MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Solasodine | Solasodine (Purapuridine) is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine induces apoptosis by inhibiting the p53-MDM2 complex, p21Waf1/Cip1, and Bcl-2 proteins. Solasodine has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Purapuridine; Solancarpidine; Solasodin. CAS No. 126-17-0. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0068. |  |
| Solasonine | Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19121-58-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0070. | |
| Solcitinib | Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively; Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK-2586184; GLPG-0778. CAS No. 1206163-45-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-16755. | |
| Solifenacin | Solifenacin (YM905 free base) is a novel muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YM905 free base. CAS No. 242478-37-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0034. | |
| Solifenacin hydrochloride | Solifenacin hydrochloride (YM905 hydrochloride) is a muscarinic receptor antagonist, with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YM905 hydrochloride. CAS No. 180468-39-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-I0230. | |
| Solithromycin | Solithromycin (CEM-101) is an orally bioavailable, effective antimicrobial agent, with IC50s for inhibition of cell viability, protein synthesis, and growth rate are 7.5 ng/mL, 40 ng/mL, and 125 ng/mL for Streptococcus pneumonia, Staphylococcus aureus, and Haemophilus influenzae, respectively. Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CEM-101; OP-1068. CAS No. 760981-83-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17593. | |
| Solitomab | Solitomab (AMG 110) is a bispecific anti-CD3 and anti-epithelial-cell-adhesion-molecule (EpCAM) antibody. Solitomab can be used for the research of primary uterine and ovarian carcinosarcoma cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG 110. CAS No. 1005198-65-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99592. | |
| Solrikitug | Solrikitug is an anti-CRLF2 human IgG1 κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Signaling pathways. CAS No. 2768721-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990767. | |
| Soluflazine | Soluflazine is a nucleoside transport inhibitor with anticonvulsant action. Soluflazine can be used as an antiepileptic agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112415-83-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115366. | |
| Solutol HS-15 | Solutol HS-15, a Macrogol 15 hydroxy stearate, is a permeability enhancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Polyethylene glycol 12-hydroxystearate. CAS No. 61909-81-7. Pack Sizes: 10 g; 50 g; 100 g; 500 g. Product ID: HY-Y1893. | |
| Somatostatin-14 (3-14) | Somatostatin-14 (3-14) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1]. Uses: Scientific research. Category: Peptides. CAS No. 54518-51-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4916. | |
| Somatostatin-28 (1-14) | Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28. Uses: Scientific research. Category: Signaling pathways. CAS No. 79243-10-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1499. | |
| Somatostatin-28 (sheep, human rat mouse) | Somatostatin-28 (sheep, human rat mouse) is a biologically active polypeptide, synthesised in the proximal intestinal epithelial cells. Somatostatin-28 (sheep, human rat mouse) suppresses glucose-stimulated insulin secretion without affecting circulating basal insulin concentration. Somatostatin-28 (sheep, human rat mouse) also targets to somatostatin receptor subtype 5 (SSTR5) to regulate GLP-1 secretion[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73032-94-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P3954. | |
| SOMCL-668 | SOMCL-668 is a selective and potent sigma-1 receptor allosteric modulator. ?SOMCL-668 shows positive modulation of improvement in social deficits and cognitive impairment induced by the selective sigma-1 agonist PRE084.?SOMCL-668 displays anti-seizure activities and can be used for psychotic illness research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1422251-09-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155484. | |
| Sominone | Sominone is the active metabolite of Withanoside IV (HY-N8693). Sominone enhances neuronal morphological plasticity by activating the RET pathway. Sominone can also induce axon/dendrite regeneration and synaptic reconstruction, thereby improving spatial memory. Sominone can be used in the research of neurodegenerative diseases such as Alzheimer's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 98569-64-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N10889. | |
| Sonelokimab | Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALX 0761; M 1095. CAS No. 1414386-05-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99397. | |
| Sonepcizumab | Sonepcizumab (LT 1009) is a fully human anti-S1P monoclonal antibody. Sonepcizumab has the potential for the research of metastatic renal cell carcinoma (mRCC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LT 1009; Anti-Human S1P Recombinant Antibody. CAS No. 1031360-18-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99318. | |
| Sonesitatug | HY-P991026 is an CLDN18-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 2883771-43-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991026. | |
| Sonidegib | Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Erismodegib; LDE225; NVP-LDE225. CAS No. 956697-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-16582A. | |
| Sonidegib diphosphate | Sonidegib diphosphate (Erismodegib diphosphate) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Erismodegib diphosphate; LDE225 diphosphate; NVP-LDE225 diphosphate. CAS No. 1218778-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16582. | |
| Sonlicromanol | Sonlicromanol (KH176) is an orally active reactive oxygen species (ROS) modulator for the study in mitochondrial disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KH176. CAS No. 1541170-75-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-121577. | |
| Sonolisib | Sonolisib (PX-866), an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PX-866. CAS No. 502632-66-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6775. | |
| Sonrotoclax | Sonrotoclax is a potent, orally active Bcl2 inhibitor. Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BGB 11417. CAS No. 2383086-06-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148026. | |
| Sontigidomide | Sontigidomide (Compound 5) is an antineoplastic compound. Sontigidomide inhibits MOLM-13 cell proliferation more than 80% at 1 μM (3 days)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2560577-69-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156641. | |
| Sontuzumab | Sontuzumab (AS1402) is a humanizedised IgG1κ MUC1 specific monoclonal antibody. Sontuzumab binds the extracellular MUC1 peptide sequence PDTR with a Kd of ~1 nM. Sontuzumab can be used for the research of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AS1402; huHMFG-1; Epitumomab. CAS No. 372075-37-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99591. | |
| SOP1812 | SOP1812 (QN-302) is a naphthalene diimide (ND) derivative with anti-tumor activity. SOP1812 binds to quadruplex arrangements (G4s), and down-regulates several cancer gene pathways. SOP1812 shows great affinity to hTERT G4 and HuTel21 G4 with KD values of 4.9 and 28.4 nM, respectively. SOP1812 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: QN-302. CAS No. 2546091-70-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-148012. | |
| SOPC | SOPC (PC (18:0/18:1)) is a phosphatidylcholine lipid, which is an unsaturated phospholipid containing a cis double bond. When SOPC binds to Imatinib (HY-15463), Imatinib easily penetrates into its unsaturated liposome bilayer structure, and SOPC forms ordered, larger parallel stripe domains[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PC(18:0/18:1); 2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine. CAS No. 56421-10-4. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-W440982. | |
| Sophoflavescenol | Sophoflavescenol is a prenylated flavonol, which shows great inhibitory activity with IC50 of 0.013 μM against Phosphodiesterase 5 (PDE5), and also inhibits RLAR, HRAR, AGE, BACE1, AChE and BChE with IC50s of 0.30 μM, 0.17 μM, 17.89 μg/mL, 10.98 μM, 8.37 μM and 8.21 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 216450-65-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2284. | |
| Sophoraflavanone G | Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Kushenol F. CAS No. 97938-30-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N1231. | |
| Soquelitinib | Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8+ cells that possess enhanced T effector function[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CPI-818. CAS No. 2226636-04-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150298. | |
| Sorafenib | Sorafenib (Bay 43-9006) is a potent oral active multikinase inhibitor. Sorafenib blocks autophosphorylation and activity of receptor tyrosine kinases (VEGFR-2, VEGFR-3) and RAF family kinases, thereby suppressing the RAF/MEK/ERK and PI3K/Akt pathways, inhibiting STAT3 phosphorylation, and selectively inhibiting the MAPK pathway in cancer cells. Sorafenib induces cell cycle arrest, autophagy, apoptosis, and PARP cleavage, reduces Bcl-2, Bcl-XL, cyclin D1 levels, and activates Bak and Bax. Sorafenib inhibits tumor growth and metastasis in mouse and rat models. Sorafenib can be used for cancer research, such as colon, breast, non-small-cell lung cancer (NSCLC), ovarian, pancreatic, melanoma, colorectal and hepatocellular carcinoma[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay 43-9006. CAS No. 284461-73-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-10201. | |
| Sorafenib-13C,d3 | Sorafenib-13C,d3 is the 13C- and deuterium labeled Sorafenib. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay 43-9006-13C,d3. CAS No. 1210608-86-8. Pack Sizes: 100 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-10201S2. | |
| Sorafenib-d3 | Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Donafenib; Bay 43-9006-d3. CAS No. 1130115-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-10201S. | |
| Sorafenib (Standard) | Sorafenib (Standard) is the analytical standard of Sorafenib. This product is intended for research and analytical applications. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay 43-9006 (Standard). CAS No. 284461-73-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10201R. | |
| Sorafenib tosylate | Sorafenib (Bay 43-9006) tosylate is a potent oral active multikinase inhibitor. Sorafenib blocks autophosphorylation and activity of receptor tyrosine kinases (VEGFR-2, VEGFR-3) and RAF family kinases, thereby suppressing the RAF/MEK/ERK and PI3K/Akt pathways, inhibiting STAT3 phosphorylation, and selectively inhibiting the MAPK pathway in cancer cells. Sorafenib tosylate induces cell cycle arrest, autophagy, apoptosis, and PARP cleavage, reduces Bcl-2, Bcl-XL, cyclin D1 levels, and activates Bak and Bax. Sorafenib tosylate inhibits tumor growth and metastasis in mouse and rat models. Sorafenib tosylate can be used for cancer research, such as colon, breast, non-small-cell lung cancer (NSCLC), ovarian, pancreatic, melanoma, colorectal and hepatocellular carcinoma[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay 43-9006 tosylate. CAS No. 475207-59-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-10201A. | |
| Soraprazan | Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H,K-ATPase (Ki=6.4 nM), with an IC50 of 0.19 μM in gastric glands. Soraprazan binds to the H,K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H,K-ATPase over Na,K- and Ca-ATPases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BYK61359. CAS No. 261944-46-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100414. | |
| Sorbifolin | Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23130-22-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N11552. | |
| Sorbinil | Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway. Uses: Scientific research. Category: Signaling pathways. CAS No. 68367-52-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50289. | |
| SOR-C13 | SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1187852-48-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1651. | |
| Sordarin sodium | Sordarin sodium is an eEF2 inhibitor and antibiotic. Sordarin sodium's function is dependent on the diphthamide modification on eEF2. Sordarin sodium inhibits protein synthesis by preventing the binding of eEF2 to the ribosome complex. Sordarin sodium has antifungal activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 463356-00-5. Pack Sizes: 1 mg. Product ID: HY-126396. | |
| Sortase A, S. aureus | Sortase A, S. aureus (SrtA), a transpeptidase enzyme is present in many Gram-positive bacteria and helps in the recruitment of the cell surface proteins. Sortase A, S. aureus plays an important part in ligation of various molecules on the cell surfaces[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SrtA. CAS No. 9033-39-0. Pack Sizes: 50 μg; 100 μg. Product ID: HY-E70234. | |
| Sortilin antagonist 1 | Sortilin antagonist 1 (compound 44) is a sortilin antagonist with an IC50 value of 20 nM for inhibiting Neurotensin (NTS) binds to sortilin. Neurotensin is a sortilin ligand. Sortilin antagonist 1 can be used for the research of neurological disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2691846-93-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148650. | |
| SOS1-IN-14 | SOS1-IN-14 is a potent, selective and orally active SOS1 inhibitor with an IC50 value of 3.9 nM. SOS1-IN-14 can be absorbed in the intestine via a P-glycoprotein-mediated efflux mechanism. SOS1-IN-14 can be used to research KRAS-mutated cancers. SOS1-IN-14 has better potent tumor suppression than BI-3406 (HY-125817)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2793405-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151517. | |
| Sotagliflozin | Sotagliflozin (LX-4211) is a potent dual SGLT2/1 inhibitor. Antidiabetic agents. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LX-4211; LP-802034. CAS No. 1018899-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15516. | |
| Sotalol hydrochloride | Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MJ 1999. CAS No. 959-24-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0437. | |
| Sotatercept | Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACE-011; MK-7962. CAS No. 1001080-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99590. | |
| Sotevtamab | Sotevtamab (16B5) is a humanized IgG2 anti-clusterin monoclonal antibody (mAb). Sotevtamab is an inhibitor of the epithelial to mesenchymal transition. Sotevtamab can be used for cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 16B5; AB-16B5. CAS No. 2411526-47-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99589. | |
| Soticlestat | Soticlestat (TAK-935; OV935) is a first-in-class, potent, selective, and orally active cholesterol 24-hydroxylase (CH24H) inhibitor. Soticlestat has the potential for epilepsy syndromes research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-935; OV935. CAS No. 1429505-03-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109123. | |
| Sotigalimab | Sotigalimab, a CD40 agonistic monoclonal antibody. Sotigalimab binds CD40 with high affinity and activates antigen-presenting cells, thereby stimulating cancer-specific T cell responses. Sotigalimab is mainly used in the study of metastatic pancreatic cancer and metastatic melanoma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APX005M; APX005M; EPI-0050. CAS No. 2305607-45-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99049. | |
| Sotorasib | Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C - mutated locally advanced or metastatic non - small cell lung cancer (NSCLC)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG-510. CAS No. 2296729-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-114277. | |
| Sotorasib (Standard) | Sotorasib (Standard) is the analytical standard of Sotorasib. This product is intended for research and analytical applications. Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C - mutated locally advanced or metastatic non - small cell lung cancer (NSCLC)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG-510 (Standard). CAS No. 2296729-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114277R. | |
| Sotrastaurin | Sotrastaurin (AEB071) is a potent and orally-active pan-PKC inhibitor, with Kis of 0.22 nM, 0.64 nM, 0.95 nM, 1.8 nM, 2.1 nM and 3.2 nM for PKCθ, PKCβ, PKCα, PKCη, PKCδ and PKCε, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEB071. CAS No. 425637-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10343. | |
| Sotrovimab | Sotrovimab (VIR 7831) is a human IgG1κ pan-sarbecovirus monoclonal antibody (mAb), neutralizes SARS-CoV-2, SARS-CoV-1, and multiple other sarbecoviruses. Sotrovimab is developed based on S309, exhibits a long half-life and great bioavailability in the respiratory mucosa. Sotrovimab could result in immune-mediated viral clearance and prevent progression of Covid-19 early in the course of disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VIR 7831; GSK-4182136. CAS No. 2423014-07-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99340. | |
| Sotuletinib | Sotuletinib (BLZ945) is a potent, selective, orally active and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. Sotuletinib can be used for microglia depletion, and for tumor and CNS-related disease research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BLZ945. CAS No. 953769-46-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12768. | |
| Sotuletinib hydrochloride | Sotuletinib (BLZ945) hydrochloride is a potent, selective, orally active and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. Sotuletinib hydrochloride can be used for microglia depletion, and for tumor and CNS-related disease research.[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BLZ945 hydrochloride. CAS No. 2222138-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12768A. | |
| Sovesudil | Sovesudil (PHP-201) is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil lowers intraocular pressure (IOP) without inducing hyperemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PHP-201; AMA0076. CAS No. 1333400-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-109191. | |
| Sovesudil hydrochloride | Sovesudil (PHP-201) hydrochloride is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil hydrochloride lowers intraocular pressure (IOP) without inducing hyperemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PHP-201 hydrochloride; AMA0076 hydrochloride. CAS No. 2984963-50-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109191A. | |
| Sovilnesib | Sovilnesib (AMG 650) is a potent, orally active kinesin-like protein KIF18A inhibitor with an IC50 value of 0.071 μM. Sovilnesib can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG 650. CAS No. 2410796-79-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132840. | |
| Sovleplenib | Sovleplenib (HMPL-523) is a highly potent, orally available and selective SYK inhibitor with an IC50 of 25 nM. Anti-tumor activity. Sovleplenib can be used for the research of immune thrombocytopenia (ITP)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMPL-523. CAS No. 1415792-84-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145598. | |
| Soyasapogenol A | Soyasapogenol A is a triterpenoid aglycone of soyasaponins. Soyasapogenol A has activities such as anti-inflammation, anti-cancer, hepatoprotection and anti-HSV-1. Soyasapogenol A can be used in the research of tumors and immune inflammatory diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 508-01-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6073. | |
| Soyasapogenol B | Soyasapogenol B is a component of soy that has oral activity. Soyasapogenol B promotes autophagy and apoptosis. Soyasapogenol B has anti-inflammatory, antioxidant and antitumor activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 595-15-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6074. | |
| Soyasaponin Ab | Soyasaponin Ab is an orally active soyasaponin. Soyasaponin Ab inhibits PPARγ transcriptional activity. Soyasaponin Ab induces apoptosis in high concentrations. Soyasaponin Ab exerts anti-obesity, anti-oxidation, anti-inflammation, anti-aging effects. Soyasaponin Ab prevents Scopolamine (HY-N0296)-induced memory impairment[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118194-13-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N3026. | |
| Soyasaponin Ba | Soyasaponin Ba is a soyasaponin that can be isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitor (ARI). Soyasaponin Ba activates Akt/GSK3β/β-catenin signaling pathway, reduces lipid accumulation, lowers ROS generation, improves mitochondrial membrane potential, ATP levels, and morphology, and inhibits apoptosis. Soyasaponin Ba can be used for the research of lipid accumulation and secondary diabetic complications[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114590-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N0309. | |
| Soyasaponin Bb | Soyasaponin Bb is an orally active, covalent inducer of heme oxygenase HO-1 and an inhibitor of aldose reductase AKR1B1. Soyasaponin Bb can regulate oxidative stress pathways, enhance antioxidant capacity, reduce reactive oxygen species (ROS) generation, and inhibit lipid peroxidation and hepatocyte apoptosis. Soyasaponin Bb improves alcohol-induced hepatocyte membrane damage and liver function abnormalities, and improves Scopolamine (HY-N0296)-induced memory impairment. Soyasaponin Bb has antioxidant, hepatoprotective, and neuroprotective activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51330-27-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-N0310. | |
| SP-100030 | SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor (IC50s=50 and 50 nM, respectively). SP-100030 inhibits IL-2, IL-8, and TNF-alpha production in Jurkat and other T cell lines. SP-100030 decreases murine collagen-induced arthritis (CIA)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154563-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110177. | |
| SP11 | SP11 is a mitochondrial fission protein 1 (Fis1) inhibitor with an IC50 of 9.4 μM. SP11 binds only to activated Fis1 by engaging Cys41. SP11 preserves mitochondrial integrity and function during oxidative stress, inhibits hydrogen peroxide-induced mitochondrial ROS production, mitochondrial fragmentation, and Drp1 mitochondrial translocation. SP11 can be used for the research of parkinsons disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2629218-24-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172942. | |
| SP-141 | SP-141 is a specific inhibitor of MDM2. SP-141 promotes MDM2 auto-ubiquitination and degradation. SP-141 might be used for the research of pancreatic cancer and breast cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1253491-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110182. | |
| SP187 | SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MON-DNJ; UV4. CAS No. 615253-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00160. | |
| SP2509 | SP2509 is a potent and selective antagonist of lysine specific demethylase 1 (LSD1) with an IC50 of 13 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1423715-09-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12635. | |
| SP27 | SP27 is a PROTAC that can selective degrades PLK4, with a DC50 of 19.5 nM. SP27 can be used for the research of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3034805-75-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149324. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.