MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| GLPG3312 | GLPG3312 (Compound 28) is an orally active SIK inhibitor with IC50 values of 2.0 nM, 0.7 nM and 0.6 nM for SIK1, SIK2 and SIK3, respectively. GLPG3312 exhibits anti-inflammatory and immunomodulatory activity in vitro on human primary myeloid cells and in vivo in mouse models. GLPG3312 has good oral bioavailability and can be used for research on inflammatory and immune diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2340388-72-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157442. |  |
| GLPG3970 | GLPG3970 (compound 88) is a first-in-class SIK2/SIK3 inhibitor. GLPG3970 can be used for the research of inflammation and autoimmune disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2403733-82-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-150203. | |
| GLPG4970 | GLPG4970 is a potent, selective and orally active salt-inducible kinase 2/3 (SIK2/SIK3) dual inhibitor with IC50 values of 0.3 nM and 0.7 nM. GLPG4970 has weak inhibition of hERG channel with an IC50 of 29 μM. GLPG4970 can decrease TNFα release and increase IL-10 release GLPG4970 can be used for the researches of inflammation and immunology, such as colitis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3114869-49-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175479. | |
| GLS1 Inhibitor-1 | GLS1 Inhibitor-1 (Compound 27) is an orally active inhibitor for glutaminase 1 (GLS1) with an IC50 of 0.021 μM. GLS1 Inhibitor-1 inhibits the proliferation of PC-3 with an IC50 of 0.3 nM. GLS1 Inhibitor-1 exhibits antitumor efficacy against NCI-H1703 with GI50 of 0.011 μM. GLS1 Inhibitor-1 exhibits moderate pharmacokinetic characteristics[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1832646-52-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136704. | |
| (Glu2)-TRH | (Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH; HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 85541-78-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3960. | |
| Glu-Ala-Leu-Phe-Gln-pNA | Glu-Ala-Leu-Phe-Gln-pNA is a Chiba virus 3C-like protease (CVP) substrate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 198551-00-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P3794. | |
| Glu-AMS TEA | Glu-AMS TEA is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the Ki of 2.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1810728-44-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-159628A. | |
| Glucagon (1-29), bovine, human | Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucagon. CAS No. 16941-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0082. | |
| Glucagon (1-29), bovine, human hydrochloride | Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucagon hydrochloride. CAS No. 28270-04-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0082A. | |
| Glucagon (22-29) | Glucagon (22-29) is partial agonist of Glucagon (19-29). Glucagon specifically inhibits the Ca2+ pump in liver plasma membranes independently of adenylate cyclase activation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32204-93-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3617. | |
| Glucagon-like peptide 1 (1-37), human | Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GLP-1 (1-37) human. CAS No. 87805-34-3. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1145. | |
| Glucoamylase, Aspergillus niger | Amyloglucosidase, Aspergillus niger (Amyloglucosidase, Aspergillus niger) is a starch-hydrolyzing enzyme with high catalytic efficiency towards soluble starch and raw starch. Amyloglucosidase, Aspergillus niger hydrolyzes α-1,4 and α-1,6 glycosidic linkages in starch and similar substrates, and primarily releases β-glucose molecules from the non-reducing ends. Amyloglucosidase, Aspergillus niger participates in glycogen metabolism and is associated with type II glycogen storage disease. Amyloglucosidase, Aspergillus niger converts starch into glucose, and is applicable to the industrial production of high-fructose syrup, ethanol and other fermented products[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amyloglucosidase, Aspergillus niger. CAS No. 9032-08-0. Pack Sizes: 25 g. Product ID: HY-P2857. | |
| Glucocerebrosidase-IN-1 | Glucocerebrosidase-IN-1 (compound 11a) is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 can be used for the research of Gaucher disease (GD) and Parkinsons disease (PD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2279945-76-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147976. | |
| Glucocerebrosidase-IN-1 hydrochloride | Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 hydrochloride can be used for the research of Gaucher disease (GD) and Parkinsons disease (PD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2279945-77-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-147976A. | |
| Glucocorticoid receptor agonist-1 | Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2166375-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131974. | |
| Glucocorticoid receptor agonist-1 Ala-Ala-Mal | Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88) is a glucocorticosteroid, and an agonist of glucocorticoid receptor. Glucocorticoid receptor agonist-1 Ala-Ala-Mal can be conjugated with Adalimumab (HY-P9908) to prepare an ADC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2166376-51-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137882. | |
| Glucocorticoid receptor agonist-1 phosphate(2,6-difluoro) Ala-Ala-Br | Glucocorticoid receptor agonist-1 phosphate(2,6-difluoro) Ala-Ala-Br is an Drug-linker conjugates for ADC that can be used as a reaction reagent for the synthesis of anti-CD40 antibody agent conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2345733-40-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153345. | |
| Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br | Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br is a drug-linker conjugate for ADC that can be used to synthesize ABBV-154, ABBV-927, ABBV-368 or their analogs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2344809-82-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137883. | |
| Glucocorticoid receptor agonist-2 | Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2166378-92-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148435. | |
| Glucocorticoid receptor agonist-2 Ala-Ala-Mal | Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference for ABBV-3373[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2166376-64-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148436. | |
| Gluconasturtiin potassium | Gluconasturtiin potassium is a feeding activator for the larvae of P. maculipennis. High concentrations of Gluconasturtiin potassium are toxic to the larvae[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18425-76-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8468. | |
| Gluconate-13C6 sodium | Gluconate sodium-13C6 (D-Gluconic acid sodium salt-13C6) is the 13C-labeled Gluconate sodium (HY-B1092A). Gluconate sodium (D-Gluconic acid sodium salt) is an orally active glucose derivative. Gluconate sodium reduces nitric oxide and inflammatory cytokines (IL-1β and IL-6). Gluconate sodium inhibits ERK phosphorylation. Gluconate sodium has antioxidant and antiplatelet activation activities. Gluconate sodium has antitumor activity against colorectal cancer. Gluconate sodium improves osteoarthritis, intestinal damage and acute lung injury[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Gluconic acid-13C6 sodium; D-Gluconate-13C6 sodium. CAS No. 2687960-00-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W768336. | |
| Gluconate sodium | Gluconate sodium (D-Gluconic acid sodium salt) is an orally active glucose derivative. Gluconate sodium reduces nitric oxide and inflammatory cytokines (IL-1β and IL-6). Gluconate sodium inhibits ERK phosphorylation. Gluconate sodium has antioxidant and antiplatelet activation activities. Gluconate sodium has antitumor activity against colorectal cancer. Gluconate sodium improves osteoarthritis, intestinal damage and acute lung injury[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Gluconic acid sodium salt; Sodium D-gluconate; D-Gluconate sodium salt. CAS No. 527-07-1. Pack Sizes: 10 mM * 1 mL in Water; 10 g; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-B1092A. | |
| Glucoraphanin | Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects. Uses: Scientific research. Category: Signaling pathways. CAS No. 21414-41-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N4068. | |
| Glucoraphanin (Standard) | Glucoraphanin (Standard) is the analytical standard of Glucoraphanin. This product is intended for research and analytical applications. Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects. Uses: Scientific research. Category: Signaling pathways. CAS No. 21414-41-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N4068R. | |
| Glucoraphenin potassium | Glucoraphenin potassium is an orally effective glucosinolate. Glucoraphenin potassium can be isolated from radish sprouts. Glucoraphenin potassium enhances the enzymatic activity of Glutathione S-transferase. Glucoraphenin potassium enhances the activity of cytochrome P450-related monooxygenase[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 108844-81-1. Pack Sizes: 10 mg. Product ID: HY-N9348A. | |
| Glucosamine | Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Glucosamine; Chitosamine. CAS No. 3416-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B1125. | |
| Glucosamine-15N hydrochloride | Glucosamine-15N (hydrochloride) is the 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-(+)-Glucosamine-15N hydrochloride; Chitosamine-15N hydrochloride. CAS No. 42927-60-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0733S4. | |
| Glucosamine sulfate | Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Glucosamine sulfate. CAS No. 29031-19-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0487. | |
| Glucose-6-phosphate dehydrogenase, Bacillus sp. | Glucose-6-phosphate dehydrogenase, Bacillus sp. catalyzes the conversion of glucose-6-phosphate into 6-phosphogluconolactone, and produces reduced nicotinamide adenine dinucleotide phosphate (NADPH) and ribose-5-phosphate in this process. Glucose-6-phosphate dehydrogenase, Bacillus sp. can be used in research about diabetic complications[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G6PD, Bacillus sp. CAS No. 9001-40-5. Pack Sizes: 10 KU. Product ID: HY-125863C. | |
| Glucose-6-phosphate dehydrogenase, Microorganism | Glucose-6-phosphate dehydrogenase, Microorganism (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase, Microorganism is a primary source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, cytochrome p450 systems, and others. Glucose-6-phosphate dehydrogenase, Microorganism is applicable in research related to diabetes, endothelial dysfunction, cancer, and cardiomyopathy[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G6PD. CAS No. 9001-40-5. Pack Sizes: 1 KU; 5 KU. Product ID: HY-125863. | |
| Glucose 6-phosphate dehydrogenase (yeast, recombinant) | Glucose 6-phosphate dehydrogenase (yeast, recombinant) is the rate-limiting enzyme of the pentose phosphate pathway and a major source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems. Glucose 6-phosphate dehydrogenase helps cells resist oxidative stress and regulates metabolic rates. It holds potential for research in fields such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G6PD (yeast, recombinant). CAS No. 9001-40-5. Pack Sizes: 500 U. Product ID: HY-125863B. | |
| Glucose dehydrogenase, recombinant Microorganisms | Glucose dehydrogenase, recombinant Microorganisms is a FDA-dependent oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP+ to NADPH or, to a lesser extent, NAD+ to NADH. Glucose dehydrogenase (GDH) accepts both NAD+ and NADP+ as cofactors and can be used for the regeneration of NADH and NADPH[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9028-53-9. Pack Sizes: 1 KU. Product ID: HY-P3186. | |
| Glucose oxidase | Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-37-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2902. | |
| Glucosylceramide, plant | Glucosylceramide, plant is a plant-derived glycolipid with anti-inflammatory and immunomodulatory activities. Glucosylceramide, plant plays an important role in promoting cell proliferation and repair. Glucosylceramide, plant is widely used in skin care products to enhance skin barrier function. Glucosylceramide, plant has also been studied for improving nervous system health, showing potential neuroprotective effects. Uses: Scientific research. Category: Signaling pathways. CAS No. 497155-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W717504. | |
| Glucosylceramide synthase-IN-2 | Glucosylceramide synthase-IN-2 (compound T-690) is a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 15 nM and 190 nM for human GCS and mouse GCS, respectively.Glucosylceramide synthase-IN-2 exhibits noncompetitive type inhibition with C8-ceramide and UDP-glucose.Glucosylceramide synthase-IN-2 can be used for Gaucher's disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2597958-02-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144267. | |
| Glucosylsphingosine | Glucosylsphingosine (lyso-Gb1) is a deacylated form of glucosylceramide with neurotoxicity and is also a noncompetitively inhibitor of glucocerebrosidase with a Ki value of 30 μM. Glucosylsphingosine is promising for research of Krabbe and Gaucher disease[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucopsychosine; Lyso-Gb1; Lyso-GL1. CAS No. 52050-17-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7745. | |
| Glufosinate ammonium | Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium exerts neurotoxic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77182-82-2. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-W019870. | |
| Glufosinate ammonium (Standard) | Glufosinate (ammonium) (Standard) is the analytical standard of Glufosinate (ammonium). This product is intended for research and analytical applications. Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium exerts neurotoxic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77182-82-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W019870R. | |
| Glufosinate-d3 hydrochloride | Glufosinate-d3 (hydrochloride) is a deuterium labeled compound. Uses: Scientific research. Category: Signaling pathways. CAS No. 1323254-05-2. Pack Sizes: 1 mg. Product ID: HY-152055S. | |
| Glu-Glu | Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-Glu-Glu-OH; Glutamyl-glutamic acid. CAS No. 3929-61-1. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-W016012. | |
| Glumetinib | Glumetinib (SCC244) is a highly selective, orally bioavailable, ATP-competitive c-Met inhibitor with an IC50 of 0.42 nM. Glumetinib has greater than 2400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member RON and highly homologous kinases Axl, Mer, TyrO3. Antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gumarontinib; SCC244. CAS No. 1642581-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-116000. | |
| GLUT4-IN-2 | GLUT4-IN-2 is a potent and selective GLUT4 inhibitor with IC50s of 11.4 μM and 6.8 μM for GLUT1 and GLUT4, respectively. GLUT4-IN-2 induces cell apoptosis and cell cycle arrest at G0/G1phase. GLUT4-IN-2 shows potent antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2454113-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146980. | |
| Glutamate carboxypeptidase | Glutamate carboxypeptidase is an endo/exopeptidase targeting folate and antifolate agents. Glutamate carboxypeptidase regulates intracellular folate homeostasis by hydrolyzing γ-polyglutamate chains. Glutamate carboxypeptidase is promising for research of antifolate agents and cancers[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carboxypeptidase G. CAS No. 9074-87-7. Pack Sizes: 5 U. Product ID: HY-P2938. | |
| Glutamate dehydrogenase | Glutamate dehydrogenase is an enzyme in both prokaryotes and eukaryotic mitochondria. Glutamate dehydrogenase can be used for the enzymatic determination of ammonia, alpha-ketoglutaric acid, L-glutamate and urease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-46-1. Pack Sizes: 1 KU. Product ID: HY-E70003. | |
| Glutamate dehydrogenase (NAD(P)) | Glutamate dehydrogenase NAD(P) (GLDH) can be found in hepatocytes, renal tissue, brain, muscle, and intestinal cells. Glutamate dehydrogenase NAD(P) is often used in biochemical studies. Glutamate dehydrogenase is a mitochondrial enzyme, it catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-KG) as part of the urea cycle[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GLDH. CAS No. 9029-12-3. Pack Sizes: 5 KU; 10 KU. Product ID: HY-P2911. | |
| Glutamate oxidase | Glutamate oxidase (L-Glutamate oxidase) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Glutamate oxidase is expressed in E. Coli. Glutamate oxidase can be used to produce α-ketoglutaric acid from l-glutamic acid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Glutamate oxidase. CAS No. 39346-34-4. Pack Sizes: 1 U. Product ID: HY-P3263. | |
| Glutaminase C-IN-1 | Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Compound 968. CAS No. 311795-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12682. | |
| Glutaric acid-d4 | Glutaric acid-d4 is the deuterium labeled Glutaric acid. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19136-99-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W008820S1. | |
| Glutaric acid-d6 | Glutaric acid-d6 is the deuterium labeled Glutaric acid. Glutaric acid is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154184-99-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W008820S. | |
| Glutaryl coenzyme A lithium | Glutaryl coenzyme A lithium is an important endogenous metabolites. Glutaryl coenzyme A lithium can be used in HMG-CoA or Glutaryl-CoA related experiment. Uses: Scientific research. Category: Signaling pathways. CAS No. 103192-48-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141474. | |
| Glutathione ethyl ester | Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92614-59-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134124. | |
| Glutathione oxidized | Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Glutathione oxidized; GSSG; Oxiglutatione. CAS No. 27025-41-8. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-D0844. | |
| Glutathione oxidized-13C4,15N2 | Glutathione oxidized-13C4,15N2 is the 13C and 15N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Glutathione oxidized-13C4,15N2; GSSG-13C4,15N2; Oxiglutatione-13C4,15N2. CAS No. 1416898-83-3. Pack Sizes: 1 mg. Product ID: HY-D0844S. | |
| Glutathione oxidized (Standard) | Glutathione oxidized (Standard) is the analytical standard of Glutathione oxidized. This product is intended for research and analytical applications. Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Glutathione oxidized (Standard); GSSG (Standard); Oxiglutatione (Standard). CAS No. 27025-41-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-D0844R. | |
| Glutathione Peroxidase | Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H2O. Glutathione Peroxidase is an effective antioxidant against oxidative stress[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSH-Px; EC 1.11.1.9. CAS No. 9013-66-5. Pack Sizes: 100 U. Product ID: HY-P2833. | |
| Glutathione Reductase, baker's yeast | Glutathione reductase, baker's yeast (EC 1.6.4.2) is a reductase. Glutathione reductase, baker's yeast eliminates intracellular ROS. Glutathione reductase, baker's yeast reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as an electron donor. Glutathione reductase, baker's yeast exerts antioxidant activity. Glutathione reductase is mainly used to study diseases associated with oxidative stress, such as Parkinson's disease and sickle cell anemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 1.6.4.2; GR. CAS No. 9001-48-3. Pack Sizes: 100 U. Product ID: HY-125862. | |
| Glutathione sulfonate | Glutathione sulfonate (S-Sulfoglutathione) is a multifunctional bioactive compound that inhibits angiogenesis and tumor growth. Glutathione sulfonate is a competitive inhibitor of glutathione S-transferase and is involved in the detoxification process and the binding of a variety of exogenous and endogenous compounds. Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism. The structural characteristics of Glutathione sulfonate contribute to its inhibitory effect by hydrogen bonding in the active center of the enzyme[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-Sulfoglutathione. CAS No. 1637-70-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-167920. | |
| Glutathione synthesis-IN-1 | Glutathione synthesis-IN-1 (DC-1) is a glutathione synthesis inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2632968-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144868. | |
| Glutaurine | Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Litoralon. CAS No. 56488-60-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-106608. | |
| GLUT inhibitor-1 | GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2421141-40-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139605. | |
| Glutor | Glutor is a selective GLUT 1/2/3 inhibitor that can suppress glucose uptake. Glutor can inhibit glycolysis and has anti-tumor activity, inducing cell apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2561471-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158302. | |
| GLX351322 | GLX351322 is an inhibitor of NADPH oxidase 4 (Nox4), and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 835598-94-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100111. | |
| GLX481304 | GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 701224-63-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153977. | |
| (Gly14)-Humanin (human) | (Gly14)-Humanin (human) (14-Glycine-Humanin (human)) is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly). (Gly14)-Humanin (human) has anti-apoptotic and neuroprotective functions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 14-Glycine-Humanin (human). CAS No. 330936-70-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3993. | |
| Gly3-VC-PAB-MMAE | Gly3-VC-PAB-MMAE consists a cleavable ADC linker (Gly3-VC-PAB) and a potent tubulin inhibitor (MMAE). Gly3-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2684216-48-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-131056. | |
| Gly-Arg-Gly-Asp-Ser | Gly-Arg-Gly-Asp-Ser (GRGDS) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ~5 and ~6.5 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GRGDS. CAS No. 96426-21-0. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0295. | |
| Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide | Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide (GD4K-na) is a substrate for human enteropeptidase (Km: 0.16 mM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GD4K-na. CAS No. 70023-02-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2660. | |
| Glyburide-d11 | Glyburide-d11 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity[1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR)[3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability[4]. Glibenclamide can induce autophagy[5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1189985-02-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15206S. | |
| Glycerol | Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Trihydroxypropane. CAS No. 56-81-5. Pack Sizes: 100 mL; 10 mM * 1 mL in DMSO; 500 mL. Product ID: HY-B1659. | |
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