MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Biotin-epoxomicin | Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334608-28-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11307. |  |
| Biotin-hexanamide-(L-Thyroxine) | Biotin-hexanamide-(L-Thyroxine) is biotinylated L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2278192-78-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-18341F1. | |
| Biotin-HPDP | Biotin-HPDP is a biochemical reagent. Biotin-HPDP can couple with GMPS and label free protein thiols. Biotin-HPDP can be used as a biological material or organic compound for life science related research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129179-83-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136769. | |
| Biotin Hydrazide | Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe. Uses: Scientific research. Category: Signaling pathways. CAS No. 66640-86-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-100215. | |
| Biotin LC hydrazide | Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Biotinamidocaproyl hydrazide; BACH; (+)-Biotinamidohexanoic Acid hydrazide; Biotin Aminocaproyl Hydrazide. CAS No. 109276-34-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101885. | |
| Biotin-maleimide | Biotin-maleimide is a biotinylated biochemical detection reagent that acts as a thiol-specific probe. Biotin-maleimide can also be used to prepare biotin-conjugated polychelators[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 116919-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W808757. | |
| Biotin methyl ester | Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 608-16-2. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg; 1 g. Product ID: HY-W107202. | |
| Biotin-naphthylamine | Biotin-naphthylamine is a biotinylated biochemical assay reagent, which is a substrate for ascorbate peroxidase 2 (APEX2). Biotin-naphthylamine is utilized as a novel probe for labeling DNA and RNA[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2375201-60-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-W614753. | |
| Biotin NHS | Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Biotin N-hydroxysuccinimide ester; NHS-Biotin. CAS No. 35013-72-0. Pack Sizes: 100 mg; 200 mg. Product ID: HY-D0802. | |
| Biotin-(Oaa)3-epoxomicin | Biotin-(Oaa)3-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)3-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 247068-92-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P11306. | |
| Biotinoyl tripeptide-1 | Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Biotinyl-GHK; Bio-GHK. CAS No. 299157-54-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-125616. | |
| Biotin-PEG11-azide | Biotin-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG11-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2276672-04-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140912. | |
| Biotin-PEG11-Mal | Biotin-PEG11-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1646619-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140909. | |
| BIOTIN-PEG11-SH | BIOTIN-PEG11-SH enables biotin labeling of protein. Uses: Scientific research. Category: Signaling pathways. CAS No. 1650579-23-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-145445. | |
| Biotin-PEG12-NHS ester | Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1934296-88-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140892. | |
| Biotin-PEG1-NH2 | Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 811442-85-0. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W096135. | |
| Biotin-PEG2-acid | Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1365655-89-5. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-126958. | |
| Biotin-PEG2-aldehyde | Biotin-PEG2-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2743939-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133456. | |
| Biotin-PEG2-C2-iodoacetamide | Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 292843-75-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140941. | |
| Biotin-PEG3400-azide | Biotin-PEG3400-azide is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 956494-20-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W250928D. | |
| Biotin-PEG3-azide | Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 875770-34-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130143. | |
| Biotin-PEG3-benzophenone | Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 756525-96-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D2353. | |
| Biotin-PEG3-Bromide | Biotin-PEG3-Bromide is a short PEG linker featuring a biotin group and a bromide. The bromide is a halogen which is easily displaced by nucleophiles such as alcohols or amines. Alternatively, bromide can be applied in a number of cross-coupling reactions such as in a Suzuki reaction. Biotin is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins. Uses: Scientific research. Category: Signaling pathways. CAS No. 1041766-91-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-101974. | |
| Biotin-PEG3-CONH-Ph-CF3-diazirine | Biotin-PEG3-CONH-Ph-CF3-diazirine is a biotin labeled PEG3 derivative. Biotin-PEG3-CONH-Ph-CF3-diazirine can be used for protein labeling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2845211-64-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154801. | |
| Biotin-PEG3-Iodoacetamide | Biotin-PEG3-Iodoacetamide is a PEG derivative composed of Biotin, 3 PEG units, and Iodoacetamide. Biotin can form a stable non-covalent bond with streptavidin. Uses: Scientific research. Category: Signaling pathways. CAS No. 2306161-26-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174938. | |
| Biotin-PEG3-oxyamine | Biotin-PEG3-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1786206-22-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140938. | |
| Biotin-PEG3-SH | Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1244028-52-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-132115. | |
| Biotin-PEG3-SS-azide | Biotin-PEG3-SS-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Biotin-PEG3-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2866429-93-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-140944. | |
| Biotin-PEG4-acid | Biotin-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 721431-18-1. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126959. | |
| Biotin-PEG4-alkyne | Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1458576-00-5. Pack Sizes: 5 mg; 10 mg; 100 mg. Product ID: HY-140922. | |
| Biotin-PEG4-Amide-C6-Azide | Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-Amide-C6-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1006592-62-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-140914. | |
| Biotin-PEG4-amine | Biotin-PEG4-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 663171-32-2. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-140895. | |
| Biotin-PEG4-amino-t-Bu-DADPS-C6-azide | Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1260247-50-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-140921. | |
| Biotin-PEG4-azide | Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1309649-57-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-140910. | |
| Biotin-PEG4-mal | Biotin-PEG4-mal is a PEG derivative composed of Biotin, 4 PEG units and Maleimide. Biotin can form a stable non-covalent bond with streptavidin. Uses: Scientific research. Category: Signaling pathways. CAS No. 1604673-42-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174914. | |
| Biotin-PEG4-methyltetrazine | Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1835759-81-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140940. | |
| Biotin-PEG4-NHS ester | Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 459426-22-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-140889. | |
| Biotin-PEG4-Picolyl azide | Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2222687-71-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140915. | |
| Biotin-PEG(4)-SS-Alkyne | Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an alkyne group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1260247-54-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151649. | |
| Biotin-PEG5-amine | Biotin-PEG5-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 113072-75-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140896. | |
| Biotin-PEG5-azide | Biotin-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1163732-89-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-133174. | |
| Biotin-PEG6-azide | Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1085938-09-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-140911. | |
| Biotin-PEG6-NHS ester | Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055045-04-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-140890. | |
| Biotin-PEG7-amine | Biotin-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334172-76-7. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-140898. | |
| Biotin-PEG7-azide | Biotin-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334172-75-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-133175. | |
| Biotin-PEG7-Maleimide | Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1898221-65-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156377. | |
| Biotin-PEG8-acid | Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2143964-62-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-140492. | |
| Biotin-PEG8-alcohol | Biotin-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2182601-20-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-140894. | |
| Biotin-PEG8-Alkyne | Biotin-PEG8-Alkyne is an azide reactive compound[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2143968-80-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156379. | |
| Biotin-PEG8-amine | Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2183447-27-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-140899. | |
| Biotin-PEG9-amine | Biotin-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 960132-48-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W190970. | |
| Biotin (Standard) | Biotin (Standard) is the analytical standard of Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B7 (Standard); Vitamin H (Standard); D-Biotin (Standard). CAS No. 58-85-5. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-B0511R. | |
| Biotin-Thalidomide | Biotin-Thalidomide is a biotin-conjugated Thalidomide (HY-14658) for binding to CRBN. Biotin-Thalidomide can be used to synthesize PROTAC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230857-87-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-145152. | |
| Biotin-VAD-FMK | Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135688-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100894. | |
| Biotin-X-NTA | Biotin-X-NTA can be used for detecting histidine-tagged proteins immobilized on nitrocellulose membranes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 856661-92-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147169. | |
| Biotin-XX hydrazide | Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Biotin-(AC5)2-hydrazide. CAS No. 211237-33-1. Pack Sizes: 5 mg. Product ID: HY-125501. | |
| Biotinylated isoxazole | Biotinylated isoxazole is a biotinylated derivative of Isoxazole (HY-W010649). Biotinylated isoxazole is capable of triggering the formation of aggregates related to RNA granules[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1377605-22-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W750960. | |
| Biotinylated-JQ1 | Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Biotin-JQ1. CAS No. 1635437-52-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145667. | |
| Biotinyl-neuropeptide W-23 (human) | Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1815618-09-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3844. | |
| Biotinyl tyramide | Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 41994-02-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-125658. | |
| Bioymifi | Bioymifi (DR5 Activator), a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DR5 Activator. CAS No. 1420071-30-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18377. | |
| BIP-135 | BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 941575-71-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111055. | |
| Biperiden | Biperiden (KL 373) is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden has the potential for the research of Parkinson's disease and other related psychiatric disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KL 373. CAS No. 514-65-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13204A. | |
| Biphenyl-4-amidoxime | Biphenyl-4-amidoxime (N'-hydroxy-4-phenylbenzene-1-carboximidamide) is a synthetic intermediate useful for pharmaceutical synthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N'-hydroxy-4-phenylbenzene-1-carboximidamide. CAS No. 40019-44-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-129844. | |
| BiP inducer X | BiP inducer X, a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78, is an effective ER (endoplasmic reticulum) stress inhibitor. BiP inducer X preferentially induces BiP with slight inductions of GRP94, calreticulin, and C/EBP homologous protein. BiP inducer X protects neurons from ER stress[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 101714-41-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110188. | |
| Birabresib | Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OTX-015; MK-8628. CAS No. 202590-98-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15743. | |
| Biricodar | Biricodar (VX-710) is a modulator of P-glycoprotein and MRP-1; shows effective chemosensitizing activity in multidrug resistant cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-710. CAS No. 159997-94-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13574A. | |
| Birinapant | Birinapant (TL32711), a bivalent Smac mimetic, is a potent antagonist for XIAP and cIAP1 with Kds of 45 nM and less than 1 nM, respectively. Birinapant (TL32711) induces the autoubiquitylation and proteasomal degradation of cIAP1 and cIAP2 in intact cells, which results in formation of a RIPK1: caspase-8 complex, caspase-8 activation, and induction of tumor cell death. Birinapant (TL32711) targets TRAF2-associated cIAPs and abrogates TNF-induced NF-κB activation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TL32711. CAS No. 1260251-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16591. | |
| BIRT 377 | BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1). BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 213211-10-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110117. | |
| Birtamimab | Birtamimab (NEOD001) is an investigational monoclonal antibody that specifically and selectively target and clear the amyloid. Birtamimab can be used for the research of light chain amyloidosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NEOD001. CAS No. 1608108-91-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99481. | |
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