MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| EB-47 dihydrochloride | EB-47 dihydrochloride, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM. EB-47 mimics the substrate NAD+?and extends from the nicotinamide to the adenosine subsite[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1190332-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108631. |  |
| Ebastine | Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LAS-W 090; RP64305. CAS No. 90729-43-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0674. | |
| (E)-β-Farnesene | (E)-β-Farnesene (trans-β-Farnesene) is an aphid alarm pheromone, which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene shows good binding score with a value of -30.64 kcal/mol to the CDK2 receptor. (E)-β-Farnesene also exhibits good affinity to odorant-binding protein 3 (OBP3). (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-β-Farnesene. CAS No. 18794-84-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-N7364. | |
| Ebio1 | Ebio1 is a selective voltage-gated potassium channel KCNQ2 activator. Ebio1 activates KCNQ2 by generating an extended channel gate with greater conductance at a saturation voltage (+50 mV)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 339287-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157485. | |
| Eblasakimab | Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASLAN004; CSL-334; MK-6105. CAS No. 2445460-16-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99870. | |
| EBNA1-IN-SC7 | EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 324022-08-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131236. | |
| EBOV/MARV-IN-1 | EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 μM, respectively) and low cytotoxicity (SI>100) in HeLa cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2479465-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137498. | |
| EBP-IN-1 | EBP-IN-1 is an orally active, blood-brain barrier-permeable inhibitor of emopamil binding protein (EBP). EBP-IN-1 has an IC50 of 8.2 μM against human ERG potassium channels (in CHO background). By inhibiting the sterol isomerase activity of EBP, EBP-IN-1 causes the accumulation of Zymostenol (HY-113345), and exhibits strong target binding in the brain after repeated administration in rodents. EBP-IN-1 also promotes oligodendrocyte formation in human cortical organoids and can be used in research related to multiple sclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3034437-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162351. | |
| Ebrasodebart | HY-P990917 is an TMEM219-targeting IgG4λ type human antibody, the recommed isotype control is Human IgG4 (S228P) lambda1, Isotype Control (HY-P99987)[1]. Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 2572467-73-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990917. | |
| Ebselen | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker[1][2]. Ebselen potently inhibits Mpro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM)[3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity[4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SPI-1005; PZ-51; CCG-39161. CAS No. 60940-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13750. | |
| EB-TCIP | EB-TCIP (BAK-04-212) is a proof-of-concept tool specifically designed for Ewing sarcoma research, serving as an EWSR1:FLI1 binder tagged with BCL6 and FKBP12F36V. EB-TCIP forms a ternary complex with the tagged fusion protein, specifically recruits EWSR1:FLI1 to BCL6-bound DNA loci, and induces rapid chromatin remodeling and relocalization. By mediating relocalization, EB-TCIP remodels the transcriptional machinery and activates the expression of BCL6 target genes that are originally repressed. EB-TCIP is used in studies related to novel epigenetic therapies for Ewing sarcoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAK-04-212. CAS No. 3114073-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-173364. | |
| Ebvaciclib | PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK), with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively. PF-06873600 has potential antineoplastic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06873600. CAS No. 2185857-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114177. | |
| EC1169 | EC1169 is a cytotoxic maytansinoid conjugate that specifically binds to prostate-specific membrane antigen (PSMA). EC1169 precisely delivers the maytansinoid B hydrazide payload to PSMA-positive cells to exert antitumor activity. EC1169 only inhibits the growth of PSMA-positive cells but has no effect on PSMA-negative cells, and enables complete recovery in mice bearing PSMA-positive tumors. EC1169 exhibits safety with no body weight loss or major organ damage induced. EC1169 is used in studies of prostate cancer and other PSMA-expressing malignancies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1610413-96-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-114256. | |
| EC144 | EC144 is a potent and selective inhibitor of heat shock protein 90 (Hsp90) with an IC50 of 1.1 nM. EC144 inhibits tumor growth and causes partial tumor regressions. EC144 has the potential for the research of cancer diseases[1]. EC144 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 911397-80-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13479. | |
| EC-17 disodium salt | EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 910661-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13615A. | |
| EC23 | EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AGN 190205; BASF-46928. CAS No. 104561-41-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-12309. | |
| EC330 | EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2016795-77-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100949. | |
| EC359 | EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions[1]. EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2012591-09-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120142. | |
| EC5026 | EC5026 (BPN-19186) is a first-in-class, non-opioid and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 shows efficacy for inflammatory and neuropathic pain[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BPN-19186. CAS No. 1809885-32-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135653. | |
| Ecdysone | Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Ecdysone. CAS No. 3604-87-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0179. | |
| eCF506 | eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native closed conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NXP900. CAS No. 1914078-41-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112096. | |
| Echinacoside | Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 82854-37-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0020. | |
| Echinomycin | Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Quinomycin A; NSC-13502. CAS No. 512-64-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-106101. | |
| ECI830 | ECI830 (CDK2-IN-37) is an orally active, ATP-competitive and highly selective CDK2 inhibitor. ECI830 shows high selectivity over other CDK family members. ECI830 can be used for the study of HR+/HER2- breast cancer and CCNE1-amplified tumors (such as ovarian cancer and lung cancer)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CDK2-IN-37. CAS No. 3054692-62-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170442. | |
| (E)-Cinnamoyl-coA | (E)-Cinnamoyl-coA ((E)-Cinnamoyl-coenzyme A) is a substrate of 2-hydroxyglutaryl-CoA dehydratase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-Cinnamoyl-coenzyme A. CAS No. 76109-04-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-E70237. | |
| Eciruciclib | Eciruciclib is an antineoplastic and potent cyclin dependent kinase (CDK) inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1868086-40-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145563. | |
| Ecleralimab | Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin (TSLP). Ecleralimab significantly attenuates allergen-induced airway responses and inflammation. Ecleralimab can be used for the study of inhaled asthma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CSJ-117; NVP-CSJ117. CAS No. 2415207-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99872. | |
| Ecliptasaponin D | Ecliptasaponin D is a triterpenoid glucoside isolated from Eclipta alba (L.) Hassk which is the aerial part of Eclipta prostrate. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant and immunomodulatory[1,2]. Uses: Scientific research. Category: Natural products. CAS No. 206756-04-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N2191. | |
| Ecnoglutide | Ecnoglutide (XW003) is a long-acting, cAMP-biased glucagon-like peptide 1 (GLP-1) receptor agonist. Ecnoglutide can be used for research of T2DM and obesity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XW003. CAS No. 2459531-73-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3366. | |
| E. coli Extract Polar | E. coli Extract Polar is a polar lipid extract of Escherichia coli containing phosphatidylethanolamine, phosphatidylglycerol, and cardiolipin for reconstitution of membrane proteins. Uses: Scientific research. Category: Signaling pathways. CAS No. 1240502-50-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-174940. | |
| Econazole | Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Econazol. CAS No. 27220-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B0885. | |
| Ecopipam hydrochloride | Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity[1][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCH 39166 hydrochloride. CAS No. 190133-94-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14689. | |
| Ecteinascidin 770 | Ecteinascidin 770 (ET-770) is a 1,2,3,4-tetrahydroisoquinoline alkaloid with potent anti-cancer activities; inhibits U373MG cells with an IC50 of 4.83 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ecteinascidine 770; Et-770. CAS No. 114899-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101191. | |
| Ectoine | Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96702-03-3. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-107784. | |
| Ectoine (Standard) | Ectoine (Standard) is the analytical standard of Ectoine. This product is intended for research and analytical applications. Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96702-03-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107784R. | |
| Eculizumab | Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in mice. Eculizumab can be used in hemolysis studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human C5, Humanized Antibody; h5G1.1. CAS No. 219685-50-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9914. | |
| Edaravone | Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCI-186. CAS No. 89-25-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g. Product ID: HY-B0099. | |
| Edaravone (Standard) | Edaravone (Standard) is the analytical standard of Edaravone. This product is intended for research and analytical applications. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCI-186 (Standard). CAS No. 89-25-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0099R. | |
| Edasalonexent | Edasalonexent (CAT-1004) is an orally bioavailable NF-κB inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAT-1004. CAS No. 1204317-86-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17630. | |
| Edecesertib | Edecesertib (GS-5718) is a selective, potent, orally active IRAK-4 inhibitor. Edecesertib has anti-inflammatory activity. Edecesertib can be used for rheumatoid arthritis (RA) and lupus erythematosus (LE) research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-5718. CAS No. 2408839-73-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147264. | |
| Edelfosine | Edelfosine (ET-18-OCH3) is an orally active lipid raft modulator and apoptosis inducer that alters membrane fluidity and preferentially inserts into tumor cell membranes. Edelfosine recruits death receptor ligands (FasL/CD95L, TRAIL) and Bid to lipid rafts to form death-inducing signaling complexes, thereby initiating mitochondria-dependent apoptosis and inducing cytochrome c release. Edelfosine also exerts anti-inflammatory effects, promotes L-Selectin shedding, and causes no gastrointestinal or organ toxicity. In addition, Edelfosine inhibits nucleic acid and protein synthesis in Leishmania donovani and exhibits antiproliferative activity. Edelfosine can be used in research on multiple myeloma, inflammatory bowel diseases (such as ulcerative colitis and Crohn's disease), and visceral leishmaniasis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ET-18-OCH3. CAS No. 70641-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108610A. | |
| Edelinontrine | Edelinontrine (PF-04447943) is a potent inhibitor of human recombinant PDE9A (IC50=12 nM) with >78-fold selectivity, respectively, over other PDE family members (IC50>1000 nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-04447943. CAS No. 1082744-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15441. | |
| EDI048 | EDI048 is an orally active, gut-restricted parasiticidal agent. EDI048 specifically binds to the ATP-binding site of Cryptosporidium phosphatidylinositol 4-kinase (CpPI (4) K), blocks parasite membrane biogenesis, arrests the pathogen at the schizont stage, and thus irreversibly clears the infection. EDI048 is rapidly converted to an inactive carboxylic acid metabolite via hepatic first-pass metabolism, with extremely low systemic exposure, good safety profile, and no cardiotoxicity, genotoxicity or off-target effects. EDI048 is used in studies of intestinal cryptosporidiosis in children[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2767264-57-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156685. | |
| Edicotinib | Edicotinib (JNJ-40346527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM. Edicotinib exhibits less inhibitory effects on KIT and FLT3 with IC50 values of 20 nM and 190 nM, respectively[1]. Edicotinib limits microglial expansion and attenuates microglial proliferation and neurodegeneration in mice. Edicotinib has the potential for Alzheimers disease and rheumatoid arthritis research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ-40346527; JNJ-527. CAS No. 1142363-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109086. | |
| (E)-Docosyl caffeate | (E)-Docosyl caffeate (compound 1) can be isolated from the halophytic plant Halocnemum strobilaceum[1]. Uses: Scientific research. Category: Natural products. CAS No. 28593-92-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3770. | |
| Edotreotide | Edotreotide is a ligand that selectively targets SSTR2 and can competitively bind to the receptor. Edotreotide mediates the targeted delivery, while modificated with radionuclides (such as 90Y, 177Lu, and 68Ga) to SSTR-positive tumors and induces tumor cell apoptosis by releasing β rays. Edotreotide has strong tumor targeting and precise killing activity. Edotreotide is used in the synthesis of radionuclide-drug conjugates (RDCs) and is widely used in the field of neuroendocrine tumors (such as metastatic carcinoids, lung and thymus NETs)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DOTATOC; SDZ-SMT 487; SMT 487. CAS No. 204318-14-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106033. | |
| Edoxaban | Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DU-176. CAS No. 480449-70-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10264. | |
| Edoxaban M4 | Edoxaban M4 (D21-2393) is an orally active and selective Factor Xa inhibitor with a human Factor Xa IC50 of 1.8 nM. Edoxaban M4 exhibits anticoagulant activity via Factor Xa inhibition. Edoxaban M4 can be used for the research of non-valvular atrial fibrillation, venous thromboembolisms, pulmonary embolism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D21-2393. CAS No. 834919-19-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-119124. | |
| Edoxaban tosylate monohydrate | Edoxaban (DU-176b) monohydrate is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Kis of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban monohydrate exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban monohydrate can be used for preventing thromboembolic disease research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DU-176b monohydrate. CAS No. 1229194-11-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10264B. | |
| EDTA dipotassium dihydrate | EDTA dipotassium dihydrate is a metal ion chelator that forms stable and water-soluble chelates with a variety of metal ions. EDTA dipotassium is commonly used as a blood anticoagulant, which can effectively prevent blood coagulation and maintain the morphology and function of cells in blood samples. In the industrial field, EDTA dipotassium can be used to remove the adverse effects of metal ions and prevent oxidation and deterioration caused by metal ions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethylenediaminetetraacetic acid dipotassium dihydrate. CAS No. 25102-12-9. Pack Sizes: 10 mM * 1 mL in Water; 50 g; 100 g. Product ID: HY-D0836. | |
| EDTA disodium | EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethylenediaminetetraacetic acid disodium. CAS No. 139-33-3. Pack Sizes: 10 g; 25 g. Product ID: HY-W018746. | |
| EDTA disodium (Standard) | EDTA (disodium) (Standard) is the analytical standard of EDTA (disodium). This product is intended for research and analytical applications. EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethylenediaminetetraacetic acid disodium (Standard). CAS No. 139-33-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W018746R. | |
| EDTA (iron sodium) | EDTA iron sodium (NaFeEDTA; Sodium iron EDTA) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ethylenediaminetetraacetic acid (iron sodium). CAS No. 15708-41-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g; 1 k g. Product ID: HY-131926. | |
| (E,E)-10,12-Hexadecadienal | (E,E)-10,12-Hexadecadienal is a female pheromone isolated from female Earias insulana[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 69977-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-W701835. | |
| (E,E)-Bisdemethoxycurcumin | (E,E)-Bisdemethoxycurcumin ((E,E)-Curcumin III) is a curcumin derivative with anti-inflammatory and anticancer activities[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E,E)-Curcumin III; (E,E)-Didemethoxycurcumin. CAS No. 33171-05-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0007. | |
| (E,E)-Bisdemethoxycurcumin (Standard) | (E,E)-Bisdemethoxycurcumin (Standard) is the analytical standard of (E,E)-Bisdemethoxycurcumin. This product is intended for research and analytical applications. (E,E)-Bisdemethoxycurcumin ((E,E)-Curcumin III) is a curcumin derivative with anti-inflammatory and anticancer activities[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E,E)-Curcumin III (Standard); (E,E)-Didemethoxycurcumin (Standard). CAS No. 33171-05-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0007R. | |
| EED226 | EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model[1]. EED226 is a potent, selective, and orally bioavailable EED inhibitor[2]. EED226 inhibits PRC2 with an IC50 of 23.4 nM when the H3K27me0 peptide is used as a substrate in the in vitro enzymatic assays[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2083627-02-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101117. | |
| EEDi-5285 | EEDi-5285 is an exceptionally potent and orally active embryonic ectoderm development (EED) inhibitor with an IC50 value of 0.2 nM for binds to the EED protein. EEDi-5285 has anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2488952-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136977. | |
| EEDQ | EEDQ is a carboxylate activator and irreversible antagonist of 5HT2c receptors. EEDQ reduces [3H]β-CIT binding to the dopamine transporter (DAT) in rat caudate-putamen (CPu) homogenates (IC50 = 78.3 μM). EEDQ inhibits contralateral rotation behavior[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EEDQ. CAS No. 16357-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g. Product ID: HY-Y1191. | |
| (E,?E)?-?Farnesol-d6 | (E,?E)?-Farnesol-d6 (trans,trans-Farnesol-d6) is deuterium labeled (E,?E)?-Farnesol (HY-Y0248). (E,E)-Farnesol (trans,trans-Farnesol) is a quorum-sensing molecule of Candida species. (E,E)-Farnesol can inhibit the growth, metabolism and biofilm formation of various Candida species, and affect their morphology and invasiveness[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans,trans-Farnesol-d6; (2E,6E)-Farnesol-d6. CAS No. 166447-71-8. Pack Sizes: 1 mg. Product ID: HY-Y0248AS. | |
| Eeyarestatin I | Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. Eeyarestatin I interferes at a step prior to proteasomal degradation. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 412960-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-110078. | |
| EF24 | EF24, a curcumin analogue, is an NF-kB inhibitor with great anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 is active against melanoma and breast cancer cell lines with GI50 values of 0.7 μM and 0.8 μM, respectively. EF24 induces cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells and DU-145 human prostate cancer cells. EF24 increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 342808-40-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119272. | |
| EF-5 | EF-5 (EF5; 2-Nitroimidazole) is a hypoxia labeling agent used to identify hypoxia in cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 152721-37-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00118. | |
| Efalizumab | Efalizumab is a targeted T cell modulator, and is a humanized monoclonal antibody of CD11a, the α subunit of LFA-1. Efalizumab inhibits T cell activation, cutaneous T cell trafficking, and T cell adhesion to keratinocytes, can be used for plaque psoriasis research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 214745-43-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9947. | |
| Efaroxan hydrochloride | Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 89197-00-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1416A. | |
| Efavaleukin alfa | Efavaleukin alfa (AMG592) is a IL-2 mutein fragment crystallizable fusion protein. Efavaleukin alfa drives the selective expansion of regulatory T cells. Efavaleukin alfa is applicable to research related to systemic lupus erythematosus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG592. CAS No. 2049067-94-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99877. | |
| Efavirenz | Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMP 266; EFV; L-743726. CAS No. 154598-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-10572. | |
| Efercoleukin alfa | Efercoleukin alfa is a recombinant fusion protein comprising an IL-2 fused to a human IgG1 Fc. Efercoleukin alfa binds the high-affinity IL-2 receptor alpha chain (CD25)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2760549-52-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990736. | |
| (E)-Ferulic acid | (E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-Coniferic acid. CAS No. 537-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-N0060B. | |
| (E)-Ferulic acid-d3 | (E)-Ferulic acid-d3 is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-Coniferic acid-d3. CAS No. 860605-59-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0060BS. | |
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