MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Erythromycin-13C,d3 | Erythromycin-13C,d3 is the 13C- and deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2378755-50-9. Pack Sizes: 1 mg. Product ID: HY-B0220S1. |  |
| Erythromycin A enol ether | Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 33396-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122207. | |
| Erythromycin lactobionate | Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research[3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3847-29-8. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-B0220A. | |
| Erythromycylamine | Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26116-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-W055872. | |
| Erythrosine B | Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Erythrosin extra bluish. CAS No. 16423-68-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-D0259. | |
| Erzotabart | Erzotabart is an IgG1-kappa, anti-CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1) Homo sapiens monoclonal antibody. Erzotabart shows antineoplastic activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GEN3014. CAS No. 2430792-01-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990037. | |
| ES9-17 | ES9-17 is an analog of ES9 (endosidin9), which is an inhibitor of clathrin heavy chain (CHC). ES9-17 is an inhibitor of clathrin-mediated endocytosis (CME), a major route for internalization of plasma membrane proteins and molecules from the extracellular environment in plants. ES9-17 inhibits the uptake of transferrin and FM4-64. ES9-17 also inhibits root growth of Arabidopsis seedings[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55854-43-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131683. | |
| ES 936 | ES 936 is a potent and specific NQO1 inhibitor. ES 936 inhibits the growth of MIA PaCa-2 and BxPC-3 cells, with IC50 values of 108 nM and 365 nM, respectively. ES936 significantly inhitbits the growth rate of MIA PaCa-2 xenograft tumors in mice. ES 936 can be used for the study of pancreatic cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 192820-78-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100367. | |
| Esaxerenone | Esaxerenone (CS-3150) is a highly potent and selective non-steroidal mineralocorticoid receptor antagonist[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CS-3150; XL-550. CAS No. 1632006-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100471. | |
| Eschweilenol C | Eschweilenol C is a selective Plasmodium falciparum growth inhibitor. Eschweilenol C disrupts haemoglobin metabolism, reduces haemozoin production, kills Plasmodium falciparum ring and trophozoite stages. Eschweilenol C can be used for the research of inflammatory disorders and malaria[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 211371-02-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N12352. | |
| Escin | Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6805-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-B2114. | |
| Escin IA | Escin IA is an oral LOXL2 inhibitor and EMT inhibitor, with selectivity for LOXL2-expressing cells. Escin IA suppresses invasion, migration, and metastasis of breast cancer cells, and acts as the primary anti-TNBC metastasis constituent of Aesculus chinensis Bunge fruit saponin fraction. Escin IA can be used for the research of triple-negative breast cancer, acute inflammation, and ethanol-induced gastric mucosal lesions[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123748-68-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N0554. | |
| Escin IB | Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26339-90-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0555. | |
| Escitalopram | Escitalopram ((S)-Citalopram), the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram has ?30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram is an antidepressant for the research of major depression[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Citalopram; (S)-(+)-Citalopram. CAS No. 128196-01-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14258. | |
| Escitalopram oxalate | Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ?30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Citalopram oxalate; (S)-(+)-Citalopram oxalate. CAS No. 219861-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14258A. | |
| (E)-Selinexor | (E)-Selinexor ((E)-KPT-330) is the E-isomer of Selinexor (HY-17536). Selinexor is the selective, orally active CRM1 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-KPT-330. CAS No. 1421923-86-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17536A. | |
| ESI-05 | ESI-05 is a specific exchange proteins directly activated by cAMP 2 (EPAC2) inhibitor. ESI-05 inhibits cAMP-mediated EPAC2 GEF activity with an IC50 of 0.43 μM. ESI-05 can be used for the research of diabetes, insulin secretion and neurological disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 116966. CAS No. 5184-64-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117656. | |
| ESI-08 | ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC50 of 8.4 μM) activity. ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 301177-43-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136172. | |
| ESI-09 | ESI-09 is a novel noncyclic nucleotide EPAC antagonist with IC50 values of 3.2 and 1.4 μM for EPAC1 and EPAC2, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 263707-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-16704. | |
| Eslicarbazepine | Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIA 2-194. CAS No. 104746-04-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114703. | |
| Eslicarbazepine acetate | Eslicarbazepine acetate (BIA 2-093), an antiepileptic agent, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIA 2-093. CAS No. 236395-14-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0703. | |
| Esmolol hydrochloride | Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptor. Esmolol hydrochloride attenuates post resuscitation myocardial dysfunction. Esmolol hydrochloride improves diabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81161-17-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1392. | |
| Esomeprazole | Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Omeprazole; (-)-Omeprazole. CAS No. 119141-88-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17021. | |
| Esomeprazole magnesium trihydrate | Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent and orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research[1][2]. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Omeprazole magnesium trihydrate; (-)-Omeprazole magnesium trihydrate. CAS No. 217087-09-7. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-17022. | |
| Esomeprazole potassium salt | Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole potassium salt has the potential for symptomatic gastroesophageal reflux disease research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Omeprazole potassium salt; (-)-Omeprazole potassium salt. CAS No. 161796-84-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-17021B. | |
| Esterase, pig liver | Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CESs. CAS No. 9016-18-6. Pack Sizes: 1 KU. Product ID: HY-P2831. | |
| Estetrol | Estetrol, an orally active estrogen synthesized exclusively during pregnancy by the human fetal liver, is a selective nuclear estrogen receptor modulator. Estetrol binds ERα as well as ERβ (with a fourfold lower affinity). Estetrol increases eNOS expression/activity and NO synthesis in endothelial cells. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on the breast. Estetrol can be used in contraception and menopausal hormone research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15183-37-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15731. | |
| Estradiol | Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol. CAS No. 50-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-B0141. | |
| Estradiol 3-glucuronide | Estradiol 3-glucuronide is an estrogen metabolite, which is a glucuronide conjugate formed from Estradiol (HY-B0141) via catalysis by uridine diphosphate glucuronosyltransferases in tissues such as the liver. Estradiol 3-glucuronide is a potent substrate of Mrp2, with an S50 value of 55.7 μM. Estradiol 3-glucuronide achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15270-30-1. Pack Sizes: 500 μg; 1 mg. Product ID: HY-W585842. | |
| Estradiol 3-methyl ether | Estradiol 3-methyl ether (EDME) is a highly selective TRPML1 ion channel antagonist and microtubule (microtubule) depolymerizing agent, with IC50 values of 0.22 μM and 3.8 μM against TRPML1 and TRPML2, respectively; it shows no activity against TRPML3. Estradiol 3-methyl ether induces the disruption of cytoplasmic microtubule networks in mammalian cells, with an EC50 of 9 μM. Independent of estrogen receptors, Estradiol 3-methyl ether blocks autophagy (autophagy), TFEB nuclear translocation, and inhibits the migration and invasion of triple-negative breast cancer cells by suppressing TRPML1. Estradiol 3-methyl ether is applicable for relevant research on triple-negative breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-O-Methyl estradiol; 17β-Estradiol 3-methyl ether; 3-Methoxyestradiol. CAS No. 1035-77-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W008581. | |
| Estradiol benzoate | Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate. CAS No. 50-50-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-B1192. | |
| Estradiol-d2 | Estradiol-d2 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-Estradiol-d2; 17β-Estradiol-d2; 17β-Oestradiol-d2. CAS No. 53866-33-4. Pack Sizes: 1 mg. Product ID: HY-B0141S3. | |
| Estradiol-d4 | Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-Estradiol-d4; 17β-Estradiol-d4; 17β-Oestradiol-d4. CAS No. 66789-03-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-B0141S1. | |
| Estradiol (Standard) | Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-Estradiol (Standard); E2 (Standard); 17β-Estradiol (Standard); 17β-Oestradiol (Standard). CAS No. 50-28-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0141R. | |
| Estragole-d4 | Estragole-d4 is deuterated labeled Estragole (HY-N5060). Estragole (4-Allylanisole) is a relatively nontoxic volatile terpenoid ether and major component of the essential oil from many plants. Estragole significantly triggers Apoptosis, suppresses LPS-induced intracellular ROS production. Estragole activats Nrf-2 and regulates NF-κB. Estragole has anti-toxoplasma, anti-inflammatory, anti-edema, antioxidant and immunomodulatory properties. Estragole blocks DRG neuron excitability. Estragole has improves gastric ulcer activity[1][2][3][4][5][6][7][8][9][10][11][12][13]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Allylanisole-d4. CAS No. 1335401-40-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N5060S. | |
| Estramustine | Estramustine, an estradiol analog, is an orally active antimicrotubule chemotherapy agent. Estramustine depolymerises microtubules by binding to microtubule associated proteins (MAPs) and/or to tubulin. Estramustine can interfere mitosis, trigger cell death and induce apoptosis, which can be used for the research of cancer like prostate cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2998-57-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103711. | |
| Estriol | Estriol (Oestriol), an orally active estrogen, is a ERα and ERβ agonist. Estriol is a potent GPR30 antagonist in estrogen receptor-negative breast cancer cells. Estriol can ameliorate disease severity through immunomodulatory mechanisms that decrease tissue inflammation. Estriol has powerful proconvulsant effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oestriol. CAS No. 50-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0412. | |
| Estriol 3-glucuronide sodium salt | Estriol 3-glucuronide (Estriol 3-β-D-Glucuronide) sodium salt is a metabolite of Estriol. Estriol 3-glucuronide sodium salt competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide (4Mu-GlcU). Estriol 3-glucuronide sodium salt is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Estriol 3-β-D-Glucuronide sodium salt. CAS No. 15087-06-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-137321. | |
| Estriol-d3 | Estriol-d3 is the deuterium labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 79037-36-8. Pack Sizes: 1 mg. Product ID: HY-B0412S2. | |
| Estriol (Standard) | Estriol (Standard) is the analytical standard of Estriol. This product is intended for research and analytical applications. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oestriol (Standard). CAS No. 50-27-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0412R. | |
| Estrogen receptor-agonist-1 | Estrogen receptor-agonist-1 (compound 4e) is a estrogen receptor (ER) agonist that binds to ERα with high affinity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 263717-32-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-W1006471. | |
| Estrone | Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E1; Oestrone. CAS No. 53-16-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0234. | |
| Estrone-13C3 | Estrone-13C3 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E1-13C3; Oestrone-13C3. CAS No. 1241684-29-6. Pack Sizes: 5 mg; 1 mg. Product ID: HY-B0234S. | |
| Estrone 3-glucuronide sodium | Estrone 3-glucuronide sodium is a metabolite of 17-Estradiol[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15087-01-1. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008917. | |
| Estrone-d4 | Estrone-d4 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E1-d4; Oestrone-d4. CAS No. 53866-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0234S2. | |
| Estrone sulfate sodium | Estrone sulfate sodium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate sodium is also a substrate of the OATP1B3 transporter. Estrone sulfate sodium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate sodium is applicable to breast cancer-related research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 438-67-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113293B. | |
| Esuprone | Esuprone is a brain-penetrant, orally active and selective MAO A inhibitor with an IC50 of 7.3 nM. Esuprone can be used for neurological research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 91406-11-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-106770. | |
| Et-29 | Et-29 is a potent and selective SIRT5 inhibitor (Ki=40 nM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NRD167. CAS No. 2166487-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-145651. | |
| Etalanetug | Etalanetug (E2814) is a humanized high-affinity IgG1 antibody that targets tau protein and can cross the blood-brain barrier. Etalanetug inhibits the spread of pathological tau protein through high-affinity binding to the microtubule-binding region (MTBR). Etalanetug can be used in research related to Alzheimer's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E2814. CAS No. 2690265-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990995. | |
| Etalocib | Etalocib (LY293111), an orally active leukotriene B4 receptor antagonist, inhibits the binding of [3H]LTB4, with a Ki of 25 nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. Etalocib (LY293111) induces apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY293111; VML 295. CAS No. 161172-51-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13628. | |
| Etamivan (Standard) | Etamivan (Ethamivan; N,N-Diethylvanillamide) (Standard) is the analytical standard of Etamivan (HY-B1096). This product is intended for research and analytical applications. Etamivan is an orally active respiratory stimulant. Ethamivan regulates breathing patterns by directly stimulating the medullary respiratory center, prioritizing increased breathing depth rather than frequency. Etamivan can be used in the research of barbiturate overdose and chronic obstructive pulmonary disease. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethamivan (Standard); N,N-Diethylvanillamide (Standard). CAS No. 304-84-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1096R. | |
| Etanercept | Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 185243-69-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-108847. | |
| Etaracizumab | Etaracizumab (LM 609) is an αvβ3 integrin IgG mAb. Etaracizumab is developed to target αvβ3+ cancer cells via NK cell-mediated cytotoxicity. Etaracizumab sterically hinders access of large ligands to the RGD-binding pocket, without obstructing it. Etaracizumab decreases p-Akt in vitro. Etaracizumab can decrease cancer proliferation and invasion. Etaracizumab induces tumor cell apoptosis, and inhibition ofαvβ3-mediated cell adhesion, endothelial cell migration and osteoclast-mediated bone resorption. Etaracizumab can be studied in anti-tumor research against cancers such as ovarian cancer, metastatic melanoma as well as advanced solid tumors. Recommend Isotype Control: Human IgG1 kappa, Isotype Control (HY-P99001)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LM609; MEDI-522. CAS No. 892553-42-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99291. | |
| Etavopivat | Etavopivat is a potent, selective, and orally active erythrocyte pyruvate kinase (PKR) activator. Etavopivat has potent antisickling effects that can be used in studies of sickle cell disease and other haemoglobinopathies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FT-4202. CAS No. 2245053-57-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139573. | |
| ETC-159 | ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. ETC-159 inhibits β-catenin reporter activity with an IC50 of 2.9 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ETC-1922159. CAS No. 1638250-96-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18988. | |
| Etelcalcetide hydrochloride | Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride. CAS No. 1334237-71-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1955A. | |
| Etentamig | Etentamig is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. Etentamig can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABBV-383; TNB 383B. CAS No. 2490552-52-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P990785. | |
| Eteplirsen | Eteplirsen (AVI 4658) is a synthetic antisense oligonucleotide. Eteplirsen can be used for Duchenne muscular dystrophy research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AVI 4658. CAS No. 1173755-55-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108753. | |
| (E)-tert-Butyldimethyl((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-1-yl)oxy)silane | (E)-tert-Butyldimethyl((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-1-yl)oxy)silane is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 480425-30-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W102301. | |
| Etesevimab | Etesevimab (JS016) is a recombinant neutralizing human IgG1 anti-SARS-CoV-2 monoclonal antibody[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CB 6; JS016. CAS No. 2423948-94-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99347. | |
| ETH 157 | ETH 157 is a neutral sodium-selective carrier. ETH 157 exhibits sufficient Na+/K+ selectivity and enhanced Na+/Ca2+ selectivity, making it suitable for the detection of extracellular Na+ activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 61595-77-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137172. | |
| Ethacizine hydrochloride | Ethacizine hydrochloride (Ethacizin; NIK-244) is a longer-lasting Class Ic antiarrhythmic agent than Flecainide[1]. Ethacizine hydrochloride (Ethacizin; NIK-244) inhibits the depolarizing current responsible for the intraatrial and His-Purkinje-ventricular conduction[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethacizin; NIK-244. CAS No. 57530-40-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135121. | |
| Ethacrynic acid | Ethacrynic acid has anti-inflammatory and anticancer activity. Ethacrynic acid is an orally active diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferase (GSTs) and Wnt signaling pathways. Ethacrynic acid is a radiosensitizer. Ethacrynic acid can inhibit airway smooth muscle (ASM) contraction in mice. Ethacrynic acid can increase the outflow of aqueous humor from the eye for the study of glaucoma[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Etacrynic acid. CAS No. 58-54-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1640. | |
| Ethacrynic acid (Standard) | Ethacrynic acid (Standard) is the analytical standard of Ethacrynic acid. This product is intended for research and analytical applications. Ethacrynic acid (Etacrynic acid) is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Etacrynic acid (Standard). CAS No. 58-54-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1640R. | |
| Ethambutol | Ethambutol is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. Ethambutol can be used to establish animal models of hyperuricemia and optic neuropathy. Uses: Scientific research. Category: Induced disease models products. CAS No. 74-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0535. | |
| Ethambutol-d4 | Ethambutol-d4 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Emb-d4. CAS No. 1129526-19-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0535S. | |
| Ethambutol dihydrochloride | Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. Ethambutol dihydrochloride can be used to establish animal models of hyperuricemia and optic neuropathy. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Emb dihydrochloride. CAS No. 1070-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0535A. | |
| Ethanolamine hydrochloride | Ethanolamine hydrochloride, is an organic compound used in various industrial applications. It is a white or colorless solid that is soluble in water and has a faint odor. One of the major uses of Ethanolamine hydrochloride is in the production of detergents and surfactants. Used as a raw material in the manufacture of compounds such as ethylenediaminetetraacetic acid (EDTA) and diethanolamine, which are commonly used in household and industrial cleaning products. Ethanolamine hydrochloride is also used in the synthesis of pharmaceuticals, agrochemicals and rubber processing agents. It acts as a buffer in certain chemical reactions, helping to adjust pH and maintain stability. Ethanolamine hydrochloride can be used for gas purification and metal corrosion inhibitor. Its ability to react with acid gases such as carbon dioxide and sulfur dioxide makes it useful for removing impurities from natural gas and other industrial gases. Overall, Ethanolamine hydrochloride is a multifunctional compound with many potential industrial applications. Its ability to act as a buffer, chelating agent, and corrosion inhibitor makes it an important tool in a variety of industries. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Aminoethanol hydrochloride. CAS No. 2002-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g. Product ID: HY-W035903. | |
| Ethaverine hydrochloride | Ethaverine hydrochloride, a derivative of papaverine, inhibits cardiac L-type calcium channel. Ethaverine hydrochloride is a peripheral vasodilator and antispasmodic agent. Ethaverine hydrochloride can be used for research of peripheral vascular disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 985-13-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-B1440. | |
| EthD bromide | EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EtBr; Homidium bromide. CAS No. 1239-45-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-D0021. | |
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