MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Exlinkibart | Exlinkibart (LVGN-6051) targets TNFRSF9 and is an IgG1κ antibody humanized through complementarity-determining region (CDR) grafting technology. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LVGN-6051. CAS No. 2642171-64-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990040. |  |
| Exo1 | Exo1 is a chemical inhibitor of the exocytic pathway. Uses: Scientific research. Group: Signaling pathways. CAS No. 75541-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112670. | |
| Exo2 | Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304684-77-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137975. | |
| exo-BCN-NHS carbonate | exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1493802-77-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W096149. | |
| Exoenzyme C3, clostridium botulinum | Exoenzyme C3, clostridium botulinum is a promising agent to inactivate RhoA in neurons due to preventing the detrimental effect of active Rho in the recovery of injured neuronal systems. Exoenzyme C3, clostridium botulinum is used for the study of post-traumatic neuro-regeneration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 58319-92-9. Pack Sizes: 25 μg. Product ID: HY-P2325. | |
| EZ-482 | EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 ?M for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimers diseas[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1016456-76-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103076. | |
| (E/Z)-4-Hydroxytamoxifen | (E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is a selective estrogen receptor modulator with mixed estrogenic and antiestrogenic activity, which is also an active metabolite of Tamoxifen (HY-13757A). (E/Z)-4-Hydroxytamoxifen is an agonist of the G protein-coupled estrogen receptor ( GPER ) with relatively low affinity (100-1000 nM). (E/Z)-4-Hydroxytamoxifen is promising for research of cyclical mastalgia, such as breast pain, tenderness, and nodularity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Afimoxifene; 4-OHT. CAS No. 68392-35-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16950A. | |
| Ezabenlimab | Ezabenlimab (BI-754091) is an anti- PD-1 mAb with binding constant K d value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BI-754091. CAS No. 2249882-54-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99610. | |
| Ezatiostat | Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: TER199(free base); TLK199. CAS No. 168682-53-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13634A. | |
| Ezetimibe | Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 58235. CAS No. 163222-33-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17376. | |
| Ezetimibe-d4 | Ezetimibe-d 4 is the deuterium labeled Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SCH 58235-d4. CAS No. 1093659-90-5. Pack Sizes: 1 mg. Product ID: HY-17376S. | |
| Ezetimibe ketone | Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EZM-K. CAS No. 191330-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133114. | |
| Ezetimibe phenoxy glucuronide | Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity [1]. Ezetimibe is a potent cholesterol absorption inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide. CAS No. 190448-57-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-135391. | |
| (E/Z)-GO289 | (E/Z)-GO289 is a potent and selective casein kinase 2 (CK2) inhibitor (IC50=7 nM). (E/Z)-GO289 strongly lengthens circadian period. (E/Z)-GO289 exhibits cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 694522-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115519. | |
| EZH2-IN-14 | EZH2-IN-14 is a selective EZH2 ( Histone Methyltransferase ) inhibitor with an IC 50 of 12 nM. EZH2-IN-14 inhibits the methyltransferase activity of EZH2/PRC2 (that is, reducing H3K27me3). EZH2-IN-14 shows >200-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1979157-17-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148458. | |
| EZM0414 | EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay). EZM0414 can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2411748-50-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144858. | |
| EZM0414 TFA | EZM0414 (SETD2-IN-1) TFA is the TFA salt form of EZM0414 (HY-144858). EZM0414 TFA is a potent, selective, orally active inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay). EZM0414 TFA can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SETD2-IN-1 TFA. CAS No. 2411759-92-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136328. | |
| EZM 2302 | EZM 2302 is a potent and orally active CARM1 inhibitor with an IC50 value of 6 nM. EZM 2302 shows antiproliferative activity and anti-tumor activity. EZM 2302 inhibits PABP1 and SMB expression[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1628830-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111109. | |
| (E/Z)-N-Desethylsunitinib hydrochloride | (E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E/Z)-SU-12662 hydrochloride. CAS No. 1261432-05-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-138813A. | |
| Ezurpimtrostat hydrochloride | Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GNS561 hydrochloride. CAS No. 1914148-73-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137978A. | |
| (E/Z)-Zotiraciclib | (E/Z)-Zotiraciclib ((E/Z)-TG02) is a potent inhibitor of CDK2, JAK2 and FLT3 with IC50s of 13, 73 and 56 nM, respectively. (E/Z)-Zotiraciclib effectively inhibits the proliferation of cancer cells, it can be used for the research of cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E/Z)-TG02; (E/Z)-SB1317. CAS No. 937270-47-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15166. | |
| F092 | F092 is an inhibitor of hematopoietic prostaglandin D synthase ( H-PGDS ) with a K D value of 0.14 nM. F092 can be used in the study of allergic and inflammatory responses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250261-59-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139171. | |
| F-1 | F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC 50 s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALK WT , ROS1 WT , ALK L1196M and ALK G1202R , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244775-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112801. | |
| F16 | F16 is a potent growth inhibitor of the neu -overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines. Uses: Scientific research. Group: Signaling pathways. CAS No. 36098-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100395. | |
| F5446 | F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304465-89-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-150190. | |
| F7H | F7H is a Frizzled receptor FZD7 antagonist ( IC 50 : 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 897109-93-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156095. | |
| Fabomotizole | Fabomotizole (CM346) is an insecticide with anxiolytic, antianxiety, and neuroprotective activities and a substrate of p-glycoprotein. Fabomotizole inhibits the ST-segment depression induced by isoproterenol in a rat model of acute subendocardial ischemia. Fabomotizole also inhibits Giardia lamblia and has the potential to inhibit giardiasis. Fabomotizole also targets Sigma1R , NRH:quinone reductase 2 (NQO2) , and MAO-A to exert anxiolytic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM346. CAS No. 173352-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-14895. | |
| Fabomotizole hydrochloride | Fabomotizole (CM346) hydrochloride is a compound with anxiolytic and neuroprotective activities. Fabomotizole (CM346) hydrochloride also has activity against Giardia lamblia and has the potential to inhibit giardiasis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM346 hydrochloride. CAS No. 173352-39-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14895A. | |
| FABP1-IN-1 | FABP1-IN-1 (44) is a selective FABP1 inhibitor, with an IC50 of 4.46 ?M. FABP1-IN-1 (44) can be used for the research of NASH[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3048021-44-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158127. | |
| FABPs ligand 6 | FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MF6. CAS No. 2988135-14-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145990. | |
| Factor D inhibitor 6 | Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC 50 of 30 nM and a K d of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1386455-51-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122700. | |
| FAD-dependent glucose dehydrogenase | FAD-dependent glucose dehydrogenase (EC 1.1.5.9), or glucose dehydrogenase (FAD)/Pseudomonas glucose dehydrogenase. Glucose 1-dehydrogenase is an enzyme used as a regeneration cofactor to convert glucose and NAD(P) into NAD(P)H and gluconic acid [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FAD-GDH; Glucose 1-dehydrogenase. CAS No. 37250-84-3. Pack Sizes: 1 KU. Product ID: HY-E70014. | |
| Fadraciclib | Fadraciclib (CYC065) is a second-generation, orally available ATP-competitive inhibitor of CDK2 / CDK9 kinases [1] with IC 50 s of 5 and 26 nM, respectively [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CYC065. CAS No. 1070790-89-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101212. | |
| Falcarindiol | Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties [1] [2]. Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Natural products. CAS No. 55297-87-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0364. | |
| Falcarinol | Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis [1]. Falcarinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Natural products. Alternative Names: Panaxynol; Carotatoxin. CAS No. 21852-80-2. Pack Sizes: 1 mg (40.92 mM * 100 μL in Ethanol). Product ID: HY-N1455. | |
| Faldaprevir | Faldaprevir (BI 201335) is a potent, orally active and selective noncovalent inhibitor of NS3/4A protease of HCV (hepatitis C virus) genotypes 1a and 1b, with K i values of 2.6 and 2.0 nM, respectively. Faldaprevir inhibits HCV RNA replication, with EC 50 values of 6.5 and 3.1 nM, respectively. Faldaprevir has potent antiviral activity against chronic HCV infection [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 201335. CAS No. 801283-95-4. Pack Sizes: 1 mg. Product ID: HY-15256. | |
| Falecalcitriol | Falecalcitriol(Fulstan; Hornel) is an analog of calcitriol; has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo. Uses: Scientific research. Group: Signaling pathways. CAS No. 83805-11-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-32342. | |
| FA-Leu-Gly-Pro-Ala-OH | FA-Leu-Gly-Pro-Ala-OH is a substrate of microbial collagenase[1]. Uses: Scientific research. Group: Peptides. CAS No. 78832-65-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2661. | |
| Fallypride | Fallypride is a potent antagonist of dopamine D2/D3 receptor. Fallypride, in the form of fallypride ( 18 F), can be used as a positron emission tomography (PET) radiotracer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 166173-78-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135497. | |
| Faltan | Faltan is a dicarboximide fungicide , widely used on vines and several vegetable crops, and is also cytotoxic effect on human bronchial epithelial cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133-07-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1878. | |
| FAM azide, 6-isomer | FAM azide, 6-isomer (6-FAM azide), a fluorescent dye, is a click chemistry reagent containing an azide group [1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 6-FAM azide. CAS No. 1386385-76-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1314. | |
| Famciclovir | Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 42810. CAS No. 104227-87-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17426. | |
| Famitinib | Famitinib (SHR1020), an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit , VEGFR-2 and PDGFRβ with IC 50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively [1]. Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR1020. CAS No. 1044040-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108713. | |
| Famotidine | Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-208. CAS No. 76824-35-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0377. | |
| Famoxadone | Famoxadone (DPX-JE874) is a fungicide acting against a broad spectrum of fungi and is widely used in Integrated Pest Management strategies in different agricultural crops [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPX-JE874. CAS No. 131807-57-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2008. | |
| Famprofazone | Famprofazone is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the pyrazolone series, and it has analgesic, anti-inflammatory, and antipyretic effects. Uses: Scientific research. Group: Signaling pathways. CAS No. 22881-35-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1054. | |
| Fanapanel | Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK200775; MPQX. CAS No. 161605-73-8. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15069. | |
| Fanapanel hydrate | Fanapanel hydrate (ZK200775 hydrate) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK200775 hydrate; MPQX hydrate. CAS No. 1255517-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15069A. | |
| Fangchinoline | Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing[1]. Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK[2]. Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer[3]. Uses: Scientific research. Group: Natural products. CAS No. 436-77-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N1372A. | |
| Fantofarone | Fantofarone is a highly potent Calcium Channel antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 33557. CAS No. 114432-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105117. | |
| FAPI-2 | FAPI-2 is a type of small molecule fibroblast activation protein inhibitor ( FAPI ) that targets the fibroblast activation protein (FAP) and has an inhibitory effect. This specific targeting ability makes FAPI-2 an effective tumor imaging agent, which can be used in cancer research. FAPI-2 can be used to synthesize 68Ga-FAPI-2 (a PET tracer) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2370952-98-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128642. | |
| FAPI-4 | FAPI-4 is a potent fibroblast activation protein (FAP) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. 68Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2374782-02-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128643. | |
| FAPI-46 | FAPI-46 is a quinoline-based fibroblast activation protein (FAP)-targeted tracer. Use radioactivity FAPI-46 labeled with 68Ga or 177Lu can be used for tumor imaging in a variety of cancers and has higher tumor uptake rates and longer tumor accumulation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2374782-04-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137331. | |
| FAPI-74 | FAPI-74 is a PET (positron emission tomography) tracer targeting the fibroblast activation protein (FAP). FAPI-74 can be used for FAP-positive tumor research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2374782-76-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147173. | |
| FAPI-mFS | FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu[1]. FAPI-mFS can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 3023869-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164725. | |
| FAP-IN-2 | FAP-IN-2 is a derivative of 99mTc-labeled isonitrile-containing fibroblast activation protein (FAPI) inhibitor. FAP-IN-2 can be used for tumor imaging. FAP-IN-2 has good stability, high uptake and good retention in the tumor site of mouse model[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2471983-20-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-47979. | |
| Faralimomab | Faralimomab (64G12) is an immunomodulator, and a murine anti- IFNA1 IgG1 mAb [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: 64G12. CAS No. 167816-91-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99611. | |
| Farampator | Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CX-691; Org24448. CAS No. 211735-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10937. | |
| Faricimab | Faricimab, an overall good safety and tolerability profile, is a bispecific antibody targeting Angiopoietin-2 ( Ang-2 ) and vascular endothelial growth factor-A ( VEGF-A ). Faricimab prevents retinal vascular leakage, cell death and inflammation in retinal ischemia/reperfusion (I/R) injury and sCNV mouse models. Faricimab demonstrates statistically superior visual acuity gains versus Ranibizumab (HY-P9951). Faricimab can be used for retinal diseases, such as age-related macular degeneration (w-AMD), diabetic macular edema (DME) and macular edema following retinal vein occlusion (RVO) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG7716. CAS No. 1607793-29-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99116. | |
| Farletuzumab | Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FR&alpha. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FR&alpha. Farletuzumab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORAb-003. CAS No. 896723-44-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99153. | |
| Farletuzumab ecteribulin | Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORAb-202. CAS No. 2407465-18-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99612. | |
| Farnesene (mixture of isomers) | Farnesene (mixture of isomers) is a farnesene with mixture of isomers. Farnesene is a herbivore-induced plant volatile (HIPV). Farnesene has an important effect on insect resistance in many plant species [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 125037-13-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-14620A. | |
| Farnesol | Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans , and has the activity in inhibiting bacteria. Uses: Scientific research. Group: Natural products. CAS No. 4602-84-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0248A. | |
| Farnesyl pyrophosphate ammonium | Farnesyl pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Farnesyl diphosphate ammonium. CAS No. 116057-57-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113037C. | |
| Faropenem sodium | Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122547-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76260. | |
| Farudodstat | Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. Farudodstat inhibits protein synthesis via activation of AP-1 transcription factors. Farudodstat induces apoptosis and substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASLAN003. CAS No. 1035688-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129239. | |
| Fasedienol | Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PH94B. CAS No. 23062-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145567. | |
| Fasiglifam | Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC 50 of 72 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-875. CAS No. 1000413-72-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10480. | |
| Fasinumab | Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor ( NGF ). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1190239-42-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99195. | |
| Fasnall | Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 ?M. Fasnall induces apoptosis in HER2+ breast cancer cell lines. Fasnall shows potent anti-tumor activities[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 929978-58-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-121250. | |
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