MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| (-)-β-Peltatin | (-)-β-Peltatin is an organic heterotetracyclic compound with antitumor activity and phytometabolite effects that are functionally related to α-peltatin [1]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Peltatin. CAS No. 518-29-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-125135. |  |
| β-Phellandrene | β-phellandrene is an orally active monocyclic monoterpenes. β-Phellandrene is obtained from Carum petroselinum. β-phellandrene has strong ability to kill pest. β-phellandrene can be used as oil additives, natural pesticides and synthetic materials [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 555-10-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8573. | |
| β-Pompilidotoxin | β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells [1]. Uses: Scientific research. Group: Peptides. Alternative Names: β-PMTX. CAS No. 216064-36-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1084. | |
| β-Secretase Inhibitor IV | β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC 50 s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 797035-11-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10133. | |
| Beta-Sitosterol (purity>80%) | Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>80%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-46-5. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-N0171. | |
| β-Tocopherol | β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 16698-35-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-133680. | |
| β-Tocotrienol | β-Tocotrienol is one form of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 490-23-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108693. | |
| Betaxolol | Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. Uses: Scientific research. Group: Signaling pathways. CAS No. 63659-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0381. | |
| Betaxolol hydrochloride | Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL75212. CAS No. 63659-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0381A. | |
| Beta-Zearalanol | Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells [1]. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid [2]. Uses: Scientific research. Group: Natural products. CAS No. 42422-68-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6740. | |
| β-Zearalenol | β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level [1]. Uses: Scientific research. Group: Natural products. CAS No. 71030-11-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6741. | |
| BET bromodomain inhibitor | BET bromodomain inhibitor is a potent BET inhibitor extracted from patent WO/2015/153871A2, compound example 11. Uses: Scientific research. Group: Signaling pathways. CAS No. 1505453-59-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103036. | |
| BET bromodomain inhibitor 3 | BET bromodomain inhibitor 3 is BET bromodomain inhibitor. BET bromodomain inhibitor 3 has inhibitory effect against BrdT with K i value of > 40 μM. BET bromodomain inhibitor 3 can be used for the research of contraception, cancer, and heart disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 854137-39-6. Pack Sizes: 10 mg. Product ID: HY-153593. | |
| BET bromodomain inhibitor 4 | BET bromodomain inhibitor 4 (example 7) is an inhibitor of the BET bromodomain domain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407658-41-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-157393. | |
| Bethanechol chloride | Bethanechol chloride (Carbamyl-β-methylcholine chloride), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Carbamyl-β-methylcholine chloride. CAS No. 590-63-6. Pack Sizes: 10 mM * 1 mL; 200 mg; 5 g. Product ID: HY-B0406A. | |
| BET-IN-14 | BET-IN-14 is an orally active pan BET inhibitor ( IC 50 : 5.35 nM). BET-IN-14 has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2243669-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-153226. | |
| Betrixaban | Betrixaban (PRT054021) is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor with an IC 50 of 1.5 nM. Betrixaban shows antithrombotic effect [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRT054021. CAS No. 330942-05-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10268. | |
| Betulin | Betulin (Trochol), is a sterol regulatory element-binding protein ( SREBP ) inhibitor with an IC 50 of 14.5 μM in K562 cell line. Uses: Scientific research. Group: Natural products. Alternative Names: Trochol. CAS No. 473-98-3. Pack Sizes: 50 mg; 100 mg; 200 mg. Product ID: HY-N0083. | |
| Betulinic acid | Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC 50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Lupatic acid; Betulic acid. CAS No. 472-15-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10529. | |
| Bevacizumab | Bevacizumab, a humanized IgG1 monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human VEGF, Humanized Antibody. CAS No. 216974-75-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9906. | |
| Bevantolol hydrochloride | Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pK i values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca 2+ antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 42864-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121186. | |
| Bevenopran | Bevenopran is a peripheral μ-opioid receptor antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CB-5945; ADL-5945. CAS No. 676500-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100122. | |
| Bevirimat | Bevirimat (PA-457, MPC-4326, YK FH312) is an inhibitor of HIV-1 viral particle maturation.Bevirimat specifically inhibits the final rate-limiting step in Gag processing, preventing the release of the mature capsid protein (CA) from its precursor (CA-SP1), resulting in the production of immature non-infectious viral particles. Bevirimat can be used in HIV-1 infection studies [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: PA-457; MPC-4326; YK FH312. CAS No. 174022-42-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0842. | |
| Bexarotene | Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors ( RXR ) agonist with EC 50 s of 33, 24, 25 nM for RXRα , RXRβ , and RXRγ , respectively. Bexarotene shows limited affinity for RAR receptors (EC 50 >10000 nM) [1] [2] [3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGD1069. CAS No. 153559-49-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-14171. | |
| Bexicaserin | Bexicaserin (LP352) is a 5-HT2C receptor agonist with potential for studying obesity and psychiatric-related disorders (such as epilepsy) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LP352. CAS No. 2035818-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156601. | |
| Bexmarilimab | Bexmarilimab (FP-1305) is a potent humanized anti- CLEVER-1 IgG4-antibody with an IC 50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FP-1305. CAS No. 2259301-27-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99236. | |
| Bexotegrast | Bexotegrast (PLN-74809) is an orally active, potent dual αvβ6/αvβ1 integrin inhibitor with K d of 5.7 nM and 3.4 nM, respectively. Bexotegrast inhibits αvβ6- and αvβ1-induced TGF-β activation with IC 50 values of 29.8 nM and 19.2 nM, respectively. Bexotegrast has antifibrogenic effects and block multiple avenues of TGF-β activation in the fibrotic lung [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLN-74809. CAS No. 2376257-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137561. | |
| Bezafibrate | Bezafibrate is an agonist of PPAR , with EC 50 s of 50 μM, 60 μM, 20 μM for human PPARα , PPARγ and PPARδ , and 90 μM, 55 μM, 110 μM for murine PPARα , PPARγ and PPARδ , respectively; Bezafibrate is used as an hypolipidemic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BM15075. CAS No. 41859-67-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0637. | |
| Bezisterim | Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis [1] [2] [3]. Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HE 3286; NE-3107. CAS No. 1001100-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108039. | |
| Bezlotoxumab | Bezlotoxumab is a human monoclonal antibody directed against C. difficile toxin B. Bezlotoxumab binds to C. difficile toxin B preventing intestinal epithelial damage and colitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1246264-45-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9929. | |
| Bezuclastinib | Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor with potent activity against KIT D816V. Bezuclastinib can be used for the research of nonadvanced systemic mastocytosis (NonAdvSM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGT9486; PLX 9486. CAS No. 1616385-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145557. | |
| BGC-20-1531 free base | BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP 4 receptor antagonist, with a pK B of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PGN 1531 free base. CAS No. 736183-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19849. | |
| BI 224436 | BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC 50 values of less than 15 nM against different HIV-1 laboratory strains. Uses: Scientific research. Group: Signaling pathways. CAS No. 1155419-89-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18595. | |
| BI-2545 | BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC 50 s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2162961-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124772. | |
| BI-4394 | BI-4394 (MMP13-IN-3) is a potent, selective, and orally active MMP-13 inhibitor ( IC 50=1 nM [1] ) for the potential treatment of osteoarthritis [2]. BI-4394 is >1000 selective over other MMPs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MMP13-IN-3. CAS No. 1222173-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124029. | |
| BI 639667 | BI 639667 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist, with an IC 50 of 1.8 nM in Ca 2+ flux assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCR1 antagonist 8. CAS No. 1295298-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-120588. | |
| BI 99179 | BI 99179 is a potent and selective type I fatty acid synthase ( FAS ) inhibitor with an IC 50 of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1291779-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16100. | |
| BIA 10-2474 | BIA 10-2474 is an inhibitor of fatty acid amide hydrolase ( FAAH ) with IC 50 values of 50 to 70mg/kg in various rat brain regions. Uses: Scientific research. Group: Signaling pathways. CAS No. 1233855-46-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19740. | |
| Bialaphos sodium | Bialaphos (SF-1293) sodium, an antibiotic , is an effective herbicide is a metabolite of Streptomyces hygroscopicus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SF-1293 sodium. CAS No. 71048-99-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122494A. | |
| Biapenem | Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CLI 86815; L 627; LJC 10627. CAS No. 120410-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13573. | |
| BIBP3226 TFA | BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with K i s of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1068148-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107726. | |
| BIBR 1532 | BIBR 1532 is a potent, selective and non-competitive telomerase inhibitor with IC 50 of 100 nM in a cell-free assay. Uses: Scientific research. Group: Signaling pathways. CAS No. 321674-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17353. | |
| BIBS 39 | BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 133085-33-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19732. | |
| Bicalutamide | Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90357-06-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-14249. | |
| Bicarbonate-13C sodium | Bicarbonate- 13 C (sodium) is the 13 C labeled Bicarbonate sodium[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 87081-58-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W251598S. | |
| Bicine | Bicine is a buffer used in physiological research. Bicine is a derivative of the simple amino acid glycine that increases the sensitivity of guanosine enzyme histochemical detection [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150-25-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0868. | |
| Bictegravir | Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC 50 of 7.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883. CAS No. 1611493-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605. | |
| Bictegravir sodium | Bictegravir sodium is a potent inhibitor of HIV-1 integrase , with an IC 50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883 sodium. CAS No. 1807988-02-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605A. | |
| Bicuculline | Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABA A receptor antagonist ( IC 50 =2 μM). Bicuculline also blocks Ca 2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Bicuculline; d-Bicuculline. CAS No. 485-49-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0219. | |
| Bicuculline methiodide | Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Bicuculline methiodide; l-Bicuculline methiodide. CAS No. 40709-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103474. | |
| (-)-Bicuculline methobromide | (-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABA A receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca 2+ -activated K + channels in various types of neurons [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: l-Bicuculline methobromide. CAS No. 73604-30-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100783. | |
| Bicuculline methochloride | Bicuculline ((+)-Bicuculline; d-Bicuculline) methochloride is a selective GABAA receptor antagonist with an IC 50 value of 3 μM. Bicuculline methochloride induces clonic tonic convulsions in mammals and can also be used to block Ca 2+ activated potassium channels. Bicuculline methochloride can be used in studies of epilepsy and other related psychiatric disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Bicuculline methochloride; l-Bicuculline methochloride. CAS No. 38641-83-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137790. | |
| Bicyclol | Bicyclol (SY801) is an orally active derivative of the traditional Chinese medicine Schisandra chinensis, which has antiviral, anti-inflammatory, immunomodulatory, antioxidant, anti-steatosis, anti-fibrotic and anti-tumor activities. Bicyclol regulates the expression of heat shock proteins and plays an anti- apoptosis role in hepatocytes. Bicyclol reduces the activation of NF-κB and the levels of inflammatory factors in hepatocytes infected with hepatitis C virus (HCV) by inhibiting the activation of the ROS-MAPK-NF-κB pathway, and prevents ferroptosis in acute liver injury. Bicyclol can change the expression of Mdr-1 , GSH/GST and Bcl-2 , increase the intracellular concentration of anticancer drugs, and sensitize drug-resistant cells to anticancer drugs. Bicyclol inhibits the proliferation of human malignant hepatoma cells by regulating the PI3K/AKT pathway and the Ras/Raf/MEK/ERK pathway. Bicyclol can be used in the study of chronic hepatitis, acute liver injury, nonalcoholic fatty liver disease, liver fibrosis and hepatocellular carcinoma [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SY801. CAS No. 118159-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0766. | |
| Bicyclomycin benzoate | Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FR2054. CAS No. 37134-40-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101128. | |
| Bidisomide | Bidisomide (SC40230) is a class I antiarrhythmic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC40230. CAS No. 116078-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-U00232. | |
| Bifemelane hydrochloride | Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A) , with a K i of 4.20 μM. Bifemelane hydrochloride also inhibits MAO-B noncompetitively with a K i of 46.0 μM. Bifemelane hydrochloride has a potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-2016. CAS No. 62232-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1558A. | |
| Bifenazate | Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm [1]. Bifenazate is a positive allosteric modulator of GABA receptor [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149877-41-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-119687. | |
| Bifendate | Bifendate (DDB), extracted from Schisandrae chinensis , is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins ( CYPs ) and reverse P-gp -mediated multi-drug resistance (MDR) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDB. CAS No. 73536-69-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W018791. | |
| Bifenthrin | Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels , leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae ( LD 50 =0.15 ng/mg) and C. quinquefasciatus ( LD 50 =0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82657-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0824. | |
| Bifeprunox mesylate | Bifeprunox mesylate is a potent dopamine D2 -like and 5-HT1A receptor partial agonist with pK i s of 7.19 and 8.83 for cortex 5-HT1A and striatum D2, and a pEC 50 of 6.37 for hippocampus 5-HT1A, respectively. Bifeprunox mesylate is an antipsychotic for the research of schizophrenia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 350992-13-1. Pack Sizes: 5 mg. Product ID: HY-14547A. | |
| Bifonazole | Bifonazole (Bay H-4502) is an imidazole antifungal agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bay H-4502. CAS No. 60628-96-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0301. | |
| Biguanide | Biguanide is an orally active antihyperglycemic agent. Biguanide inhibits mitochondrial ATP production, activates the LKB1-AMPK signaling pathway, and damages the energy homeostasis. Biguanide exhibits potential in ameliorating the type 2 diabetes and the insulin-associated cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 56-03-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121006. | |
| BIIB021 | BIIB021 (CNF2024) is an orally active, fully synthetic inhibitor of HSP90 with a K i and an EC 50 of 1.7 nM and 38 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CNF2024. CAS No. 848695-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10212. | |
| BIIB091 | BIIB091 is a potent, selective, orally active and reversible BTK inhibitor, with an IC 50 of <0.5 nM. BIIB091 binds the BTK protein to sequester TYR-551 into an inactive conformation with excellent affinity. BIIB091 can be used for the research of multiple sclerosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2247614-80-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139984. | |
| BIIE-0246 | BIIE-0246 (AR-H 053591) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC 50 value of 15 nM for rat [ 125 I]PYY 3-36. BIIE-0246 decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 reduces albuminuria in ADR nephropathy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-H 053591. CAS No. 246146-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101986. | |
| BIIL-260 hydrochloride | BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB 4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB 4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB 4 receptor on isolated human neutrophil cell membranes with K i values of 1.7 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 192581-24-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114641A. | |
| Bikaverin | Bikaverin (Lycopersin) is a reddish pigment produced by different fungal species. Bikaverin shows antibiotic properties against certain protozoa and fungi [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Lycopersin. CAS No. 33390-21-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-121004. | |
| Bilastine | Bilastine is an oral histamine H1-receptor antagonist. Bilastine can be used for allergic rhinitis and urticaria studies, and it also improves diabetic nephropathy in mice, showing safety for the central nervous system [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202189-78-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-14447. | |
| Bile extract | Bile extract is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ox bile extract. CAS No. 8008-63-7. Pack Sizes: 5 g. Product ID: HY-N8332. | |
| Biliatresone | Biliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-propenone class of isoflavonoid, produces extrahepatic biliary atresia in a zebrafish model [1]. Uses: Scientific research. Group: Natural products. CAS No. 1801433-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119412. | |
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