MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Glycerol-13C3 | Glycerol-13C3 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Trihydroxypropane-13C3. CAS No. 63346-81-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1659S5. |  |
| Glycerol-3-phosphate dehydrogenase, microorganism | Glycerol-3-phosphate dehydrogenase, microorganism (GPDH, microorganism) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate to sn-glycerol 3-phosphate.Glycerol-3-phosphate dehydrogenase is a glycolytic enzyme and is responsible for the re-oxidation of NADH to NAD+ and energy supply[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GPDH, microorganism; α-Glycerophosphate dehydrogenase, microorganism; Glycerol phosphate dehydrogenase, microorganism. CAS No. 9075-65-4. Pack Sizes: 1 KU. Product ID: HY-P2765A. | |
| Glycerol-3-phosphate dehydrogenase, rabbit muscle | Glycerol-3-phosphate dehydrogenase, rabbit muscle (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate to sn-glycerol 3-phosphate. Glycerol-3-phosphate dehydrogenase is a glycolytic enzyme and is responsible for the re-oxidation of NADH to NAD+ and energy supply[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GPDH; α-Glycerophosphate dehydrogenase; Glycerol phosphate dehydrogenase. CAS No. 9075-65-4. Pack Sizes: 1 KU. Product ID: HY-P2765. | |
| Glycerol-3-phosphate oxidase, E. coli | Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase, E. coli is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase, E. coli produces electrons through oxidation. Glycerol-3-phosphate oxidase, E. coli is an enzyme with important functions in the field of biochemistry, and is widely used in medical testing and scientific research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GPO. CAS No. 9046-28-0. Pack Sizes: 100 U; 500 U. Product ID: HY-P2733. | |
| Glycerol-3-phosphate oxidase, microorganism | Glycerol-3-phosphate oxidase, microorganism is an enzyme that catalyzes the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate, producing hydrogen peroxide in the process. Glycerol-3-phosphate oxidase is located in the mitochondria of microorganisms and is involved in the glycerol-3-phosphate cycle, regulating cellular energy metabolism. Glycerol-3-phosphate oxidase, microorganism can be used in conjunction with Lipoprotein Lipase and Glycerol Kinase to determine triglyceride levels[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GPO, microorganism. CAS No. 9046-28-0. Pack Sizes: 1 KU. Product ID: HY-P2733C. | |
| Glycerol kinase, microorganism | Glycerol kinase, microorganism (GyK) acts as a NR4A1 inhibitor with enzymatic activity. It directly binds to and inhibits the transcription factor NR4A1, thereby negatively regulating hepatic gluconeogenesis and reducing blood glucose levels. Glycerol kinase, microorganism positively regulates UCP1 expression via partial dependence on the β-adrenergic receptor-cAMP-CREB pathway, promotes browning of white adipose tissue and thermogenesis, and further modulates intracellular fatty acid composition and energy metabolism. In diabetic mouse models, overexpression of Glycerol kinase effectively antagonizes NR4A1-induced hyperglycemia, demonstrating potential for improving glucose homeostasis. Glycerol kinase, microorganism can be used for studies on diabetes and obesity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GyK. CAS No. 9030-66-4. Pack Sizes: 500 U; 1 KU. Product ID: HY-P2917. | |
| Glycerophosphocholine | Glycerophosphocholine ((S)-Glycerolphosphocholine) is an orally active metabolite that crosses the blood-brain barrier. Glycerophosphocholine acts as a precursor of acetylcholine, a specific marker for phosphatidylcholine breakdown, a major water-soluble storage form of choline, and an intermediate in phosphatidylcholine metabolism. Glycerophosphocholine is specifically elevated in the cerebrospinal fluid of Alzheimer's disease models, and it also promotes growth hormone secretion and fat oxidation. Glycerophosphocholine is also a potential biomarker for breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Glycerolphosphocholine. CAS No. 4217-84-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W096638A. | |
| Glycerophosphoinositol choline | Glycerophosphoinositol choline is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 425642-32-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1337B. | |
| Glycine | Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine inhibits the membrane aggregation of NINJ1 and prevents plasma membrane rupture during cell death. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56-40-6. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-Y0966. | |
| Glycine-1-13C | Glycine-1-13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Category: Signaling pathways. CAS No. 20110-59-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-Y0966S4. | |
| Glycine-d2 | Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Category: Signaling pathways. CAS No. 4896-75-7. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-Y0966S1. | |
| Glycine-d3 | Glycine-d3 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Category: Signaling pathways. CAS No. 4896-76-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-Y0966S10. | |
| Glycine-d5 | Glycine-d5 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Category: Signaling pathways. CAS No. 4896-77-9. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg. Product ID: HY-Y0966S8. | |
| Glycine (Standard) | Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56-40-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0966R. | |
| Glycochenodeoxycholic acid | Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Chenodeoxycholylglycine. CAS No. 640-79-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N2334. | |
| Glycochenodeoxycholic acid 3-sulfate disodium | N-β-D-Glucopyranosyloctanamide is a biochemical assay reagent. Uses: Scientific research. Category: Signaling pathways. CAS No. 66874-09-7. Pack Sizes: 2.5 mg. Product ID: HY-W587911. | |
| Glycochenodeoxycholic acid-d4 | Glycochenodeoxycholic acid-d4 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Chenodeoxycholylglycine-d4. CAS No. 1201918-16-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2334S. | |
| Glycochenodeoxycholic acid sodium salt | Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate. CAS No. 16564-43-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-N2334A. | |
| Glycocholic acid | Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 475-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-N1423. | |
| Glycocholic acid-d4 | Glycocholic acid-d4 is the deuterium labeled Glycocholic acid (HY-N1423). Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA). Uses: Scientific research. Category: Signaling pathways. CAS No. 1201918-15-1. Pack Sizes: 1 mg. Product ID: HY-N1423S. | |
| Glycocholic acid sodium | Glycocholic acid sodium is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid sodium inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid sodium modulates related bile acid receptor signaling. Glycocholic acid sodium suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid sodium can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 863-57-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-N1423A. | |
| Glycocyamine-d2 | Glycocyamine-d2 (Guanidinoacetic acid-d2) is the deuterium labeled Glycocyamine (HY-W021448). Glycocyamine is a direct precursor of creatine and an orally active energy metabolism regulator and myogenic differentiation inducer. Glycocyamine can activate the Akt/mTOR/S6K signaling pathway via miR-133a-3p and miR-1a-3p, and stimulate the mRNA expression of myogenic differentiation factor 1 (MyoD) and myopoietin (MyoG). Glycocyamine can increase muscle creatine concentration and maintain ATP homeostasis through the creatine phosphate/creatine kinase system. Glycocyamine can be used in research on feed additives for poultry farming. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Guanidinoacetic acid-d2. CAS No. 1173020-63-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W021448S. | |
| Glycodeoxycholate Sodium | Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium glycyldeoxycholate. CAS No. 16409-34-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-N1427. | |
| Glycodeoxycholic acid | Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 360-65-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-125731. | |
| Glycogen, from rabbit liver, ≥85% | Glycogen, from rabbit liver, ≥85% is glycogen extracted from rabbit liver. Glycogen, from rabbit liver, ≥85% is a branched polysaccharide condensed from glucose and serves as a storage form of glucose in the body. Glycogen, from rabbit liver, ≥85% plays an important role in physiological processes such as maintaining blood sugar and providing energy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9005-79-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113511B. | |
| Glycogen phosphorylase-IN-1 | Glycogen phosphorylase-IN-1 (Compound 42) is an inhibitor for human liver glycogen phosphorylase (hlGPa) and hepatocyte glycogen-derived glucose production with IC50s of 53 and 380 nM, respectively. Glycogen phosphorylase-IN-1 reveals efficacy towards type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 648926-15-2. Pack Sizes: 1 mg. Product ID: HY-128029. | |
| Glycohyocholic acid | Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Hyocholic acid (HY-121238) and Glycine (HY-Y0966). Glycohyocholic acid can be used as a biomarker in the study of hepatitis C-related cirrhosis and diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GHCA. CAS No. 32747-08-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122141. | |
| Glycohyodeoxycholic acid | Glycohyodeoxycholic acid is a glycine-conjugated bile acid and also a metabolite of Hyodeoxycholic acid (HY-N0169). The serum level of Glycohyodeoxycholic acid is negatively correlated with the severity of non-alcoholic fatty liver disease. Glycohyodeoxycholic acid can be used in research related to non-alcoholic fatty liver disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13042-33-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126995. | |
| Glycol chitosan | Glycol chitosan is a chitosan derivative with ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is biocompatible and biodegradable[1][2][3]. Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 μg/mL, 32 μg/mL and <0.5 μg/mL, respectively[4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123938-86-3. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-135969. | |
| Glycolic acid-d2 | Glycolic acid-d2 is the deuterium labeled Glycolic acid. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour. Uses: Scientific research. Category: Signaling pathways. CAS No. 75502-10-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-W015967S. | |
| Glycolithocholic acid | Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lithocholylglycine. CAS No. 474-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116374. | |
| Glycolithocholic acid 3-sulfate | Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycolithocholate sulfate; Sulfolithocholylglycine; SLCG. CAS No. 15324-64-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113074. | |
| Glycolithocholic acid-d4 | Glycolithocholic acid-d4 is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2044276-16-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-116374S. | |
| Glycolithocholic acid sodium | Glycolithocholic acid (Lithocholylglycine) sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lithocholylglycine sodium. CAS No. 24404-83-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116374A. | |
| Glycopyrrolate | Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. Glycopyrrolate has bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycopyrronium bromide; Glycopyrrolate bromide. CAS No. 596-51-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17465. | |
| Glycoursodeoxycholic acid | Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GUDCA; Ursodeoxycholylglycine. CAS No. 64480-66-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-N1424. | |
| Glycoursodeoxycholic acid-d4 | Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ursodeoxycholylglycine-d4. CAS No. 2044276-17-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1424S. | |
| Glycycoumarin | Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 94805-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N4113. | |
| Glycyl-Exatecan TFA | Glycyl-Exatecan TFA (Glycyl-DX-8951 TFA), a derivative of Exatecan (HY-13631), is an anticancer agent. Glycyl-Exatecan TFA has significantly antitumor activity. Glycyl-Exatecan TFA can be used for cancers like solid tumors research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycyl-DX-8951 TFA; Exatecan analog 2 TFA. CAS No. 1883333-57-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128995A. | |
| Glycyl-L-histidyl-L-lysine | Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance[1][2][3]. Uses: Scientific research. Category: Peptides. Alternative Names: GHK; Tripeptide-1. CAS No. 49557-75-7. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-P0046. | |
| Glycyl-L-proline | Glycyl-L-proline (H-Gly-Pro-OH) is a dipeptide. Glycyl-L-proline can induce MCF-7 cells apoptosis. Glycyl-L-proline can enhance the inhibitory effect of the PRODH/POX knockout on collagen and DNA biosynthesis. Glycyl-L-proline can inhibit Gly-Sar and L-proline transport. Glycyl-L-proline can be used for the researches of cancer and metabolic disease, such as breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-Gly-Pro-OH; Gly-Pro. CAS No. 704-15-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-W016887. | |
| Glycyl-L-proline (Standard) | H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-Gly-Pro-OH (Standard); Gly-Pro (Standard). CAS No. 704-15-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016887R. | |
| Glycyrrhizic acid | Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycyrrhizin. CAS No. 1405-86-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-N0184. | |
| Glycyrrhizic acid (Standard) | Glycyrrhizic acid (Standard) is the analytical standard of Glycyrrhizic acid. This product is intended for research and analytical applications. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycyrrhizin (Standard). CAS No. 1405-86-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0184R. | |
| Gly-Gly-Gly-PEG2-azide | Gly-Gly-Gly-PEG2-azide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2222277-20-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-157275. | |
| Gly-Gly-Gly-PEG3-TCO | Gly-Gly-Gly-PEG3-TCO is a 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2353409-81-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141190. | |
| Gly-Gly-Gly-PEG4-azide | Gly-Gly-Gly-PEG4-azide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 3070260-22-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145066. | |
| Gly-Gly-Gly-PEG4-DBCO | Gly-Gly-Gly-PEG4-DBCO is a 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2353409-80-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140309. | |
| Gly-Gly-Gly-PEG4-methyltetrazine | Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2353409-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-141284. | |
| Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599440-20-6. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-45672. | |
| Gly-Gly-Phe-Gly-NH-O-CO-Exatecan | Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a Drug-Linker Conjugates for ADC, consiting of an ADC linker and Exatecan (HY-13631) (topoisomerase I inhibitor). Gly-Gly-Phe-Gly-NH-O-CO-Exatecan can be used for ADC molecues synthesis. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599440-12-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631M. | |
| GlyH-101 | GlyH-101 is a potent CFTR inhibitor. GlyH-101 also is a potent and reversible inhibitor of the VSORC conductance. GlyH-101 shows antiproliferative activity. GlyH-101 inhibits CFTR-like current and VSORC current[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 328541-79-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18336. | |
| Gly-His-Lys acetate | Gly-His-Lys acetate is a natural, circulating regulatory and antimicrobial tripeptide derived from extracellular matrix proteins. Gly-His-Lys acetate binds Cu2+ to support copper enzyme activation, antioxidant processes, cellular bioenergetics, and the synthesis of elastin, collagen and catecholamines. Gly-His-Lys acetate regulates cell growth, differentiation and tissue repair, and exerts regenerative, anxiolytic, anti-inflammatory, analgesic and immunosuppressive activities. Gly-His-Lys acetate induces liver degenerative changes. Gly-His-Lys acetate can be used for the research of infections, anxiety, pain-related behaviors and immune-associated liver diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72957-37-0. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W010989. | |
| Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide | Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide is the drug-linker conjugate for ADC, containing ADC linker Gly-Mal-GGFG and ADC cytotoxin Deruxtecan 2-hydroxypropanamide[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750623-07-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153892. | |
| Glyoxal (40% w/w in water) | Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs). Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 107-22-2. Pack Sizes: 25 mL; 10 mM * 1 mL in DMSO; 50 mL; 100 mL. Product ID: HY-Y0785. | |
| Gly-Phe-AMC | Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 201852-70-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4425. | |
| Gly-Phe-β-naphthylamide | Gly-Phe-β-naphthylamide is a substrate of Cathepsin C (HY-P2922) and belongs to the lysosomal agonist. Gly-Phe-β-naphthylamide can freely pass through the cell membrane and organelle membrane. Gly-Phe-β-naphthylamide will be specifically hydrolyzed by Cathepsin C, ultimately leading to a permeability lysis when it enters the acidic compartment. Gly-Phe-β-naphthylamide can be used to study lysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21438-66-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-W011063. | |
| Glyphosate | Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1071-83-6. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-B0863. | |
| Glyphosate-13C2,15N | Glyphosate-13C2,15N is the 13C and 15N labled Glyphosate (HY-B0863). Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1185107-63-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0863S3. | |
| Glyphosate-d2 | Glyphosate-d2 is the deuterium labeled Glyphosate. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2733532-11-9. Pack Sizes: 1 mg. Product ID: HY-B0863S. | |
| Glyphosate (Standard) | Glyphosate (Standard) is the analytical standard of Glyphosate. This product is intended for research and analytical applications. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1071-83-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0863R. | |
| Gly-Pro-AMC hydrobromide | Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 115035-46-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137834. | |
| Gly-Pro-pNA hydrochloride | Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103213-34-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-119244. | |
| GlyRS-IN-1 | GlyRS-IN-1 is a glycyl-tRNA synthase (GlyRS) inhibitor extracted from patent WO 2017066459 A1. GlyRS-IN-1 can also inhibit the growth of bacteria[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112921-11-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108940. | |
| GM-60186 | GM-60186 is a 5-HT receptor 2B (HTR2B) inhibitor with an IC50 of 257 nM. GM-60186 significantly inhibits colorectal cancer proliferation and migration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3097453-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169229. | |
| GM-90257 | GM-90257 is a microtubule acetylation inhibitor. GM-90257 binds directly to α-tubulin. GM-90257 prevents the recruitment of α-tubulin acetyltransferase 1 (αTAT1) to the K40 residue in α-tubulin. GM-90257 causes Apoptosis, downregulates BCl-2, and activates JNK and PARP. GM-90257 has anticancer activity against breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 315703-81-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-155956. | |
| GMB-475 | GMB-475 is a potent BCR-ABL1 PROTAC based on Von Hippel-Lindau (VHL). GMB-475 targets the nutmeg pocket of ABL1 in an ectopic manner and degrades BCR-ABL1 protein through the ubiquitin proteasome pathway. GMB-475 inhibits the proliferation of human K562 cells and mouse Ba/F3 cells, and is used for the study of chronic myeloid leukemia. (Blue: VHL ligand (HY-125845); Black: Linker; Pink: BCR-ABL1 ligand (HY-11007))[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2490599-18-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125834. | |
| GMQ hydrochloride | GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Guanidine-4-methylquinazoline hydrochloride. CAS No. 5361-15-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107757. | |
| GN25 | GN25 is a specific p53-Snail binding inhibitor with antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1227401-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117280. | |
| GN44028 | GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1α inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of cancers[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1421448-26-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110266. | |
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