MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Gepirone hydrochloride | Gepirone is a selective 5-HT1A agonist. Gepirone binds selectively to 5-HT1A receptor binding site. Gepirone acts as an antidepressant agent can be used for anxiety and major depressive disorder research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83928-66-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122422A. |  |
| Gepotidacin | Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK2140944. CAS No. 1075236-89-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16742. | |
| Geraldol | Geraldol is a Flavonoids product that can be isolated from the herbs of Lotus corniculatus L.[1]. Uses: Scientific research. Category: Natural products. CAS No. 21511-25-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8742. | |
| Geranial | Geranial is an aromatic compound. It can be isolated from the fruits of Litsea cubeba Lour and the rhizomes of ginger (Zingiber officinale). Geranial inhibits LPS-induced phosphorylation of ERK1/2, JNK1/3 and IκB in macrophages. It suppresses the secretion of IL-1β, TNF-α and IL-6, as well as the expression of pro-IL-1β, iNOS and COX-2. Geranial increases ROS. It can be used in the research of inflammatory diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-3,7-Dimethylocta-2,6-dienal. CAS No. 141-27-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W1000105. | |
| Geranic acid | Geranic acid (Geranate) acts as a tyrosinase inhibitor and antifungal agent, with an IC50 value of 0.14-2.3 mM against mushroom tyrosinase. Geranic acid reduces the viability of human pancreatic cancer cells and B-lymphoma cells. Geranic acid inhibits mycelial growth of the maize pathogens Colletotrichum graminicola and Fusarium graminearum. Geranic acid is applicable to research related to fungal infections, pancreatic cancer and B-lymphoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Geranate; NSC 229335; GAGE. CAS No. 459-80-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W115529. | |
| Geraniin | Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, and anti-hyperglycemic activities, with an IC50 of 43 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 60976-49-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0472. | |
| Geraniol | Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Induced disease models products. CAS No. 106-24-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-N6952. | |
| Geraniol-d6 (Major) | Geraniol-d6 (Major) is the deuterated labeled Geraniol (Major). Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1660976-93-1. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-W782079. | |
| Geranyl diphosphate triammonium | Geranyl diphosphate triammonium is a key intermediate in the isoprenoid biosynthesis pathway (IBP). Geranyl diphosphate triammonium plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Geranyl pyrophosphate triammonium. CAS No. 116057-55-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-114295A. | |
| Geranylgeraniol | Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 24034-73-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-W011474. | |
| Geranylgeraniol (Standard) | Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 24034-73-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011474R. | |
| Geranylgeranyl pyrophosphate triammonium | Geranylgeranyl pyrophosphate triammonium is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate triammonium is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate triammonium regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313263-08-0. Pack Sizes: 250 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-126370A. | |
| GERI-BP002-A | GERI-BP002-A is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) produced by Aspergillus fumigatus F93, which can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 119-47-1. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-121254. | |
| Germacrene D | Germacrene D is isolated from Solidago canadensis. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23986-74-5. Pack Sizes: 250 μg (4.89 mM * 250 μL in Heptane); 500 μg (4.89 mM * 500 μL in Heptane); 1 mg (4.89 mM * 1 mL in Heptane). Product ID: HY-125685. | |
| Gersizangitide | Gersizangitide (AXT107) is an anti-angiogenic peptide consisting of 20 amino acids, derived from collagen IV. Gersizangitide is an inhibitor of VEGF-A and VEGF-C and an activator of Tie2. Gersizangitide can block VEGF receptor signaling, inhibit vascular leakage, neovascularization and inflammation. Gersizangitide can be used in the research of diseases related to ocular neovascularization and angiogenesis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AXT-107. CAS No. 2417491-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3369. | |
| Gevokizumab | Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1129435-60-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99171. | |
| GFB-8438 | GFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively. GFB-8438 shows excellent selectivity against TRPC6, other TRP family members, NaV 1.5, as well as limited activity against the hERG channel. GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2304549-73-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133012. | |
| GFH018 | GFH018 is an orally active, selective and ATP-competitive TGF-βR1 inhibitor with an IC50 of 40 nM. GFH018 reactivates the immune system by blocking the immunosuppression mediated by regulatory T cells and M2 macrophages. GFH018 inhibits tumor angiogenesis. GFH018 suppresses tumor growth in mouse tumor models. GFH018 can be used for the research of solid tumors, hepatocellular carcinoma, colorectal cancer, breast cancer, and relapsed/metastatic nasopharyngeal carcinoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2169299-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160215. | |
| GFOGER peptide | GFOGER peptide is an artificially synthesized collagen-mimetic sequence. GFOGER peptide acts as a ligand for α2β1, α11β1 and α1β1 integrins, thereby supporting integrin-mediated cell adhesion to collagen. GFOGER peptide triggers signaling pathways mediated by the α2β1 integrin receptor and upregulates osteoblast differentiation. GFOGER peptide accelerates and enhances bone formation at sites of refractory femoral defects. GFOGER peptide can be passively adsorbed onto polymer scaffolds for cell-free/growth factor-free bone formation. GFOGER peptide is used in biomaterials such as hydrogels and 3D bioinks for tissue engineering research including bone formation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 245120-10-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P11328. | |
| GFP11 | GFP11 is a protein fusion tag consisting of 16 amino acids. When GFP11 and GFP1-10 are sufficiently close in physical space, they undergo spontaneous, irreversible complementation to reassemble into an intact, functional GFP protein that emits green fluorescence. GFP11 can be used to form a split GFP system for high-throughput biotechnology and flow cytometry applications[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862973-56-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P11329. | |
| GGFG-amide-glycol-amide-Exatecan | GGFG-amide-glycol-amide-Exatecan (Intermediate 2) is an Exatecan (HY-13631) derivative and can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2866301-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-153600. | |
| GGFG-PAB-Exatecan | GGFG-PAB-Exatecan consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 251459-32-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153069. | |
| GGFG-PAB-MMAE | GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC. GGFG-PAB-MMAE contains the ADC linker (GGFG-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3049886-19-0. Pack Sizes: 5 mg. Product ID: HY-164788. | |
| GGsTop | GGsTop (Nahlsgen) is a potent, non-toxic, highly selective and irreversible γ-GGT inhibitor, with a Ki of 170 μM for Human GGT. GGsTop shows a pKa of 9.71, also exhibits Kons of 150 and 51 M-1 s-1 against E.coli GGT and human GGT, respectively. GGsTop protects hepatic ischemia-reperfusion injury in rat model[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nahlsgen. CAS No. 926281-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108467. | |
| GGTI-2133 | GGTI-2133, a peptidomimetic, is a selective geranylgeranyltransferase I (GGTase-I) inhibitor with an IC50 of 38 nM. GGTI-2133 shows 140-fold selectivity over farnesyltransferase (FTase) (IC50 of 5.4 μM). GGTI-2133 inhibits the geranylation of Rap-1A with an IC50 of 10 μM. GGTI-2133 can be used for the study of eosinophilic airway inflammation such as asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 191102-79-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12369. | |
| GGTI-2154 hydrochloride | GGTI-2154 hydrochloride is a potent and selective inhibitor geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM. GGTI-2154 hydrochloride shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM). GGTI-2154 hydrochloride can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 478908-50-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16229A. | |
| GGTI-2417 | GGTI-2417 is a potent and selective inhibitor of GGTase I. GGTI-2417 inhibits the Cdk2-mediated phosphorylation of p27Kip1 at Thr187 and accumulates p27Kip1 in the nucleus. GGTI-2417 also induces breast cancer cell apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 501010-05-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16230. | |
| GGTI-2418 | GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 501010-06-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16231. | |
| GGTI298 Trifluoroacetate | GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1217457-86-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15871. | |
| GHP-88309 | GHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses, that targets the viral polymerase, interupts the viral RNA synthesis, and inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with EC50 of 0.06-1.2 μM. GHP-88309 exhibits anti-infectious efficacy in mouse models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1269267-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-170395. | |
| GI254023X | GI254023X is a potent MMP9 and ADAM10 inhibitor with IC50s of 2.5 and 5.3 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GI4023; SRI028594. CAS No. 260264-93-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19956. | |
| Gibberellic acid | Gibberellic acid (GA3) is a natural plant growth regulator with oral bioactivity. Gibberellic acid governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid can be used in studies of plant growth, metabolism, and abiotic stress responses[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gibberellin A3. CAS No. 77-06-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-N1964. | |
| Gibberellin A1 | Gibberellin A1 is a kind of plant hormones. Gibberellin A1 is a growth-promoting acids isolated from immature seed of Phaseolus multiflorus[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 545-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N7443. | |
| Gibberellins A4/A7 | Gibberellins A4/A7 induces stimulation of tracheid production in the terminal shoot of intact plants is mediated through an increase in the IAA level in the cambial region[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GA4+7. CAS No. 8030-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg. Product ID: HY-139351. | |
| Gigantol | Gigantol is an orally active bibenzyl compound. Gigantol targets MYC to promote its ubiquitin-proteasomal degradation and inhibit the growth of lung cancer cells. Gigantol exerts anti-lung cancer activity by inducing ferroptosis (Ferroptosis) via the SLC7A11-GPX4 axis. Gigantol restores the sensitivity of mcr-harboring multidrug-resistant bacteria to colistin. Gigantol ameliorates carbon tetrachloride-induced liver injury by inhibiting the activation of the JNK/cPLA2/12-LOX inflammatory pathway. Gigantol promotes cholesterol metabolism and progesterone biosynthesis in Leydig cells. Gigantol can be used in studies related to diseases such as lung cancer, multidrug-resistant Gram-negative bacterial infections, and acute liver injury[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83088-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N10549. | |
| Gilteritinib | Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215. CAS No. 1254053-43-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12432. | |
| Gilteritinib-d8 | Gilteritinib-d8 is deuterium labeled Gilteritinib. Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215-d8. CAS No. 2377109-74-3. Pack Sizes: 1 mg. Product ID: HY-12432S1. | |
| Gilteritinib hemifumarate | Gilteritinib (ASP2215) hemifumarate is a potent and ATP-competitive FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215 hemifumarate. CAS No. 1254053-84-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12432A. | |
| Gilteritinib (Standard) | Gilteritinib (Standard) is the analytical standard of Gilteritinib. This product is intended for research and analytical applications. Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215 (Standard). CAS No. 1254053-43-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12432R. | |
| Gilvetmab | Gilvetmab is a potent caninized anti-PD-1 monoclonal antibody. Gilvetmab blocks the interaction between PD-1 and its ligand PD-L1/L2. Gilvetmab can be used in malignant melanoma and mast cell tumor research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1808081-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99641. | |
| Gimeracil | Gimeracil, a component of an oral fluoropyrimidine derivative S-1, inhibits DNA DSB repair and is a potent inhibitor of DPYD (dihydropyrimidine dehydrogenase, DPD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gimestat. CAS No. 103766-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g. Product ID: HY-17469. | |
| Gimistotug | HY-P990919 is an TNFRSF4-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BGB-A445. CAS No. 2768487-95-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990919. | |
| Ginisortamab | Ginisortamab (UCB6114) is a fully human IgG4P anti Gremlin-1 monoclonal antibody, with mean IC50 values of 8.2 nM and 9 nM against human and mouse gremlin-1, respectivly. Ginisortamab inhibits gremlin-1 antagonism of BMP signaling pathways. Ginisortamab has the potential for the research of gastrointestinal (GI) tumors[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCB6114. CAS No. 2390147-17-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99643. | |
| Ginkgetin | Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC50 of 5.92 μΜ[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 481-46-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0889. | |
| Ginkgolic acid | Ginkgolic Acid is a natural compound that inhibits SUMOylation with an IC50 of 3.0 μM in in vitro assay. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ginkgolic acid I. CAS No. 22910-60-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0077. | |
| Ginkgolic Acid (C13:0) | Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC50: 2.49 μM). Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC50: 2.40 μM)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ginkgolic acid (13:0); Ginkgoneolic Acid; 6-Tridecylsalicylic acid. CAS No. 20261-38-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0078. | |
| Ginkgolic acid C17:1 | Ginkgolic acid C17:1 is a fatty acid synthase (FAS) inhibitor with an IC50 of 10.5 μM. Ginkgolic acid C17:1 shows anti-tumor activity by inhibiting the phosphorylation of STAT3 and inducing apoptosis. Ginkgolic acid C17:1 can block the interaction between S-RBD and ACE2, and has anti-SARS-CoV-2-S pseudovirus activity. Ginkgolic acid C17:1 inhibits the biofilm formation of enterohemorrhagic Escherichia coli and Staphylococcus aureus[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 111047-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N2116. | |
| Ginkgolide A | Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BN-52020. CAS No. 15291-75-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0355. | |
| Ginkgolide B | Ginkgolide B (BN-52021), a terpene lactone, is a potent platelet activating factor antagonist. Ginkgolide B protects endothelial cells via the activation of PXR from injuries induced by xeno- and endobiotics. Ginkgolide B can pass through the brain-blood barrier. Ginkgolide B has anti-oxidant, anti-inflammatory, anti-tumor, and anti-apoptotic activity. Ginkgolide B has marked neuroprotective effects against ischemia-induced impairments[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BN-52021. CAS No. 15291-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-N0784. | |
| Ginkgolide K | Ginkgolide K, isolated from Ginkgo biloba, induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. Ginkgolide K possesses neuroprotective activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 153355-70-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N4176. | |
| Ginsenoside C-K | Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ginsenoside compound K; Ginsenoside K. CAS No. 39262-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0904. | |
| Ginsenoside F1 | Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 20(S)-Ginsenoside F1. CAS No. 53963-43-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0598. | |
| Ginsenoside Ra1 | Ginsenoside Ra1 is a component from ginseng, inhibits protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation[1]. Uses: Scientific research. Category: Natural products. CAS No. 83459-41-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2506. | |
| Ginsenoside Rb1 | Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gypenoside III. CAS No. 41753-43-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0039. | |
| Ginsenoside Rb2 | Ginsenoside Rb2 is one of the main bioactive components of ginseng extracts. Rb2 can upregulate GPR120 gene expression. Ginsenoside Rb2 has antiviral effects. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ginsenoside C. CAS No. 11021-13-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0040. | |
| Ginsenoside Rb3 | Ginsenoside Rb3 is extracted from steamed Panax ginseng C. A. Meyer. Ginsenoside Rb3 exhibits inhibitory effect on TNFα-induced NF-κB transcriptional activity with an IC50 of 8.2 μM in 293T cell lines. Ginsenoside Rb3 also inhibits the induction of COX-2 and iNOS mRNA. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gypenoside IV. CAS No. 68406-26-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0041. | |
| Ginsenoside Rc | Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA)-mediated ion channel currents (IGABA). Ginsenoside Rc inhibits the expression of TNF-α and IL-1β. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Panaxoside Rc. CAS No. 11021-14-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N0042. | |
| Ginsenoside Re | Ginsenoside Re (Ginsenoside B2) is an extract from Panax notoginseng. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ginsenoside B2; Panaxoside Re; Sanchinoside Re. CAS No. 52286-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0044. | |
| Ginsenoside Rf | Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Panaxoside Rf. CAS No. 52286-58-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0601. | |
| Ginsenoside Rg1 | Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Panaxoside A; Panaxoside Rg1. CAS No. 22427-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0045. | |
| Ginsenoside Rh2 | Ginsenoside Rh2 (20(S)-Ginsenoside Rh2) induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 20(S)-Ginsenoside Rh2; 20(S)-Rh2. CAS No. 78214-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0605. | |
| Ginsenoside Rk1 | Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures[1].Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB[2].Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis[1].Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 494753-69-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-N2515. | |
| Ginsenoside Rk3 | Ginsenoside Rk3 is present in the roots Panax ginseng herbs. Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 364779-15-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0906. | |
| Gintemetostat | Gintemetostat (KTX-1001) is an orally active, highly specific NSD2/MMSET histone methyltransferase inhibitor with human NSD2 IC50 values ranging 0.460-2.17 nM and NSD2 SET domain IC50 of 2.32 nM and Kd values ranging 6.3-70.4 nM[1][4].Gintemetostat reduces H3K36me2 levels, impairs multiple myeloma cell adhesion and colony formation, enhances cytotoxicity, boosts T-cell activation, and sensitizes resistant multiple myeloma cells to other agents[1][2][6].Gintemetostat can be used for the research of multiple myeloma and relapsed and refractory multiple myeloma[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KTX-1001. CAS No. 2604513-16-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154812. | |
| GIP (3-42), human | GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802086-25-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2542. | |
| GIP, human | GIP, human, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gastric Inhibitory Peptide (GIP), human. CAS No. 100040-31-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0276. | |
| GIP (mouse) | GIP (Gastric inhibitory polypeptide) (mouse) is a gastrointestinal hormone that is secreted by the intestinal K cells, and also expressed in and secreted from pancreatic islets. GIP (mouse) promotes insulin secretion from pancreatic β cells via the G-protein-coupled GIP receptor (GIPR). GIP (mouse) promotes pancreatic β cell proliferation and inhibits apoptosis. GIP (mouse) also exerts direct lipogenic effects on adipose tissue[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse). CAS No. 181591-59-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10735. | |
| Giredestrant | Giredestrant (GDC-9545), a non-steroidal estrogen receptor (ER) ligand, is an orally active and selective ER antagonist. Giredestrant potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-9545; RG6171. CAS No. 1953133-47-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109176. | |
| Girentuximab | Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G250; cG250. CAS No. 916138-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99023. | |
| Girinimbine | Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Girinimbin. CAS No. 23095-44-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N9488. | |
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