MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Foscenvivint | PRI-724 is a selective inhibitor of the CBP/β-catenin interaction. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRI-724. CAS No. 1422253-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112045. |  |
| Fosfenopril | Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fosinoprilat; Fosinoprilic acid; SQ 27519. CAS No. 95399-71-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-107352. | |
| Fosfluconazole | Fosfluconazole is a proagent of Fluconazole that is widely used as an antifungal agent. Uses: Scientific research. Category: Signaling pathways. CAS No. 194798-83-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100666. | |
| Fosfomycin calcium | Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0955 calcium. CAS No. 26016-98-8. Pack Sizes: 100 mg. Product ID: HY-B1075. | |
| Fosfomycin sodium | Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0955 sodium. CAS No. 26016-99-9. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W016420. | |
| Fosfructose | Fosfructose is an orally active cyclooxygenase-2 inhibitor and Toll-like receptor 4 modulator. Fosfructose reduces the expression of cyclooxygenase-2, thereby decreasing prostaglandin production. By inhibiting the Toll-like receptor 4 signaling pathway, Fosfructose downregulates LPS-induced adhesion molecule expression. Fosfructose is applicable to research related to ischemic stroke, epilepsy, sepsis, myocardial injury, osteoporosis, and ultraviolet B-induced skin damage[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diphosphofructose; Esafosfan; FDP. CAS No. 488-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106950. | |
| Fosgonimeton | Fosgonimeton (ATH-1017) is a hepatocyte growth factor receptor (c-Met/HGFR) agonist. Fosgonimeton has neuroprotective effects in both LPS (HY-D1056) -induced neuroinflammation and Aβ-induced AD models[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATH-1017. CAS No. 2093305-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132814. | |
| Fosifloxuridine nafalbenamide | Fosifloxuridine nafalbenamide (NUC-3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. Fosifloxuridine nafalbenamide has anticancer activity. Fosifloxuridine nafalbenamide has the potential to evoke a host immune response and enhance immunoresearch[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NUC-3373. CAS No. 1332837-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109115. | |
| Fosmanogepix | Fosmanogepix (APX001) is a broad-spectrum agent against invasive fungal infections. Fosmanogepix (APX001) targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. This inhibition prevents the appropriate localization of cell wall mannoproteins, which compromises cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix (APX001) can be used for invasive fungal infections research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APX001; E1211. CAS No. 2091769-17-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119726. | |
| Fosmetpantotenate | Fosmetpantotenate is a phosphopantothenic acid (PPA) precursor designed to release PPA intracellularly, leading to restoration of CoA levels. Fosmetpantotenate is used to research pantothenate kinase-associated neurodegeneration. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RE-024. CAS No. 1858268-66-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109033. | |
| Fosmidomycin sodium salt | Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FR-31564. CAS No. 66508-37-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112853. | |
| Fosphenytoin disodium | Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials. Uses: Scientific research. Category: Signaling pathways. CAS No. 92134-98-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1657A. | |
| Fosribnicotinamide | Fosribnicotinamide (β-nicotinamide mononucleotide) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of Fosribnicotinamide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-Nicotinamide mononucleotide; β-NM; NMN. CAS No. 1094-61-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-F0004. | |
| Fosribnicotinamide (Standard) | Fosribnicotinamide (Standard) (β-Nicotinamide mononucleotide (Standard)) is the analytical standard of Fosribnicotinamide (HY-F0004). This product is intended for research and analytical applications. Fosribnicotinamide is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of Fosribnicotinamide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-Nicotinamide mononucleotide (Standard); β-NM (Standard); NMN (Standard). CAS No. 1094-61-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-F0004R. | |
| Fostamatinib | Fostamatinib (R788) is the oral proagent of the active compound R406[1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R788. CAS No. 901119-35-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13038A. | |
| Fostamatinib Disodium | Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406[1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R788Disodium. CAS No. 1025687-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13038. | |
| Fostamatinib disodium hexahydrate | Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406[1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R788 disodium hexahydrate. CAS No. 914295-16-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13038B. | |
| Fostemsavir | Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-663068. CAS No. 864953-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15440A. | |
| Fosthiazate | Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 98886-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W020785. | |
| FOXM1-IN-1 | FOXM1-IN-1 is a potent FOXM1 inhibitor with an IC50 value of 2.65 μM. FOXM1-IN-1 shows antiproliferative activity. FOXM1-IN-1 decreases the the expression of FOXM1, PLK1, CDC25B protein[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2864407-22-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151986. | |
| FOXO1-IN-3 | FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2451093-95-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153617. | |
| FOXO4-DRI | FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI is a senolytic peptide that induces apoptosis of senescent cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2460055-10-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4157. | |
| Foxy-5 | Foxy-5, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 881188-51-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1416. | |
| FOY 251 | FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor[1][2]. FOY 251 inhibits SARS-CoV-2 infection in cells assay[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71079-09-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19727A. | |
| FPA-124 | FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC50 of 0.1 μM. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902779-59-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15369. | |
| FP-Biotin | FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 259270-28-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136924. | |
| FPFT-2216 | FPFT-2216, a molecular glue compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1α (CK1α). FPFT-2216 can be used for the research of cancer and inflammatory disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2367619-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145319. | |
| FPH1 | FPH1(BRD-6125) increases the number and activity of primary human hepatocytes in vitro and promotes the differentiation of iPS cells towards a hepatic lineage[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BRD6125. CAS No. 708219-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-100590. | |
| FPL64176 | FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca2+ channels with an EC50 value of 16 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 120934-96-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103307. | |
| FPR1 antagonist 1 | FPR1 antagonist 1 (compound 24a) is a formyl peptide receptor 1 (FPR1) antagonist with an IC50 of 25 nM. FPR1 antagonist 1 inhibits cell growth through a combined effect on cell proliferation and apoptosis and reduces cell migration, while inducing an increase in angiogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053980-28-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156293. | |
| FPR1 antagonist 3 | FPR1 antagonist 3 (compound 10) is a potent and selective FPR1 antagonist. FPR1 antagonist 3 inhibits superoxide anion generation and elastase release with IC50s of 0.33 and 0.84 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3058943-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176403. | |
| FPR2 agonist 3 | FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS (HY-D1056) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6. FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2829263-19-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155335. | |
| FPR Agonist 43 | FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 903895-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19574. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity and BBB-permeable RAGE inhibitor with a Ki of 25 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 945714-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19370. | |
| FR054 | FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 35954-65-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124909A. | |
| FR 180204 | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC50s of 0.51 μM (Ki=0.31 μM) and 0.33 μM (Ki=0.14 μM), respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 865362-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12275. | |
| FR194738 | FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 204067-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100303A. | |
| FR194921 | FR194921 is a potent, selective and orally active and cross the blood-brain barrier Adenosine A1 antagonist with Ki value of 6.6, 5400 nM for A1, A2A, respectively. FR194921 shows cognitive-enhancing and anxiolytic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 202646-80-8. Pack Sizes: 5 mg. Product ID: HY-116800. | |
| FR900359 | FR900359 is a depsipeptide selective inhibitor of Gαq/11/14 in mammalia, can inhibits ERK pathway. FR900359 suppresses the proliferation of melanoma cells and decreases of blood pressure. FR900359 also protected against airway hyperreactivity in murine models of allergen sensitization in Ovalbumin, low endotoxin (HY-W250978A)-induced sensitization model of asthma. FR900359 can be used for cancer and cardiovascular disease research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 107530-18-7. Pack Sizes: 250 μg; 500 μg. Product ID: HY-117037. | |
| FR901464 | FR901464 is a potent spliceosome inhibitor with prominent anti-tumor and anti-cancer effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 146478-72-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16212. | |
| Framycetin | Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5"-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Neomycin B; Fradiomycin B. CAS No. 119-04-0. Pack Sizes: 25 mg (16.27 mM * 2.5 mL in 0.9% NaCl); 50 mg (16.27 mM * 5 mL in 0.9% NaCl); 100 mg (16.27 mM * 10 mL in 0.9% NaCl). Product ID: HY-17624. | |
| FRAX1036 | FRAX1036 is a PAK inhibitor with Kis of 23.3 nM, 72.4 nM, and 2.4 μM for PAK1, PAK2 and PAK4, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1432908-05-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19538. | |
| FRAX486 | FRAX486 is a p21-activated kinase (PAK) inhibitor with IC50s of 14, 33 and 39 nM for PAK1, PAK2 and PAK3, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1232030-35-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15542B. | |
| Fraxetin | Fraxetin is isolated from Fraxinus rhynchophylla Hance and has oral bioactivity. Fraxetin has anti-tumor, antibacterial, antioxidant, and anti-inflammatory effects. Fraxetin can induce cell apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 574-84-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-N0580. | |
| Fremanezumab | Fremanezumab (TEV-48125) is a humanized lgG2 monoclonal antibody that selectively and potently binds to calcitonin gene related peptide (CGRp) (IC50 values = 7.943 nM). Fremanezumab binds to mouse CGRP with an IC50 value of 19.6 nM. Fremanezumab counteracts anti-inflammatory effects of CGRP in vitro, including CGRP-mediated inhibition of LPS (HY-D1056)-induced microglial activation. Fremanezumab selectively inhibits the activation of Aδ meningeal nociceptors by cortical spreading depression (CSD) in rats. Fremanezumab can be used for the study of inflammation and chronic migraine[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TEV-48125; LBR-101; PF-04427429; RN-307. CAS No. 1655501-53-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99019. | |
| Frenlosirsen | Frenlosirsen is an antisense oligonucleotide targeted to IRF4. It is used for study of relapsed/refractory multiple myeloma (RRMM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: ION-935918; ION251. CAS No. 2304711-81-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-177632. | |
| Frenlosirsen sodium | Frenlosirsen sodium is an antisense oligonucleotide targeted to IRF4. It is used for study of relapsed/refractory multiple myeloma (RRMM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: ION-935918 sodium; ION251 sodium. CAS No. 2304711-82-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-177632A. | |
| Fresolimumab | Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab improves Bleomycin (HY-108345)-induced acute lung injury. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GC1008. CAS No. 948564-73-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99020. | |
| Frexalimab | Frexalimab (SAR441344) is a second-generation monoclonal antibody targeting the CD40 ligand (CD40L) with a good safety profile. Frexalimab inhibits the binding between CD40 and CD40L to modulate immune response. Frexalimab is likely to help prevent the process of β-cell destruction. Frexalimab is proming for multiple sclerosis, lupus erythematosus, Sj grens syndrome and type I diabetes research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR441344; INX-021. CAS No. 2515463-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99625. | |
| Friedelin | Friedelin is derived from the leaves of Maytenus ilicifolia (Mart). Friedelin is an orally active non-competitive inhibitor of CYP3A4, with IC50 and Ki values of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1, with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively. Friedelin can be used in research related to inflammation, neurological diseases, and metabolic disorders[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 559-74-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N4110. | |
| FRM-024 | FRM-024 is a central nervous system-penetrant, orally active γ-secretase modulator and Aβ42 lowering agent. FRM-024 is used for the research of familial Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2085780-87-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115726. | |
| Frovatriptan succinate hydrate | Frovatriptan succinate hydrate ((R)-Frovatriptan succinate hydrate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate hydrate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate hydrate has the potential for migraine research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Frovatriptan succinate hydrate; SB 209509 succinate hydrate; VML 251 succinate hydrate. CAS No. 158930-17-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-B1658A. | |
| Frovocimab | Frovocimab (LY 3015014) is a humanized IgG4 monoclonal antibody (mAb) that neutralizes PCSK9. Frovocimab inhibits PCSK9 binding to LDL receptor (LDLR) while permitting the normal proteolytic cleavage of the bound intact PCSK9[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 3015014. CAS No. 1643672-70-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99626. | |
| Fructooligosaccharides | Fructooligosaccharides (Oligolevulose) are a class of orally active dietary fibers and prebiotics. Fructooligosaccharides exist in foods such as breast milk, wheat, honey, onions, garlic and bananas. Fructooligosaccharides resist hydrolysis by the body's digestive enzymes and stimulate the growth of beneficial intestinal bacteria through colonic fermentation. Fructooligosaccharides significantly prevent bone loss in the femur and lumbar spine[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oligolevulose. CAS No. 308066-66-2. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-107863. | |
| Fructose | Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. Uses: Scientific research. Category: Induced disease models products. Alternative Names: beta-D-Fructopyranose. CAS No. 7660-25-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 50 g; 100 g. Product ID: HY-N0395. | |
| Fructose 5-dehydrogenase (acceptor) | Fructose 5-dehydrogenase (acceptor) (D-Fructose dehydrogenase) is a membrane-bound flavohemo-protein that catalyzes the oxidation of d-fructose to 5-keto-d-fructose. Fructose 5-dehydrogenase (acceptor) consists of three subunits: subunit I (67 kDa), subunit II (51 kDa), and subunit III (20 kDa)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Fructose dehydrogenase. CAS No. 37250-85-4. Pack Sizes: 50 U; 100 U. Product ID: HY-P2956. | |
| Fructose (Standard) | Fructose (Standard) is the analytical standard of Fructose. This product is intended for research and analytical applications. Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. Uses: Scientific research. Category: Signaling pathways. Alternative Names: beta-D-Fructopyranose (Standard). CAS No. 7660-25-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0395R. | |
| Fructosyl-lysine | Fructosyl-lysine (Fructoselysine) is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine is the precursor to glucosepane, a lysine-arginine protein cross-link that can be an indicator in diabetes?detection[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fructoselysine. CAS No. 21291-40-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129380. | |
| Fructosylvaline | Fructosylvaline (Fructose Valine) is a model fructosyl-amine (Amadori compound) for glycated hemoglobin. Fructosylvaline can be used as a nitrogen source to cultivate microbial strains[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10003-64-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114516. | |
| Frunexian | Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to factor XIa. Frunexian exhibits antithrombotic activity, with no bleeding liability in rat mesenteric arterial puncture model. Frunexian can be used in extracorporeal membrane oxygenation (ECMO) research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EP-7041. CAS No. 1803270-60-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156613. | |
| Fruquintinib | Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0.35, and 35 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMPL-013. CAS No. 1194506-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19912. | |
| Frutinone A | Frutinone A is a CYP1A2 inhibitor, possesses a chromonocoumarin structural scaffold. Frutinone A shows various biological activities, including antibacterial and antioxidant[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38210-27-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W777979. | |
| FSBA hydrochloride | FSBA (5'-p-Fluorosulfonylbenzoyladenosine) hydrochloride is a covalent modifier and affinity labeling reagent for adenine nucleotide-binding proteins. FSBA hydrochloride covalently attaches to the nucleotide-binding sites of pyruvate kinase, glutamate dehydrogenase, and p56lck, and to a lysine residue in the ATP-binding site of cAMP-dependent protein kinase, causing loss of enzymatic activity. FSBA hydrochloride can be used for the research of T lymphoma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5'-p-Fluorosulfonylbenzoyladenosine. CAS No. 78859-42-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123650. | |
| FSEN1 | FSEN1 is a potent and non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 triggers iron death in cancer cells by inhibiting FSP1. FSEN1 can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862808-01-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153629. | |
| FSG67 | FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1158383-34-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112489. | |
| FSHR agonist 1 | FSHR agonist 1 is a high affinity and allosteric follicle stimulating hormone receptor (FSHR) agonist with a pEC50 of 7.72. FSHR agonist 1 formes extensive interactions with the TMD to directly activate FSHR[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1256776-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150210. | |
| FSH receptor antagonist 1 | FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor. FSH receptor antagonist 1 exhibits an IC50 of 28 nM on a cell line expressing the human FSH receptor. FSH receptor antagonist 1 significantly inhibits follicle growth and ovulation in an ex vivo mouse model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 487064-35-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149105. | |
| Fsh receptor-binding inhibitor fragment(bi-10) | FSH receptor-binding inhibitor fragment(bi-10) is a potent FSH antagonist. FSH receptor-binding inhibitor fragment(bi-10) blocks the binding of FSH to FSHR, and alteres FSH action at the receptor level. FSH receptor-binding inhibitor fragment(bi-10) results in the suppression of ovulation and causes follicular atresia of mice. FSH receptor-binding inhibitor fragment(bi-10) has the potential for utilizing to restrain the carcinogenesis of ovarian cancer by down-regulating overexpression of FSHR and ERβ in the ovaries[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 163973-98-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4190. | |
| FSI-TN42 | FSI-TN42 (N42) is a selective, orally active and irreversible ALDH1A1 inhibitor with an IC50 of 23 nM. FSI-TN42 shows 800-fold more potent against ALDH1A1 than ALDH1A2 (IC50 | |
| FSK hydrochloride | FSK hydrochloride is fluorosulfonyloxybenzoyl-L-lysine, which features a long, flexible aryl fluorosulfate-containing side chain that can reach protein sites inaccessible to covalent conjugation. FSK hydrochloride modifies nanomolecules to target epidermal growth factor receptor (EGFR), resulting in irreversibly bound covalent interactions. Through genetically encoded chemical crosslinking, FSK hydrochloride captures unknown enzyme-substrate interactions in living cells, targets residues other than Cys, and mediates crosslinking at the binding periphery. FSK hydrochloride enables the construction of a bioreactive SuFEx system for generating covalent bonds in various proteins both in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033987-42-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-48999A. | |
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