orally active dinitroaniline fungicide. Fluazinam induces phosphorylation of JNK, activates p38 pathway, decreases Bcl-2, activates caspase-3, decreases complex I activity, increases Autophagy and Apoptosis. Fluazinam has strong antifungal activity against F. fujikuroi and B. maydis. Fluazinam has a negative impact on Brachydanio rerio and worker bees[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 79622-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B1839. | |
| Flubendiamide | Flubendiamide (NNI-0001) is an orally active phthalic diamide insecticide that acts by targeting insect ryanodine receptors (RyRs), causing insect muscle dysfunction, paralysis and death. Flubendiamide disrupts molting, metamorphosis and reproductive processes, induces oxidative stress by increasing the levels of ROS/RNS, MDA and 8OHdG and decreasing the levels of SOD, CAT and GST, activates the CncC/Maf apoptosis pathway, impairs calcium homeostasis, promotes adipogenesis, increases triglyceride accumulation, and upregulates the expression of regulatory factors for adipocyte differentiation and adipogenesis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NNI-0001. CAS No. 272451-65-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W339331. | |
| Fluc-IN-1 | Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2940242-10-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170496. | |
| Flucloxacillin sodium | Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1847-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0246A. | |
| Fluconazole | Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UK-49858. CAS No. 86386-73-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0101. | |
| Fluconazole-d4 | Fluconazole-d4 is the deuterium labeled Fluconazole. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UK-49858-d4. CAS No. 1124197-58-5. Pack Sizes: 1 mg. Product ID: HY-B0101S. | |
| Flucytosine | Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Fluorocytosine; NSC 103805; Ro 2-9915. CAS No. 2022-85-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0139. | |
| Fludarabine | Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: F-ara-A; NSC 118218. CAS No. 21679-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0069. | |
| Fludarabine-Cl | Fludarabine-Cl has an inhibitory effect on RNA adenosine deaminase 1 (ADAR1) with an IC50 of 0.87 μM and can be used to prevent and/or study cancer or tumor-related diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2734853-80-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145443. | |
| Fludarabine phosphate | Fludarabine (phosphate) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 118218 phosphate. CAS No. 75607-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0028. | |
| Fludioxonil | Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGA-173506. CAS No. 131341-86-1. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-W021040. | |
| Fludrocortisone | Fludrocortisone (9α-Fludrocortisone) is an orally active mineralocorticoid and glucocorticoid receptor agonist. Fludrocortisone suppresses pro-inflammatory cytokine expression, reduces CCL2, IL-6, IL-8 levels, upregulates mineralocorticoid receptor (MR) expression, induces PI3K/Akt, GSK-3β, CREB, ERK1/2, mTOR phosphorylation, blocks Tau hyperphosphorylation, prevents apoptosis, promotes survival and proliferation, enhances renal sodium and water transport, increases plasma volume and blood pressure, reduces plasma potassium and renin activity, stimulates erythropoietin expression, modulates uterine receptivity genes, and reverses PP242-induced MUC1 upregulation. Fludrocortisone can be used for the research of congenital adrenal hyperplasia, postural hypotension, and adrenal insufficiency[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9α-Fludrocortisone; 9α-Fluorcortisol. CAS No. 127-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1203. | |
| Fludrocortisone acetate | Fludrocortisone acetate (9α-Fludrocortisone acetate) is an orally active synthetic mineralocorticoid. Fludrocortisone acetate can effectively control sodium retention. Fludrocortisone acetate is used in studies of cardiac injury, adrenal insufficiency and orthostatic hypotension[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9α-Fludrocortisone acetate; 9α-Fluorcortisol acetate. CAS No. 514-36-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B1203A. | |
| Flufenamic acid | Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation. Uses: Scientific research. Category: Signaling pathways. CAS No. 530-78-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1221. | |
| Flufenamic acid-13C6 | Flufenamic acid-13C6 is the 13C6 labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation. Uses: Scientific research. Category: Signaling pathways. CAS No. 1325559-30-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B1221S1. | |
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