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Fmoc-NH-PEG8-CH2COOH
Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG8-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 868594-52-9. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g; 25 g. Product ID: HY-133063.
Fmoc-N-Me-Arg(Pbf)-OH
Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 913733-27-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-137002.
Fmoc-N-Me-Ser(tBu)-OH
Fmoc-N-Me-Ser(tBu)-OH is a serine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 197632-77-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W013749.
Fmoc-N-Me-Thr(tBu)-OH
Fmoc-N-Me-Thr(tBu)-OH is a threonine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 117106-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W013745.
Fmoc-NMe-Val-Val-Dil-Dap-OH
Fmoc-NMe-Val-Val-Dil-Dap-OH is an intermediate for preparing drug-linker conjugate MC-MMAF, which can be used for synthesis of ADC molecule[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1352202-13-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W250408.
Fmoc-OSu
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-(Fmoc-oxy)succinimide. CAS No. 82911-69-1. Pack Sizes: 25 g. Product ID: HY-79647.
Fmoc-PEA
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329223-23-6. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-128929.
Fmoc-PEG5-NHS ester
Fmoc-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1402080-11-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-122459.
Fmoc-Pen(Trt)-OH
Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 201531-88-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W008876.
Fmoc-Phe(CF2PO3)-OH
Fmoc-Phe(CF2PO3)-OH is a phenylalanine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160751-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W141821.
Fmoc-Phe-OH
Fmoc-Phe-OH is a phenylalanine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 35661-40-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 250 g; 500 g. Product ID: HY-79131.
Fmoc-Pra-OH
Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative[1]. Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 198561-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W011210.
Fmoc-Pro-OH
Fmoc-Pro-OH is a proline derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71989-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g. Product ID: HY-W013780.
Fmoc-(S)-2-(4-pentenyl)Ala-OH
Fmoc-(S)-2-(4-pentenyl) Ala-OH is an Fmoc-protected unnatural amino acid. Fmoc-(S)-2-(4-pentenyl) Ala-OH can be used for polypeptide synthesis, such as NYAD-13 (HY-P10834)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 288617-73-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-W004864.
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH
Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH (Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH) is a protected glycosylated amino acid and Tn antigen. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH serves as a building block in the solid-phase synthesis of Tn-based cancer vaccine constructs. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH supports solid-phase peptide synthesis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH. CAS No. 120173-57-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104004.
Fmoc-Ser-OtBu
Fmoc-Ser-OtBu is a serine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 110797-35-8. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g; 5 g; 25 g. Product ID: HY-22297.
Fmoc-Ser(tBu)-OH
Fmoc-Ser(tBu)-OH is a serine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71989-33-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g. Product ID: HY-W007941.
Fmoc-Ser(Trt)-OH
Fmoc-Ser(Trt)-OH is a serine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 111061-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W010734.
Fmoc-Thr(tBu)-OH
Fmoc-Thr(tBu)-OH is a threonine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71989-35-0. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g. Product ID: HY-W007706.
Fmoc-Trp(Boc)-OH
Fmoc-Trp(Boc)-OH (Fmoc-L-Trp(Boc)-OH) is an amino acid derivative with protective groups. Fmoc-Trp(Boc)-OH can self-assemble into stable and pH-responsive spherical nanoparticles, which can load and release bioactive molecules, with good biocompatibility and high cell uptake rate. Fmoc-Trp(Boc)-OH can be used in research on drug delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fmoc-L-Trp(Boc)-OH. CAS No. 143824-78-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g. Product ID: HY-W008034.
Fmoc-Trp(Me)-OH
Fmoc-Trp(Me)-OH is an amino acid derivative. Fmoc-Trp(Me)-OH is formed by introducing a methyl group onto the nitrogen atom (N-1 position) of the indole ring of tryptophan (Trp) and protecting the amino group with Fmoc (9-fluorenylmethyloxycarbonyl). Fmoc-Trp(Me)-OH can be used in the synthesis of proteins or peptides[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334509-86-2. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W048688.
Fmoc-Tyr(H2PO3)-OH
Fmoc-Tyr(H2PO3)-OH is a tyrosine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147762-53-6. Pack Sizes: 1 g; 5 g. Product ID: HY-W008908.
Fmoc-Tyr(tBu)-OH
Fmoc-Tyr(tBu)-OH is a tyrosine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71989-38-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g. Product ID: HY-W008016.
Fmoc-Val-Ala-aminomethyl acetate
Fmoc-Val-Ala-aminomethyl acetate (Compound 58b) is an ADC Linker, and can be used for synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2505045-86-1. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-156813.
Fmoc-Val-Ala-PAB-PNP
Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1394238-92-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-136136.
Fmoc-Val-Cit-PAB
Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker. Uses: Scientific research. Category: Signaling pathways. CAS No. 159858-22-7. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-19318.
Fmoc-Val-Cit-PAB-PNP
Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 863971-53-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g; 10 g. Product ID: HY-41189.
FN-1501
FN-1501 is a potent inhibitor of FLT3 and CDK, with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively. FN-1501 has anticancer activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LT-171-861. CAS No. 1429515-59-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111361.
Folic acid
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency[1][2][3][4]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Vitamin B9; Vitamin M. CAS No. 59-30-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-16637.
Folic acid-d2
Folic acid-d2 (Vitamin B9-d2) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B9-d2; Vitamin M-d2. CAS No. 69022-87-3. Pack Sizes: 5 mg. Product ID: HY-16637S.
Folic acid-d4
Folic acid-d4 is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B9-d4; Vitamin M-d4. CAS No. 171777-72-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-16637S1.
Folic acid disodium
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·105 g/s[1]. Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B9 disodium; Vitamin M disodium. CAS No. 29704-76-5. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-16637D.
Folic acid (Standard)
Folic acid (Standard) is the analytical standard of Folic acid. This product is intended for research and analytical applications. Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B9 (Standard); Vitamin M (Standard). CAS No. 59-30-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-16637R.
Foliglurax monohydrochloride
Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM[1]. Antiparkinsonian effect[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PXT002331 monohydrochloride. CAS No. 2133294-96-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108703A.
Folinic acid
Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: leucovorin. CAS No. 58-05-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17556.
Folinic acid calcium
Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Leucovorin calcium; Calcium folinate. CAS No. 1492-18-8. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-13664.
Folinic acid calcium salt pentahydrate
Folinic acid calcium salt pentahydrate (Leucovorin calcium salt pentahydrate) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Leucovorin calcium salt pentahydrate. CAS No. 6035-45-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0080.
Folinic acid (Standard)
Folinic acid (Standard) is the analytical standard of Folinic acid. This product is intended for research and analytical applications. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: leucovorin (Standard). CAS No. 58-05-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17556R.
Folitixorin
Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,10-Methylenetetrafolate; ANX-510 free acid. CAS No. 3432-99-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14769.
Fomc-Gly-Gly-Phe-Gly-OH
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1817857-75-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-P4192.
Fomepizole
Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Methylpyrazole. CAS No. 7554-65-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0876.
Fomivirsen
Fomivirsen (ISIS-2922) is an antisense phosphorothioate oligonucleotide. Fomivirsen is an antiviral reagent used in research on cytomegalovirus (CMV) retinitis. Fomivirsen binds to and degrades the mRNA of CMV immediate-early 2 protein, thereby inhibiting viral proliferation. Fomivirsen can be used in research related to cytomegalovirus retinitis and cytomegalovirus diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS-2922. CAS No. 144245-52-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-112958.
Fomivirsen sodium
Fomivirsen (ISIS-2922) sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen sodium is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein, thus inhibiting virus proliferation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS-2922 sodium. CAS No. 160369-77-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109528.
Fondaparinux sodium
Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fondaparin sodium; SR-90107A. CAS No. 114870-03-0. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0597.
Fontolizumab
Fontolizumab (HuZAF) is a humanized monoclonal anti-IFN-gamma antibody. Fontolizumab is an immunosuppressive agent. Fontolizumab can be used in research of Crohns disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HuZAF; Anti-Human IFNG Recombinant Antibody. CAS No. 326859-36-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99292.
Foralumab
Foralumab (NI-0401) is a potent, orally active human monoclonal antibody targeting the CD3. Foralumab modulates immune responses by human cells in NSG mice that were reconstituted with human hematopoietic stem cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NI-0401. CAS No. 946415-64-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99199.
Forchlorfenuron
Forchlorfenuron is plant growth regulator and cytokinin; can be used to increase fruit size of fruits, such as kiwi fruit and grapes. Uses: Scientific research. Category: Signaling pathways. CAS No. 68157-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B1841.
Foretinib
Foretinib is a multi-target tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XL880; GSK1363089; GSK089; EXEL-2880. CAS No. 849217-64-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10338.
Forimtamig
Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2?+?1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG-6234; RO-7425781. CAS No. 2649379-96-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991055.
Formaldehyde dehydrogenase, Pseudomonas sp
Formaldehyde dehydrogenase is a widely occuring enzyme that can catalyze S-hydroxymethylglutathione in the presence of NAD. Formaldehyde dehydrogenase detoxifies formaldehyde within cells through capturing and limiting it from reaching a toxic level. Formaldehyde dehydrogenase can be studied in research on M. tuberculosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9028-84-6. Pack Sizes: 5 U; 25 U. Product ID: HY-P2909.
Formamide (deionized)
Formamide deionized (Methanamide deionizde) is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions. Formamide deionized can also be used as a decalcifying agent for rat cardiac cells. Additionally, Formamide deionized is widely used as a solvent or chemical raw material for ion compounds, resins, and plasticizers[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methanamide (deionized); Formimidic acid (deionized). CAS No. 75-12-7. Pack Sizes: 100 mL; 500 mL. Product ID: HY-Y0842B.
Formate dehydrogenase
Formate dehydrogenase is a class of oxidoreductases widely distributed in bacteria, fungi, plants and animals. Formate dehydrogenase catalyzes the reversible conversion between formic acid and carbon dioxide, accompanied by redox reactions of the coenzyme NAD+/NADH or other electron carriers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9028-85-7. Pack Sizes: 50 U; 100 U. Product ID: HY-P2907.
Formic acid ammonium
Formic acid ammonium is the ammonium salt form of formic acid, which is an endogenous metabolite. Formic acid ammonium activates the nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling pathway in endothelial cells and inhibits calcium ion influx in vascular smooth muscle cells, resulting in vasomotor relaxation. Formic acid ammonium inhibits cytochrome C oxidase (CcO) and disrupts the electron transport chain, leading to ATP depletion. Formic acid ammonium can be used as a feed additive, which can lower the feed pH value, inhibit the growth of microorganisms (such as Escherichia coli, Salmonella), and extend the shelf life of the feed[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ammonium formate. CAS No. 540-69-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 g; 100 g; 500 g. Product ID: HY-Y0488A.
Formiminoglutamic acid
Formiminoglutamic acid, an endogenous metabolite, could be an index of folic-acid deficiency[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 816-90-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-129398.
Formononetin
Formononetin is a potent FGFR2 inhibitor with an IC50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Biochanin B; Flavosil; Formononetol. CAS No. 485-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N0183.
Formosanin C
Formosanin C is a diosgenin saponin with multiple biological activities. Formosanin C possesses multiple anti-tumor mechanisms, including inducing apoptosis and autophagy, blocking the cell cycle, inhibiting metastasis and inducing ferroptosis. Formosanin C can inhibit the NF-κB signaling pathway to exert anti-inflammatory effects, and enhance the activity of immune cells. Formosanin C exhibits the inhibiting effect against C. albicans. Formosanin C can be used for the study of anti-inflammation, antifungal anti and anti-cancer (including lung cancer, liver cancer, breast cancer and colorectal cancer, etc.)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 50773-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2389.
Formoterol-1
Formoterol ((±)Formoterol) is an orally active β2-selective agonist. Formoterol potently relaxes the peripheral airways through stimulating the beta 2-adrenoceptors selectively as is the case in the central airways and that it significantly inhibits IgE-mediated slow reactive substance of anaphylaxis (SRS-A) release through beta-adrenoceptor stimulation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)Formoterol. CAS No. 73573-87-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0010B.
Formoterol fumarate
Formoterol fumarate ((±)Formoterol fumarate) is a selective β2-adrenoceptor agonist. Formoterol fumarate is at least as β2-adrenoceptor selective as Salbutamol (HY-B1037) and Terbutaline (HY-B0802A). Formoterol fumarate abolishs the contraction induced by Acetylcholine in bronchioles. Formoterol fumarate can be used for the research of chronic obstructive pulmonary disease and bronchial asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)Formoterol fumarate. CAS No. 43229-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0010.
Formoterol hemifumarate hydrate
Formoterol hemifumarate hydrate is a selective, long-acting beta 2-adrenoceptor agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD). Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 183814-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108901.
Forodesine
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCX-1777; Immucillin-H. CAS No. 209799-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16210.
Forodesine hydrochloride
Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCX-1777 hydrochloride; Immucillin-H hydrochloride. CAS No. 284490-13-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16209.
Forskolin
Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase[1]. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy[4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Coleonol; Colforsin; HL 362. CAS No. 66575-29-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15371.
Forskolin (Standard)
Forskolin (Standard) is the analytical standard of Forskolin. This product is intended for research and analytical applications. Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase[1]. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy[4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Coleonol (Standard); Colforsin (Standard); HL 362 (Standard). CAS No. 66575-29-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15371R.
Forsythoside B
Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB. Uses: Scientific research. Category: Signaling pathways. CAS No. 81525-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0029.
Fosamprenavir
Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amprenavir phosphate; GW 433908. CAS No. 226700-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-78726.
Fosamprenavir Calcium Salt
Fosamprenavir Calcium Salt (GW433908G) is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir Calcium Salt is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir Calcium Salt can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GW433908G. CAS No. 226700-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17431.
Fosaprepitant dimeglumine
Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0517; L785298. CAS No. 265121-04-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14407A.
Fosbretabulin disodium
Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. Fosbretabulin disodium is the Combretastatin A4 proagent that selectively targets endothelial cells, induces regression of nascent tumour neovessels, reduces tumour blood flow and causes central tumour necrosis[1][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CA 4DP; CA 4P; Combretastatin A4 disodium phosphate. CAS No. 168555-66-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17449.
Foscarbidopa
Foscarbidopa (ABBV-951; Carbidopa 4-monophosphate) is an inhibitory prodrug targeting peripheral aromatic L-amino acid decarboxylase. Foscarbidopa is hydrolyzed into Carbidopa (HY-B0311) by phosphatases in vivo to suppress peripheral metabolism of levodopa and elevate brain delivery of levodopa. Foscarbidopa can be used for the research of Parkinsons disease and advanced Parkinsons disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABBV-951; Carbidopa 4-monophosphate. CAS No. 1907685-81-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109131.
Foscarnet sodium
Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Trisodium phosphonoformate; Phosphonoformic acid trisodium salt. CAS No. 63585-09-1. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg. Product ID: HY-B1318.